Sarah M. McLeod, Ph.D.
Affiliations: | 2001 | University of California, Los Angeles, Los Angeles, CA |
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"Sarah McLeod"Parents
Sign in to add mentor| Reid Johnson | grad student | 2001 | UCLA | |
| (Architecture of the Fis and CRP co-activated proP P2 transcription initiation complex.) | ||||
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Publications
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| Durand-Reville TF, Comita-Prevoir J, Zhang J, et al. (2020) Discovery of an Orally Available Diazabicyclooctane Inhibitor (ETX0282) of Class A, C and D Serine β-lactamases. Journal of Medicinal Chemistry |
| Miller AA, Shapiro AB, McLeod S, et al. (2020) In vitro Characterization of ETX1317, a broad-spectrum β-lactamase inhibitor that restores and enhances β-lactam activity against multidrug resistant Enterobacteriales, including carbapenem-resistant strains. Acs Infectious Diseases |
| McLeod SM, Moussa SH, Hackel MA, et al. (2020) activity of sulbactam-durlobactam against complex isolates collected globally from 2016-2017. Antimicrobial Agents and Chemotherapy |
| Miller A, McLeod S, Mathur T, et al. (2019) 694. In vitro Antibacterial Activity of Sulbactam–Durlobactam (ETX2514SUL) Against 121 Recent Acinetobacter baumannii Isolated from Patients in India Open Forum Infectious Diseases. 6: S314-S314 |
| McLeod SM, Shapiro AB, Moussa SH, et al. (2017) The frequency and mechanism of spontaneous resistance to sulbactam combined with the novel β-lactamase inhibitor ETX2514 in clinical isolates of Acinetobacter baumannii. Antimicrobial Agents and Chemotherapy |
| Durand-Réville TF, Guler S, Comita-Prevoir J, et al. (2017) ETX2514 is a broad-spectrum β-lactamase inhibitor for the treatment of drug-resistant Gram-negative bacteria including Acinetobacter baumannii. Nature Microbiology. 2: 17104 |
| McLeod SM, Patey SA, Huband MD, et al. (2017) Impact of defined cell envelope mutations in Escherichia coli on the in vitro antibacterial activity of avibactam/β-lactam combinations. International Journal of Antimicrobial Agents |
| McLeod S, Shapiro A, Moussa S, et al. (2016) Sulbactam Combined With the Novel β-lactamase Inhibitor ETX2514 for the Treatment of Multidrug-Resistant Acinetobacter baumannii Infections Open Forum Infectious Diseases. 3 |
| Nayar AS, Dougherty TJ, Ferguson KE, et al. (2015) Novel antibacterial targets and compounds revealed by a high-throughput cell wall reporter assay. Journal of Bacteriology. 197: 1726-34 |
| McLeod SM, Fleming PR, MacCormack K, et al. (2015) Small-molecule inhibitors of gram-negative lipoprotein trafficking discovered by phenotypic screening. Journal of Bacteriology. 197: 1075-82 |