Parents

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Frank H. Westheimer grad student 1968 Harvard
 (A model for the role of metal-ions in the enzyme-catalyzed hydrolysis of polyphosphates.)

Children

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Christian Hamann grad student Penn
Rebecca W. Alexander grad student 1996 Penn
Bari A. Pender grad student 2000 Penn
Ossama B. Kashlan grad student 2002 Penn
Zhanna Druzina grad student 2003 Penn
Hyuk-Soo Seo grad student 2004 Penn
Stacey Lavender grad student 2007 Penn
Dongli Pan grad student 2007 Penn
Gunes E. Atilla Gokcumen grad student 2008 Penn
Hanqing Liu grad student 2010 Penn
Haiou Qin grad student 2010 Penn
Ian S. Farrell grad student 2011 Penn
Yuanwei Chen grad student 2008-2015 Penn
Pradipta Purkayastha post-doc 2002-2004 Penn
Monika Raj post-doc 2010-2010 Penn
BETA: Related publications

Publications

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Ghelfi MD, Bhat SY, Li H, et al. (2023) A High-Throughput Assay for In Vitro Determination of Release Factor-Dependent Peptide Release from a Pretermination Complex by Fluorescence Anisotropy-Application to Nonsense Suppressor Screening and Mechanistic Studies. Biomolecules. 13
Avolio R, Agliarulo I, Criscuolo D, et al. (2023) Cytosolic and mitochondrial translation elongation are coordinated through the molecular chaperone TRAP1 for the synthesis and import of mitochondrial proteins. Biorxiv : the Preprint Server For Biology
Remes C, Khawaja A, Pearce SF, et al. (2023) Translation initiation of leaderless and polycistronic transcripts in mammalian mitochondria. Nucleic Acids Research. 51: 891-907
Krüger A, Remes C, Shiriaev DI, et al. (2023) Human mitochondria require mtRF1 for translation termination at non-canonical stop codons. Nature Communications. 14: 30
Huang S, Bhattacharya A, Ghelfi MD, et al. (2022) Ataluren binds to multiple protein synthesis apparatus sites and competitively inhibits release factor-dependent termination. Nature Communications. 13: 2413
Cooperman BS. (2021) Site-Specific Fluorescent Labeling of RNA Interior Positions. Molecules (Basel, Switzerland). 26
Ng MY, Li H, Ghelfi MD, et al. (2021) Ataluren and aminoglycosides stimulate read-through of nonsense codons by orthogonal mechanisms. Proceedings of the National Academy of Sciences of the United States of America. 118
Ng MY, Zhang H, Weil A, et al. (2018) New Assay Measuring Direct Interaction of Nonsense Suppressors with the Eukaryotic Protein Synthesis Machinery. Acs Medicinal Chemistry Letters. 9: 1285-1291
Dhakal R, Tong C, Anderson S, et al. (2018) Dynamics of intracellular stress-induced tRNA trafficking. Nucleic Acids Research
Johansen JS, Kavaliauskas D, Pfeil SH, et al. (2018) E. coli elongation factor Tu bound to a GTP analogue displays an open conformation equivalent to the GDP-bound form. Nucleic Acids Research
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