John J. Mekalanos
Affiliations: | Microbiology and Immunobiology | Harvard University, Cambridge, MA, United States |
Area:
biochemical and genetic analysis of bacterial virulence factorsWebsite:
http://mbib.med.harvard.edu/faculty/mekalanos.htmlGoogle:
"John Joseph Mekalanos"Bio:
Parents
Sign in to add mentor| R. John Collier | grad student | 1978 | UCLA (Chemistry Tree) | |
| (Genetic and biochemical studies of cholera toxin.) | ||||
Children
Sign in to add trainee| Virginia Miller | grad student | Harvard Medical School | |
| Karen M. Ottemann | grad student | ||
| Kenneth M. Peterson | grad student | Harvard Medical School | |
| Ronald K. Taylor | grad student | Darthmouth | |
| Karl E. Klose | grad student | 1992-1996 | Harvard Medical School |
| Nicholas M. Judson | grad student | 2002 | Harvard |
| James Bina | grad student | 1998-2003 | University of Pittsburgh School of Medicine |
| Stefan Pukatzki | grad student | 1999-2006 | The City College of New York |
| Elizabeth A. Shakhnovich | grad student | 2007 | Harvard |
| Vincent C. Tam | grad student | 2008 | Harvard |
| Douglas E. Cameron | grad student | 2009 | Harvard |
| Brian T. Ho | grad student | 2014 | Harvard |
| Victor J. DiRita | post-doc | Harvard | |
| Deborah T. Hung | post-doc | ||
| Eric J. Rubin | post-doc | Harvard | |
| James M. Slauch | post-doc | ||
| Russell E. Vance | post-doc | Harvard Medical School (ID Tree) | |
| Fabian Rivera-Chávez | post-doc | 2016- | Harvard Medical School (Evolution Tree) |
| Daniele Provenzano | post-doc | 2001-2002 | Harvard Medical School |
| Olga Danilchanka | post-doc | 2012-2015 |
BETA: Related publications
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Publications
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| Pons S, Frapy E, Sereme Y, et al. (2023) A high-throughput sequencing approach identifies immunotherapeutic targets for bacterial meningitis in neonates. Ebiomedicine. 88: 104439 |
| Rivera-Chávez F, Meader BT, Akosman S, et al. (2022) A Potent Inhibitor of the Cystic Fibrosis Transmembrane Conductance Regulator Blocks Disease and Morbidity Due to Toxigenic . Toxins. 14 |
| Manera K, Caro F, Li H, et al. (2021) Sensing of intracellular Hcp levels controls T6SS expression in . Proceedings of the National Academy of Sciences of the United States of America. 118 |
| Caro F, Caro JA, Place NM, et al. (2020) Transcriptional Silencing by TsrA in the Evolution of Pathogenic Vibrio cholerae Biotypes. Mbio. 11 |
| Lowey B, Whiteley AT, Keszei AFA, et al. (2020) CBASS Immunity Uses CARF-Related Effectors to Sense 3'-5'- and 2'-5'-Linked Cyclic Oligonucleotide Signals and Protect Bacteria from Phage Infection. Cell |
| Lau RK, Ye Q, Birkholz EA, et al. (2020) Structure and Mechanism of a Cyclic Trinucleotide-Activated Bacterial Endonuclease Mediating Bacteriophage Immunity. Molecular Cell |
| Liang X, Kamal F, Pei TT, et al. (2019) An onboard checking mechanism ensures effector delivery of the type VI secretion system in . Proceedings of the National Academy of Sciences of the United States of America |
| Pincus NB, Bachta KER, Ozer EA, et al. (2019) Long-term Persistence of an Extensively Drug Resistant Subclade of Globally Distributed Pseudomonas aeruginosa Clonal Complex 446 in an Academic Medical Center. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America |
| Caro F, Place NM, Mekalanos JJ. (2019) Analysis of lipoprotein transport depletion in using CRISPRi. Proceedings of the National Academy of Sciences of the United States of America |
| Rivera-Chávez F, Mekalanos JJ. (2019) Cholera toxin promotes pathogen acquisition of host-derived nutrients. Nature. 572: 244-248 |