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Virginia A. Zakian

Affiliations: 
Molecular Biology Princeton University, Princeton, NJ 
Website:
http://www.molbio1.princeton.edu/labs/zakian/
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"Virginia Zakian"
Bio:

http://www.molbio1.princeton.edu/labs/zakian/2004_zakian_cv.htm
http://molbio.princeton.edu/labs/images/zakian/documents/CvCurrent_shortened_3_15.pdf

Cross-listing: Chemistry Tree

Parents

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Joseph G. Gall grad student 1975 Yale
 (Electron Microscopic Studies of DNA Replication in Drosophila Virilis)
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Publications

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Lee RS, Geronimo CL, Liu L, et al. (2023) Identification of the nuclear localization signal in the Saccharomyces cerevisiae Pif1 DNA helicase. Plos Genetics. 19: e1010853
Zhou ZX, Follonier C, Lujan SA, et al. (2023) Pif1 family helicases promote mutation avoidance during DNA replication. Nucleic Acids Research. 50: 12844-12855
Garcia PD, Zakian VA. (2020) A new role for proteins subunits of RNase P: stabilization of the telomerase holoenzyme. Microbial Cell (Graz, Austria). 7: 250-254
Garcia PD, Leach RW, Wadsworth GM, et al. (2020) Stability and nuclear localization of yeast telomerase depend on protein components of RNase P/MRP. Nature Communications. 11: 2173
Chen CF, Pohl TJ, Chan A, et al. (2019) Centromere RNA Is Negatively Regulated by Cbf1 and Its Unscheduled Synthesis Impacts CenH3 Binding. Genetics
Pohl TJ, Zakian VA. (2019) Pif1 family DNA helicases: A helpmate to RNase H? Dna Repair
Chen CF, Pohl TJ, Pott S, et al. (2018) Two Pif1-family DNA Helicases Cooperate in Centromere Replication and Segregation in . Genetics
Geronimo CL, Singh SP, Galletto R, et al. (2018) The signature motif of the Saccharomyces cerevisiae Pif1 DNA helicase is essential in vivo for mitochondrial and nuclear functions and in vitro for ATPase activity. Nucleic Acids Research. 46: 8357-8370
Tran PLT, Pohl TJ, Chen CF, et al. (2017) PIF1 family DNA helicases suppress R-loop mediated genome instability at tRNA genes. Nature Communications. 8: 15025
McDonald KR, Guise AJ, Pourbozorgi-Langroudi P, et al. (2016) Pfh1 Is an Accessory Replicative Helicase that Interacts with the Replisome to Facilitate Fork Progression and Preserve Genome Integrity. Plos Genetics. 12: e1006238
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