Kannan R. Karukurichi, Ph.D.
Affiliations: | 2006 | The University of Nebraska - Lincoln, Lincoln, NE |
Area:
Organic Chemistry, BiochemistryGoogle:
"Kannan Karukurichi"Mean distance: 7238.73
Parents
Sign in to add mentor| David B. Berkowitz | grad student | 2006 | University of Nebraska - Lincoln | |
| (I. A new suicide trigger for L-lysine decarboxylase. II. Second generation in situ enzymatic screening (ISES): Predicting enantioselectivity.) | ||||
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Publications
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| Michaelides MR, Kluge A, Patane M, et al. (2018) Discovery of Spiro Oxazolidinediones as Selective, Orally Bioavailable Inhibitors of p300/CBP Histone Acetyltransferases. Acs Medicinal Chemistry Letters. 9: 28-33 |
| Lasko LM, Jakob CG, Edalji RP, et al. (2017) Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours. Nature |
| Karukurichi KR, Fei X, Swyka RA, et al. (2015) Mini-ISES identifies promising carbafructopyranose-based salens for asymmetric catalysis: Tuning ligand shape via the anomeric effect. Science Advances. 1 |
| Wang Y, Kavran JM, Chen Z, et al. (2014) Regulation of S-adenosylhomocysteine hydrolase by lysine acetylation. The Journal of Biological Chemistry. 289: 31361-72 |
| Karukurichi KR, Cole PA. (2011) Probing the reaction coordinate of the p300/CBP histone acetyltransferase with bisubstrate analogs. Bioorganic Chemistry. 39: 42-7 |
| Karukurichi KR, Wang L, Uzasci L, et al. (2010) Analysis of p300/CBP histone acetyltransferase regulation using circular permutation and semisynthesis. Journal of the American Chemical Society. 132: 1222-3 |
| Berkowitz DB, Karukurichi KR, De La Salud-Bea R, et al. (2009) Stereoselective synthesis of quaternary, α-vinyl amino acids and their α-(2'Z-fluoro)vinyl congeners: Promising candidates for PLP enzyme inactivation Acs Symposium Series. 1009: 288-303 |
| Berkowitz DB, Karukurichi KR, de la Salud-Bea R, et al. (2008) Use of Fluorinated Functionality in Enzyme Inhibitor Development: Mechanistic and Analytical Advantages. Journal of Fluorine Chemistry. 129: 731-742 |
| Karukurichi KR, de la Salud-Bea R, Jahng WJ, et al. (2007) Examination of the new alpha-(2'Z-fluoro)vinyl trigger with lysine decarboxylase: the absolute stereochemistry dictates the reaction course. Journal of the American Chemical Society. 129: 258-9 |
| Berkowitz DB, Charette BD, Karukurichi KR, et al. (2006) α-Vinylic Amino Acids: Occurrence, Asymmetric Synthesis and Biochemical Mechanisms. Tetrahedron, Asymmetry. 17: 869-882 |