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Lewis C. Cantley, Ph.D.

Systems Biology Harvard University, Cambridge, MA, United States 
PI3K and cancer metabolism
"Lewis C. Cantley"

Cross-listing: Chemistry Tree - Cell Biology Tree


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Gordon G. Hammes grad student 1975 Cornell (Chemistry Tree)
 (Characterization of effector binding sites on the coupling factors of oxidative phosphorylation and photophosphorylation)
Guido Guidotti post-doc 1978 Harvard (Chemistry Tree)


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Daniel Avery Pollard research assistant 1998-2001 Harvard Medical School
Seth J. Field grad student (Cell Biology Tree)
Bryan Ngo grad student Weil Cornell Medical College (Chemistry Tree)
Claudine M. Yballe grad student 2000 Harvard (Chemistry Tree)
Katja A. Lamia grad student 2003 Harvard (Chemistry Tree)
Andrew E. Elia grad student 2005 Harvard (Chemistry Tree)
Ji Luo grad student 2006 Harvard (Chemistry Tree)
Tina L. Yuan grad student 2010 Harvard (Chemistry Tree)
Cynthia V. Clower grad student 2011 Harvard (Chemistry Tree)
Peiling Tsou grad student 2011 Harvard (Chemistry Tree)
Shyh C. Ng grad student 2013 Harvard (Chemistry Tree)
Kevin D. Courtney post-doc Dana-Farber Cancer Institute (Neurotree)
Alex Toker post-doc (Cell Biology Tree)
Benjamin Turk post-doc Harvard Medical School (Chemistry Tree)
Matthew G. Vander Heiden post-doc Harvard Medical School (Chemistry Tree)
Orion D. Weiner post-doc (Neurotree)
Jihye Yun post-doc Weill Cornell Medical College (Chemistry Tree)
Michael B. Yaffe post-doc 1996-1998 Harvard Medical School (Chemistry Tree)
Bin Zheng post-doc 2003-2010 (Neurotree)
Jason W. Locasale post-doc 2008-2012 Harvard Medical School, Boston, USA (Cell Biology Tree)
Gina M DeNicola post-doc 2010-2015 Harvard Medical School - Beth Israel Deaconess Medical Center (Chemistry Tree)
Costas Lyssiotis post-doc 2010-2015 Harvard Medical School (Chemistry Tree)
Marcus DaSilva Goncalves post-doc 2014-2018 Weill Cornell Medicine (Neurotree)
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Yaron-Barir TM, Joughin BA, Huntsman EM, et al. (2024) The intrinsic substrate specificity of the human tyrosine kinome. Nature
Rogava M, Aprati TJ, Chi WY, et al. (2024) Loss of Pip4k2c confers liver-metastatic organotropism through insulin-dependent PI3K-AKT pathway activation. Nature Cancer
Lin TY, Ramsamooj S, Perrier T, et al. (2023) Epinephrine inhibits PI3Kα via the Hippo kinases. Cell Reports. 42: 113535
Ferrarone JR, Thomas J, Unni AM, et al. (2023) LKB1 suppresses growth and promotes the internalization of EGFR through the PIKFYVE lipid kinase. Biorxiv : the Preprint Server For Biology
Darabedian N, Ji W, Fan M, et al. (2023) Depletion of creatine phosphagen energetics with a covalent creatine kinase inhibitor. Nature Chemical Biology
Stein BD, Ferrarone JR, Gardner EE, et al. (2023) LKB1-dependent regulation of TPI1 creates a divergent metabolic liability between human and mouse lung adenocarcinoma. Cancer Discovery
Johnson JL, Yaron TM, Huntsman EM, et al. (2023) An atlas of substrate specificities for the human serine/threonine kinome. Nature
Langer HT, Cantley LC, Goncalves MD. (2022) Live cold to grow old? Thermogenesis to fight cancer. Cell Research
Queiroz AL, Dantas E, Ramsamooj S, et al. (2022) Blocking ActRIIB and restoring appetite reverses cachexia and improves survival in mice with lung cancer. Nature Communications. 13: 4633
Dibble CC, Barritt SA, Perry GE, et al. (2022) PI3K drives the de novo synthesis of coenzyme A from vitamin B5. Nature
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