Lewis C. Cantley, Ph.D.
Affiliations: | Systems Biology | Harvard University, Cambridge, MA, United States |
Area:
PI3K and cancer metabolismWebsite:
http://www.fas.harvard.edu/~biophys/Lewis_Cantley.htmGoogle:
"Lewis C. Cantley"Bio:
http://sysbio.med.harvard.edu/faculty/cantley/
http://cantley.hms.harvard.edu/
http://www.pnas.org/content/101/10/3327.full
Cross-listing: Chemistry Tree - Cell Biology Tree
Parents
Sign in to add mentor| Gordon G. Hammes | grad student | 1975 | Cornell (Chemistry Tree) | |
| (Characterization of effector binding sites on the coupling factors of oxidative phosphorylation and photophosphorylation) | ||||
| Guido Guidotti | post-doc | 1978 | Harvard (Chemistry Tree) | |
Children
Sign in to add trainee| Daniel Avery Pollard | research assistant | 1998-2001 | Harvard Medical School |
| Seth J. Field | grad student | (Cell Biology Tree) | |
| Bryan Ngo | grad student | Weil Cornell Medical College (Chemistry Tree) | |
| Claudine M. Yballe | grad student | 2000 | Harvard (Chemistry Tree) |
| Katja A. Lamia | grad student | 2003 | Harvard (Chemistry Tree) |
| Andrew E. Elia | grad student | 2005 | Harvard (Chemistry Tree) |
| Ji Luo | grad student | 2006 | Harvard (Chemistry Tree) |
| Tina L. Yuan | grad student | 2010 | Harvard (Chemistry Tree) |
| Cynthia V. Clower | grad student | 2011 | Harvard (Chemistry Tree) |
| Peiling Tsou | grad student | 2011 | Harvard (Chemistry Tree) |
| Shyh C. Ng | grad student | 2013 | Harvard (Chemistry Tree) |
| Kevin D. Courtney | post-doc | Dana-Farber Cancer Institute (Neurotree) | |
| Alex Toker | post-doc | (Cell Biology Tree) | |
| Benjamin Turk | post-doc | Harvard Medical School (Chemistry Tree) | |
| Matthew G. Vander Heiden | post-doc | Harvard Medical School (Chemistry Tree) | |
| Jihye Yun | post-doc | Weill Cornell Medical College (Chemistry Tree) | |
| Michael B. Yaffe | post-doc | 1996-1998 | Harvard Medical School (Chemistry Tree) |
| Jason W. Locasale | post-doc | 2008-2012 | Harvard Medical School, Boston, USA (Cell Biology Tree) |
| Gina M DeNicola | post-doc | 2010-2015 | Harvard Medical School - Beth Israel Deaconess Medical Center (Chemistry Tree) |
| Costas Lyssiotis | post-doc | 2010-2015 | Harvard Medical School (Chemistry Tree) |
| Marcus DaSilva Goncalves | post-doc | 2014-2018 | Weill Cornell Medicine (Neurotree) |
BETA: Related publications
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Publications
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| Darabedian N, Ji W, Fan M, et al. (2023) Depletion of creatine phosphagen energetics with a covalent creatine kinase inhibitor. Nature Chemical Biology |
| Stein BD, Ferrarone JR, Gardner EE, et al. (2023) LKB1-dependent regulation of TPI1 creates a divergent metabolic liability between human and mouse lung adenocarcinoma. Cancer Discovery |
| Johnson JL, Yaron TM, Huntsman EM, et al. (2023) An atlas of substrate specificities for the human serine/threonine kinome. Nature |
| Langer HT, Cantley LC, Goncalves MD. (2022) Live cold to grow old? Thermogenesis to fight cancer. Cell Research |
| Queiroz AL, Dantas E, Ramsamooj S, et al. (2022) Blocking ActRIIB and restoring appetite reverses cachexia and improves survival in mice with lung cancer. Nature Communications. 13: 4633 |
| Dibble CC, Barritt SA, Perry GE, et al. (2022) PI3K drives the de novo synthesis of coenzyme A from vitamin B5. Nature |
| Yoshida T, Kawabe T, Cantley LC, et al. (2022) Discovery and Characterization of a Novel Allosteric Small-Molecule Inhibitor of NADP-Dependent Malic Enzyme 1. Biochemistry. 61: 1548-1553 |
| Taylor SR, Falcone JN, Cantley LC, et al. (2022) Developing dietary interventions as therapy for cancer. Nature Reviews. Cancer |
| Davdison SM, Schmidt DR, Heyman JE, et al. (2022) Pyruvate kinase M1 suppresses development and progression of prostate adenocarcinoma. Cancer Research |
| Gomes AP, Ilter D, Low V, et al. (2022) Altered propionate metabolism contributes to tumour progression and aggressiveness. Nature Metabolism |