Jinshui Fan, Ph.D.

2002 Dalhousie University, Halifax, Nova Scotia, Canada 
Plant Physiology, Molecular Biology
"Jinshui Fan"


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Robert W. Lee grad student 2002 Dalhousie University
 (Characterization of the mitochondrial genome and ribosomal RNAs of the colorless green alga Polytomella parva.)
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Fan J, Robert C, Jang YY, et al. (2011) Human induced pluripotent cells resemble embryonic stem cells demonstrating enhanced levels of DNA repair and efficacy of nonhomologous end-joining. Mutation Research. 713: 8-17
Li L, Zhang L, Fan J, et al. (2011) Defective nonhomologous end joining blocks B-cell development in FLT3/ITD mice. Blood. 117: 3131-9
Fan J, Li L, Small D, et al. (2010) Cells expressing FLT3/ITD mutations exhibit elevated repair errors generated through alternative NHEJ pathways: implications for genomic instability and therapy. Blood. 116: 5298-305
Berquist BR, Singh DK, Fan J, et al. (2010) Functional capacity of XRCC1 protein variants identified in DNA repair-deficient Chinese hamster ovary cell lines and the human population. Nucleic Acids Research. 38: 5023-35
Cheadle C, Watkins T, Fan J, et al. (2009) GSMA: Gene Set Matrix Analysis, An Automated Method for Rapid Hypothesis Testing of Gene Expression Data. Bioinformatics and Biology Insights. 1: 49-62
Fan J, Li L, Small D, et al. (2009) Cell Lines and “Knock-in” Mice Bearing FLT3/ITD Mutations Exhibit Elevated Repair Errors Generated through Alternative DNA Double Strand Break Repair Pathways: Implications for Genomic Instability. Blood. 114: 3237-3237
Li L, Zhang L, Fan J, et al. (2009) B-Lymphocyte Development Is Impaired by FLT3/ITD Signaling in Knock-in Mice Because of Defective Non-Homologous End-Joining. Blood. 114: 184-184
Sallmyr A, Fan J, Rassool FV. (2008) Genomic instability in myeloid malignancies: increased reactive oxygen species (ROS), DNA double strand breaks (DSBs) and error-prone repair. Cancer Letters. 270: 1-9
Sallmyr A, Fan J, Datta K, et al. (2008) Internal tandem duplication of FLT3 (FLT3/ITD) induces increased ROS production, DNA damage, and misrepair: implications for poor prognosis in AML. Blood. 111: 3173-82
Fan J, Wilson PF, Wong HK, et al. (2007) XRCC1 down-regulation in human cells leads to DNA-damaging agent hypersensitivity, elevated sister chromatid exchange, and reduced survival of BRCA2 mutant cells. Environmental and Molecular Mutagenesis. 48: 491-500
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