Joseph W. Thornton, Ph.D.
Affiliations: | 2002-2014 | University of Oregon, Eugene, OR, United States | |
| 2012- | University of Chicago, Chicago, IL |
Area:
protein evolutionWebsite:
https://genes.uchicago.edu/admin/person/joe-thornton-phdGoogle:
"Joseph Thornton"Parents
Sign in to add mentor| Rob DeSalle | grad student | American Museum of Natural History | ||
| Darcy B. Kelley | grad student | 2000 | Columbia (Neurotree) | |
| (The evolution of molecular novelty: Mechanisms for generating and selecting new proteins and functions in the nuclear receptor superfamily.) | ||||
Children
Sign in to add trainee| Victor Hanson-Smith | grad student | University of Oregon | |
| Bryan Kolaczkowski | grad student | 2006 | University of Oregon |
| Sean M. Carroll | grad student | 2009 | University of Oregon |
| Michael Harms | post-doc | University of Oregon | |
| Carrie F. Olson-Manning | post-doc | 2013-2016 | Chicago (Chemistry Tree) |
| Lora K. Picton | research scientist | 2013-2016 | Chicago (Chemistry Tree) |
BETA: Related publications
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Publications
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| Metzger BPH, Park Y, Starr TN, et al. (2024) Epistasis facilitates functional evolution in an ancient transcription factor. Elife. 12 |
| Park Y, Metzger BPH, Thornton JW. (2023) The simplicity of protein sequence-function relationships. Biorxiv : the Preprint Server For Biology |
| Pillai AS, Hochberg GKA, Thornton JW. (2022) Simple mechanisms for the evolution of protein complexity. Protein Science : a Publication of the Protein Society. e4449 |
| Park Y, Metzger BPH, Thornton JW. (2022) Epistatic drift causes gradual decay of predictability in protein evolution. Science (New York, N.Y.). 376: 823-830 |
| Xie VC, Pu J, Metzger BP, et al. (2021) Contingency and chance erase necessity in the experimental evolution of ancestral proteins. Elife. 10 |
| Hochberg GKA, Liu Y, Marklund EG, et al. (2020) A hydrophobic ratchet entrenches molecular complexes. Nature |
| Pillai AS, Chandler SA, Liu Y, et al. (2020) Origin of complexity in haemoglobin evolution. Nature. 581: 480-485 |
| Siddiq MA, Thornton JW. (2019) Fitness effects but no temperature-mediated balancing selection at the polymorphic gene of . Proceedings of the National Academy of Sciences of the United States of America |
| Cheng S, Park Y, Kurleto JD, et al. (2019) Family of neural wiring receptors in bilaterians defined by phylogenetic, biochemical, and structural evidence. Proceedings of the National Academy of Sciences of the United States of America |
| Liu Q, Onal P, Datta RR, et al. (2018) Ancient mechanisms for the evolution of the bicoid homeodomain's function in fly development. Elife. 7 |