Marvin W. Makinen
Affiliations: | Biochemistry & Molecular Biophysics | University of Chicago, Chicago, IL |
Area:
structural basis of enzyme action through a detailed correlation of the electronic structure, stereochemistry, and molecular structure of enzyme-substrate complexesWebsite:
http://bmb.uchospitals.edu/Faculty_and_Research/01_Faculty/01_Faculty_Alphabetically.php?faculty_id=99Google:
"Marvin W. Makinen"Mean distance: 9.26 | S | N | B | C | P |
Children
Sign in to add trainee| Martin P. Horvath | grad student | 1994 | Chicago |
| Victor W. Huang | grad student | 2003 | Chicago |
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Publications
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| Mustafi D, Makinen MW. (2005) Structure and conformation of bis(acetylacetonato)oxovanadium(IV) and bis(maltolato)oxovanadium(IV) in solution determined by electron nuclear double resonance spectroscopy. Inorganic Chemistry. 44: 5580-90 |
| Mustafi D, Hofer JE, Huang W, et al. (2004) Chromophoric spin-labeled beta-lactam antibiotics for ENDOR structural characterization of reaction intermediates of class A and class C beta-lactamases. Spectrochimica Acta. Part a, Molecular and Biomolecular Spectroscopy. 60: 1279-89 |
| Mustafi D, Bekesi A, Vertessy BG, et al. (2003) Catalytic and structural role of the metal ion in dUTP pyrophosphatase. Proceedings of the National Academy of Sciences of the United States of America. 100: 5670-5 |
| Mustafi D, Sosa-Peinado A, Gupta V, et al. (2002) Structure of spin-labeled methylmethanethiolsulfonate in solution and bound to TEM-1 beta-lactamase determined by electron nuclear double resonance spectroscopy. Biochemistry. 41: 797-808 |
| Mustafi D, Sosa-Peinado A, Makinen MW. (2001) ENDOR structural characterization of a catalytically competent acylenzyme reaction intermediate of wild-type TEM-1 beta-lactamase confirms glutamate-166 as the base catalyst. Biochemistry. 40: 2397-409 |
| Van Zele CJ, Cunningham MA, Makinen MW. (2001) Validation of nitroxyl spin-label force-field parameters through molecular dynamics simulations Journal of Computational Chemistry. 22: 1113-1123 |
| Sosa-Peinado A, Mustafi D, Makinen MW. (2000) Overexpression and biosynthetic deuterium enrichment of TEM-1 beta-lactamase for structural characterization by magnetic resonance methods. Protein Expression and Purification. 19: 235-45 |
| Atanasov BP, Mustafi D, Makinen MW. (2000) Protonation of the beta-lactam nitrogen is the trigger event in the catalytic action of class A beta-lactamases. Proceedings of the National Academy of Sciences of the United States of America. 97: 3160-5 |
| Horvath MP, Copeland RA, Makinen MW. (1999) The second derivative electronic absorption spectrum of cytochrome c oxidase in the Soret region. Biophysical Journal. 77: 1694-711 |
| Makinen MW. (1998) Electron nuclear double resonance determined structures of enzyme reaction intermediates: structural evidence for substrate destabilization. Spectrochimica Acta. Part a, Molecular and Biomolecular Spectroscopy. 54: 2269-81 |