Laurence Hurst, Ph.D

Biology and Biochemistry Bath 
Genetics, Genomics
"Laurence Hurst"
Cross-listing: Chemistry Tree

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Hurst LD, Batada NN. (2017) Depletion of somatic mutations in splicing-associated sequences in cancer genomes. Genome Biology. 18: 213
Hurst LD, Ghanbarian AT, Forrest AR, et al. (2015) The Constrained Maximal Expression Level Owing to Haploidy Shapes Gene Content on the Mammalian X Chromosome. Plos Biology. 13: e1002315
Yang S, Wang L, Huang J, et al. (2015) Parent-progeny sequencing indicates higher mutation rates in heterozygotes. Nature
Wu X, Hurst LD. (2015) Why Selection Might Be Stronger When Populations Are Small: Intron Size and Density Predict within and between-Species Usage of Exonic Splice Associated cis-Motifs. Molecular Biology and Evolution. 32: 1847-61
Ghanbarian AT, Hurst LD. (2015) Neighboring Genes Show Correlated Evolution in Gene Expression. Molecular Biology and Evolution. 32: 1748-66
Liu H, Zhang X, Huang J, et al. (2015) Causes and consequences of crossing-over evidenced via a high-resolution recombinational landscape of the honey bee. Genome Biology. 16: 15
Sealey KL, Harris SR, Fry NK, et al. (2015) Genomic Analysis of Isolates From the United Kingdom 2012 Pertussis Outbreak Reveals That Vaccine Antigen Genes Are Unusually Fast Evolving. The Journal of Infectious Diseases. 212: 294-301
Wang J, Xie G, Singh M, et al. (2014) Primate-specific endogenous retrovirus-driven transcription defines naive-like stem cells. Nature. 516: 405-9
Jiang C, Mithani A, Belfield EJ, et al. (2014) Environmentally responsive genome-wide accumulation of de novo Arabidopsis thaliana mutations and epimutations. Genome Research. 24: 1821-9
Schüler A, Ghanbarian AT, Hurst LD. (2014) Purifying selection on splice-related motifs, not expression level nor RNA folding, explains nearly all constraint on human lincRNAs. Molecular Biology and Evolution. 31: 3164-83
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