Johan-Owen De Craene, Ph. D.

2016- Biomolécules et Biotechnologies Végétales Universite de Tours 
yeast synthetic biology and evolution
"Johan-Owen De Craene"

I graduated as a Chemistry major from the ULB in 1995. I got my PhD in 2001 after studying the regulation of the yeast amino acid transporter Gap1 in Bruno Andre's lab.
My first postdoc was in Peter Novick's lab at Yale University between 2002 and 2006 where I studied ER inheritance and tubulation.
I'm currently at the University of Strasbourg where I'm studying the role of PI3P in genetic diseases and aa metabolism first in Sylvie Friant's lab and now in Hubert Becker's.


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Bruno André grad student 1995-2001 ULB
Bruno André post-doc 2001-2002 ULB
Peter Novick post-doc 2002-2006 Yale School of Medicine (Cell Biology Tree)
Sylvie Friant post-doc 2006-2014 Université de Strasbourg
Hubert Becker post-doc 2015-2016 Université de Strasbourg
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Enkler L, Rinaldi B, de Craene JO, et al. (2021) Cex1 is a component of the COPI intracellular trafficking machinery. Biology Open. 10
Bader G, Enkler L, Araiso Y, et al. (2020) Assigning mitochondrial localization of dual localized proteins using a yeast Bi-Genomic Mitochondrial-Split-GFP. Elife. 9
De Craene JO, Bertazzi DL, Bär S, et al. (2017) Phosphoinositides, Major Actors in Membrane Trafficking and Lipid Signaling Pathways. Int J Mol Sci.. 18: e634
Stoetzel C, Bär S, De Craene JO, et al. (2016) A mutation in VPS15 (PIK3R4) causes a ciliopathy and affects IFT20 release from the cis-Golgi. Nature Communications. 7: 13586
Debard S, Bader G, De Craene JO, et al. (2016) Nonconventional localizations of cytosolic aminoacyl-tRNA synthetases in yeast and human cells. Methods. 113: 91/104
Bertazzi DL, De Craene JO, Bär S, et al. (2015) Phosphoinositides: lipidic essential actors in the intracellular traffic Biologie Aujourd'Hui. 209: 97-109
Feyder S, De Craene JO, Bär S, et al. (2015) Membrane trafficking in the yeast Saccharomyces cerevisiae model. Int J Mol Sci.. 16: 1509-1525
Morvan J, de Craene JO, Rinaldi B, et al. (2015) Btn3 regulates the endosomal sorting function of the yeast Ent3 epsin, an adaptor for SNARE proteins. Journal of Cell Science. 128: 706-16
De Craene JO, Courte F, Rinaldi B, et al. (2014) Study of the plant COPII vesicle coat subunits by functional complementation of yeast Saccharomyces cerevisiae mutants. Plos One. 9: e90072
Bertazzi DL, De Craene JO, Friant S. (2014) Myotubularin MTM1 Involved in Centronuclear Myopathy and its Roles in Human and Yeast Cells Journal of Molecular and Genetic Medicine. 8: 1000116
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