Alan P. Wolffe
Affiliations: | National Institutes of Health, Bethesda, MD |
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Parents
Sign in to add mentor| Jamshed R. Tata | grad student | National Institute for Medical Research, London (Cell Biology Tree) | |
| Donald D. Brown | post-doc | NIH |
Children
Sign in to add trainee| Genevieve Almouzni | post-doc | NIH (NICHD) (Cell Biology Tree) | |
| Jeffrey J Hayes | post-doc | (Evolution Tree) |
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Publications
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| Wolffe AP. (2005) Activating chromatin. Current Biology : Cb. 1: 366-8 |
| Wolffe AP. (2004) Developmental regulation of chromatin structure and function. Trends in Cell Biology. 1: 61-6 |
| Jouvenot Y, Ginjala V, Zhang L, et al. (2003) Targeted regulation of imprinted genes by synthetic zinc-finger transcription factors. Gene Therapy. 10: 513-22 |
| Rebar EJ, Huang Y, Hickey R, et al. (2002) Induction of angiogenesis in a mouse model using engineered transcription factors. Nature Medicine. 8: 1427-32 |
| El-Osta A, Baker EK, Wolffe AP. (2002) Profiling methyl-CpG specific determinants on transcriptionally silent chromatin. Molecular Biology Reports. 28: 209-15 |
| Mutskov VJ, Farrell CM, Wade PA, et al. (2002) The barrier function of an insulator couples high histone acetylation levels with specific protection of promoter DNA from methylation. Genes & Development. 16: 1540-54 |
| Jones PL, Wade PA, Wolffe AP. (2002) Purification of MeCP2-containing deacetylase from Xenopus laevis. Methods in Molecular Biology (Clifton, N.J.). 200: 131-41 |
| El-Osta A, Kantharidis P, Zalcberg JR, et al. (2002) Precipitous release of methyl-CpG binding protein 2 and histone deacetylase 1 from the methylated human multidrug resistance gene (MDR1) on activation. Molecular and Cellular Biology. 22: 1844-57 |
| Wolffe AP. (2002) Transcriptional regulation in the context of chromatin structure. Essays in Biochemistry. 37: 45-57 |
| Jones PL, Wade PA, Wolffe AP. (2001) Purification of the MeCP2/histone deacetylase complex from Xenopus laevis. Methods in Molecular Biology (Clifton, N.J.). 181: 297-307 |