Isaac Canals

Affiliations: 
Department of Genetics, Microbiology and Statistics Universitat de Barcelona, Barcelona, Cataluña, Spain 
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"Isaac Canals"
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Canals I, Comella-Bolla A, Cepeda-Prado E, et al. (2023) Astrocyte dysfunction and neuronal network hyperactivity in a CRISPR engineered pluripotent stem cell model of frontotemporal dementia. Brain Communications. 5: fcad158
Trovato F, Stefani FR, Li J, et al. (2022) Transcription Factor Forced Astrocytic Differentiation Impairs Human Glioblastoma Growth In Vitro and In Vivo. Molecular Cancer Therapeutics
Quist E, Trovato F, Avaliani N, et al. (2022) Transcription factor-based direct conversion of human fibroblasts to functional astrocytes. Stem Cell Reports
Canals I, Quist E, Ahlenius H. (2021) Transcription Factor-Based Strategies to Generate Neural Cell Types from Human Pluripotent Stem Cells. Cellular Reprogramming. 23: 206-220
Canals I, Ahlenius H. (2021) CRISPR/Cas9 Genome Engineering in Human Pluripotent Stem Cells for Modeling of Neurological Disorders. Methods in Molecular Biology (Clifton, N.J.). 2352: 237-251
Quist E, Ahlenius H, Canals I. (2021) Transcription Factor Programming of Human Pluripotent Stem Cells to Functionally Mature Astrocytes for Monocultures and Cocultures with Neurons. Methods in Molecular Biology (Clifton, N.J.). 2352: 133-148
Benetó N, Grinberg D, Vilageliu L, et al. (2021) Genome Editing Using Cas9-gRNA Ribonucleoprotein in Human Pluripotent Stem Cells for Disease Modeling. Methods in Molecular Biology (Clifton, N.J.)
Tolomeo AM, Laterza C, Grespan E, et al. (2021) mmRNA-Based Transcriptional Programming in Microfluidic Guides hiPSCs Toward Neural Fate With Multiple Identities. Frontiers in Cellular Neuroscience. 15: 602888
Benetó N, Vilageliu L, Grinberg D, et al. (2020) Sanfilippo Syndrome: Molecular Basis, Disease Models and Therapeutic Approaches. International Journal of Molecular Sciences. 21
Galera-Monge T, Zurita-Díaz F, Canals I, et al. (2020) Mitochondrial Dysfunction and Calcium Dysregulation in Leigh Syndrome Induced Pluripotent Stem Cell Derived Neurons. International Journal of Molecular Sciences. 21
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