Daniel N. Bolon, Ph.D.

Affiliations: 
Biochemistry and Molecular Pharmacology University of Massachusetts Medical School, Worcester, MA, United States 
Area:
molecular evolution
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"Daniel Bolon"
Cross-listing: Chemistry Tree

Parents

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Stephen L. Mayo grad student 1997-2002 Caltech (Chemistry Tree)
 (Computational enzyme design.)
Robert T. Sauer post-doc 2002-2005 MIT (Chemistry Tree)
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Publications

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Flynn JM, Rossouw A, Cote-Hammarlof P, et al. (2020) Comprehensive fitness maps of Hsp90 show widespread environmental dependence. Elife. 9
Bolon D. (2020) Lessons from Experimental Protein Fitness Landscapes Biophysical Journal. 118: 172a
Mavor D, Barlow KA, Asarnow D, et al. (2018) Extending chemical perturbations of the ubiquitin fitness landscape in a classroom setting reveals new constraints on sequence tolerance. Biology Open. 7
Canale AS, Cote-Hammarlof PA, Flynn JM, et al. (2018) Evolutionary mechanisms studied through protein fitness landscapes. Current Opinion in Structural Biology. 48: 141-148
Ma L, Boucher JI, Paulsen J, et al. (2017) CRISPR-Cas9-mediated saturated mutagenesis screen predicts clinical drug resistance with improved accuracy. Proceedings of the National Academy of Sciences of the United States of America
Ormond L, Liu P, Matuszewski S, et al. (2017) The Combined Effect of Oseltamivir and Favipiravir on Influenza A Virus Evolution. Genome Biology and Evolution. 9: 1913-1924
Prachanronarong KL, Özen A, Thayer KM, et al. (2016) Molecular Basis for Differential Patterns of Drug Resistance in Influenza N1 and N2 Neuraminidase. Journal of Chemical Theory and Computation. 12: 6098-6108
Duenas-Decamp M, Jiang L, Bolon D, et al. (2016) Saturation Mutagenesis of the HIV-1 Envelope CD4 Binding Loop Reveals Residues Controlling Distinct Trimer Conformations. Plos Pathogens. 12: e1005988
Mavor D, Barlow K, Thompson S, et al. (2016) Determination of ubiquitin fitness landscapes under different chemical stresses in a classroom setting. Elife. 5
Mishra P, Flynn JM, Starr TN, et al. (2016) Systematic Mutant Analyses Elucidate General and Client-Specific Aspects of Hsp90 Function. Cell Reports
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