Edel Hyland, PhD

Affiliations: 
2008 Johns Hopkins University School of Medicine, Baltimore, MD, United States 
 2009-2013 Harvard University, Cambridge, MA, United States 
 2013-2015 Biotechnology Dublin City University, Dublin, County Dublin, Ireland 
 2015- Biological Sciences Queen's University Belfast, Belfast, Northern Ireland, United Kingdom 
Area:
immunology, genetics, evolution
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"Edel Hyland"

Parents

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Jef D. Boeke grad student 2003-2008 NYU School of Medicine (Microtree)
Andrew W. Murray post-doc 2009-2013 Harvard (Cell Biology Tree)
Mary J. O'Connell post-doc 2013-2015 Dublin City University
 (Postdoc)
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Publications

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Hyland EM, Webb AE, Kennedy KF, et al. (2021) Adaptive Evolution in TRIF Leads to Discordance between Human and Mouse Innate Immune Signaling. Genome Biology and Evolution. 13
Am M, Hyland EM, Cormican P, et al. (2019) Gene Fusions derived by transcriptional readthrough are Driven by Segmental Duplication in Human. Genome Biology and Evolution
O'Kane CJ, Hyland EM. (2019) Yeast Epigenetics: The Inheritance of Histone Modification States. Bioscience Reports
O’Kane C, O’Connell M, Hyland E. (2019) Probing the role of histone modifications in the evolution of pathogenicity in Candida glabrata Access Microbiology. 1
Hoggard TA, Chang F, Perry KR, et al. (2018) Yeast heterochromatin regulators Sir2 and Sir3 act directly at euchromatic DNA replication origins. Plos Genetics. 14: e1007418
Hyland EM, Wallace EW, Murray AW. (2014) A model for the evolution of biological specificity: a cross-reacting DNA-binding protein causes plasmid incompatibility. Journal of Bacteriology. 196: 3002-11
Hyland EM, Molina H, Poorey K, et al. (2011) An evolutionarily 'young' lysine residue in histone H3 attenuates transcriptional output in Saccharomyces cerevisiae. Genes & Development. 25: 1306-19
Dai J, Hyland EM, Norris A, et al. (2010) Yin and Yang of histone H2B roles in silencing and longevity: a tale of two arginines. Genetics. 186: 813-28
Luo J, Xu X, Hall H, et al. (2010) Histone h3 exerts a key function in mitotic checkpoint control. Molecular and Cellular Biology. 30: 537-49
Huang H, Maertens AM, Hyland EM, et al. (2009) HistoneHits: a database for histone mutations and their phenotypes. Genome Research. 19: 674-81
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