Year |
Citation |
Score |
2023 |
Bae SW, Wang J, Georgiou DK, Wen X, Cohen AS, Geng L, Tantawy MN, Manning HC. Feasibility of [F]FSPG PET for Early Response Assessment to Combined Blockade of EGFR and Glutamine Metabolism in Wild-Type Colorectal Cancer. Tomography (Ann Arbor, Mich.). 9: 497-508. PMID 36961000 DOI: 10.3390/tomography9020041 |
0.312 |
|
2022 |
Lin M, Coll RP, Cohen AS, Georgiou DK, Manning HC. PET Oncological Radiopharmaceuticals: Current Status and Perspectives. Molecules (Basel, Switzerland). 27. PMID 36296381 DOI: 10.3390/molecules27206790 |
0.303 |
|
2020 |
Cohen AS, Li J, Hight MR, McKinley ET, Fu A, Payne AC, Liu Y, Zhang D, Xie Q, Bai M, Ayers GD, Tantawy MN, Smith JA, Revetta F, Washington MK, ... ... Manning HC, et al. TSPO-targeted PET and Optical Probes for the Detection and Localization of Pre-Malignant and Malignant Pancreatic Lesions. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32933996 DOI: 10.1158/1078-0432.Ccr-20-1214 |
0.509 |
|
2020 |
Cohen AS, Geng L, Zhao P, Fu A, Schulte ML, Graves-Deal R, Washington MK, Berlin J, Coffey RJ, Manning HC. Combined blockade of EGFR and glutamine metabolism in preclinical models of colorectal cancer. Translational Oncology. 13: 100828. PMID 32652471 DOI: 10.1016/J.Tranon.2020.100828 |
0.671 |
|
2020 |
Whisenant JG, Smith G, Cohen A, Ciombor KK, Cardin D, Eng C, Goff L, Das S, Hickman T, Fisher A, Payne A, Coffey R, Ayers GD, Berlin JD, Manning HC. Abstract 4260: Molecular imaging of glutamine (Gln) metabolism in RAS wildtype (WT) metastatic colorectal cancer (mCRC) Cancer Research. 80: 4260-4260. DOI: 10.1158/1538-7445.Am2020-4260 |
0.417 |
|
2019 |
Knapp KA, Nickels ML, Manning HC. The Current Role of Microfluidics in Radiofluorination Chemistry. Molecular Imaging and Biology. PMID 31485889 DOI: 10.1007/S11307-019-01414-6 |
0.345 |
|
2019 |
Uddin MJ, Wilson AJ, Crews BC, Malerba P, Uddin MI, Kingsley PJ, Ghebreselasie K, Daniel CK, Nickels ML, Tantawy MN, Jashim E, Manning HC, Khabele D, Marnett LJ. Discovery of Furanone-Based Radiopharmaceuticals for Diagnostic Targeting of COX-1 in Ovarian Cancer. Acs Omega. 4: 9251-9261. PMID 31172046 DOI: 10.1021/acsomega.9b01093 |
0.393 |
|
2019 |
Ciombor KK, Whisenant J, Cardin DB, Goff LW, Das S, Schulte M, Cohen A, Coffey RJ, Ayers GD, Krumsick R, Demo S, Whiting SH, Manning HC, Berlin J. CB-839, panitumumab, and irinotecan in RAS wildtype (WT) metastatic colorectal cancer (mCRC): Phase I results. Journal of Clinical Oncology. 37: 574-574. DOI: 10.1200/Jco.2019.37.4_Suppl.574 |
0.313 |
|
2018 |
Rosenberg AJ, Nickels ML, Schulte ML, Manning HC. Automated radiosynthesis of 5-[C]l-glutamine, an important tracer for glutamine utilization. Nuclear Medicine and Biology. 67: 10-14. PMID 30359787 DOI: 10.1016/J.Nucmedbio.2018.09.002 |
0.611 |
|
2018 |
Zhang Q, Jeppesen DK, Higginbotham JN, Demory Beckler M, Poulin EJ, Walsh AJ, Skala MC, McKinley ET, Manning HC, Hight MR, Schulte ML, Watt KR, Ayers GD, Wolf MM, Andrejeva G, et al. Mutant KRAS Exosomes Alter the Metabolic State of Recipient Colonic Epithelial Cells. Cellular and Molecular Gastroenterology and Hepatology. 5: 627-629.e6. PMID 29930982 DOI: 10.1016/J.Jcmgh.2018.01.013 |
0.589 |
|
2018 |
Tang D, Li J, Nickels ML, Huang G, Cohen AS, Manning HC. Preclinical Evaluation of a Novel TSPO PET Ligand 2-(7-Butyl-2-(4-(2-[F]Fluoroethoxy)phenyl)-5-Methylpyrazolo[1,5-a]Pyrimidin-3-yl)-N,N-Diethylacetamide (F-VUIIS1018A) to Image Glioma. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. PMID 29869061 DOI: 10.1007/S11307-018-1198-7 |
0.444 |
|
2018 |
Zhang X, Liu F, Knapp KA, Nickels ML, Manning HC, Bellan LM. A simple microfluidic platform for rapid and efficient production of the radiotracer [F]fallypride. Lab On a Chip. PMID 29658049 DOI: 10.1039/C8Lc00167G |
0.355 |
|
2018 |
Tang D, Fujinaga M, Hatori A, Zhang Y, Yamasaki T, Xie L, Mori W, Kumata K, Liu J, Manning HC, Huang G, Zhang MR. Evaluation of the novel TSPO radiotracer 2-(7-butyl-2-(4-(2-([F]fluoroethoxy)phenyl)-5-methylpyrazolo[1,5-a]pyrimidin-3-yl)-N,N-diethylacetamide in a preclinical model of neuroinflammation. European Journal of Medicinal Chemistry. 150: 1-8. PMID 29505933 DOI: 10.1016/J.Ejmech.2018.02.076 |
0.42 |
|
2018 |
Luo N, Nixon MJ, Gonzalez-Ericsson PI, Sanchez V, Opalenik SR, Li H, Zahnow CA, Nickels ML, Liu F, Tantawy MN, Sanders ME, Manning HC, Balko JM. DNA methyltransferase inhibition upregulates MHC-I to potentiate cytotoxic T lymphocyte responses in breast cancer. Nature Communications. 9: 248. PMID 29339738 DOI: 10.1038/S41467-017-02630-W |
0.372 |
|
2018 |
Schulte ML, Fu A, Zhao P, Li J, Geng L, Smith ST, Kondo J, Coffey RJ, Johnson MO, Rathmell JC, Sharick JT, Skala MC, Smith JA, Berlin J, Washington MK, ... ... Manning HC, et al. Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models. Nature Medicine. PMID 29334372 DOI: 10.1038/Nm.4464 |
0.66 |
|
2018 |
Das S, Cardin DB, Goff LW, Berlin J, Schulte M, Manning HC, Coffey RJ, Whisenant J, Krumsick R, Ciombor KK. Novel PET/CT imaging biomarkers of CB-839 in combination with panitumumab and irinotecan in patients with metastatic and refractory RAS wildtype (WT) colorectal cancer: A phase I/II study. Journal of Clinical Oncology. 36: TPS3616-TPS3616. DOI: 10.1200/Jco.2018.36.15_Suppl.Tps3616 |
0.354 |
|
2017 |
Magarik MA, Walker RC, Gilbert J, Manning HC, Massion PP. Intracardiac Metastases Detected by 18F-FSPG PET/CT. Clinical Nuclear Medicine. PMID 29076915 DOI: 10.1097/Rlu.0000000000001883 |
0.394 |
|
2017 |
Li J, Smith JA, Dawson ES, Fu A, Nickels M, Schulte ML, Manning HC. An Optimized Translocator Protein Ligand for Optical Molecular Imaging and Screening. Bioconjugate Chemistry. PMID 28156095 DOI: 10.1021/Acs.Bioconjchem.6B00711 |
0.69 |
|
2016 |
Xu J, Li K, Smith RA, Waterton JC, Zhao P, Ding Z, Does MD, Manning HC, Gore JC. A comparative assessment of preclinical chemotherapeutic response of tumors using quantitative non-Gaussian diffusion MRI. Magnetic Resonance Imaging. PMID 27919785 DOI: 10.1016/J.Mri.2016.12.002 |
0.544 |
|
2016 |
Tang D, Li J, Buck JR, Tantawy MN, Xia Y, Harp JM, Nickels ML, Meiler J, Manning HC. Evaluation of TSPO PET Ligands [(18)F]VUIIS1009A and [(18)F]VUIIS1009B: Tracers for Cancer Imaging. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. PMID 27853987 DOI: 10.1007/S11307-016-1027-9 |
0.405 |
|
2016 |
Schulte ML, Hight MR, Ayers GD, Liu Q, Shyr Y, Washington MK, Manning HC. Non-Invasive Glutamine PET Reflects Pharmacological Inhibition of BRAF(V600E) In Vivo. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. PMID 27770401 DOI: 10.1007/S11307-016-1008-Z |
0.68 |
|
2016 |
Kavanaugh G, Williams J, Morris AS, Nickels ML, Walker R, Koglin N, Stephens AW, Washington MK, Geevarghese SK, Liu Q, Ayers D, Shyr Y, Manning HC. Utility of [(18)F]FSPG PET to Image Hepatocellular Carcinoma: First Clinical Evaluation in a US Population. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. PMID 27677886 DOI: 10.1007/S11307-016-1007-0 |
0.342 |
|
2016 |
Osgood CL, Tantawy MN, Maloney N, Madaj ZB, Peck A, Boguslawski E, Jess J, Buck J, Winn ME, Manning HC, Grohar PJ. (18)F-FLT Positron Emission Tomography (PET) is a Pharmacodynamic Marker for EWS-FLI1 Activity and Ewing Sarcoma. Scientific Reports. 6: 33926. PMID 27671553 DOI: 10.1038/Srep33926 |
0.384 |
|
2016 |
Li J, Schulte ML, Nickels ML, Manning HC. New structure-activity relationships of N-acetamide substituted pyrazolopyrimidines as pharmacological ligands of TSPO. Bioorganic & Medicinal Chemistry Letters. PMID 27353534 DOI: 10.1016/J.Bmcl.2016.06.041 |
0.625 |
|
2016 |
Higginbotham JN, Zhang Q, Jeppesen DK, Scott AM, Manning HC, Ochieng J, Franklin JL, Coffey RJ. Identification and characterization of EGF receptor in individual exosomes by fluorescence-activated vesicle sorting. Journal of Extracellular Vesicles. 5: 29254. PMID 27345057 DOI: 10.3402/Jev.V5.29254 |
0.323 |
|
2016 |
Manning HC, Buck JR, Cook RS. Mouse Models of Breast Cancer: Platforms for Discovering Precision Imaging Diagnostics and Future Cancer Medicine. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 57: 60S-8S. PMID 26834104 DOI: 10.2967/Jnumed.115.157917 |
0.37 |
|
2015 |
Schulte ML, Khodadadi AB, Cuthbertson ML, Smith JA, Manning HC. 2-Amino-4-bis(aryloxybenzyl)aminobutanoic acids: A novel scaffold for inhibition of ASCT2-mediated glutamine transport. Bioorganic & Medicinal Chemistry Letters. PMID 26750251 DOI: 10.1016/J.Bmcl.2015.12.031 |
0.626 |
|
2015 |
Buck JR, McKinley ET, Fu A, Abel TW, Thompson RC, Chambless L, Watchmaker JM, Harty JP, Cooper MK, Manning HC. Preclinical TSPO Ligand PET to Visualize Human Glioma Xenotransplants: A Preliminary Study. Plos One. 10: e0141659. PMID 26517124 DOI: 10.1371/Journal.Pone.0141659 |
0.458 |
|
2015 |
Hassanein M, Hight MR, Buck JR, Tantawy MN, Nickels ML, Hoeksema MD, Harris BK, Boyd K, Massion PP, Manning HC. Preclinical Evaluation of 4-[(18)F]Fluoroglutamine PET to Assess ASCT2 Expression in Lung Cancer. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. PMID 25971659 DOI: 10.1007/S11307-015-0862-4 |
0.361 |
|
2015 |
Manning HC. World Molecular Imaging Congress 2015: precision medicine visualized. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 17: 295-6. PMID 25862478 DOI: 10.1007/S11307-015-0855-3 |
0.334 |
|
2015 |
Cheung YY, Nickels ML, McKinley ET, Buck JR, Manning HC. High-yielding, automated production of 3'-deoxy-3'-[(18)F]fluorothymidine using a modified Bioscan Coincidence FDG reaction module. Applied Radiation and Isotopes : Including Data, Instrumentation and Methods For Use in Agriculture, Industry and Medicine. 97: 47-51. PMID 25531913 DOI: 10.1016/J.Apradiso.2014.11.011 |
0.304 |
|
2015 |
Schulte ML, Dawson ES, Saleh SA, Cuthbertson ML, Manning HC. 2-Substituted Nγ-glutamylanilides as novel probes of ASCT2 with improved potency. Bioorganic & Medicinal Chemistry Letters. 25: 113-6. PMID 25435145 DOI: 10.1016/J.Bmcl.2014.10.098 |
0.631 |
|
2015 |
Whisenant JG, McIntyre JO, Peterson TE, Kang H, Sánchez V, Manning HC, Arteaga CL, Yankeelov TE. Utility of [18 F]FLT-PET to assess treatment response in trastuzumab-resistant and trastuzumab-sensitive HER2-overexpressing human breast cancer xenografts. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 17: 119-28. PMID 25034624 DOI: 10.1007/S11307-014-0770-Z |
0.368 |
|
2015 |
Bardia A, Dickler MN, Mayer IA, Winer EP, Mahmood U, Ulaner G, Manning HC, Rix P, Hager JH, Roychowdhury D, Maneval EC, Arteaga CL, Baselga J. Abstract P1-13-01: Phase I study of ARN-810, a novel and potent oral selective estrogen receptor degrader, in postmenopausal women with metastatic estrogen receptor positive (ER+), HER2- breast cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P1-13-01 |
0.371 |
|
2014 |
Comerford SA, Huang Z, Du X, Wang Y, Cai L, Witkiewicz AK, Walters H, Tantawy MN, Fu A, Manning HC, Horton JD, Hammer RE, McKnight SL, Tu BP. Acetate dependence of tumors. Cell. 159: 1591-602. PMID 25525877 DOI: 10.1016/J.Cell.2014.11.020 |
0.331 |
|
2014 |
McKinley ET, Zhao P, Coffey RJ, Washington MK, Manning HC. 3'-Deoxy-3'-[18F]-Fluorothymidine PET imaging reflects PI3K-mTOR-mediated pro-survival response to targeted therapy in colorectal cancer. Plos One. 9: e108193. PMID 25247710 DOI: 10.1371/Journal.Pone.0108193 |
0.446 |
|
2014 |
Cheung YY, Nickels ML, Tang D, Buck JR, Manning HC. Facile synthesis of SSR180575 and discovery of 7-chloro-N,N,5-trimethyl-4-oxo-3(6-[(18)F]fluoropyridin-2-yl)-3,5-dihydro-4H-pyridazino[4,5-b]indole-1-acetamide, a potent pyridazinoindole ligand for PET imaging of TSPO in cancer. Bioorganic & Medicinal Chemistry Letters. 24: 4466-71. PMID 25172419 DOI: 10.1016/J.Bmcl.2014.07.091 |
0.349 |
|
2014 |
Tang D, Nickels ML, Tantawy MN, Buck JR, Manning HC. Preclinical imaging evaluation of novel TSPO-PET ligand 2-(5,7-Diethyl-2-(4-(2-[(18)F]fluoroethoxy)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)-N,N-diethylacetamide ([ (18)F]VUIIS1008) in glioma. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 16: 813-20. PMID 24845529 DOI: 10.1007/S11307-014-0743-2 |
0.392 |
|
2014 |
Powell AE, Vlacich G, Zhao ZY, McKinley ET, Washington MK, Manning HC, Coffey RJ. Inducible loss of one Apc allele in Lrig1-expressing progenitor cells results in multiple distal colonic tumors with features of familial adenomatous polyposis. American Journal of Physiology. Gastrointestinal and Liver Physiology. 307: G16-23. PMID 24833705 DOI: 10.1152/Ajpgi.00358.2013 |
0.371 |
|
2014 |
Perrone MG, Malerba P, Uddin MJ, Vitale P, Panella A, Crews BC, Daniel CK, Ghebreselasie K, Nickels M, Tantawy MN, Manning HC, Marnett LJ, Scilimati A. PET radiotracer [¹⁸F]-P6 selectively targeting COX-1 as a novel biomarker in ovarian cancer: preliminary investigation. European Journal of Medicinal Chemistry. 80: 562-8. PMID 24832612 DOI: 10.1016/J.Ejmech.2014.04.074 |
0.43 |
|
2014 |
Hight MR, Cheung YY, Nickels ML, Dawson ES, Zhao P, Saleh S, Buck JR, Tang D, Washington MK, Coffey RJ, Manning HC. A peptide-based positron emission tomography probe for in vivo detection of caspase activity in apoptotic cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 2126-35. PMID 24573549 DOI: 10.1158/1078-0432.Ccr-13-2444 |
0.386 |
|
2014 |
Uddin MI, Buck JR, Schulte ML, Tang D, Saleh SA, Cheung YY, Harp J, Manning HC. Microwave-assisted, one-pot reaction of 7-azaindoles and aldehydes: a facile route to novel di-7-azaindolylmethanes. Tetrahedron Letters. 55. PMID 24396154 DOI: 10.1016/J.Tetlet.2013.10.143 |
0.587 |
|
2014 |
Hebron KE, Ketova T, Arnold S, Manning HC, Sterling J, Elefteriou F, Zijsltra A. Abstract 4958: Fluorescent barcoding offers increased dimensionality in tracking tumor cells in vitro and in vivo Cancer Research. 74: 4958-4958. DOI: 10.1158/1538-7445.Am2014-4958 |
0.402 |
|
2014 |
Hight MR, Schulte ML, Saleh S, Ayers GD, Revetta FL, Washington MK, Coffey RJ, Manning HC. Abstract 2058: Molecular imaging of glutaminolysis as a tool for evaluating therapeutic response in preclinical models of colorectal cancer Cancer Research. 74: 2058-2058. DOI: 10.1158/1538-7445.Am2014-2058 |
0.459 |
|
2014 |
Cheung Y, Buck JR, Nickels ML, Tang D, Manning HC. Abstract 110: Preclinical evaluation of 7-chloro-N,N,5-trimethyl-4-oxo-3(6-[18F]fluoropyridin-2-yl)-3,5-dihydro-4H-pyridazino[4,5-b]indole-1-acetamide: A novel pyridazinoindole ligand for PET imaging of TSPO in cancer Cancer Research. 74: 110-110. DOI: 10.1158/1538-7445.Am2014-110 |
0.468 |
|
2013 |
McKinley ET, Liu H, McDonald WH, Luo W, Zhao P, Coffey RJ, Hanks SK, Manning HC. Global phosphotyrosine proteomics identifies PKCδ as a marker of responsiveness to Src inhibition in colorectal cancer. Plos One. 8: e80207. PMID 24260357 DOI: 10.1371/Journal.Pone.0080207 |
0.379 |
|
2013 |
Walsh AJ, Cook RS, Manning HC, Hicks DJ, Lafontant A, Arteaga CL, Skala MC. Optical metabolic imaging identifies glycolytic levels, subtypes, and early-treatment response in breast cancer. Cancer Research. 73: 6164-74. PMID 24130112 DOI: 10.1158/0008-5472.Can-13-0527 |
0.39 |
|
2013 |
Xie J, Wang C, Virostko J, Manning HC, Pham W, Bauer J, Gore JC. A novel reporter system for molecular imaging and high-throughput screening of anticancer drugs. Chembiochem : a European Journal of Chemical Biology. 14: 1494-503. PMID 23881799 DOI: 10.1002/Cbic.201300142 |
0.48 |
|
2013 |
Goode GD, Ballard BR, Manning HC, Freeman ML, Kang Y, Eltom SE. Knockdown of aberrantly upregulated aryl hydrocarbon receptor reduces tumor growth and metastasis of MDA-MB-231 human breast cancer cell line. International Journal of Cancer. Journal International Du Cancer. 133: 2769-80. PMID 23733406 DOI: 10.1002/Ijc.28297 |
0.394 |
|
2013 |
McKinley ET, Ayers GD, Smith RA, Saleh SA, Zhao P, Washington MK, Coffey RJ, Manning HC. Limits of [18F]-FLT PET as a biomarker of proliferation in oncology. Plos One. 8: e58938. PMID 23554961 DOI: 10.1371/Journal.Pone.0058938 |
0.391 |
|
2013 |
Tang D, McKinley ET, Hight MR, Uddin MI, Harp JM, Fu A, Nickels ML, Buck JR, Manning HC. Synthesis and structure-activity relationships of 5,6,7-substituted pyrazolopyrimidines: discovery of a novel TSPO PET ligand for cancer imaging. Journal of Medicinal Chemistry. 56: 3429-33. PMID 23521048 DOI: 10.1021/Jm4001874 |
0.407 |
|
2013 |
McKinley ET, Smith RA, Zhao P, Fu A, Saleh SA, Uddin MI, Washington MK, Coffey RJ, Manning HC. 3'-Deoxy-3'-18F-fluorothymidine PET predicts response to (V600E)BRAF-targeted therapy in preclinical models of colorectal cancer. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 54: 424-30. PMID 23341544 DOI: 10.2967/jnumed.112.108456 |
0.3 |
|
2013 |
Powell A, Vlacich GR, Lee E, Manning HC, Coffey RJ. 310 Applying Novel Imaging and Therapy to a New Mouse Model of Colon Cancer Gastroenterology. 144: S-64-S-65. DOI: 10.1016/S0016-5085(13)60234-6 |
0.401 |
|
2013 |
Yankeelov TE, Peterson TE, Abramson RG, Izquierdo-Garcia D, Arlinghaus LR, Li X, Atuegwu NC, Catana C, Manning HC, Fayad ZA, Gore JC. Erratum to “Simultaneous PET–MRI in oncology: A solution looking for a problem?” [Magn Reson Imaging 30 (2012):1342–1356] Magnetic Resonance Imaging. 31: 796. DOI: 10.1016/J.Mri.2013.01.015 |
0.461 |
|
2012 |
Buck JR, Saleh S, Uddin MI, Manning HC. Rapid, Microwave-Assisted Organic Synthesis of Selective (V600E)BRAF Inhibitors for Preclinical Cancer Research. Tetrahedron Letters. 53: 4161-4165. PMID 23180892 DOI: 10.1016/J.Tetlet.2012.05.137 |
0.301 |
|
2012 |
Xu J, Li K, Smith RA, Waterton JC, Zhao P, Chen H, Does MD, Manning HC, Gore JC. Characterizing tumor response to chemotherapy at various length scales using temporal diffusion spectroscopy. Plos One. 7: e41714. PMID 22911846 DOI: 10.1371/Journal.Pone.0041714 |
0.583 |
|
2012 |
Wang C, Xie J, Guo J, Manning HC, Gore JC, Guo N. Evaluation of CD44 and CD133 as cancer stem cell markers for colorectal cancer. Oncology Reports. 28: 1301-8. PMID 22895640 DOI: 10.3892/Or.2012.1951 |
0.431 |
|
2012 |
McKinley ET, Smith RA, Tanksley JP, Washington MK, Walker R, Coffey RJ, Manning HC. [18F]FLT-PET to predict pharmacodynamic and clinical response to cetuximab therapy in Ménétrier's disease. Annals of Nuclear Medicine. 26: 757-63. PMID 22821337 DOI: 10.1007/S12149-012-0636-X |
0.351 |
|
2012 |
Yankeelov TE, Peterson TE, Abramson RG, Izquierdo-Garcia D, Garcia-Izquierdo D, Arlinghaus LR, Li X, Atuegwu NC, Catana C, Manning HC, Fayad ZA, Gore JC. Simultaneous PET-MRI in oncology: a solution looking for a problem? Magnetic Resonance Imaging. 30: 1342-56. PMID 22795930 DOI: 10.1016/J.Mri.2012.06.001 |
0.508 |
|
2012 |
Wyatt SK, Manning HC, Bai M, Ehtesham M, Mapara KY, Thompson RC, Bornhop DJ. Preclinical molecular imaging of the translocator protein (TSPO) in a metastases model based on breast cancer xenografts propagated in the murine brain. Current Molecular Medicine. 12: 458-66. PMID 22348613 DOI: 10.2174/156652412800163361 |
0.793 |
|
2012 |
Tang D, Hight MR, McKinley ET, Fu A, Buck JR, Smith RA, Tantawy MN, Peterson TE, Colvin DC, Ansari MS, Nickels M, Manning HC. Quantitative preclinical imaging of TSPO expression in glioma using N,N-diethyl-2-(2-(4-(2-18F-fluoroethoxy)phenyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl)acetamide. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 53: 287-94. PMID 22251555 DOI: 10.2967/Jnumed.111.095653 |
0.75 |
|
2012 |
Myers MV, Manning HC, Coffey RJ, Liebler DC. Protein expression signatures for inhibition of epidermal growth factor receptor-mediated signaling. Molecular & Cellular Proteomics : McP. 11: M111.015222. PMID 22147731 DOI: 10.1074/Mcp.M111.015222 |
0.313 |
|
2012 |
Buck JR, Saleh S, Hight MR, Nickels ML, Manning HC. Abstract 5743: Positron emission tomography (PET) imaging analogs of glutamine: Development and evaluation as probes for cancer imaging Cancer Research. 72: 5743-5743. DOI: 10.1158/1538-7445.Am2012-5743 |
0.452 |
|
2011 |
Fox EM, Miller TW, Balko JM, Kuba MG, Sánchez V, Smith RA, Liu S, González-Angulo AM, Mills GB, Ye F, Shyr Y, Manning HC, Buck E, Arteaga CL. A kinome-wide screen identifies the insulin/IGF-I receptor pathway as a mechanism of escape from hormone dependence in breast cancer. Cancer Research. 71: 6773-84. PMID 21908557 DOI: 10.1158/0008-5472.Can-11-1295 |
0.341 |
|
2011 |
Gore JC, Manning HC, Quarles CC, Waddell KW, Yankeelov TE. Magnetic resonance in the era of molecular imaging of cancer. Magnetic Resonance Imaging. 29: 587-600. PMID 21524870 DOI: 10.1016/J.Mri.2011.02.003 |
0.576 |
|
2011 |
Hight MR, Nolting DD, McKinley ET, Lander AD, Wyatt SK, Gonyea M, Zhao P, Manning HC. Multispectral fluorescence imaging to assess pH in biological specimens. Journal of Biomedical Optics. 16: 016007. PMID 21280913 DOI: 10.1117/1.3533264 |
0.729 |
|
2011 |
McKinley ET, Bugaj JE, Zhao P, Guleryuz S, Mantis C, Gokhale PC, Wild R, Manning HC. 18FDG-PET predicts pharmacodynamic response to OSI-906, a dual IGF-1R/IR inhibitor, in preclinical mouse models of lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 3332-40. PMID 21257723 DOI: 10.1158/1078-0432.Ccr-10-2274 |
0.347 |
|
2011 |
Smith RA, Guleryuz S, Manning HC. Molecular imaging metrics to evaluate response to preclinical therapeutic regimens. Frontiers in Bioscience (Landmark Edition). 16: 393-410. PMID 21196177 DOI: 10.2741/3694 |
0.309 |
|
2011 |
Buck JR, McKinley ET, Hight MR, Fu A, Tang D, Smith RA, Tantawy MN, Peterson TE, Colvin D, Ansari MS, Baldwin RM, Zhao P, Guleryuz S, Manning HC. Quantitative, preclinical PET of translocator protein expression in glioma using 18F-N-fluoroacetyl-N-(2,5-dimethoxybenzyl)-2-phenoxyaniline. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 52: 107-14. PMID 21149488 DOI: 10.2967/Jnumed.110.081703 |
0.749 |
|
2011 |
Guo N, Xie J, Manning HC, Deane NG, Ansari MS, Coffey RJ, Gore J, Price RR, Baldwin RM, McIntyre JO. A novel in vitro assay to assess phosphorylation of 3'-[(18)F]fluoro-3'-deoxythymidine. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 13: 257-64. PMID 20532643 DOI: 10.1007/S11307-010-0351-8 |
0.476 |
|
2010 |
Tang D, Buck JR, Hight MR, Manning HC. Microwave-assisted Organic Synthesis of a High-affinity Pyrazolo-pyrimidinyl TSPO Ligand. Tetrahedron Letters. 51: 4595-4598. PMID 20689673 DOI: 10.1016/J.Tetlet.2010.06.074 |
0.333 |
|
2010 |
Ayers GD, McKinley ET, Zhao P, Fritz JM, Metry RE, Deal BC, Adlerz KM, Coffey RJ, Manning HC. Volume of preclinical xenograft tumors is more accurately assessed by ultrasound imaging than manual caliper measurements. Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine. 29: 891-901. PMID 20498463 DOI: 10.7863/Jum.2010.29.6.891 |
0.39 |
|
2010 |
Wyatt SK, Manning HC, Bai M, Bailey SN, Gallant P, Ma G, McIntosh L, Bornhop DJ. Molecular imaging of the translocator protein (TSPO) in a pre-clinical model of breast cancer. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 12: 349-58. PMID 19949989 DOI: 10.1007/S11307-009-0270-8 |
0.794 |
|
2010 |
Bugaj JE, McKinley E, Manning HC, Zhao P, Mantis C, Gokhale PC, Wild R. Abstract 5244: Preclinical, real-time assessment of early pharmacodynamic effects for the IGF-1R/IR inhibitor OSI-906 by [18F]-FDG-PET Cancer Research. 70: 5244-5244. DOI: 10.1158/1538-7445.Am10-5244 |
0.363 |
|
2009 |
Sexton M, Woodruff G, Cudaback E, Kreitzer FR, Xu C, Lin YH, Möller T, Bai M, Manning HC, Bornhop D, Stella N. Binding of NIR-conPK and NIR-6T to astrocytomas and microglial cells: evidence for a protein related to TSPO. Plos One. 4: e8271. PMID 20020060 DOI: 10.1371/Journal.Pone.0008271 |
0.684 |
|
2009 |
Miller TW, Forbes JT, Shah C, Wyatt SK, Manning HC, Olivares MG, Sanchez V, Dugger TC, de Matos Granja N, Narasanna A, Cook RS, Kennedy JP, Lindsley CW, Arteaga CL. Inhibition of mammalian target of rapamycin is required for optimal antitumor effect of HER2 inhibitors against HER2-overexpressing cancer cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 7266-76. PMID 19934303 DOI: 10.1158/1078-0432.Ccr-09-1665 |
0.768 |
|
2009 |
Yankeelov TE, Avison MJ, Damon BM, Manning HC, Peterson TE, Gore JC. Frontiers of Biomedical Imaging Science 2009: workshop report and research opportunities. Cancer Research. 69: 7902-4. PMID 19808955 DOI: 10.1158/0008-5472.Can-09-2521 |
0.7 |
|
2009 |
Peterson TE, Manning HC. Molecular imaging: 18F-FDG PET and a whole lot more. Journal of Nuclear Medicine Technology. 37: 151-61. PMID 19692452 DOI: 10.2967/Jnmt.109.062729 |
0.428 |
|
2009 |
Shah C, Miller TW, Wyatt SK, McKinley ET, Olivares MG, Sanchez V, Nolting DD, Buck JR, Zhao P, Ansari MS, Baldwin RM, Gore JC, Schiff R, Arteaga CL, Manning HC. Imaging biomarkers predict response to anti-HER2 (ErbB2) therapy in preclinical models of breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 4712-21. PMID 19584166 DOI: 10.1158/1078-0432.Ccr-08-2635 |
0.781 |
|
2009 |
Virostko J, Xie J, Hallahan DE, Arteaga CL, Gore JC, Manning HC. A molecular imaging paradigm to rapidly profile response to angiogenesis-directed therapy in small animals. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 11: 204-12. PMID 19130143 DOI: 10.1007/S11307-008-0193-9 |
0.571 |
|
2008 |
Manning HC, Merchant NB, Foutch AC, Virostko JM, Wyatt SK, Shah C, McKinley ET, Xie J, Mutic NJ, Washington MK, LaFleur B, Tantawy MN, Peterson TE, Ansari MS, Baldwin RM, et al. Molecular imaging of therapeutic response to epidermal growth factor receptor blockade in colorectal cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 7413-22. PMID 19010858 DOI: 10.1158/1078-0432.Ccr-08-0239 |
0.806 |
|
2008 |
Manning HC, Lander A, McKinley E, Mutic NJ. Accelerating the development of novel molecular imaging probes: a role for high-throughput screening. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 49: 1401-4. PMID 18703594 DOI: 10.2967/jnumed.108.053009 |
0.326 |
|
2008 |
Manning HC, Merchant NB, Foutch AC, Viostko J, Wyatt SK, Washington MK, Lafleur B, Baldwin R, Bornhop DJ, Gore JC, Coffey RJ. QS107. Non-Invasive Molecular Imaging Biomarkers of Therapeutic Response in Colorectal Cancer Journal of Surgical Research. 144: 310. DOI: 10.1016/J.Jss.2007.12.347 |
0.762 |
|
2007 |
Deane NG, Manning HC, Foutch AC, Washington MK, Aronow BJ, Aronow BA, Bornhop DJ, Coffey RJ. Targeted imaging of colonic tumors in smad3-/- mice discriminates cancer and inflammation. Molecular Cancer Research : McR. 5: 341-9. PMID 17426249 DOI: 10.1158/1541-7786.Mcr-06-0225 |
0.669 |
|
2006 |
Manning HC, Smith SM, Sexton M, Haviland S, Bai M, Cederquist K, Stella N, Bornhop DJ. A peripheral benzodiazepine receptor targeted agent for in vitro imaging and screening. Bioconjugate Chemistry. 17: 735-40. PMID 16704212 DOI: 10.1021/Bc060020B |
0.739 |
|
2005 |
Manning HC, Bai M, Anderson BM, Lisiak R, Samuelson LE, Bornhop DJ. Expeditious synthesis of 'P'-protected macrocycles en route to lanthanide chelate metal complexes Tetrahedron Letters. 46: 4707-4710. DOI: 10.1016/J.Tetlet.2005.05.049 |
0.677 |
|
2004 |
Manning HC, Goebel T, Thompson RC, Price RR, Lee H, Bornhop DJ. Targeted molecular imaging agents for cellular-scale bimodal imaging. Bioconjugate Chemistry. 15: 1488-95. PMID 15546219 DOI: 10.1021/Bc049904Q |
0.679 |
|
2004 |
Bornhop DJ, Manning HC, Smith S, Wyatt S, Sexton M, Thompson R, Ehtesham M. Bimodal molecular imaging with lanthanide chelates Frontiers in Optics. DOI: 10.1364/Fio.2004.Fthr1 |
0.784 |
|
2003 |
Marcu L, Vernier PT, Manning HC, Salemi S, Li A, Craft CM, Gundersen MA, Bornhop DJ. Fluorescence microscopy studies of a peripheral benzodiazepine receptor targeted molecular probe for brain tumor imaging Proceedings of Spie - the International Society For Optical Engineering. 5141: 64-69. |
0.608 |
|
2002 |
Manning HC, Goebel T, Marx JN, Bornhop DJ. Facile, efficient conjugation of a trifunctional lanthanide chelate to a peripheral benzodiazepine receptor ligand. Organic Letters. 4: 1075-8. PMID 11922786 DOI: 10.1021/Ol017155B |
0.623 |
|
2001 |
Griffin JMM, Skwierawska AM, Manning HC, Marx JN, Bornhop DJ. Simple, high yielding synthesis of trifunctional fluorescent lanthanide chelates Tetrahedron Letters. 42: 3823-3825. DOI: 10.1016/S0040-4039(01)00620-7 |
0.568 |
|
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