| Year |
Citation |
Score |
| 2022 |
Chang S, Fulmer D, Hur SK, Thorvaldsen JL, Li L, Lan Y, Rhon-Calderon EA, Leu NA, Chen X, Epstein JA, Bartolomei MS. Dysregulated expression disrupts cardiac-placental axis during development of Silver-Russell syndrome-like mouse models. Elife. 11. PMID 36441651 DOI: 10.7554/eLife.78754 |
0.352 |
|
| 2020 |
Jang J, Engleka KA, Liu F, Li L, Song G, Epstein JA, Li D. An Engineered Mouse to Identify Proliferating Cells and Their Derivatives. Frontiers in Cell and Developmental Biology. 8: 388. PMID 32523954 DOI: 10.3389/Fcell.2020.00388 |
0.333 |
|
| 2019 |
Poleshko A, Smith CL, Nguyen SC, Sivaramakrishnan P, Wong KG, Murray JI, Lakadamyali M, Joyce EF, Jain R, Epstein JA. H3K9me2 orchestrates inheritance of spatial positioning of peripheral heterochromatin through mitosis. Elife. 8. PMID 31573510 DOI: 10.7554/Elife.49278 |
0.301 |
|
| 2019 |
Aghajanian H, Kimura T, Rurik JG, Hancock AS, Leibowitz MS, Li L, Scholler J, Monslow J, Lo A, Han W, Wang T, Bedi K, Morley MP, Linares Saldana RA, Bolar NA, ... ... Epstein JA, et al. Targeting cardiac fibrosis with engineered T cells. Nature. PMID 31511695 DOI: 10.1038/S41586-019-1546-Z |
0.399 |
|
| 2019 |
Sandireddy R, Cibi DM, Gupta P, Singh A, Tee N, Uemura A, Epstein JA, Singh MK. Semaphorin 3E/PlexinD1 signaling is required for cardiac ventricular compaction. Jci Insight. 4. PMID 31434798 DOI: 10.1172/Jci.Insight.125908 |
0.443 |
|
| 2019 |
Berg DA, Su Y, Jimenez-Cyrus D, Patel A, Huang N, Morizet D, Lee S, Shah R, Ringeling FR, Jain R, Epstein JA, Wu QF, Canzar S, Ming GL, Song H, et al. A Common Embryonic Origin of Stem Cells Drives Developmental and Adult Neurogenesis. Cell. PMID 30929900 DOI: 10.1016/J.Cell.2019.02.010 |
0.338 |
|
| 2019 |
See K, Lan Y, Rhoades J, Jain R, Smith CL, Epstein JA. Lineage-specific reorganization of nuclear peripheral heterochromatin and H3K9me2 domains. Development (Cambridge, England). 146. PMID 30723106 DOI: 10.1242/Dev.174078 |
0.404 |
|
| 2019 |
Sandireddy R, Cibi DM, Singh A, Tee N, Uemura A, Epstein JA, Singh MK. Abstract 633: Semaphorin3e-Plexind1 Signaling is Required for Cardiac Ventricular Compaction Circulation Research. 125. DOI: 10.1161/Res.125.Suppl_1.633 |
0.344 |
|
| 2018 |
Jain R, Poleshko A, Epstein JA. Beating the odds: programming proliferation in the mammalian heart. Genome Medicine. 10: 36. PMID 29776422 DOI: 10.1186/S13073-018-0550-5 |
0.374 |
|
| 2018 |
Artap S, Manderfield LJ, Smith CL, Poleshko A, Aghajanian H, See K, Li L, Jain R, Epstein JA. Endocardial Hippo signaling regulates myocardial growth and cardiogenesis. Developmental Biology. PMID 29727635 DOI: 10.1016/J.Ydbio.2018.04.026 |
0.4 |
|
| 2018 |
Jain R, Epstein JA. Competent for commitment: you've got to have heart! Genes & Development. 32: 4-13. PMID 29440224 DOI: 10.1101/Gad.308353.117 |
0.446 |
|
| 2018 |
Lin W, Li D, Cheng L, Li L, Liu F, Hand NJ, Epstein JA, Rader DJ. Zinc transporter Slc39a8 is essential for cardiac ventricular compaction. The Journal of Clinical Investigation. PMID 29337306 DOI: 10.1172/Jci96993 |
0.428 |
|
| 2017 |
Poleshko A, Shah PP, Gupta M, Babu A, Morley MP, Manderfield LJ, Ifkovits JL, Calderon D, Aghajanian H, Sierra-Pagán JE, Sun Z, Wang Q, Li L, Dubois NC, Morrisey EE, ... ... Epstein JA, et al. Genome-Nuclear Lamina Interactions Regulate Cardiac Stem Cell Lineage Restriction. Cell. PMID 29033129 DOI: 10.1016/J.Cell.2017.09.018 |
0.427 |
|
| 2017 |
Pauerstein PT, Tellez K, Willmarth KB, Park KM, Hsueh B, Arda HE, Gu X, Aghajanian H, Deisseroth K, Epstein JA, Kim SK. A radial axis defined by Semaphorin to Neuropilin signaling controls pancreatic islet morphogenesis. Development (Cambridge, England). PMID 28893946 DOI: 10.1242/Dev.148684 |
0.348 |
|
| 2017 |
Bardot E, Calderon D, Santoriello F, Han S, Cheung K, Jadhav B, Burtscher I, Artap S, Jain R, Epstein J, Lickert H, Gouon-Evans V, Sharp AJ, Dubois NC. Foxa2 identifies a cardiac progenitor population with ventricular differentiation potential. Nature Communications. 8: 14428. PMID 28195173 DOI: 10.1038/ncomms14428 |
0.302 |
|
| 2017 |
Ramjee V, Li D, Manderfield LJ, Liu F, Engleka KA, Aghajanian H, Rodell CB, Lu W, Ho V, Wang T, Li L, Singh A, Cibi DM, Burdick JA, Singh MK, ... ... Epstein JA, et al. Epicardial YAP/TAZ orchestrate an immunosuppressive response following myocardial infarction. The Journal of Clinical Investigation. PMID 28165342 DOI: 10.1172/Jci88759 |
0.353 |
|
| 2016 |
Loh KM, Chen A, Koh PW, Deng TZ, Sinha R, Tsai JM, Barkal AA, Shen KY, Jain R, Morganti RM, Shyh-Chang N, Fernhoff NB, George BM, Wernig G, Salomon RE, ... ... Epstein JA, et al. Mapping the Pairwise Choices Leading from Pluripotency to Human Bone, Heart, and Other Mesoderm Cell Types. Cell. 166: 451-467. PMID 27419872 DOI: 10.1016/J.Cell.2016.06.011 |
0.39 |
|
| 2016 |
Aghajanian H, Cho YK, Manderfield LJ, Herling MR, Gupta M, Ho VC, Li L, Degenhardt K, Aharonov A, Tzahor E, Epstein JA. Coronary vasculature patterning requires a novel endothelial ErbB2 holoreceptor. Nature Communications. 7: 12038. PMID 27356767 DOI: 10.1038/Ncomms12038 |
0.314 |
|
| 2016 |
Singh A, Ramesh S, Cibi DM, Yun LS, Li J, Li L, Manderfield LJ, Olson EN, Epstein JA, Singh MK. Hippo Signaling Mediators Yap and Taz Are Required in the Epicardium for Coronary Vasculature Development. Cell Reports. PMID 27160901 DOI: 10.1016/J.Celrep.2016.04.027 |
0.399 |
|
| 2016 |
He S, Mansour MR, Zimmerman MW, Ki DH, Layden HM, Akahane K, Gjini E, de Groh ED, Perez-Atayde AR, Zhu S, Epstein JA, Look AT. Synergy between loss of NF1 and overexpression of MYCN in neuroblastoma is mediated by the GAP-related domain. Elife. 5. PMID 27130733 DOI: 10.7554/Elife.14713 |
0.353 |
|
| 2016 |
He S, Mansour MR, Zimmerman MW, Ki DH, Layden HM, Akahane K, Groh EDd, Perez-Atayde AR, Zhu S, Epstein JA, Look AT. Abstract 2456: Synergy between loss of NF1 and overexpression of MYCN in neuroblastoma is mediated by the GAP-related domain Cancer Research. 76: 2456-2456. DOI: 10.1158/1538-7445.Am2016-2456 |
0.346 |
|
| 2015 |
Manderfield LJ, Engleka KA, Aghajanian H, Gupta M, Yang S, Li L, Baggs JE, Hogenesch JB, Olson EN, Epstein JA. Pax3 and Hippo Signaling Coordinate Melanocyte Gene Expression in Neural Crest. Cell Reports. 10: 841. PMID 30849859 DOI: 10.1016/J.Celrep.2015.01.041 |
0.379 |
|
| 2015 |
Yzaguirre AD, Padmanabhan A, de Groh ED, Engleka KA, Li J, Speck NA, Epstein JA. Loss of neurofibromin Ras-GAP activity enhances the formation of cardiac blood islands in murine embryos. Elife. 4. PMID 26460546 DOI: 10.7554/Elife.07780 |
0.631 |
|
| 2015 |
Li D, Takeda N, Jain R, Manderfield LJ, Liu F, Li L, Anderson SA, Epstein JA. Hopx distinguishes hippocampal from lateral ventricle neural stem cells. Stem Cell Research. 15: 522-529. PMID 26451648 DOI: 10.1016/J.Scr.2015.09.015 |
0.393 |
|
| 2015 |
Manderfield LJ, Aghajanian H, Engleka KA, Lim LY, Lui F, Jain R, Li L, Olson EN, Epstein JA. Hippo signaling is required for Notch-dependent smooth muscle differentiation of neural crest. Development (Cambridge, England). PMID 26253400 DOI: 10.1242/Dev.125807 |
0.393 |
|
| 2015 |
Jain R, Li D, Gupta M, Manderfield LJ, Ifkovits JL, Wang Q, Liu F, Liu Y, Poleshko A, Padmanabhan A, Raum JC, Li L, Morrisey EE, Lu MM, Won KJ, ... Epstein JA, et al. HEART DEVELOPMENT. Integration of Bmp and Wnt signaling by Hopx specifies commitment of cardiomyoblasts. Science (New York, N.Y.). 348: aaa6071. PMID 26113728 DOI: 10.1126/Science.Aaa6071 |
0.647 |
|
| 2015 |
Tomas-Roca L, Tsaalbi-Shtylik A, Jansen JG, Singh MK, Epstein JA, Altunoglu U, Verzijl H, Soria L, van Beusekom E, Roscioli T, Iqbal Z, Gilissen C, Hoischen A, de Brouwer AP, Erasmus C, et al. De novo mutations in PLXND1 and REV3L cause Möbius syndrome. Nature Communications. 6: 7199. PMID 26068067 DOI: 10.1038/Ncomms8199 |
0.324 |
|
| 2015 |
Zhou X, Crow AL, Hartiala J, Spindler TJ, Ghazalpour A, Barsky LW, Bennett BB, Parks BW, Eskin E, Jain R, Epstein JA, Lusis AJ, Adams GB, Allayee H. The Genetic Landscape of Hematopoietic Stem Cell Frequency in Mice. Stem Cell Reports. PMID 26050929 DOI: 10.1016/J.Stemcr.2015.05.008 |
0.347 |
|
| 2015 |
Jain R, Barkauskas CE, Takeda N, Bowie EJ, Aghajanian H, Wang Q, Padmanabhan A, Manderfield LJ, Gupta M, Li D, Li L, Trivedi CM, Hogan BL, Epstein JA. Plasticity of Hopx(+) type I alveolar cells to regenerate type II cells in the lung. Nature Communications. 6: 6727. PMID 25865356 DOI: 10.1038/Ncomms7727 |
0.573 |
|
| 2015 |
Epstein JA, Aghajanian H, Singh MK. Semaphorin signaling in cardiovascular development. Cell Metabolism. 21: 163-73. PMID 25651171 DOI: 10.1016/J.Cmet.2014.12.015 |
0.361 |
|
| 2015 |
Yzaguirre AD, Padmanabhan A, Groh EDd, Engleka KA, Li J, Speck NA, Epstein JA. Author response: Loss of neurofibromin Ras-GAP activity enhances the formation of cardiac blood islands in murine embryos Elife. DOI: 10.7554/Elife.07780.016 |
0.576 |
|
| 2014 |
Manderfield LJ, Engleka KA, Aghajanian H, Gupta M, Yang S, Li L, Baggs JE, Hogenesch JB, Olson EN, Epstein JA. Pax3 and hippo signaling coordinate melanocyte gene expression in neural crest. Cell Reports. 9: 1885-95. PMID 25466249 DOI: 10.1016/J.Celrep.2014.10.061 |
0.443 |
|
| 2014 |
Li N, Yousefi M, Nakauka-Ddamba A, Jain R, Tobias J, Epstein JA, Jensen ST, Lengner CJ. Single-cell analysis of proxy reporter allele-marked epithelial cells establishes intestinal stem cell hierarchy. Stem Cell Reports. 3: 876-91. PMID 25418730 DOI: 10.1016/J.Stemcr.2014.09.011 |
0.306 |
|
| 2014 |
Chen HI, Sharma B, Akerberg BN, Numi HJ, Kivelä R, Saharinen P, Aghajanian H, McKay AS, Bogard PE, Chang AH, Jacobs AH, Epstein JA, Stankunas K, Alitalo K, Red-Horse K. The sinus venosus contributes to coronary vasculature through VEGFC-stimulated angiogenesis. Development (Cambridge, England). 141: 4500-12. PMID 25377552 DOI: 10.1242/Dev.113639 |
0.327 |
|
| 2014 |
Aghajanian H, Choi C, Ho VC, Gupta M, Singh MK, Epstein JA. Semaphorin 3d and semaphorin 3e direct endothelial motility through distinct molecular signaling pathways. The Journal of Biological Chemistry. 289: 17971-9. PMID 24825896 DOI: 10.1074/Jbc.M113.544833 |
0.323 |
|
| 2014 |
Gerhardt DM, Pajcini KV, D'altri T, Tu L, Jain R, Xu L, Chen MJ, Rentschler S, Shestova O, Wertheim GB, Tobias JW, Kluk M, Wood AW, Aster JC, Gimotty PA, ... Epstein JA, et al. The Notch1 transcriptional activation domain is required for development and reveals a novel role for Notch1 signaling in fetal hematopoietic stem cells. Genes & Development. 28: 576-93. PMID 24637115 DOI: 10.1101/Gad.227496.113 |
0.42 |
|
| 2014 |
Ifkovits JL, Addis RC, Epstein JA, Gearhart JD. Inhibition of TGFβ signaling increases direct conversion of fibroblasts to induced cardiomyocytes. Plos One. 9: e89678. PMID 24586958 DOI: 10.1371/Journal.Pone.0089678 |
0.416 |
|
| 2014 |
Worzfeld T, Swiercz JM, Sentürk A, Genz B, Korostylev A, Deng S, Xia J, Hoshino M, Epstein JA, Chan AM, Vollmar B, Acker-Palmer A, Kuner R, Offermanns S. Genetic dissection of plexin signaling in vivo. Proceedings of the National Academy of Sciences of the United States of America. 111: 2194-9. PMID 24469813 DOI: 10.1073/Pnas.1308418111 |
0.36 |
|
| 2014 |
Zhao T, Gan Q, Stokes A, Lassiter RN, Wang Y, Chan J, Han JX, Pleasure DE, Epstein JA, Zhou CJ. β-catenin regulates Pax3 and Cdx2 for caudal neural tube closure and elongation. Development (Cambridge, England). 141: 148-57. PMID 24284205 DOI: 10.1242/Dev.101550 |
0.408 |
|
| 2013 |
Choi YI, Duke-Cohan JS, Tan J, Gui J, Singh MK, Epstein JA, Reinherz EL. Plxnd1 expression in thymocytes regulates their intrathymic migration while that in thymic endothelium impacts medullary topology. Frontiers in Immunology. 4: 392. PMID 24312099 DOI: 10.3389/Fimmu.2013.00392 |
0.406 |
|
| 2013 |
Addis RC, Epstein JA. Induced regeneration--the progress and promise of direct reprogramming for heart repair. Nature Medicine. 19: 829-36. PMID 23836233 DOI: 10.1038/Nm.3225 |
0.366 |
|
| 2013 |
Takeda N, Jain R, Li D, Li L, Lu MM, Epstein JA. Lgr5 Identifies Progenitor Cells Capable of Taste Bud Regeneration after Injury. Plos One. 8: e66314. PMID 23824276 DOI: 10.1371/Journal.Pone.0066314 |
0.322 |
|
| 2013 |
Addis RC, Ifkovits JL, Pinto F, Kellam LD, Esteso P, Rentschler S, Christoforou N, Epstein JA, Gearhart JD. Optimization of direct fibroblast reprogramming to cardiomyocytes using calcium activity as a functional measure of success. Journal of Molecular and Cellular Cardiology. 60: 97-106. PMID 23591016 DOI: 10.1016/J.Yjmcc.2013.04.004 |
0.315 |
|
| 2013 |
Singh N, Gupta M, Trivedi CM, Singh MK, Li L, Epstein JA. Murine craniofacial development requires Hdac3-mediated repression of Msx gene expression. Developmental Biology. 377: 333-44. PMID 23506836 DOI: 10.1016/J.Ydbio.2013.03.008 |
0.601 |
|
| 2013 |
Parmacek MS, Epstein JA. An epigenetic roadmap for cardiomyocyte differentiation. Circulation Research. 112: 881-3. PMID 23493303 DOI: 10.1161/Circresaha.113.301134 |
0.418 |
|
| 2013 |
Takeda N, Jain R, Leboeuf MR, Padmanabhan A, Wang Q, Li L, Lu MM, Millar SE, Epstein JA. Hopx expression defines a subset of multipotent hair follicle stem cells and a progenitor population primed to give rise to K6+ niche cells. Development (Cambridge, England). 140: 1655-64. PMID 23487314 DOI: 10.1242/Dev.093005 |
0.591 |
|
| 2013 |
Meadows SM, Ratliff LA, Singh MK, Epstein JA, Cleaver O. Resolution of defective dorsal aortae patterning in Sema3E-deficient mice occurs via angiogenic remodeling. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 242: 580-90. PMID 23444297 DOI: 10.1002/Dvdy.23949 |
0.333 |
|
| 2013 |
Degenhardt K, Singh MK, Epstein JA. New approaches under development: cardiovascular embryology applied to heart disease. The Journal of Clinical Investigation. 123: 71-4. PMID 23281412 DOI: 10.1172/Jci62884 |
0.33 |
|
| 2013 |
Padmanabhan A, Epstein JA. Zebrafish model for NF1 Neurofibromatosis Type 1: Molecular and Cellular Biology. 535-547. DOI: 10.1007/978-3-642-32864-0_35 |
0.477 |
|
| 2012 |
Yang Y, GarcÃa-Verdugo JM, Soriano-Navarro M, Srinivasan RS, Scallan JP, Singh MK, Epstein JA, Oliver G. Lymphatic endothelial progenitors bud from the cardinal vein and intersomitic vessels in mammalian embryos. Blood. 120: 2340-8. PMID 22859612 DOI: 10.1182/Blood-2012-05-428607 |
0.367 |
|
| 2012 |
Rentschler S, Yen AH, Lu J, Petrenko NB, Lu MM, Manderfield LJ, Patel VV, Fishman GI, Epstein JA. Myocardial Notch signaling reprograms cardiomyocytes to a conduction-like phenotype. Circulation. 126: 1058-66. PMID 22837163 DOI: 10.1161/Circulationaha.112.103390 |
0.394 |
|
| 2012 |
Shin J, Padmanabhan A, de Groh ED, Lee JS, Haidar S, Dahlberg S, Guo F, He S, Wolman MA, Granato M, Lawson ND, Wolfe SA, Kim SH, Solnica-Krezel L, Kanki JP, ... ... Epstein JA, et al. Zebrafish neurofibromatosis type 1 genes have redundant functions in tumorigenesis and embryonic development. Disease Models & Mechanisms. 5: 881-94. PMID 22773753 DOI: 10.1242/Dmm.009779 |
0.607 |
|
| 2012 |
Singh MK, Epstein JA. Epicardium-derived cardiac mesenchymal stem cells: expanding the outer limit of heart repair. Circulation Research. 110: 904-6. PMID 22461359 DOI: 10.1161/Res.0B013E31825332A3 |
0.428 |
|
| 2012 |
Katz TC, Singh MK, Degenhardt K, Rivera-Feliciano J, Johnson RL, Epstein JA, Tabin CJ. Distinct compartments of the proepicardial organ give rise to coronary vascular endothelial cells. Developmental Cell. 22: 639-50. PMID 22421048 DOI: 10.1016/J.Devcel.2012.01.012 |
0.37 |
|
| 2012 |
Engleka KA, Manderfield LJ, Brust RD, Li L, Cohen A, Dymecki SM, Epstein JA. Islet1 derivatives in the heart are of both neural crest and second heart field origin. Circulation Research. 110: 922-6. PMID 22394517 DOI: 10.1161/Circresaha.112.266510 |
0.428 |
|
| 2012 |
de la Pompa JL, Epstein JA. Coordinating tissue interactions: Notch signaling in cardiac development and disease. Developmental Cell. 22: 244-54. PMID 22340493 DOI: 10.1016/J.Devcel.2012.01.014 |
0.449 |
|
| 2012 |
Manderfield LJ, High FA, Engleka KA, Liu F, Li L, Rentschler S, Epstein JA. Notch activation of Jagged1 contributes to the assembly of the arterial wall. Circulation. 125: 314-23. PMID 22147907 DOI: 10.1161/Circulationaha.111.047159 |
0.688 |
|
| 2012 |
Boudou T, Legant WR, Mu A, Borochin MA, Thavandiran N, Radisic M, Zandstra PW, Epstein JA, Margulies KB, Chen CS. A microfabricated platform to measure and manipulate the mechanics of engineered cardiac microtissues. Tissue Engineering. Part A. 18: 910-9. PMID 22092279 DOI: 10.1089/Ten.Tea.2011.0341 |
0.321 |
|
| 2012 |
Epstein JA. Pax3, neural crest and cardiovascular development. Trends in Cardiovascular Medicine. 6: 255-60. PMID 21232305 DOI: 10.1016/S1050-1738(96)00110-7 |
0.419 |
|
| 2011 |
Takeda N, Jain R, LeBoeuf MR, Wang Q, Lu MM, Epstein JA. Interconversion between intestinal stem cell populations in distinct niches. Science (New York, N.Y.). 334: 1420-4. PMID 22075725 DOI: 10.1126/Science.1213214 |
0.313 |
|
| 2011 |
Singh MK, Lu MM, Massera D, Epstein JA. MicroRNA-processing enzyme Dicer is required in epicardium for coronary vasculature development. The Journal of Biological Chemistry. 286: 41036-45. PMID 21969379 DOI: 10.1074/Jbc.M111.268573 |
0.384 |
|
| 2011 |
Singh N, Trivedi CM, Lu M, Mullican SE, Lazar MA, Epstein JA. Histone deacetylase 3 regulates smooth muscle differentiation in neural crest cells and development of the cardiac outflow tract. Circulation Research. 109: 1240-9. PMID 21959220 DOI: 10.1161/Circresaha.111.255067 |
0.601 |
|
| 2011 |
Zhu C, Smith T, McNulty J, Rayla AL, Lakshmanan A, Siekmann AF, Buffardi M, Meng X, Shin J, Padmanabhan A, Cifuentes D, Giraldez AJ, Look AT, Epstein JA, Lawson ND, et al. Evaluation and application of modularly assembled zinc-finger nucleases in zebrafish. Development (Cambridge, England). 138: 4555-64. PMID 21937602 DOI: 10.1242/Dev.066779 |
0.574 |
|
| 2011 |
Li D, Epstein JA. Micro-managing myocyte mitosis. Circulation Research. 109: 611-3. PMID 21885834 DOI: 10.1161/Circresaha.111.252627 |
0.395 |
|
| 2011 |
Sun Z, Singh N, Mullican SE, Everett LJ, Li L, Yuan L, Liu X, Epstein JA, Lazar MA. Diet-induced lethality due to deletion of the Hdac3 gene in heart and skeletal muscle. The Journal of Biological Chemistry. 286: 33301-9. PMID 21808063 DOI: 10.1074/Jbc.M111.277707 |
0.566 |
|
| 2011 |
Zygmunt T, Gay CM, Blondelle J, Singh MK, Flaherty KM, Means PC, Herwig L, Krudewig A, Belting HG, Affolter M, Epstein JA, Torres-Vázquez J. Semaphorin-PlexinD1 signaling limits angiogenic potential via the VEGF decoy receptor sFlt1. Developmental Cell. 21: 301-14. PMID 21802375 DOI: 10.1016/J.Devcel.2011.06.033 |
0.302 |
|
| 2011 |
Lee T, Li YR, Chesi A, Hart MP, Ramos D, Jethava N, Hosangadi D, Epstein J, Hodges B, Bonini NM, Gitler AD. Evaluating the prevalence of polyglutamine repeat expansions in amyotrophic lateral sclerosis. Neurology. 76: 2062-5. PMID 21562248 DOI: 10.1212/Wnl.0B013E31821F4447 |
0.709 |
|
| 2011 |
Anokye-Danso F, Trivedi CM, Juhr D, Gupta M, Cui Z, Tian Y, Zhang Y, Yang W, Gruber PJ, Epstein JA, Morrisey EE. Highly efficient miRNA-mediated reprogramming of mouse and human somatic cells to pluripotency. Cell Stem Cell. 8: 376-88. PMID 21474102 DOI: 10.1016/J.Stem.2011.03.001 |
0.312 |
|
| 2011 |
Trivedi CM, Cappola TP, Margulies KB, Epstein JA. Homeodomain only protein x is down-regulated in human heart failure. Journal of Molecular and Cellular Cardiology. 50: 1056-8. PMID 21382376 DOI: 10.1016/J.Yjmcc.2011.02.015 |
0.391 |
|
| 2011 |
Rentschler S, Harris BS, Kuznekoff L, Jain R, Manderfield L, Lu MM, Morley GE, Patel VV, Epstein JA. Notch signaling regulates murine atrioventricular conduction and the formation of accessory pathways. The Journal of Clinical Investigation. 121: 525-33. PMID 21266778 DOI: 10.1172/Jci44470 |
0.397 |
|
| 2011 |
Rentschler S, Epstein JA. Kicking the epicardium up a notch. Circulation Research. 108: 6-8. PMID 21212389 DOI: 10.1161/Circresaha.110.237297 |
0.449 |
|
| 2011 |
Trivedi CM, Epstein JA. Heart-healthy hypertrophy. Cell Metabolism. 13: 3-4. PMID 21195341 DOI: 10.1016/J.Cmet.2010.12.012 |
0.365 |
|
| 2011 |
Jain R, Engleka KA, Rentschler SL, Manderfield LJ, Li L, Yuan L, Epstein JA. Cardiac neural crest orchestrates remodeling and functional maturation of mouse semilunar valves. The Journal of Clinical Investigation. 121: 422-30. PMID 21157040 DOI: 10.1172/Jci44244 |
0.34 |
|
| 2010 |
LeBoeuf M, Terrell A, Trivedi S, Sinha S, Epstein JA, Olson EN, Morrisey EE, Millar SE. Hdac1 and Hdac2 act redundantly to control p63 and p53 functions in epidermal progenitor cells. Developmental Cell. 19: 807-18. PMID 21093383 DOI: 10.1016/J.Devcel.2010.10.015 |
0.334 |
|
| 2010 |
Albrecht I, Niesner U, Janke M, Menning A, Loddenkemper C, Kühl AA, Lepenies I, Lexberg MH, Westendorf K, Hradilkova K, Grün J, Hamann A, Epstein JA, Chang HD, Tokoyoda K, et al. Persistence of effector memory Th1 cells is regulated by Hopx. European Journal of Immunology. 40: 2993-3006. PMID 21061432 DOI: 10.1002/Eji.201040936 |
0.317 |
|
| 2010 |
Epstein JA. Franklin H. Epstein Lecture. Cardiac development and implications for heart disease. The New England Journal of Medicine. 363: 1638-47. PMID 20961247 DOI: 10.1056/Nejmra1003941 |
0.359 |
|
| 2010 |
Lee JS, Padmanabhan A, Shin J, Zhu S, Guo F, Kanki JP, Epstein JA, Look AT. Oligodendrocyte progenitor cell numbers and migration are regulated by the zebrafish orthologs of the NF1 tumor suppressor gene. Human Molecular Genetics. 19: 4643-53. PMID 20858602 DOI: 10.1093/Hmg/Ddq395 |
0.592 |
|
| 2010 |
Trivedi CM, Zhu W, Wang Q, Jia C, Kee HJ, Li L, Hannenhalli S, Epstein JA. Hopx and Hdac2 interact to modulate Gata4 acetylation and embryonic cardiac myocyte proliferation. Developmental Cell. 19: 450-9. PMID 20833366 DOI: 10.1016/J.Devcel.2010.08.012 |
0.559 |
|
| 2010 |
Stoller JZ, Huang L, Tan CC, Huang F, Zhou DD, Yang J, Gelb BD, Epstein JA. Ash2l interacts with Tbx1 and is required during early embryogenesis. Experimental Biology and Medicine (Maywood, N.J.). 235: 569-76. PMID 20463296 DOI: 10.1258/Ebm.2010.009318 |
0.374 |
|
| 2010 |
Jain R, Rentschler S, Epstein JA. Notch and cardiac outflow tract development. Annals of the New York Academy of Sciences. 1188: 184-90. PMID 20201902 DOI: 10.1111/J.1749-6632.2009.05099.X |
0.437 |
|
| 2010 |
Degenhardt K, Wright AC, Horng D, Padmanabhan A, Epstein JA. Rapid 3D phenotyping of cardiovascular development in mouse embryos by micro-CT with iodine staining. Circulation. Cardiovascular Imaging. 3: 314-22. PMID 20190279 DOI: 10.1161/Circimaging.109.918482 |
0.585 |
|
| 2010 |
Chokas AL, Trivedi CM, Lu MM, Tucker PW, Li S, Epstein JA, Morrisey EE. Foxp1/2/4-NuRD interactions regulate gene expression and epithelial injury response in the lung via regulation of interleukin-6. The Journal of Biological Chemistry. 285: 13304-13. PMID 20185820 DOI: 10.1074/Jbc.M109.088468 |
0.344 |
|
| 2010 |
Degenhardt KR, Milewski RC, Padmanabhan A, Miller M, Singh MK, Lang D, Engleka KA, Wu M, Li J, Zhou D, Antonucci N, Li L, Epstein JA. Distinct enhancers at the Pax3 locus can function redundantly to regulate neural tube and neural crest expressions. Developmental Biology. 339: 519-27. PMID 20045680 DOI: 10.1016/J.Ydbio.2009.12.030 |
0.792 |
|
| 2010 |
Rentschler S, Jain R, Epstein JA. Tissue-tissue interactions during morphogenesis of the outflow tract. Pediatric Cardiology. 31: 408-13. PMID 20039033 DOI: 10.1007/S00246-009-9611-2 |
0.418 |
|
| 2010 |
Singh MK, Li Y, Li S, Cobb RM, Zhou D, Lu MM, Epstein JA, Morrisey EE, Gruber PJ. Gata4 and Gata5 cooperatively regulate cardiac myocyte proliferation in mice. The Journal of Biological Chemistry. 285: 1765-72. PMID 19889636 DOI: 10.1074/Jbc.M109.038539 |
0.459 |
|
| 2009 |
Padmanabhan A, Lee JS, Ismat FA, Lu MM, Lawson ND, Kanki JP, Look AT, Epstein JA. Cardiac and vascular functions of the zebrafish orthologues of the type I neurofibromatosis gene NFI. Proceedings of the National Academy of Sciences of the United States of America. 106: 22305-10. PMID 19966217 DOI: 10.1073/Pnas.0901932106 |
0.642 |
|
| 2009 |
Zhu W, Trivedi CM, Zhou D, Yuan L, Lu MM, Epstein JA. Inpp5f is a polyphosphoinositide phosphatase that regulates cardiac hypertrophic responsiveness. Circulation Research. 105: 1240-7. PMID 19875726 DOI: 10.1161/Circresaha.109.208785 |
0.559 |
|
| 2009 |
Levin MD, Lu MM, Petrenko NB, Hawkins BJ, Gupta TH, Lang D, Buckley PT, Jochems J, Liu F, Spurney CF, Yuan LJ, Jacobson JT, Brown CB, Huang L, Beermann F, ... ... Epstein JA, et al. Melanocyte-like cells in the heart and pulmonary veins contribute to atrial arrhythmia triggers. The Journal of Clinical Investigation. 119: 3420-36. PMID 19855129 DOI: 10.1172/Jci39109 |
0.402 |
|
| 2009 |
Xu J, Ismat FA, Wang T, Lu MM, Antonucci N, Epstein JA. Cardiomyocyte-specific loss of neurofibromin promotes cardiac hypertrophy and dysfunction. Circulation Research. 105: 304-11. PMID 19574548 DOI: 10.1161/Circresaha.109.201509 |
0.386 |
|
| 2009 |
High FA, Jain R, Stoller JZ, Antonucci NB, Lu MM, Loomes KM, Kaestner KH, Pear WS, Epstein JA. Murine Jagged1/Notch signaling in the second heart field orchestrates Fgf8 expression and tissue-tissue interactions during outflow tract development. The Journal of Clinical Investigation. 119: 1986-96. PMID 19509466 DOI: 10.1172/Jci38922 |
0.727 |
|
| 2009 |
Aziz A, Miyake T, Engleka KA, Epstein JA, McDermott JC. Menin expression modulates mesenchymal cell commitment to the myogenic and osteogenic lineages. Developmental Biology. 332: 116-30. PMID 19464283 DOI: 10.1016/J.Ydbio.2009.05.555 |
0.389 |
|
| 2009 |
Nishijo K, Hosoyama T, Bjornson CR, Schaffer BS, Prajapati SI, Bahadur AN, Hansen MS, Blandford MC, McCleish AT, Rubin BP, Epstein JA, Rando TA, Capecchi MR, Keller C. Biomarker system for studying muscle, stem cells, and cancer in vivo. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 2681-90. PMID 19332644 DOI: 10.1096/Fj.08-128116 |
0.351 |
|
| 2009 |
Griffith AV, Cardenas K, Carter C, Gordon J, Iberg A, Engleka K, Epstein JA, Manley NR, Richie ER. Increased thymus- and decreased parathyroid-fated organ domains in Splotch mutant embryos. Developmental Biology. 327: 216-27. PMID 19135046 DOI: 10.1016/J.Ydbio.2008.12.019 |
0.343 |
|
| 2009 |
Zhang Y, Singh MK, Degenhardt KR, Lu MM, Bennett J, Yoshida Y, Epstein JA. Tie2Cre-mediated inactivation of plexinD1 results in congenital heart, vascular and skeletal defects. Developmental Biology. 325: 82-93. PMID 18992737 DOI: 10.1016/J.Ydbio.2008.09.031 |
0.45 |
|
| 2008 |
Liu F, Levin MD, Petrenko NB, Lu MM, Wang T, Yuan LJ, Stout AL, Epstein JA, Patel VV. Histone-deacetylase inhibition reverses atrial arrhythmia inducibility and fibrosis in cardiac hypertrophy independent of angiotensin. Journal of Molecular and Cellular Cardiology. 45: 715-23. PMID 18926829 DOI: 10.1016/J.Yjmcc.2008.08.015 |
0.339 |
|
| 2008 |
Kerkela R, Kockeritz L, Macaulay K, Zhou J, Doble BW, Beahm C, Greytak S, Woulfe K, Trivedi CM, Woodgett JR, Epstein JA, Force T, Huggins GS. Deletion of GSK-3beta in mice leads to hypertrophic cardiomyopathy secondary to cardiomyoblast hyperproliferation. The Journal of Clinical Investigation. 118: 3609-18. PMID 18830417 DOI: 10.1172/Jci36245 |
0.384 |
|
| 2008 |
Trivedi CM, Lu MM, Wang Q, Epstein JA. Transgenic overexpression of Hdac3 in the heart produces increased postnatal cardiac myocyte proliferation but does not induce hypertrophy. The Journal of Biological Chemistry. 283: 26484-9. PMID 18625706 DOI: 10.1074/Jbc.M803686200 |
0.394 |
|
| 2008 |
Granger A, Abdullah I, Huebner F, Stout A, Wang T, Huebner T, Epstein JA, Gruber PJ. Histone deacetylase inhibition reduces myocardial ischemia-reperfusion injury in mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 3549-60. PMID 18606865 DOI: 10.1096/Fj.08-108548 |
0.305 |
|
| 2008 |
Lagha M, Kormish JD, Rocancourt D, Manceau M, Epstein JA, Zaret KS, Relaix F, Buckingham ME. Pax3 regulation of FGF signaling affects the progression of embryonic progenitor cells into the myogenic program. Genes & Development. 22: 1828-37. PMID 18593883 DOI: 10.1101/Gad.477908 |
0.433 |
|
| 2008 |
De Toni A, Zbinden M, Epstein JA, Ruiz i Altaba A, Prochiantz A, Caillé I. Regulation of survival in adult hippocampal and glioblastoma stem cell lineages by the homeodomain-only protein HOP. Neural Development. 3: 13. PMID 18507846 DOI: 10.1186/1749-8104-3-13 |
0.327 |
|
| 2008 |
Tan CC, Sindhu KV, Li S, Nishio H, Stoller JZ, Oishi K, Puttreddy S, Lee TJ, Epstein JA, Walsh MJ, Gelb BD. Transcription factor Ap2delta associates with Ash2l and ALR, a trithorax family histone methyltransferase, to activate Hoxc8 transcription. Proceedings of the National Academy of Sciences of the United States of America. 105: 7472-7. PMID 18495928 DOI: 10.1073/Pnas.0711896105 |
0.316 |
|
| 2008 |
Wu M, Li J, Engleka KA, Zhou B, Lu MM, Plotkin JB, Epstein JA. Persistent expression of Pax3 in the neural crest causes cleft palate and defective osteogenesis in mice. The Journal of Clinical Investigation. 118: 2076-87. PMID 18483623 DOI: 10.1172/Jci33715 |
0.445 |
|
| 2008 |
Stoller JZ, Degenhardt KR, Huang L, Zhou DD, Lu MM, Epstein JA. Cre reporter mouse expressing a nuclear localized fusion of GFP and beta-galactosidase reveals new derivatives of Pax3-expressing precursors. Genesis (New York, N.Y. : 2000). 46: 200-4. PMID 18395835 DOI: 10.1002/Dvg.20384 |
0.341 |
|
| 2008 |
Epstein JA. Currying favor for the heart. The Journal of Clinical Investigation. 118: 850-2. PMID 18292806 DOI: 10.1172/Jci34650 |
0.357 |
|
| 2008 |
High FA, Lu MM, Pear WS, Loomes KM, Kaestner KH, Epstein JA. Endothelial expression of the Notch ligand Jagged1 is required for vascular smooth muscle development. Proceedings of the National Academy of Sciences of the United States of America. 105: 1955-9. PMID 18245384 DOI: 10.1073/Pnas.0709663105 |
0.693 |
|
| 2008 |
Hori K, Cholewa-Waclaw J, Nakada Y, Glasgow SM, Masui T, Henke RM, Wildner H, Martarelli B, Beres TM, Epstein JA, Magnuson MA, Macdonald RJ, Birchmeier C, Johnson JE. A nonclassical bHLH Rbpj transcription factor complex is required for specification of GABAergic neurons independent of Notch signaling. Genes & Development. 22: 166-78. PMID 18198335 DOI: 10.1101/Gad.1628008 |
0.356 |
|
| 2008 |
Huang J, Cheng L, Li J, Chen M, Zhou D, Lu MM, Proweller A, Epstein JA, Parmacek MS. Myocardin regulates expression of contractile genes in smooth muscle cells and is required for closure of the ductus arteriosus in mice. The Journal of Clinical Investigation. 118: 515-25. PMID 18188448 DOI: 10.1172/Jci33304 |
0.389 |
|
| 2008 |
High FA, Epstein JA. The multifaceted role of Notch in cardiac development and disease. Nature Reviews. Genetics. 9: 49-61. PMID 18071321 DOI: 10.1038/Nrg2279 |
0.725 |
|
| 2008 |
Zhang Y, Yoshida Y, Lu M, Epstein JA. Endothelial deletion of PlexinD1 results in congenital heart, vascular and skeletal defects Developmental Biology. 319: 604. DOI: 10.1016/J.Ydbio.2008.05.444 |
0.331 |
|
| 2008 |
Xu J, Ismat FA, Wang T, Lu MM, Epstein JA. Cardiomyocyte-specific loss of neurofibromin promotes cardiac hypertrophy and dysfunction through activation of the fetal gene program Developmental Biology. 319: 525. DOI: 10.1016/J.Ydbio.2008.05.212 |
0.357 |
|
| 2008 |
Wu M, Li J, Engleka KA, Zhou B, Lu M, Plotkin J, Epstein JA. Persistent expression of Pax3 in neural crest causes cleft palate and defective osteogenesis Developmental Biology. 319: 500-501. DOI: 10.1016/J.Ydbio.2008.05.120 |
0.36 |
|
| 2007 |
High F, Epstein JA. Signalling pathways regulating cardiac neural crest migration and differentiation. Novartis Foundation Symposium. 283: 152-61; discussion 1. PMID 18300420 DOI: 10.1002/9780470319413.Ch12 |
0.725 |
|
| 2007 |
Xu J, Ismat FA, Wang T, Yang J, Epstein JA. NF1 regulates a Ras-dependent vascular smooth muscle proliferative injury response. Circulation. 116: 2148-56. PMID 17967772 DOI: 10.1161/Circulationaha.107.707752 |
0.363 |
|
| 2007 |
Engleka KA, Wu M, Zhang M, Antonucci NB, Epstein JA. Menin is required in cranial neural crest for palatogenesis and perinatal viability. Developmental Biology. 311: 524-37. PMID 17927973 DOI: 10.1016/J.Ydbio.2007.08.057 |
0.434 |
|
| 2007 |
Vasyutina E, Lenhard DC, Wende H, Erdmann B, Epstein JA, Birchmeier C. RBP-J (Rbpsuh) is essential to maintain muscle progenitor cells and to generate satellite cells. Proceedings of the National Academy of Sciences of the United States of America. 104: 4443-8. PMID 17360543 DOI: 10.1073/Pnas.0610647104 |
0.362 |
|
| 2007 |
Trivedi CM, Luo Y, Yin Z, Zhang M, Zhu W, Wang T, Floss T, Goettlicher M, Noppinger PR, Wurst W, Ferrari VA, Abrams CS, Gruber PJ, Epstein JA. Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3 beta activity. Nature Medicine. 13: 324-31. PMID 17322895 DOI: 10.1038/Nm1552 |
0.561 |
|
| 2007 |
High FA, Zhang M, Proweller A, Tu L, Parmacek MS, Pear WS, Epstein JA. An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation. The Journal of Clinical Investigation. 117: 353-63. PMID 17273555 DOI: 10.1172/Jci30070 |
0.751 |
|
| 2006 |
Luo Y, High FA, Epstein JA, Radice GL. N-cadherin is required for neural crest remodeling of the cardiac outflow tract. Developmental Biology. 299: 517-28. PMID 17014840 DOI: 10.1016/J.Ydbio.2006.09.003 |
0.715 |
|
| 2006 |
Hannenhalli S, Putt ME, Gilmore JM, Wang J, Parmacek MS, Epstein JA, Morrisey EE, Margulies KB, Cappola TP. Transcriptional genomics associates FOX transcription factors with human heart failure. Circulation. 114: 1269-76. PMID 16952980 DOI: 10.1161/Circulationaha.106.632430 |
0.365 |
|
| 2006 |
Kook H, Yung WW, Simpson RJ, Kee HJ, Shin S, Lowry JA, Loughlin FE, Yin Z, Epstein JA, Mackay JP. Analysis of the structure and function of the transcriptional coregulator HOP. Biochemistry. 45: 10584-90. PMID 16939210 DOI: 10.1021/Bi060641S |
0.33 |
|
| 2006 |
Ismat FA, Xu J, Lu MM, Epstein JA. The neurofibromin GAP-related domain rescues endothelial but not neural crest development in Nf1 mice. The Journal of Clinical Investigation. 116: 2378-84. PMID 16906226 DOI: 10.1172/Jci28341 |
0.373 |
|
| 2006 |
Liu S, Liu F, Schneider AE, St Amand T, Epstein JA, Gutstein DE. Distinct cardiac malformations caused by absence of connexin 43 in the neural crest and in the non-crest neural tube. Development (Cambridge, England). 133: 2063-73. PMID 16624854 DOI: 10.1242/Dev.02374 |
0.446 |
|
| 2006 |
Nowotschin S, Liao J, Gage PJ, Epstein JA, Campione M, Morrow BE. Tbx1 affects asymmetric cardiac morphogenesis by regulating Pitx2 in the secondary heart field. Development (Cambridge, England). 133: 1565-73. PMID 16556915 DOI: 10.1242/Dev.02309 |
0.43 |
|
| 2006 |
Yin Z, Gonzales L, Kolla V, Rath N, Zhang Y, Lu MM, Kimura S, Ballard PL, Beers MF, Epstein JA, Morrisey EE. Hop functions downstream of Nkx2.1 and GATA6 to mediate HDAC-dependent negative regulation of pulmonary gene expression. American Journal of Physiology. Lung Cellular and Molecular Physiology. 291: L191-9. PMID 16510470 DOI: 10.1152/Ajplung.00385.2005 |
0.406 |
|
| 2006 |
St Amand TR, Lu JT, Zamora M, Gu Y, Stricker J, Hoshijima M, Epstein JA, Ross JJ, Ruiz-Lozano P, Chien KR. Distinct roles of HF-1b/Sp4 in ventricular and neural crest cells lineages affect cardiac conduction system development. Developmental Biology. 291: 208-17. PMID 16430881 DOI: 10.1016/J.Ydbio.2005.10.018 |
0.419 |
|
| 2006 |
Schienda J, Engleka KA, Jun S, Hansen MS, Epstein JA, Tabin CJ, Kunkel LM, Kardon G. Somitic origin of limb muscle satellite and side population cells. Proceedings of the National Academy of Sciences of the United States of America. 103: 945-50. PMID 16418263 DOI: 10.1073/Pnas.0510164103 |
0.34 |
|
| 2006 |
Kee HJ, Sohn IS, Nam KI, Park JE, Qian YR, Yin Z, Ahn Y, Jeong MH, Bang YJ, Kim N, Kim JK, Kim KK, Epstein JA, Kook H. Inhibition of histone deacetylation blocks cardiac hypertrophy induced by angiotensin II infusion and aortic banding. Circulation. 113: 51-9. PMID 16380549 DOI: 10.1161/Circulationaha.105.559724 |
0.315 |
|
| 2006 |
Maillard I, High F, Shestova O, Dedhia P, Epstein JA, Pear WS. Notch Signaling Regulates Hematopoietic Stem Cell Homeostasis in the Fetal Liver through a Non-Cell-Autonomous Mechanism. Blood. 108: 440-440. DOI: 10.1182/Blood.V108.11.440.440 |
0.709 |
|
| 2005 |
Wynder C, Hakimi MA, Epstein JA, Shilatifard A, Shiekhattar R. Recruitment of MLL by HMG-domain protein iBRAF promotes neural differentiation. Nature Cell Biology. 7: 1113-7. PMID 16227968 DOI: 10.1038/Ncb1312 |
0.324 |
|
| 2005 |
Wang J, Sridurongrit S, Dudas M, Thomas P, Nagy A, Schneider MD, Epstein JA, Kaartinen V. Atrioventricular cushion transformation is mediated by ALK2 in the developing mouse heart. Developmental Biology. 286: 299-310. PMID 16140292 DOI: 10.1016/J.Ydbio.2005.07.035 |
0.428 |
|
| 2005 |
Ackerman KG, Herron BJ, Vargas SO, Huang H, Tevosian SG, Kochilas L, Rao C, Pober BR, Babiuk RP, Epstein JA, Greer JJ, Beier DR. Fog2 is required for normal diaphragm and lung development in mice and humans. Plos Genetics. 1: 58-65. PMID 16103912 DOI: 10.1371/Journal.Pgen.0010010 |
0.336 |
|
| 2005 |
Stoller JZ, Epstein JA. Cardiac neural crest. Seminars in Cell & Developmental Biology. 16: 704-15. PMID 16054405 DOI: 10.1016/J.Semcdb.2005.06.004 |
0.449 |
|
| 2005 |
Epstein JA, Parmacek MS. Recent advances in cardiac development with therapeutic implications for adult cardiovascular disease. Circulation. 112: 592-7. PMID 16043659 DOI: 10.1161/Circulationaha.104.479857 |
0.413 |
|
| 2005 |
Briegel KJ, Baldwin HS, Epstein JA, Joyner AL. Congenital heart disease reminiscent of partial trisomy 2p syndrome in mice transgenic for the transcription factor Lbh. Development (Cambridge, England). 132: 3305-16. PMID 15958514 DOI: 10.1242/Dev.01887 |
0.451 |
|
| 2005 |
Li J, Zhu X, Chen M, Cheng L, Zhou D, Lu MM, Du K, Epstein JA, Parmacek MS. Myocardin-related transcription factor B is required in cardiac neural crest for smooth muscle differentiation and cardiovascular development. Proceedings of the National Academy of Sciences of the United States of America. 102: 8916-21. PMID 15951419 DOI: 10.1073/Pnas.0503741102 |
0.439 |
|
| 2005 |
Engleka KA, Gitler AD, Zhang M, Zhou DD, High FA, Epstein JA. Insertion of Cre into the Pax3 locus creates a new allele of Splotch and identifies unexpected Pax3 derivatives. Developmental Biology. 280: 396-406. PMID 15882581 DOI: 10.1016/J.Ydbio.2005.02.002 |
0.774 |
|
| 2005 |
Abdullah I, Lepore JJ, Epstein JA, Parmacek MS, Gruber PJ. MRL mice fail to heal the heart in response to ischemia-reperfusion injury. Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. 13: 205-8. PMID 15828946 DOI: 10.1111/J.1067-1927.2005.130212.X |
0.315 |
|
| 2005 |
Ismat FA, Zhang M, Kook H, Huang B, Zhou R, Ferrari VA, Epstein JA, Patel VV. Homeobox protein Hop functions in the adult cardiac conduction system. Circulation Research. 96: 898-903. PMID 15790958 DOI: 10.1161/01.Res.0000163108.47258.F3 |
0.399 |
|
| 2005 |
Brown CB, Engleka KA, Wenning J, Min Lu M, Epstein JA. Identification of a hypaxial somite enhancer element regulating Pax3 expression in migrating myoblasts and characterization of hypaxial muscle Cre transgenic mice. Genesis (New York, N.Y. : 2000). 41: 202-9. PMID 15789408 DOI: 10.1002/Gene.20116 |
0.396 |
|
| 2005 |
Lang D, Lu MM, Huang L, Engleka KA, Zhang M, Chu EY, Lipner S, Skoultchi A, Millar SE, Epstein JA. Pax3 functions at a nodal point in melanocyte stem cell differentiation. Nature. 433: 884-7. PMID 15729346 DOI: 10.1038/Nature03292 |
0.368 |
|
| 2005 |
Parmacek MS, Epstein JA. Pursuing cardiac progenitors: regeneration redux. Cell. 120: 295-8. PMID 15707888 DOI: 10.1016/J.Cell.2005.01.025 |
0.405 |
|
| 2005 |
Stoller JZ, Epstein JA. Identification of a novel nuclear localization signal in Tbx1 that is deleted in DiGeorge syndrome patients harboring the 1223delC mutation. Human Molecular Genetics. 14: 885-92. PMID 15703190 DOI: 10.1093/Hmg/Ddi081 |
0.309 |
|
| 2004 |
Horwitz PA, Tsai EJ, Putt ME, Gilmore JM, Lepore JJ, Parmacek MS, Kao AC, Desai SS, Goldberg LR, Brozena SC, Jessup ML, Epstein JA, Cappola TP. Detection of cardiac allograft rejection and response to immunosuppressive therapy with peripheral blood gene expression. Circulation. 110: 3815-21. PMID 15583081 DOI: 10.1161/01.Cir.0000150539.72783.Bf |
0.307 |
|
| 2004 |
Araki T, Mohi MG, Ismat FA, Bronson RT, Williams IR, Kutok JL, Yang W, Pao LI, Gilliland DG, Epstein JA, Neel BG. Mouse model of Noonan syndrome reveals cell type- and gene dosage-dependent effects of Ptpn11 mutation. Nature Medicine. 10: 849-57. PMID 15273746 DOI: 10.1038/Nm1084 |
0.38 |
|
| 2004 |
Torres-Vázquez J, Gitler AD, Fraser SD, Berk JD, Van N Pham, Fishman MC, Childs S, Epstein JA, Weinstein BM. Semaphorin-plexin signaling guides patterning of the developing vasculature. Developmental Cell. 7: 117-23. PMID 15239959 DOI: 10.1016/J.Devcel.2004.06.008 |
0.562 |
|
| 2004 |
Gitler AD, Lu MM, Epstein JA. PlexinD1 and semaphorin signaling are required in endothelial cells for cardiovascular development. Developmental Cell. 7: 107-16. PMID 15239958 DOI: 10.1016/J.Devcel.2004.06.002 |
0.635 |
|
| 2004 |
Kaartinen V, Dudas M, Nagy A, Sridurongrit S, Lu MM, Epstein JA. Cardiac outflow tract defects in mice lacking ALK2 in neural crest cells. Development (Cambridge, England). 131: 3481-90. PMID 15226263 DOI: 10.1242/Dev.01214 |
0.487 |
|
| 2004 |
Liao J, Kochilas L, Nowotschin S, Arnold JS, Aggarwal VS, Epstein JA, Brown MC, Adams J, Morrow BE. Full spectrum of malformations in velo-cardio-facial syndrome/DiGeorge syndrome mouse models by altering Tbx1 dosage. Human Molecular Genetics. 13: 1577-85. PMID 15190012 DOI: 10.1093/Hmg/Ddh176 |
0.348 |
|
| 2004 |
Akiyama H, Chaboissier MC, Behringer RR, Rowitch DH, Schedl A, Epstein JA, De Crombrugghe B. Essential role of Sox9 in the pathway that controls formation of cardiac valves and septa Proceedings of the National Academy of Sciences of the United States of America. 101: 6502-6507. PMID 15096597 DOI: 10.1073/Pnas.0401711101 |
0.42 |
|
| 2004 |
Chang CP, McDill BW, Neilson JR, Joist HE, Epstein JA, Crabtree GR, Chen F. Calcineurin is required in urinary tract mesenchyme for the development of the pyeloureteral peristaltic machinery. The Journal of Clinical Investigation. 113: 1051-8. PMID 15057312 DOI: 10.1172/Jci20049 |
0.334 |
|
| 2004 |
Gruber PJ, Epstein JA. Development gone awry: congenital heart disease. Circulation Research. 94: 273-83. PMID 14976138 DOI: 10.1161/01.Res.0000116144.43797.3B |
0.333 |
|
| 2004 |
Brown CB, Wenning JM, Lu MM, Epstein DJ, Meyers EN, Epstein JA. Cre-mediated excision of Fgf8 in the Tbx1 expression domain reveals a critical role for Fgf8 in cardiovascular development in the mouse. Developmental Biology. 267: 190-202. PMID 14975726 DOI: 10.1016/J.Ydbio.2003.10.024 |
0.443 |
|
| 2004 |
Gitler AD, Kong Y, Choi JK, Zhu Y, Pear WS, Epstein JA. Tie2-Cre-induced inactivation of a conditional mutant Nf1 allele in mouse results in a myeloproliferative disorder that models juvenile myelomonocytic leukemia. Pediatric Research. 55: 581-4. PMID 14739366 DOI: 10.1203/01.Pdr.0000113462.98851.2E |
0.613 |
|
| 2004 |
Milewski RC, Chi NC, Li J, Brown C, Lu MM, Epstein JA. Identification of minimal enhancer elements sufficient for Pax3 expression in neural crest and implication of Tead2 as a regulator of Pax3. Development (Cambridge, England). 131: 829-37. PMID 14736747 DOI: 10.1242/Dev.00975 |
0.782 |
|
| 2004 |
Kook H, Epstein JA. Hopping to the beat. Hop regulation of cardiac gene expression. Trends in Cardiovascular Medicine. 13: 261-4. PMID 14522464 DOI: 10.1016/S1050-1738(03)00107-5 |
0.438 |
|
| 2004 |
Lang D, Epstein JA. Sox10 and Pax3 physically interact to mediate activation of a conserved c-RET enhancer. Human Molecular Genetics. 12: 937-45. PMID 12668617 DOI: 10.1093/Hmg/Ddg107 |
0.377 |
|
| 2004 |
Brown CB, Wenning JM, Lu MM, Epstein DJ, Meyers EN, Epstein JA. Corrigendum to “Cre-mediated excision of Fgf8 in the Tbx1 expression domain reveals a critical role for Fgf8 in cardiovascular development in the mouse” [Dev. Biol. 267 (2004) 190–202] Developmental Biology. 271: 223. DOI: 10.1016/J.Ydbio.2004.04.002 |
0.319 |
|
| 2003 |
Gitler AD, Lu MM, Jiang YQ, Epstein JA, Gruber PJ. Molecular markers of cardiac endocardial cushion development. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 228: 643-50. PMID 14648841 DOI: 10.1002/Dvdy.10418 |
0.655 |
|
| 2003 |
Epstein JA, Neel BG. An eye on organ development Nature. 426: 238-239. PMID 14628032 DOI: 10.1038/426238A |
0.328 |
|
| 2003 |
Katz SG, Williams A, Yang J, Fujiwara Y, Tsang AP, Epstein JA, Orkin SH. Endothelial lineage-mediated loss of the GATA cofactor Friend of GATA 1 impairs cardiac development. Proceedings of the National Academy of Sciences of the United States of America. 100: 14030-5. PMID 14614148 DOI: 10.1073/Pnas.1936250100 |
0.477 |
|
| 2003 |
Lang D, Brown CB, Milewski R, Jiang YQ, Lu MM, Epstein JA. Distinct enhancers regulate neural expression of Pax7 Genomics. 82: 553-560. PMID 14559212 DOI: 10.1016/S0888-7543(03)00178-2 |
0.768 |
|
| 2003 |
Kook H, Lepore JJ, Gitler AD, Lu MM, Wing-Man Yung W, Mackay J, Zhou R, Ferrari V, Gruber P, Epstein JA. Cardiac hypertrophy and histone deacetylase-dependent transcriptional repression mediated by the atypical homeodomain protein Hop. The Journal of Clinical Investigation. 112: 863-71. PMID 12975471 DOI: 10.1172/Jci19137 |
0.631 |
|
| 2003 |
Gitler AD, Epstein JA. Regulating heart development: the role of Nf1. Cell Cycle (Georgetown, Tex.). 2: 96-8. PMID 12695655 DOI: 10.4161/Cc.2.2.299 |
0.633 |
|
| 2003 |
Gitler AD, Zhu Y, Ismat FA, Lu MM, Yamauchi Y, Parada LF, Epstein JA. Nf1 has an essential role in endothelial cells. Nature Genetics. 33: 75-9. PMID 12469121 DOI: 10.1038/Ng1059 |
0.646 |
|
| 2002 |
Gitler AD, Brown CB, Kochilas L, Li J, Epstein JA. Neural crest migration and mouse models of congenital heart disease. Cold Spring Harbor Symposia On Quantitative Biology. 67: 57-62. PMID 12858524 DOI: 10.1101/Sqb.2002.67.57 |
0.607 |
|
| 2002 |
Kochilas L, Merscher-Gomez S, Lu MM, Potluri V, Liao J, Kucherlapati R, Morrow B, Epstein JA. The role of neural crest during cardiac development in a mouse model of DiGeorge syndrome. Developmental Biology. 251: 157-66. PMID 12413905 DOI: 10.1006/Dbio.2002.0819 |
0.471 |
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| 2002 |
Chen F, Kook H, Milewski R, Gitler AD, Lu MM, Li J, Nazarian R, Schnepp R, Jen K, Biben C, Runke G, Mackay JP, Novotny J, Schwartz RJ, Harvey RP, ... ... Epstein JA, et al. Hop is an unusual homeobox gene that modulates cardiac development. Cell. 110: 713-23. PMID 12297045 DOI: 10.1016/S0092-8674(02)00932-7 |
0.801 |
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| 2002 |
Glaser R, Lu MM, Narula N, Epstein JA. Smooth muscle cells, but not myocytes, of host origin in transplanted human hearts. Circulation. 106: 17-9. PMID 12093763 DOI: 10.1161/01.Cir.0000021923.58307.8F |
0.34 |
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| 2002 |
Epstein JA, Rader DJ, S.parmacek M. Perspective: Cardiovascular disease in the postgenomic era - Lessons learned and challenges ahead Endocrinology. 143: 2045-2050. PMID 12021168 DOI: 10.1210/Endo.143.6.8910 |
0.337 |
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| 2002 |
Chi N, Epstein JA. Getting your Pax straight: Pax proteins in development and disease. Trends in Genetics : Tig. 18: 41-7. PMID 11750700 DOI: 10.1016/S0168-9525(01)02594-X |
0.407 |
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| 2001 |
Kudoh T, Tsang M, Hukriede NA, Chen X, Dedekian M, Clarke CJ, Kiang A, Schultz S, Epstein JA, Toyama R, Dawid IB. A gene expression screen in zebrafish embryogenesis. Genome Research. 11: 1979-87. PMID 11731487 DOI: 10.1101/Gr.209601 |
0.31 |
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| 2001 |
Funke B, Epstein JA, Kochilas LK, Lu MM, Pandita RK, Liao J, Bauerndistel R, Schüler T, Schorle H, Brown MC, Adams J, Morrow BE. Mice overexpressing genes from the 22q11 region deleted in velo-cardio-facial syndrome/DiGeorge syndrome have middle and inner ear defects Human Molecular Genetics. 10: 2549-2556. PMID 11709542 DOI: 10.1093/Hmg/10.22.2549 |
0.329 |
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| 2001 |
Epstein JA. Developing models of DiGeorge syndrome. Trends in Genetics : Tig. 17: S13-7. PMID 11585671 DOI: 10.1016/S0168-9525(01)02450-7 |
0.353 |
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| 2001 |
Chen F, Collin GB, Liu KC, Beier DR, Eccles M, Nishina PM, Moshang T, Epstein JA. Characterization of the murine Lbx2 promoter, identification of the human homologue, and evaluation as a candidate for Alström syndrome. Genomics. 74: 219-27. PMID 11386758 DOI: 10.1006/Geno.2001.6539 |
0.348 |
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| 2001 |
Merscher S, Funke B, Epstein JA, Heyer J, Puech A, Lu MM, Xavier RJ, Demay MB, Russell RG, Factor S, Tokooya K, Jore BS, Lopez M, Pandita RK, Lia M, et al. TBX1 is responsible for cardiovascular defects in velo-cardio-facial/DiGeorge syndrome. Cell. 104: 619-29. PMID 11239417 DOI: 10.1016/S0092-8674(01)00247-1 |
0.344 |
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| 2001 |
Marmorstein LY, Kinev AV, Chan GKT, Bochar DA, Beniya H, Epstein JA, Yen TJ, Shiekhattar R. A human BRCA2 complex containing a structural DNA binding component influences cell cycle progression Cell. 104: 247-257. PMID 11207365 DOI: 10.1016/S0092-8674(01)00209-4 |
0.313 |
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| 2001 |
Loftin CD, Trivedi DB, Tiano HF, Clark JA, Lee CA, Epstein JA, Morham SG, Breyer MD, Nguyen M, Hawkins BM, Goulet JL, Smithies O, Koller BH, Langenbach R. Failure of ductus arteriosus closure and remodeling in neonatal mice deficient in cyclooxygenase-1 and cyclooxygenase-2. Proceedings of the National Academy of Sciences of the United States of America. 98: 1059-64. PMID 11158594 DOI: 10.1073/Pnas.98.3.1059 |
0.323 |
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| 2000 |
Lu MM, Chen F, Gitler A, Li J, Jin F, Ma XK, Epstein JA. Cloning and expression analysis of murine lupin, a member of a novel gene family that is conserved through evolution and associated with Lupus inclusions Development Genes and Evolution. 210: 512-517. PMID 11180800 DOI: 10.1007/S004270000093 |
0.606 |
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| 2000 |
Epstein JA, Buck CA. Transcriptional regulation of cardiac development: implications for congenital heart disease and DiGeorge syndrome. Pediatric Research. 48: 717-24. PMID 11102536 DOI: 10.1203/00006450-200012000-00003 |
0.396 |
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| 2000 |
Epstein JA. Developmental cardiology comes of age. Circulation Research. 87: 833-4. PMID 11073875 DOI: 10.1161/01.Res.87.10.833 |
0.437 |
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| 2000 |
Lang D, Chen F, Milewski R, Li J, Lu MM, Epstein JA. Pax3 is required for enteric ganglia formation and functions with Sox10 to modulate expression of c-ret Journal of Clinical Investigation. 106: 963-971. PMID 11032856 DOI: 10.1172/Jci10828 |
0.751 |
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| 2000 |
Epstein JA. Pax3 and vertebrate development Methods in Molecular Biology (Clifton, N.J.). 137: 459-470. PMID 10948560 DOI: 10.1385/1-59259-066-7:459 |
0.308 |
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| 2000 |
Galili N, Nayak S, Epstein JA, Buck CA. Rnf4, a RING protein expressed in the developing nervous and reproductive systems, interacts with Gscl, a gene within the DiGeorge critical region. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 218: 102-11. PMID 10822263 DOI: 10.1002/(Sici)1097-0177(200005)218:1<102::Aid-Dvdy9>3.0.Co;2-A |
0.373 |
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| 2000 |
Li J, Chen F, Epstein JA. Neural crest expression of Cre recombinase directed by the proximal Pax3 promoter in transgenic mice. Genesis (New York, N.Y. : 2000). 26: 162-4. PMID 10686619 DOI: 10.1002/(Sici)1526-968X(200002)26:2<162::Aid-Gene21>3.0.Co;2-R |
0.358 |
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| 1999 |
Chen F, Liu KC, Epstein JA. Lbx2, a novel murine homeobox gene related to the Drosophila ladybird genes is expressed in the developing urogenital system, eye and brain. Mechanisms of Development. 84: 181-184. PMID 10473138 DOI: 10.1016/S0925-4773(99)00073-8 |
0.337 |
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| 1999 |
Lakkis MM, Golden JA, O'Shea KS, Epstein JA. Neurofibromin deficiency in mice causes exencephaly and is a modifier for Splotch neural tube defects. Developmental Biology. 212: 80-92. PMID 10419687 DOI: 10.1006/Dbio.1999.9327 |
0.409 |
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| 1999 |
Kochilas LK, Li J, Jin F, Buck CA, Epstein JA. p57Kip2 expression is enhanced during mid-cardiac murine development and is restricted to trabecular myocardium. Pediatric Research. 45: 635-42. PMID 10231856 DOI: 10.1203/00006450-199905010-00004 |
0.471 |
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| 1998 |
Epstein JA, Song B, Lakkis M, Wang C. Tumor-specific PAX3-FKHR transcription factor, but not PAX3, activates the platelet-derived growth factor alpha receptor. Molecular and Cellular Biology. 18: 4118-30. PMID 9632796 DOI: 10.1128/Mcb.18.7.4118 |
0.321 |
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| 1998 |
Galili N, Epstein JA, Leconte I, Nayak S, Buck CA. Gscl, a gene within the minimal DiGeorge critical region, is expressed in primordial germ cells and the developing pons. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 212: 86-93. PMID 9603426 DOI: 10.1002/(Sici)1097-0177(199805)212:1<86::Aid-Aja8>3.0.Co;2-Z |
0.369 |
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| 1998 |
St John Sutton M, Epstein JA. Hypertrophic cardiomyopathy--beyond the sarcomere. The New England Journal of Medicine. 338: 1303-4. PMID 9562586 DOI: 10.1056/Nejm199804303381810 |
0.361 |
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| 1998 |
Kochilas LK, Buck CA, Epstein JA. Identification of Genes involved in Cardiac Development • 120 Pediatric Research. 43: 23-23. DOI: 10.1203/00006450-199804001-00141 |
0.408 |
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| 1997 |
Xu PX, Cheng J, Epstein JA, Maas RL. Mouse Eya genes are expressed during limb tendon development and encode a transcriptional activation function. Proceedings of the National Academy of Sciences of the United States of America. 94: 11974-9. PMID 9342347 DOI: 10.1073/Pnas.94.22.11974 |
0.393 |
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| 1996 |
Epstein JA, Shapiro DN, Cheng J, Lam PY, Maas RL. Pax3 modulates expression of the c-Met receptor during limb muscle development. Proceedings of the National Academy of Sciences of the United States of America. 93: 4213-8. PMID 8633043 DOI: 10.1073/Pnas.93.9.4213 |
0.365 |
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| 1995 |
Epstein JA, Lam P, Jepeal L, Maas RL, Shapiro DN. Pax3 inhibits myogenic differentiation of cultured myoblast cells. The Journal of Biological Chemistry. 270: 11719-22. PMID 7744814 DOI: 10.1074/Jbc.270.20.11719 |
0.361 |
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