Irma Thesleff - Publications

Affiliations: 
University of Helsinki, Helsingfors, Finland 

200 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Järvinen E, Shimomura-Kuroki J, Balic A, Jussila M, Thesleff I. Mesenchymal Wnt/β-catenin signaling limits tooth number. Development (Cambridge, England). PMID 29437780 DOI: 10.1242/Dev.158048  0.68
2015 Jussila M, Aalto A, Navarro MS, Shirokova V, Balic A, Kallonen A, Ohyama T, Groves A, Mikkola ML, Thesleff I. Suppression of epithelial differentiation by Foxi3 is essential for molar crown patterning. Development (Cambridge, England). PMID 26450968 DOI: 10.1242/Dev.124172  1
2015 Yang Z, Balic A, Michon F, Juuri E, Thesleff I. Mesenchymal Wnt/β-Catenin Signaling Controls Epithelial Stem Cell Homeostasis in Teeth by Inhibiting the Antiapoptotic Effect of Fgf10. Stem Cells (Dayton, Ohio). 33: 1670-81. PMID 25693510 DOI: 10.1002/Stem.1972  1
2015 Heikinheimo K, Kurppa KJ, Laiho A, Peltonen S, Berdal A, Bouattour A, Ruhin B, Catón J, Thesleff I, Leivo I, Morgan PR. Early dental epithelial transcription factors distinguish ameloblastoma from keratocystic odontogenic tumor. Journal of Dental Research. 94: 101-11. PMID 25398365 DOI: 10.1177/0022034514556815  1
2014 Kaukua N, Shahidi MK, Konstantinidou C, Dyachuk V, Kaucka M, Furlan A, An Z, Wang L, Hultman I, Ahrlund-Richter L, Blom H, Brismar H, Lopes NA, Pachnis V, Suter U, ... ... Thesleff I, et al. Glial origin of mesenchymal stem cells in a tooth model system. Nature. 513: 551-4. PMID 25079316 DOI: 10.1038/Nature13536  1
2014 Thesleff I. Introduction to the ECR special odontology issue. Experimental Cell Research. 325: 57. PMID 24747302 DOI: 10.1016/J.Yexcr.2014.04.008  1
2014 Ahtiainen L, Lefebvre S, Lindfors PH, Renvoisé E, Shirokova V, Vartiainen MK, Thesleff I, Mikkola ML. Directional cell migration, but not proliferation, drives hair placode morphogenesis. Developmental Cell. 28: 588-602. PMID 24636260 DOI: 10.1016/J.Devcel.2014.02.003  1
2014 Thesleff I, Mikkola ML. Development of ectodermal organs. Seminars in Cell & Developmental Biology. 25: 1-2. PMID 24508683 DOI: 10.1016/J.Semcdb.2014.02.002  1
2014 Jussila M, Crespo Yanez X, Thesleff I. Initiation of teeth from the dental lamina in the ferret. Differentiation; Research in Biological Diversity. 87: 32-43. PMID 24393477 DOI: 10.1016/J.Diff.2013.11.004  1
2014 Thesleff I. Current understanding of the process of tooth formation: transfer from the laboratory to the clinic. Australian Dental Journal. 59: 48-54. PMID 24236691 DOI: 10.1111/Adj.12102  1
2014 Thesleff I. Molecular Genetics of Tooth Development Principles of Developmental Genetics: Second Edition. 393-405. DOI: 10.1016/B978-0-12-405945-0.00022-3  1
2014 Thesleff I, Juuri E. Dental Epithelial Stem Cells Stem Cell Biology and Tissue Engineering in Dental Sciences. 263-270. DOI: 10.1016/B978-0-12-397157-9.00021-7  1
2013 Juuri E, Isaksson S, Jussila M, Heikinheimo K, Thesleff I. Expression of the stem cell marker, SOX2, in ameloblastoma and dental epithelium. European Journal of Oral Sciences. 121: 509-16. PMID 24148099 DOI: 10.1111/Eos.12095  1
2013 Juuri E, Jussila M, Seidel K, Holmes S, Wu P, Richman J, Heikinheimo K, Chuong CM, Arnold K, Hochedlinger K, Klein O, Michon F, Thesleff I. Sox2 marks epithelial competence to generate teeth in mammals and reptiles. Development (Cambridge, England). 140: 1424-32. PMID 23462476 DOI: 10.1242/Dev.089599  1
2013 Shirokova V, Jussila M, Hytönen MK, Perälä N, Drögemüller C, Leeb T, Lohi H, Sainio K, Thesleff I, Mikkola ML. Expression of Foxi3 is regulated by ectodysplasin in skin appendage placodes. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 242: 593-603. PMID 23441037 DOI: 10.1002/Dvdy.23952  1
2013 Thesleff I, Juuri E. Tooth Development Mineralized Tissues in Oral and Craniofacial Science: Biological Principles and Clinical Correlates. 117-127. DOI: 10.1002/9781118704868.ch14  1
2013 Jussila M, Juuri E, Thesleff I. Tooth Morphogenesis and Renewal Stem Cells in Craniofacial Development and Regeneration. 109-134. DOI: 10.1002/9781118498026.ch6  1
2013 Huang GTJ, Thesleff I. Preface Stem Cells in Craniofacial Development and Regeneration. xv-xvi. DOI: 10.1002/9781118498026  1
2012 Jernvall J, Thesleff I. Tooth shape formation and tooth renewal: Evolving with the same signals Development (Cambridge). 139: 3487-3497. PMID 22949612 DOI: 10.1242/Dev.085084  1
2012 Häärä O, Harjunmaa E, Lindfors PH, Huh SH, Fliniaux I, Åberg T, Jernvall J, Ornitz DM, Mikkola ML, Thesleff I. Ectodysplasin regulates activator-inhibitor balance in murine tooth development through fgf20 signaling Development (Cambridge). 139: 3189-3199. PMID 22833125 DOI: 10.1242/Dev.079558  1
2012 Juuri E, Saito K, Ahtiainen L, Seidel K, Tummers M, Hochedlinger K, Klein OD, Thesleff I, Michon F. Sox2+ stem cells contribute to all epithelial lineages of the tooth via Sfrp5+ progenitors. Developmental Cell. 23: 317-28. PMID 22819339 DOI: 10.1016/J.Devcel.2012.05.012  1
2012 Närhi K, Tummers M, Ahtiainen L, Itoh N, Thesleff I, Mikkola ML. Sostdc1 defines the size and number of skin appendage placodes. Developmental Biology. 364: 149-61. PMID 22509524 DOI: 10.1016/J.Ydbio.2012.01.026  1
2012 Jussila M, Thesleff I. Signaling networks regulating tooth organogenesis and regeneration, and the specification of dental mesenchymal and epithelial cell lineages. Cold Spring Harbor Perspectives in Biology. 4: a008425. PMID 22415375 DOI: 10.1101/Cshperspect.A008425  1
2011 Nieminen P, Morgan NV, Fenwick AL, Parmanen S, Veistinen L, Mikkola ML, van der Spek PJ, Giraud A, Judd L, Arte S, Brueton LA, Wall SA, Mathijssen IM, Maher ER, Wilkie AO, ... ... Thesleff I, et al. Inactivation of IL11 signaling causes craniosynostosis, delayed tooth eruption, and supernumerary teeth. American Journal of Human Genetics. 89: 67-81. PMID 21741611 DOI: 10.1016/J.Ajhg.2011.05.024  1
2011 Häärä O, Fujimori S, Schmidt-Ullrich R, Hartmann C, Thesleff I, Mikkola ML. Ectodysplasin and Wnt pathways are required for salivary gland branching morphogenesis. Development (Cambridge, England). 138: 2681-91. PMID 21652647 DOI: 10.1242/Dev.057711  1
2010 Yoshida T, Miyoshi J, Takai Y, Thesleff I. Cooperation of nectin-1 and nectin-3 is required for normal ameloblast function and crown shape development in mouse teeth. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 239: 2558-69. PMID 21038445 DOI: 10.1002/Dvdy.22395  1
2010 Fujimori S, Novak H, Weissenböck M, Jussila M, Gonçalves A, Zeller R, Galloway J, Thesleff I, Hartmann C. Wnt/β-catenin signaling in the dental mesenchyme regulates incisor development by regulating Bmp4. Developmental Biology. 348: 97-106. PMID 20883686 DOI: 10.1016/J.Ydbio.2010.09.009  1
2010 Närhi K, Thesleff I. Explant culture of embryonic craniofacial tissues: analyzing effects of signaling molecules on gene expression. Methods in Molecular Biology (Clifton, N.J.). 666: 253-67. PMID 20717789 DOI: 10.1007/978-1-60761-820-1_16  1
2010 Felszeghy S, Suomalainen M, Thesleff I. Notch signalling is required for the survival of epithelial stem cells in the continuously growing mouse incisor. Differentiation; Research in Biological Diversity. 80: 241-8. PMID 20692087 DOI: 10.1016/J.Diff.2010.06.004  1
2010 Munne PM, Felszeghy S, Jussila M, Suomalainen M, Thesleff I, Jernvall J. Splitting placodes: Effects of bone morphogenetic protein and Activin on the patterning and identity of mouse incisors Evolution and Development. 12: 383-392. PMID 20618434 DOI: 10.1111/J.1525-142X.2010.00425.X  1
2010 Michon F, Tummers M, Kyyrönen M, Frilander MJ, Thesleff I. Tooth morphogenesis and ameloblast differentiation are regulated by micro-RNAs. Developmental Biology. 340: 355-68. PMID 20102707 DOI: 10.1016/J.Ydbio.2010.01.019  1
2010 Mikkola ML, Costanzo A, Thesleff I, Roop DR, Koster MI. Treasure or artifact: a decade of p63 research speaks for itself. Cell Death and Differentiation. 17: 180-3; author reply . PMID 19876067 DOI: 10.1038/Cdd.2009.157  1
2010 Suomalainen M, Thesleff I. Patterns of Wnt pathway activity in the mouse incisor indicate absence of Wnt/beta-catenin signaling in the epithelial stem cells. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 239: 364-72. PMID 19806668 DOI: 10.1002/Dvdy.22106  1
2010 Thesleff I. The Teeth Embryos, Genes and Birth Defects: Second Edition. 515-535. DOI: 10.1002/9780470090121.ch17  1
2009 Takatalo MS, Tummers M, Thesleff I, Rönnholm R. Novel Golgi protein, GoPro49, is a specific dental follicle marker. Journal of Dental Research. 88: 534-8. PMID 19587158 DOI: 10.1177/0022034509338452  1
2009 Tummers M, Thesleff I. The importance of signal pathway modulation in all aspects of tooth development. Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution. 312: 309-19. PMID 19156667 DOI: 10.1002/Jez.B.21280  1
2009 Munne PM, Tummers M, Järvinen E, Thesleff I, Jernvall J. Tinkering with the inductive mesenchyme: Sostdc1 uncovers the role of dental mesenchyme in limiting tooth induction Development. 136: 393-402. PMID 19141669 DOI: 10.1242/Dev.025064  1
2009 Järvinen E, Tummers M, Thesleff I. The role of the dental lamina in mammalian tooth replacement. Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution. 312: 281-91. PMID 19137538 DOI: 10.1002/Jez.B.21275  1
2009 Charoenchaikorn K, Yokomizo T, Rice DP, Honjo T, Matsuzaki K, Shintaku Y, Imai Y, Wakamatsu A, Takahashi S, Ito Y, Takano-Yamamoto T, Thesleff I, Yamamoto M, Yamashiro T. Runx1 is involved in the fusion of the primary and the secondary palatal shelves. Developmental Biology. 326: 392-402. PMID 19000669 DOI: 10.1016/J.Ydbio.2008.10.018  1
2009 Charoenchaikorn K, Yokomizo T, Rice DP, Honjo T, Matsuzaki K, Shintaku Y, Imai Y, Wakamatsu A, Takahashi S, Ito Y, Takano-Yamamoto T, Thesleff I, Yamamoto M, Yamashiro T. Corrigendum to "Runx1 is involved in the fusion of the primary and the secondary palatal shelves" [Dev. Biol. 326 (2009) 392-402] (DOI:10.1016/j.ydbio.2008.10.018) Developmental Biology. 335: 464. DOI: 10.1016/J.Ydbio.2009.09.017  1
2008 Thesleff I, Sahlberg C. Organ culture in the analysis of tissue interactions. Methods in Molecular Biology (Clifton, N.J.). 461: 23-30. PMID 19030788 DOI: 10.1007/978-1-60327-483-8_3  1
2008 Pispa J, Pummila M, Barker PA, Thesleff I, Mikkola ML. Edar and Troy signalling pathways act redundantly to regulate initiation of hair follicle development. Human Molecular Genetics. 17: 3380-91. PMID 18689798 DOI: 10.1093/Hmg/Ddn232  1
2008 Takatalo M, Järvinen E, Laitinen S, Thesleff I, Rönnholm R. Expression of the novel Golgi protein GoPro49 is developmentally regulated during mesenchymal differentiation. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 237: 2243-55. PMID 18651652 DOI: 10.1002/Dvdy.21646  1
2008 Järvinen E, Välimäki K, Pummila M, Thesleff I, Jernvall J. The taming of the shrew milk teeth Evolution and Development. 10: 477-486. PMID 18638324 DOI: 10.1111/J.1525-142X.2008.00258.X  1
2008 Zhang FP, Mikkonen L, Toppari J, Palvimo JJ, Thesleff I, Jänne OA. Sumo-1 function is dispensable in normal mouse development. Molecular and Cellular Biology. 28: 5381-90. PMID 18573887 DOI: 10.1128/Mcb.00651-08  1
2008 Fliniaux I, Mikkola ML, Lefebvre S, Thesleff I. Identification of dkk4 as a target of Eda-A1/Edar pathway reveals an unexpected role of ectodysplasin as inhibitor of Wnt signalling in ectodermal placodes. Developmental Biology. 320: 60-71. PMID 18508042 DOI: 10.1016/J.Ydbio.2008.04.023  1
2008 Tummers M, Thesleff I. Observations on continuously growing roots of the sloth and the K14-Eda transgenic mice indicate that epithelial stem cells can give rise to both the ameloblast and root epithelium cell lineage creating distinct tooth patterns. Evolution & Development. 10: 187-95. PMID 18315812 DOI: 10.1111/J.1525-142X.2008.00226.X  1
2008 Närhi K, Järvinen E, Birchmeier W, Taketo MM, Mikkola ML, Thesleff I. Sustained epithelial beta-catenin activity induces precocious hair development but disrupts hair follicle down-growth and hair shaft formation. Development (Cambridge, England). 135: 1019-28. PMID 18256193 DOI: 10.1242/Dev.016550  1
2007 Tummers M, Yamashiro T, Thesleff I. Modulation of epithelial cell fate of the root in vitro. Journal of Dental Research. 86: 1063-7. PMID 17959897 DOI: 10.1177/154405910708601108  1
2007 Kettunen P, Spencer-Dene B, Furmanek T, Kvinnsland IH, Dickson C, Thesleff I, Luukko K. Fgfr2b mediated epithelial-mesenchymal interactions coordinate tooth morphogenesis and dental trigeminal axon patterning. Mechanisms of Development. 124: 868-83. PMID 17951031 DOI: 10.1016/J.Mod.2007.09.003  1
2007 Thesleff I, Järvinen E, Suomalainen M. Affecting tooth morphology and renewal by fine-tuning the signals mediating cell and tissue interactions. Novartis Foundation Symposium. 284: 142-53; discussion 1. PMID 17710852 DOI: 10.1002/9780470319390.Ch10  1
2007 Thesleff I, Wang XP, Suomalainen M. Regulation of epithelial stem cells in tooth regeneration. Comptes Rendus Biologies. 330: 561-4. PMID 17631454 DOI: 10.1016/J.Crvi.2007.03.005  1
2007 Wang XP, Suomalainen M, Felszeghy S, Zelarayan LC, Alonso MT, Plikus MV, Maas RL, Chuong CM, Schimmang T, Thesleff I. An integrated gene regulatory network controls stem cell proliferation in teeth. Plos Biology. 5: e159. PMID 17564495 DOI: 10.1371/Journal.Pbio.0050159  1
2007 Yamashiro T, Zheng L, Shitaku Y, Saito M, Tsubakimoto T, Takada K, Takano-Yamamoto T, Thesleff I. Wnt10a regulates dentin sialophosphoprotein mRNA expression and possibly links odontoblast differentiation and tooth morphogenesis. Differentiation; Research in Biological Diversity. 75: 452-62. PMID 17286598 DOI: 10.1111/J.1432-0436.2006.00150.X  1
2007 Pummila M, Fliniaux I, Jaatinen R, James MJ, Laurikkala J, Schneider P, Thesleff I, Mikkola ML. Ectodysplasin has a dual role in ectodermal organogenesis: inhibition of Bmp activity and induction of Shh expression. Development (Cambridge, England). 134: 117-25. PMID 17164417 DOI: 10.1242/Dev.02708  1
2007 Lieberman D, Thesleff I, Oxnard C, Hallgrimsson B, Duboule D, Jernvall J, Weiss K, Cheverud J, Donoghue P, Raff R, Coates M, Hall BK. Discussion Novartis Foundation Symposium. 284: 153-157.  1
2007 Bard J, Bell MA, Brakefield PM, Budd G, Coates M, Duboule D, Hall BK, Hallgrimsson B, Jernvall J, Lieberman D, Raff R, Stern D, Wagner G, Weiss K. Discussion Novartis Foundation Symposium. 284: 101-109.  1
2007 Bard J, Bell MA, Brakefield PM, Budd G, Coates M, Duboule D, Hall BK, Hallgrimsson B, Jernvall J, Lieberman D, Raff R, Stern D, Wagner G, Weiss K. Discussion Novartis Foundation Symposium. 284: 101-109.  1
2007 Bard J, Bell MA, Brakefield PM, Budd G, Coates M, Duboule D, Hall BK, Hallgrimsson B, Jernvall J, Lieberman D, Raff R, Stern D, Wagner G, Weiss K. Discussion Novartis Foundation Symposium. 284: 101-109.  1
2007 Felszeghy S, Suomalainen M, Thesleff I. Modulation of BMP activity affects size and shape of incisor morphogenesis European Cells and Materials. 14: 84.  1
2007 Tummers M, Yamashiro T, Thesleff I. The flexible modulation of epithelial differentiation in the cervical loop sheds new light on the relationship between root formation and continuous growth European Cells and Materials. 14: 48.  1
2007 Suomalainen M, Wang XP, Felszeghy S, Zelarayan LC, Alonso MT, Plikus MV, Maas RL, Chuong CM, Schimmang T, Thesleff I. Balance between BMP4 and activin signalling regulates Fgf3 expression and epithelial stem cells in mouse incisors European Cells and Materials. 14: 132.  1
2007 Wang XP, Suomalainen M, Thesleff I. Regulation of the continuous growth of the mouse incisor by epithelial-mesenchymal interactions European Cells and Materials. 14: 21.  1
2007 Munne P, Thesleff I, Jernvall J. Molecular regulation of incisor fate in developing dentition European Cells and Materials. 14: 28.  1
2006 Järvinen E, Salazar-Ciudad I, Birchmeier W, Taketo MM, Jernvall J, Thesleff I. Continuous tooth generation in mouse is induced by activated epithelial Wnt/β-catenin signaling Proceedings of the National Academy of Sciences of the United States of America. 103: 18627-18632. PMID 17121988 DOI: 10.1073/Pnas.0607289103  1
2006 Thesleff I. The genetic basis of tooth development and dental defects. American Journal of Medical Genetics. Part A. 140: 2530-5. PMID 16838332 DOI: 10.1002/Ajmg.A.31360  1
2006 James MJ, Järvinen E, Wang XP, Thesleff I. Different roles of Runx2 during early neural crest-derived bone and tooth development. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 21: 1034-44. PMID 16813524 DOI: 10.1359/Jbmr.060413  1
2006 Laurikkala J, Mikkola ML, James M, Tummers M, Mills AA, Thesleff I. p63 regulates multiple signalling pathways required for ectodermal organogenesis and differentiation. Development (Cambridge, England). 133: 1553-63. PMID 16524929 DOI: 10.1242/Dev.02325  1
2005 Kassai Y, Munne P, Hotta Y, Penttilä E, Kavanagh K, Ohbayashi N, Takada S, Thesleff I, Jernvall J, Itoh N. Regulation of mammalian tooth cusp patterning by ectodin. Science (New York, N.Y.). 309: 2067-70. PMID 16179481 DOI: 10.1126/Science.1116848  1
2005 Løvschall H, Tummers M, Thesleff I, Füchtbauer EM, Poulsen K. Activation of the Notch signaling pathway in response to pulp capping of rat molars. European Journal of Oral Sciences. 113: 312-7. PMID 16048523 DOI: 10.1111/J.1600-0722.2005.00221.X  1
2005 Rice R, Thesleff I, Rice DP. Regulation of Twist, Snail, and Id1 is conserved between the developing murine palate and tooth. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 234: 28-35. PMID 16028273 DOI: 10.1002/Dvdy.20501  1
2005 Rice R, Rice DP, Thesleff I. Foxc1 integrates Fgf and Bmp signalling independently of twist or noggin during calvarial bone development. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 233: 847-52. PMID 15906377 DOI: 10.1002/Dvdy.20430  1
2005 Aberg T, Rice R, Rice D, Thesleff I, Waltimo-Sirén J. Chondrogenic potential of mouse calvarial mesenchyme. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 53: 653-63. PMID 15872058 DOI: 10.1369/Jhc.4A6518.2005  1
2005 Wang XP, Aberg T, James MJ, Levanon D, Groner Y, Thesleff I. Runx2 (Cbfa1) inhibits Shh signaling in the lower but not upper molars of mouse embryos and prevents the budding of putative successional teeth. Journal of Dental Research. 84: 138-43. PMID 15668330 DOI: 10.1177/154405910508400206  1
2004 Kangas AT, Evans AR, Thesleff I, Jernvall J. Nonindependence of mammalian dental characters Nature. 432: 211-214. PMID 15538367 DOI: 10.1038/Nature02927  1
2004 Wang XP, Suomalainen M, Jorgez CJ, Matzuk MM, Werner S, Thesleff I. Follistatin regulates enamel patterning in mouse incisors by asymmetrically inhibiting BMP signaling and ameloblast differentiation. Developmental Cell. 7: 719-30. PMID 15525533 DOI: 10.1016/J.Devcel.2004.09.012  1
2004 Mustonen T, Ilmonen M, Pummila M, Kangas AT, Laurikkala J, Jaatinen R, Pispa J, Gaide O, Schneider P, Thesleff I, Mikkola ML. Ectodysplasin A1 promotes placodal cell fate during early morphogenesis of ectodermal appendages. Development (Cambridge, England). 131: 4907-19. PMID 15371307 DOI: 10.1242/Dev.01377  1
2004 Pispa J, Mustonen T, Mikkola ML, Kangas AT, Koppinen P, Lukinmaa PL, Jernvall J, Thesleff I. Tooth patterning and enamel formation can be manipulated by misexpression of TNF receptor Edar Developmental Dynamics. 231: 432-440. PMID 15366021 DOI: 10.1002/Dvdy.20138  1
2004 Yamashiro T, Wang XP, Li Z, Oya S, Aberg T, Fukunaga T, Kamioka H, Speck NA, Takano-Yamamoto T, Thesleff I. Possible roles of Runx1 and Sox9 in incipient intramembranous ossification. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 19: 1671-7. PMID 15355562 DOI: 10.1359/Jbmr.040801  1
2004 Wang XP, Suomalainen M, Jorgez CJ, Matzuk MM, Wankell M, Werner S, Thesleff I. Modulation of activin/bone morphogenetic protein signaling by follistatin is required for the morphogenesis of mouse molar teeth. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 231: 98-108. PMID 15305290 DOI: 10.1002/Dvdy.20118  1
2004 James MJ, Järvinen E, Thesleff I. Bono1: a gene associated with regions of deposition of bone and dentine. Gene Expression Patterns : Gep. 4: 595-9. PMID 15261838 DOI: 10.1016/J.Modgep.2004.01.013  1
2004 Rice R, Spencer-Dene B, Connor EC, Gritli-Linde A, McMahon AP, Dickson C, Thesleff I, Rice DP. Disruption of Fgf10/Fgfr2b-coordinated epithelial-mesenchymal interactions causes cleft palate. The Journal of Clinical Investigation. 113: 1692-700. PMID 15199404 DOI: 10.1172/Jci20384  1
2004 Huysseune A, Thesleff I. Continuous tooth replacement: the possible involvement of epithelial stem cells. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 26: 665-71. PMID 15170864 DOI: 10.1002/Bies.20039  1
2004 Aberg T, Wang XP, Kim JH, Yamashiro T, Bei M, Rice R, Ryoo HM, Thesleff I. Runx2 mediates FGF signaling from epithelium to mesenchyme during tooth morphogenesis. Developmental Biology. 270: 76-93. PMID 15136142 DOI: 10.1016/J.Ydbio.2004.02.012  1
2004 Lammi L, Arte S, Somer M, Jarvinen H, Lahermo P, Thesleff I, Pirinen S, Nieminen P. Mutations in AXIN2 cause familial tooth agenesis and predispose to colorectal cancer. American Journal of Human Genetics. 74: 1043-50. PMID 15042511 DOI: 10.1086/386293  1
2004 Felszeghy S, Módis L, Németh P, Nagy G, Zelles T, Agre P, Laurikkala J, Fejerskov O, Thesleff I, Nielsen S. Expression of aquaporin isoforms during human and mouse tooth development. Archives of Oral Biology. 49: 247-57. PMID 15003543 DOI: 10.1016/J.Archoralbio.2003.09.011  1
2004 Partanen AM, Kiukkonen A, Sahlberg C, Alaluusua S, Thesleff I, Pohjanvirta R, Lukinmaa PL. Developmental toxicity of dioxin to mouse embryonic teeth in vitro: arrest of tooth morphogenesis involves stimulation of apoptotic program in the dental epithelium. Toxicology and Applied Pharmacology. 194: 24-33. PMID 14728976 DOI: 10.1016/J.Taap.2003.08.014  1
2004 Aberg T, Cavender A, Gaikwad JS, Bronckers AL, Wang X, Waltimo-Sirén J, Thesleff I, D'Souza RN. Phenotypic changes in dentition of Runx2 homozygote-null mutant mice. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 52: 131-9. PMID 14688224 DOI: 10.1177/002215540405200113  1
2004 Tummers M, Thesleff I. Epithelial Stem Cell Niche in the Tooth Handbook of Stem Cells. 1: 265-271. DOI: 10.1016/B978-012436643-5/50032-8  1
2003 Nieminen P, Kotilainen J, Aalto Y, Knuutila S, Pirinen S, Thesleff I. MSX1 gene is deleted in Wolf-Hirschhorn syndrome patients with oligodontia. Journal of Dental Research. 82: 1013-7. PMID 14630905 DOI: 10.1177/154405910308201215  1
2003 Laurikkala J, Kassai Y, Pakkasjärvi L, Thesleff I, Itoh N. Identification of a secreted BMP antagonist, ectodin, integrating BMP, FGF, and SHH signals from the tooth enamel knot. Developmental Biology. 264: 91-105. PMID 14623234 DOI: 10.1016/J.Ydbio.2003.08.011  1
2003 Thesleff I. Developmental biology and building a tooth. Quintessence International (Berlin, Germany : 1985). 34: 613-20. PMID 14620213  1
2003 Lammi L, Halonen K, Pirinen S, Thesleff I, Arte S, Nieminen P. A missense mutation in PAX9 in a family with distinct phenotype of oligodontia. European Journal of Human Genetics : Ejhg. 11: 866-71. PMID 14571272 DOI: 10.1038/Sj.Ejhg.5201060  1
2003 Pispa J, Thesleff I. Mechanisms of ectodermal organogenesis. Developmental Biology. 262: 195-205. PMID 14550785 DOI: 10.1016/S0012-1606(03)00325-7  1
2003 Rice R, Rice DP, Olsen BR, Thesleff I. Progression of calvarial bone development requires Foxc1 regulation of Msx2 and Alx4. Developmental Biology. 262: 75-87. PMID 14512019 DOI: 10.1016/S0012-1606(03)00355-5  1
2003 Pispa J, Mikkola ML, Mustonen T, Thesleff I. Ectodysplasin, Edar and TNFRSF19 are expressed in complementary and overlapping patterns during mouse embryogenesis. Gene Expression Patterns : Gep. 3: 675-9. PMID 12972005 DOI: 10.1016/S1567-133X(03)00092-9  1
2003 Rice DP, Rice R, Thesleff I. Fgfr mRNA isoforms in craniofacial bone development. Bone. 33: 14-27. PMID 12919696 DOI: 10.1016/S8756-3282(03)00163-7  1
2003 Mustonen T, Pispa J, Mikkola ML, Pummila M, Kangas AT, Pakkasjärvi L, Jaatinen R, Thesleff I. Stimulation of ectodermal organ development by Ectodysplasin-A1. Developmental Biology. 259: 123-36. PMID 12812793 DOI: 10.1016/S0012-1606(03)00157-X  1
2003 Mikkola ML, Thesleff I. Ectodysplasin signaling in development. Cytokine & Growth Factor Reviews. 14: 211-24. PMID 12787560 DOI: 10.1016/S1359-6101(03)00020-0  1
2003 Rice DP, Rice R, Thesleff I. Molecular mechanisms in calvarial bone and suture development, and their relation to craniosynostosis. European Journal of Orthodontics. 25: 139-48. PMID 12737212 DOI: 10.1093/Ejo/25.2.139  1
2003 Thesleff I, Tummers M. Stem cells and tissue engineering: prospects for regenerating tissues in dental practice. Medical Principles and Practice : International Journal of the Kuwait University, Health Science Centre. 12: 43-50. PMID 12707500 DOI: 10.1159/000069840  1
2003 Kusu N, Laurikkala J, Imanishi M, Usui H, Konishi M, Miyake A, Thesleff I, Itoh N. Sclerostin is a novel secreted osteoclast-derived bone morphogenetic protein antagonist with unique ligand specificity. The Journal of Biological Chemistry. 278: 24113-7. PMID 12702725 DOI: 10.1074/Jbc.M301716200  1
2003 Thesleff I. Epithelial-mesenchymal signalling regulating tooth morphogenesis. Journal of Cell Science. 116: 1647-8. PMID 12665545 DOI: 10.1242/Jcs.00410  1
2003 Yamashiro T, Tummers M, Thesleff I. Expression of bone morphogenetic proteins and Msx genes during root formation. Journal of Dental Research. 82: 172-6. PMID 12598544 DOI: 10.1177/154405910308200305  1
2003 Tummers M, Thesleff I. Root or crown: a developmental choice orchestrated by the differential regulation of the epithelial stem cell niche in the tooth of two rodent species. Development (Cambridge, England). 130: 1049-57. PMID 12571097 DOI: 10.1242/Dev.00332  1
2002 Yamashiro T, Aberg T, Levanon D, Groner Y, Thesleff I. Expression of Runx1, -2 and -3 during tooth, palate and craniofacial bone development. Mechanisms of Development. 119: S107-10. PMID 14516670 DOI: 10.1016/S0925-4773(03)00101-1  1
2002 Yamashiro T, Aberg T, Levanon D, Groner Y, Thesleff I. Expression of Runx1, -2 and -3 during tooth, palate and craniofacial bone development. Gene Expression Patterns : Gep. 2: 109-12. PMID 12617847 DOI: 10.1016/S0925-4773(02)00298-8  1
2002 Mustonen T, Tümmers M, Mikami T, Itoh N, Zhang N, Gridley T, Thesleff I. Lunatic fringe, FGF, and BMP regulate the Notch pathway during epithelial morphogenesis of teeth. Developmental Biology. 248: 281-93. PMID 12167404 DOI: 10.1006/Dbio.2002.0734  1
2002 Thesleff I, Mikkola M. The role of growth factors in tooth development. International Review of Cytology. 217: 93-135. PMID 12019566 DOI: 10.1016/S0074-7696(02)17013-6  1
2002 Thesleff I, Mikkola ML. Death receptor signaling giving life to ectodermal organs. Science's Stke : Signal Transduction Knowledge Environment. 2002: pe22. PMID 11997580 DOI: 10.1126/Stke.2002.131.Pe22  1
2002 Sahlberg C, Mustonen T, Thesleff I. Explant cultures of embryonic epithelium. Analysis of mesenchymal signals. Methods in Molecular Biology (Clifton, N.J.). 188: 373-82. PMID 11987559 DOI: 10.1385/1-59259-185-X:373  1
2002 Laurikkala J, Pispa J, Jung HS, Nieminen P, Mikkola M, Wang X, Saarialho-Kere U, Galceran J, Grosschedl R, Thesleff I. Regulation of hair follicle development by the TNF signal ectodysplasin and its receptor Edar. Development (Cambridge, England). 129: 2541-53. PMID 11973284  1
2002 Vartiainen MK, Mustonen T, Mattila PK, Ojala PJ, Thesleff I, Partanen J, Lappalainen P. The three mouse actin-depolymerizing factor/cofilins evolved to fulfill cell-type-specific requirements for actin dynamics. Molecular Biology of the Cell. 13: 183-94. PMID 11809832 DOI: 10.1091/Mbc.01-07-0331  1
2001 Thesleff I, Keränen S, Jernvall J. Enamel knots as signaling centers linking tooth morphogenesis and odontoblast differentiation. Advances in Dental Research. 15: 14-18. PMID 2003051454  1
2001 Thesleff I, Keränen S, Jernvall J. Enamel knots as signaling centers linking tooth morphogenesis and odontoblast differentiation. Advances in Dental Research. 15: 14-8. PMID 12640732 DOI: 10.1177/08959374010150010401  1
2001 Thesleff I. [Cranial and facial anomalies]. Duodecim; LääKetieteellinen Aikakauskirja. 117: 1707-13. PMID 12181933  1
2001 Nieminen P, Arte S, Tanner D, Paulin L, Alaluusua S, Thesleff I, Pirinen S. Identification of a nonsense mutation in the PAX9 gene in molar oligodontia. European Journal of Human Genetics : Ejhg. 9: 743-6. PMID 11781684 DOI: 10.1038/Sj.Ejhg.5200715  1
2001 Koppinen P, Pispa J, Laurikkala J, Thesleff I, Mikkola ML. Signaling and subcellular localization of the TNF receptor Edar. Experimental Cell Research. 269: 180-92. PMID 11570810 DOI: 10.1006/Excr.2001.5331  1
2001 Pirinen S, Kentala A, Nieminen P, Varilo T, Thesleff I, Arte S. Recessively inherited lower incisor hypodontia. Journal of Medical Genetics. 38: 551-6. PMID 11494968 DOI: 10.1136/Jmg.38.8.551  1
2001 Arte S, Nieminen P, Apajalahti S, Haavikko K, Thesleff I, Pirinen S. Characteristics of incisor-premolar hypodontia in families. Journal of Dental Research. 80: 1445-50. PMID 11437217 DOI: 10.1177/00220345010800051201  1
2001 Sahlberg C, Aukhil I, Thesleff I. Tenascin-C in developing mouse teeth: expression of splice variants and stimulation by TGFbeta and FGF. European Journal of Oral Sciences. 109: 114-24. PMID 11347655 DOI: 10.1034/J.1600-0722.2001.00990.X  1
2001 Laurikkala J, Mikkola M, Mustonen T, Aberg T, Koppinen P, Pispa J, Nieminen P, Galceran J, Grosschedl R, Thesleff I. TNF signaling via the ligand-receptor pair ectodysplasin and edar controls the function of epithelial signaling centers and is regulated by Wnt and activin during tooth organogenesis. Developmental Biology. 229: 443-55. PMID 11203701 DOI: 10.1006/Dbio.2000.9955  1
2000 Sariola H, Thesleff I, Makarow M. [Mice, yeasts and flies--what do genes of the model organisms tell about life and its evolution]. Duodecim; LääKetieteellinen Aikakauskirja. 116: 1734-41. PMID 12001451  1
2000 Thesleff I. Genetic basis of tooth development and dental defects. Acta Odontologica Scandinavica. 58: 191-4. PMID 11144868 DOI: 10.1080/000163500750051728  1
2000 Jernvall J, Keränen SVE, Thesleff I. Evolutionary modification of development in mammalian teeth: Quantifying gene expression patterns and topography Proceedings of the National Academy of Sciences of the United States of America. 97: 14444-14448. PMID 11121045 DOI: 10.1073/Pnas.97.26.14444  1
2000 Kettunen P, Laurikkala J, Itäranta P, Vainio S, Itoh N, Thesleff I. Associations of FGF-3 and FGF-10 with signaling networks regulating tooth morphogenesis Developmental Dynamics. 219: 322-332. PMID 11066089 DOI: 10.1002/1097-0177(2000)9999:9999<::Aid-Dvdy1062>3.0.Co;2-J  1
2000 Pirvola U, Spencer-Dene B, Xing-Qun L, Kettunen P, Thesleff I, Fritzsch B, Dickson C, Ylikoski J. FGF/FGFR-2(IIIb) signaling is essential for inner ear morphogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 6125-34. PMID 10934262 DOI: 10.1523/Jneurosci.20-16-06125.2000  1
2000 Rice DPC, Åberg T, Chan YS, Tang Z, Kettunen PJ, Pakarinen L, Maxson RE, Thesleff I. Integration of FGF and TWIST in calvarial bone and suture development Development. 127: 1845-1855. PMID 10751173  1
2000 Jernvall J, Thesleff I. Reiterative signaling and patterning during mammalian tooth morphogenesis Mechanisms of Development. 92: 19-29. PMID 10704885 DOI: 10.1016/S0925-4773(99)00322-6  1
1999 Pispa J, Jung HS, Jernvall J, Kettunen P, Mustonen T, Tabata MJ, Kere J, Thesleff I. Cusp patterning defect in Tabby mouse teeth and its partial rescue by FGF Developmental Biology. 216: 521-534. PMID 10642790 DOI: 10.1006/Dbio.1999.9514  1
1999 Mikkola ML, Pispa J, Pekkanen M, Paulin L, Nieminen P, Kere J, Thesleff I. Ectodysplasin, a protein required for epithelial morphogenesis, is a novel TNF homologue and promotes cell-matrix adhesion Mechanisms of Development. 88: 133-146. PMID 10534613 DOI: 10.1016/S0925-4773(99)00180-X  1
1999 Harada H, Kettunen P, Jung HS, Mustonen T, Wang YA, Thesleff I. Localization of putative stem cells in dental epithelium and their association with Notch and FGF signaling Journal of Cell Biology. 147: 105-120. PMID 10508859 DOI: 10.1083/Jcb.147.1.105  1
1999 Ohshima H, Wartiovaara J, Thesleff I. Developmental regulation and ultrastructure of glycogen deposits during murine tooth morphogenesis Cell and Tissue Research. 297: 271-281. PMID 10470497 DOI: 10.1007/S004410051355  1
1999 Rice DPC, Kim HJ, Thesleff I. Apoptosis in murine calvarial bone and suture development European Journal of Oral Sciences. 107: 265-275. PMID 10467942 DOI: 10.1046/J.0909-8836.1999.Eos107406.X  1
1999 Thesleff I, Åberg T. Molecular regulation of tooth development Bone. 25: 123-125. PMID 10423036 DOI: 10.1016/S8756-3282(99)00119-2  1
1999 Keränen SVE, Kettunen P, Åberg T, Thesleff I, Jernvall J. Gene expression patterns associated with suppression of odontogenesis in mouse and vole diastema regions Development Genes and Evolution. 209: 495-506. PMID 10415326 DOI: 10.1007/S004270050282  1
1999 D'Souza RN, Åberg T, Gaikwad J, Cavender A, Owen M, Karsenty G, Thesleff I. Cbfa1 is required for epithelial-mesenchymal interactions regulating tooth development in mice Development. 126: 2911-2920. PMID 10357935  1
1999 Jung HS, Oropeza V, Thesleff I. Shh, Bmp-2, Bmp-4 and Fgf-8 are associated with initiation and patterning of mouse tongue papillae Mechanisms of Development. 81: 179-182. PMID 10330496 DOI: 10.1016/S0925-4773(98)00234-2  1
1999 Sahlberg C, Reponen P, Tryggvason K, Thesleff I. Timp-1, -2 and -3 show coexpression with gelatinases A and B during mouse tooth morphogenesis European Journal of Oral Sciences. 107: 121-130. PMID 10232461 DOI: 10.1046/J.0909-8836.1999.Eos107208.X  1
1998 Thesleff I. The genetic basis of normal and abnormal craniofacial development Acta Odontologica Scandinavica. 56: 321-325. PMID 10066109 DOI: 10.1080/000163598428248  1
1998 Partanen AM, Alaluusua S, Miettinen PJ, Thesleff I, Tuomisto J, Pohjanvirta R, Lukinmaa PL. Epidermal growth factor receptor as a mediator of developmental toxicity of dioxin in mouse embryonic teeth Laboratory Investigation. 78: 1473-1481. PMID 9881947  1
1998 Keränen SVE, Åberg T, Kettunen P, Thesleff I, Jernvall J. Association of developmental regulatory genes with the development of different molar tooth shapes in two species of rodents Development Genes and Evolution. 208: 477-486. PMID 9799429 DOI: 10.1007/S004270050206  1
1998 Luukko K, Saarma M, Thesleff I. Neurturin mRNA expression suggests roles in trigeminal innervation of the first branchial arch and in tooth formation Developmental Dynamics. 213: 207-219. PMID 9786421 DOI: 10.1002/(Sici)1097-0177(199810)213:2<207::Aid-Aja6>3.0.Co;2-K  1
1998 Montonen O, Ezer S, Laurikkala J, Karjalainen-Lindsberg ML, Thesleff I, Kere J, Saarialho-Kere U. Expression of the anhidrotic ectodermal dysplasia gene is reduced in skin cancer coinciding with reduced E-cadherin Experimental Dermatology. 7: 168-174. PMID 9758413 DOI: 10.1111/J.1600-0625.1998.Tb00319.X  1
1998 Bayés M, Hartung AJ, Ezer S, Pispa J, Thesleff I, Srivastava AK, Kere J. The anhidrotic ectodermal dysplasia gene (EDA) undergoes alternative splicing and encodes ectodysplasin-A with deletion mutations in collagenous repeats Human Molecular Genetics. 7: 1661-1669. PMID 9736768 DOI: 10.1093/Hmg/7.11.1661  1
1998 Sahlberg C, Hormia M, Airenne T, Thesleff I. Laminin γ2 expression is developmentally regulated during murine tooth morphogenesis and is intense in ameloblasts Journal of Dental Research. 77: 1589-1596. PMID 9719032  1
1998 Kettunen P, Karavanova I, Thesleff I. Responsiveness of developing dental tissues to fibroblast growth factors: Expression of splicing alternatives of FGFR1, -2, -3, and of FGFR4; and stimulation of cell proliferation by FGF-2, -4, -8, and -9 Developmental Genetics. 22: 374-385. PMID 9664689 DOI: 10.1002/(Sici)1520-6408(1998)22:4<374::Aid-Dvg7>3.0.Co;2-3  1
1998 Hormia M, Sahlberg C, Thesleff I, Airenne T. The epithelium-tooth interface - A basal lamina rich in laminin-5 and lacking other known laminin isoforms Journal of Dental Research. 77: 1479-1485. PMID 9663432 DOI: 10.1177/00220345980770070201  1
1998 Nieminen P, Pekkanen M, Åberg T, Thesleff I. A graphical WWW-database on gene expression in tooth European Journal of Oral Sciences. 106: 7-11. PMID 9541196 DOI: 10.1111/J.1600-0722.1998.Tb02146.X  1
1998 Kettunen P, Thesleff I. Expression and function of FGFs-4, -8, and -9 suggest functional redundancy and repetitive use as epithelial signals during tooth morphogenesis Developmental Dynamics. 211: 256-268. PMID 9520113 DOI: 10.1002/(Sici)1097-0177(199803)211:3<256::Aid-Aja7>3.0.Co;2-G  1
1998 Montonen O, Ezer S, Saarialho-Kere UK, Herva R, Karjalainen-Lindsberg ML, Kaitila I, Schlessinger D, Srivastava AK, Thesleff I, Kere J. The gene defective in anhidrotic ectodermal dysplasia is expressed in the developing epithelium, neuroectoderm, thymus, and bone. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 46: 281-9. PMID 9487109 DOI: 10.1177/002215549804600301  1
1998 Jernvall J, Åberg T, Kettunen P, Keränen S, Thesleff I. The life history of an embryonic signaling center: BMP-4 induces p21 and is associated with apoptosis in the mouse tooth enamel knot Development. 125: 161-169. PMID 9486790  1
1998 Kim HJ, Rice DPC, Kettunen PJ, Thesleff I. FGF-, BMP- and Shh-mediated signalling pathways in the regulation of cranial suture morphogenesis and calvarial bone development Development. 125: 1241-1251. PMID 9477322  1
1997 Sariola H, Thesleff I. "There is always space for some new molecules!" | "Kyllä molekyylejä maailmaan mahtuu!" Duodecim. 113: 1393-1400. PMID 10622148  1
1997 Thesleff I, Jernvall J. The enamel knot: A putative signaling center regulating tooth development Cold Spring Harbor Symposia On Quantitative Biology. 62: 257-267. PMID 9598359 DOI: 10.1101/Sqb.1997.062.01.032  1
1997 Rice DPC, Kim HJ, Thesleff I. Detection of gelatinase B expression reveals osteoclastic bone resorption as a feature of early calvarial bone development Bone. 21: 479-486. PMID 9430236 DOI: 10.1016/S8756-3282(97)00182-8  1
1997 Luukko K, Suvanto P, Saarma M, Thesleff I. Expression of GDNF and its receptors in developing tooth is developmentally regulated and suggests multiple roles in innervation and organogenesis Developmental Dynamics. 210: 463-471. PMID 9415430 DOI: 10.1002/(Sici)1097-0177(199712)210:4<463::Aid-Aja9>3.0.Co;2-E  1
1997 Åberg T, Wozney J, Thesleff I. Expression patterns of bone morphogenetic proteins (Bmps) in the developing mouse tooth suggest roles in morphogenesis and cell differentiation Developmental Dynamics. 210: 383-396. PMID 9415424 DOI: 10.1002/(Sici)1097-0177(199712)210:4<383::Aid-Aja3>3.0.Co;2-C  1
1997 Thesleff I, Sharpe P. Signalling networks regulating dental development Mechanisms of Development. 67: 111-123. PMID 9392510 DOI: 10.1016/S0925-4773(97)00115-9  1
1997 Srivastava AK, Pispa J, Hartung AJ, Du Y, Ezer S, Jenks T, Shimada T, Pekkanen M, Mikkola ML, Ko MS, Thesleff I, Kere J, Schlessinger D. The Tabby phenotype is caused by mutation in a mouse homologue of the EDA gene that reveals novel mouse and human exons and encodes a protein (ectodysplasin-A) with collagenous domains. Proceedings of the National Academy of Sciences of the United States of America. 94: 13069-74. PMID 9371801 DOI: 10.1073/Pnas.94.24.13069  1
1997 Iivanainen A, Kortesmaa J, Sahlberg C, Morita T, Bergmann U, Thesleff I, Tryggvason K. Primary structure, developmental expression, and immunolocalization of the murine laminin alpha4 chain. The Journal of Biological Chemistry. 272: 27862-8. PMID 9346933 DOI: 10.1074/Jbc.272.44.27862  1
1997 Luukko K, Arumäe U, Karavanov A, Moshnyakov M, Sainio K, Sariola H, Saarma M, Thesleff I. Neurotrophin mRNA expression in the developing tooth suggests multiple roles in innervation and organogenesis Developmental Dynamics. 210: 117-129. PMID 9337133 DOI: 10.1002/(Sici)1097-0177(199710)210:2<117::Aid-Aja5>3.0.Co;2-J  1
1997 Thesleff I, Åberg T. Tooth morphogenesis and the differentiation of ameloblasts Ciba Foundation Symposia. 3-17. PMID 9189614  1
1997 Mitsiadis TA, Henrique D, Thesleff I, Lendahl U. Mouse Serrate-1 (Jagged-1): expression in the developing tooth is regulated by epithelial-mesenchymal interactions and fibroblast growth factor-4. Development (Cambridge, England). 124: 1473-83. PMID 9108364  1
1996 Mitsiadis TA, Thesleff I, Lendahl U. Mouse Serrate-1 and Notch genes differ in their response to signaling molecules during odontogenesis The International Journal of Developmental Biology. 113S-114S. PMID 9087721 DOI: 10.1387/Ijdb.9087721  1
1996 Luukko K, Moshnyakov M, Sainio K, Saarma M, Sariola H, Thesleff I. Expression of neurotrophin receptors during rat tooth development is developmentally regulated, independent of innervation, and suggests functions in the regulation of morphogenesis and innervation Developmental Dynamics. 206: 87-99. PMID 9019249 DOI: 10.1002/(Sici)1097-0177(199605)206:1<87::Aid-Aja8>3.0.Co;2-X  1
1996 Thesleff I, Nieminen P. Tooth morphogenesis and cell differentiation Current Opinion in Cell Biology. 8: 844-850. PMID 8939666 DOI: 10.1016/S0955-0674(96)80086-X  1
1996 Arte S, Nieminen P, Pirinen S, Thesleff I, Peltonen L. Gene defect in hypodontia: Exclusion of EGF, EGFR, and FGF-3 as candidate genes Journal of Dental Research. 75: 1346-1352. PMID 8831628 DOI: 10.1177/00220345960750060401  1
1996 Vaahtokari A, Åberg T, Jernvall J, Keränen S, Thesleff I. The enamel knot as a signaling center in the developing mouse tooth Mechanisms of Development. 54: 39-43. PMID 8808404 DOI: 10.1016/0925-4773(95)00459-9  1
1996 Thesleff I, Vaahtokari A, Vainio S, Jowett A. Molecular mechanisms of cell and tissue interactions during early tooth development Anatomical Record. 245: 151-161. PMID 8769660 DOI: 10.1002/(Sici)1097-0185(199606)245:2<151::Aid-Ar4>3.0.Co;2-#  1
1996 Aukhil I, Sahlberg C, Thesleff I. Basal layer of epithelium expresses tenascin mRNA during healing of incisional skin wounds Journal of Periodontal Research. 31: 105-112. PMID 8708937 DOI: 10.1111/J.1600-0765.1996.Tb00471.X  1
1996 Thesleff I. Two genes for missing teeth Nature Genetics. 13: 379-380. PMID 8696323 DOI: 10.1038/Ng0896-379  1
1996 Vaahtokari A, Åberg T, Thesleff I. Apoptosis in the developing tooth: Association with an embryonic signaling center and suppression by EGF and FGF-4 Development. 122: 121-129. PMID 8565823  1
1996 Thesleff I, Sahlberg C. Growth factors as inductive signals regulating tooth morphogenesis Seminars in Cell and Developmental Biology. 7: 185-193. DOI: 10.1006/Scdb.1996.0025  1
1995 Lukinmaa PL, Jensen BL, Thesleff I, Andreason JO, Kreiborg S. Histological observations of teeth and peridental tissues in cleidocranial dysplasia imply increased activity of odontogenic epithelium and abnormal bone remodeling Journal of Craniofacial Genetics and Developmental Biology. 15: 212-221. PMID 8719350  1
1995 Davideau JL, Sahlberg C, Blin C, Papagerais P, Thesleff I, Berdal A. Differential expression of the full-length and secreted truncated forms of EGF receptor during formation of dental tissues International Journal of Developmental Biology. 39: 605-615. PMID 8619959 DOI: 10.1387/Ijdb.8619959  1
1995 Mitsiadis TA, Salmivirta M, Muramatsu T, Muramatsu H, Rauvala H, Lehtonen E, Jalkanen M, Thesleff I. Expression of the heparin-binding cytokines, midkine (MK) and HB-GAM (pleiotrophin) is associated with epithelial-mesenchymal interactions during fetal development and organogenesis Development. 121: 37-51. PMID 7867507  1
1995 Elomaa O, Kangas M, Sahlberg C, Tuukkanen J, Sormunen R, Liakka A, Thesleff I, Kraal G, Tryggvason K. Cloning of a novel bacteria-binding receptor structurally related to scavenger receptors and expressed in a subset of macrophages Cell. 80: 603-609. PMID 7867067 DOI: 10.1016/0092-8674(95)90514-6  1
1995 Mitsiadis TA, Muramatsu T, Muramatsu H, Thesleff I. Midkine (MK), a heparin-binding growth/differentiation factor, is regulated by retinoic acid and epithelial-mesenchymal interactions in the developing mouse tooth, and affects cell proliferation and morphogenesis Journal of Cell Biology. 129: 267-281. PMID 7698992 DOI: 10.1083/Jcb.129.1.267  1
1995 Nieminen P, Arte S, Pirinen S, Peltonen L, Thesleff I. Gene defect in hypodontia: exclusion of MSX1 and MSX2 as candidate genes Human Genetics. 96: 305-308. PMID 7649547 DOI: 10.1007/Bf00210412  1
1995 Reponen P, Leivo I, Sahlberg C, Apte SS, Olsen BR, Thesleff I, Tryggvason K. 92-kDa type IV collagenase and TIMP-3, but not 72-kDa type IV collagenase or TIMP-1 or TIMP-2, are highly expressed during mouse embryo implantation Developmental Dynamics. 202: 388-396. PMID 7626795 DOI: 10.1002/Aja.1002020408  1
1995 Thesleff I, Vaahtokari A, Partanen AM. Regulation of organogenesis. Common molecular mechanisms regulating the development of teeth and other organs International Journal of Developmental Biology. 39: 35-50. PMID 7626420 DOI: 10.1387/Ijdb.7626420  1
1995 Mitsiadis TA, Lardelli M, Lendahl U, Thesleff I. Expression of Notch 1, 2, and 3 is regulated by epithelial-mesenchymal interactions and retinoic acid in the developing mouse tooth and associated with determination of ameloblast cell fate Journal of Cell Biology. 130: 407-418. PMID 7615640 DOI: 10.1083/Jcb.130.2.407  1
1995 Tureckova J, Sahlberg C, Aberg T, Ruch JV, Thesleff I, Peterkova R. Comparison of expression of the msx-1, msx-2, BMP-2 and BMP-4 genes in the mouse upper diastemal and molar tooth primordia International Journal of Developmental Biology. 39: 459-468. PMID 7577436  1
1995 Thesleff I. Homeobox genes and growth factors in regulation of craniofacial and tooth morphogenesis Acta Odontologica Scandinavica. 53: 129-134. PMID 7572087 DOI: 10.3109/00016359509005962  1
1995 Thesleff I, Vaahtokari A, Kettunen P, Aberg T. Epithelial-mesenchymal signaling during tooth development Connective Tissue Research. 32: 9-15. PMID 7554939 DOI: 10.3109/03008209509013700  1
1995 Davideau JL, Sahlberg C, Thesleff I, Berdal A. EGF receptor expression in mineralized tissues: An in situ hybridization and immunocytochemical investigation in rat and human mandibles Connective Tissue Research. 32: 47-53. PMID 7554935 DOI: 10.3109/03008209509013705  1
1994 Reponen P, Sahlberg C, Munaut C, Thesleff I, Tryggvason K. High expression of 92-kD type IV collagenase (gelatinase B) in the osteoclast lineage during mouse development Journal of Cell Biology. 124: 1091-1102. PMID 8132709  1
1994 Reponen P, Sahlberg C, Munaut C, Thesleff I, Tryggvason K. High expression of 92-kDa type IV collagenase (gelatinase) in the osteoclast lineage during mouse development Annals of the New York Academy of Sciences. 732: 472-475. PMID 7978842 DOI: 10.1111/J.1749-6632.1994.Tb24789.X  1
1994 Jernvall J, Kettunen P, Karavanova I, Martin LB, Thesleff I. Evidence for the role of the enamel knot as a control center in mammalian tooth cusp formation: non-dividing cells express growth stimulating Fgf-4 gene. The International Journal of Developmental Biology. 38: 463-9. PMID 7848830 DOI: 10.1387/Ijdb.7848830  1
1993 Nieminen P, Vainio S, Jernvall J, Lukinmaa PL, Lehtonen E, Thesleff I. A chondroitin sulfate epitope in mammalian dental pulp and its developmental expression in mouse dental papilla. Journal of Dental Research. 72: 1460-1472. PMID 7693781 DOI: 10.1177/00220345930720110201  1
1992 Saxén L, Thesleff I. Epithelial-mesenchymal interactions in murine organogenesis. Ciba Foundation Symposium. 165: 183-93; discussion 1. PMID 1516468  0.24
1991 Lukinmaa PL, Mackie EJ, Thesleff I. Immunohistochemical Localization of the Matrix Glycoproteins-Tenascin and the ED-sequence-containing Form of Cellular Fibronectin—in Human Permanent Teeth and Periodontal Ligament Journal of Dental Research. 70: 19-26. PMID 1704020 DOI: 10.1177/00220345910700010201  1
1991 Sariola H, Saarma M, Sainio K, Arumäe U, Palgi J, Vaahtokari A, Thesleff I, Karavanov A. Dependence of kidney morphogenesis on the expression of nerve growth factor receptor. Science (New York, N.Y.). 254: 571-3. PMID 1658930 DOI: 10.1126/Science.1658930  1
1990 Vakeva L, Mackie E, Kantomaa T, Thesleff I. Comparison of the distribution patterns of tenascin and alkaline phosphatase in developing teeth, cartilage, and bone of rats and mice Anatomical Record. 228: 69-76. PMID 1700648 DOI: 10.1002/Ar.1092280111  1
1988 Thesleff I, Kantomaa T, Mackie E, Chiquet-Ehrismann R. Immunohistochemical localization of the matrix glycoprotein tenascin in the skull of the growing rat Archives of Oral Biology. 33: 383-390. PMID 2465754 DOI: 10.1016/0003-9969(88)90194-X  1
1987 Mackie EJ, Thesleff I, Chiquet-Ehrismann R. Tenascin is associated with chondrogenic and osteogenic differentiation in vivo and promotes chondrogenesis in vitro Journal of Cell Biology. 105: 2569-2579. PMID 2447094 DOI: 10.1083/Jcb.105.6.2569  1
1983 Ekblom P, Thesleff I, Saxén L, Miettinen A, Timpl R. Transferrin as a fetal growth factor: acquisition of responsiveness related to embryonic induction. Proceedings of the National Academy of Sciences of the United States of America. 80: 2651-5. PMID 6405384 DOI: 10.1073/Pnas.80.9.2651  1
1979 Hurmerinta K, Thesleff I, Saxén L. Inhibition of tooth germ differentiation in vitro by diazo-oxo-norleucine (DON). Journal of Embryology and Experimental Morphology. 50: 99-109. PMID 458364  1
1978 Thesleff I, Lehtonen E, Saxén L. Basement membrane formation in transfilter tooth culture and its relation to odontoblast differentiation. Differentiation; Research in Biological Diversity. 10: 71-9. PMID 640305 DOI: 10.1111/J.1432-0436.1978.Tb00948.X  1
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