Year |
Citation |
Score |
2016 |
Li XF, Cao RB, Luo J, Fan JM, Wang JM, Zhang YP, Gu JY, Feng XL, Zhou B, Chen PY. MicroRNA transcriptome profiling of mice brains infected with Japanese encephalitis virus by RNA sequencing. Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases. PMID 26845346 DOI: 10.1016/j.meegid.2016.01.028 |
0.331 |
|
2015 |
Liu YL, Cao R, Wang Y, Oldfield E. Farnesyl diphosphate synthase inhibitors with unique ligand-binding geometries. Acs Medicinal Chemistry Letters. 6: 349-54. PMID 25815158 DOI: 10.1021/Ml500528X |
0.571 |
|
2013 |
Zhu W, Zhang Y, Sinko W, Hensler ME, Olson J, Molohon KJ, Lindert S, Cao R, Li K, Wang K, Wang Y, Liu YL, Sankovsky A, de Oliveira CA, Mitchell DA, et al. Antibacterial drug leads targeting isoprenoid biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 110: 123-8. PMID 23248302 DOI: 10.1073/Pnas.1219899110 |
0.577 |
|
2012 |
Zhang Y, Fu-Yang Lin, Li K, Zhu W, Liu YL, Cao R, Pang R, Lee E, Axelson J, Hensler M, Wang K, Molohon KJ, Wang Y, Mitchell DA, Nizet V, et al. HIV-1 Integrase Inhibitor-Inspired Antibacterials Targeting Isoprenoid Biosynthesis. Acs Medicinal Chemistry Letters. 3: 402-406. PMID 22662288 DOI: 10.1021/Ml300038T |
0.547 |
|
2012 |
Lin FY, Liu YL, Li K, Cao R, Zhu W, Axelson J, Pang R, Oldfield E. Head-to-head prenyl tranferases: anti-infective drug targets. Journal of Medicinal Chemistry. 55: 4367-72. PMID 22486710 DOI: 10.1021/Jm300208P |
0.665 |
|
2011 |
Wang H, Sarikonda G, Puan KJ, Tanaka Y, Feng J, Giner JL, Cao R, Mönkkönen J, Oldfield E, Morita CT. Indirect stimulation of human Vγ2Vδ2 T cells through alterations in isoprenoid metabolism. Journal of Immunology (Baltimore, Md. : 1950). 187: 5099-113. PMID 22013129 DOI: 10.4049/Jimmunol.1002697 |
0.476 |
|
2011 |
Durrant JD, Cao R, Gorfe AA, Zhu W, Li J, Sankovsky A, Oldfield E, McCammon JA. Non-bisphosphonate inhibitors of isoprenoid biosynthesis identified via computer-aided drug design. Chemical Biology & Drug Design. 78: 323-32. PMID 21696546 DOI: 10.1111/J.1747-0285.2011.01164.X |
0.677 |
|
2011 |
Sinko W, de Oliveira C, Williams S, Van Wynsberghe A, Durrant JD, Cao R, Oldfield E, McCammon JA. Applying molecular dynamics simulations to identify rarely sampled ligand-bound conformational states of undecaprenyl pyrophosphate synthase, an antibacterial target. Chemical Biology & Drug Design. 77: 412-20. PMID 21294851 DOI: 10.1111/J.1747-0285.2011.01101.X |
0.522 |
|
2010 |
Lin FY, Liu CI, Liu YL, Zhang Y, Wang K, Jeng WY, Ko TP, Cao R, Wang AH, Oldfield E. Mechanism of action and inhibition of dehydrosqualene synthase. Proceedings of the National Academy of Sciences of the United States of America. 107: 21337-42. PMID 21098670 DOI: 10.1073/Pnas.1010907107 |
0.654 |
|
2010 |
Cao R, Zhang Y, Mann FM, Huang C, Mukkamala D, Hudock MP, Mead ME, Prisic S, Wang K, Lin FY, Chang TK, Peters RJ, Oldfield E. Diterpene cyclases and the nature of the isoprene fold. Proteins. 78: 2417-32. PMID 20602361 DOI: 10.1002/Prot.22751 |
0.749 |
|
2010 |
Zhang Y, Cao R, Yin F, Lin FY, Wang H, Krysiak K, No JH, Mukkamala D, Houlihan K, Li J, Morita CT, Oldfield E. Lipophilic pyridinium bisphosphonates: potent gammadelta T cell stimulators. Angewandte Chemie (International Ed. in English). 49: 1136-8. PMID 20039246 DOI: 10.1002/Anie.200905933 |
0.745 |
|
2009 |
Zhang Y, Cao R, Yin F, Hudock MP, Guo RT, Krysiak K, Mukherjee S, Gao YG, Robinson H, Song Y, No JH, Bergan K, Leon A, Cass L, Goddard A, et al. Lipophilic bisphosphonates as dual farnesyl/geranylgeranyl diphosphate synthase inhibitors: an X-ray and NMR investigation. Journal of the American Chemical Society. 131: 5153-62. PMID 19309137 DOI: 10.1021/Ja808285E |
0.75 |
|
2009 |
Song Y, Lin FY, Yin F, Hensler M, Rodrígues Poveda CA, Mukkamala D, Cao R, Wang H, Morita CT, González Pacanowska D, Nizet V, Oldfield E. Phosphonosulfonates are potent, selective inhibitors of dehydrosqualene synthase and staphyloxanthin biosynthesis in Staphylococcus aureus. Journal of Medicinal Chemistry. 52: 976-88. PMID 19191557 DOI: 10.1021/Jm801023U |
0.712 |
|
2009 |
Zhang Y, Cao R, Yin F, Lin F, Wang H, Krysiak K, No J, Mukkamala D, Houlihan K, Li J, Morita C, Oldfield E. Lipophilic Pyridinium Bisphosphonates: Potent γδ T Cell Stimulators Angewandte Chemie. 122: 1154-1156. DOI: 10.1002/ange.200905933 |
0.725 |
|
2008 |
K-M Chen C, Hudock MP, Zhang Y, Guo RT, Cao R, No JH, Liang PH, Ko TP, Chang TH, Chang SC, Song Y, Axelson J, Kumar A, Wang AH, Oldfield E. Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation. Journal of Medicinal Chemistry. 51: 5594-607. PMID 18800762 DOI: 10.1021/Jm800325Y |
0.771 |
|
2008 |
Cao R, Chen CK, Guo RT, Wang AH, Oldfield E. Structures of a potent phenylalkyl bisphosphonate inhibitor bound to farnesyl and geranylgeranyl diphosphate synthases. Proteins. 73: 431-9. PMID 18442135 DOI: 10.1002/Prot.22066 |
0.572 |
|
2007 |
Zhang Y, Hudock MP, Krysiak K, Cao R, Bergan K, Yin F, Leon A, Oldfield E. Activity of sulfonium bisphosphonates on tumor cell lines. Journal of Medicinal Chemistry. 50: 6067-79. PMID 17963374 DOI: 10.1021/Jm700991K |
0.754 |
|
2007 |
Guo RT, Cao R, Liang PH, Ko TP, Chang TH, Hudock MP, Jeng WY, Chen CK, Zhang Y, Song Y, Kuo CJ, Yin F, Oldfield E, Wang AH. Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases. Proceedings of the National Academy of Sciences of the United States of America. 104: 10022-7. PMID 17535895 DOI: 10.1073/Pnas.0702254104 |
0.77 |
|
2006 |
Mao J, Mukherjee S, Zhang Y, Cao R, Sanders JM, Song Y, Zhang Y, Meints GA, Gao YG, Mukkamala D, Hudock MP, Oldfield E. Solid-state NMR, crystallographic, and computational investigation of bisphosphonates and farnesyl diphosphate synthase-bisphosphonate complexes. Journal of the American Chemical Society. 128: 14485-97. PMID 17090032 DOI: 10.1021/Ja061737C |
0.748 |
|
2006 |
Yin F, Cao R, Goddard A, Zhang Y, Oldfield E. Enthalpy versus entropy-driven binding of bisphosphonates to farnesyl diphosphate synthase. Journal of the American Chemical Society. 128: 3524-5. PMID 16536518 DOI: 10.1021/Ja0601639 |
0.657 |
|
2006 |
Cao R, Hudock MP, Zhang Y, Wilson SR, Oldfield E. [1-Hydroxy-1-phosphono-2-(trimethylphosphonium-1-yl)ethyl]phosphonate monohydrate Acta Crystallographica Section E: Structure Reports Online. 62: o1055-o1057. DOI: 10.1107/S1600536806005010 |
0.763 |
|
2006 |
Zhang Y, Cao R, Hudock MP, Wilson SR, Oldfield E. [2-(Dimethylsulfonio)-1-hydroxy-1-phosphonoethyl]phosphonate monohydrate Acta Crystallographica Section E: Structure Reports Online. 62: o1006-o1008. DOI: 10.1107/S1600536806004405 |
0.756 |
|
2006 |
Cao R, Hudock MP, Zhang Y, Wilson SR, Oldfield E. [2-(3-Fluoropyridinium-1-yl)-1-hydroxy-1-phosphonoethyl]phosphonate Acta Crystallographica Section E: Structure Reports Online. 62: o1003-o1005. DOI: 10.1107/S1600536806004387 |
0.761 |
|
2006 |
Hudock MP, Cao R, Zhang Y, Wilson SR, Oldfield E. 1-hydroxy-1-phosphono-2-(trimethylarsonium-1-yl)ethanephosphonate monohydrate Acta Crystallographica Section E: Structure Reports Online. 62: o843-o845. DOI: 10.1107/S160053680600184X |
0.765 |
|
2004 |
Huang Z, Liu D, Madani N, Kumar S, Choi W, Cao R, Li Y, Gao Y, Dong C, Wang J, An J, Sodroski JG. A Novel Synthetic Chemokine Containing D-Amino Acids That Binds to the CXCR4 Receptor and Inhibits HIV-1 Infection. Blood. 104: 603-603. DOI: 10.1182/Blood.V104.11.603.603 |
0.304 |
|
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