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Douglas C. Beshore, Ph.D. - Publications

Affiliations: 
2007 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Natural product synthesis
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10 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Beshore DC, Haidle AM, Arasappan A, Lim YH, Raheem I, Roecker AJ, Shockley SE, Simov V. Building a Culture of Medicinal Chemistry Knowledge Sharing. Journal of Medicinal Chemistry. PMID 35192762 DOI: 10.1021/acs.jmedchem.1c02144  0.546
2016 Beshore DC, Johnson AW, DiPardo RM, Pitts DR, Cofre V, Kuduk SD. 2,5-Disubstituted Pyrazolo[4,3-c]cinnolin-3-ones Journal of Heterocyclic Chemistry. 54: 1558-1571. DOI: 10.1002/Jhet.2744  0.35
2010 Beshore DC, DiPardo RM, Kuduk SD. Preparation of 2,4,5-trisubstituted pyrazolo[4,3-c]quinolin-3-ones Tetrahedron Letters. 51: 970-973. DOI: 10.1016/J.Tetlet.2009.12.054  0.32
2009 Smith AB, Atasoylu O, Beshore DC. Construction of 5,6-Ring Fused 2-Pyridones: An Effective Annulation Tactic Achieved in Water. Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry. 2009: 2643-2646. PMID 20634903 DOI: 10.1055/S-0029-1217749  0.563
2008 Beshore DC, Smith AB. The lyconadins: enantioselective total syntheses of (+)-lyconadin A and (-)-lyconadin B. Journal of the American Chemical Society. 130: 13778-89. PMID 18798629 DOI: 10.1021/Ja804939R  0.314
2002 Bell IM, Gallicchio SN, Abrams M, Beese LS, Beshore DC, Bhimnathwala H, Bogusky MJ, Buser CA, Culberson JC, Davide J, Ellis-Hutchings M, Fernandes C, Gibbs JB, Graham SL, Hamilton KA, et al. 3-Aminopyrrolidinone farnesyltransferase inhibitors: design of macrocyclic compounds with improved pharmacokinetics and excellent cell potency. Journal of Medicinal Chemistry. 45: 2388-409. PMID 12036349 DOI: 10.1021/Jm010531D  0.308
2001 Bell IM, Gallicchio SN, Abrams M, Beshore DC, Buser CA, Culberson JC, Davide J, Ellis-Hutchings M, Fernandes C, Gibbs JB, Graham SL, Hartman GD, Heimbrook DC, Homnick CF, Huff JR, et al. Design and biological activity of (S)-4-(5-([1-(3-chlorobenzyl)-2-oxopyrrolidin-3-ylamino]methyl)imidazol-1-ylmethyl)benzonitrile, a 3-aminopyrrolidinone farnesyltransferase inhibitor with excellent cell potency. Journal of Medicinal Chemistry. 44: 2933-49. PMID 11520202 DOI: 10.1021/Jm010156P  0.306
2001 Beshore DC, Bell IM, Dinsmore CJ, Homnick CF, Culberson JC, Robinson RG, Fernandes C, Walsh ES, Abrams MT, Bhimnathwala HG, Davide JP, Ellis-Hutchings MS, Huber HA, Koblan KS, Buser CA, et al. Evaluation of amino acid-based linkers in potent macrocyclic inhibitors of farnesyl-protein transferase. Bioorganic & Medicinal Chemistry Letters. 11: 1817-21. PMID 11459639 DOI: 10.1016/S0960-894X(01)00340-7  0.323
2000 Bell IM, Beshore DC, Gallicchio SN, Williams TM. Efficient synthesis of 1-heterocyclic-3-aminopyrrolidinones Tetrahedron Letters. 41: 1141-1145. DOI: 10.1016/S0040-4039(99)02282-0  0.343
2000 Beshore DC, Dinsmore CJ. Efficient synthesis of unsymmetrical 1,4-disubstituted-2,3-diketopiperazines via tandem reductive amination-cyclization Tetrahedron Letters. 41: 8735-8739. DOI: 10.1016/S0040-4039(00)01565-3  0.343
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