Tatyana I. Igumenova, Ph.D. - Publications

Affiliations: 
2003 Columbia University, New York, NY 
Area:
NMR Structural Studies of Membrane Proteins, Enzymes, Hydrogen Bonding Geometry, and Dynamics

42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Katti SS, Igumenova TI. Protein-Cadmium Interactions in Crowded Biomolecular Environments Probed by In-cell and Lysate NMR Spectroscopy. Biorxiv : the Preprint Server For Biology. PMID 38405767 DOI: 10.1101/2023.11.03.565546  0.303
2022 Katti SS, Krieger IV, Ann J, Lee J, Sacchettini JC, Igumenova TI. Structural anatomy of Protein Kinase C C1 domain interactions with diacylglycerol and other agonists. Nature Communications. 13: 2695. PMID 35577811 DOI: 10.1038/s41467-022-30389-2  0.376
2021 Cole TR, Igumenova TI. Reactivity of Thiol-Rich Zn Sites in Diacylglycerol-Sensing PKC C1 Domain Probed by NMR Spectroscopy. Frontiers in Molecular Biosciences. 8: 728711. PMID 34447788 DOI: 10.3389/fmolb.2021.728711  0.324
2021 Katti S, Igumenova TI. Structural insights into C1-ligand interactions: Filling the gaps by in silico methods. Advances in Biological Regulation. 100784. PMID 33526356 DOI: 10.1016/j.jbior.2020.100784  0.313
2020 Katti S, Nyenhuis SB, Her B, Cafiso DS, Igumenova TI. Partial Metal Ion Saturation of C2 Domains Primes Synaptotagmin 1-Membrane Interactions. Biophysical Journal. PMID 32075747 DOI: 10.1016/J.Bpj.2020.01.032  0.438
2020 Katti S, Igumenova TI. Interference of pH buffer with Pb-peripheral domain interactions: obstacle or opportunity? Metallomics : Integrated Biometal Science. 12: 164-172. PMID 32051983 DOI: 10.1039/D0Mt00002G  0.347
2020 Igumenova TI, Katti S, Yu B, Cole TR. Structural Basis of Protein Kinase C Tumor‐Promoting Response And Membrane Recruitment The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.07150  0.405
2019 You Y, Yu B, Igumenova T, Das J. Lipid Membrane Influences Interaction between the C1 Domain of Munc13-1 and the Activator Biophysical Journal. 116: 517a. DOI: 10.1016/J.Bpj.2018.11.2790  0.39
2018 Cole TR, Erickson S, Morales KA, Sung M, Holzenburg A, Igumenova TI. Cd(II) and Pb(II) induce self-assembly of peripheral membrane domains from protein kinase C. Biochemistry. PMID 30584764 DOI: 10.1021/Acs.Biochem.8B01235  0.432
2018 Katti S, Her B, Srivastava AK, Taylor AB, Lockless SW, Igumenova TI. High affinity interactions of Pb with synaptotagmin I. Metallomics : Integrated Biometal Science. PMID 30063057 DOI: 10.1039/C8Mt00135A  0.398
2018 Yang Y, Shu C, Li P, Igumenova TI. Structural Basis of Protein Kinase Cα Regulation by the C-Terminal Tail. Biophysical Journal. 114: 1590-1603. PMID 29642029 DOI: 10.1016/J.Bpj.2017.12.030  0.474
2018 Igumenova TI, Cole TR, Katti S, Morales KA, Erickson SG, Woo Sung M, Nyenhuis SB, Taylor AB, Hart PJ, Holzenburg A, Cafiso DS. Not Just Ionic Mimicry: Biophysics of Toxic Metal Ion Interactions with Peripheral Membrane Targets Biophysical Journal. 114: 33a. DOI: 10.1016/J.Bpj.2017.11.230  0.303
2017 Katti S, Nyenhuis SB, Her B, Srivastava AK, Taylor AB, Hart PJ, Cafiso DS, Igumenova TI. Non-native metal ion reveals the role of electrostatics in Synaptotagmin 1-membrane interactions. Biochemistry. PMID 28574251 DOI: 10.1021/Acs.Biochem.7B00188  0.421
2017 Stewart MD, Igumenova TI. Toggling of diacylglycerol affinity correlates with conformational plasticity in C1 domains. Biochemistry. PMID 28505428 DOI: 10.1021/Acs.Biochem.7B00228  0.452
2017 Yang Y, Callender JA, Newton AC, Igumenova TI. Structural and Dynamical Basis of Protein Kinase C Alpha Regulation by the C-Terminal Tail Biophysical Journal. 112: 500a. DOI: 10.1016/J.Bpj.2016.11.2704  0.496
2017 Cole TR, Erickson SG, Woo Sung M, Holzenburg A, Igumenova TI. Toxic Metal Ions Promote Self-Association and Replace Structural Zinc Ions in the Regulatory Region of Protein Kinase C Biophysical Journal. 112: 489a-490a. DOI: 10.1016/J.Bpj.2016.11.2648  0.423
2016 Morales KA, Yang Y, Cole TR, Igumenova TI. Dynamic Response of the C2 Domain of Protein Kinase Cα to Ca(2+) Binding. Biophysical Journal. 111: 1655-1667. PMID 27760353 DOI: 10.1016/J.Bpj.2016.09.008  0.467
2015 Igumenova TI. Dynamics and Membrane Interactions of Protein Kinase C. Biochemistry. 54: 4953-68. PMID 26214365 DOI: 10.1021/Acs.Biochem.5B00565  0.391
2015 Ghosh R, de Campos MK, Huang J, Huh SK, Orlowski A, Yang Y, Tripathi A, Nile A, Lee HC, Dynowski M, Schäfer H, Róg T, Lete MG, Ahyayauch H, Alonso A, ... ... Igumenova TI, et al. Sec14-nodulin proteins and the patterning of phosphoinositide landmarks for developmental control of membrane morphogenesis. Molecular Biology of the Cell. 26: 1764-81. PMID 25739452 DOI: 10.1091/Mbc.E14-10-1475  0.341
2015 Cole TR, Igumenova TI. Expression and purification of the N-terminal regulatory domain of Protein Kinase C for biophysical studies. Protein Expression and Purification. 110: 14-21. PMID 25582765 DOI: 10.1016/J.Pep.2014.12.018  0.403
2014 Stewart MD, Cole TR, Igumenova TI. Interfacial partitioning of a loop hinge residue contributes to diacylglycerol affinity of conserved region 1 domains. The Journal of Biological Chemistry. 289: 27653-64. PMID 25124034 DOI: 10.1074/Jbc.M114.585570  0.472
2014 Yang Y, Igumenova TI. The C-Terminal V5 Domain of Protein Kinase Cα is a Multi-Functional Intrinsically Disordered Protein Module Biophysical Journal. 106: 426a. DOI: 10.1016/J.Bpj.2013.11.2399  0.47
2014 Morales KA, Stewart MD, Igumenova TI. NMR of Conditional Peripheral Membrane Proteins Biophysical Journal. 106: 247a-248a. DOI: 10.1016/J.Bpj.2013.11.1451  0.503
2013 Morales KA, Yang Y, Long Z, Li P, Taylor AB, Hart PJ, Igumenova TI. Cd2+ as a Ca2+ surrogate in protein-membrane interactions: isostructural but not isofunctional. Journal of the American Chemical Society. 135: 12980-3. PMID 23937054 DOI: 10.1021/Ja406958K  0.422
2013 Yang Y, Igumenova TI. The C-terminal V5 domain of Protein Kinase Cα is intrinsically disordered, with propensity to associate with a membrane mimetic. Plos One. 8: e65699. PMID 23762412 DOI: 10.1371/Journal.Pone.0065699  0.451
2012 Stewart MD, Igumenova TI. Reactive cysteine in the structural Zn(2+) site of the C1B domain from PKCα. Biochemistry. 51: 7263-77. PMID 22913772 DOI: 10.1021/Bi300750W  0.396
2012 Morales KA, Igumenova TI. Synergistic effect of Pb(2+) and phosphatidylinositol 4,5-bisphosphate on C2 domain-membrane interactions. Biochemistry. 51: 3349-60. PMID 22475207 DOI: 10.1021/Bi201850H  0.507
2011 Morales KA, Lasagna M, Gribenko AV, Yoon Y, Reinhart GD, Lee JC, Cho W, Li P, Igumenova TI. Pb2+ as modulator of protein-membrane interactions. Journal of the American Chemical Society. 133: 10599-611. PMID 21615172 DOI: 10.1021/Ja2032772  0.436
2011 Stewart MD, Morgan B, Massi F, Igumenova TI. Probing the determinants of diacylglycerol binding affinity in the C1B domain of protein kinase Cα. Journal of Molecular Biology. 408: 949-70. PMID 21419781 DOI: 10.1016/J.Jmb.2011.03.020  0.451
2009 Li X, Lu C, Stewart M, Xu H, Strong RK, Igumenova T, Li P. Structural basis of double-stranded RNA recognition by the RIG-I like receptor MDA5. Archives of Biochemistry and Biophysics. 488: 23-33. PMID 19531363 DOI: 10.1016/J.Abb.2009.06.008  0.329
2009 Mosser R, Reddy M, Sacchettini JC, Igumenova T, Reinhart GD. A Solution NMR and Crystallographic Study of the Role of the Quaternary Shift in the Allosteric Regulation of Phosphofructokinase from B. stearothermophilus Biophysical Journal. 96: 5a. DOI: 10.1016/J.Bpj.2008.12.917  0.348
2007 Igumenova TI, Brath U, Akke M, Palmer AG. Characterization of chemical exchange using residual dipolar coupling. Journal of the American Chemical Society. 129: 13396-7. PMID 17929930 DOI: 10.1021/Ja0761636  0.352
2007 Berlow RB, Igumenova TI, Loria JP. Value of a hydrogen bond in triosephosphate isomerase loop motion. Biochemistry. 46: 6001-10. PMID 17455914 DOI: 10.1021/Bi700344V  0.331
2006 Igumenova TI, Palmer AG. Off-resonance TROSY-selected R 1rho experiment with improved sensitivity for medium- and high-molecular-weight proteins. Journal of the American Chemical Society. 128: 8110-1. PMID 16787055 DOI: 10.1021/Ja061692F  0.349
2006 Igumenova TI, Frederick KK, Wand AJ. Characterization of the fast dynamics of protein amino acid side chains using NMR relaxation in solution. Chemical Reviews. 106: 1672-99. PMID 16683749 DOI: 10.1021/Cr040422H  0.378
2005 Igumenova TI, Lee AL, Wand AJ. Backbone and side chain dynamics of mutant calmodulin-peptide complexes. Biochemistry. 44: 12627-39. PMID 16171378 DOI: 10.1021/Bi050832F  0.362
2005 Igumenova TI, McDermott AE. Homo-nuclear 13C J-decoupling in uniformly 13C- enriched solid proteins Journal of Magnetic Resonance. 175: 11-20. PMID 15949744 DOI: 10.1016/J.Jmr.2005.03.007  0.596
2005 Wang T, Frederick KK, Igumenova TI, Wand AJ, Zuiderweg ER. Changes in calmodulin main-chain dynamics upon ligand binding revealed by cross-correlated NMR relaxation measurements. Journal of the American Chemical Society. 127: 828-9. PMID 15656608 DOI: 10.1021/Ja045743P  0.328
2004 Igumenova TI, McDermott AE, Zilm KW, Martin RW, Paulson EK, Wand AJ. Assignments of carbon NMR resonances for microcrystalline ubiquitin. Journal of the American Chemical Society. 126: 6720-7. PMID 15161300 DOI: 10.1021/Ja030547O  0.547
2004 Igumenova TI, Wand AJ, McDermott AE. Assignment of the Backbone Resonances for Microcrystalline Ubiquitin Journal of the American Chemical Society. 126: 5323-5331. PMID 15099118 DOI: 10.1021/Ja030546W  0.588
2003 Igumenova TI, McDermott AE. Improvement of resolution in solid state NMR spectra with J-decoupling: An analysis of lineshape contributions in uniformly 13C-enriched amino acids and proteins Journal of Magnetic Resonance. 164: 270-285. PMID 14511595 DOI: 10.1016/S1090-7807(03)00239-8  0.573
1997 Mitchell DJ, Jakeman DL, Igumenova TI, Shuttleworth WA, Miller KD, Evans JNS. Time-resolved solid-state REDOR-edited NMR detection of a transient enzyme-intermediate Chemical Communications. 1019-1020. DOI: 10.1039/A701926B  0.322
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