Etienne Sibille - Publications

Affiliations: 
University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Genetics of Depression and Aging
Website:
http://www.cnbc.cmu.edu/faculty/sibille.shtml

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Year Citation  Score
2023 Zhang X, Eladawi MA, Ryan WG, Fan X, Prevoznik S, Devale T, Ramnani B, Malathi K, Sibille E, Mccullumsmith R, Tomoda T, Shukla R. Ribosomal dysregulation: A conserved pathophysiological mechanism in human depression and mouse chronic stress. Pnas Nexus. 2: pgad299. PMID 37822767 DOI: 10.1093/pnasnexus/pgad299  0.321
2022 Oh H, Newton D, Lewis D, Sibille E. Lower Levels of GABAergic Function Markers in Corticotropin-Releasing Hormone-Expressing Neurons in the sgACC of Human Subjects With Depression. Frontiers in Psychiatry. 13: 827972. PMID 35280164 DOI: 10.3389/fpsyt.2022.827972  0.303
2021 Shukla R, Newton DF, Sumitomo A, Zare H, Mccullumsmith R, Lewis DA, Tomoda T, Sibille E. Molecular characterization of depression trait and state. Molecular Psychiatry. PMID 34686766 DOI: 10.1038/s41380-021-01347-z  0.305
2021 Miles AE, Dos Santos FC, Byrne EM, Renteria ME, McIntosh AM, Adams MJ, Pistis G, Castelao E, Preisig M, Baune BT, Schubert KO, Lewis CM, Jones LA, Jones I, Uher R, ... ... Sibille E, et al. Transcriptome-based polygenic score links depression-related corticolimbic gene expression changes to sex-specific brain morphology and depression risk. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 34588609 DOI: 10.1038/s41386-021-01189-x  0.32
2021 Wu W, Howard D, Sibille E, French L. Differential and spatial expression meta-analysis of genes identified in genome-wide association studies of depression. Translational Psychiatry. 11: 8. PMID 33414381 DOI: 10.1038/s41398-020-01127-3  0.39
2020 Mareckova K, Hawco C, Dos Santos FC, Bakht A, Calarco N, Miles AE, Voineskos AN, Sibille E, Hariri AR, Nikolova YS. Novel polygenic risk score as a translational tool linking depression-related changes in the corticolimbic transcriptome with neural face processing and anhedonic symptoms. Translational Psychiatry. 10: 410. PMID 33235204 DOI: 10.1038/s41398-020-01093-w  0.311
2020 Lin CW, Chang LC, Ma T, Oh H, French B, Puralewski R, Mathews F, Fang Y, Lewis DA, Kennedy JL, Mueller D, Marshe VS, Jaffe A, Chen Q, Ursini G, ... ... Sibille E, et al. Older molecular brain age in severe mental illness. Molecular Psychiatry. PMID 32632206 DOI: 10.1038/S41380-020-0834-1  0.476
2020 Fee C, Prevot T, Misquitta K, Banasr M, Sibille E. Chronic stress-induced behaviors correlate with exacerbated acute stress-induced cingulate cortex and ventral hippocampus activation. Neuroscience. PMID 32473277 DOI: 10.1016/j.neuroscience.2020.05.034  0.339
2020 Prévot T, Sibille E. Altered GABA-mediated information processing and cognitive dysfunctions in depression and other brain disorders. Molecular Psychiatry. PMID 32346158 DOI: 10.1038/s41380-020-0727-3  0.404
2020 Shukla R, Sumitomo A, Tomoda T, Newton D, McCullumsmith R, Sibille E. Discovering Drugs for Causal Pathways Associated With Major Depressive Disorder Through Drug-Disease Transcriptomic Connectivity Biological Psychiatry. 87. DOI: 10.1016/J.Biopsych.2020.02.706  0.341
2020 Sibille E. Pro-Cognitive and Neurotrophic Effects of a Novel Molecule Enhancing a5-GABA-A Receptor Function in Adult or Aged Mice Biological Psychiatry. 87. DOI: 10.1016/J.Biopsych.2020.02.239  0.31
2020 Prevot T, Li G, Knutson D, Mondal P, Mian Y, Guilloux J, Mendez-David I, David D, Cook J, Sibille E. Improved Cognitive Functions and Neurotrophic Effects of a Novel Molecule Enhancing α5-GABA-A Receptor Function in Adult or Aged Mice Biological Psychiatry. 87: S404. DOI: 10.1016/J.Biopsych.2020.02.1032  0.761
2019 Diniz BS, Reynolds Iii CF, Sibille E, Bot M, Penninx BWJH. Major depression and enhanced molecular senescence abnormalities in young and middle-aged adults. Translational Psychiatry. 9: 198. PMID 31434875 DOI: 10.1038/S41398-019-0541-3  0.405
2019 Shukla R, Oh H, Sibille E. Molecular and Cellular Evidence for Age by Disease Interactions: Updates and Path Forward. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. PMID 31285153 DOI: 10.1016/j.jagp.2019.06.001  0.461
2019 Glorioso CA, Pfenning AR, Lee SS, Bennett DA, Sibille EL, Kellis M, Guarente LP. Rate of brain aging and are synergistic risk factors for Alzheimer's disease. Life Science Alliance. 2. PMID 31133613 DOI: 10.26508/lsa.201900303  0.779
2019 Prevot TD, Misquitta KA, Fee C, Newton DF, Chatterjee D, Nikolova YS, Sibille E, Banasr M. Residual avoidance: A new consistent and repeatable readout of chronic stress-induced conflict anxiety reversible by antidepressant treatment. Neuropharmacology. PMID 31075295 DOI: 10.1016/j.neuropharm.2019.05.005  0.31
2019 Prevot TD, Li G, Cook JM, Sibille E. Insight into Novel Treatment for Cognitive Dysfunctions across Disorders. Acs Chemical Neuroscience. PMID 30920790 DOI: 10.1021/Acschemneuro.9B00148  0.327
2019 DeMichele-Sweet MAA, Weamer EA, Klei L, Vrana DT, Hollingshead DJ, Seltman HJ, Sims R, Foroud T, Hernandez I, Moreno-Grau S, Tárraga L, Boada M, Ruiz A, Williams J, Mayeux R, ... ... Sibille EL, et al. Correction: Genetic risk for schizophrenia and psychosis in Alzheimer disease. Molecular Psychiatry. PMID 30862939 DOI: 10.1038/S41380-019-0373-9  0.405
2019 McKinney BC, Lin CW, Rahman T, Oh H, Lewis DA, Tseng G, Sibille E. DNA methylation in the human frontal cortex reveals a putative mechanism for age-by-disease interactions. Translational Psychiatry. 9: 39. PMID 30696804 DOI: 10.1038/S41398-019-0372-2  0.752
2019 Patel S, Wu W, Sibille E, French L. S38Neuroanatomical Characterization Of Genes Genetically Associated With Depression European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2019.08.039  0.404
2019 Marshe V, Maciukiewicz M, Tiwari AK, Sibille E, Blumberger D, Karp J, Kennedy JL, Mulsant B, Reynolds CF, Lenze EJ, Mueller D. F42Post-Gwas In Silico Biological Characterization Of Variants Associated With Venlafaxine Treatment Remission In Late-Life Depression European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2018.08.122  0.344
2019 Mueller D, Marshe V, Maciukiewicz M, Tiwari A, Kennedy JL, Sibille E, Mulsant B, Reynolds CF, Lenze EJ. Genome-Wide Analyses Of Remission On Venlafaxine Treatment In Older Adults With Late-Life Depression European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2018.07.053  0.315
2019 Marshe V, Maciukiewicz M, Rej S, Tiwari A, Sibille E, Blumberger D, Karp J, Lenze EJ, Reynolds C, Kennedy J, Mulsant B, Mueller D. Unraveling Genomic Contributions To Venlafaxine Remission In Older Adults With Late-Life Depression Using A Genome-Wide Approach European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2017.08.153  0.428
2019 Marshe V, Maciukiewicz M, Hauschild A, Sibille E, Blumberger D, Karp J, Lenze EJ, Reynolds C, Kennedy JL, Mulsant B, Mueller DJ. S79. Predicting Venlafaxine Remission in Late-Life Depression Using Genome-Wide and Clinical Data Biological Psychiatry. 85. DOI: 10.1016/J.Biopsych.2019.03.830  0.312
2019 Prevot T, Li G, Misquitta K, Fee C, Knutson D, Stephen MR, Kodali R, Zahn N, Arnold LA, Banasr M, Cook J, Sibille E. T117. Pro-Cognitive Properties of a Novel GABA-A Receptor Positive Modulator in Animal Models of Depression and Aging Biological Psychiatry. 85: S174. DOI: 10.1016/J.Biopsych.2019.03.440  0.354
2019 Philip V, Newton D, Oh H, Collins S, Bercik P, Sibille E. O54. The Effect of Gut Microbiota on Glutamatergic/GABAergic Gene Expression in Adult Mice Biological Psychiatry. 85. DOI: 10.1016/J.Biopsych.2019.03.319  0.325
2018 Shukla R, Prevot TD, French L, Isserlin R, Rocco BR, Banasr M, Bader GD, Sibille E. The Relative Contributions of Cell-Dependent Cortical Microcircuit Aging to Cognition and Anxiety. Biological Psychiatry. PMID 30446205 DOI: 10.1016/J.Biopsych.2018.09.019  0.381
2018 Sumitomo A, Yukitake H, Hirai K, Horike K, Ueta K, Chung Y, Warabi E, Yanagawa T, Kitaoka S, Furuyashiki T, Narumiya S, Hirano T, Niwa M, Sibille E, Hikida T, et al. Ulk2 controls cortical excitatory-inhibitory balance via autophagic regulation of p62 and GABAA receptor trafficking in pyramidal neurons. Human Molecular Genetics. PMID 29893844 DOI: 10.1093/Hmg/Ddy219  0.355
2018 Nikolova Y, Lin C, Bakht A, Voineskos A, Hariri A, Sibille E. F127. Polygenic Risk for Accelerated Molecular Brain Aging is Associated With Increased Depressive Symptoms and Blunted Corticolimbic Circuit Reactivity Biological Psychiatry. 83. DOI: 10.1016/J.Biopsych.2018.02.740  0.381
2018 Mueller D, Marshe V, Maciukiewicz M, Tiwari AK, Blumberger D, Karp J, Reynolds C, Mulsant B, Lenze EJ, Sibille E, Kennedy J. F120. Genome-Wide Analyses of Venlafaxine Response in Late-Life Depression Biological Psychiatry. 83. DOI: 10.1016/J.Biopsych.2018.02.733  0.302
2018 Banasr M, Prevot T, Misquitta K, Fee C, Newton D, Oh H, Sibille E. T100. Linking GABAergic, Astroglial and Synaptic Dysfunctions to Stress-Induced Depressive-Like Endophenotype: Importance of Astroglial Integrity Biological Psychiatry. 83. DOI: 10.1016/J.Biopsych.2018.02.436  0.329
2018 Sibille E. 256. Targeting GABAergic SST-Positive Interneurons Deficits: Implications for Cognitive and Mood Symptoms in Depression and Other Brain Disorders Biological Psychiatry. 83. DOI: 10.1016/J.Biopsych.2018.02.275  0.37
2017 Scifo E, Pabba M, Kapadia F, Ma T, Lewis DA, Tseng GC, Sibille E. Sustained Molecular Pathology Across Episodes and Remission in Major Depressive Disorder. Biological Psychiatry. PMID 28935211 DOI: 10.1016/J.Biopsych.2017.08.008  0.376
2017 Pabba M, Scifo E, Kapadia F, Nikolova YS, Ma T, Mechawar N, Tseng GC, Sibille E. Resilient protein co-expression network in male orbitofrontal cortex layer 2/3 during human aging. Neurobiology of Aging. 58: 180-190. PMID 28750307 DOI: 10.1016/J.Neurobiolaging.2017.06.023  0.375
2017 Fee C, Banasr M, Sibille E. Somatostatin-Positive Gamma-Aminobutyric Acid Interneuron Deficits in Depression: Cortical Microcircuit and Therapeutic Perspectives. Biological Psychiatry. PMID 28697889 DOI: 10.1016/j.biopsych.2017.05.024  0.381
2017 French L, Ma T, Oh H, Tseng GC, Sibille E. Age-Related Gene Expression in the Frontal Cortex Suggests Synaptic Function Changes in Specific Inhibitory Neuron Subtypes. Frontiers in Aging Neuroscience. 9: 162. PMID 28611654 DOI: 10.3389/fnagi.2017.00162  0.448
2017 DeMichele-Sweet MAA, Weamer EA, Klei L, Vrana DT, Hollingshead DJ, Seltman HJ, Sims R, Foroud T, Hernandez I, Moreno-Grau S, Tárraga L, Boada M, Ruiz A, Williams J, Mayeux R, ... ... Sibille EL, et al. Genetic risk for schizophrenia and psychosis in Alzheimer disease. Molecular Psychiatry. PMID 28461698 DOI: 10.1038/Mp.2017.81  0.412
2017 Sibille E. Reduced Somatostatin Expression or Somatostatin-Positive Gamma-Aminobutyric Acid Neurons: A Shared Pathology Across Brain Disorders. Biological Psychiatry. 81: 467-469. PMID 28190426 DOI: 10.1016/j.biopsych.2016.12.002  0.315
2017 Ferri F, Nikolova YS, Perrucci MG, Costantini M, Ferretti A, Gatta V, Huang Z, Edden RA, Yue Q, D'Aurora M, Sibille E, Stuppia L, Romani GL, Northoff G. A Neural "Tuning Curve" for Multisensory Experience and Cognitive-Perceptual Schizotypy. Schizophrenia Bulletin. PMID 28168302 DOI: 10.1093/Schbul/Sbw174  0.308
2017 Marshe VS, Maciukiewicz M, Rej S, Tiwari AK, Sibille E, Blumberger DM, Karp JF, Lenze EJ, Reynolds CF, Kennedy JL, Mulsant BH, Müller DJ. Norepinephrine Transporter Gene Variants and Remission From Depression With Venlafaxine Treatment in Older Adults. The American Journal of Psychiatry. appiajp201616050617. PMID 28068779 DOI: 10.1176/appi.ajp.2016.16050617  0.368
2017 Nikolova Y, Hariri A, Sibille E. 254. Novel Transcriptome-Based Polygenic Risk Score for Depression is Associated with Reduced dlPFC Efficiency and Disrupted Structural Covariance Network Properties Biological Psychiatry. 81. DOI: 10.1016/J.Biopsych.2017.02.268  0.343
2017 Marshe V, Maciukiewicz M, Rej S, Tiwari AK, Sibille E, Blumberger DM, Karp JF, Lenze EJ, Mulsant BH, Reynolds CF, Kennedy JL, Mueller D. 232. Genome-Wide Association Study of Venlafaxine Treatment Remission in Late-Life Depression Biological Psychiatry. 81. DOI: 10.1016/J.Biopsych.2017.02.246  0.326
2016 Piantadosi SC, French BJ, Poe MM, Timić T, Marković BD, Pabba M, Seney ML, Oh H, Orser BA, Savić MM, Cook JM, Sibille E. Sex-Dependent Anti-Stress Effect of an α5 Subunit Containing GABAA Receptor Positive Allosteric Modulator. Frontiers in Pharmacology. 7: 446. PMID 27920723 DOI: 10.3389/Fphar.2016.00446  0.361
2016 Diniz BS, Reynolds CF, Sibille E, Lin CW, Tseng G, Lotrich F, Aizenstein HJ, Butters MA. Enhanced Molecular Aging in Late-Life Depression: the Senescent-Associated Secretory Phenotype. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. PMID 27856124 DOI: 10.1016/J.Jagp.2016.08.018  0.403
2016 Douillard-Guilloux G, Lewis D, Seney ML, Sibille E. Decrease in somatostatin-positive cell density in the amygdala of females with major depression. Depression and Anxiety. PMID 27557481 DOI: 10.1002/Da.22549  0.41
2016 Grubisha MJ, Lin CW, Tseng GC, Penzes P, Sibille E, Sweet RA. Age-Dependent Increase in Kalirin-9 and Kalirin-12 Transcripts in Human Orbitofrontal Cortex. The European Journal of Neuroscience. PMID 27471199 DOI: 10.1111/Ejn.13351  0.593
2016 Diniz BS, Lin CW, Sibille E, Tseng G, Lotrich F, Aizenstein HJ, Reynolds CF, Butters MA. Circulating biosignatures of late-life depression (LLD): Towards a comprehensive, data-driven approach to understanding LLD pathophysiology. Journal of Psychiatric Research. 82: 1-7. PMID 27447786 DOI: 10.1016/J.Jpsychires.2016.07.006  0.352
2016 Belzeaux R, Lin CW, Ding Y, Bergon A, Ibrahim EC, Turecki G, Tseng G, Sibille E. Predisposition to treatment response in major depressive episode: A peripheral blood gene coexpression network analysis. Journal of Psychiatric Research. 81: 119-126. PMID 27438688 DOI: 10.1016/J.Jpsychires.2016.07.009  0.378
2016 Oh H, Lewis DA, Sibille E. The Role of BDNF in Age-Dependent Changes of Excitatory and Inhibitory Synaptic Markers in Human Prefrontal Cortex. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27417517 DOI: 10.1038/Npp.2016.126  0.449
2016 Zurek AA, Kemp SW, Aga Z, Walker S, Milenkovic M, Ramsey AJ, Sibille E, Scherer SW, Orser BA. α5GABAA receptor deficiency causes autism-like behaviors. Annals of Clinical and Translational Neurology. 3: 392-8. PMID 27231709 DOI: 10.1002/Acn3.303  0.338
2015 Chen CY, Logan RW, Ma T, Lewis DA, Tseng GC, Sibille E, McClung CA. Effects of aging on circadian patterns of gene expression in the human prefrontal cortex. Proceedings of the National Academy of Sciences of the United States of America. PMID 26699485 DOI: 10.1073/Pnas.1508249112  0.452
2015 Nikolova YS, Iruku SP, Lin CW, Conley ED, Puralewski R, French B, Hariri AR, Sibille E. FRAS1-related extracellular matrix 3 (FREM3) single-nucleotide polymorphism effects on gene expression, amygdala reactivity and perceptual processing speed: An accelerated aging pathway of depression risk. Frontiers in Psychology. 6: 1377. PMID 26441752 DOI: 10.3389/Fpsyg.2015.01377  0.41
2015 Ding Y, Chang LC, Wang X, Guilloux JP, Parrish J, Oh H, French BJ, Lewis DA, Tseng GC, Sibille E. Molecular and Genetic Characterization of Depression: Overlap with other Psychiatric Disorders and Aging. Molecular Neuropsychiatry. 1: 1-12. PMID 26213687  0.714
2015 McKinney BC, Lin CW, Oh H, Tseng GC, Lewis DA, Sibille E. Hypermethylation of BDNF and SST Genes in the Orbital Frontal Cortex of Older Individuals: A Putative Mechanism for Declining Gene Expression with Age. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 25881116 DOI: 10.1038/Npp.2015.107  0.727
2015 Bassi S, Seney ML, Argibay P, Sibille E. Elevated Hippocampal Cholinergic Neurostimulating Peptide precursor protein (HCNP-pp) mRNA in the amygdala in major depression. Journal of Psychiatric Research. 63: 105-16. PMID 25819500 DOI: 10.1016/J.Jpsychires.2015.02.006  0.407
2015 Lin CW, Chang LC, Tseng GC, Kirkwood CM, Sibille EL, Sweet RA. VSNL1 Co-Expression Networks in Aging Include Calcium Signaling, Synaptic Plasticity, and Alzheimer's Disease Pathways. Frontiers in Psychiatry. 6: 30. PMID 25806004 DOI: 10.3389/fpsyt.2015.00030  0.519
2015 Lin LC, Sibille E. Transcriptome changes induced by chronic psychosocial/environmental or neuroendocrine stressors reveal a selective cellular vulnerability of cortical somatostatin (SST) neurons, compared with pyramidal (PYR) neurons. Molecular Psychiatry. 20: 285. PMID 25754192 DOI: 10.1038/mp.2015.24  0.486
2015 Lin LC, Sibille E. Somatostatin, neuronal vulnerability and behavioral emotionality. Molecular Psychiatry. 20: 377-87. PMID 25600109 DOI: 10.1038/mp.2014.184  0.588
2015 Guilloux JP, Bassi S, Ding Y, Walsh C, Turecki G, Tseng G, Cyranowski JM, Sibille E. Testing the predictive value of peripheral gene expression for nonremission following citalopram treatment for major depression. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 701-10. PMID 25176167 DOI: 10.1038/Npp.2014.226  0.689
2015 Diniz BS, Sibille E, Ding Y, Tseng G, Aizenstein HJ, Lotrich F, Becker JT, Lopez OL, Lotze MT, Klunk WE, Reynolds CF, Butters MA. Plasma biosignature and brain pathology related to persistent cognitive impairment in late-life depression. Molecular Psychiatry. 20: 594-601. PMID 25092249 DOI: 10.1038/Mp.2014.76  0.348
2014 Tang S, Ding Y, Sibille E, Mogil J, Lariviere WR, Tseng GC. Imputation of Truncated p-Values For Meta-Analysis Methods and Its Genomic Application. The Annals of Applied Statistics. 8: 2150-2174. PMID 25541588 DOI: 10.1214/14-Aoas747  0.31
2014 Seney ML, Tripp A, McCune S, Lewis D, Sibille E. Laminar and cellular analyses of reduced somatostatin gene expression in the subgenual anterior cingulate cortex in major depression. Neurobiology of Disease. 73: 213-219. PMID 25315685 DOI: 10.1016/J.Nbd.2014.10.005  0.392
2014 Nikolova YS, Koenen KC, Galea S, Wang CM, Seney ML, Sibille E, Williamson DE, Hariri AR. Beyond genotype: serotonin transporter epigenetic modification predicts human brain function. Nature Neuroscience. 17: 1153-5. PMID 25086606 DOI: 10.1038/Nn.3778  0.387
2014 Di Narzo AF, Kozlenkov A, Roussos P, Hao K, Hurd Y, Lewis DA, Sibille E, Siever LJ, Koonin E, Dracheva S. A unique gene expression signature associated with serotonin 2C receptor RNA editing in the prefrontal cortex and altered in suicide. Human Molecular Genetics. 23: 4801-13. PMID 24781207 DOI: 10.1093/Hmg/Ddu195  0.423
2014 Soumier A, Sibille E. Opposing effects of acute versus chronic blockade of frontal cortex somatostatin-positive inhibitory neurons on behavioral emotionality in mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 2252-62. PMID 24690741 DOI: 10.1038/npp.2014.76  0.353
2014 Chang LC, Jamain S, Lin CW, Rujescu D, Tseng GC, Sibille E. A conserved BDNF, glutamate- and GABA-enriched gene module related to human depression identified by coexpression meta-analysis and DNA variant genome-wide association studies. Plos One. 9: e90980. PMID 24608543 DOI: 10.1371/journal.pone.0090980  0.488
2014 Gaiteri C, Ding Y, French B, Tseng GC, Sibille E. Beyond modules and hubs: the potential of gene coexpression networks for investigating molecular mechanisms of complex brain disorders. Genes, Brain, and Behavior. 13: 13-24. PMID 24320616 DOI: 10.1111/Gbb.12106  0.688
2013 Seney ML, Ekong KI, Ding Y, Tseng GC, Sibille E. Sex chromosome complement regulates expression of mood-related genes. Biology of Sex Differences. 4: 20. PMID 24199867 DOI: 10.1186/2042-6410-4-20  0.419
2013 Seney ML, Chang LC, Oh H, Wang X, Tseng GC, Lewis DA, Sibille E. The Role of Genetic Sex in Affect Regulation and Expression of GABA-Related Genes Across Species. Frontiers in Psychiatry. 4: 104. PMID 24062698 DOI: 10.3389/Fpsyt.2013.00104  0.435
2013 Lin LC, Sibille E. Reduced brain somatostatin in mood disorders: a common pathophysiological substrate and drug target? Frontiers in Pharmacology. 4: 110. PMID 24058344 DOI: 10.3389/fphar.2013.00110  0.581
2013 Sibille E, French B. Biological substrates underpinning diagnosis of major depression. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 1893-909. PMID 23672886 DOI: 10.1017/S1461145713000436  0.479
2013 Sibille E. Molecular aging of the brain, neuroplasticity, and vulnerability to depression and other brain-related disorders. Dialogues in Clinical Neuroscience. 15: 53-65. PMID 23576889  0.392
2013 Douillard-Guilloux G, Guilloux JP, Lewis DA, Sibille E. Anticipated brain molecular aging in major depression. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 21: 450-60. PMID 23570888 DOI: 10.1016/J.Jagp.2013.01.040  0.726
2013 McKinney BC, Sibille E. The age-by-disease interaction hypothesis of late-life depression. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 21: 418-32. PMID 23570886 DOI: 10.1097/JGP.0b013e31826ce80d  0.759
2013 Sibille E. Will neurobiology rise to the translational challenges and opportunities of late-life geriatric psychiatry? The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 21: 411-4. PMID 23570884 DOI: 10.1016/j.jagp.2013.02.016  0.44
2013 Sibille E. Genomics of depression Access Science. DOI: 10.1036/1097-8542.Yb133335  0.367
2012 McKinney BC, Oh H, Sibille E. Age-by-disease biological interactions: implications for late-life depression. Frontiers in Genetics. 3: 237. PMID 23162569 DOI: 10.3389/fgene.2012.00237  0.761
2012 Tripp A, Oh H, Guilloux JP, Martinowich K, Lewis DA, Sibille E. Brain-derived neurotrophic factor signaling and subgenual anterior cingulate cortex dysfunction in major depressive disorder. The American Journal of Psychiatry. 169: 1194-202. PMID 23128924 DOI: 10.1176/Appi.Ajp.2012.12020248  0.711
2012 Edgar N, Sibille E. A putative functional role for oligodendrocytes in mood regulation. Translational Psychiatry. 2: e109. PMID 22832953 DOI: 10.1038/tp.2012.34  0.793
2012 Wang X, Lin Y, Song C, Sibille E, Tseng GC. Detecting disease-associated genes with confounding variable adjustment and the impact on genomic meta-analysis: with application to major depressive disorder. Bmc Bioinformatics. 13: 52. PMID 22458711 DOI: 10.1186/1471-2105-13-52  0.367
2012 Gaisler-Salomon I, Wang Y, Chuhma N, Zhang H, Golumbic YN, Mihali A, Arancio O, Sibille E, Rayport S. Synaptic underpinnings of altered hippocampal function in glutaminase-deficient mice during maturation. Hippocampus. 22: 1027-39. PMID 22431402 DOI: 10.1002/Hipo.22014  0.371
2012 Seney ML, Walsh C, Stolakis R, Sibille E. Neonatal testosterone partially organizes sex differences in stress-induced emotionality in mice. Neurobiology of Disease. 46: 486-96. PMID 22394611 DOI: 10.1016/J.Nbd.2012.02.014  0.361
2012 Joeyen-Waldorf J, Nikolova YS, Edgar N, Walsh C, Kota R, Lewis DA, Ferrell R, Manuck SB, Hariri AR, Sibille E. Adenylate cyclase 7 is implicated in the biology of depression and modulation of affective neural circuitry. Biological Psychiatry. 71: 627-32. PMID 22264442 DOI: 10.1016/J.Biopsych.2011.11.029  0.808
2012 Kang DD, Sibille E, Kaminski N, Tseng GC. MetaQC: objective quality control and inclusion/exclusion criteria for genomic meta-analysis. Nucleic Acids Research. 40: e15. PMID 22116060 DOI: 10.1093/nar/gkr1071  0.301
2012 Guilloux JP, Douillard-Guilloux G, Kota R, Wang X, Gardier AM, Martinowich K, Tseng GC, Lewis DA, Sibille E. Molecular evidence for BDNF- and GABA-related dysfunctions in the amygdala of female subjects with major depression. Molecular Psychiatry. 17: 1130-42. PMID 21912391 DOI: 10.1038/Mp.2011.113  0.714
2011 Edgar NM, Touma C, Palme R, Sibille E. Resilient emotionality and molecular compensation in mice lacking the oligodendrocyte-specific gene Cnp1. Translational Psychiatry. 1: e42. PMID 22832658 DOI: 10.1038/tp.2011.40  0.809
2011 Gaiteri C, Sibille E. Differentially expressed genes in major depression reside on the periphery of resilient gene coexpression networks. Frontiers in Neuroscience. 5: 95. PMID 21922000 DOI: 10.3389/fnins.2011.00095  0.7
2011 Lin LC, Lewis DA, Sibille E. A human-mouse conserved sex bias in amygdala gene expression related to circadian clock and energy metabolism. Molecular Brain. 4: 18. PMID 21542937 DOI: 10.1186/1756-6606-4-18  0.587
2011 Guilloux JP, Seney M, Edgar N, Sibille E. Integrated behavioral z-scoring increases the sensitivity and reliability of behavioral phenotyping in mice: relevance to emotionality and sex. Journal of Neuroscience Methods. 197: 21-31. PMID 21277897 DOI: 10.1016/J.Jneumeth.2011.01.019  0.771
2011 Tripp A, Kota RS, Lewis DA, Sibille E. Reduced somatostatin in subgenual anterior cingulate cortex in major depression. Neurobiology of Disease. 42: 116-24. PMID 21232602 DOI: 10.1016/J.Nbd.2011.01.014  0.387
2011 Sibille E, Morris HM, Kota RS, Lewis DA. GABA-related transcripts in the dorsolateral prefrontal cortex in mood disorders. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 14: 721-34. PMID 21226980 DOI: 10.1017/S1461145710001616  0.378
2011 Glorioso C, Sibille E. Between destiny and disease: genetics and molecular pathways of human central nervous system aging. Progress in Neurobiology. 93: 165-81. PMID 21130140 DOI: 10.1016/j.pneurobio.2010.11.006  0.795
2011 Glorioso C, Oh S, Douillard GG, Sibille E. Brain molecular aging, promotion of neurological disease and modulation by sirtuin 5 longevity gene polymorphism. Neurobiology of Disease. 41: 279-90. PMID 20887790 DOI: 10.1016/j.nbd.2010.09.016  0.8
2011 Oh S, Tseng GC, Sibille E. Reciprocal phylogenetic conservation of molecular aging in mouse and human brain. Neurobiology of Aging. 32: 1331-5. PMID 19729224 DOI: 10.1016/j.neurobiolaging.2009.08.004  0.427
2010 Gaiteri C, Guilloux JP, Lewis DA, Sibille E. Altered gene synchrony suggests a combined hormone-mediated dysregulated state in major depression. Plos One. 5: e9970. PMID 20376317 DOI: 10.1371/Journal.Pone.0009970  0.81
2010 Guilloux JP, Gaiteri C, Sibille E. Network analysis of positional candidate genes of schizophrenia highlights...more than... myelin-related pathways. Molecular Psychiatry. 15: 786-8. PMID 20351722 DOI: 10.1038/mp.2009.68  0.745
2009 Sibille E, Wang Y, Joeyen-Waldorf J, Gaiteri C, Surget A, Oh S, Belzung C, Tseng GC, Lewis DA. A molecular signature of depression in the amygdala. The American Journal of Psychiatry. 166: 1011-24. PMID 19605536 DOI: 10.1176/Appi.Ajp.2009.08121760  0.794
2009 Joeyen-Waldorf J, Edgar N, Sibille E. The roles of sex and serotonin transporter levels in age- and stress-related emotionality in mice. Brain Research. 1286: 84-93. PMID 19577546 DOI: 10.1016/j.brainres.2009.06.079  0.78
2009 Surget A, Wang Y, Leman S, Ibarguen-Vargas Y, Edgar N, Griebel G, Belzung C, Sibille E. Corticolimbic transcriptome changes are state-dependent and region-specific in a rodent model of depression and of antidepressant reversal. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 1363-80. PMID 18536703 DOI: 10.1038/Npp.2008.76  0.798
2008 Sibille E, Arango V, Joeyen-Waldorf J, Wang Y, Leman S, Surget A, Belzung C, Mann JJ, Lewis DA. Large-scale estimates of cellular origins of mRNAs: enhancing the yield of transcriptome analyses. Journal of Neuroscience Methods. 167: 198-206. PMID 17889939 DOI: 10.1016/J.Jneumeth.2007.08.009  0.731
2007 Sibille E, Su J, Leman S, Le Guisquet AM, Ibarguen-Vargas Y, Joeyen-Waldorf J, Glorioso C, Tseng GC, Pezzone M, Hen R, Belzung C. Lack of serotonin1B receptor expression leads to age-related motor dysfunction, early onset of brain molecular aging and reduced longevity. Molecular Psychiatry. 12: 1042-56, 975. PMID 17420766 DOI: 10.1038/sj.mp.4001990  0.687
2007 Sibille E, Su J, Leman S, Le Guisquet AM, Ibarguen-Vargas Y, Joeyen-Waldorf J, Glorioso C, Tseng GC, Pezzone M, Hen R, Belzung C. Upregulated sirtuin 5 gene expression in frontal cortex of serotonin 1b receptor knock out mice Molecular Psychiatry. 12: 975. DOI: 10.1038/sj.mp.4002115  0.658
2006 Weisstaub NV, Zhou M, Lira A, Lambe E, González-Maeso J, Hornung JP, Sibille E, Underwood M, Itohara S, Dauer WT, Ansorge MS, Morelli E, Mann JJ, Toth M, Aghajanian G, et al. Cortical 5-HT2A receptor signaling modulates anxiety-like behaviors in mice. Science (New York, N.Y.). 313: 536-40. PMID 16873667 DOI: 10.1126/Science.1123432  0.748
2006 Sibille E, Lewis DA. SERT-ainly involved in depression, but when? The American Journal of Psychiatry. 163: 8-11. PMID 16390880 DOI: 10.1176/Appi.Ajp.163.1.8  0.358
2006 Leonardo ED, Richardson-Jones JW, Sibille E, Kottman A, Hen R. Molecular heterogeneity along the dorsal-ventral axis of the murine hippocampal CA1 field: a microarray analysis of gene expression. Neuroscience. 137: 177-86. PMID 16309847 DOI: 10.1016/j.neuroscience.2005.08.082  0.769
2006 Bach-Mizrachi H, Underwood MD, Kassir SA, Bakalian MJ, Sibille E, Tamir H, Mann JJ, Arango V. Neuronal tryptophan hydroxylase mRNA expression in the human dorsal and median raphe nuclei: major depression and suicide. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 814-24. PMID 16192985 DOI: 10.1038/sj.npp.1300897  0.386
2005 Erraji-Benchekroun L, Underwood MD, Arango V, Galfalvy H, Pavlidis P, Smyrniotopoulos P, Mann JJ, Sibille E. Molecular aging in human prefrontal cortex is selective and continuous throughout adult life. Biological Psychiatry. 57: 549-58. PMID 15737671 DOI: 10.1016/J.Biopsych.2004.10.034  0.46
2004 Pavlidis P, Qin J, Arango V, Mann JJ, Sibille E. Using the gene ontology for microarray data mining: a comparison of methods and application to age effects in human prefrontal cortex. Neurochemical Research. 29: 1213-22. PMID 15176478 DOI: 10.1023/B:NERE.0000023608.29741.45  0.405
2004 Sibille E, Arango V, Galfalvy HC, Pavlidis P, Erraji-Benchekroun L, Ellis SP, John Mann J. Gene expression profiling of depression and suicide in human prefrontal cortex. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 351-61. PMID 14603265 DOI: 10.1038/sj.npp.1300335  0.485
2003 Galfalvy HC, Erraji-Benchekroun L, Smyrniotopoulos P, Pavlidis P, Ellis SP, Mann JJ, Sibille E, Arango V. Sex genes for genomic analysis in human brain: internal controls for comparison of probe level data extraction. Bmc Bioinformatics. 4: 37. PMID 12962547 DOI: 10.1186/1471-2105-4-37  0.395
2001 Sibille E, Hen R. Serotonin(1A) receptors in mood disorders: a combined genetic and genomic approach. Behavioural Pharmacology. 12: 429-38. PMID 11742136  0.551
2001 Sibille E, Hen R. Combining genetic and genomic approaches to study mood disorders. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 11: 413-21. PMID 11704418 DOI: 10.1016/S0924-977X(01)00118-3  0.563
2001 Santarelli L, Gobbi G, Debs PC, Sibille ET, Blier P, Hen R, Heath MJ. Genetic and pharmacological disruption of neurokinin 1 receptor function decreases anxiety-related behaviors and increases serotonergic function. Proceedings of the National Academy of Sciences of the United States of America. 98: 1912-7. PMID 11172050 DOI: 10.1073/Pnas.98.4.1912  0.493
2000 Sibille E, Pavlides C, Benke D, Toth M. Genetic Inactivation of the Serotonin1AReceptor in Mice Results in Downregulation of Major GABAAReceptor α Subunits, Reduction of GABAAReceptor Binding, and Benzodiazepine-Resistant Anxiety The Journal of Neuroscience. 20: 2758-2765. DOI: 10.1523/JNEUROSCI.20-08-02758.2000  0.322
1998 Parks CL, Robinson PS, Sibille E, Shenk T, Toth M. Increased anxiety of mice lacking the serotonin1A receptor. Proceedings of the National Academy of Sciences of the United States of America. 95: 10734-9. PMID 9724773 DOI: 10.1073/pnas.95.18.10734  0.326
1997 Sibille E, Sarnyai Z, Benjamin D, Gal J, Baker H, Toth M. Antisense inhibition of 5-hydroxytryptamine2a receptor induces an antidepressant-like effect in mice. Molecular Pharmacology. 52: 1056-63. PMID 9415715 DOI: 10.1124/MOL.52.6.1056  0.315
Low-probability matches (unlikely to be authored by this person)
2021 Tomoda T, Sumitomo A, Shukla R, Hirota-Tsuyada Y, Miyachi H, Oh H, French L, Sibille E. BDNF controls GABAR trafficking and related cognitive processes via autophagic regulation of p62. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 34341497 DOI: 10.1038/s41386-021-01116-0  0.297
2018 Oh H, Piantadosi SC, Rocco BR, Lewis DA, Watkins SC, Sibille E. The Role of Dendritic Brain-Derived Neurotrophic Factor Transcripts on Altered Inhibitory Circuitry in Depression. Biological Psychiatry. PMID 30449530 DOI: 10.1016/J.Biopsych.2018.09.026  0.297
2017 Banasr M, Nikolova Y, Misquitta K, Rocco B, Prevot T, Knodt A, Hariri A, Voineskos A, Ellegood J, Lerch JP, Sibille E. 154. Behavioral and Brain Network Adaptations to Chronic Stress, A Translational Study Biological Psychiatry. 81. DOI: 10.1016/J.Biopsych.2017.02.167  0.296
2010 Gaisler-Salomon I, Wang Y, McKinney SM, Ramsey AJ, Sibille E, Rayport S. ADULT-ONSET GLUTAMATE RECEPTOR EXPRESSION DEFICITS IN THE HIPPOCAMPUS OF GLUTAMINASE-DEFICIENT MICE Schizophrenia Research. 117: 389. DOI: 10.1016/j.schres.2010.02.701  0.296
1997 Donovan GP, Harden C, Gal J, Ho L, Sibille E, Trifiletti R, Gudas LJ, Toth M. Sensitivity to jerky gene dosage underlies epileptic seizures in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 4562-9. PMID 9169517 DOI: 10.1523/Jneurosci.17-12-04562.1997  0.291
2013 Chang LC, Lin HM, Sibille E, Tseng GC. Meta-analysis methods for combining multiple expression profiles: comparisons, statistical characterization and an application guideline. Bmc Bioinformatics. 14: 368. PMID 24359104 DOI: 10.1186/1471-2105-14-368  0.29
2018 Lissemore JI, Bhandari A, Mulsant BH, Lenze EJ, Reynolds CF, Karp JF, Rajji TK, Noda Y, Zomorrodi R, Sibille E, Daskalakis ZJ, Blumberger DM. Reduced GABAergic cortical inhibition in aging and depression. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 29849055 DOI: 10.1038/S41386-018-0093-X  0.288
2017 Rocco BR, Oh H, Shukla R, Mechawar N, Sibille E. Fluorescence-based cell-specific detection for laser-capture microdissection in human brain. Scientific Reports. 7: 14213. PMID 29079825 DOI: 10.1038/S41598-017-14484-9  0.288
2012 Wang X, Kang DD, Shen K, Song C, Lu S, Chang LC, Liao SG, Huo Z, Tang S, Ding Y, Kaminski N, Sibille E, Lin Y, Li J, Tseng GC. An R package suite for microarray meta-analysis in quality control, differentially expressed gene analysis and pathway enrichment detection. Bioinformatics (Oxford, England). 28: 2534-6. PMID 22863766 DOI: 10.1093/Bioinformatics/Bts485  0.287
2018 Gunduz-Cinar O, Brockway E, Lederle L, Wilcox T, Halladay LR, Ding Y, Oh H, Busch EF, Kaugars K, Flynn S, Limoges A, Bukalo O, MacPherson KP, Masneuf S, Pinard C, ... Sibille E, et al. Identification of a novel gene regulating amygdala-mediated fear extinction. Molecular Psychiatry. PMID 29311651 DOI: 10.1038/S41380-017-0003-3  0.285
2023 Chen Y, Hunter E, Arbabi K, Guet-McCreight A, Consens M, Felsky D, Sibille E, Tripathy SJ. Robust differences in cortical cell type proportions across healthy human aging inferred through cross-dataset transcriptome analyses. Neurobiology of Aging. 125: 49-61. PMID 36841202 DOI: 10.1016/j.neurobiolaging.2023.01.013  0.282
2019 Bani-Fatemi A, Sibille E, Luca VD. T172. Short-Term Stress and DNA Methylation of Hypothalamic-Pituitary-Adrenal Axis Genes in Triggering or Worsening Suicidal Ideation: Association Analysis in Schizophrenia Biological Psychiatry. 85. DOI: 10.1016/J.Biopsych.2019.03.495  0.281
2017 Rocco B, Shukla R, Oh H, Sibille E. 157. Novel Methods for Assessing Cell-Type Specific Differences in Human Brain Biological Psychiatry. 81. DOI: 10.1016/J.Biopsych.2017.02.170  0.281
1999 Chen L, He M, Sibille E, Thompson A, Sarnyai Z, Baker H, Shippenberg T, Toth M. Adaptive changes in postsynaptic dopamine receptors despite unaltered dopamine dynamics in mice lacking monoamine oxidase B. Journal of Neurochemistry. 73: 647-55. PMID 10428061 DOI: 10.1046/J.1471-4159.1999.0730647.X  0.28
2009 Romcy-Pereira RN, Erraji-Benchekroun L, Smyrniotopoulos P, Ogawa S, Mello CV, Sibille E, Pavlides C. Sleep-dependent gene expression in the hippocampus and prefrontal cortex following long-term potentiation. Physiology & Behavior. 98: 44-52. PMID 19389414 DOI: 10.1016/j.physbeh.2009.04.010  0.279
2018 Ma T, Huo Z, Kuo A, Zhu L, Fang Z, Zeng X, Lin CW, Liu S, Wang L, Liu P, Rahman T, Chang LC, Kim S, Li J, Park Y, ... ... Sibille E, et al. MetaOmics: Analysis Pipeline and Browser-based Software Suite for Transcriptomic Meta-Analysis. Bioinformatics (Oxford, England). PMID 30304367 DOI: 10.1093/Bioinformatics/Bty825  0.279
2001 He M, Sibille E, Benjamin D, Toth M, Shippenberg T. Differential effects of 5-HT1A receptor deletion upon basal and fluoxetine-evoked 5-HT concentrations as revealed by in vivo microdialysis. Brain Research. 902: 11-7. PMID 11376590 DOI: 10.1016/S0006-8993(01)02271-5  0.279
2022 Yao HK, Guet-McCreight A, Mazza F, Moradi Chameh H, Prevot TD, Griffiths JD, Tripathy SJ, Valiante TA, Sibille E, Hay E. Reduced inhibition in depression impairs stimulus processing in human cortical microcircuits. Cell Reports. 38: 110232. PMID 35021088 DOI: 10.1016/j.celrep.2021.110232  0.278
2011 Kupfer DJ, Angst J, Berk M, Dickerson F, Frangou S, Frank E, Goldstein BI, Harvey A, Laghrissi-Thode F, Leboyer M, Ostacher MJ, Sibille E, Strakowski SM, Suppes T, Tohen M, et al. Advances in bipolar disorder: selected sessions from the 2011 International Conference on Bipolar Disorder. Annals of the New York Academy of Sciences. 1242: 1-25. PMID 22191553 DOI: 10.1111/J.1749-6632.2011.06336.X  0.273
2023 Sumitomo A, Zhou R, Prevot T, Sibille E, Tomoda T. BS3 Chemical Crosslinking Assay: Evaluating the Effect of Chronic Stress on Cell Surface GABAA Receptor Presentation in the Rodent Brain. Journal of Visualized Experiments : Jove. PMID 37306428 DOI: 10.3791/65063  0.273
2021 Seney ML, Glausier J, Sibille E. Large-Scale Transcriptomics Studies Provide Insight Into Sex Differences in Depression. Biological Psychiatry. PMID 33648716 DOI: 10.1016/j.biopsych.2020.12.025  0.27
2019 Sibille E, Cook J. Lifting Brain Fog Scientia. DOI: 10.33548/Scientia384  0.27
2017 Banasr M, Lepack A, Fee C, Duric V, Maldonado-Aviles J, DiLeone R, Sibille E, Duman RS, Sanacora G. Characterization of GABAergic marker expression in the chronic unpredictable stress model of depression. Chronic Stress (Thousand Oaks, Calif.). 1. PMID 28835932  0.269
2021 Marshe VS, Maciukiewicz M, Hauschild AC, Islam F, Qin L, Tiwari AK, Sibille E, Blumberger DM, Karp JF, Flint AJ, Turecki G, Lam RW, Milev RV, Frey BN, Rotzinger S, et al. Genome-wide analysis suggests the importance of vascular processes and neuroinflammation in late-life antidepressant response. Translational Psychiatry. 11: 127. PMID 33589590 DOI: 10.1038/s41398-021-01248-3  0.269
2019 Newton D, Oh H, Shukla R, Fee C, Bader G, Banasr M, Sibille E. T120. Transcriptomic Analysis of Cortical Microcircuit Cell-Types Reveals Differential Cellular Vulnerabilities and Adaptations to Chronic Stress Biological Psychiatry. 85. DOI: 10.1016/J.Biopsych.2019.03.443  0.267
2018 Nikolova YS, Misquitta KA, Rocco BR, Prevot TD, Knodt AR, Ellegood J, Voineskos AN, Lerch JP, Hariri AR, Sibille E, Banasr M. Shifting priorities: highly conserved behavioral and brain network adaptations to chronic stress across species. Translational Psychiatry. 8: 26. PMID 29353879 DOI: 10.1038/s41398-017-0083-5  0.265
2014 Northoff G, Sibille E. Why are cortical GABA neurons relevant to internal focus in depression? A cross-level model linking cellular, biochemical and neural network findings. Molecular Psychiatry. 19: 966-77. PMID 25048001 DOI: 10.1038/mp.2014.68  0.264
2023 Luscher B, Maguire JL, Rudolph U, Sibille E. GABA receptors as targets for treating affective and cognitive symptoms of depression. Trends in Pharmacological Sciences. PMID 37543478 DOI: 10.1016/j.tips.2023.06.009  0.262
2018 Sibille E. 91. Investigating Molecular Homeostasis in Cortical Microcircuits in Health and Disease Biological Psychiatry. 83. DOI: 10.1016/J.Biopsych.2018.02.108  0.261
2017 Maluach AM, Misquitta KA, Prevot TD, Fee C, Sibille E, Banasr M, Andreazza AC. Increased Neuronal DNA/RNA Oxidation in the Frontal Cortex of Mice Subjected to Unpredictable Chronic Mild Stress. Chronic Stress (Thousand Oaks, Calif.). 1. PMID 29250610  0.259
2023 Clifford KP, Miles AE, Prevot TD, Misquitta KA, Ellegood J, Lerch JP, Sibille E, Nikolova YS, Banasr M. Brain structure and working memory adaptations associated with maturation and aging in mice. Frontiers in Aging Neuroscience. 15: 1195748. PMID 37484693 DOI: 10.3389/fnagi.2023.1195748  0.258
2023 Banasr M, Codeluppi S, Xu M, Bansal Y, Lepack A, Duric V, Chow M, Muir J, Bagot R, Licznerski P, Wilber S, Sanacora G, Sibille E, Duman R, Pittenger C. Prefrontal Cortex Astroglia Modulate Anhedonia-like Behavior. Research Square. PMID 37461693 DOI: 10.21203/rs.3.rs-3093428/v1  0.258
2018 Prevot T, Li G, Vidojevic A, Santrac A, Misquitta K, Hu X, Knutson D, Arnold L, Fisher J, Banasr M, Cook J, Savic M, Sibille E. S162. Antidepressant and Pro-Cognitive Effects of a Novel Series of GABA-A Receptor Positive Allosteric Modulators With α5 Subunit Efficacy Properties Biological Psychiatry. 83: S411. DOI: 10.1016/J.Biopsych.2018.02.1054  0.257
2012 D'Aiuto L, Di Maio R, Heath B, Raimondi G, Milosevic J, Watson AM, Bamne M, Parks WT, Yang L, Lin B, Miki T, Mich-Basso JD, Arav-Boger R, Sibille E, Sabunciyan S, et al. Human induced pluripotent stem cell-derived models to investigate human cytomegalovirus infection in neural cells. Plos One. 7: e49700. PMID 23209593 DOI: 10.1371/Journal.Pone.0049700  0.257
2021 Philip V, Newton DF, Oh H, Collins SM, Bercik P, Sibille E. Transcriptional markers of excitation-inhibition balance in germ-free mice show region-specific dysregulation and rescue after bacterial colonization. Journal of Psychiatric Research. 135: 248-255. PMID 33508544 DOI: 10.1016/j.jpsychires.2021.01.021  0.254
2023 Bansal Y, Fee C, Misquitta KA, Codeluppi SA, Sibille E, Berman RM, Coric V, Sanacora G, Banasr M. Prophylactic Efficacy of Riluzole against Anxiety- and Depressive-Like Behaviors in Two Rodent Stress Models. Complex Psychiatry. 9: 57-69. PMID 37101541 DOI: 10.1159/000529534  0.254
2022 Ibrahim EC, Gorgievski V, Ortiz-Teba P, Belzeaux R, Turecki G, Sibille E, Charbonnier G, Tzavara ET. Transcriptomic Studies of Antidepressant Action in Rodent Models of Depression: A First Meta-Analysis. International Journal of Molecular Sciences. 23. PMID 36362329 DOI: 10.3390/ijms232113543  0.251
2018 Bani-Fatemi A, Tasmim S, Wang KZ, Warsh J, Sibille E, De Luca V. No interaction between polygenic scores and childhood trauma in predicting suicide attempt in schizophrenia. Progress in Neuro-Psychopharmacology & Biological Psychiatry. PMID 30149093 DOI: 10.1016/J.Pnpbp.2018.08.027  0.249
2019 Prevot TD, Li G, Vidojevic A, Misquitta KA, Fee C, Santrac A, Knutson DE, Stephen MR, Kodali R, Zahn NM, Arnold LA, Scholze P, Fisher JL, Marković BD, Banasr M, ... ... Sibille E, et al. Novel Benzodiazepine-Like Ligands with Various Anxiolytic, Antidepressant, or Pro-Cognitive Profiles. Molecular Neuropsychiatry. 5: 84-97. PMID 31192221 DOI: 10.1159/000496086  0.248
2019 Hess J, Tylee D, Liu C, de Jong S, Ophoff R, Gardiner E, Sibille E, Turecki G, Tseng G, Tsuang MT, Faraone S, Glatt S. M14 DISCRIMINATION OF MAJOR NEUROPSYCHIATRIC DISORDERS USING BLOOD-BASED TRANSCRIPTOMIC SIGNATURES European Neuropsychopharmacology. 29: S173. DOI: 10.1016/J.Euroneuro.2019.08.114  0.245
2019 Hu X, Rocco BR, Fee C, Sibille E. Cell Type-Specific Gene Expression of Alpha 5 Subunit-Containing Gamma-Aminobutyric Acid Subtype A Receptors in Human and Mouse Frontal Cortex. Molecular Neuropsychiatry. 4: 204-215. PMID 30815456 DOI: 10.1159/000495840  0.24
2021 Fee C, Prevot TD, Misquitta K, Knutson DE, Li G, Mondal P, Cook JM, Banasr M, Sibille E. Behavioral deficits induced by somatostatin-positive GABA neuron silencing are rescued by alpha 5 GABA-A receptor potentiation. The International Journal of Neuropsychopharmacology. PMID 33438026 DOI: 10.1093/ijnp/pyab002  0.238
2019 Dada O, Bani-Fatemi A, Sibille E, Luca VD. S182. Effect of Adverse Life Events on Global Methylation and Perceived Stress in Schizophrenia Biological Psychiatry. 85. DOI: 10.1016/J.Biopsych.2019.03.933  0.237
2023 Sharmin D, Mian MY, Marcotte M, Prevot TD, Sibille E, Witkin JM, Cook JM. Synthesis and Receptor Binding Studies of α5 GABAR Selective Novel Imidazodiazepines Targeted for Psychiatric and Cognitive Disorders. Molecules (Basel, Switzerland). 28. PMID 37375326 DOI: 10.3390/molecules28124771  0.234
2003 Liu W, Seto J, Sibille E, Toth M. The RNA binding domain of Jerky consists of tandemly arranged helix-turn-helix/homeodomain-like motifs and binds specific sets of mRNAs. Molecular and Cellular Biology. 23: 4083-93. PMID 12773553 DOI: 10.1128/MCB.23.12.4083-4093.2003  0.234
2020 Prevot TD, Sumitomo A, Tomoda T, Knutson DE, Li G, Mondal P, Banasr M, Cook JM, Sibille E. Reversal of Age-Related Neuronal Atrophy by α5-GABAA Receptor Positive Allosteric Modulation. Cerebral Cortex (New York, N.Y. : 1991). PMID 33068001 DOI: 10.1093/cercor/bhaa310  0.232
2014 Seney ML, Sibille E. Sex differences in mood disorders: perspectives from humans and rodent models. Biology of Sex Differences. 5: 17. PMID 25520774 DOI: 10.1186/S13293-014-0017-3  0.23
2021 Mareckova K, Hawco C, Santos FCD, Bakht A, Calarco N, Miles AE, Voineskos AN, Sibille E, Hariri AR, Nikolova YS. Correction: Novel polygenic risk score as a translational tool linking depression-related changes in the corticolimbic transcriptome with neural face processing and anhedonic symptoms. Translational Psychiatry. 11: 152. PMID 33654052 DOI: 10.1038/s41398-021-01277-y  0.227
2005 Barr GA, Gao P, Wang S, Cheng J, Qin J, Sibille EL, Pavlidis P. Microarray analysis of gene expression following the formalin test in the infant rat. Pain. 117: 6-18. PMID 16043289 DOI: 10.1016/J.Pain.2005.04.024  0.226
2014 D'Aiuto L, Di Maio R, Heath B, Raimondi G, Milosevic J, Watson AM, Bamne M, Parks WT, Yang L, Lin B, Miki T, Mich-Basso JD, Arav-Boger R, Sibille E, Sabunciyan S, et al. Correction: Human Induced Pluripotent Stem Cell-Derived Models to Investigate Human Cytomegalovirus Infection in Neural Cells Plos One. 9. DOI: 10.1371/Annotation/Ea66E8F1-9F80-422F-8836-308A4Cdc8Ae4  0.225
2019 Wang K, Sibille E, Luca VD. T166. Effect of Genome-Wide Methylation Changes on Emergent Suicidal Ideation Biological Psychiatry. 85. DOI: 10.1016/J.Biopsych.2019.03.489  0.224
2022 Mendes-Silva AP, Prevot TD, Banasr M, Sibille E, Diniz BS. Abnormal expression of cortical cell cycle regulators underlying anxiety and depressive-like behavior in mice exposed to chronic stress. Frontiers in Cellular Neuroscience. 16: 999303. PMID 36568887 DOI: 10.3389/fncel.2022.999303  0.224
2024 Guet-McCreight A, Chameh HM, Mazza F, Prevot TD, Valiante TA, Sibille E, Hay E. In-silico testing of new pharmacology for restoring inhibition and human cortical function in depression. Communications Biology. 7: 225. PMID 38396202 DOI: 10.1038/s42003-024-05907-1  0.224
2014 French B, Seney ML, Sibille E. Altered gaba function in major depression Synaptic Stress and Pathogenesis of Neuropsychiatric Disorders. 223-244. DOI: 10.1007/978-1-4939-1056-4_13  0.216
2014 Diniz BS, Reynolds CF, Begley A, Dew MA, Anderson SJ, Lotrich F, Erickson KI, Lopez O, Aizenstein H, Sibille EL, Butters MA. Brain-derived neurotrophic factor levels in late-life depression and comorbid mild cognitive impairment: a longitudinal study. Journal of Psychiatric Research. 49: 96-101. PMID 24290367 DOI: 10.1016/J.Jpsychires.2013.11.004  0.213
2021 Oh H, Prevot TD, Newton D, Sibille E. From serendipity to rational drug design in brain disorders: in silico, in vitro, and in vivo approaches. Current Opinion in Pharmacology. 60: 177-182. PMID 34461562 DOI: 10.1016/j.coph.2021.07.012  0.208
2018 Seney ML, Huo Z, Cahill K, French L, Puralewski R, Zhang J, Logan RW, Tseng G, Lewis DA, Sibille E. Opposite Molecular Signatures of Depression in Men and Women. Biological Psychiatry. PMID 29548746 DOI: 10.1016/J.Biopsych.2018.01.017  0.205
2014 Northoff G, Sibille E. Cortical GABA neurons and self-focus in depression: a model linking cellular, biochemical and neural network findings. Molecular Psychiatry. 19: 959. PMID 25237734 DOI: 10.1038/mp.2014.108  0.203
2011 Almeida JR, Kronhaus DM, Sibille EL, Langenecker SA, Versace A, Labarbara EJ, Phillips ML. Abnormal left-sided orbitomedial prefrontal cortical-amygdala connectivity during happy and fear face processing: a potential neural mechanism of female MDD. Frontiers in Psychiatry. 2: 69. PMID 22163223 DOI: 10.3389/Fpsyt.2011.00069  0.2
2021 Newton DF, Oh H, Shukla R, Misquitta K, Fee C, Banasr M, Sibille E. Chronic Stress Induces Coordinated Cortical Microcircuit Cell-Type Transcriptomic Changes Consistent With Altered Information Processing. Biological Psychiatry. PMID 34861977 DOI: 10.1016/j.biopsych.2021.10.015  0.2
2021 Misquitta KA, Miles A, Prevot TD, Knoch JK, Fee C, Newton DF, Ellegood J, Lerch JP, Sibille E, Nikolova YS, Banasr M. Reduced anterior cingulate cortex volume induced by chronic stress correlates with increased behavioral emotionality and decreased synaptic puncta density. Neuropharmacology. 108562. PMID 33864799 DOI: 10.1016/j.neuropharm.2021.108562  0.195
2021 Kraimi N, De Palma G, Lu J, Bowdish D, Verdu E, Sibille E, Prevot T, Collins SM, Bercik P. A238 ABSENCE OF AGE-RELATED MEMORY DECLINE IN GERM-FREE MICE Journal of the Canadian Association of Gastroenterology. 4: 288-289. DOI: 10.1093/JCAG/GWAB002.236  0.187
2022 Bernardo A, Lee P, Marcotte M, Mian MY, Rezvanian S, Sharmin D, Kovačević A, Savić MM, Cook JM, Sibille E, Prevot TD. Symptomatic and neurotrophic effects of GABAA receptor positive allosteric modulation in a mouse model of chronic stress. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 35701547 DOI: 10.1038/s41386-022-01360-y  0.186
2015 Pabba M, Sibille E. GABA, Depression and Suicide Advances in Biological Psychiatry. 30: 37-50. DOI: 10.1159/000434736  0.181
2018 Caravaggio F, Scifo E, Sibille EL, Hernandez-Da Mota SE, Gerretsen P, Remington G, Graff-Guerrero A. Expression of dopamine D2 and D3 receptors in the human retina revealed by positron emission tomography and targeted mass spectrometry. Experimental Eye Research. PMID 29883636 DOI: 10.1016/J.Exer.2018.06.006  0.171
2023 Zong W, Rahman T, Zhu L, Zeng X, Zhang Y, Zou J, Liu S, Ren Z, Li JJ, Sibille E, Lee AV, Oesterreich S, Ma T, Tseng GC. Transcriptomic congruence analysis for evaluating model organisms. Proceedings of the National Academy of Sciences of the United States of America. 120: e2202584120. PMID 36730203 DOI: 10.1073/pnas.2202584120  0.171
2000 Sibille E, Pavlides C, Benke D, Toth M. Genetic inactivation of the Serotonin(1A) receptor in mice results in downregulation of major GABA(A) receptor alpha subunits, reduction of GABA(A) receptor binding, and benzodiazepine-resistant anxiety. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 2758-65. PMID 10751426  0.17
2021 Codeluppi SA, Chatterjee D, Prevot TD, Bansal Y, Misquitta KA, Sibille E, Banasr M. Chronic Stress Alters Astrocyte Morphology in Mouse Prefrontal Cortex. The International Journal of Neuropsychopharmacology. PMID 34346493 DOI: 10.1093/ijnp/pyab052  0.17
2018 Li G, Stephen MR, Kodali R, Zahn NM, Poe MM, Tiruveedhula VVNPB, Huber AT, Schussman MK, Qualmann K, Panhans CM, Raddatz NJ, Baker DA, Prevot TD, Banasr M, Sibille E, et al. Synthesis of chiral GABAA receptor subtype selective ligands as potential agents to treat schizophrenia as well as depression Arkivoc. 2018: 158-182. DOI: 10.24820/ark.5550190.p010.460  0.164
2023 McCoy AM, Prevot TD, Sharmin D, Cook JM, Sibille EL, Lodge DJ. GL-II-73, a Positive Allosteric Modulator of α5GABA Receptors, Reverses Dopamine System Dysfunction Associated with Pilocarpine-Induced Temporal Lobe Epilepsy. International Journal of Molecular Sciences. 24. PMID 37511346 DOI: 10.3390/ijms241411588  0.161
2017 Mancarci BO, Toker L, Tripathy SJ, Li B, Rocco B, Sibille E, Pavlidis P. Cross-Laboratory Analysis of Brain Cell Type Transcriptomes with Applications to Interpretation of Bulk Tissue Data. Eneuro. 4. PMID 29204516 DOI: 10.1523/ENEURO.0212-17.2017  0.16
2024 McCoy AM, Prevot TD, Mian MY, Sharmin D, Ahmad AN, Cook JM, Sibille EL, Lodge DJ. Extrasynaptic localization is essential for α5GABA receptor modulation of dopamine system function. Eneuro. PMID 38413199 DOI: 10.1523/ENEURO.0344-23.2023  0.158
2022 Tomoda T, Sumitomo A, Newton D, Sibille E. Molecular origin of somatostatin-positive neuron vulnerability. Molecular Psychiatry. PMID 35145229 DOI: 10.1038/s41380-022-01463-4  0.152
2021 Marcotte M, Bernardo A, Linga N, Pérez-Romero CA, Guillou JL, Sibille E, Prevot TD. Handling Techniques to Reduce Stress in Mice. Journal of Visualized Experiments : Jove. PMID 34633376 DOI: 10.3791/62593  0.146
2022 McCoy AM, Prevot TD, Mian MY, Cook JM, Frazer A, Sibille EL, Carreno FR, Lodge DJ. Positive allosteric modulation of α5-GABAA receptors reverses stress-induced alterations in dopamine system function and prepulse inhibition of startle. The International Journal of Neuropsychopharmacology. PMID 35732272 DOI: 10.1093/ijnp/pyac035  0.144
2000 Sarnyai Z, Sibille EL, Pavlides C, Fenster RJ, McEwen BS, Toth M. Impaired hippocampal-dependent learning and functional abnormalities in the hippocampus in mice lacking serotonin(1A) receptors. Proceedings of the National Academy of Sciences of the United States of America. 97: 14731-6. PMID 11121072 DOI: 10.1073/Pnas.97.26.14731  0.144
2018 Li G, Stephen MR, Kodali R, Zahn NM, Poe MM, Tiruveedhula VVNPB, Huber AT, Schussman MK, Qualmann K, Panhans CM, Raddatz NJ, Baker DA, Prevot TD, Banasr M, Sibille E, et al. Synthesis of chiral GABA receptor subtype selective ligands as potential agents to treat schizophrenia as well as depression. Arkivoc : Free Online Journal of Organic Chemistry. 2018: 158-182. PMID 32774192 DOI: 10.24820/Ark.5550190.P010.460  0.132
2015 Pabba M, Sibille E. Sigma-1 and N-Methyl-d-Aspartate Receptors: A Partnership with Beneficial Outcomes. Molecular Neuropsychiatry. 1: 47-51. PMID 27602356 DOI: 10.1159/000376549  0.125
2021 Sicherman J, Newton DF, Pavlidis P, Sibille E, Tripathy SJ. Estimating and Correcting for Off-Target Cellular Contamination in Brain Cell Type Specific RNA-Seq Data. Frontiers in Molecular Neuroscience. 14: 637143. PMID 33746712 DOI: 10.3389/fnmol.2021.637143  0.121
2024 Rezaei S, Prévot TD, Vieira E, Sibille E. LPS-induced inflammation reduces GABAergic interneuron markers and brain-derived neurotrophic factor in mouse prefrontal cortex and hippocampus. Brain, Behavior, & Immunity - Health. 38: 100761. PMID 38586282 DOI: 10.1016/j.bbih.2024.100761  0.12
2022 Perez SM, McCoy AM, Prevot TD, Mian MY, Carreno FR, Frazer A, Cook JM, Sibille E, Lodge DJ. Hippocampal α5-GABA Receptors Modulate Dopamine Neuron Activity in the Rat Ventral Tegmental Area. Biological Psychiatry Global Open Science. 3: 78-86. PMID 36712569 DOI: 10.1016/j.bpsgos.2021.12.010  0.119
2023 McCoy AM, Prevot TD, Mian MY, Sharmin D, Ahmad AN, Cook JM, Sibille EL, Lodge DJ. Extrasynaptic localization is essential for α5GABA receptor modulation of dopamine system function. Biorxiv : the Preprint Server For Biology. PMID 37502875 DOI: 10.1101/2023.07.12.548744  0.113
2015 Masson EA, Sibille E, Martine L, Chaux-Picquet F, Bretillon L, Berdeaux O. Apprehending ganglioside diversity: a comprehensive methodological approach. Journal of Lipid Research. 56: 1821-35. PMID 26142958 DOI: 10.1194/jlr.D060764  0.111
1996 Toth M, Sibille E, Gyulai Z, Gal J. Genetic approaches to elucidate serotonin2A (5HT2A) receptor function Biological Psychiatry. 39: 532. DOI: 10.1016/0006-3223(96)84061-3  0.107
2006 Sarnyai Z, Sibille EL, Pavlides C, Fenster RJ, McEwen BS, Toth M. Functional Abnormalities in the Hippocampus and Impaired Hippocampal-dependent Learning in Mice Lacking the 5HT1A Receptors Cns Drug Reviews. 6: 40-40. DOI: 10.1111/J.1527-3458.2000.Tb00183.X  0.095
2023 Dharavath RN, Pina-Leblanc C, Tang VM, Sloan ME, Nikolova YS, Pangarov P, Ruocco AC, Shield K, Voineskos D, Blumberger DM, Boileau I, Bozinoff N, Gerretsen P, Vieira E, Melamed OC, ... Sibille E, et al. GABAergic signaling in alcohol use disorder and withdrawal: pathological involvement and therapeutic potential. Frontiers in Neural Circuits. 17: 1218737. PMID 37929054 DOI: 10.3389/fncir.2023.1218737  0.079
1997 Donovan GP, Harden C, Gal J, Ho L, Sibille E, Trifiletti R, Gudas LJ, Toth M. Sensitivity toJerkyGene Dosage Underlies Epileptic Seizures in Mice The Journal of Neuroscience. 17: 4562-4569. DOI: 10.1523/JNEUROSCI.17-12-04562.1997  0.075
2022 Prevot TD, Sibille E. Neurotrophic effects of potentiating gaba-mediated dendritic inhibition. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 35995974 DOI: 10.1038/s41386-022-01423-0  0.075
2015 Bana E, Sibille E, Valente S, Cerella C, Chaimbault P, Kirsch G, Dicato M, Diederich M, Bagrel D. A novel coumarin-quinone derivative SV37 inhibits CDC25 phosphatases, impairs proliferation, and induces cell death. Molecular Carcinogenesis. 54: 229-41. PMID 24155226 DOI: 10.1002/mc.22094  0.074
2012 Sibille E, Bana E, Chaouni W, Diederich M, Bagrel D, Chaimbault P. Development of a matrix-assisted laser desorption/ionization-mass spectrometry screening test to evidence reversible and irreversible inhibitors of CDC25 phosphatases. Analytical Biochemistry. 430: 83-91. PMID 22902804 DOI: 10.1016/j.ab.2012.08.006  0.072
2009 Schneider S, Sibille E, Yegles M, Neels H, Wennig R, Mühe A. Time resolved analysis of risperidone and 9-hydroxy-risperidone in hair using LC/MS-MS. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 877: 2589-92. PMID 19595645 DOI: 10.1016/J.Jchromb.2009.06.035  0.07
2015 Kamarulzaman EE, Gazzali AM, Acherar S, Frochot C, Barberi-Heyob M, Boura C, Chaimbault P, Sibille E, Wahab HA, Vanderesse R. New Peptide-Conjugated Chlorin-Type Photosensitizer Targeting Neuropilin-1 for Anti-Vascular Targeted Photodynamic Therapy. International Journal of Molecular Sciences. 16: 24059-80. PMID 26473840 DOI: 10.3390/Ijms161024059  0.054
2010 Tripp A, Sibille E. SERT models of emotional dysregulation Experimental Models in Serotonin Transporter Research. 105-134. DOI: 10.1017/CBO9780511729935.005  0.053
2013 Eddaya T, Boughdad A, Sibille E, Chaimbault P, Zaid A, Amechrouq A. Biological activity of Sapindus mukorossi Gaerten (Sapindaceae) aqueous extract against Thysanoplusia orichalcea (Lepidoptera: Noctuidae) Industrial Crops and Products. 50: 325-332. DOI: 10.1016/j.indcrop.2013.07.045  0.024
1984 Cerisola G, Braggio E, Bonora PL, Sibille E. HYDROGEN EVOLUTION INDUCED DEFECTS ON PRECOATED STEELS DURING CATHAPHORETIC ELECTRODEPOSITION Organic Coatings, Science and Technology. 265-283.  0.014
2013 Moussaron A, Arnoux P, Vanderesse R, Sibille E, Chaimbault P, Frochot C. Lipophilic phthalocyanines for their potential interest in photodynamic therapy: Synthesis and photo-physical properties Tetrahedron. 69: 10116-10122. DOI: 10.1016/j.tet.2013.09.035  0.012
2004 Blandin N, Brunat W, Neuhaus R, Sibille E. Trends in the automotive paint industry for corrosion protection Eurocorr 2004 - European Corrosion Conference: Long Term Prediction and Modelling of Corrosion 0.01
1963 Edwards WR, Sibille EC. Mixed carboxylic anhydrides in the Friedel-Crafts reaction Journal of Organic Chemistry. 28: 674-679.  0.01
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