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Nicholas A. Furlotte, Ph.D. - Publications

Affiliations: 
2013 Computer Science 0201 University of California, Los Angeles, Los Angeles, CA 
Area:
bioinformatics; computational biology; machine learning
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40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 McCaw ZR, Colthurst T, Yun T, Furlotte NA, Carroll A, Alipanahi B, McLean CY, Hormozdiari F. DeepNull models non-linear covariate effects to improve phenotypic prediction and association power. Nature Communications. 13: 241. PMID 35017556 DOI: 10.1038/s41467-021-27930-0  0.305
2021 Simcoe M, Valdes A, Liu F, Furlotte NA, Evans DM, Hemani G, Ring SM, Smith GD, Duffy DL, Zhu G, Gordon SD, Medland SE, Vuckovic D, Girotto G, Sala C, et al. Genome-wide association study in almost 195,000 individuals identifies 50 previously unidentified genetic loci for eye color. Science Advances. 7. PMID 33692100 DOI: 10.1126/sciadv.abd1239  0.368
2020 Elson SL, Furlotte NA, Hromatka BS, Wilson CH, Mountain JL, Rowbotham HM, Varga EA, Francke U. Direct-to-consumer genetic testing for factor V Leiden and prothrombin 20210G>A: the consumer experience. Molecular Genetics & Genomic Medicine. e1468. PMID 32940023 DOI: 10.1002/Mgg3.1468  0.332
2019 Gazal S, Finucane HK, Furlotte NA, Loh PR, Palamara PF, Liu X, Schoech A, Bulik-Sullivan B, Neale BM, Gusev A, Price AL. Author Correction: Linkage disequilibrium-dependent architecture of human complex traits shows action of negative selection. Nature Genetics. PMID 31273336 DOI: 10.1038/S41588-019-0468-X  0.327
2019 Hysi PG, Valdes AM, Liu F, Furlotte NA, Evans DM, Bataille V, Visconti A, Hemani G, McMahon G, Ring SM, Smith GD, Duffy DL, Zhu G, Gordon SD, Medland SE, et al. Publisher Correction: Genome-wide association meta-analysis of individuals of European ancestry identifies new loci explaining a substantial fraction of hair color variation and heritability. Nature Genetics. PMID 31150021 DOI: 10.1038/S41588-019-0446-3  0.435
2019 Turley P, Walters RK, Maghzian O, Okbay A, Lee JJ, Fontana MA, Nguyen-Viet TA, Wedow R, Zacher M, Furlotte NA, Magnusson P, Oskarsson S, Johannesson M, et al. Publisher Correction: Multi-trait analysis of genome-wide association summary statistics using MTAG. Nature Genetics. PMID 31147634 DOI: 10.1038/S41588-019-0444-5  0.435
2018 Broman KW, Gatti DM, Simecek P, Furlotte NA, Prins P, Sen Ś, Yandell BS, Churchill GA. R/qtl2: Software for Mapping Quantitative Trait Loci with High-Dimensional Data and Multi-parent Populations. Genetics. PMID 30591514 DOI: 10.1534/Genetics.118.301595  0.443
2018 Ioannidis NM, Wang W, Furlotte NA, Hinds DA, Bustamante CD, Jorgenson E, Asgari MM, Whittemore AS. Gene expression imputation identifies candidate genes and susceptibility loci associated with cutaneous squamous cell carcinoma. Nature Communications. 9: 4264. PMID 30323283 DOI: 10.1038/S41467-018-06149-6  0.467
2018 Lee JJ, Wedow R, Okbay A, Kong E, Maghzian O, Zacher M, Nguyen-Viet TA, Bowers P, Sidorenko J, Karlsson Linnér R, Fontana MA, Kundu T, Lee C, Li H, Li R, ... ... Furlotte NA, et al. Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. Nature Genetics. PMID 30038396 DOI: 10.1038/S41588-018-0147-3  0.429
2018 Anttila V, Bulik-Sullivan B, Finucane HK, Walters RK, Bras J, Duncan L, Escott-Price V, Falcone GJ, Gormley P, Malik R, Patsopoulos NA, Ripke S, Wei Z, Yu D, ... ... Furlotte N, et al. Analysis of shared heritability in common disorders of the brain. Science (New York, N.Y.). 360. PMID 29930110 DOI: 10.1126/Science.Aap8757  0.348
2018 Kang EY, Lee CH, Furlotte NA, Joo JWJ, Kostem E, Zaitlen N, Eskin E, Han B. An Association Mapping Framework To Account for Potential Sex Difference in Genetic Architectures. Genetics. PMID 29752291 DOI: 10.1534/Genetics.117.300501  0.742
2018 Hysi PG, Valdes AM, Liu F, Furlotte NA, Evans DM, Bataille V, Visconti A, Hemani G, McMahon G, Ring SM, Smith GD, Duffy DL, Zhu G, Gordon SD, Medland SE, et al. Genome-wide association meta-analysis of individuals of European ancestry identifies new loci explaining a substantial fraction of hair color variation and heritability. Nature Genetics. PMID 29662168 DOI: 10.1038/S41588-018-0100-5  0.483
2018 Turley P, Walters RK, Maghzian O, Okbay A, Lee JJ, Fontana MA, Nguyen-Viet TA, Wedow R, Zacher M, Furlotte NA, Magnusson P, Oskarsson S, Johannesson M, Visscher PM, Laibson D, et al. Multi-trait analysis of genome-wide association summary statistics using MTAG. Nature Genetics. PMID 29292387 DOI: 10.1038/S41588-017-0009-4  0.485
2017 Gazal S, Finucane HK, Furlotte NA, Loh PR, Palamara PF, Liu X, Schoech A, Bulik-Sullivan B, Neale BM, Gusev A, Price AL. Linkage disequilibrium-dependent architecture of human complex traits shows action of negative selection. Nature Genetics. PMID 28892061 DOI: 10.1038/Ng.3954  0.426
2016 Okbay A, Baselmans BM, De Neve JE, Turley P, Nivard MG, Fontana MA, Meddens SF, Linnér RK, Rietveld CA, Derringer J, Gratten J, Lee JJ, Liu JZ, de Vlaming R, Ahluwalia TS, ... ... Furlotte NA, et al. Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses. Nature Genetics. 48: 1591. PMID 27898078 DOI: 10.1038/Ng1216-1587B  0.398
2016 Gormley P, Anttila V, Winsvold BS, Palta P, Esko T, Pers TH, Farh KH, Cuenca-Leon E, Muona M, Furlotte NA, Kurth T, Ingason A, McMahon G, Ligthart L, Terwindt GM, et al. Corrigendum: Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine. Nature Genetics. 48: 1296. PMID 27681292 DOI: 10.1038/Ng1016-1296C  0.392
2016 Okbay A, Baselmans BM, Neve JE, Turley P, Nivard MG, Fontana MA, Meddens SF, Linnér RK, Rietveld CA, Derringer J, Gratten J, Lee JJ, Liu JZ, de Vlaming R, Ahluwalia TS, ... ... Furlotte NA, et al. Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses. Nature Genetics. 48: 970. PMID 27463399 DOI: 10.1038/ng0816-970c  0.307
2016 Jones AV, Hockley JR, Hyde C, Gorman D, Sredic-Rhodes A, Bilsland J, McMurray G, Furlotte NA, Hu Y, Hinds DA, Cox PJ, Scollen S. Genome-wide association analysis of pain severity in dysmenorrhea identifies association at chromosome 1p13.2, near the nerve growth factor locus. Pain. PMID 27454463 DOI: 10.1097/J.Pain.0000000000000678  0.356
2016 Gormley P, Anttila V, Winsvold BS, Palta P, Esko T, Pers TH, Farh KH, Cuenca-Leon E, Muona M, Furlotte NA, Kurth T, Ingason A, McMahon G, Ligthart L, Terwindt GM, et al. Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine. Nature Genetics. PMID 27322543 DOI: 10.1038/Ng.3598  0.474
2016 Okbay A, Beauchamp JP, Fontana MA, Lee JJ, Pers TH, Rietveld CA, Turley P, Chen GB, Emilsson V, Meddens SF, Oskarsson S, Pickrell JK, Thom K, Timshel P, de Vlaming R, ... ... Furlotte NA, et al. Genome-wide association study identifies 74 loci associated with educational attainment. Nature. 533: 539-42. PMID 27225129 DOI: 10.1038/Nature17671  0.487
2016 Okbay A, Baselmans BM, De Neve JE, Turley P, Nivard MG, Fontana MA, Meddens SF, Linnér RK, Rietveld CA, Derringer J, Gratten J, Lee JJ, Liu JZ, de Vlaming R, Ahluwalia TS, ... ... Furlotte NA, et al. Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses. Nature Genetics. PMID 27089181 DOI: 10.1038/Ng.3552  0.432
2016 Sul JH, Bilow M, Yang WY, Kostem E, Furlotte N, He D, Eskin E. Accounting for Population Structure in Gene-by-Environment Interactions in Genome-Wide Association Studies Using Mixed Models. Plos Genetics. 12: e1005849. PMID 26943367 DOI: 10.1371/Journal.Pgen.1005849  0.755
2016 Sloan Z, Arends D, W. Broman K, Centeno A, Furlotte N, Nijveen H, Yan L, Zhou X, W. Williams R, Prins P. GeneNetwork: framework for web-based genetics The Journal of Open Source Software. 1: 25. DOI: 10.21105/Joss.00025  0.416
2015 Orozco LD, Morselli M, Rubbi L, Guo W, Go J, Shi H, Lopez D, Furlotte NA, Bennett BJ, Farber CR, Ghazalpour A, Zhang MQ, Bahous R, Rozen R, Lusis AJ, et al. Epigenome-wide association of liver methylation patterns and complex metabolic traits in mice. Cell Metabolism. 21: 905-17. PMID 26039453 DOI: 10.1016/J.Cmet.2015.04.025  0.447
2015 Furlotte NA, Eskin E. Efficient multiple-trait association and estimation of genetic correlation using the matrix-variate linear mixed model. Genetics. 200: 59-68. PMID 25724382 DOI: 10.1534/Genetics.114.171447  0.711
2015 Joo JWJ, Kang EY, Org E, Furlotte N, Parks B, Lusis AJ, Eskin E. Efficient and accurate multiple-phenotypes regression method for high dimensional data considering population structure Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 9029: 136-153. DOI: 10.1007/978-3-319-16706-0_15  0.678
2014 He D, Furlotte NA, Hormozdiari F, Joo JW, Wadia A, Ostrovsky R, Sahai A, Eskin E. Identifying genetic relatives without compromising privacy. Genome Research. 24: 664-72. PMID 24614977 DOI: 10.1101/Gr.153346.112  0.701
2014 Kang EY, Han B, Furlotte N, Joo JW, Shih D, Davis RC, Lusis AJ, Eskin E. Meta-analysis identifies gene-by-environment interactions as demonstrated in a study of 4,965 mice. Plos Genetics. 10: e1004022. PMID 24415945 DOI: 10.1371/Journal.Pgen.1004022  0.782
2012 Ghazalpour A, Rau CD, Farber CR, Bennett BJ, Orozco LD, van Nas A, Pan C, Allayee H, Beaven SW, Civelek M, Davis RC, Drake TA, Friedman RA, Furlotte N, Hui ST, et al. Hybrid mouse diversity panel: a panel of inbred mouse strains suitable for analysis of complex genetic traits. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 23: 680-92. PMID 22892838 DOI: 10.1007/S00335-012-9411-5  0.776
2012 Furlotte NA, Eskin E, Eyheramendy S. Genome-wide association mapping with longitudinal data. Genetic Epidemiology. 36: 463-71. PMID 22581622 DOI: 10.1002/Gepi.21640  0.696
2012 Furlotte NA, Kang EY, Van Nas A, Farber CR, Lusis AJ, Eskin E. Increasing association mapping power and resolution in mouse genetic studies through the use of meta-analysis for structured populations. Genetics. 191: 959-67. PMID 22505625 DOI: 10.1534/Genetics.112.140277  0.781
2011 Keane TM, Goodstadt L, Danecek P, White MA, Wong K, Yalcin B, Heger A, Agam A, Slater G, Goodson M, Furlotte NA, Eskin E, NellÃ¥ker C, Whitley H, Cleak J, et al. Mouse genomic variation and its effect on phenotypes and gene regulation. Nature. 477: 289-94. PMID 21921910 DOI: 10.1038/Nature10413  0.613
2011 Ghazalpour A, Bennett B, Petyuk VA, Orozco L, Hagopian R, Mungrue IN, Farber CR, Sinsheimer J, Kang HM, Furlotte N, Park CC, Wen PZ, Brewer H, Weitz K, Camp DG, et al. Comparative analysis of proteome and transcriptome variation in mouse. Plos Genetics. 7: e1001393. PMID 21695224 DOI: 10.1371/Journal.Pgen.1001393  0.587
2011 Furlotte NA, Kang HM, Ye C, Eskin E. Mixed-model coexpression: calculating gene coexpression while accounting for expression heterogeneity. Bioinformatics (Oxford, England). 27: i288-94. PMID 21685083 DOI: 10.1093/bioinformatics/btr221  0.626
2011 Van Tyne D, Park DJ, Schaffner SF, Neafsey DE, Angelino E, Cortese JF, Barnes KG, Rosen DM, Lukens AK, Daniels RF, Milner DA, Johnson CA, Shlyakhter I, Grossman SR, Becker JS, ... ... Furlotte NA, et al. Identification and functional validation of the novel antimalarial resistance locus PF10_0355 in Plasmodium falciparum. Plos Genetics. 7: e1001383. PMID 21533027 DOI: 10.1371/Journal.Pgen.1001383  0.615
2011 He D, Hormozdiari F, Furlotte N, Eskin E. Efficient algorithms for tandem copy number variation reconstruction in repeat-rich regions. Bioinformatics (Oxford, England). 27: 1513-20. PMID 21505028 DOI: 10.1093/Bioinformatics/Btr169  0.655
2011 Farber CR, Bennett BJ, Orozco L, Zou W, Lira A, Kostem E, Kang HM, Furlotte N, Berberyan A, Ghazalpour A, Suwanwela J, Drake TA, Eskin E, Wang QT, Teitelbaum SL, et al. Mouse genome-wide association and systems genetics identify Asxl2 as a regulator of bone mineral density and osteoclastogenesis. Plos Genetics. 7: e1002038. PMID 21490954 DOI: 10.1371/Journal.Pgen.1002038  0.765
2010 He D, Furlotte N, Eskin E. Detection and reconstruction of tandemly organized de novo copy number variations. Bmc Bioinformatics. 11: S12. PMID 21172047 DOI: 10.1186/1471-2105-11-S11-S12  0.65
2010 Kirby A, Kang HM, Wade CM, Cotsapas C, Kostem E, Han B, Furlotte N, Kang EY, Rivas M, Bogue MA, Frazer KA, Johnson FM, Beilharz EJ, Cox DR, Eskin E, et al. Fine mapping in 94 inbred mouse strains using a high-density haplotype resource. Genetics. 185: 1081-95. PMID 20439770 DOI: 10.1534/Genetics.110.115014  0.76
2010 Bennett BJ, Farber CR, Orozco L, Kang HM, Ghazalpour A, Siemers N, Neubauer M, Neuhaus I, Yordanova R, Guan B, Truong A, Yang WP, He A, Kayne P, Gargalovic P, ... ... Furlotte N, et al. A high-resolution association mapping panel for the dissection of complex traits in mice. Genome Research. 20: 281-90. PMID 20054062 DOI: 10.1101/Gr.099234.109  0.799
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