Nir Yosef - Publications

Affiliations: 
Electrical Engineering and Computer Science University of California, Berkeley, Berkeley, CA, United States 
Area:
Biosystems & Computational Biology (BIO)

95 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Wang C, Wagner A, Fessler J, DeTomaso D, Zaghouani S, Zhou Y, Pierce K, Sobel RA, Clish C, Yosef N, Kuchroo VK. The glycolytic reaction PGAM unexpectedly restrains Th17 pathogenicity and Th17-dependent autoimmunity. Biorxiv : the Preprint Server For Biology. PMID 39229227 DOI: 10.1101/2024.08.18.607992  0.332
2023 Prillo S, Ravoor A, Yosef N, Song YS. ConvexML: Scalable and accurate inference of single-cell chronograms from CRISPR/Cas9 lineage tracing data. Biorxiv : the Preprint Server For Biology. PMID 38076815 DOI: 10.1101/2023.12.03.569785  0.374
2023 Gayoso A, Weiler P, Lotfollahi M, Klein D, Hong J, Streets A, Theis FJ, Yosef N. Deep generative modeling of transcriptional dynamics for RNA velocity analysis in single cells. Nature Methods. PMID 37735568 DOI: 10.1038/s41592-023-01994-w  0.323
2023 Steier Z, Aylard DA, McIntyre LL, Baldwin I, Kim EJY, Lutes LK, Ergen C, Huang TS, Robey EA, Yosef N, Streets A. Single-cell multiomic analysis of thymocyte development reveals drivers of CD4 T cell and CD8 T cell lineage commitment. Nature Immunology. PMID 37580604 DOI: 10.1038/s41590-023-01584-0  0.307
2023 Ashuach T, Gabitto MI, Koodli RV, Saldi GA, Jordan MI, Yosef N. MultiVI: deep generative model for the integration of multimodal data. Nature Methods. PMID 37386189 DOI: 10.1038/s41592-023-01909-9  0.314
2023 Boyeau P, Regier J, Gayoso A, Jordan MI, Lopez R, Yosef N. An empirical Bayes method for differential expression analysis of single cells with deep generative models. Proceedings of the National Academy of Sciences of the United States of America. 120: e2209124120. PMID 37192164 DOI: 10.1073/pnas.2209124120  0.389
2023 Wang R, Zhang R, Khodaverdian A, Yosef N. Theoretical guarantees for phylogeny inference from single-cell lineage tracing. Proceedings of the National Academy of Sciences of the United States of America. 120: e2203352120. PMID 36927151 DOI: 10.1073/pnas.2203352120  0.304
2022 Pawlak M, DeTomaso D, Schnell A, Meyer Zu Horste G, Lee Y, Nyman J, Dionne D, Regan BML, Singh V, Delorey T, Schramm MA, Wang C, Wallrapp A, Burkett PR, Riesenfeld SJ, ... ... Yosef N, et al. Induction of a colitogenic phenotype in Th1-like cells depends on interleukin-23 receptor signaling. Immunity. PMID 36070768 DOI: 10.1016/j.immuni.2022.08.007  0.31
2022 Buen Abad Najar CF, Burra P, Yosef N, Lareau LF. Identifying cell state-associated alternative splicing events and their coregulation. Genome Research. PMID 35858747 DOI: 10.1101/gr.276109.121  0.675
2022 Worley MI, Everetts NJ, Yasutomi R, Chang RJ, Saretha S, Yosef N, Hariharan IK. Ets21C sustains a pro-regenerative transcriptional program in blastema cells of Drosophila imaginal discs. Current Biology : Cb. PMID 35820420 DOI: 10.1016/j.cub.2022.06.040  0.342
2022 Jones RC, Karkanias J, Krasnow MA, Pisco AO, Quake SR, Salzman J, Yosef N, Bulthaup B, Brown P, Harper W, Hemenez M, Ponnusamy R, Salehi A, Sanagavarapu BA, Spallino E, ... ... Yosef N, et al. The Tabula Sapiens: A multiple-organ, single-cell transcriptomic atlas of humans. Science (New York, N.Y.). 376: eabl4896. PMID 35549404 DOI: 10.1126/science.abl4896  0.398
2022 Jones MG, Rosen Y, Yosef N. Interactive, integrated analysis of single-cell transcriptomic and phylogenetic data with PhyloVision. Cell Reports Methods. 2: 100200. PMID 35497495 DOI: 10.1016/j.crmeth.2022.100200  0.343
2022 Ashuach T, Reidenbach DA, Gayoso A, Yosef N. PeakVI: A deep generative model for single-cell chromatin accessibility analysis. Cell Reports Methods. 2: 100182. PMID 35475224 DOI: 10.1016/j.crmeth.2022.100182  0.347
2022 Lopez R, Li B, Keren-Shaul H, Boyeau P, Kedmi M, Pilzer D, Jelinski A, Yofe I, David E, Wagner A, Ergen C, Addadi Y, Golani O, Ronchese F, Jordan MI, ... ... Yosef N, et al. DestVI identifies continuums of cell types in spatial transcriptomics data. Nature Biotechnology. PMID 35449415 DOI: 10.1038/s41587-022-01272-8  0.42
2022 Tsao HW, Kaminski J, Kurachi M, Barnitz RA, DiIorio MA, LaFleur MW, Ise W, Kurosaki T, Wherry EJ, Haining WN, Yosef N. Batf-mediated epigenetic control of effector CD8 T cell differentiation. Science Immunology. 7: eabi4919. PMID 35179948 DOI: 10.1126/sciimmunol.abi4919  0.373
2022 Gayoso A, Lopez R, Xing G, Boyeau P, Valiollah Pour Amiri V, Hong J, Wu K, Jayasuriya M, Mehlman E, Langevin M, Liu Y, Samaran J, Misrachi G, Nazaret A, Clivio O, ... ... Yosef N, et al. A Python library for probabilistic analysis of single-cell omics data. Nature Biotechnology. PMID 35132262 DOI: 10.1038/s41587-021-01206-w  0.378
2022 Bangs DJ, Tsitsiklis A, Steier Z, Chan SW, Kaminski J, Streets A, Yosef N, Robey EA. CXCR3 regulates stem and proliferative CD8+ T cells during chronic infection by promoting interactions with DCs in splenic bridging channels. Cell Reports. 38: 110266. PMID 35045305 DOI: 10.1016/j.celrep.2021.110266  0.308
2022 Gupta A, Shamsi F, Altemose N, Dorlhiac GF, Cypess AM, White AP, Yosef N, Patti ME, Tseng YH, Streets A. Characterization of transcript enrichment and detection bias in single-nucleus RNA-seq for mapping of distinct human adipocyte lineages. Genome Research. PMID 35042723 DOI: 10.1101/gr.275509.121  0.394
2021 Morrow AK, Hughes JW, Singh J, Joseph AD, Yosef N. Epitome: predicting epigenetic events in novel cell types with multi-cell deep ensemble learning. Nucleic Acids Research. PMID 34379786 DOI: 10.1093/nar/gkab676  0.357
2021 Wagner A, Wang C, Fessler J, DeTomaso D, Avila-Pacheco J, Kaminski J, Zaghouani S, Christian E, Thakore P, Schellhaass B, Akama-Garren E, Pierce K, Singh V, Ron-Harel N, Douglas VP, ... ... Yosef N, et al. Metabolic modeling of single Th17 cells reveals regulators of autoimmunity. Cell. PMID 34216539 DOI: 10.1016/j.cell.2021.05.045  0.306
2021 Everetts NJ, Worley MI, Yasutomi R, Yosef N, Hariharan IK. Single-cell transcriptomics of the wing disc reveals instructive epithelium-to-myoblast interactions. Elife. 10. PMID 33749594 DOI: 10.7554/eLife.61276  0.42
2021 Gayoso A, Steier Z, Lopez R, Regier J, Nazor KL, Streets A, Yosef N. Joint probabilistic modeling of single-cell multi-omic data with totalVI. Nature Methods. PMID 33589839 DOI: 10.1038/s41592-020-01050-x  0.403
2021 Xu C, Lopez R, Mehlman E, Regier J, Jordan MI, Yosef N. Probabilistic harmonization and annotation of single-cell transcriptomics data with deep generative models. Molecular Systems Biology. 17: e9620. PMID 33491336 DOI: 10.15252/msb.20209620  0.418
2020 Sungnak W, Wagner A, Kowalczyk MS, Bod L, Kye YC, Sage PT, Sharpe AH, Sobel RA, Quintana FJ, Rozenblatt-Rosen O, Regev A, Wang C, Yosef N, Kuchroo VK. T Follicular Regulatory Cell-Derived Fibrinogen-like Protein 2 Regulates Production of Autoantibodies and Induction of Systemic Autoimmunity. Journal of Immunology (Baltimore, Md. : 1950). PMID 33168576 DOI: 10.4049/jimmunol.2000748  0.414
2020 Gordon MG, Inoue F, Martin B, Schubach M, Agarwal V, Whalen S, Feng S, Zhao J, Ashuach T, Ziffra R, Kreimer A, Georgakopoulous-Soares I, Yosef N, Ye CJ, Pollard KS, et al. lentiMPRA and MPRAflow for high-throughput functional characterization of gene regulatory elements. Nature Protocols. PMID 32641802 DOI: 10.1038/S41596-020-0333-5  0.416
2020 Buen Abad Najar CF, Yosef N, Lareau LF. Coverage-dependent bias creates the appearance of binary splicing in single cells. Elife. 9. PMID 32597758 DOI: 10.7554/Elife.54603  0.667
2020 Fischer J, Song YS, Yosef N, di Iulio J, Churchman LS, Choder M. The yeast exoribonuclease Xrn1 and associated factors modulate RNA polymerase II processivity in 5' and 3' gene regions. The Journal of Biological Chemistry. PMID 32518159 DOI: 10.1074/Jbc.Ra120.013426  0.421
2020 Jones MG, Khodaverdian A, Quinn JJ, Chan MM, Hussmann JA, Wang R, Xu C, Weissman JS, Yosef N. Inference of single-cell phylogenies from lineage tracing data using Cassiopeia. Genome Biology. 21: 92. PMID 32290857 DOI: 10.1186/S13059-020-02000-8  0.428
2020 Svensson V, Gayoso A, Yosef N, Pachter L. Interpretable factor models of single-cell RNA-seq via variational autoencoders. Bioinformatics (Oxford, England). PMID 32176273 DOI: 10.1093/Bioinformatics/Btaa169  0.572
2020 Schafflick D, Xu CA, Hartlehnert M, Cole M, Schulte-Mecklenbeck A, Lautwein T, Wolbert J, Heming M, Meuth SG, Kuhlmann T, Gross CC, Wiendl H, Yosef N, Meyer Zu Horste G. Integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis. Nature Communications. 11: 247. PMID 31937773 DOI: 10.1038/S41467-019-14118-W  0.442
2019 Inoue F, Kreimer A, Ashuach T, Ahituv N, Yosef N. Identification and Massively Parallel Characterization of Regulatory Elements Driving Neural Induction. Cell Stem Cell. PMID 31631012 DOI: 10.1016/J.Stem.2019.09.010  0.476
2019 DeTomaso D, Jones MG, Subramaniam M, Ashuach T, Ye CJ, Yosef N. Functional interpretation of single cell similarity maps. Nature Communications. 10: 4376. PMID 31558714 DOI: 10.1038/S41467-019-12235-0  0.514
2019 Ashuach T, Fischer DS, Kreimer A, Ahituv N, Theis FJ, Yosef N. MPRAnalyze: statistical framework for massively parallel reporter assays. Genome Biology. 20: 183. PMID 31477158 DOI: 10.1186/S13059-019-1787-Z  0.339
2019 Afik S, Raulet G, Yosef N. Reconstructing B-cell receptor sequences from short-read single-cell RNA sequencing with BRAPeS. Life Science Alliance. 2. PMID 31451449 DOI: 10.26508/lsa.201900371  0.35
2019 Zhang X, Xu C, Yosef N. Simulating multiple faceted variability in single cell RNA sequencing. Nature Communications. 10: 2611. PMID 31197158 DOI: 10.1038/S41467-019-10500-W  0.54
2019 Kreimer A, Yan Z, Ahituv N, Yosef N. Meta-analysis of massively parallel reporter assays enables prediction of regulatory activity. Human Mutation. PMID 31131957 DOI: 10.1002/Humu.23820  0.37
2019 Shigaki D, Adato O, Adhikar AN, Dong S, Hawkins-Hooker A, Inoue F, Juven-Gershon T, Kenlay H, Martin B, Patra A, Penzar DP, Schubach M, Xiong C, Yan Z, Boyle AP, ... ... Yosef N, et al. Integration of Multiple Epigenomic Marks Improves Prediction of Variant Impact in Saturation Mutagenesis Reporter Assay. Human Mutation. PMID 31106481 DOI: 10.1002/Humu.23797  0.386
2019 Chan MM, Smith ZD, Grosswendt S, Kretzmer H, Norman TM, Adamson B, Jost M, Quinn JJ, Yang D, Jones MG, Khodaverdian A, Yosef N, Meissner A, Weissman JS. Molecular recording of mammalian embryogenesis. Nature. PMID 31086336 DOI: 10.1038/S41586-019-1184-5  0.516
2019 Cole MB, Risso D, Wagner A, DeTomaso D, Ngai J, Purdom E, Dudoit S, Yosef N. Performance Assessment and Selection of Normalization Procedures for Single-Cell RNA-Seq. Cell Systems. 8: 315-328.e8. PMID 31022373 DOI: 10.1016/J.Cels.2019.03.010  0.42
2018 Lopez R, Regier J, Cole MB, Jordan MI, Yosef N. Deep generative modeling for single-cell transcriptomics. Nature Methods. 15: 1053-1058. PMID 30504886 DOI: 10.1038/S41592-018-0229-2  0.504
2018 Fischer DS, Theis FJ, Yosef N. Impulse model-based differential expression analysis of time course sequencing data. Nucleic Acids Research. PMID 30102402 DOI: 10.1093/Nar/Gky675  0.371
2018 Street K, Risso D, Fletcher RB, Das D, Ngai J, Yosef N, Purdom E, Dudoit S. Slingshot: cell lineage and pseudotime inference for single-cell transcriptomics. Bmc Genomics. 19: 477. PMID 29914354 DOI: 10.1186/S12864-018-4772-0  0.527
2018 Donnard E, Vangala P, Afik S, McCauley S, Nowosielska A, Kucukural A, Tabak B, Zhu X, Diehl W, McDonel P, Yosef N, Luban J, Garber M. Comparative Analysis of Immune Cells Reveals a Conserved Regulatory Lexicon. Cell Systems. PMID 29454939 DOI: 10.1016/J.Cels.2018.01.002  0.379
2018 Martin-Gayo E, Cole MB, Kolb KE, Ouyang Z, Cronin J, Kazer SW, Ordovas-Montanes J, Lichterfeld M, Walker BD, Yosef N, Shalek AK, Yu XG. A Reproducibility-Based Computational Framework Identifies an Inducible, Enhanced Antiviral State in Dendritic Cells from HIV-1 Elite Controllers. Genome Biology. 19: 10. PMID 29378643 DOI: 10.1186/S13059-017-1385-X  0.404
2017 Regev A, Teichmann SA, Lander ES, Amit I, Benoist C, Birney E, Bodenmiller B, Campbell PJ, Carninci P, Clatworthy M, Clevers H, Deplancke B, Dunham I, Eberwine J, Eils R, ... ... Yosef N, et al. Science Forum: The Human Cell Atlas. Elife. 6. PMID 29206104 DOI: 10.7554/Elife.27041  0.476
2017 Gadye L, Das D, Sanchez MA, Street K, Baudhuin A, Wagner A, Cole MB, Choi YG, Yosef N, Purdom E, Dudoit S, Risso D, Ngai J, Fletcher RB. Injury Activates Transient Olfactory Stem Cell States with Diverse Lineage Capacities. Cell Stem Cell. 21: 775-790.e9. PMID 29174333 DOI: 10.1016/J.Stem.2017.10.014  0.424
2017 Afik S, Yates KB, Bi K, Darko S, Godec J, Gerdemann U, Swadling L, Douek DC, Klenerman P, Barnes EJ, Sharpe AH, Haining WN, Yosef N. Targeted reconstruction of T cell receptor sequence from single cell RNA-seq links CDR3 length to T cell differentiation state. Nucleic Acids Research. 45: e148. PMID 28934479 DOI: 10.1093/Nar/Gkx615  0.512
2017 Ryu AH, Eckalbar WL, Kreimer A, Yosef N, Ahituv N. Use antibiotics in cell culture with caution: genome-wide identification of antibiotic-induced changes in gene expression and regulation. Scientific Reports. 7: 7533. PMID 28790348 DOI: 10.1038/S41598-017-07757-W  0.478
2017 Mertins P, Przybylski D, Yosef N, Qiao J, Clauser K, Raychowdhury R, Eisenhaure TM, Maritzen T, Haucke V, Satoh T, Akira S, Carr SA, Regev A, Hacohen N, Chevrier N. An Integrative Framework Reveals Signaling-to-Transcription Events in Toll-like Receptor Signaling. Cell Reports. 19: 2853-2866. PMID 28658630 DOI: 10.1016/J.Celrep.2017.06.016  0.337
2017 Fletcher RB, Das D, Gadye L, Street KN, Baudhuin A, Wagner A, Cole MB, Flores Q, Choi YG, Yosef N, Purdom E, Dudoit S, Risso D, Ngai J. Deconstructing Olfactory Stem Cell Trajectories at Single-Cell Resolution. Cell Stem Cell. PMID 28506465 DOI: 10.1016/J.Stem.2017.04.003  0.484
2017 Zhang X, Yosef N. A new way to build cell lineages. Elife. 6. PMID 28332977 DOI: 10.7554/Elife.25654  0.483
2017 Kreimer A, Zeng H, Edwards MD, Guo Y, Tian K, Shin S, Welch R, Wainberg M, Mohan R, Sinnott-Armstrong NA, Li Y, Eraslan G, Amin TB, Goke J, Mueller NS, ... ... Yosef N, et al. Predicting gene expression in massively parallel reporter assays: a comparative study. Human Mutation. PMID 28220625 DOI: 10.1002/Humu.23197  0.369
2017 Karwacz K, Miraldi ER, Pokrovskii M, Madi A, Yosef N, Wortman I, Chen X, Watters A, Carriero N, Awasthi A, Regev A, Bonneau R, Littman D, Kuchroo VK. Critical role of IRF1 and BATF in forming chromatin landscape during type 1 regulatory cell differentiation. Nature Immunology. PMID 28166218 DOI: 10.1038/Ni.3683  0.498
2017 Regev A, Teichmann SA, Lander ES, Amit I, Benoist C, Birney E, Bodenmiller B, Campbell P, Carninci P, Clatworthy M, Clevers H, Deplancke B, Dunham I, Eberwine J, Eils R, ... ... Yosef N, et al. Author response: The Human Cell Atlas Elife. DOI: 10.7554/Elife.27041.011  0.38
2016 Yosef N, Regev A. Writ large: Genomic dissection of the effect of cellular environment on immune response. Science (New York, N.Y.). 354: 64-68. PMID 27846493 DOI: 10.1126/Science.Aaf5453  0.427
2016 Wagner A, Regev A, Yosef N. Revealing the vectors of cellular identity with single-cell genomics. Nature Biotechnology. 34: 1145-1160. PMID 27824854 DOI: 10.1038/Nbt.3711  0.562
2016 Sander J, Schultze JL, Yosef N. ImpulseDE: detection of differentially expressed genes in time series data using impulse models. Bioinformatics (Oxford, England). PMID 27797772 DOI: 10.1093/Bioinformatics/Btw665  0.409
2016 Sen DR, Kaminski J, Barnitz RA, Kurachi M, Gerdemann U, Yates KB, Tsao HW, Godec J, LaFleur MW, Brown FD, Tonnerre P, Chung RT, Tully DC, Allen TM, Frahm N, ... ... Yosef N, et al. The epigenetic landscape of T cell exhaustion. Science (New York, N.Y.). PMID 27789799 DOI: 10.1126/science.aae0491  0.312
2016 Ranasinghe S, Lamothe PA, Soghoian DZ, Kazer SW, Cole MB, Shalek AK, Yosef N, Jones RB, Donaghey F, Nwonu C, Jani P, Clayton GM, Crawford F, White J, Montoya A, et al. Antiviral CD8(+) T Cells Restricted by Human Leukocyte Antigen Class II Exist during Natural HIV Infection and Exhibit Clonal Expansion. Immunity. 45: 917-930. PMID 27760342 DOI: 10.1016/J.Immuni.2016.09.015  0.35
2016 Kishi Y, Kondo T, Xiao S, Yosef N, Gaublomme J, Wu C, Wang C, Chihara N, Regev A, Joller N, Kuchroo VK. Protein C receptor (PROCR) is a negative regulator of Th17 pathogenicity. The Journal of Experimental Medicine. PMID 27670590 DOI: 10.1084/Jem.20151118  0.467
2016 DeTomaso D, Yosef N. FastProject: a tool for low-dimensional analysis of single-cell RNA-Seq data. Bmc Bioinformatics. 17: 315. PMID 27553427 DOI: 10.1186/S12859-016-1176-5  0.502
2016 Kohnz RA, Roberts LS, DeTomaso D, Bideyan L, Yan P, Bandyopadhyay S, Goga A, Yosef N, Nomura DK. Protein Sialylation Regulates a Gene Expression Signature that Promotes Breast Cancer Cell Pathogenicity. Acs Chemical Biology. PMID 27380425 DOI: 10.1021/Acschembio.6B00433  0.307
2015 Gaublomme JT, Yosef N, Lee Y, Gertner RS, Yang LV, Wu C, Pandolfi PP, Mak T, Satija R, Shalek AK, Kuchroo VK, Park H, Regev A. Single-Cell Genomics Unveils Critical Regulators of Th17 Cell Pathogenicity. Cell. PMID 26607794 DOI: 10.1016/J.Cell.2015.11.009  0.489
2015 Wang C, Yosef N, Gaublomme J, Wu C, Lee Y, Clish CB, Kaminski J, Xiao S, Zu Horste GM, Pawlak M, Kishi Y, Joller N, Karwacz K, Zhu C, Ordovas-Montanes M, et al. CD5L/AIM Regulates Lipid Biosynthesis and Restrains Th17 Cell Pathogenicity. Cell. PMID 26607793 DOI: 10.1016/J.Cell.2015.10.068  0.461
2015 Shakya A, Goren A, Shalek A, German CN, Snook J, Kuchroo VK, Yosef N, Chan RC, Regev A, Williams MA, Tantin D. Oct1 and OCA-B are selectively required for CD4 memory T cell function. The Journal of Experimental Medicine. PMID 26481684 DOI: 10.1084/Jem.20150363  0.349
2015 Tian R, Wang H, Gish GD, Petsalaki E, Pasculescu A, Shi Y, Mollenauer M, Bagshaw RD, Yosef N, Hunter T, Gingras AC, Weiss A, Pawson T. Combinatorial proteomic analysis of intercellular signaling applied to the CD28 T-cell costimulatory receptor. Proceedings of the National Academy of Sciences of the United States of America. 112: E1594-603. PMID 25829543 DOI: 10.1073/Pnas.1503286112  0.322
2015 Murugaiyan G, da Cunha AP, Ajay AK, Joller N, Garo LP, Kumaradevan S, Yosef N, Vaidya VS, Weiner HL. MicroRNA-21 promotes Th17 differentiation and mediates experimental autoimmune encephalomyelitis. The Journal of Clinical Investigation. 125: 1069-80. PMID 25642768 DOI: 10.1172/Jci74347  0.302
2015 Shakya A, Callister C, Goren A, Yosef N, Garg N, Khoddami V, Nix D, Regev A, Tantin D. Pluripotency transcription factor Oct4 mediates stepwise nucleosome demethylation and depletion. Molecular and Cellular Biology. 35: 1014-25. PMID 25582194 DOI: 10.1128/Mcb.01105-14  0.345
2015 Uziel O, Yosef N, Sharan R, Ruppin E, Kupiec M, Kushnir M, Beery E, Cohen-Diker T, Nordenberg J, Lahav M. The effects of telomere shortening on cancer cells: a network model of proteomic and microRNA analysis. Genomics. 105: 5-16. PMID 25451739 DOI: 10.1016/J.Ygeno.2014.10.013  0.424
2014 Shalek AK, Satija R, Shuga J, Trombetta JJ, Gennert D, Lu D, Chen P, Gertner RS, Gaublomme JT, Yosef N, Schwartz S, Fowler B, Weaver S, Wang J, Wang X, et al. Single-cell RNA-seq reveals dynamic paracrine control of cellular variation. Nature. 510: 363-9. PMID 24919153 DOI: 10.1038/Nature13437  0.59
2014 Xiao S, Yosef N, Yang J, Wang Y, Zhou L, Zhu C, Wu C, Baloglu E, Schmidt D, Ramesh R, Lobera M, Sundrud MS, Tsai PY, Xiang Z, Wang J, et al. Small-molecule RORγt antagonists inhibit T helper 17 cell transcriptional network by divergent mechanisms. Immunity. 40: 477-89. PMID 24745332 DOI: 10.1016/J.Immuni.2014.04.004  0.412
2014 Peters A, Yosef N. Understanding Th17 cells through systematic genomic analyses. Current Opinion in Immunology. 28: 42-8. PMID 24594517 DOI: 10.1016/J.Coi.2014.01.017  0.494
2014 Kurachi M, Barnitz RA, Yosef N, Odorizzi PM, DiIorio MA, Lemieux ME, Yates K, Godec J, Klatt MG, Regev A, Wherry EJ, Haining WN. The transcription factor BATF operates as an essential differentiation checkpoint in early effector CD8+ T cells. Nature Immunology. 15: 373-83. PMID 24584090 DOI: 10.1038/Ni.2834  0.47
2013 Shalek AK, Satija R, Adiconis X, Gertner RS, Gaublomme JT, Raychowdhury R, Schwartz S, Yosef N, Malboeuf C, Lu D, Trombetta JJ, Gennert D, Gnirke A, Goren A, Hacohen N, et al. Single-cell transcriptomics reveals bimodality in expression and splicing in immune cells. Nature. 498: 236-40. PMID 23685454 DOI: 10.1038/Nature12172  0.606
2013 Wu C, Pot C, Apetoh L, Thalhamer T, Zhu B, Murugaiyan G, Xiao S, Lee Y, Rangachari M, Yosef N, Kuchroo VK. Metallothioneins negatively regulate IL-27-induced type 1 regulatory T-cell differentiation. Proceedings of the National Academy of Sciences of the United States of America. 110: 7802-7. PMID 23630250 DOI: 10.1073/Pnas.1211776110  0.33
2013 Kleinewietfeld M, Manzel A, Titze J, Kvakan H, Yosef N, Linker RA, Muller DN, Hafler DA. Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells. Nature. 496: 518-22. PMID 23467095 DOI: 10.1038/Nature11868  0.414
2013 Yosef N, Shalek AK, Gaublomme JT, Jin H, Lee Y, Awasthi A, Wu C, Karwacz K, Xiao S, Jorgolli M, Gennert D, Satija R, Shakya A, Lu DY, Trombetta JJ, et al. Dynamic regulatory network controlling TH17 cell differentiation. Nature. 496: 461-8. PMID 23467089 DOI: 10.1038/Nature11981  0.478
2013 Wu C, Yosef N, Thalhamer T, Zhu C, Xiao S, Kishi Y, Regev A, Kuchroo VK. Induction of pathogenic TH17 cells by inducible salt-sensing kinase SGK1. Nature. 496: 513-7. PMID 23467085 DOI: 10.1038/Nature11984  0.36
2013 Barnitz RA, Kurachi M, Lemieux ME, Yosef N, DiIorio MA, Yates KB, Godec J, Odorizzi P, Regev A, Wherry EJ, Haining WN. The Transcription Factor BATF Controls CD8+ T Cell Effector Differentiation Blood. 122: 189-189. DOI: 10.1182/Blood.V122.21.189.189  0.459
2012 Shalek AK, Gaublomme JT, Wang L, Yosef N, Chevrier N, Andersen MS, Robinson JT, Pochet N, Neuberg D, Gertner RS, Amit I, Brown JR, Hacohen N, Regev A, Wu CJ, et al. Nanowire-mediated delivery enables functional interrogation of primary immune cells: application to the analysis of chronic lymphocytic leukemia. Nano Letters. 12: 6498-504. PMID 23190424 DOI: 10.1021/Nl3042917  0.424
2012 Stein GY, Yosef N, Reichman H, Horev J, Laser-Azogui A, Berens A, Resau J, Ruppin E, Sharan R, Tsarfaty I. Met kinetic signature derived from the response to HGF/SF in a cellular model predicts breast cancer patient survival. Plos One. 7: e45969. PMID 23049908 DOI: 10.1371/Journal.Pone.0045969  0.301
2012 Lee Y, Awasthi A, Yosef N, Quintana FJ, Xiao S, Peters A, Wu C, Kleinewietfeld M, Kunder S, Hafler DA, Sobel RA, Regev A, Kuchroo VK. Induction and molecular signature of pathogenic TH17 cells. Nature Immunology. 13: 991-9. PMID 22961052 DOI: 10.1038/Ni.2416  0.346
2012 Garber M, Yosef N, Goren A, Raychowdhury R, Thielke A, Guttman M, Robinson J, Minie B, Chevrier N, Itzhaki Z, Blecher-Gonen R, Bornstein C, Amann-Zalcenstein D, Weiner A, Friedrich D, et al. A high-throughput chromatin immunoprecipitation approach reveals principles of dynamic gene regulation in mammals. Molecular Cell. 47: 810-22. PMID 22940246 DOI: 10.1016/J.Molcel.2012.07.030  0.376
2011 Ram O, Goren A, Amit I, Shoresh N, Yosef N, Ernst J, Kellis M, Gymrek M, Issner R, Coyne M, Durham T, Zhang X, Donaghey J, Epstein CB, Regev A, et al. Combinatorial patterning of chromatin regulators uncovered by genome-wide location analysis in human cells. Cell. 147: 1628-39. PMID 22196736 DOI: 10.1016/J.Cell.2011.09.057  0.345
2011 Yosef N, Zalckvar E, Rubinstein AD, Homilius M, Atias N, Vardi L, Berman I, Zur H, Kimchi A, Ruppin E, Sharan R. ANAT: a tool for constructing and analyzing functional protein networks. Science Signaling. 4: pl1. PMID 22028466 DOI: 10.1126/Scisignal.2001935  0.31
2011 Yosef N, Regev A. Impulse control: temporal dynamics in gene transcription. Cell. 144: 886-96. PMID 21414481 DOI: 10.1016/J.Cell.2011.02.015  0.348
2011 Novershtern N, Subramanian A, Lawton LN, Mak RH, Haining WN, McConkey ME, Habib N, Yosef N, Chang CY, Shay T, Frampton GM, Drake AC, Leskov I, Nilsson B, Preffer F, et al. Densely interconnected transcriptional circuits control cell states in human hematopoiesis. Cell. 144: 296-309. PMID 21241896 DOI: 10.1016/J.Cell.2011.01.004  0.445
2011 Wang L, Shalek AK, Gaublomme J, Yosef N, Brown JR, Neuberg D, Hacohen N, Park H, Wu CJ. Sensitivity to Wnt Pathway Inhibition in CLL Is Associated with Specific Gene Expression Signatures Blood. 118: 801-801. DOI: 10.1182/Blood.V118.21.801.801  0.47
2010 Levkovitz L, Yosef N, Gershengorn MC, Ruppin E, Sharan R, Oron Y. A novel HMM-based method for detecting enriched transcription factor binding sites reveals RUNX3 as a potential target in pancreatic cancer biology. Plos One. 5: e14423. PMID 21203558 DOI: 10.1371/Journal.Pone.0014423  0.327
2010 Bronstein R, Levkovitz L, Yosef N, Yanku M, Ruppin E, Sharan R, Westphal H, Oliver B, Segal D. Transcriptional regulation by CHIP/LDB complexes. Plos Genetics. 6: e1001063. PMID 20730086 DOI: 10.1371/Journal.Pgen.1001063  0.355
2010 Peleg T, Yosef N, Ruppin E, Sharan R. Network-free inference of knockout effects in yeast. Plos Computational Biology. 6: e1000635. PMID 20066032 DOI: 10.1371/Journal.Pcbi.1000635  0.365
2009 Ungar L, Yosef N, Sela Y, Sharan R, Ruppin E, Kupiec M. A genome-wide screen for essential yeast genes that affect telomere length maintenance. Nucleic Acids Research. 37: 3840-9. PMID 19386622 DOI: 10.1093/Nar/Gkp259  0.339
2009 Yosef N, Ungar L, Zalckvar E, Kimchi A, Kupiec M, Ruppin E, Sharan R. Toward accurate reconstruction of functional protein networks. Molecular Systems Biology. 5: 248. PMID 19293828 DOI: 10.1038/Msb.2009.3  0.344
2007 Yosef N, Yakhini Z, Tsalenko A, Kristensen V, Børresen-Dale AL, Ruppin E, Sharan R. A supervised approach for identifying discriminating genotype patterns and its application to breast cancer data. Bioinformatics (Oxford, England). 23: e91-8. PMID 17237111 DOI: 10.1093/Bioinformatics/Btl298  0.353
2006 Yosef N, Kaufman A, Ruppin E. Inferring functional pathways from multi-perturbation data. Bioinformatics (Oxford, England). 22: e539-46. PMID 16873518 DOI: 10.1093/Bioinformatics/Btl204  0.306
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