Carol H. Sibley - Publications

Affiliations: 
Genome Sciences University of Washington, Seattle, Seattle, WA 
Area:
Genetics, Microbiology Biology
Website:
https://www.gs.washington.edu/faculty/sibley.htm

84 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Sibley CH. A Breakthrough: Defining Plasmodium vivax Drug Resistance Genes. The Journal of Infectious Diseases. PMID 36478038 DOI: 10.1093/infdis/jiac470  0.31
2022 Das S, Kérah-Hinzoumbé C, Kebféné M, Srisutham S, Nagorngar TY, Saralamba N, Vongpromek R, Khomvarn T, Sibley CH, Guérin PJ, Imwong M, Dhorda M. Molecular surveillance for operationally relevant genetic polymorphisms in Plasmodium falciparum in Southern Chad, 2016-2017. Malaria Journal. 21: 83. PMID 35279140 DOI: 10.1186/s12936-022-04095-9  0.307
2020 Mohamed NS, Abdelbagi H, Osman HA, Ahmed AE, Yousif AM, Edris YB, Osman EY, Elsadig AR, Siddig EE, Mustafa M, Mohammed AA, Ali Y, Osman MM, Ali MS, Omer RA, ... ... Sibley CH, et al. A snapshot of Plasmodium falciparum malaria drug resistance markers in Sudan: a pilot study. Bmc Research Notes. 13: 512. PMID 33160417 DOI: 10.1186/s13104-020-05363-0  0.346
2019 Commons RJ, Simpson JA, Thriemer K, Abreha T, Adam I, Anstey NM, Assefa A, Awab GR, Baird JK, Barber BE, Chu CS, Dahal P, Daher A, Davis TME, Dondorp AM, ... ... Sibley CH, et al. The efficacy of dihydroartemisinin-piperaquine and artemether-lumefantrine with and without primaquine on Plasmodium vivax recurrence: A systematic review and individual patient data meta-analysis. Plos Medicine. 16: e1002928. PMID 31584960 DOI: 10.1371/Journal.Pmed.1002928  0.332
2019 Ishengoma DS, Saidi Q, Sibley CH, Roper C, Alifrangis M. Deployment and utilization of next-generation sequencing of Plasmodium falciparum to guide anti-malarial drug policy decisions in sub-Saharan Africa: opportunities and challenges. Malaria Journal. 18: 267. PMID 31477109 DOI: 10.1186/S12936-019-2853-4  0.444
2019 Commons RJ, Simpson JA, Thriemer K, Chu CS, Douglas NM, Abreha T, Alemu SG, Añez A, Anstey NM, Aseffa A, Assefa A, Awab GR, Baird JK, Barber BE, Borghini-Fuhrer I, ... ... Sibley CH, et al. The haematological consequences of Plasmodium vivax malaria after chloroquine treatment with and without primaquine: a WorldWide Antimalarial Resistance Network systematic review and individual patient data meta-analysis. Bmc Medicine. 17: 151. PMID 31366382 DOI: 10.1186/S12916-019-1386-6  0.372
2019 Guerin PJ, Dhorda M, Ganguly NK, Sibley CH. Malaria control in India: A national perspective in a regional and global fight to eliminate malaria. Journal of Vector Borne Diseases. 56: 41-45. PMID 31070164 DOI: 10.4103/0972-9062.257773  0.375
2018 Domingo GJ, Advani N, Satyagraha AW, Sibley CH, Rowley E, Kalnoky M, Cohen J, Parker M, Kelley M. Addressing the gender-knowledge gap in glucose-6-phosphate dehydrogenase deficiency: challenges and opportunities. International Health. PMID 30184203 DOI: 10.1093/Inthealth/Ihy060  0.308
2018 Commons RJ, Simpson JA, Thriemer K, Humphreys GS, Abreha T, Alemu SG, Añez A, Anstey NM, Awab GR, Baird JK, Barber BE, Borghini-Fuhrer I, Chu CS, D'Alessandro U, Dahal P, ... ... Sibley CH, et al. The effect of chloroquine dose and primaquine on Plasmodium vivax recurrence: a WorldWide Antimalarial Resistance Network systematic review and individual patient pooled meta-analysis. The Lancet. Infectious Diseases. PMID 30033231 DOI: 10.1016/S1473-3099(18)30348-7  0.339
2018 Grais RF, Laminou IM, Woi-Messe L, Makarimi R, Bouriema SH, Langendorf C, Amambua-Ngwa A, D'Alessandro U, Guérin PJ, Fandeur T, Sibley CH. Molecular markers of resistance to amodiaquine plus sulfadoxine-pyrimethamine in an area with seasonal malaria chemoprevention in south central Niger. Malaria Journal. 17: 98. PMID 29486766 DOI: 10.1186/S12936-018-2242-4  0.397
2017 Taylor AR, Flegg JA, Holmes CC, Guérin PJ, Sibley CH, Conrad MD, Dorsey G, Rosenthal PJ. Artemether-Lumefantrine and Dihydroartemisinin-Piperaquine Exert Inverse Selective Pressure on Plasmodium Falciparum Drug Sensitivity-Associated Haplotypes in Uganda. Open Forum Infectious Diseases. 4: ofw229. PMID 28480232 DOI: 10.1093/ofid/ofw229  0.325
2016 Grist EP, Flegg JA, Humphreys G, Mas IS, Anderson TJ, Ashley EA, Day NP, Dhorda M, Dondorp AM, Faiz MA, Gething PW, Hien TT, Hlaing TM, Imwong M, Kindermans JM, ... ... Sibley CH, et al. Optimal health and disease management using spatial uncertainty: a geographic characterization of emergent artemisinin-resistant Plasmodium falciparum distributions in Southeast Asia. International Journal of Health Geographics. 15: 37. PMID 27776514 DOI: 10.1186/S12942-016-0064-6  0.347
2015 Dahal P, d'Alessandro U, Dorsey G, Guerin PJ, Nsanzabana C, Price RN, Sibley CH, Stepniewska K, Talisuna AO. Clinical determinants of early parasitological response to ACTs in African patients with uncomplicated falciparum malaria: a literature review and meta-analysis of individual patient data. Bmc Medicine. 13: 212. PMID 26343145 DOI: 10.1186/S12916-015-0445-X  0.373
2015 Sibley CH, Lane KD. Fusion of field studies and the laboratory solves a puzzle in antimalarial resistance. Proceedings of the National Academy of Sciences of the United States of America. 112: 11432-3. PMID 26333834 DOI: 10.1073/Pnas.1514403112  0.36
2015 Sibley CH. Observing in real time the evolution of artemisinin resistance in Plasmodium falciparum. Bmc Medicine. 13: 67. PMID 25889405 DOI: 10.1186/S12916-015-0316-5  0.436
2015 Cohen A, Suzanne P, Lancelot JC, Verhaeghe P, Lesnard A, Basmaciyan L, Hutter S, Laget M, Dumètre A, Paloque L, Deharo E, Crozet MD, Rathelot P, Dallemagne P, Lorthiois A, ... Sibley CH, et al. Discovery of new thienopyrimidinone derivatives displaying antimalarial properties toward both erythrocytic and hepatic stages of Plasmodium. European Journal of Medicinal Chemistry. 95: 16-28. PMID 25791675 DOI: 10.1016/J.Ejmech.2015.03.011  0.352
2015 Sibley CH. Infectious diseases. Understanding artemisinin resistance. Science (New York, N.Y.). 347: 373-4. PMID 25613877 DOI: 10.1126/Science.Aaa4102  0.376
2015 Ashley EA, Aweeka F, Barnes KI, Bassat Q, Borrmann S, Dahal P, Davis TME, Deloron P, Denis MB, Djimde AA, Faucher JF, Genton B, Guérin PJ, Hamed K, Hodel EM, ... ... Sibley CH, et al. Artemether-lumefantrine treatment of uncomplicated Plasmodium falciparum malaria: A systematic review and meta-analysis of day 7 lumefantrine concentrations and therapeutic response using individual patient data Bmc Medicine. 13. DOI: 10.1186/S12916-015-0456-7  0.328
2015 Sibley CH. Artemisinin resistance: The more we know, the more complicated it appears Journal of Infectious Diseases. 211: 667-669. DOI: 10.1093/Infdis/Jiu469  0.342
2014 Venkatesan M, Gadalla NB, Stepniewska K, Dahal P, Nsanzabana C, Moriera C, Price RN, MÃ¥rtensson A, Rosenthal PJ, Dorsey G, Sutherland CJ, Guérin P, Davis TM, Ménard D, Adam I, ... ... Sibley CH, et al. Polymorphisms in Plasmodium falciparum chloroquine resistance transporter and multidrug resistance 1 genes: parasite risk factors that affect treatment outcomes for P. falciparum malaria after artemether-lumefantrine and artesunate-amodiaquine. The American Journal of Tropical Medicine and Hygiene. 91: 833-43. PMID 25048375 DOI: 10.4269/Ajtmh.14-0031  0.336
2014 Sibley CH. Understanding drug resistance in malaria parasites: basic science for public health. Molecular and Biochemical Parasitology. 195: 107-14. PMID 24927641 DOI: 10.1016/J.Molbiopara.2014.06.001  0.36
2014 Lourens C, Lindegardh N, Barnes KI, Guerin PJ, Sibley CH, White NJ, Tarning J. Benefits of a pharmacology antimalarial reference standard and proficiency testing program provided by the Worldwide Antimalarial Resistance Network (WWARN). Antimicrobial Agents and Chemotherapy. 58: 3889-94. PMID 24777099 DOI: 10.1128/Aac.02362-14  0.331
2014 Taylor AR, Flegg JA, Nsobya SL, Yeka A, Kamya MR, Rosenthal PJ, Dorsey G, Sibley CH, Guerin PJ, Holmes CC. Estimation of malaria haplotype and genotype frequencies: a statistical approach to overcome the challenge associated with multiclonal infections. Malaria Journal. 13: 102. PMID 24636676 DOI: 10.1186/1475-2875-13-102  0.446
2013 Sibley CH. Tracking artemisinin resistance in Plasmodium falciparum. The Lancet. Infectious Diseases. 13: 999-1000. PMID 24035557 DOI: 10.1016/S1473-3099(13)70260-3  0.387
2013 Wongsrichanalai C, Sibley CH. Fighting drug-resistant Plasmodium falciparum: the challenge of artemisinin resistance. Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases. 19: 908-16. PMID 24033691 DOI: 10.1111/1469-0691.12316  0.337
2013 Flegg JA, Metcalf CJE, Gharbi M, Venkatesan M, Shewchuk T, Sibley CH, Guerin PJ. Trends in antimalarial drug use in Africa American Journal of Tropical Medicine and Hygiene. 89: 857-865. PMID 24019436 DOI: 10.4269/Ajtmh.13-0129  0.35
2013 Flegg JA, Patil AP, Venkatesan M, Roper C, Naidoo I, Hay SI, Sibley CH, Guerin PJ. Spatiotemporal mathematical modelling of mutations of the dhps gene in African Plasmodium falciparum. Malaria Journal. 12: 249. PMID 23866695 DOI: 10.1186/1475-2875-12-249  0.448
2012 Sibley CH, Price RN. Monitoring antimalarial drug resistance: Applying lessons learned from the past in a fast-moving present. International Journal For Parasitology. Drugs and Drug Resistance. 2: 126-33. PMID 24533274 DOI: 10.1016/j.ijpddr.2012.03.004  0.313
2012 Ako BA, Offianan AT, Johansson M, Penali LK, Assanvo SP, Nguetta, Sibley CH. Molecular analysis of markers associated with chloroquine and sulfadoxine/pyrimethamine resistance in plasmodium falciparum malaria parasites from southeastern côte-d'ivoire by the time of artemisinin-based combination therapy adoption in 2005 Infection and Drug Resistance. 5: 113-120.  0.322
2011 Kögler M, Vanderhoydonck B, De Jonghe S, Rozenski J, Van Belle K, Herman J, Louat T, Parchina A, Sibley C, Lescrinier E, Herdewijn P. Synthesis and evaluation of 5-substituted 2'-deoxyuridine monophosphate analogues as inhibitors of flavin-dependent thymidylate synthase in Mycobacterium tuberculosis. Journal of Medicinal Chemistry. 54: 4847-62. PMID 21657202 DOI: 10.1021/Jm2004688  0.307
2011 Watkins B, Sibley C. Vivax malaria: old drug, new uses? The Journal of Infectious Diseases. 203: 144-5. PMID 21288811 DOI: 10.1093/Infdis/Jiq027  0.451
2010 Lourens C, Watkins WM, Barnes KI, Sibley CH, Guerin PJ, White NJ, Lindegardh N. Implementation of a reference standard and proficiency testing programme by the World Wide Antimalarial Resistance Network (WWARN). Malaria Journal. 9: 375. PMID 21184684 DOI: 10.1186/1475-2875-9-375  0.378
2010 Park M, Cho S, Lee H, Sibley CH, Rhie H. Alternative thymidylate synthase, ThyX, involved in Corynebacterium glutamicum ATCC 13032 survival during stationary growth phase. Fems Microbiology Letters. 307: 128-34. PMID 20636973 DOI: 10.1111/J.1574-6968.2010.01971.X  0.351
2010 Leslie T, Briceño M, Mayan I, Mohammed N, Klinkenberg E, Sibley CH, Whitty CJ, Rowland M. The impact of phenotypic and genotypic G6PD deficiency on risk of plasmodium vivax infection: a case-control study amongst Afghan refugees in Pakistan. Plos Medicine. 7: e1000283. PMID 20520804 DOI: 10.1371/Journal.Pmed.1000283  0.38
2009 Guerin PJ, Bates SJ, Sibley CH. Global resistance surveillance: ensuring antimalarial efficacy in the future. Current Opinion in Infectious Diseases. 22: 593-600. PMID 19797946 DOI: 10.1097/Qco.0B013E328332C4A7  0.399
2009 Hawkins VN, Suzuki SM, Rungsihirunrat K, Hapuarachchi HC, Maestre A, Na-Bangchang K, Sibley CH. Assessment of the origins and spread of putative resistance-conferring mutations in Plasmodium vivax dihydropteroate synthase. The American Journal of Tropical Medicine and Hygiene. 81: 348-55. PMID 19635897 DOI: 10.4269/Ajtmh.2009.81.348  0.499
2008 Ménard D, Andriantsoanirina V, Jahevitra M, Barnadas C, Tichit M, Bouchier C, Sibley CH. Dihydrofolate reductase I164L mutation in Plasmodium falciparum, Madagascar Emerging Infectious Diseases. 14: 1166-1167. PMID 18598653 DOI: 10.3201/Eid1407.071498  0.455
2008 Certain LK, Briceño M, Kiara SM, Nzila AM, Watkins WM, Sibley CH. Characteristics of Plasmodium falciparum dhfr haplotypes that confer pyrimethamine resistance, Kilifi, Kenya, 1987--2006. The Journal of Infectious Diseases. 197: 1743-51. PMID 18513156 DOI: 10.1086/588198  0.745
2008 Hawkins VN, Auliff A, Prajapati SK, Rungsihirunrat K, Hapuarachchi HC, Maestre A, O'Neil MT, Cheng Q, Joshi H, Na-Bangchang K, Sibley CH. Multiple origins of resistance-conferring mutations in Plasmodium vivax dihydrofolate reductase Malaria Journal. 7. PMID 18442404 DOI: 10.1186/1475-2875-7-72  0.459
2008 Rungsihirunrat K, Sibley CH, Mungthin M, Na-Bangchang K. Geographical distribution of amino acid mutations in Plasmodium vivax DHFR and DHPS from malaria endemic areas of Thailand American Journal of Tropical Medicine and Hygiene. 78: 462-467. PMID 18337344 DOI: 10.4269/Ajtmh.2008.78.462  0.474
2008 Ulmer JE, Boum Y, Thouvenel CD, Myllykallio H, Sibley CH. Functional analysis of the Mycobacterium tuberculosis FAD-dependent thymidylate synthase, ThyX, reveals new amino acid residues contributing to an extended ThyX motif. Journal of Bacteriology. 190: 2056-64. PMID 18192395 DOI: 10.1128/Jb.01094-07  0.768
2008 Sibley CH, Barnes KI, Watkins WM, Plowe CV. A network to monitor antimalarial drug resistance: a plan for moving forward. Trends in Parasitology. 24: 43-8. PMID 18042432 DOI: 10.1016/J.Pt.2007.09.008  0.404
2007 Barnes KI, Lindegardh N, Ogundahunsi O, Olliaro P, Plowe CV, Randrianarivelojosia M, Gbotosho GO, Watkins WM, Sibley CH, White NJ. World Antimalarial Resistance Network (WARN) IV: clinical pharmacology. Malaria Journal. 6: 122. PMID 17822537 DOI: 10.1186/1475-2875-6-122  0.42
2007 Plowe CV, Roper C, Barnwell JW, Happi CT, Joshi HH, Mbacham W, Meshnick SR, Mugittu K, Naidoo I, Price RN, Shafer RW, Sibley CH, Sutherland CJ, Zimmerman PA, Rosenthal PJ. World Antimalarial Resistance Network (WARN) III: molecular markers for drug resistant malaria. Malaria Journal. 6: 121. PMID 17822535 DOI: 10.1186/1475-2875-6-121  0.446
2007 Bacon DJ, Jambou R, Fandeur T, Le Bras J, Wongsrichanalai C, Fukuda MM, Ringwald P, Sibley CH, Kyle DE. World Antimalarial Resistance Network (WARN) II: in vitro antimalarial drug susceptibility. Malaria Journal. 6: 120. PMID 17822533 DOI: 10.1186/1475-2875-6-120  0.446
2007 Price RN, Dorsey G, Ashley EA, Barnes KI, Baird JK, d'Alessandro U, Guerin PJ, Laufer MK, Naidoo I, Nosten F, Olliaro P, Plowe CV, Ringwald P, Sibley CH, Stepniewska K, et al. World Antimalarial Resistance Network I: clinical efficacy of antimalarial drugs. Malaria Journal. 6: 119. PMID 17822532 DOI: 10.1186/1475-2875-6-119  0.308
2007 Sibley CH, Barnes KI, Plowe CV. The rationale and plan for creating a World Antimalarial Resistance Network (WARN). Malaria Journal. 6: 118. PMID 17822531 DOI: 10.1186/1475-2875-6-118  0.417
2007 Rungsihirunrat K, Na-Bangchang K, Hawkins VN, Mungthin M, Sibley CH. Sensitivity to antifolates and genetic analysis of Plasmodium vivax isolates from Thailand American Journal of Tropical Medicine and Hygiene. 76: 1057-1065. PMID 17556611 DOI: 10.4269/Ajtmh.2007.76.1057  0.378
2007 Sandefur CI, Wooden JM, Quaye IK, Sirawaraporn W, Sibley CH. Pyrimethamine-resistant dihydrofolate reductase enzymes of Plasmodium falciparum are not enzymatically compromised in vitro Molecular and Biochemical Parasitology. 154: 1-5. PMID 17451822 DOI: 10.1016/J.Molbiopara.2007.03.009  0.49
2007 Hawkins VN, Joshi H, Rungsihirunrat K, Na-Bangchang K, Sibley CH. Antifolates can have a role in the treatment of Plasmodium vivax Trends in Parasitology. 23: 213-222. PMID 17368986 DOI: 10.1016/J.Pt.2007.03.002  0.419
2007 Certain LK, Sibley CH. Plasmodium falciparum: a novel method for analyzing haplotypes in mixed infections. Experimental Parasitology. 115: 233-41. PMID 17049516 DOI: 10.1016/J.Exppara.2006.09.003  0.73
2006 Sampathkumar P, Turley S, Sibley CH, Hol WG. NADP+ expels both the co-factor and a substrate analog from the Mycobacterium tuberculosis ThyX active site: opportunities for anti-bacterial drug design. Journal of Molecular Biology. 360: 1-6. PMID 16730023 DOI: 10.1016/J.Jmb.2006.04.061  0.324
2006 Hapuarachchi HC, Dayanath MY, Bandara KB, Abeysundara S, Abeyewickreme W, de Silva NR, Hunt SY, Sibley CH. Point mutations in the dihydrofolate reductase and dihydropteroate synthase genes of Plasmodium falciparum and resistance to sulfadoxine-pyrimethamine in Sri Lanka. The American Journal of Tropical Medicine and Hygiene. 74: 198-204. PMID 16474070 DOI: 10.4269/Ajtmh.2006.74.198  0.483
2005 Hunt SY, Detering C, Varani G, Jacobus DP, Schiehser GA, Shieh HM, Nevchas I, Terpinski J, Sibley CH. Identification of the optimal third generation antifolate against P. falciparum and P. vivax. Molecular and Biochemical Parasitology. 144: 198-205. PMID 16181688 DOI: 10.1016/J.Molbiopara.2005.08.014  0.307
2005 Sampathkumar P, Turley S, Ulmer JE, Rhie HG, Sibley CH, Hol WG. Structure of the Mycobacterium tuberculosis flavin dependent thymidylate synthase (MtbThyX) at 2.0A resolution. Journal of Molecular Biology. 352: 1091-104. PMID 16139296 DOI: 10.1016/J.Jmb.2005.07.071  0.762
2005 Watkins WM, Sibley CH, Hastings IM. The search for effective and sustainable treatments for Plasmodium falciparum malaria in Africa: A model of the selection of resistance by antifolate drugs and their combinations American Journal of Tropical Medicine and Hygiene. 72: 163-173. PMID 15741553 DOI: 10.4269/Ajtmh.2005.72.163  0.405
2005 Hastings MD, Maguire JD, Bangs MJ, Zimmerman PA, Reeder JC, Baird JK, Sibley CH. Novel Plasmodium vivax dhfr alleles from the Indonesian Archipelago and Papua New Guinea: association with pyrimethamine resistance determined by a Saccharomyces cerevisiae expression system. Antimicrobial Agents and Chemotherapy. 49: 733-40. PMID 15673758 DOI: 10.1128/Aac.49.2.733-740.2005  0.789
2005 Hunt SY, Rezvani BB, Sibley CH. Novel alleles of Plasmodium falciparum dhfr that confer resistance to chlorcycloguanil. Molecular and Biochemical Parasitology. 139: 25-32. PMID 15610816 DOI: 10.1016/J.Molbiopara.2004.09.005  0.345
2004 Bates SJ, Winstanley PA, Watkins WM, Alloueche A, Bwika J, Happi TC, Kremsner PG, Kublin JG, Premji Z, Sibley CH. Rare, highly pyrimethamine-resistant alleles of the Plasmodium falciparum dihydrofolate reductase gene from 5 African sites Journal of Infectious Diseases. 190: 1783-1792. PMID 15499534 DOI: 10.1086/425078  0.48
2004 Rosowsky A, Forsch RA, Sibley CH, Inderlied CB, Queener SF. New 2,4-diamino-5-(2',5'-substituted benzyl)pyrimidines as potential drugs against opportunistic infections of AIDS and other immune disorders. Synthesis and species-dependent antifolate activity. Journal of Medicinal Chemistry. 47: 1475-86. PMID 14998335 DOI: 10.1021/Jm030438K  0.303
2004 Hastings MD, Porter KM, Maguire JD, Susanti I, Kania W, Bangs MJ, Sibley CH, Baird JK. Dihydrofolate reductase mutations in Plasmodium vivax from Indonesia and therapeutic response to sulfadoxine plus pyrimethamine. The Journal of Infectious Diseases. 189: 744-50. PMID 14767830 DOI: 10.1086/381397  0.777
2002 Hastings MD, Bates SJ, Blackstone EA, Monks SM, Mutabingwa TK, Sibley CH. Highly pyrimethamine-resistant alleles of dihydrofolate reductase in isolates of Plasmodium falciparum from Tanzania. Transactions of the Royal Society of Tropical Medicine and Hygiene. 96: 674-6. PMID 12630380 DOI: 10.1016/S0035-9203(02)90349-4  0.771
2002 Nzila AM, Mberu EK, Nduati E, Ross A, Watkins WM, Sibley CH. Genetic diversity of Plasmodium falciparum parasites from Kenya is not affected by antifolate drug selection International Journal For Parasitology. 32: 1469-1476. PMID 12392912 DOI: 10.1016/S0020-7519(02)00164-9  0.404
2002 Gerum AB, Ulmer JE, Jacobus DP, Jensen NP, Sherman DR, Sibley CH. Novel Saccharomyces cerevisiae screen identifies WR99210 analogues that inhibit Mycobacterium tuberculosis dihydrofolate reductase. Antimicrobial Agents and Chemotherapy. 46: 3362-9. PMID 12384337 DOI: 10.1128/Aac.46.11.3362-3369.2002  0.773
2002 Hastings MD, Sibley CH. Pyrimethamine and WR99210 exert opposing selection on dihydrofolate reductase from Plasmodium vivax. Proceedings of the National Academy of Sciences of the United States of America. 99: 13137-41. PMID 12198181 DOI: 10.1073/Pnas.182295999  0.796
2002 Watkins WM, Winstanley PA, Sibley CH. Pyrimethamine–sulfadoxine resistance in Plasmodium falciparum must be delayed in Africa Trends in Parasitology. 18: 294. DOI: 10.1016/S1471-4922(02)02295-X  0.423
2001 Sibley CH, Macreadie I. Novel approaches to tackling malarial drug resistance using yeast Iubmb Life. 52. PMID 11895077 DOI: 10.1080/152165401317291138  0.449
2001 Hankins EG, Warhurst DC, Sibley CH. Novel alleles of the Plasmodium falciparum dhfr highly resistant to pyrimethamine and chlorcycloguanil, but not WR99210. Molecular and Biochemical Parasitology. 117: 91-102. PMID 11551635 DOI: 10.1016/S0166-6851(01)00335-8  0.764
2001 Ferlan JT, Mookherjee S, Okezie IN, Fulgence L, Sibley CH. Mutagenesis of dihydrofolate reductase from Plasmodium falciparum: analysis in Saccharomyces cerevisiae of triple mutant alleles resistant to pyrimethamine or WR99210. Molecular and Biochemical Parasitology. 113: 139-50. PMID 11254962 DOI: 10.1016/S0166-6851(01)00207-9  0.497
2001 Lau H, Ferlan JT, Brophy VH, Rosowsky A, Sibley CH. Efficacies of lipophilic inhibitors of dihydrofolate reductase against parasitic protozoa Antimicrobial Agents and Chemotherapy. 45: 187-195. PMID 11120964 DOI: 10.1128/AAC.45.1.187-195.2001  0.33
2001 Macreadie I, Sibley CH. Yeast enlists in the light against malaria Today's Life Science. 13: 46-50.  0.301
2000 Mberu EK, Mosobo MK, Nzila AM, Kokwaro GO, Sibley CH, Watkins WM. The changing in vitro susceptibility pattern to pyrimethamine/ sulfadoxine in Plasmodium falciparum field isolates from Kilifi, Kenya American Journal of Tropical Medicine and Hygiene. 62: 396-401. PMID 11037785 DOI: 10.4269/Ajtmh.2000.62.396  0.385
2000 Nzila AM, Nduati E, Mberu EK, Sibley CH, Monks SA, Winstanley PA, Watkins WM. Molecular evidence of greater selective pressure for drug resistance exerted by the long-acting antifolate pyrimethamine/sulfadoxine compared with the shorter-acting chlorproguanil/dapsone on Kenyan Plasmodium falciparum Journal of Infectious Diseases. 181: 2023-2028. PMID 10837185 DOI: 10.1086/315520  0.451
2000 Nzila AM, Mberu EK, Sulo J, Dayo H, Winstanley PA, Sibley CH, Watkins WM. Towards an understanding of the mechanism of pyrimethamine-sulfadoxine resistance in Plasmodium falciparum: Genotyping of dihydrofolate reductase and dihydropteroate synthase of Kenyan parasites Antimicrobial Agents and Chemotherapy. 44: 991-996. PMID 10722502 DOI: 10.1128/Aac.44.4.991-996.2000  0.456
1999 Mookherjee S, Howard V, Nzila-Mouanda A, Watkins W, Sibley CH. Identification and analysis of dihydrofolate reductase alleles from Plasmodium falciparum present at low frequency in polyclonal patient samples. The American Journal of Tropical Medicine and Hygiene. 61: 131-40. PMID 10432070  0.382
1997 Sibley CH, Brophy VH, Cheesman S, Hamilton KL, Hankins EG, Wooden JM, Kilbey B. Yeast as a model system to study drugs effective against apicomplexan proteins. Methods (San Diego, Calif.). 13: 190-207. PMID 9405202 DOI: 10.1006/Meth.1997.0511  0.752
1997 Wooden JM, Hartwell LH, Vasquez B, Sibley CH. Analysis in yeast of antimalaria drugs that target the dihydrofolate reductase of Plasmodium falciparum. Molecular and Biochemical Parasitology. 85: 25-40. PMID 9108546 DOI: 10.1016/S0166-6851(96)02808-3  0.515
1992 Wooden J, Gould EE, Paull AT, Sibley CH. Plasmodium falciparum: A simple polymerase chain reaction method for differentiating strains Experimental Parasitology. 75: 207-212. PMID 1516668 DOI: 10.1016/0014-4894(92)90180-I  0.346
1986 Irick HA, Andrews RW, Yang IH, Blanton RA, Sibley CH. Molecular analysis of membrane immunoglobulin-negative variants Immunogenetics. 24: 8-16. PMID 3488271 DOI: 10.1007/Bf00372292  0.308
1979 Sibley CH, Yamamoto KR. Mouse lymphoma cells: mechanisms of resistance to glucocorticoids Monographs On Endocrinology. 12: 357-376. PMID 492175  0.532
1976 Yamamoto KR, Gehring U, Stampfer MR, Sibley CH. Genetic approaches to steroid hormone action Recent Progress in Hormone Research. 32: 3-32. PMID 183244  0.438
1974 Sibley CH, Tomkins GM. Isolation of lymphoma cell variants resistant to killing by glucocorticoids. Cell. 2: 213-20. PMID 4472165 DOI: 10.1016/0092-8674(74)90013-0  0.536
1974 Sibley CH, Tomkins GM. Mechanisms of steroid resistance. Cell. 2: 221-7. PMID 4370191 DOI: 10.1016/0092-8674(74)90014-2  0.496
1973 Santi DV, Sibley CH, Perriard ER, Tomkins GM, Baxter JD. A filter assay for steroid hormone receptors. Biochemistry. 12: 2412-6. PMID 4350952 DOI: 10.1021/Bi00737A007  0.56
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