| Year |
Citation |
Score |
| 2018 |
Yang WH, Heithoff DM, Aziz PV, Haslund-Gourley B, Westman JS, Narisawa S, Pinkerton AB, Millán JL, Nizet V, Mahan MJ, Marth JD. Accelerated Aging and Clearance of Host Anti-inflammatory Enzymes by Discrete Pathogens Fuels Sepsis. Cell Host & Microbe. 24: 500-513.e5. PMID 30308156 DOI: 10.1016/J.Chom.2018.09.011 |
0.446 |
|
| 2017 |
Yang WH, Heithoff DM, Aziz PV, Sperandio M, Nizet V, Mahan MJ, Marth JD. Recurrent infection progressively disables host protection against intestinal inflammation. Science (New York, N.Y.). 358. PMID 29269445 DOI: 10.1126/Science.Aao5610 |
0.393 |
|
| 2017 |
Ersoy SC, Heithoff DM, Barnes L, Tripp GK, House JK, Marth JD, Smith JW, Mahan MJ. Correcting a Fundamental Flaw in the Paradigm for Antimicrobial Susceptibility Testing. Ebiomedicine. PMID 28579300 DOI: 10.1016/J.Ebiom.2017.05.026 |
0.433 |
|
| 2015 |
Kubicek-Sutherland JZ, Heithoff DM, Ersoy SC, Shimp WR, House JK, Marth JD, Smith JW, Mahan MJ. Host-dependent Induction of Transient Antibiotic Resistance: A Prelude to Treatment Failure. Ebiomedicine. 2: 1169-78. PMID 26501114 DOI: 10.1016/J.Ebiom.2015.08.012 |
0.77 |
|
| 2015 |
Heithoff DM, Mahan MJ. Pandemic influenza virus: tracking a three-headed monster. Virulence. 6: 405-6. PMID 25738965 DOI: 10.1080/21505594.2015.1020275 |
0.365 |
|
| 2015 |
Heithoff DM, House JK, Thomson PC, Mahan MJ. Development of a Salmonella cross-protective vaccine for food animal production systems. Vaccine. 33: 100-7. PMID 25448106 DOI: 10.1016/J.Vaccine.2014.11.012 |
0.431 |
|
| 2014 |
Kubicek-Sutherland JZ, Heithoff DM, Ersoy SC, Shimp WR, Mahan MJ. Immunization with a DNA adenine methylase over-producing Yersinia pseudotuberculosis vaccine confers robust cross-protection against heterologous pathogenic serotypes. Vaccine. 32: 1451-9. PMID 24508035 DOI: 10.1016/J.Vaccine.2014.01.036 |
0.806 |
|
| 2013 |
Patterson AS, Heithoff DM, Ferguson BS, Soh HT, Mahan MJ, Plaxco KW. Microfluidic chip-based detection and intraspecies strain discrimination of Salmonella serovars derived from whole blood of septic mice. Applied and Environmental Microbiology. 79: 2302-11. PMID 23354710 DOI: 10.1128/Aem.03882-12 |
0.422 |
|
| 2013 |
Mahan MJ, Kubicek-Sutherland JZ, Heithoff DM. Rise of the microbes. Virulence. 4: 213-22. PMID 23334178 DOI: 10.4161/Viru.23380 |
0.378 |
|
| 2012 |
Mahan MJ, Heithoff DM, House JK. Salmonella cross-protective vaccines: fast-forward to the next generation of food safety. Future Microbiology. 7: 805-8. PMID 22827301 DOI: 10.2217/Fmb.12.60 |
0.302 |
|
| 2012 |
Heithoff DM, Shimp WR, House JK, Xie Y, Weimer BC, Sinsheimer RL, Mahan MJ. Intraspecies variation in the emergence of hyperinfectious bacterial strains in nature. Plos Pathogens. 8: e1002647. PMID 22511871 DOI: 10.1371/Journal.Ppat.1002647 |
0.807 |
|
| 2012 |
Mohler VL, Heithoff DM, Mahan MJ, Hornitzky MA, Thomson PC, House JK. Development of a novel in-water vaccination protocol for DNA adenine methylase deficient Salmonella enterica serovar Typhimurium vaccine in adult sheep Vaccine. 30: 1481-1491. PMID 22214887 DOI: 10.1016/J.Vaccine.2011.12.079 |
0.368 |
|
| 2011 |
Mohler VL, Heithoff DM, Mahan MJ, Walker KH, Hornitzky MA, Gabor L, Thomson PC, Thompson A, House JK. Protective immunity conferred by a DNA adenine methylase deficient Salmonella enterica serovar Typhimurium vaccine when delivered in-water to sheep challenged with Salmonella enterica serovar Typhimurium. Vaccine. 29: 3571-82. PMID 21473951 DOI: 10.1016/J.Vaccine.2011.03.075 |
0.445 |
|
| 2008 |
Heithoff DM, Enioutina EY, Bareyan D, Daynes RA, Mahan MJ. Conditions that diminish myeloid-derived suppressor cell activities stimulate cross-protective immunity. Infection and Immunity. 76: 5191-9. PMID 18765736 DOI: 10.1128/Iai.00759-08 |
0.497 |
|
| 2008 |
Mohler VL, Heithoff DM, Mahan MJ, Walker KH, Hornitzky MA, Shum LWC, Makin KJ, House JK. Cross-protective immunity conferred by a DNA adenine methylase deficient Salmonella enterica serovar Typhimurium vaccine in calves challenged with Salmonella serovar Newport Vaccine. 26: 1751-1758. PMID 18329764 DOI: 10.1016/J.Vaccine.2008.01.018 |
0.476 |
|
| 2008 |
Heithoff DM, Shimp WR, Lau PW, Badie G, Enioutina EY, Daynes RA, Byrne BA, House JK, Mahan MJ. Human Salmonella clinical isolates distinct from those of animal origin. Applied and Environmental Microbiology. 74: 1757-66. PMID 18245251 DOI: 10.1128/Aem.02740-07 |
0.725 |
|
| 2007 |
Simon R, Heithoff DM, Mahan MJ, Samuel CE. Comparison of tissue-selective proinflammatory gene induction in mice infected with wild-type, DNA adenine methylase-deficient, and flagellin-deficient Salmonella enterica. Infection and Immunity. 75: 5627-39. PMID 17893133 DOI: 10.1128/Iai.01021-07 |
0.521 |
|
| 2007 |
Heithoff DM, Badie G, Julio SM, Enioutina EY, Daynes RA, Sinsheimer RL, Mahan MJ. In vivo-selected mutations in methyl-directed mismatch repair suppress the virulence attenuation of Salmonella dam mutant strains following intraperitoneal, but not oral, infection of naïve mice. Journal of Bacteriology. 189: 4708-17. PMID 17468250 DOI: 10.1128/Jb.00299-07 |
0.742 |
|
| 2007 |
Badie G, Heithoff DM, Sinsheimer RL, Mahan MJ. Altered levels of Salmonella DNA adenine methylase are associated with defects in gene expression, motility, flagellar synthesis, and bile resistance in the pathogenic strain 14028 but not in the laboratory strain LT2. Journal of Bacteriology. 189: 1556-64. PMID 17172341 DOI: 10.1128/Jb.01580-06 |
0.788 |
|
| 2006 |
Mohler VL, Heithoff DM, Mahan MJ, Walker KH, Hornitzky MA, McConnell CS, Shum LW, House JK. Cross-protective immunity in calves conferred by a DNA adenine methylase deficient Salmonellaenterica serovar Typhimurium vaccine. Vaccine. 24: 1339-45. PMID 16300866 DOI: 10.1016/J.Vaccine.2005.09.022 |
0.465 |
|
| 2004 |
Badie G, Heithoff DM, Mahan MJ. LcrV synthesis is altered by DNA adenine methylase overproduction in Yersinia pseudotuberculosis and is required to confer immunity in vaccinated hosts. Infection and Immunity. 72: 6707-10. PMID 15501808 DOI: 10.1128/Iai.72.11.6707-6710.2004 |
0.761 |
|
| 2004 |
Heithoff DM, Mahan MJ. Vibrio cholerae biofilms: stuck between a rock and a hard place. Journal of Bacteriology. 186: 4835-7. PMID 15262913 DOI: 10.1128/Jb.186.15.4835-4837.2004 |
0.349 |
|
| 2003 |
Dueger EL, House JK, Heithoff DM, Mahan MJ. Salmonella DNA adenine methylase mutants elicit early and late onset protective immune responses in calves Vaccine. 21: 3249-3258. PMID 12804855 DOI: 10.1016/S0264-410X(03)00252-4 |
0.465 |
|
| 2003 |
Dueger EL, House JK, Heithoff DM, Mahan MJ. Salmonella DNA adenine methylase mutants prevent colonization of newly hatched chickens by homologous and heterologous serovars International Journal of Food Microbiology. 80: 153-159. PMID 12381401 DOI: 10.1016/S0168-1605(02)00152-6 |
0.505 |
|
| 2002 |
Shtrichman R, Heithoff DM, Mahan MJ, Samuel CE. Tissue selectivity of interferon-stimulated gene expression in mice infected with Dam(+) versus Dam(-) Salmonella enterica serovar Typhimurium strains. Infection and Immunity. 70: 5579-88. PMID 12228285 DOI: 10.1128/Iai.70.10.5579-5588.2002 |
0.453 |
|
| 2002 |
Julio SM, Heithoff DM, Sinsheimer RL, Low DA, Mahan MJ. DNA adenine methylase overproduction in Yersinia pseudotuberculosis alters YopE expression and secretion and host immune responses to infection. Infection and Immunity. 70: 1006-9. PMID 11796641 DOI: 10.1128/Iai.70.2.1006-1009.2002 |
0.806 |
|
| 2001 |
Dueger EL, House JK, Heithoff DM, Mahan MJ. Salmonella DNA adenine methylase mutants elicit protective immune responses to homologous and heterologous serovars in chickens Infection and Immunity. 69: 7950-7954. PMID 11705984 DOI: 10.1128/Iai.69.12.7950-7954.2001 |
0.503 |
|
| 2001 |
Julio SM, Heithoff DM, Provenzano D, Klose KE, Sinsheimer RL, Low DA, Mahan MJ. DNA adenine methylase is essential for viability and plays a role in the pathogenesis of Yersinia pseudotuberculosis and Vibrio cholerae. Infection and Immunity. 69: 7610-5. PMID 11705940 DOI: 10.1128/Iai.69.12.7610-7615.2001 |
0.815 |
|
| 2001 |
Low DA, Weyand NJ, Mahan MJ. Roles of DNA adenine methylation in regulating bacterial gene expression and virulence Infection and Immunity. 69: 7197-7204. PMID 11705888 DOI: 10.1128/Iai.69.12.7197-7204.2001 |
0.333 |
|
| 2001 |
Heithoff DM, Enioutina EY, Daynes RA, Sinsheimer RL, Low DA, Mahan MJ. Salmonella DNA adenine methylase mutants confer cross-protective immunity. Infection and Immunity. 69: 6725-30. PMID 11598044 DOI: 10.1128/Iai.69.11.6725-6730.2001 |
0.54 |
|
| 2001 |
Low DA, Mahan MJ. Editorial overview: Techniques hosting an infection: The complex interplay between microbes and their hosts Current Opinion in Microbiology. 4: 235-236. DOI: 10.1016/S1369-5274(00)00196-X |
0.36 |
|
| 2000 |
Mahan MJ, Heithoff DM, Sinsheimer RL, Low DA. Assessment of bacterial pathogenesis by analysis of gene expression in the host. Annual Review of Genetics. 34: 139-164. PMID 11092824 DOI: 10.1146/Annurev.Genet.34.1.139 |
0.488 |
|
| 2000 |
Heithoff DM, Sinsheimer RL, Low DA, Mahan MJ. In vivo gene expression and the adaptive response: from pathogenesis to vaccines and antimicrobials. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 355: 633-42. PMID 10874736 DOI: 10.1098/Rstb.2000.0604 |
0.531 |
|
| 2000 |
Handfield M, Lehoux DE, Sanschagrin F, Mahan MJ, Woods DE, Levesque RC. In vivo-induced genes in Pseudomonas aeruginosa. Infection and Immunity. 68: 2359-62. PMID 10722644 DOI: 10.1128/Iai.68.4.2359-2362.2000 |
0.357 |
|
| 2000 |
Julio SM, Heithoff DM, Mahan MJ. ssrA (tmRNA) plays a role in Salmonella enterica serovar Typhimurium pathogenesis. Journal of Bacteriology. 182: 1558-63. PMID 10692360 DOI: 10.1128/Jb.182.6.1558-1563.2000 |
0.785 |
|
| 1999 |
Heithoff DM, Sinsheimer RL, Low DA, Mahan MJ. An essential role for DNA adenine methylation in bacterial virulence. Science (New York, N.Y.). 284: 967-70. PMID 10320378 DOI: 10.1126/Science.284.5416.967 |
0.474 |
|
| 1999 |
Heithoff DM, Conner CP, Hentschel U, Govantes F, Hanna PC, Mahan MJ. Coordinate intracellular expression of Salmonella genes induced during infection Journal of Bacteriology. 181: 799-807. PMID 9922242 DOI: 10.1128/Jb.181.3.799-807.1999 |
0.38 |
|
| 1998 |
Julio SM, Conner CP, Heithoff DM, Mahan MJ. Directed formation of chromosomal deletions in Salmonella typhimurium: targeting of specific genes induced during infection. Molecular & General Genetics : Mgg. 258: 178-81. PMID 9613587 DOI: 10.1007/S004380050721 |
0.779 |
|
| 1998 |
Conner CP, Heithoff DM, Julio SM, Sinsheimer RL, Mahan MJ. Differential patterns of acquired virulence genes distinguish Salmonella strains. Proceedings of the National Academy of Sciences of the United States of America. 95: 4641-5. PMID 9539791 DOI: 10.1073/Pnas.95.8.4641 |
0.8 |
|
| 1997 |
Heithoff DM, Conner CP, Mahan MJ. Dissecting the biology of a pathogen during infection Trends in Microbiology. 5: 509-512. PMID 9447664 DOI: 10.1016/S0966-842X(97)01153-0 |
0.471 |
|
| 1997 |
Conner CP, Heithoff DM, Mahan MJ. In vivo gene expression: Contributions to infection, virulence, and pathogenesis Current Topics in Microbiology and Immunology. 225: 1-12. PMID 9386325 DOI: 10.1007/978-3-642-80451-9_1 |
0.504 |
|
| 1997 |
Rainey PB, Heithoff DM, Mahan MJ. Single-step conjugative cloning of bacterial gene fusions involved in microbe-host interactions. Molecular & General Genetics : Mgg. 256: 84-7. PMID 9341682 DOI: 10.1007/S004380050548 |
0.41 |
|
| 1997 |
Heithoff DM, Conner CP, Hanna PC, Julio SM, Hentschel U, Mahan MJ. Bacterial infection as assessed by in vivo gene expression. Proceedings of the National Academy of Sciences of the United States of America. 94: 934-9. PMID 9023360 DOI: 10.1073/Pnas.94.3.934 |
0.793 |
|
| 1996 |
Slauch JM, Lee AA, Mahan MJ, Mekalanos JJ. Molecular characterization of the oafA locus responsible for acetylation of Salmonella typhimurium O-antigen: OafA is a member of a family of integral membrane trans-acylases Journal of Bacteriology. 178: 5904-5909. PMID 8830685 DOI: 10.1128/Jb.178.20.5904-5909.1996 |
0.364 |
|
| 1996 |
Garzón A, Beuzón CR, Mahan MJ, Casadesús J. recB recJ mutants of Salmonella typhimurium are deficient in transductional recombination, DNA repair and plasmid maintenance Molecular and General Genetics. 250: 570-580. PMID 8676860 DOI: 10.1007/Bf02174445 |
0.435 |
|
| 1995 |
Mahan MJ, Tobias JW, Slauch JM, Hanna PC, Collier RJ, Mekalanos JJ. Antibiotic-based selection for bacterial genes that are specifically induced during infection of a host. Proceedings of the National Academy of Sciences of the United States of America. 92: 669-73. PMID 7846034 DOI: 10.1073/Pnas.92.3.669 |
0.405 |
|
| 1994 |
Slauch JM, Mahan MJ, Mekalanos JJ. In vivo expression technology for selection of bacterial genes specifically induced in host tissues Methods in Enzymology. 235: 481-492. PMID 8057920 DOI: 10.1016/0076-6879(94)35164-3 |
0.394 |
|
| 1994 |
Slauch JM, Mahan MJ, Mekalanos JJ. Measurement of transcriptional activity in pathogenic bacteria recovered directly from infected host tissue Biotechniques. 16: 641-642+644. PMID 8024783 |
0.373 |
|
| 1993 |
Mahan MJ, Slauch JM, Mekalanos JJ. Selection of bacterial virulence genes that are specifically induced in host tissues Science. 259: 686-688. PMID 8430319 DOI: 10.1126/Science.8430319 |
0.412 |
|
| 1993 |
Mahan MJ, Slauch JM, Hanna PC, Camilli A, Tobias JW, Waldor MK, Mekalanos JJ. Selection for bacterial genes that are specifically induced in host tissues: The hunt for virulence factors Infectious Agents and Disease. 2: 263-268. PMID 8173806 |
0.363 |
|
| 1992 |
Mahan MJ, Casadesus J, Roth JR. The Salmonella typbimurium RecJ function permits growth of P22 abc phage on recBCD+ hosts Mgg Molecular &Amp; General Genetics. 232: 470-478. PMID 1588916 DOI: 10.1007/Bf00266252 |
0.365 |
|
| 1992 |
Michetti P, Mahan MJ, Slauch JM, Mekalanos JJ, Neutra MR. Monoclonal secretory immunoglobulin A protects mice against oral challenge with the invasive pathogen Salmonella typhimurium Infection and Immunity. 60: 1786-1792. PMID 1373399 DOI: 10.1128/Iai.60.5.1786-1792.1992 |
0.309 |
|
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