| Year |
Citation |
Score |
| 2023 |
Schou M, Amini N, Takano A, Arakawa R, Dahl K, Toth M, Svedberg M, Varrone A, Halldin C. Microsome Mediated in Vitro Metabolism: A Convenient Method for the Preparation of the PET Radioligand Metabolite [F]FE-PE2I-OH for Translational Dopamine Transporter Imaging. Acs Chemical Neuroscience. 14: 3732-3736. PMID 37753876 DOI: 10.1021/acschemneuro.3c00458 |
0.372 |
|
| 2023 |
Jonasson M, Frick A, Fazio P, Hjorth O, Danfors T, Axelsson J, Appel L, Furmark T, Varrone A, Lubberink M. Striatal dopamine transporter and receptor availability correlate with relative cerebral blood flow measured with [C]PE2I, [F]FE-PE2I and [C]raclopride PET in healthy individuals. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X231160881. PMID 36912083 DOI: 10.1177/0271678X231160881 |
0.304 |
|
| 2023 |
Kerstens VS, Fazio P, Sundgren M, Brumberg J, Halldin C, Svenningsson P, Varrone A. Longitudinal DAT changes measured with [F]FE-PE2I PET in patients with Parkinson's disease; a validation study. Neuroimage. Clinical. 37: 103347. PMID 36822016 DOI: 10.1016/j.nicl.2023.103347 |
0.372 |
|
| 2022 |
Wakabayashi Y, Strenkona P, Arakawa R, Yan X, Van Buskirk MG, Jenkins MD, Montero Santamaria JA, Maresca KP, Takano A, Liow JS, Chappie TA, Varrone A, Nag S, Zhang L, Hughes ZA, et al. First-in-human evaluation of F-PF-06445974, a PET radioligand that preferentially labels phosphodiesterase-4B. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 35772961 DOI: 10.2967/jnumed.122.263838 |
0.363 |
|
| 2022 |
Guedj E, Varrone A, Boellaard R, Albert NL, Barthel H, van Berckel B, Brendel M, Cecchin D, Ekmekcioglu O, Garibotto V, Lammertsma AA, Law I, Peñuelas I, Semah F, Traub-Weidinger T, et al. Correction to: EANM procedure guidelines for brain PET imaging using [F]FDG, version 3. European Journal of Nuclear Medicine and Molecular Imaging. 49: 2100-2101. PMID 35254483 DOI: 10.1007/s00259-022-05755-3 |
0.365 |
|
| 2022 |
Varrone A, Bundgaard C, Bang-Andersen B. PET as a Translational Tool in Drug Development for Neuroscience Compounds. Clinical Pharmacology and Therapeutics. 111: 774-785. PMID 35201613 DOI: 10.1002/cpt.2548 |
0.309 |
|
| 2021 |
Mo SJ, Axelsson J, Stiernman LJ, Larsson A, Af Bjerkén S, Bäckström D, Kellgren TG, Varrone A, Riklund K. VNTR polymorphism in the SLC6A3 gene does not influence dopamine transporter availability measured by [18F]FE-PE2I PET or [123I]FP-Cit SPECT. Nuclear Medicine Communications. PMID 34908018 DOI: 10.1097/MNM.0000000000001514 |
0.322 |
|
| 2021 |
Guedj E, Varrone A, Boellaard R, Albert NL, Barthel H, van Berckel B, Brendel M, Cecchin D, Ekmekcioglu O, Garibotto V, Lammertsma AA, Law I, Peñuelas I, Semah F, Traub-Weidinger T, et al. EANM procedure guidelines for brain PET imaging using [F]FDG, version 3. European Journal of Nuclear Medicine and Molecular Imaging. PMID 34882261 DOI: 10.1007/s00259-021-05603-w |
0.383 |
|
| 2021 |
Nag S, Jahan M, Tóth M, Nakao R, Varrone A, Halldin C. PET Imaging of VMAT2 with the Novel Radioligand [F]FE-DTBZ-d4 in Nonhuman Primates: Comparison with [C]DTBZ and [F]FE-DTBZ. Acs Chemical Neuroscience. 12: 4580-4586. PMID 34813272 DOI: 10.1021/acschemneuro.1c00651 |
0.337 |
|
| 2021 |
Veldman ER, Varrone A, Varnäs K, Svedberg MM, Cselényi Z, Tiger M, Gulyás B, Halldin C, Lundberg J. Serotonin 1B receptor density mapping of the human brainstem using positron emission tomography and autoradiography. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X211049185. PMID 34644198 DOI: 10.1177/0271678X211049185 |
0.556 |
|
| 2021 |
Liu L, Johnson PD, Prime ME, Khetarpal V, Lee MR, Brown CJ, Chen X, Clark-Frew D, Coe S, Conlon M, Davis R, Ensor S, Esposito S, Moren AF, Gai X, ... ... Varrone A, et al. [C]CHDI-626, a PET Tracer Candidate for Imaging Mutant Huntingtin Aggregates with Reduced Binding to AD Pathological Proteins. Journal of Medicinal Chemistry. PMID 34351166 DOI: 10.1021/acs.jmedchem.1c00667 |
0.31 |
|
| 2020 |
Miranda-Azpiazu P, Svedberg M, Higuchi M, Ono M, Jia Z, Sunnemark D, Elmore CS, Schou M, Varrone A. Identification and in vitro characterization of C05-01, a PPB3 derivative with improved affinity for alpha-synuclein. Brain Research. 1749: 147131. PMID 32956648 DOI: 10.1016/J.Brainres.2020.147131 |
0.348 |
|
| 2020 |
Brumberg J, Kerstens V, Cselényi Z, Svenningsson P, Sundgren M, Fazio P, Varrone A. Simplified quantification of [F]FE-PE2I PET in Parkinson's disease: Discriminative power, test-retest reliability and longitudinal validity during early peak and late pseudo-equilibrium. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X20958755. PMID 32955955 DOI: 10.1177/0271678X20958755 |
0.411 |
|
| 2020 |
Kerstens VS, Fazio P, Sundgren M, Matheson GJ, Franzén E, Halldin C, Cervenka S, Svenningsson P, Varrone A. Reliability of dopamine transporter PET measurements with [F]FE-PE2I in patients with Parkinson's disease. Ejnmmi Research. 10: 95. PMID 32797307 DOI: 10.1186/S13550-020-00676-4 |
0.402 |
|
| 2020 |
Morbelli S, Ekmekcioglu O, Barthel H, Albert NL, Boellaard R, Cecchin D, Guedj E, Lammertsma AA, Law I, Penuelas I, Semah F, Traub-Weidinger T, van de Giessen E, Varrone A, Garibotto V, et al. COVID-19 and the brain: impact on nuclear medicine in neurology. European Journal of Nuclear Medicine and Molecular Imaging. PMID 32700058 DOI: 10.1007/S00259-020-04965-X |
0.317 |
|
| 2020 |
Laurell GL, Plavén-Sigray P, Jucaite A, Varrone A, Cosgrove KP, Svarer C, Knudsen GM, Ogden RT, Zanderigo F, Cervenka S, Hillmer AT, Schain M. Non-displaceable binding is a potential confounding factor in CPBR28 TSPO PET studies. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 32680926 DOI: 10.2967/Jnumed.120.243717 |
0.426 |
|
| 2020 |
Cselényi Z, Jucaite A, Kristensson C, Stenkrona P, Ewing P, Varrone A, Johnström P, Schou M, Vazquez-Romero A, Moein MM, Bolin M, Siikanen J, Grybäck P, Larsson B, Halldin C, et al. Quantification and reliability of [C]VC - 002 binding to muscarinic acetylcholine receptors in the human lung - a test-retest PET study in control subjects. Ejnmmi Research. 10: 59. PMID 32495011 DOI: 10.1186/S13550-020-00634-0 |
0.381 |
|
| 2020 |
Arakawa R, Takano A, Stenkrona P, Stepanov V, Nag S, Jahan M, Grybäck P, Bolin M, Chen L, Zhang L, He P, Villalobos A, McCarthy TJ, Halldin C, Varrone A. PET imaging of beta-secretase 1 in the human brain: radiation dosimetry, quantification, and test-retest examination of [F]PF-06684511. European Journal of Nuclear Medicine and Molecular Imaging. PMID 32140803 DOI: 10.1007/S00259-020-04739-5 |
0.479 |
|
| 2020 |
Fazio P, Ferreira D, Svenningsson P, Halldin C, Farde L, Westman E, Varrone A. High-resolution PET imaging reveals subtle impairment of the serotonin transporter in an early non-depressed Parkinson's disease cohort. European Journal of Nuclear Medicine and Molecular Imaging. PMID 32020370 DOI: 10.1007/S00259-020-04683-4 |
0.396 |
|
| 2020 |
Fazio P, Fitzer-Attas CJ, Mrzljak L, Bronzova J, Nag S, Warner JH, Landwehrmeyer B, Al-Tawil N, Halldin C, Forsberg A, Ware J, Dilda V, Wood A, Sampaio C, Varrone A, et al. PET molecular imaging of phosphodiesterase 10A: An early biomarker of Huntington's disease progression. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 31967355 DOI: 10.1002/Mds.27963 |
0.304 |
|
| 2020 |
Moein MM, Tóth M, Tari L, Varrone A, Abdel-Rehim M, Halldin C. New approach in radiometabolite analysis of positron emission tomography (PET) radioligands; lead-shielded microextraction by packed sorbent as a tool for in vivo radiometabolite analysis of [C]SMW139 in rat plasma. Talanta. 208: 120449. PMID 31816716 DOI: 10.1016/J.Talanta.2019.120449 |
0.398 |
|
| 2020 |
Kerstens VS, Varrone A. Dopamine transporter imaging in neurodegenerative movement disorders: PET vs. SPECT Clinical and Translational Imaging. 8: 349-356. DOI: 10.1007/s40336-020-00386-w |
0.364 |
|
| 2019 |
Tuisku J, Plavén-Sigray P, Gaiser EC, Airas L, Al-Abdulrasul H, Brück A, Carson RE, Chen MK, Cosgrove KP, Ekblad L, Esterlis I, Farde L, Forsberg A, Halldin C, Helin S, ... ... Varrone A, et al. Effects of age, BMI and sex on the glial cell marker TSPO - a multicentre [C]PBR28 HRRT PET study. European Journal of Nuclear Medicine and Molecular Imaging. PMID 31363804 DOI: 10.1007/S00259-019-04403-7 |
0.381 |
|
| 2019 |
Sarnyai Z, Nagy K, Patay G, Molnár M, Rosenqvist G, Tóth M, Takano A, Gulyás B, Major P, Halldin C, Varrone A. Performance Evaluation of a High Resolution Non-Human Primate PET/CT System. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 31302634 DOI: 10.2967/Jnumed.117.206243 |
0.611 |
|
| 2019 |
Varrone A, Varnäs K, Jucaite A, Cselényi Z, Johnström P, Schou M, Vazquez-Romero A, Moein MM, Halldin C, Brown AP, Vishwanathan K, Farde L. A PET study in healthy subjects of brain exposure of C-labelled osimertinib - A drug intended for treatment of brain metastases in non-small cell lung cancer. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X19843776. PMID 31006308 DOI: 10.1177/0271678X19843776 |
0.412 |
|
| 2019 |
Artelsmair M, Miranda-Azpiazu P, Kingston L, Bergare J, Schou M, Varrone A, Elmore CS. Synthesis, H-labelling and in vitro evaluation of a substituted dipiperidine alcohol as a potential ligand for chemokine receptor 2. Journal of Labelled Compounds & Radiopharmaceuticals. PMID 30937946 DOI: 10.1002/Jlcr.3731 |
0.323 |
|
| 2019 |
Svedberg MM, Varnäs K, Varrone A, Mitsios N, Mulder J, Gulyás B, Beaumont V, Munoz-Sanjuan I, Zaleska MM, Schmidt CJ, Halldin C, Mrzljak L. In vitro phosphodiesterase 10A (PDE10A) binding in whole hemisphere human brain using the PET radioligand [F]MNI-659. Brain Research. PMID 30664847 DOI: 10.1016/J.Brainres.2019.01.021 |
0.616 |
|
| 2018 |
Jakobson Mo S, Axelsson J, Jonasson L, Larsson A, Ögren MJ, Ögren M, Varrone A, Eriksson L, Bäckström D, Af Bjerkén S, Linder J, Riklund K. Dopamine transporter imaging with [F]FE-PE2I PET and [I]FP-CIT SPECT-a clinical comparison. Ejnmmi Research. 8: 100. PMID 30443684 DOI: 10.1186/S13550-018-0450-0 |
0.451 |
|
| 2018 |
Varrone A, Pellecchia MT. SPECT Molecular Imaging in Familial Parkinson's Disease. International Review of Neurobiology. 142: 225-260. PMID 30409254 DOI: 10.1016/Bs.Irn.2018.09.004 |
0.339 |
|
| 2018 |
Varnäs K, Cselényi Z, Jucaite A, Halldin C, Svenningsson P, Farde L, Varrone A. PET imaging of [C]PBR28 in Parkinson's disease patients does not indicate increased binding to TSPO despite reduced dopamine transporter binding. European Journal of Nuclear Medicine and Molecular Imaging. PMID 30270409 DOI: 10.1007/S00259-018-4161-6 |
0.407 |
|
| 2018 |
Cairns AG, Vazquez-Romero A, Mahdi-Moein M, Åden J, Elmore CS, Takano A, Arakawa R, Varrone A, Almqvist F, Schou M. Increased brain exposure of an alpha-synuclein fibrillization modulator by utilization of an activated ester pro-drug strategy. Acs Chemical Neuroscience. PMID 29901990 DOI: 10.1021/Acschemneuro.8B00236 |
0.387 |
|
| 2018 |
Chiotis K, Stenkrona P, Almkvist O, Stepanov V, Ferreira D, Arakawa R, Takano A, Westman E, Varrone A, Okamura N, Shimada H, Higuchi M, Halldin C, Nordberg A. Dual tracer tau PET imaging reveals different molecular targets for C-THK5351 and C-PBB3 in the Alzheimer brain. European Journal of Nuclear Medicine and Molecular Imaging. PMID 29752516 DOI: 10.1007/S00259-018-4012-5 |
0.438 |
|
| 2018 |
Fazio P, Svenningsson P, Cselényi Z, Halldin C, Farde L, Varrone A. Nigrostriatal dopamine transporter availability in early Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 29436751 DOI: 10.1002/Mds.27316 |
0.369 |
|
| 2018 |
Lizana H, Johansson L, Axelsson JE, Larsson Strömvall A, Ögren M, Linder J, Halldin C, Varrone A, Mo SJ. Whole-body biodistribution and dosimetry of the dopamine transporter radioligand 18F-FE-PE2I in human subjects. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 29348315 DOI: 10.2967/Jnumed.117.197186 |
0.446 |
|
| 2018 |
Vishwanathan K, Varrone A, Varnas K, Jucaite A, Cselenyi Z, Johnstrom P, Schou M, Vasquez-Romero A, Moein MM, Halldin C, Brown AP, Farde L. Abstract CT013: Osimertinib displays high brain exposure in healthy subjects with intact blood-brain barrier: a microdose positron emission tomography (PET) study with 11C-labelled osimertinib Cancer Research. 78. DOI: 10.1158/1538-7445.Am2018-Ct013 |
0.392 |
|
| 2017 |
Odano I, Varrone A, Hosoya T, Sakaguchi K, Gulyás B, Padmanabhan P, Ghosh KK, Yang CT, Guenther I, Wang Z, Serrano R, Chimon NG, Halldin C. Simplified estimation of binding parameters based on image-derived reference tissue models for dopamine transporter bindings in non-human primates using [18F]FE-PE2I and PET. American Journal of Nuclear Medicine and Molecular Imaging. 7: 246-254. PMID 29348979 |
0.548 |
|
| 2017 |
Schain M, Fazio P, Mrzljak L, Amini N, Al-Tawil N, Fitzer-Attas C, Bronzova J, Landwehrmeyer B, Sampaio C, Halldin C, Varrone A. Revisiting the Logan plot to account for non-negligible blood volume in brain tissue. Ejnmmi Research. 7: 66. PMID 28822101 DOI: 10.1186/S13550-017-0314-Z |
0.333 |
|
| 2017 |
Matheson GJ, Plavén-Sigray P, Forsberg A, Varrone A, Farde L, Cervenka S. Assessment of simplified ratio-based approaches for quantification of PET [(11)C]PBR28 data. Ejnmmi Research. 7: 58. PMID 28733954 DOI: 10.1186/S13550-017-0304-1 |
0.411 |
|
| 2017 |
Chiotis K, Saint-Aubert L, Boccardi M, Gietl A, Picco A, Varrone A, Garibotto V, Herholz K, Nobili F, Nordberg A. Clinical validity of increased cortical uptake of amyloid ligands on PET as a biomarker for Alzheimer's disease in the context of a structured 5-phase development framework. Neurobiology of Aging. 52: 214-227. PMID 28317650 DOI: 10.1016/J.Neurobiolaging.2016.07.012 |
0.369 |
|
| 2017 |
Garibotto V, Herholz K, Boccardi M, Picco A, Varrone A, Nordberg A, Nobili F, Ratib O. Clinical validity of brain fluorodeoxyglucose positron emission tomography as a biomarker for Alzheimer's disease in the context of a structured 5-phase development framework. Neurobiology of Aging. 52: 183-195. PMID 28317648 DOI: 10.1016/J.Neurobiolaging.2016.03.033 |
0.38 |
|
| 2017 |
Fazio P, Schain M, Mrzljak L, Amini N, Nag S, Al-Tawil N, Fitzer-Attas CJ, Bronzova J, Landwehrmeyer B, Sampaio C, Halldin C, Varrone A. Patterns of age related changes for phosphodiesterase type-10A in comparison with dopamine D2/3 receptors and sub-cortical volumes in the human basal ganglia: a PET study with (18)F-MNI-659 and (11)C-raclopride with correction for partial volume effect. Neuroimage. PMID 28254508 DOI: 10.1016/J.Neuroimage.2017.02.047 |
0.419 |
|
| 2017 |
Forsberg A, Cervenka S, Jonsson Fagerlund M, Rasmussen LS, Zetterberg H, Erlandsson Harris H, Stridh P, Christensson E, Granström A, Schening A, Dymmel K, Knave N, Terrando N, Maze M, Borg J, ... Varrone A, et al. The immune response of the human brain to abdominal surgery. Annals of Neurology. PMID 28253549 DOI: 10.1002/Ana.24909 |
0.325 |
|
| 2017 |
Tossici-Bolt L, Dickson JC, Sera T, Booij J, Asenbaun-Nan S, Bagnara MC, Borght TV, Jonsson C, de Nijs R, Hesse S, Koulibaly PM, Akdemir UO, Koole M, Tatsch K, Varrone A. [(123)I]FP-CIT ENC-DAT normal database: the impact of the reconstruction and quantification methods. Ejnmmi Physics. 4: 8. PMID 28130765 DOI: 10.1186/S40658-017-0175-6 |
0.333 |
|
| 2017 |
Delnomdedieu M, Forsberg A, Ogden A, Fazio P, Yu CR, Stenkrona P, Duvvuri S, David W, Al-Tawil N, Vitolo OV, Amini N, Nag S, Halldin C, Varrone A. In vivo measurement of PDE10A enzyme occupancy by positron emission tomography (PET) following single oral dose administration of PF-02545920 in healthy male subjects. Neuropharmacology. PMID 28122201 DOI: 10.1016/J.Neuropharm.2017.01.016 |
0.333 |
|
| 2017 |
Dickson JC, Tossici-Bolt L, Sera T, Booij J, Ziebell M, Morbelli S, Assenbaum-Nan S, Borght TV, Pagani M, Kapucu OL, Hesse S, Van Laere K, Darcourt J, Varrone A, Tatsch K. The impact of reconstruction and scanner characterisation on the diagnostic capability of a normal database for [(123)I]FP-CIT SPECT imaging. Ejnmmi Research. 7: 10. PMID 28120177 DOI: 10.1186/S13550-016-0253-0 |
0.316 |
|
| 2017 |
Chiotis K, Stenkrona P, Almkvist O, Arakawa R, Takano A, Stepanov V, Varrone A, Higuchi M, Halldin C, Nordberg A. [IC-P-178]: HEAD-TO-HEAD IN VIVO
COMPARISON OF TAU-SPECIFIC PET TRACERS IN ALZHEIMER's DISEASE: [11
C]THK5351 VERSUS [11
C]PBB3 PET IMAGING Alzheimer's & Dementia. 13: P133-P133. DOI: 10.1016/J.Jalz.2017.06.2553 |
0.419 |
|
| 2016 |
Häggkvist J, Tóth M, Tari L, Varnäs K, Svedberg M, Forsberg A, Nag S, Dominguez C, Munoz-Sanjuan I, Bard J, Wityak J, Varrone A, Halldin C, Mrzljak L. Longitudinal microPET imaging of the zQ175 mouse model of Huntington's disease shows in vivo changes of molecular targets in the striatum and the cerebral cortex. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 27856625 DOI: 10.2967/Jnumed.116.180497 |
0.364 |
|
| 2016 |
Sturm S, Forsberg A, Nave S, Stenkrona P, Seneca N, Varrone A, Comley RA, Fazio P, Jamois C, Nakao R, Ejduk Z, Al-Tawil N, Akenine U, Halldin C, Andreasen N, et al. Positron emission tomography measurement of brain MAO-B inhibition in patients with Alzheimer's disease and elderly controls after oral administration of sembragiline. European Journal of Nuclear Medicine and Molecular Imaging. PMID 27633250 DOI: 10.1007/S00259-016-3510-6 |
0.322 |
|
| 2016 |
Takano A, Varrone A, Gulyás B, Salvadori P, Gee A, Windhorst A, Vercouillie J, Bormans G, Lammertsma AA, Halldin C. Guidelines to PET measurements of the target occupancy in the brain for drug development. European Journal of Nuclear Medicine and Molecular Imaging. PMID 27514528 DOI: 10.1007/S00259-016-3476-4 |
0.528 |
|
| 2016 |
Tiger M, Farde L, Rück C, Varrone A, Forsberg A, Lindefors N, Halldin C, Lundberg J. Low serotonin1B receptor binding potential in the anterior cingulate cortex in drug-free patients with recurrent major depressive disorder. Psychiatry Research. 253: 36-42. PMID 27269199 DOI: 10.1016/J.Pscychresns.2016.04.016 |
0.395 |
|
| 2016 |
Sonni I, Fazio P, Schain M, Halldin C, Svenningsson P, Farde L, Varrone A. Optimal acquisition time window and simplified quantification of dopamine transporter availability using 18F-FE-PE2I in healthy controls and Parkinson's disease patients. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 27230923 DOI: 10.2967/Jnumed.115.171231 |
0.421 |
|
| 2016 |
Fazio P, Schain M, Varnäs K, Halldin C, Farde L, Varrone A. Mapping the distribution of serotonin transporter in the human brainstem with high resolution PET: Validation using post-mortem autoradiography data. Neuroimage. PMID 26994829 DOI: 10.1016/J.Neuroimage.2016.03.019 |
0.434 |
|
| 2016 |
Kanegawa N, Collste K, Forsberg A, Schain M, Arakawa R, Jucaite A, Lekander M, Höglund CO, Kosek E, Lampa J, Halldin C, Farde L, Varrone A, Cervenka S. In vivo evidence of a functional association between immune cells in blood and brain in healthy human subjects. Brain, Behavior, and Immunity. PMID 26820224 DOI: 10.1016/J.Bbi.2016.01.019 |
0.389 |
|
| 2016 |
Buchert R, Kluge A, Tossici-Bolt L, Dickson J, Bronzel M, Lange C, Asenbaum S, Booij J, Atay Kapucu LÖ, Svarer C, Koulibaly PM, Nobili F, Pagani M, Sabri O, Sera T, ... ... Varrone A, et al. Reduction in camera-specific variability in [(123)I]FP-CIT SPECT outcome measures by image reconstruction optimized for multisite settings: impact on age-dependence of the specific binding ratio in the ENC-DAT database of healthy controls. European Journal of Nuclear Medicine and Molecular Imaging. PMID 26816194 DOI: 10.1007/S00259-016-3309-5 |
0.385 |
|
| 2016 |
Kanegawa N, Collste K, Forsberg A, Schain M, Arakawa R, Jucaite A, Lekander M, Höglund CO, Kosek E, Lampa J, Halldin C, Farde L, Varrone A, Cervenka S. Abstract # 1847 Cross-sectional and longitudinal associations between immune cells in blood and brain – A TSPO PET study in healthy control subjects Brain, Behavior, and Immunity. 57: e38. DOI: 10.1016/J.Bbi.2016.07.127 |
0.39 |
|
| 2015 |
Nag S, Fazio P, Lehmann L, Kettschau G, Heinrich T, Thiele A, Svedberg M, Amini N, Leesch S, Catafau A, Hannestad J, Varrone A, Halldin C. In Vivo/In Vitro Characterisation of a Novel MAO-B Inhibitor Radioligand, Fluorine-18 Labeled Deuterated Fluorodeprenyl (18F-Fluorodeprenyl-D2). Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 26585057 DOI: 10.2967/Jnumed.115.161083 |
0.36 |
|
| 2015 |
Collste K, Forsberg A, Varrone A, Amini N, Aeinehband S, Yakushev I, Halldin C, Farde L, Cervenka S. Test-retest reproducibility of [(11)C]PBR28 binding to TSPO in healthy control subjects. European Journal of Nuclear Medicine and Molecular Imaging. PMID 26293827 DOI: 10.1007/S00259-015-3149-8 |
0.399 |
|
| 2015 |
Jucaite A, Svenningsson P, Rinne JO, Cselényi Z, Varnäs K, Johnström P, Amini N, Kirjavainen A, Helin S, Minkwitz M, Kugler AR, Posener JA, Budd S, Halldin C, Varrone A, et al. Effect of the myeloperoxidase inhibitor AZD3241 on microglia: a PET study in Parkinson's disease. Brain : a Journal of Neurology. 138: 2687-700. PMID 26137956 DOI: 10.1093/Brain/Awv184 |
0.381 |
|
| 2015 |
Tóth M, Doorduin J, Häggkvist J, Varrone A, Amini N, Halldin C, Gulyás B. Positron Emission Tomography studies with [11C]PBR28 in the Healthy Rodent Brain: Validating SUV as an Outcome Measure of Neuroinflammation. Plos One. 10: e0125917. PMID 25996996 DOI: 10.1371/Journal.Pone.0125917 |
0.62 |
|
| 2015 |
Varrone A, Svenningsson P, Marklund P, Fatouros-Bergman H, Forsberg A, Halldin C, Nilsson LG, Farde L. 5-HT1B receptor imaging and cognition: a positron emission tomography study in control subjects and Parkinson's disease patients. Synapse (New York, N.Y.). 69: 365-74. PMID 25914348 DOI: 10.1002/Syn.21823 |
0.338 |
|
| 2015 |
Fazio P, Svenningsson P, Forsberg A, Jönsson EG, Amini N, Nakao R, Nag S, Halldin C, Farde L, Varrone A. Quantitative Analysis of ¹⁸F-(E)-N-(3-Iodoprop-2-Enyl)-2β-Carbofluoroethoxy-3β-(4'-Methyl-Phenyl) Nortropane Binding to the Dopamine Transporter in Parkinson Disease. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 56: 714-20. PMID 25791993 DOI: 10.2967/Jnumed.114.152421 |
0.385 |
|
| 2015 |
Matheson GJ, Schain M, Almeida R, Lundberg J, Cselényi Z, Borg J, Varrone A, Farde L, Cervenka S. Diurnal and seasonal variation of the brain serotonin system in healthy male subjects. Neuroimage. 112: 225-31. PMID 25772667 DOI: 10.1016/J.Neuroimage.2015.03.007 |
0.354 |
|
| 2015 |
Paul G, Zachrisson O, Varrone A, Almqvist P, Jerling M, Lind G, Rehncrona S, Linderoth B, Bjartmarz H, Shafer LL, Coffey R, Svensson M, Mercer KJ, Forsberg A, Halldin C, et al. Safety and tolerability of intracerebroventricular PDGF-BB in Parkinson's disease patients. The Journal of Clinical Investigation. 125: 1339-46. PMID 25689258 DOI: 10.1172/Jci79635 |
0.317 |
|
| 2015 |
Finnema SJ, Hughes ZA, Haaparanta-Solin M, Stepanov V, Nakao R, Varnäs K, Varrone A, Arponen E, Marjamäki P, Pohjanoksa K, Vuorilehto L, Babalola PA, Solin O, Grimwood S, Sallinen J, et al. Amphetamine decreases α2C-adrenoceptor binding of [11C]ORM-13070: a PET study in the primate brain. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 18. PMID 25522417 DOI: 10.1093/Ijnp/Pyu081 |
0.364 |
|
| 2015 |
Varrone A, Oikonen V, Forsberg A, Joutsa J, Takano A, Solin O, Haaparanta-Solin M, Nag S, Nakao R, Al-Tawil N, Wells LA, Rabiner EA, Valencia R, Schultze-Mosgau M, Thiele A, et al. Positron emission tomography imaging of the 18-kDa translocator protein (TSPO) with [18F]FEMPA in Alzheimer's disease patients and control subjects. European Journal of Nuclear Medicine and Molecular Imaging. 42: 438-46. PMID 25412766 DOI: 10.1007/S00259-014-2955-8 |
0.422 |
|
| 2015 |
Tóth M, Doorduin J, Häggkvist J, Varrone A, Amini N, Halldin C, Gulyás B. Positron emission tomography studies with [11C]PBR28 in the healthy rodent brain: Validating SUV as an outcome measure of neuroinflammation Plos One. 10. DOI: 10.1371/journal.pone.0125917 |
0.528 |
|
| 2015 |
Varrone A, Nordberg A. Molecular imaging of neuroinflammation in Alzheimer’s disease Clinical and Translational Imaging. 3: 437-447. DOI: 10.1007/S40336-015-0137-8 |
0.389 |
|
| 2014 |
Tóth M, Häggkvist J, Varrone A, Finnema SJ, Doorduin J, Tokunaga M, Higuchi M, Gulyás B, Halldin C. ABC transporter-dependent brain uptake of the 5-HT1B receptor radioligand [ (11)C]AZ10419369: a comparative PET study in mouse, rat, and guinea pig. Ejnmmi Research. 4: 64. PMID 26116125 DOI: 10.1186/S13550-014-0064-0 |
0.596 |
|
| 2014 |
Nord M, Cselenyi Z, Forsberg A, Rosenqvist G, Tiger M, Lundberg J, Varrone A, Farde L. Distinct regional age effects on [11C]AZ10419369 binding to 5-HT1B receptors in the human brain. Neuroimage. 103: 303-8. PMID 25255943 DOI: 10.1016/J.Neuroimage.2014.09.040 |
0.317 |
|
| 2014 |
Tiger M, Rück C, Forsberg A, Varrone A, Lindefors N, Halldin C, Farde L, Lundberg J. Reduced 5-HT(1B) receptor binding in the dorsal brain stem after cognitive behavioural therapy of major depressive disorder. Psychiatry Research. 223: 164-70. PMID 24916155 DOI: 10.1016/J.Pscychresns.2014.05.011 |
0.382 |
|
| 2014 |
Schain M, Varnäs K, Cselényi Z, Halldin C, Farde L, Varrone A. Evaluation of two automated methods for PET region of interest analysis. Neuroinformatics. 12: 551-62. PMID 24880728 DOI: 10.1007/S12021-014-9233-6 |
0.397 |
|
| 2014 |
Koch W, Unterrainer M, Xiong G, Bartenstein P, Diemling M, Varrone A, Dickson JC, Tossici-Bolt L, Sera T, Asenbaum S, Booij J, Kapucu OL, Kluge A, Ziebell M, Darcourt J, et al. Extrastriatal binding of [¹²³I]FP-CIT in the thalamus and pons: gender and age dependencies assessed in a European multicentre database of healthy controls. European Journal of Nuclear Medicine and Molecular Imaging. 41: 1938-46. PMID 24806112 DOI: 10.1007/S00259-014-2785-8 |
0.386 |
|
| 2014 |
Suzuki M, Ito H, Kodaka F, Takano H, Kimura Y, Fujiwara H, Sasaki T, Takahata K, Nogami T, Nagashima T, Nengaki N, Kawamura K, Zhang MR, Varrone A, Halldin C, et al. Reproducibility of PET measurement for presynaptic dopaminergic functions using L-[β-(11)C]DOPA and [(18)F]FE-PE2I in humans. Nuclear Medicine Communications. 35: 231-7. PMID 24468851 DOI: 10.1097/Mnm.0000000000000052 |
0.428 |
|
| 2014 |
Varrone A, Svenningsson P, Forsberg A, Varnäs K, Tiger M, Nakao R, Halldin C, Nilsson LG, Farde L. Positron emission tomography imaging of 5-hydroxytryptamine1B receptors in Parkinson's disease. Neurobiology of Aging. 35: 867-75. PMID 24126162 DOI: 10.1016/J.Neurobiolaging.2013.08.025 |
0.332 |
|
| 2014 |
Tóth M, Häggkvist J, Varrone A, Finnema SJ, Doorduin J, Tokunaga M, Higuchi M, Gulyás B, Halldin C. ABC transporter-dependent brain uptake of the 5-HT1B receptor radioligand [11C]AZ10419369: a comparative PET study in mouse, rat, and guinea pig Ejnmmi Research. 4. DOI: 10.1186/s13550-014-0064-0 |
0.56 |
|
| 2014 |
Fazio P, Fitzer-Attas C, Mrzljak L, Martinsson S, Landwehrmeyer G, Bronzova J, Al-Tawil N, Halldin C, Sampaio C, Varrone A. E31 Positron Emission Tomography Imaging Of Phosphodiesterase 10 A Enzyme And Dopamine D2 Receptor In Huntington's Disease Gene Expansion Carriers Journal of Neurology, Neurosurgery & Psychiatry. 85: A47-A47. DOI: 10.1136/Jnnp-2014-309032.134 |
0.464 |
|
| 2013 |
Nag S, Lehmann L, Kettschau G, Toth M, Heinrich T, Thiele A, Varrone A, Halldin C. Development of a novel fluorine-18 labeled deuterated fluororasagiline ([(18)F]fluororasagiline-D2) radioligand for PET studies of monoamino oxidase B (MAO-B). Bioorganic & Medicinal Chemistry. 21: 6634-41. PMID 24012376 DOI: 10.1016/J.Bmc.2013.08.019 |
0.439 |
|
| 2013 |
Nagy K, Tóth M, Major P, Patay G, Egri G, Häggkvist J, Varrone A, Farde L, Halldin C, Gulyás B. Performance evaluation of the small-animal nanoScan PET/MRI system. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 54: 1825-32. PMID 23990683 DOI: 10.2967/Jnumed.112.119065 |
0.554 |
|
| 2013 |
Varnäs K, Varrone A, Farde L. Modeling of PET data in CNS drug discovery and development. Journal of Pharmacokinetics and Pharmacodynamics. 40: 267-79. PMID 23660778 DOI: 10.1007/S10928-013-9320-6 |
0.38 |
|
| 2013 |
Takano A, Piehl F, Hillert J, Varrone A, Nag S, Gulyás B, Stenkrona P, Villemagne VL, Rowe CC, Macdonell R, Tawil NA, Kucinski T, Zimmermann T, Schultze-Mosgau M, Thiele A, et al. In vivo TSPO imaging in patients with multiple sclerosis: a brain PET study with [18F]FEDAA1106. Ejnmmi Research. 3: 30. PMID 23618062 DOI: 10.1186/2191-219X-3-30 |
0.59 |
|
| 2013 |
Schain M, Benjaminsson S, Varnäs K, Forsberg A, Halldin C, Lansner A, Farde L, Varrone A. Arterial input function derived from pairwise correlations between PET-image voxels. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 33: 1058-65. PMID 23571279 DOI: 10.1038/Jcbfm.2013.47 |
0.391 |
|
| 2013 |
Varrone A, Mattsson P, Forsberg A, Takano A, Nag S, Gulyás B, Borg J, Boellaard R, Al-Tawil N, Eriksdotter M, Zimmermann T, Schultze-Mosgau M, Thiele A, Hoffmann A, Lammertsma AA, et al. In vivo imaging of the 18-kDa translocator protein (TSPO) with [18F]FEDAA1106 and PET does not show increased binding in Alzheimer's disease patients. European Journal of Nuclear Medicine and Molecular Imaging. 40: 921-31. PMID 23436070 DOI: 10.1007/S00259-013-2359-1 |
0.612 |
|
| 2013 |
Ikoma Y, Takano A, Varrone A, Halldin C. Graphic plot analysis for estimating binding potential of translocator protein (TSPO) in positron emission tomography studies with [¹â¸F]FEDAA1106. Neuroimage. 69: 78-86. PMID 23247191 DOI: 10.1016/J.Neuroimage.2012.12.009 |
0.345 |
|
| 2013 |
Tóth M, Varrone A, Steiger C, Laszlovszky I, Horváth A, Kiss B, Gyertyán I, Adham N, Halldin C, Gulyás B. Brain uptake and distribution of the dopamine D3 /D2 receptor partial agonist [11 C]cariprazine: an in vivo positron emission tomography study in nonhuman primates. Synapse (New York, N.Y.). 67: 258-64. PMID 23238770 DOI: 10.1002/Syn.21631 |
0.593 |
|
| 2013 |
Nobili F, Naseri M, De Carli F, Asenbaum S, Booij J, Darcourt J, Ell P, Kapucu O, Kemp P, Svarer C, Varer C, Morbelli S, Pagani M, Sabri O, Tatsch K, ... ... Varrone A, et al. Automatic semi-quantification of [123I]FP-CIT SPECT scans in healthy volunteers using BasGan version 2: results from the ENC-DAT database. European Journal of Nuclear Medicine and Molecular Imaging. 40: 565-73. PMID 23232506 DOI: 10.1007/S00259-012-2304-8 |
0.34 |
|
| 2013 |
Nag S, Kettschau G, Heinrich T, Varrone A, Lehmann L, Gulyas B, Thiele A, Keller É, Halldin C. Synthesis and biological evaluation of novel propargyl amines as potential fluorine-18 labeled radioligands for detection of MAO-B activity. Bioorganic & Medicinal Chemistry. 21: 186-95. PMID 23211968 DOI: 10.1016/J.Bmc.2012.10.050 |
0.544 |
|
| 2013 |
Varrone A, Dickson JC, Tossici-Bolt L, Sera T, Asenbaum S, Booij J, Kapucu OL, Kluge A, Knudsen GM, Koulibaly PM, Nobili F, Pagani M, Sabri O, Vander Borght T, Van Laere K, et al. European multicentre database of healthy controls for [123I]FP-CIT SPECT (ENC-DAT): age-related effects, gender differences and evaluation of different methods of analysis. European Journal of Nuclear Medicine and Molecular Imaging. 40: 213-27. PMID 23160999 DOI: 10.1007/S00259-012-2276-8 |
0.33 |
|
| 2013 |
Schain M, Tóth M, Cselényi Z, Arakawa R, Halldin C, Farde L, Varrone A. Improved mapping and quantification of serotonin transporter availability in the human brainstem with the HRRT. European Journal of Nuclear Medicine and Molecular Imaging. 40: 228-37. PMID 23076621 DOI: 10.1007/S00259-012-2260-3 |
0.446 |
|
| 2013 |
van de Giessen E, Hesse S, Caan MW, Zientek F, Dickson JC, Tossici-Bolt L, Sera T, Asenbaum S, Guignard R, Akdemir UO, Knudsen GM, Nobili F, Pagani M, Vander Borght T, Van Laere K, ... Varrone A, et al. No association between striatal dopamine transporter binding and body mass index: a multi-center European study in healthy volunteers. Neuroimage. 64: 61-7. PMID 22982354 DOI: 10.1016/J.Neuroimage.2012.09.011 |
0.313 |
|
| 2013 |
Paul G, Zachrisson O, Varrone A, Almqvist P, Jerling M, Lindh G, Rehncrona S, Linderoth B, Bjartmarz H, Svensson M, Mercer KJ, Forsberg A, Shafer LL, Lang AMJ, Halldin C, et al. Safety and efficacy of recombinant human platelet derived growth factor (Rhpdgf) in Parkinson's disease Journal of the Neurological Sciences. 333. DOI: 10.1016/J.Jns.2013.07.457 |
0.316 |
|
| 2013 |
Jucaite A, Cselényi Z, Varrone A, Varnäs K, Johnström P, Halldin C, Salter H, McLoughlin M, Rinne J, Svenningsson P, Alexander R, Kugler A, Farde L. 145. Translocator protein (TSPO) as a biomarker of microglia activation: PET imaging using [11C]PBR28 in Parkinson’s disease Brain, Behavior, and Immunity. 32: e42. DOI: 10.1016/J.Bbi.2013.07.157 |
0.501 |
|
| 2012 |
Brockschnieder D, Schmitt-Willich H, Heinrich T, Varrone A, Gulyás B, Toth M, Andersson J, Boemer U, Krause S, Friebe M, Dinkelborg L, Halldin C, Dyrks T. Preclinical characterization of a novel class of 18F-labeled PET tracers for amyloid-β. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 53: 1794-801. PMID 23008501 DOI: 10.2967/Jnumed.112.104810 |
0.612 |
|
| 2012 |
Sasaki T, Ito H, Kimura Y, Arakawa R, Takano H, Seki C, Kodaka F, Fujie S, Takahata K, Nogami T, Suzuki M, Fujiwara H, Takahashi H, Nakao R, Fukumura T, ... Varrone A, et al. Quantification of dopamine transporter in human brain using PET with 18F-FE-PE2I. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 53: 1065-73. PMID 22689927 DOI: 10.2967/Jnumed.111.101626 |
0.472 |
|
| 2012 |
Farkas S, Nagy K, Jia Z, Hortobágyi T, Varrone A, Halldin C, Csiba L, Gulyás B. Signal transduction pathway activity compensates dopamine Dâ‚‚/D₃ receptor density changes in Parkinson's disease: a preliminary comparative human brain receptor autoradiography study with [³H]raclopride and [³âµS]GTPγS. Brain Research. 1453: 56-63. PMID 22480734 DOI: 10.1016/J.Brainres.2012.03.014 |
0.559 |
|
| 2012 |
Varrone A, Halldin C. New developments of dopaminergic imaging in Parkinson's disease. The Quarterly Journal of Nuclear Medicine and Molecular Imaging : Official Publication of the Italian Association of Nuclear Medicine (Aimn) [and] the International Association of Radiopharmacology (Iar), [and] Section of the Society of Radiopharmaceutical Chemistry and Biology. 56: 68-82. PMID 22460161 |
0.355 |
|
| 2012 |
Nag S, Lehmann L, Kettschau G, Heinrich T, Thiele A, Varrone A, Gulyas B, Halldin C. Synthesis and evaluation of [¹â¸F]fluororasagiline, a novel positron emission tomography (PET) radioligand for monoamine oxidase B (MAO-B). Bioorganic & Medicinal Chemistry. 20: 3065-71. PMID 22436387 DOI: 10.1016/J.Bmc.2012.02.056 |
0.609 |
|
| 2012 |
Varrone A, Halldin C. New developments of dopaminergic imaging in Parkinson's disease. The Quarterly Journal of Nuclear Medicine and Molecular Imaging : Official Publication of the Italian Association of Nuclear Medicine (Aimn) [and] the International Association of Radiopharmacology (Iar), [and] Section of the Society of.... PMID 22402820 |
0.355 |
|
| 2012 |
Schain M, Tóth M, Cselényi Z, Stenkrona P, Halldin C, Farde L, Varrone A. Quantification of serotonin transporter availability with [11C]MADAM--a comparison between the ECAT HRRT and HR systems. Neuroimage. 60: 800-7. PMID 22227138 DOI: 10.1016/J.Neuroimage.2011.12.047 |
0.37 |
|
| 2012 |
Finnema SJ, Varrone A, Hwang TJ, Halldin C, Farde L. Confirmation of fenfluramine effect on 5-HT(1B) receptor binding of [(11)C]AZ10419369 using an equilibrium approach. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 32: 685-95. PMID 22167236 DOI: 10.1038/Jcbfm.2011.172 |
0.442 |
|
| 2012 |
Nag S, Varrone A, Tóth M, Thiele A, Kettschau G, Heinrich T, Lehmann L, Halldin C. In vivo evaluation in cynomolgus monkey brain and metabolism of [¹â¸F]fluorodeprenyl: a new MAO-B pet radioligand. Synapse (New York, N.Y.). 66: 323-30. PMID 22124971 DOI: 10.1002/Syn.21514 |
0.458 |
|
| 2012 |
Odano I, Varrone A, Savic I, Ciumas C, Karlsson P, Jucaite A, Halldin C, Farde L. Quantitative PET analyses of regional [11C]PE2I binding to the dopamine transporter--application to juvenile myoclonic epilepsy. Neuroimage. 59: 3582-93. PMID 22056530 DOI: 10.1016/J.Neuroimage.2011.10.067 |
0.457 |
|
| 2012 |
Varrone A, Gulyás B, Takano A, Stabin MG, Jonsson C, Halldin C. Simplified quantification and whole-body distribution of [18F]FE-PE2I in nonhuman primates: prediction for human studies. Nuclear Medicine and Biology. 39: 295-303. PMID 22033024 DOI: 10.1016/J.Nucmedbio.2011.08.004 |
0.577 |
|
| 2011 |
Varrone A, Stepanov V, Nakao R, Tóth M, Gulyás B, Emond P, Deloye JB, Vercouillie J, Stabin MG, Jonsson C, Guilloteau D, Halldin C. Imaging of the striatal and extrastriatal dopamine transporter with (18)F-LBT-999: quantification, biodistribution, and radiation dosimetry in nonhuman primates. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 52: 1313-21. PMID 21764797 DOI: 10.2967/Jnumed.111.089953 |
0.632 |
|
| 2011 |
Takano A, Gulyás B, Varrone A, Karlsson P, Sjoholm N, Larsson S, Jonsson C, Odh R, Sparks R, Al Tawil N, Hoffmann A, Zimmermann T, Thiele A, Halldin C. Biodistribution and radiation dosimetry of the 18 kDa translocator protein (TSPO) radioligand [18F]FEDAA1106: a human whole-body PET study. European Journal of Nuclear Medicine and Molecular Imaging. 38: 2058-65. PMID 21732107 DOI: 10.1007/S00259-011-1864-3 |
0.596 |
|
| 2011 |
Esmaeilzadeh M, Kullingsjö J, Ullman H, Varrone A, Tedroff J. Regional cerebral glucose metabolism after pridopidine (ACR16) treatment in patients with Huntington disease. Clinical Neuropharmacology. 34: 95-100. PMID 21586914 DOI: 10.1097/Wnf.0B013E31821C31D8 |
0.323 |
|
| 2011 |
Tossici-Bolt L, Dickson JC, Sera T, de Nijs R, Bagnara MC, Jonsson C, Scheepers E, Zito F, Seese A, Koulibaly PM, Kapucu OL, Koole M, Raith M, George J, Lonsdale MN, ... ... Varrone A, et al. Calibration of gamma camera systems for a multicentre European ¹²³I-FP-CIT SPECT normal database. European Journal of Nuclear Medicine and Molecular Imaging. 38: 1529-40. PMID 21468761 DOI: 10.1007/S00259-011-1801-5 |
0.337 |
|
| 2011 |
Gulyás B, Vas A, Tóth M, Takano A, Varrone A, Cselényi Z, Schain M, Mattsson P, Halldin C. Age and disease related changes in the translocator protein (TSPO) system in the human brain: positron emission tomography measurements with [11C]vinpocetine. Neuroimage. 56: 1111-21. PMID 21320609 DOI: 10.1016/J.Neuroimage.2011.02.020 |
0.594 |
|
| 2011 |
Varrone A, Tóth M, Steiger C, Takano A, Guilloteau D, Ichise M, Gulyás B, Halldin C. Kinetic analysis and quantification of the dopamine transporter in the nonhuman primate brain with 11C-PE2I and 18F-FE-PE2I. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 52: 132-9. PMID 21189414 DOI: 10.2967/Jnumed.110.077651 |
0.579 |
|
| 2011 |
Esmaeilzadeh M, Farde L, Karlsson P, Varrone A, Halldin C, Waters S, Tedroff J. Extrastriatal dopamine D(2) receptor binding in Huntington's disease. Human Brain Mapping. 32: 1626-36. PMID 20886576 DOI: 10.1002/Hbm.21134 |
0.387 |
|
| 2011 |
Varnäs K, Nyberg S, Halldin C, Varrone A, Takano A, Karlsson P, Andersson J, McCarthy D, Smith M, Pierson ME, Söderström J, Farde L. Quantitative analysis of [11C]AZ10419369 binding to 5-HT1B receptors in human brain. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 31: 113-23. PMID 20424633 DOI: 10.1038/Jcbfm.2010.55 |
0.416 |
|
| 2010 |
Varrone A, Halldin C. Molecular imaging of the dopamine transporter. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 51: 1331-4. PMID 20720060 DOI: 10.2967/Jnumed.109.065656 |
0.391 |
|
| 2010 |
Pappatà S, Varrone A, Vicidomini C, Milan G, De Falco C, Sansone V, Iavarone A, Comerci M, Loré E, Panico MR, Quarantelli M, Postiglione A, Salvatore M. SPECT imaging of GABA(A)/benzodiazepine receptors and cerebral perfusion in mild cognitive impairment. European Journal of Nuclear Medicine and Molecular Imaging. 37: 1156-63. PMID 20306034 DOI: 10.1007/S00259-010-1409-1 |
0.32 |
|
| 2010 |
Finnema SJ, Varrone A, Hwang TJ, Gulyás B, Pierson ME, Halldin C, Farde L. Fenfluramine-induced serotonin release decreases [11C]AZ10419369 binding to 5-HT1B-receptors in the primate brain. Synapse (New York, N.Y.). 64: 573-7. PMID 20222157 DOI: 10.1002/Syn.20780 |
0.566 |
|
| 2010 |
Cervenka S, Varrone A, Fransén E, Halldin C, Farde L. PET studies of D2-receptor binding in striatal and extrastriatal brain regions: Biochemical support in vivo for separate dopaminergic systems in humans. Synapse (New York, N.Y.). 64: 478-85. PMID 20175222 DOI: 10.1002/Syn.20765 |
0.434 |
|
| 2010 |
Van Laere K, Varrone A, Booij J, Vander Borght T, Nobili F, Kapucu OL, Walker Z, NÃ¥gren K, Tatsch K, Darcourt J. EANM procedure guidelines for brain neurotransmission SPECT/PET using dopamine D2 receptor ligands, version 2. European Journal of Nuclear Medicine and Molecular Imaging. 37: 434-42. PMID 19838704 DOI: 10.1007/S00259-009-1265-Z |
0.4 |
|
| 2010 |
Darcourt J, Booij J, Tatsch K, Varrone A, Vander Borght T, Kapucu OL, NÃ¥gren K, Nobili F, Walker Z, Van Laere K. EANM procedure guidelines for brain neurotransmission SPECT using (123)I-labelled dopamine transporter ligands, version 2. European Journal of Nuclear Medicine and Molecular Imaging. 37: 443-50. PMID 19838702 DOI: 10.1007/S00259-009-1267-X |
0.341 |
|
| 2010 |
Finnema S, Varrone A, Hwang T, Farde L, Halldin C. P.1.e.021 In vivo assessment of changes in serotonin release in the non-human primate brain using PET and [11C]AZ10419369 European Neuropsychopharmacology. 20: S299-S300. DOI: 10.1016/S0924-977X(10)70399-0 |
0.398 |
|
| 2010 |
Gulyás B, Tóth M, Varrone A, Horváth A, Laszlovszky I, Kiss B, Halldin C. BRAIN DISTRIBUTION AND BINDING OF [11C]CARIPRAZINE: IN VIVO PET STUDIES IN NON-HUMAN PRIMATES AND WHOLE HEMISPHERE POSTMORTEM AUTORADIOGRAPHIC STUDIES IN HUMAN BRAIN SLICES Schizophrenia Research. 117: 258-259. DOI: 10.1016/J.Schres.2010.02.405 |
0.6 |
|
| 2010 |
Varrone A, Tóth M, Steiger C, Takano A, Guilloteau D, Ichise M, Gulyás B, Halldin C. Kinetic analysis and quantification of the dopamine transporter in the non-human primate brain with [11C]PE2I and [18F]FE-PE2I Neuroimage. 52. DOI: 10.1016/J.Neuroimage.2010.04.137 |
0.431 |
|
| 2010 |
Nag S, Lehmann L, Kettschau G, Heinrich T, Brumby T, Thiele A, Varrone A, Gulyas B, Halldin C. Synthesis of three F-18 labeled analogues of l-deprenyl for PET studies of monoamine oxidase B Neuroimage. 52: S121. DOI: 10.1016/J.Neuroimage.2010.04.099 |
0.567 |
|
| 2010 |
Varrone A, Tóth M, Stepanov V, Nakao R, Gulyás B, Emond P, Deloye JB, Vercouillie J, Halldin C, Guilloteau D. Quantification of [18F]LBT-999 binding to the dopamine transporter in the rhesus monkey brain with the HRRT system Neuroimage. 52: S118-S119. DOI: 10.1016/J.Neuroimage.2010.04.097 |
0.602 |
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| 2010 |
Tóth M, Varrone A, Jia Z, Horváth A, Laszlovszky I, Kiss B, Halldin C, Gulyás B. PET studies in cynomolgous monkeys and whole hemisphere post mortem autoradiographic studies in human brain slices with the dopamine D2/D3 receptor ligand 11C-cariprazine Neuroimage. 52: S100. DOI: 10.1016/J.Neuroimage.2010.04.080 |
0.597 |
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| 2010 |
Finnema S, Varnäs K, Stepanov V, Varrone A, Gulyás B, Arponen E, Helin S, Solin O, Haaparanta M, Sallinen J, Ingman K, Scheinin M, Farde L, Halldin C. Amphetamine decreases binding of the novel alpha2C-adrenoreceptor radioligand [11C]ORM-13070 in monkey brain Neuroimage. 52: S61-S62. DOI: 10.1016/J.Neuroimage.2010.04.047 |
0.571 |
|
| 2009 |
Varrone A, Asenbaum S, Vander Borght T, Booij J, Nobili F, NÃ¥gren K, Darcourt J, Kapucu OL, Tatsch K, Bartenstein P, Van Laere K. EANM procedure guidelines for PET brain imaging using [18F]FDG, version 2. European Journal of Nuclear Medicine and Molecular Imaging. 36: 2103-10. PMID 19838705 DOI: 10.1007/S00259-009-1264-0 |
0.466 |
|
| 2009 |
Kapucu OL, Nobili F, Varrone A, Booij J, Vander Borght T, NÃ¥gren K, Darcourt J, Tatsch K, Van Laere KJ. EANM procedure guideline for brain perfusion SPECT using 99mTc-labelled radiopharmaceuticals, version 2. European Journal of Nuclear Medicine and Molecular Imaging. 36: 2093-102. PMID 19838703 DOI: 10.1007/S00259-009-1266-Y |
0.362 |
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| 2009 |
Schou M, Steiger C, Varrone A, Guilloteau D, Halldin C. Synthesis, radiolabeling and preliminary in vivo evaluation of [18F]FE-PE2I, a new probe for the dopamine transporter. Bioorganic & Medicinal Chemistry Letters. 19: 4843-5. PMID 19577467 DOI: 10.1016/J.Bmcl.2009.06.032 |
0.487 |
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| 2009 |
Takano A, Gulyás B, Varrone A, Halldin C. Comparative evaluations of norepinephrine transporter radioligands with reference tissue models in rhesus monkeys: (S,S)-[18F]FMeNER-D2 and (S,S)-[11C]MeNER. European Journal of Nuclear Medicine and Molecular Imaging. 36: 1885-91. PMID 19565240 DOI: 10.1007/S00259-009-1194-X |
0.581 |
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| 2009 |
Varrone A, Steiger C, Schou M, Takano A, Finnema SJ, Guilloteau D, Gulyás B, Halldin C. In vitro autoradiography and in vivo evaluation in cynomolgus monkey of [18F]FE-PE2I, a new dopamine transporter PET radioligand. Synapse (New York, N.Y.). 63: 871-80. PMID 19562698 DOI: 10.1002/Syn.20670 |
0.637 |
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| 2009 |
Varrone A, Sjöholm N, Eriksson L, Gulyás B, Halldin C, Farde L. Advancement in PET quantification using 3D-OP-OSEM point spread function reconstruction with the HRRT. European Journal of Nuclear Medicine and Molecular Imaging. 36: 1639-50. PMID 19437012 DOI: 10.1007/S00259-009-1156-3 |
0.636 |
|
| 2009 |
Takano A, Gulyás B, Varrone A, Maguire RP, Halldin C. Saturated norepinephrine transporter occupancy by atomoxetine relevant to clinical doses: a rhesus monkey study with (S,S)-[(18)F]FMeNER-D (2). European Journal of Nuclear Medicine and Molecular Imaging. 36: 1308-14. PMID 19300997 DOI: 10.1007/S00259-009-1118-9 |
0.602 |
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| 2009 |
McNab F, Varrone A, Farde L, Jucaite A, Bystritsky P, Forssberg H, Klingberg T. Changes in cortical dopamine D1 receptor binding associated with cognitive training. Science (New York, N.Y.). 323: 800-2. PMID 19197069 DOI: 10.1126/Science.1166102 |
0.303 |
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| 2009 |
Odano I, Halldin C, Karlsson P, Varrone A, Airaksinen AJ, Krasikova RN, Farde L. [18F]flumazenil binding to central benzodiazepine receptor studies by PET--quantitative analysis and comparisons with [11C]flumazenil. Neuroimage. 45: 891-902. PMID 19136064 DOI: 10.1016/J.Neuroimage.2008.12.005 |
0.486 |
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| 2009 |
Pellecchia MT, Barone P, Mollica C, Salvatore E, Ianniciello M, Longo K, Varrone A, Vicidomini C, Picillo M, De Michele G, Filla A, Salvatore M, Pappatà S. Diffusion-weighted imaging in multiple system atrophy: a comparison between clinical subtypes. Movement Disorders : Official Journal of the Movement Disorder Society. 24: 689-96. PMID 19117367 DOI: 10.1002/Mds.22440 |
0.325 |
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| 2008 |
Takano A, Varrone A, Gulyás B, Karlsson P, Tauscher J, Halldin C. Mapping of the norepinephrine transporter in the human brain using PET with (S,S)-[18F]FMeNER-D2. Neuroimage. 42: 474-82. PMID 18617423 DOI: 10.1016/J.Neuroimage.2008.05.040 |
0.647 |
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| 2008 |
Jovanovic H, Lundberg J, Karlsson P, Cerin A, Saijo T, Varrone A, Halldin C, Nordström AL. Sex differences in the serotonin 1A receptor and serotonin transporter binding in the human brain measured by PET. Neuroimage. 39: 1408-19. PMID 18036835 DOI: 10.1016/J.Neuroimage.2007.10.016 |
0.327 |
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| 2008 |
Takano A, Halldin C, Varrone A, Karlsson P, Sjöholm N, Stubbs JB, Schou M, Airaksinen AJ, Tauscher J, Gulyás B. Biodistribution and radiation dosimetry of the norepinephrine transporter radioligand (S,S)-[18F]FMeNER-D2: a human whole-body PET study. European Journal of Nuclear Medicine and Molecular Imaging. 35: 630-6. PMID 18000665 DOI: 10.1007/S00259-007-0622-Z |
0.616 |
|
| 2008 |
Takano A, Gulyás B, Varrone A, Karlsson P, Schou M, Airaksinen AJ, Vandenhende F, Tauscher J, Halldin C. Imaging the norepinephrine transporter with positron emission tomography: initial human studies with (S,S)-[18F]FMeNER-D2. European Journal of Nuclear Medicine and Molecular Imaging. 35: 153-7. PMID 17909794 DOI: 10.1007/S00259-007-0598-8 |
0.651 |
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| 2008 |
Varrone A, Schou M, Steiger C, Takano A, Finnema S, Guilloteau D, Gulyás B, Halldin C. Autoradiography and in vivo evaluation in cynomolgus monkey of [18F]FE-PE2I, a new dopamine transporter PET radioligand Neuroimage. 41. DOI: 10.1016/J.Neuroimage.2008.04.112 |
0.428 |
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| 2008 |
Varnäs K, Nyberg S, Halldin C, Varrone A, Takano A, Karlsson P, McCarthy D, Smith M, Pierson ME, Söderström J, Farde L. Quantitative analyses of [11C]AZ10419369 binding to 5-HT1B receptors in the human brain Neuroimage. 41. DOI: 10.1016/J.Neuroimage.2008.04.073 |
0.382 |
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| 2008 |
Takano A, Varrone A, Gulyás B, Karlsson P, Tauscher J, Halldin C. Mapping of the norepinephrine transporter in man using PET with (S,S)-[18F]FMeNER-D2 Neuroimage. 41: T103. DOI: 10.1016/J.Neuroimage.2008.04.072 |
0.583 |
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| 2008 |
Varrone A, Sjoholm N, Gulyas B, Halldin C, Farde L. Advancement in PET quantification using 3D-OP-OSEM PSF reconstruction with the HRRT Neuroimage. 41: T85. DOI: 10.1016/J.Neuroimage.2008.04.054 |
0.556 |
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| 2008 |
Odano I, Sakaguchi K, Hosoya T, Varrone A, Savic I, Halldin C, Farde L. Automated system for parametric image analysis in neuroreceptor binding studies with PET Neuroimage. 41: T77. DOI: 10.1016/J.Neuroimage.2008.04.047 |
0.426 |
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| 2006 |
Seneca N, Gulyás B, Varrone A, Schou M, Airaksinen A, Tauscher J, Vandenhende F, Kielbasa W, Farde L, Innis RB, Halldin C. Atomoxetine occupies the norepinephrine transporter in a dose-dependent fashion: a PET study in nonhuman primate brain using (S,S)-[18F]FMeNER-D2. Psychopharmacology. 188: 119-27. PMID 16896954 DOI: 10.1007/s00213-006-0483-3 |
0.595 |
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| 2006 |
Salvatore E, Varrone A, Sansone V, Nolano M, Bruni AC, De Rosa A, Santoro L, Pappatà S, Filla A, De Michele G. Characterization of nigrostriatal dysfunction in spinocerebellar ataxia 17. Movement Disorders : Official Journal of the Movement Disorder Society. 21: 872-5. PMID 16532453 DOI: 10.1002/Mds.20827 |
0.321 |
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| 2006 |
Varrone A, Sansone V, Pellecchia M, Amboni M, Vitale C, Salvatore E, De Michele G, Pappatà S, Barone P, Salvatore M. Imaging of the progression of nigrostriatal deficit in early-onset parkin disease with [123I]FP-CIT SPECT Neuroimage. 31: T158. DOI: 10.1016/J.Neuroimage.2006.04.141 |
0.301 |
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| 2006 |
Schou M, Pike VW, Varrone A, Gulyás B, Farde L, Halldin C. Synthesis and PET evaluation of (R)-[S-methyl-11C] thionisoxetine, a candidate radioligand for imaging brain norepinephrine transporters Journal of Labelled Compounds and Radiopharmaceuticals. 49: 1007-1019. DOI: 10.1002/Jlcr.1128 |
0.572 |
|
| 1998 |
Acampa W, Cuocolo A, Sullo P, Varrone A, Nicolai E, Pace L, Petretta M, Salvatore M. Direct comparison of technetium 99m-sestamibi and technetium 99m-tetrofosmin cardiac single photon emission computed tomography in patients with coronary artery disease. Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology. 5: 265-74. PMID 9669581 DOI: 10.1016/S1071-3581(98)90128-3 |
0.3 |
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