Vito Quaranta - Publications

Affiliations: 
Scripps Research Institute, La Jolla, La Jolla, CA, United States 
Area:
Cell Biology, Molecular Biology, Biochemistry

130 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Poirier JT, George J, Owonikoko TK, Berns A, Brambilla E, Byers LA, Carbone D, Chen HJ, Christensen CL, Dive C, Farago AF, Govindan R, Hann C, Hellmann MD, Horn L, ... ... Quaranta V, et al. New approaches to small cell lung cancer therapy : from the laboratory to the clinic. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 32018053 DOI: 10.1016/J.Jtho.2020.01.016  0.309
2019 Wooten DJ, Groves SM, Tyson DR, Liu Q, Lim JS, Albert R, Lopez CF, Sage J, Quaranta V. Systems-level network modeling of Small Cell Lung Cancer subtypes identifies master regulators and destabilizers. Plos Computational Biology. 15: e1007343. PMID 31671086 DOI: 10.1371/Journal.Pcbi.1007343  0.337
2019 McKenna MT, Weis JA, Quaranta V, Yankeelov TE. Leveraging Mathematical Modeling to Quantify Pharmacokinetic and Pharmacodynamic Pathways: Equivalent Dose Metric. Frontiers in Physiology. 10: 616. PMID 31178753 DOI: 10.3389/Fphys.2019.00616  0.306
2019 Rudin CM, Poirier JT, Byers LA, Dive C, Dowlati A, George J, Heymach JV, Johnson JE, Lehman JM, MacPherson D, Massion PP, Minna JD, Oliver TG, Quaranta V, Sage J, et al. Author Correction: Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data. Nature Reviews. Cancer. PMID 31175338 DOI: 10.1038/S41568-019-0164-2  0.316
2019 Rudin CM, Poirier JT, Byers LA, Dive C, Dowlati A, George J, Heymach JV, Johnson JE, Lehman JM, MacPherson D, Massion PP, Minna JD, Oliver TG, Quaranta V, Sage J, et al. Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data. Nature Reviews. Cancer. PMID 30926931 DOI: 10.1038/S41568-019-0133-9  0.357
2019 Paudel BB, Quaranta V. Metabolic plasticity meets gene regulation. Proceedings of the National Academy of Sciences of the United States of America. PMID 30737291 DOI: 10.1073/Pnas.1900169116  0.325
2019 Paudel BB, Harris LA, Hardeman KN, Hayford CE, Meyer CT, Abugable AA, Tyson DR, Fessel JP, Quaranta V. Abstract 2894: Overcoming intrinsic resistance toBRAF-inhibitors by modulating redox balance inBRAF-mutated melanoma cells Cancer Research. 79: 2894-2894. DOI: 10.1158/1538-7445.Am2019-2894  0.388
2018 Paudel BB, Harris LA, Hardeman KN, Abugable AA, Hayford CE, Tyson DR, Quaranta V. A Nonquiescent "Idling" Population State in Drug-Treated, BRAF-Mutated Melanoma. Biophysical Journal. 114: 1499-1511. PMID 29590606 DOI: 10.1016/J.Bpj.2018.01.016  0.304
2018 McKenna MT, Weis JA, Quaranta V, Yankeelov TE. Variable Cell Line Pharmacokinetics Contribute to Non-Linear Treatment Response in Heterogeneous Cell Populations. Annals of Biomedical Engineering. PMID 29484528 DOI: 10.1007/S10439-018-2001-2  0.338
2018 Jones ZW, Leander R, Quaranta V, Harris LA, Tyson DR. A drift-diffusion checkpoint model predicts a highly variable and growth-factor-sensitive portion of the cell cycle G1 phase. Plos One. 13: e0192087. PMID 29432467 DOI: 10.1371/Journal.Pone.0192087  0.348
2017 McKenna MT, Weis JA, Barnes SL, Tyson DR, Miga MI, Quaranta V, Yankeelov TE. A Predictive Mathematical Modeling Approach for the Study of Doxorubicin Treatment in Triple Negative Breast Cancer. Scientific Reports. 7: 5725. PMID 28720897 DOI: 10.1038/S41598-017-05902-Z  0.329
2017 Wooten DJ, Quaranta V. Mathematical Models of Cell Phenotype Regulation and Reprogramming: Make Cancer Cells Sensitive Again! Biochimica Et Biophysica Acta. PMID 28396217 DOI: 10.1016/J.Bbcan.2017.04.001  0.381
2017 Hardeman KN, Peng C, Paudel BB, Meyer CT, Luong T, Tyson DR, Young JD, Quaranta V, Fessel JP. Dependence On Glycolysis Sensitizes BRAF-mutated Melanomas For Increased Response To Targeted BRAF Inhibition. Scientific Reports. 7: 42604. PMID 28205616 DOI: 10.1038/Srep42604  0.307
2017 McKenna MT, Barnes SL, Weis JA, Searfoss AM, Tyson DR, Rericha EC, Miga MI, Quaranta V, Yankeelov TE. Abstract A14: Predicting the response of triple negative breast cancer to doxorubicin Cancer Research. 77. DOI: 10.1158/1538-7445.Epso16-A14  0.332
2016 Viquez OM, Yazlovitskaya EM, Tu T, Mernaugh G, Secades P, McKee KK, Quaranta V, Yurchenco P, Gewin LC, Sonnenberg A, Pozzi A, Zent R. Integrin alpha6 maintains the structural integrity of the kidney collecting system. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 28043890 DOI: 10.1016/J.Matbio.2016.12.003  0.315
2016 Franco OE, Tyson DR, Konvinse KC, Udyavar AR, Estrada L, Quaranta V, Crawford SE, Hayward SW. Altered TGF-α/β signaling drives cooperation between breast cancer cell populations. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 27383183 DOI: 10.1096/Fj.201500187Rr  0.364
2016 Harris LA, Frick PL, Garbett SP, Hardeman KN, Paudel BB, Lopez CF, Quaranta V, Tyson DR. An unbiased metric of antiproliferative drug effect in vitro. Nature Methods. PMID 27135974 DOI: 10.1038/Nmeth.3852  0.304
2016 Hardeman KN, Peng C, Paudel B, Tyson D, Young JD, Quaranta V, Fessel JP. Abstract A43: BRAF-mutated melanomas exhibit distinct metabolic programs that may determine therapeutic response Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Metca15-A43  0.349
2016 McKenna MT, Barnes SL, Searfoss A, Tyson DR, Rericha E, Quaranta V, Yankeelov TE. Abstract 776: Multiscale treatment response model for triple-negative breast cancer linking drug pharmacokinetics to tumor cell population dynamics Cancer Research. 76: 776-776. DOI: 10.1158/1538-7445.Am2016-776  0.361
2015 Yazlovitskaya EM, Tseng HY, Viquez O, Tu T, Mernaugh G, McKee KK, Riggins K, Quaranta V, Pathak A, Carter BD, Yurchenco P, Sonnenberg A, Böttcher RT, Pozzi A, Zent R. Integrin α3β1 regulates kidney collecting duct development via TRAF6-dependent K63-linked polyubiquitination of Akt. Molecular Biology of the Cell. 26: 1857-74. PMID 25808491 DOI: 10.1091/Mbc.E14-07-1203  0.35
2015 Broussard JA, Diggins NL, Hummel S, Georgescu W, Quaranta V, Webb DJ. Automated analysis of cell-matrix adhesions in 2D and 3D environments. Scientific Reports. 5: 8124. PMID 25630460 DOI: 10.1038/Srep08124  0.305
2015 Frick PL, Paudel BB, Tyson DR, Quaranta V. Quantifying heterogeneity and dynamics of clonal fitness in response to perturbation. Journal of Cellular Physiology. 230: 1403-12. PMID 25600161 DOI: 10.1002/Jcp.24888  0.324
2015 Jameson KL, Frick PL, Tyson DR, Yankeelov TE, Quaranta V. Abstract 3747: Identification of NSCLC biomarkers underlying quantifiable drug-induced clonal fitness Cancer Research. 75: 3747-3747. DOI: 10.1158/1538-7445.Am2015-3747  0.361
2014 Leander R, Allen EJ, Garbett SP, Tyson DR, Quaranta V. Derivation and experimental comparison of cell-division probability densities. Journal of Theoretical Biology. 359: 129-35. PMID 24931675 DOI: 10.1016/J.Jtbi.2014.06.004  0.355
2014 Onishko HM, Zhao J, Jameson KL, Frick PL, Tyson DR, Quaranta V, Yankeelov TE, Rericha EC. Abstract 1845: Sensitivity of PC9 cells to erlotinib is affected by extracellular matrix Cancer Research. 74: 1845-1845. DOI: 10.1158/1538-7445.Am2014-1845  0.431
2014 Udyavar AR, Hoeksema M, Diggins K, Irish J, Massion PP, Quaranta V. Abstract B27: Phenotypic plasticity and heterogeneity in small cell lung cancer (SCLC): Novel molecular subtypes and potential for targeted therapy. Clinical Cancer Research. 20: B27-B27. DOI: 10.1158/1078-0432.14Aacriaslc-B27  0.393
2013 Tyson DR, Quaranta V. Beyond genetics in personalized cancer treatment: assessing dynamics and heterogeneity of tumor responses. Personalized Medicine. 10: 221-225. PMID 24696699 DOI: 10.2217/Pme.13.6  0.354
2013 Udyavar AR, Hoeksema MD, Clark JE, Zou Y, Tang Z, Li Z, Li M, Chen H, Statnikov A, Shyr Y, Liebler DC, Field J, Eisenberg R, Estrada L, Massion PP, ... Quaranta V, et al. Co-expression network analysis identifies Spleen Tyrosine Kinase (SYK) as a candidate oncogenic driver in a subset of small-cell lung cancer. Bmc Systems Biology. 7: S1. PMID 24564859 DOI: 10.1186/1752-0509-7-S5-S1  0.327
2013 Yankeelov TE, Atuegwu N, Hormuth D, Weis JA, Barnes SL, Miga MI, Rericha EC, Quaranta V. Clinically relevant modeling of tumor growth and treatment response. Science Translational Medicine. 5: 187ps9. PMID 23720579 DOI: 10.1126/Scitranslmed.3005686  0.306
2013 Udyavar AR, Hoeksema MD, Clark J, Zou Y, Li M, Chen C(, Eisenberg R, Statnikov A, Liebler DC, Field J, Shyr Y, Estrada L, Quaranta V, Massion PP. Abstract 5216: Gene co-expression network analysis of small cell lung cancer (SCLC) identifies new subclasses and novel therapeutic targets including Src family kinase Fyn and Spleen Tyrosine Kinase Syk. Cancer Research. 73: 5216-5216. DOI: 10.1158/1538-7445.Am2013-5216  0.36
2013 Frick PL, Tyson DR, Garbett SP, Lopez CF, Jones ZW, Quaranta V. Abstract 4626: Quantifying erlotinib response variability in EGFR-addicted cells. Cancer Research. 73: 4626-4626. DOI: 10.1158/1538-7445.Am2013-4626  0.374
2013 Tyson DR, Peng C, Hardeman KN, Paudel B, Quaranta V. Abstract 3403: A stochastically arising subpopulation of B-RafV600E-expressing melanoma continues division in the presence of vemurafenib. Cancer Research. 73: 3403-3403. DOI: 10.1158/1538-7445.Am2013-3403  0.391
2012 Hoshino D, Jourquin J, Emmons SW, Miller T, Goldgof M, Costello K, Tyson DR, Brown B, Lu Y, Prasad NK, Zhang B, Mills GB, Yarbrough WG, Quaranta V, Seiki M, et al. Network analysis of the focal adhesion to invadopodia transition identifies a PI3K-PKCα invasive signaling axis. Science Signaling. 5: ra66. PMID 22969158 DOI: 10.1126/Scisignal.2002964  0.339
2012 Tyson DR, Garbett SP, Frick PL, Quaranta V. Fractional proliferation: a method to deconvolve cell population dynamics from single-cell data. Nature Methods. 9: 923-8. PMID 22886092 DOI: 10.1038/Nmeth.2138  0.384
2012 Gabriel P, Garbett SP, Quaranta V, Tyson DR, Webb GF. The contribution of age structure to cell population responses to targeted therapeutics. Journal of Theoretical Biology. 311: 19-27. PMID 22796330 DOI: 10.1016/J.Jtbi.2012.07.001  0.369
2012 Hoshino D, Koshikawa N, Suzuki T, Quaranta V, Weaver AM, Seiki M, Ichikawa K. Establishment and validation of computational model for MT1-MMP dependent ECM degradation and intervention strategies. Plos Computational Biology. 8: e1002479. PMID 22511862 DOI: 10.1371/Journal.Pcbi.1002479  0.306
2012 Rejniak KA, Quaranta V, Anderson AR. Computational investigation of intrinsic and extrinsic mechanisms underlying the formation of carcinoma. Mathematical Medicine and Biology : a Journal of the Ima. 29: 67-84. PMID 21106672 DOI: 10.1093/Imammb/Dqq021  0.366
2012 Blinov ML, Udyavar A, Yarbrough W, Wang J, Estrada L, Quaranta V. Multi-Network Modeling of Cancer Cell States Biophysical Journal. 102: 22a. DOI: 10.1016/J.Bpj.2011.11.148  0.353
2011 Hassanein M, Weidow B, Koehler E, Bakane N, Garbett S, Shyr Y, Quaranta V. Development of high-throughput quantitative assays for glucose uptake in cancer cell lines. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 13: 840-52. PMID 20809209 DOI: 10.1007/S11307-010-0399-5  0.342
2011 Tripathi M, Potdar AA, Yamashita H, Weidow B, Cummings PT, Kirchhofer D, Quaranta V. Laminin-332 cleavage by matriptase alters motility parameters of prostate cancer cells. The Prostate. 71: 184-96. PMID 20672321 DOI: 10.1002/Pros.21233  0.384
2011 Hardeman K, Tyson D, Quaranta V. PD01-08: Heterogeneity of Lapatinib Responses in HCC1954 HER2−Overexpressing Breast Cancer Cells Revealed by Single-Cell Automated Microscopy. Cancer Research. 71. DOI: 10.1158/0008-5472.Sabcs11-Pd01-08  0.368
2010 Rejniak KA, Wang SE, Bryce NS, Chang H, Parvin B, Jourquin J, Estrada L, Gray JW, Arteaga CL, Weaver AM, Quaranta V, Anderson AR. Linking changes in epithelial morphogenesis to cancer mutations using computational modeling. Plos Computational Biology. 6. PMID 20865159 DOI: 10.1371/Journal.Pcbi.1000900  0.402
2010 Yamashita H, Tripathi M, Jourquin J, Kam Y, Liu S, Weidow B, Quaranta V. Lysophosphatidic Acid Upregulates Laminin-332 Expression during A431 Cell Colony Dispersal. Journal of Oncology. 2010. PMID 20862207 DOI: 10.1155/2010/107075  0.37
2010 Ocak S, Yamashita H, Udyavar AR, Miller AN, Gonzalez AL, Zou Y, Jiang A, Yi Y, Shyr Y, Estrada L, Quaranta V, Massion PP. DNA copy number aberrations in small-cell lung cancer reveal activation of the focal adhesion pathway. Oncogene. 29: 6331-42. PMID 20802517 DOI: 10.1038/Onc.2010.362  0.362
2010 Riggins KS, Mernaugh G, Su Y, Quaranta V, Koshikawa N, Seiki M, Pozzi A, Zent R. MT1-MMP-mediated basement membrane remodeling modulates renal development. Experimental Cell Research. 316: 2993-3005. PMID 20727881 DOI: 10.1016/J.Yexcr.2010.08.003  0.301
2010 Gruver JS, Potdar AA, Jeon J, Sai J, Anderson B, Webb D, Richmond A, Quaranta V, Cummings PT, Chung CY. Bimodal analysis reveals a general scaling law governing nondirected and chemotactic cell motility. Biophysical Journal. 99: 367-76. PMID 20643054 DOI: 10.1016/J.Bpj.2010.03.073  0.354
2010 Quaranta V, Garbett SP. Not all noise is waste. Nature Methods. 7: 269-72. PMID 20354516 DOI: 10.1038/Nmeth0410-269  0.34
2010 Yamashita H, Tripathi M, Harris MP, Liu S, Weidow B, Zent R, Quaranta V. The role of a recombinant fragment of laminin-332 in integrin alpha3beta1-dependent cell binding, spreading and migration. Biomaterials. 31: 5110-21. PMID 20347131 DOI: 10.1016/J.Biomaterials.2010.03.003  0.362
2010 Yamashita H, Shang M, Tripathi M, Jourquin J, Georgescu W, Liu S, Weidow B, Quaranta V. Epitope mapping of function-blocking monoclonal antibody CM6 suggests a "weak" integrin binding site on the laminin-332 LG2 domain. Journal of Cellular Physiology. 223: 541-8. PMID 20301201 DOI: 10.1002/Jcp.22107  0.6
2010 Potdar AA, Jeon J, Weaver AM, Quaranta V, Cummings PT. Human mammary epithelial cells exhibit a bimodal correlated random walk pattern. Plos One. 5: e9636. PMID 20224792 DOI: 10.1371/Journal.Pone.0009636  0.31
2010 Jeon J, Quaranta V, Cummings PT. An off-lattice hybrid discrete-continuum model of tumor growth and invasion. Biophysical Journal. 98: 37-47. PMID 20074513 DOI: 10.1016/J.Bpj.2009.10.002  0.415
2010 Liu S, Yamashita H, Weidow B, Weaver AM, Quaranta V. Laminin-332-beta1 integrin interactions negatively regulate invadopodia. Journal of Cellular Physiology. 223: 134-42. PMID 20039268 DOI: 10.1002/Jcp.22018  0.415
2010 Kam Y, Rejniak KA, Zhao H, Estrella V, Anderson AR, Quaranta V, Torres-Roca JF. Abstract 2018: Systems biology modeling of cellular radiosensitivity: A heterogeneity signature in the clonogenic assay Cancer Research. 70: 2018-2018. DOI: 10.1158/1538-7445.Am10-2018  0.411
2009 Quaranta V, Tyson DR, Garbett SP, Weidow B, Harris MP, Georgescu W. Trait variability of cancer cells quantified by high-content automated microscopy of single cells. Methods in Enzymology. 467: 23-57. PMID 19897088 DOI: 10.1016/S0076-6879(09)67002-6  0.37
2009 Anderson AR, Hassanein M, Branch KM, Lu J, Lobdell NA, Maier J, Basanta D, Weidow B, Narasanna A, Arteaga CL, Reynolds AB, Quaranta V, Estrada L, Weaver AM. Microenvironmental independence associated with tumor progression. Cancer Research. 69: 8797-806. PMID 19887618 DOI: 10.1158/0008-5472.Can-09-0437  0.375
2009 Guess CM, Quaranta V. Defining the role of laminin-332 in carcinoma. Matrix Biology : Journal of the International Society For Matrix Biology. 28: 445-55. PMID 19686849 DOI: 10.1016/J.Matbio.2009.07.008  0.374
2009 Kam Y, Karperien A, Weidow B, Estrada L, Anderson AR, Quaranta V. Nest expansion assay: a cancer systems biology approach to in vitro invasion measurements. Bmc Research Notes. 2: 130. PMID 19594934 DOI: 10.1186/1756-0500-2-130  0.406
2009 Hinow P, Gerlee P, McCawley LJ, Quaranta V, Ciobanu M, Wang S, Graham JM, Ayati BP, Claridge J, Swanson KR, Loveless M, Anderson AR. A spatial model of tumor-host interaction: application of chemotherapy. Mathematical Biosciences and Engineering : Mbe. 6: 521-46. PMID 19566124 DOI: 10.3934/Mbe.2009.6.521  0.348
2009 Guess CM, Lafleur BJ, Weidow BL, Quaranta V. A decreased ratio of laminin-332 beta3 to gamma2 subunit mRNA is associated with poor prognosis in colon cancer. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 18: 1584-90. PMID 19383890 DOI: 10.1158/1055-9965.Epi-08-1027  0.318
2009 Wang SE, Xiang B, Zent R, Quaranta V, Pozzi A, Arteaga CL. Transforming growth factor beta induces clustering of HER2 and integrins by activating Src-focal adhesion kinase and receptor association to the cytoskeleton. Cancer Research. 69: 475-82. PMID 19147560 DOI: 10.1158/0008-5472.Can-08-2649  0.31
2009 Anderson AR, Rejniak KA, Gerlee P, Quaranta V. Microenvironment driven invasion: a multiscale multimodel investigation. Journal of Mathematical Biology. 58: 579-624. PMID 18839176 DOI: 10.1007/S00285-008-0210-2  0.377
2008 Harris MP, Kim E, Weidow B, Wikswo JP, Quaranta V. Migration of isogenic cell lines quantified by dynamic multivariate analysis of single-cell motility. Cell Adhesion & Migration. 2: 127-36. PMID 19271355 DOI: 10.4161/Cam.2.2.6482  0.381
2008 Tripathi M, Nandana S, Yamashita H, Ganesan R, Kirchhofer D, Quaranta V. Laminin-332 is a substrate for hepsin, a protease associated with prostate cancer progression. The Journal of Biological Chemistry. 283: 30576-84. PMID 18784072 DOI: 10.1074/Jbc.M802312200  0.324
2008 Kam Y, Guess C, Estrada L, Weidow B, Quaranta V. A novel circular invasion assay mimics in vivo invasive behavior of cancer cell lines and distinguishes single-cell motility in vitro. Bmc Cancer. 8: 198. PMID 18625060 DOI: 10.1186/1471-2407-8-198  0.374
2008 Quaranta V, Rejniak KA, Gerlee P, Anderson AR. Invasion emerges from cancer cell adaptation to competitive microenvironments: quantitative predictions from multiscale mathematical models. Seminars in Cancer Biology. 18: 338-48. PMID 18524624 DOI: 10.1016/J.Semcancer.2008.03.018  0.363
2007 Hu G, Quaranta V, Li D. Modeling of effects of nutrient gradients on cell proliferation in microfluidic bioreactor. Biotechnology Progress. 23: 1347-54. PMID 17935347 DOI: 10.1021/Bp070234N  0.346
2007 Anderson ARA, Rejniak KA, Gerlee P, Quaranta V. Modelling of cancer growth, evolution and invasion: Bridging scales and models Mathematical Modelling of Natural Phenomena. 2: 1-29. DOI: 10.1051/Mmnp:2007001  0.351
2006 Anderson AR, Weaver AM, Cummings PT, Quaranta V. Tumor morphology and phenotypic evolution driven by selective pressure from the microenvironment. Cell. 127: 905-15. PMID 17129778 DOI: 10.1016/J.Cell.2006.09.042  0.336
2006 Jourquin J, Yang N, Kam Y, Guess C, Quaranta V. Dispersal of epithelial cancer cell colonies by lysophosphatidic acid (LPA). Journal of Cellular Physiology. 206: 337-46. PMID 16110477 DOI: 10.1002/Jcp.20470  0.408
2005 Hintermann E, Yang N, O'Sullivan D, Higgins JM, Quaranta V. Integrin alpha6beta4-erbB2 complex inhibits haptotaxis by up-regulating E-cadherin cell-cell junctions in keratinocytes. The Journal of Biological Chemistry. 280: 8004-15. PMID 15579904 DOI: 10.1074/Jbc.M406301200  0.402
2005 Koshikawa N, Minegishi T, Sharabi A, Quaranta V, Seiki M. Membrane-type matrix metalloproteinase-1 (MT1-MMP) is a processing enzyme for human laminin gamma 2 chain. The Journal of Biological Chemistry. 280: 88-93. PMID 15525652 DOI: 10.1074/Jbc.M411824200  0.345
2004 Hintermann E, Quaranta V. Epithelial cell motility on laminin-5: regulation by matrix assembly, proteolysis, integrins and erbB receptors. Matrix Biology : Journal of the International Society For Matrix Biology. 23: 75-85. PMID 15246107 DOI: 10.1016/J.Matbio.2004.03.001  0.446
2004 Wang H, Fu W, Im JH, Zhou Z, Santoro SA, Iyer V, DiPersio CM, Yu QC, Quaranta V, Al-Mehdi A, Muschel RJ. Tumor cell alpha3beta1 integrin and vascular laminin-5 mediate pulmonary arrest and metastasis. The Journal of Cell Biology. 164: 935-41. PMID 15024036 DOI: 10.1083/Jcb.200309112  0.367
2004 Bilban M, Ghaffari-Tabrizi N, Hintermann E, Bauer S, Molzer S, Zoratti C, Malli R, Sharabi A, Hiden U, Graier W, Knöfler M, Andreae F, Wagner O, Quaranta V, Desoye G. Kisspeptin-10, a KiSS-1/metastin-derived decapeptide, is a physiological invasion inhibitor of primary human trophoblasts. Journal of Cell Science. 117: 1319-28. PMID 15020672 DOI: 10.1242/Jcs.00971  0.329
2004 Koshikawa N, Schenk S, Moeckel G, Sharabi A, Miyazaki K, Gardner H, Zent R, Quaranta V. Proteolytic processing of laminin-5 by MT1-MMP in tissues and its effects on epithelial cell morphology. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 364-6. PMID 14688206 DOI: 10.1096/Fj.03-0584Fje  0.305
2003 Quaranta V, Giannelli G. Cancer invasion: watch your neighbourhood! Tumori. 89: 343-8. PMID 14606634 DOI: 10.1177/030089160308900401  0.382
2003 Schenk S, Quaranta V. Tales from the crypt[ic] sites of the extracellular matrix. Trends in Cell Biology. 13: 366-75. PMID 12837607 DOI: 10.1016/S0962-8924(03)00129-6  0.326
2003 Hendrix MJ, Seftor EA, Kirschmann DA, Quaranta V, Seftor RE. Remodeling of the microenvironment by aggressive melanoma tumor cells. Annals of the New York Academy of Sciences. 995: 151-61. PMID 12814947 DOI: 10.1111/J.1749-6632.2003.Tb03218.X  0.433
2003 Schenk S, Hintermann E, Bilban M, Koshikawa N, Hojilla C, Khokha R, Quaranta V. Binding to EGF receptor of a laminin-5 EGF-like fragment liberated during MMP-dependent mammary gland involution. The Journal of Cell Biology. 161: 197-209. PMID 12695504 DOI: 10.1083/Jcb.200208145  0.34
2003 Pirilä E, Sharabi A, Salo T, Quaranta V, Tu H, Heljasvaara R, Koshikawa N, Sorsa T, Maisi P. Matrix metalloproteinases process the laminin-5 gamma 2-chain and regulate epithelial cell migration. Biochemical and Biophysical Research Communications. 303: 1012-7. PMID 12684035 DOI: 10.1016/S0006-291X(03)00452-2  0.341
2003 Gao C, Mao S, Ronca F, Zhuang S, Quaranta V, Wirsching P, Janda KD. De novo identification of tumor-specific internalizing human antibody-receptor pairs by phage-display methods. Journal of Immunological Methods. 274: 185-97. PMID 12609544 DOI: 10.1016/S0022-1759(02)00522-7  0.398
2002 Quaranta V. Motility cues in the tumor microenvironment. Differentiation; Research in Biological Diversity. 70: 590-8. PMID 12492500 DOI: 10.1046/J.1432-0436.2002.700912.X  0.346
2002 Hintermann E, Haake SK, Christen U, Sharabi A, Quaranta V. Discrete proteolysis of focal contact and adherens junction components in Porphyromonas gingivalis-infected oral keratinocytes: a strategy for cell adhesion and migration disabling. Infection and Immunity. 70: 5846-56. PMID 12228316 DOI: 10.1128/Iai.70.10.5846-5856.2002  0.375
2001 Zent R, Bush KT, Pohl ML, Quaranta V, Koshikawa N, Wang Z, Kreidberg JA, Sakurai H, Stuart RO, Nigám SK. Involvement of laminin binding integrins and laminin-5 in branching morphogenesis of the ureteric bud during kidney development Developmental Biology. 238: 289-302. PMID 11784011 DOI: 10.1006/Dbio.2001.0391  0.324
2001 Kiosses WB, Hahn KM, Giannelli G, Quaranta V. Characterization of morphological and cytoskeletal changes in MCF10A breast epithelial cells plated on laminin-5: comparison with breast cancer cell line MCF7. Cell Communication & Adhesion. 8: 29-44. PMID 11775027 DOI: 10.3109/15419060109080705  0.385
2001 Shang M, Koshikawa N, Schenk S, Quaranta V. The LG3 module of laminin-5 harbors a binding site for integrin alpha3beta1 that promotes cell adhesion, spreading, and migration. The Journal of Biological Chemistry. 276: 33045-53. PMID 11395486 DOI: 10.1074/Jbc.M100798200  0.625
2001 Hintermann E, Bilban M, Sharabi A, Quaranta V. Inhibitory role of α6β4-associated erbB-2 and phosphoinositide 3-kinase in keratinocyte haptotactic migration dependent on α3β1 integrin Journal of Cell Biology. 152: 465-478. PMID 11331299 DOI: 10.1083/Jcb.153.3.465  0.349
2001 Giannelli G, Bergamini C, Fransvea E, Marinosci F, Quaranta V, Antonaci S. Human hepatocellular carcinoma (HCC) cells require both α3β1 integrin and matrix metalloproteinases activity for migration and invasion Laboratory Investigation. 81: 613-627. PMID 11304581 DOI: 10.1038/Labinvest.3780270  0.34
2000 Plopper GE, Huff JL, Rust WL, Schwartz MA, Quaranta V. Antibody-induced activation of β1 integrin receptors stimulates cAMP-dependent migration of breast cells on laminin-5 Molecular Cell Biology Research Communications. 4: 129-135. PMID 11170844 DOI: 10.1006/Mcbr.2001.0267  0.359
2000 Cirulli V, Beattie GM, Klier G, Ellisman M, Ricordi C, Quaranta V, Frasier F, Ishii JK, Hayek A, Salomon DR. Expression and function of alpha(v)beta(3) and alpha(v)beta(5) integrins in the developing pancreas: roles in the adhesion and migration of putative endocrine progenitor cells. The Journal of Cell Biology. 150: 1445-60. PMID 10995448 DOI: 10.1083/Jcb.150.6.1445  0.365
2000 Quaranta V. Cell migration through extracellular matrix: Membrane-type metalloproteinases make the way Journal of Cell Biology. 149: 1167-1169. PMID 10851014 DOI: 10.1083/Jcb.149.6.1167  0.318
2000 Koshikawa N, Giannelli G, Cirulli V, Miyazaki K, Quaranta V. Role of cell surface metalloprotease MT1-MMP in epithelial cell migration over laminin-5 Journal of Cell Biology. 148: 615-624. PMID 10662785 DOI: 10.1083/Jcb.148.3.615  0.33
1999 Giannelli G, Pozzi A, Stetler-Stevenson WG, Gardner HA, Quaranta V. Expression of matrix metalloprotease-2-cleaved laminin-5 in breast remodeling stimulated by sex steroids. The American Journal of Pathology. 154: 1193-201. PMID 10233857 DOI: 10.1016/S0002-9440(10)65371-0  0.323
1999 Mullen LM, Richards DW, Quaranta V. Evidence that laminin-5 is a component of the tooth surface internal basal lamina, supporting epithelial cell adhesion. Journal of Periodontal Research. 34: 16-24. PMID 10086882 DOI: 10.1111/J.1600-0765.1999.Tb02217.X  0.337
1998 Plopper GE, Domanico SZ, Cirulli V, Kiosses WB, Quaranta V. Migration of breast epithelial cells on Laminin-5: Differential role of integrins in normal and transformed cell types Breast Cancer Research and Treatment. 51: 57-69. PMID 9877029 DOI: 10.1023/A:1006086218174  0.393
1998 Fitchmun MI, Falk-Marzillier J, Marshall E, Cruz G, Jones JCR, Quaranta V. Mode of adsorption and orientation of an extracellular matrix protein affect its cell-adhesion-promoting activity Analytical Biochemistry. 265: 1-7. PMID 9866700 DOI: 10.1006/Abio.1998.2877  0.371
1998 Falk-Marzillier J, Domanico SZ, Pelletier A, Mullen L, Quaranta V. Characterization of a tight molecular complex between integrin α6β4 and laminin-5 extracellular matrix Biochemical and Biophysical Research Communications. 251: 49-55. PMID 9790905 DOI: 10.1006/Bbrc.1998.9400  0.355
1998 Wong NC, Mueller BM, Barbas CF, Ruminski P, Quaranta V, Lin ECK, Smith JW. α(v) Integrins mediate adhesion and migration of breast carcinoma cell lines Clinical and Experimental Metastasis. 16: 50-61. PMID 9502077 DOI: 10.1023/A:1006512018609  0.372
1997 Domanico SZ, Pelletier AJ, Havran WL, Quaranta V. Integrin α6Aβ1 induces CD81-dependent cell motility without engaging the extracellular matrix migration substrate Molecular Biology of the Cell. 8: 2253-2265. PMID 9362067 DOI: 10.1091/Mbc.8.11.2253  0.424
1997 Giannelli G, Falk-Marzillier J, Schiraldi O, Stetler-Stevenson WG, Quaranta V. Induction of cell migration by matrix metalloprotease-2 cleavage of laminin-5 Science. 277: 225-228. PMID 9211848 DOI: 10.1126/Science.277.5323.225  0.383
1997 Tamura RN, Oda D, Quaranta V, Plopper G, Lambert R, Glaser S, Jones JCR. Coating of titanium alloy with soluble laminin-5 promotes cell attachment and hemidesmosome assembly in gingival epithelial cells: Potential application to dental implants Journal of Periodontal Research. 32: 287-294. PMID 9138194 DOI: 10.1111/J.1600-0765.1997.Tb00536.X  0.311
1996 Baker SE, DiPasquale AP, Stock EL, Quaranta V, Fitchmun M, Jones JCR. Morphogenetic effects of soluble laminin-5 on cultured epithelial cells and tissue explants Experimental Cell Research. 228: 262-270. PMID 8912719 DOI: 10.1006/Excr.1996.0325  0.395
1996 Zigrino P, Gaietta G, Zambonin-Zallone A, Pelletier AJ, Quaranta V. Evidence for a K+ channel requirement in spreading of rat basophilic leukemia cells on fibronectin-coated surfaces Biochemical and Biophysical Research Communications. 221: 51-58. PMID 8660342 DOI: 10.1006/Bbrc.1996.0543  0.304
1995 Tennenbaum T, Belanger AJ, Glick AB, Tamura R, Quaranta V, Yuspa SH. A splice variant of α6 integrin is associated with malignant conversion in mouse skin tumorigenesis Proceedings of the National Academy of Sciences of the United States of America. 92: 7041-7045. PMID 7624366 DOI: 10.1073/Pnas.92.15.7041  0.376
1995 Collo G, Domanico SZ, Klier G, Quaranta V. Gradient of integrin α6A distribution in the myocardium during early heart development Cell Adhesion and Communication. 3: 101-113. PMID 7583004 DOI: 10.3109/15419069509081280  0.325
1995 Hormia M, Falk-Marzillier J, Plopper G, Tamura RN, Jones JCR, Quaranta V. Rapid spreading and mature hemidesmosome formation in HaCaT keratinocytes induced by incubation with soluble laminin-5r Journal of Investigative Dermatology. 105: 557-561. PMID 7561158 DOI: 10.1111/1523-1747.Ep12323451  0.324
1995 Pelletier AJ, Kunicki T, Ruggeri ZM, Quaranta V. The activation state of the integrin αIIbβ3 affects outside-in signals leading to cell spreading and focal adhesion kinase phosphorylation Journal of Biological Chemistry. 270: 18133-18140. PMID 7543096 DOI: 10.1074/Jbc.270.30.18133  0.354
1993 Koukoulis GK, Virtanen I, Moll R, Quaranta V, Gould VE. Immunoloealization of integrins in the normal and neoplastic colonic epithelium Virchows Archiv B Cell Pathology Including Molecular Pathology. 63: 373-383. PMID 7686700 DOI: 10.1007/Bf02899286  0.35
1991 Tamura RN, Cooper HM, Collo G, Quaranta V. Cell type-specific integrin variants with alternative α chain cytoplasmic domains Proceedings of the National Academy of Sciences of the United States of America. 88: 10183-10187. PMID 1946438 DOI: 10.1073/Pnas.88.22.10183  0.344
1991 Jones JC, Kurpakus MA, Cooper HM, Quaranta V. A function for the integrin alpha 6 beta 4 in the hemidesmosome Cell Regulation. 2: 427-438. PMID 1883873 DOI: 10.1091/Mbc.2.6.427  0.361
1991 Cooper HM, Tamura RN, Quaranta V. The major laminin receptor of mouse embryonic stem cells is a novel isoform of the α6β1 integrin Journal of Cell Biology. 115: 843-850. PMID 1833411 DOI: 10.1083/Jcb.115.3.843  0.403
1991 de Curtis I, Quaranta V, Tamura RN, Reichardt LF. Laminin receptors in the retina: sequence analysis of the chick integrin alpha 6 subunit. Evidence for transcriptional and posttranslational regulation. The Journal of Cell Biology. 113: 405-16. PMID 1826298 DOI: 10.1083/Jcb.113.2.405  0.315
1991 Kurpakus MA, Quaranta V, Jones JCR. Surface relocation of alpha6beta4 integrins and assembly of hemidesmosomes in an in vitro model of wound healing Journal of Cell Biology. 115: 1737-1750. PMID 1757471 DOI: 10.1083/Jcb.115.6.1737  0.418
1991 Quaranta V, Jones JCR. The internal affairs of an integrin Trends in Cell Biology. 1: 2-4. DOI: 10.1016/0962-8924(91)90046-C  0.36
1991 Jones JCR, Kurpakus MA, Cooper HM, Quaranta V. A function for the integrin α6β4 in the hemidesmosome Molecular Biology of the Cell. 2: 427-438.  0.32
1990 De Luca M, Tamura RN, Kajiji S, Bondanza S, Rossino P, Cancedda R, Marchisio PC, Quaranta V. Polarized integrin mediates human keratinocyte adhesion to basal lamina. Proceedings of the National Academy of Sciences of the United States of America. 87: 6888-92. PMID 2395883 DOI: 10.1073/Pnas.87.17.6888  0.315
1990 MARCHISIO P, DELUCA M, BONDANZA S, CREMONA O, COOPER H, CANCEDDA R, QUARANTA V. Functional analysis and topography of integrins in human epithelial cells Cell Biology International Reports. 14: 17. DOI: 10.1016/0309-1651(90)90178-2  0.354
1989 Cheresh DA, Smith JW, Cooper HM, Quaranta V. A novel vitronectin receptor integrin (αvβx) is responsible for distinct adhesive properties of carcinoma cells Cell. 57: 59-69. PMID 2467745 DOI: 10.1016/0092-8674(89)90172-4  0.397
1987 Posillico JT, Srikanta S, Eisenbarth G, Quaranta V, Kajiji S, Brown EM. Binding of monoclonal antibody (4F2) to its cell surface antigen on dispersed adenomatous parathyroid cells raises cytosolic calcium and inhibits parathyroid hormone secretion Journal of Clinical Endocrinology and Metabolism. 64: 43-50. PMID 3782435 DOI: 10.1210/Jcem-64-1-43  0.317
1987 Posillico JT, Wilson RE, Srikanta SS, Eisenbarth GS, Letarte M, Quackenbush EJ, Quaranta V, Kajaji S, Brown EM. Monoclonal antibody-mediated modulation of parathyroid hormone secretion by dispersed parathyroid cells. Archives of Surgery (Chicago, Ill. : 1960). 122: 436-42. PMID 3551881 DOI: 10.1001/Archsurg.1987.01400160062009  0.347
1987 Bono C, Pereira MB, O'Sullivan DM, Quaranta V, Schwartz BD. The HLA-class II-associated chondroitin sulfate proteoglycan expressed by class II positive T and monocyte-like cell lines is larger than that expressed by EBV-transformed B-lymphoblastoid cell lines. Human Immunology. 18: 315-30. PMID 3032875 DOI: 10.1016/0198-8859(87)90078-4  0.345
1985 Nowell J, Quaranta V. Chloroquine affects biosynthesis of Ia molecules by inhibiting dissociation of invariant (γ) chains from α-β dimers in B cells Journal of Experimental Medicine. 162: 1371-1376. PMID 3930653 DOI: 10.1084/Jem.162.4.1371  0.301
1981 Natali PG, De Martino C, Marcellini M, Quaranta V, Ferrone S. Expression of Ia-like antigens on the vasculature of human kidney Clinical Immunology and Immunopathology. 20: 11-20. PMID 7021026 DOI: 10.1016/0090-1229(81)90157-4  0.308
1981 Natali PG, De Martino C, Quaranta V, Nicotra MR, Frezza F, Pellegrino MA, Ferrone S. Expression of Ia-like antigens in normal human nonlymphoid tissues Transplantation. 31. PMID 7015604 DOI: 10.1097/00007890-198101000-00017  0.357
1981 Natali PG, De Martino C, Quaranta V, Bigotti A, Pellegrino MA, Ferrone S. Changes in Ia-like antigen expression on malignant human cells. Immunogenetics. 12: 409-13. PMID 7009419 DOI: 10.1007/Bf01561680  0.304
1981 Natali PG, Cordiali-Fei P, Cavaliere R, Di Filippo F, Quaranta V, Pellegrino MA, Ferrone S. Ia-like antigens on freshly explanted human melanoma. Clinical Immunology and Immunopathology. 19: 250-9. PMID 6784988 DOI: 10.1016/0090-1229(81)90067-2  0.338
1981 Indiveri AK, Russo C, Quaranta V. Characterization of human null cells isolated from peripheral lymphocytes by a simultaneous double-rosettig procedure Scandinavian Journal of Immunology. 14: 225-231. PMID 6460312 DOI: 10.1111/J.1365-3083.1981.Tb00559.X  0.377
1981 Wilson BS, Glassy MC, Quaranta V, Ng AK, Ferrone S. Effect of tunicamycin on the assembly and antigenicity of HLA antigens: Analysis with monoclonal antibodies Scandinavian Journal of Immunology. 14: 201-205. PMID 6171878 DOI: 10.1111/J.1365-3083.1981.Tb00200.X  0.301
1980 Indiveri F, Ng AK, Russo C, Quaranta V, Pellegrino MA, Ferrone S. Isolation of Ia-like antigen-bearing cells from human peripheral lymphocytes through the use of a monoclonal antibody to framework determinants of Ia-like antigens Journal of Immunological Methods. 39: 343-354. PMID 6161968 DOI: 10.1016/0022-1759(80)90234-3  0.392
1979 McCabe RP, Quaranta V, Frugis L, Ferrone S, Reisfeld RA. A radioimmunometric antibody-binding assay for evaluation of xenoantisera to melanoma-associated antigens Journal of the National Cancer Institute. 62: 455-463. PMID 283276 DOI: 10.1093/Jnci/62.3.455  0.332
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