Leah E. Cowen, Ph.D. - Publications

2002 University of Toronto, Toronto, ON, Canada 
Microbiology Biology, Pathology

83 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Kim SH, Iyer KR, Pardeshi L, Muñoz JF, Robbins N, Cuomo CA, Wong KH, Cowen LE. Erratum for Kim et al., "Genetic Analysis of Candida auris Implicates Hsp90 in Morphogenesis and Azole Tolerance and Cdr1 in Azole Resistance". Mbio. 10. PMID 30890611 DOI: 10.1128/mBio.00346-19  0.72
2019 Guan G, Tao L, Yue H, Liang W, Gong J, Bing J, Zheng Q, Veri AO, Fan S, Robbins N, Cowen LE, Huang G. Environment-induced same-sex mating in the yeast Candida albicans through the Hsf1-Hsp90 pathway. Plos Biology. 17: e2006966. PMID 30865631 DOI: 10.1371/journal.pbio.2006966  0.72
2019 Kim SH, Iyer KR, Pardeshi L, Muñoz JF, Robbins N, Cuomo CA, Wong KH, Cowen LE. Genetic Analysis of Implicates Hsp90 in Morphogenesis and Azole Tolerance and Cdr1 in Azole Resistance. Mbio. 10. PMID 30696744 DOI: 10.1128/mBio.02529-18  0.72
2019 Whitesell L, Robbins N, Huang DS, McLellan CA, Shekhar-Guturja T, LeBlanc EV, Nation CS, Hui R, Hutchinson A, Collins C, Chatterjee S, Trilles R, Xie JL, Krysan DJ, Lindquist S, ... ... Cowen LE, et al. Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus. Nature Communications. 10: 402. PMID 30679438 DOI: 10.1038/s41467-018-08248-w  0.72
2019 Polvi EJ, Veri AO, Liu Z, Hossain S, Hyde S, Kim SH, Tebbji F, Sellam A, Todd RT, Xie JL, Lin ZY, Wong CJ, Shapiro RS, Whiteway M, Robbins N, ... ... Cowen LE, et al. Functional divergence of a global regulatory complex governing fungal filamentation. Plos Genetics. 15: e1007901. PMID 30615616 DOI: 10.1371/journal.pgen.1007901  0.96
2018 O'Meara TR, Cowen LE. Insights into the host-pathogen interaction: manipulation of macrophage pyroptosis. Microbial Cell (Graz, Austria). 5: 566-568. PMID 30533421 DOI: 10.15698/mic2018.12.662  0.44
2018 O'Meara TR, Duah K, Guo CX, Maxson ME, Gaudet RG, Koselny K, Wellington M, Powers ME, MacAlpine J, O'Meara MJ, Veri AO, Grinstein S, Noble SM, Krysan D, Gray-Owen SD, ... Cowen LE, et al. High-Throughput Screening Identifies Genes Required for Induction of Macrophage Pyroptosis. Mbio. 9. PMID 30131363 DOI: 10.1128/mBio.01581-18  0.44
2018 Dijck PV, Sjollema J, Cammue BP, Lagrou K, Berman J, d'Enfert C, Andes DR, Arendrup MC, Brakhage AA, Calderone R, Cantón E, Coenye T, Cos P, Cowen LE, Edgerton M, et al. Methodologies for and evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms. Microbial Cell (Graz, Austria). 5: 300-326. PMID 29992128 DOI: 10.15698/mic2018.07.638  0.8
2018 Caplan T, Polvi EJ, Xie JL, Buckhalter S, Leach MD, Robbins N, Cowen LE. Functional Genomic Screening Reveals Core Modulators of Echinocandin Stress Responses in Candida albicans. Cell Reports. 23: 2292-2298. PMID 29791841 DOI: 10.1016/j.celrep.2018.04.084  0.72
2018 Veri AO, Robbins N, Cowen LE. Regulation of the heat shock transcription factor Hsf1 in fungi: implications for temperature-dependent virulence traits. Fems Yeast Research. 18. PMID 29788061 DOI: 10.1093/femsyr/foy041  0.72
2018 Mount HO, Revie NM, Todd RT, Anstett K, Collins C, Costanzo M, Boone C, Robbins N, Selmecki A, Cowen LE. Global analysis of genetic circuitry and adaptive mechanisms enabling resistance to the azole antifungal drugs. Plos Genetics. 14: e1007319. PMID 29702647 DOI: 10.1371/journal.pgen.1007319  0.72
2018 Veri AO, Miao Z, Shapiro RS, Tebbji F, O'Meara TR, Kim SH, Colazo J, Tan K, Vyas VK, Whiteway M, Robbins N, Wong KH, Cowen LE. Tuning Hsf1 levels drives distinct fungal morphogenetic programs with depletion impairing Hsp90 function and overexpression expanding the target space. Plos Genetics. 14: e1007270. PMID 29590106 DOI: 10.1371/journal.pgen.1007270  0.96
2018 Maxson ME, Naj X, O'Meara TR, Plumb JD, Cowen LE, Grinstein S. Integrin-based diffusion barrier separates membrane domains enabling formation of microbiostatic frustrated phagosomes. Elife. 7. PMID 29553370 DOI: 10.7554/eLife.34798  0.44
2018 Revie NM, Iyer KR, Robbins N, Cowen LE. Antifungal drug resistance: evolution, mechanisms and impact. Current Opinion in Microbiology. 45: 70-76. PMID 29547801 DOI: 10.1016/j.mib.2018.02.005  0.72
2017 Xie JL, Bohovych I, Wong EOY, Lambert JP, Gingras AC, Khalimonchuk O, Cowen LE, Leach MD. Ydj1 governs fungal morphogenesis and stress response, and facilitates mitochondrial protein import via Mas1 and Mas2. Microbial Cell (Graz, Austria). 4: 342-361. PMID 29082232 DOI: 10.15698/mic2017.10.594  0.64
2017 Xie JL, Qin L, Miao Z, Grys BT, Diaz JC, Ting K, Krieger JR, Tong J, Tan K, Leach MD, Ketela T, Moran MF, Krysan DJ, Boone C, Andrews BJ, ... ... Cowen LE, et al. The Candida albicans transcription factor Cas5 couples stress responses, drug resistance and cell cycle regulation. Nature Communications. 8: 499. PMID 28894103 DOI: 10.1038/s41467-017-00547-y  0.72
2017 Robbins N, Caplan T, Cowen LE. Molecular Evolution of Antifungal Drug Resistance. Annual Review of Microbiology. 71: 753-775. PMID 28886681 DOI: 10.1146/annurev-micro-030117-020345  0.72
2017 O'Meara TR, Robbins N, Cowen LE. The Hsp90 Chaperone Network Modulates Candida Virulence Traits. Trends in Microbiology. PMID 28549824 DOI: 10.1016/j.tim.2017.05.003  0.72
2017 Xie JL, O'Meara TR, Polvi EJ, Robbins N, Cowen LE. Staurosporine Induces Filamentation in the Human Fungal Pathogen Candida albicans via Signaling through Cyr1 and Protein Kinase A. Msphere. 2. PMID 28261668 DOI: 10.1128/mSphere.00056-17  0.72
2016 Lee JA, Robbins N, Xie JL, Ketela T, Cowen LE. Functional Genomic Analysis of Candida albicans Adherence Reveals a Key Role for the Arp2/3 Complex in Cell Wall Remodelling and Biofilm Formation. Plos Genetics. 12: e1006452. PMID 27870871 DOI: 10.1371/journal.pgen.1006452  0.72
2016 Li X, Robbins N, O'Meara TR, Cowen LE. Extensive Functional Redundancy in the Regulation of Candida albicans Drug Resistance and Morphogenesis by Lysine Deacetylases Hos2, Hda1, Rpd3, and Rpd31. Molecular Microbiology. PMID 27868254 DOI: 10.1111/mmi.13578  0.72
2016 Leach MD, Kim T, DiGregorio S, Collins C, Zhang Z, Duennwald ML, Cowen LE. Candida albicans Is Resistant to Polyglutamine Aggregation and Toxicity. G3 (Bethesda, Md.). PMID 27807047 DOI: 10.1534/g3.116.035675  0.64
2016 Xie JL, Grahl N, Sless T, Leach MD, Kim SH, Hogan DA, Robbins N, Cowen LE. Signaling through Lrg1, Rho1 and Pkc1 Governs Candida albicans Morphogenesis in Response to Diverse Cues. Plos Genetics. 12: e1006405. PMID 27788136 DOI: 10.1371/journal.pgen.1006405  0.72
2016 Robbins N, Wright GD, Cowen LE. Antifungal Drugs: The Current Armamentarium and Development of New Agents. Microbiology Spectrum. 4. PMID 27763259 DOI: 10.1128/microbiolspec.FUNK-0002-2016  0.72
2016 Shekhar-Guturja T, Tebung WA, Mount H, Liu N, Köhler JR, Whiteway M, Cowen LE. Beauvericin Potentiates Azole Activity via Inhibition of Multidrug Efflux, Blocks C. albicans Morphogenesis, and is Effluxed via Yor1 and Circuitry Controlled by Zcf29. Antimicrobial Agents and Chemotherapy. PMID 27736764 DOI: 10.1128/AAC.01959-16  0.56
2016 Polvi EJ, Averette AF, Lee SC, Kim T, Bahn YS, Veri AO, Robbins N, Heitman J, Cowen LE. Metal Chelation as a Powerful Strategy to Probe Cellular Circuitry Governing Fungal Drug Resistance and Morphogenesis. Plos Genetics. 12: e1006350. PMID 27695031 DOI: 10.1371/journal.pgen.1006350  0.72
2016 Shekhar-Guturja T, Gunaherath GM, Wijeratne EM, Lambert JP, Averette AF, Lee SC, Kim T, Bahn YS, Tripodi F, Ammar R, Döhl K, Niewola-Staszkowska K, Schmitt L, Loewith RJ, Roth FP, ... ... Cowen LE, et al. Dual action antifungal small molecule modulates multidrug efflux and TOR signaling. Nature Chemical Biology. PMID 27571477 DOI: 10.1038/nchembio.2165  0.32
2016 O'Meara TR, Veri AO, Polvi EJ, Li X, Valaei SF, Diezmann S, Cowen LE. Mapping the Hsp90 Genetic Network Reveals Ergosterol Biosynthesis and Phosphatidylinositol-4-Kinase Signaling as Core Circuitry Governing Cellular Stress. Plos Genetics. 12: e1006142. PMID 27341673 DOI: 10.1371/journal.pgen.1006142  0.64
2016 Leach MD, Farrer RA, Tan K, Miao Z, Walker LA, Cuomo CA, Wheeler RT, Brown AJ, Wong KH, Cowen LE. Hsf1 and Hsp90 orchestrate temperature-dependent global transcriptional remodelling and chromatin architecture in Candida albicans. Nature Communications. 7: 11704. PMID 27226156 DOI: 10.1038/ncomms11704  1
2015 Hill JA, Cowen LE. Using combination therapy to thwart drug resistance. Future Microbiology. 10: 1719-26. PMID 26597425 DOI: 10.2217/fmb.15.68  1
2015 Kim SH, Clark ST, Surendra A, Copeland JK, Wang PW, Ammar R, Collins C, Tullis DE, Nislow C, Hwang DM, Guttman DS, Cowen LE. Global Analysis of the Fungal Microbiome in Cystic Fibrosis Patients Reveals Loss of Function of the Transcriptional Repressor Nrg1 as a Mechanism of Pathogen Adaptation. Plos Pathogens. 11: e1005308. PMID 26588216 DOI: 10.1371/journal.ppat.1005308  0.36
2015 Diezmann S, Leach MD, Cowen LE. Functional Divergence of Hsp90 Genetic Interactions in Biofilm and Planktonic Cellular States. Plos One. 10: e0137947. PMID 26367740 DOI: 10.1371/journal.pone.0137947  1
2015 O'Meara TR, Veri AO, Ketela T, Jiang B, Roemer T, Cowen LE. Global analysis of fungal morphology exposes mechanisms of host cell escape. Nature Communications. 6: 6741. PMID 25824284 DOI: 10.1038/ncomms7741  1
2015 Polvi EJ, Li X, O'Meara TR, Leach MD, Cowen LE. Opportunistic yeast pathogens: reservoirs, virulence mechanisms, and therapeutic strategies. Cellular and Molecular Life Sciences : Cmls. 72: 2261-87. PMID 25700837 DOI: 10.1007/s00018-015-1860-z  1
2015 Hill JA, O'Meara TR, Cowen LE. Fitness Trade-Offs Associated with the Evolution of Resistance to Antifungal Drug Combinations. Cell Reports. PMID 25660029 DOI: 10.1016/j.celrep.2015.01.009  1
2015 Cowen LE, Sanglard D, Howard SJ, Rogers PD, Perlin DS. Mechanisms of Antifungal Drug Resistance. Cold Spring Harbor Perspectives in Medicine. 5: a019752. PMID 25384768 DOI: 10.1101/cshperspect.a019752  1
2014 Leach MD, Cowen LE. Membrane fluidity and temperature sensing are coupled via circuitry comprised of Ole1, Rsp5, and Hsf1 in Candida albicans. Eukaryotic Cell. 13: 1077-84. PMID 24951438 DOI: 10.1128/EC.00138-14  1
2014 Xie JL, Polvi EJ, Shekhar-Guturja T, Cowen LE. Elucidating drug resistance in human fungal pathogens. Future Microbiology. 9: 523-42. PMID 24810351 DOI: 10.2217/fmb.14.18  1
2014 Veri A, Cowen LE. Progress and prospects for targeting Hsp90 to treat fungal infections. Parasitology. 141: 1127-37. PMID 24560124 DOI: 10.1017/S0031182013002072  1
2014 O'Meara TR, Cowen LE. Hsp90-dependent regulatory circuitry controlling temperature-dependent fungal development and virulence. Cellular Microbiology. 16: 473-81. PMID 24438186 DOI: 10.1111/cmi.12266  1
2014 Leach MD, Cowen LE. To sense or die: Mechanisms of temperature sensing in fungal pathogens Current Fungal Infection Reports. 8: 185-191. DOI: 10.1007/s12281-014-0182-1  1
2013 Hill JA, Ammar R, Torti D, Nislow C, Cowen LE. Genetic and genomic architecture of the evolution of resistance to antifungal drug combinations. Plos Genetics. 9: e1003390. PMID 23593013 DOI: 10.1371/journal.pgen.1003390  1
2013 Cowen LE. The fungal Achilles' heel: targeting Hsp90 to cripple fungal pathogens. Current Opinion in Microbiology. 16: 377-84. PMID 23588026 DOI: 10.1016/j.mib.2013.03.005  1
2013 Leach MD, Cowen LE. Surviving the heat of the moment: a fungal pathogens perspective. Plos Pathogens. 9: e1003163. PMID 23505364 DOI: 10.1371/journal.ppat.1003163  1
2013 Hill JA, Hoot SJ, White TC, Cowen LE. Evolution of Drug Resistance in Fungi Evolution of Virulence in Eukaryotic Microbes. 143-167. DOI: 10.1002/9781118308165.ch8  1
2012 Leach MD, Budge S, Walker L, Munro C, Cowen LE, Brown AJ. Hsp90 orchestrates transcriptional regulation by Hsf1 and cell wall remodelling by MAPK signalling during thermal adaptation in a pathogenic yeast. Plos Pathogens. 8: e1003069. PMID 23300438 DOI: 10.1371/journal.ppat.1003069  1
2012 Shapiro RS, Ryan O, Boone C, Cowen LE. Regulatory circuitry governing morphogenesis in Saccharomyces cerevisiae and Candida albicans. Cell Cycle (Georgetown, Tex.). 11: 4294-5. PMID 23095675 DOI: 10.4161/cc.22608  1
2012 Robbins N, Leach MD, Cowen LE. Lysine deacetylases Hda1 and Rpd3 regulate Hsp90 function thereby governing fungal drug resistance. Cell Reports. 2: 878-88. PMID 23041319 DOI: 10.1016/j.celrep.2012.08.035  1
2012 Shapiro RS, Cowen LE. Thermal control of microbial development and virulence: molecular mechanisms of microbial temperature sensing. Mbio. 3. PMID 23033469 DOI: 10.1128/mBio.00238-12  1
2012 Ryan O, Shapiro RS, Kurat CF, Mayhew D, Baryshnikova A, Chin B, Lin ZY, Cox MJ, Vizeacoumar F, Cheung D, Bahr S, Tsui K, Tebbji F, Sellam A, Istel F, ... ... Cowen LE, et al. Global gene deletion analysis exploring yeast filamentous growth. Science (New York, N.Y.). 337: 1353-6. PMID 22984072 DOI: 10.1126/science.1224339  1
2012 Leach MD, Klipp E, Cowen LE, Brown AJ. Fungal Hsp90: a biological transistor that tunes cellular outputs to thermal inputs. Nature Reviews. Microbiology. 10: 693-704. PMID 22976491 DOI: 10.1038/nrmicro2875  1
2012 Shapiro RS, Zaas AK, Betancourt-Quiroz M, Perfect JR, Cowen LE. The Hsp90 co-chaperone Sgt1 governs Candida albicans morphogenesis and drug resistance. Plos One. 7: e44734. PMID 22970302 DOI: 10.1371/journal.pone.0044734  1
2012 Singh-Babak SD, Shekhar T, Smith AM, Giaever G, Nislow C, Cowen LE. A novel calcineurin-independent activity of cyclosporin A in Saccharomyces cerevisiae. Molecular Biosystems. 8: 2575-84. PMID 22751784 DOI: 10.1039/c2mb25107h  1
2012 Shapiro RS, Cowen LE. Uncovering cellular circuitry controlling temperature-dependent fungal morphogenesis. Virulence. 3: 400-4. PMID 22722238 DOI: 10.4161/viru.20979  1
2012 Singh-Babak SD, Babak T, Diezmann S, Hill JA, Xie JL, Chen YL, Poutanen SM, Rennie RP, Heitman J, Cowen LE. Global analysis of the evolution and mechanism of echinocandin resistance in Candida glabrata. Plos Pathogens. 8: e1002718. PMID 22615574 DOI: 10.1371/journal.ppat.1002718  1
2012 Diezmann S, Michaut M, Shapiro RS, Bader GD, Cowen LE. Mapping the Hsp90 genetic interaction network in Candida albicans reveals environmental contingency and rewired circuitry. Plos Genetics. 8: e1002562. PMID 22438817 DOI: 10.1371/journal.pgen.1002562  1
2012 Shapiro RS, Sellam A, Tebbji F, Whiteway M, Nantel A, Cowen LE. Pho85, Pcl1, and Hms1 signaling governs Candida albicans morphogenesis induced by high temperature or Hsp90 compromise. Current Biology : Cb. 22: 461-70. PMID 22365851 DOI: 10.1016/j.cub.2012.01.062  1
2012 Senn H, Shapiro RS, Cowen LE. Cdc28 provides a molecular link between Hsp90, morphogenesis, and cell cycle progression in Candida albicans. Molecular Biology of the Cell. 23: 268-83. PMID 22090345 DOI: 10.1091/mbc.E11-08-0729  1
2011 Lissina E, Young B, Urbanus ML, Guan XL, Lowenson J, Hoon S, Baryshnikova A, Riezman I, Michaut M, Riezman H, Cowen LE, Wenk MR, Clarke SG, Giaever G, Nislow C. A systems biology approach reveals the role of a novel methyltransferase in response to chemical stress and lipid homeostasis. Plos Genetics. 7: e1002332. PMID 22028670 DOI: 10.1371/journal.pgen.1002332  1
2011 Robbins N, Uppuluri P, Nett J, Rajendran R, Ramage G, Lopez-Ribot JL, Andes D, Cowen LE. Hsp90 governs dispersion and drug resistance of fungal biofilms. Plos Pathogens. 7: e1002257. PMID 21931556 DOI: 10.1371/journal.ppat.1002257  1
2011 Shapiro RS, Robbins N, Cowen LE. Regulatory circuitry governing fungal development, drug resistance, and disease. Microbiology and Molecular Biology Reviews : Mmbr. 75: 213-67. PMID 21646428 DOI: 10.1128/MMBR.00045-10  1
2010 Shapiro RS, Cowen L. Coupling temperature sensing and development: Hsp90 regulates morphogenetic signalling in Candida albicans. Virulence. 1: 45-8. PMID 21178413 DOI: 10.4161/viru.1.1.10320  1
2010 LaFayette SL, Collins C, Zaas AK, Schell WA, Betancourt-Quiroz M, Gunatilaka AA, Perfect JR, Cowen LE. PKC signaling regulates drug resistance of the fungal pathogen Candida albicans via circuitry comprised of Mkc1, calcineurin, and Hsp90. Plos Pathogens. 6: e1001069. PMID 20865172 DOI: 10.1371/journal.ppat.1001069  1
2010 Robbins N, Collins C, Morhayim J, Cowen LE. Metabolic control of antifungal drug resistance. Fungal Genetics and Biology : Fg & B. 47: 81-93. PMID 19595784 DOI: 10.1016/j.fgb.2009.07.004  1
2009 Selmecki AM, Dulmage K, Cowen LE, Anderson JB, Berman J. Acquisition of aneuploidy provides increased fitness during the evolution of antifungal drug resistance. Plos Genetics. 5: e1000705. PMID 19876375 DOI: 10.1371/journal.pgen.1000705  1
2009 Cowen LE. Hsp90 orchestrates stress response signaling governing fungal drug resistance. Plos Pathogens. 5: e1000471. PMID 19714223 DOI: 10.1371/journal.ppat.1000471  1
2009 Singh SD, Robbins N, Zaas AK, Schell WA, Perfect JR, Cowen LE. Hsp90 governs echinocandin resistance in the pathogenic yeast Candida albicans via calcineurin. Plos Pathogens. 5: e1000532. PMID 19649312 DOI: 10.1371/journal.ppat.1000532  1
2009 Shapiro RS, Uppuluri P, Zaas AK, Collins C, Senn H, Perfect JR, Heitman J, Cowen LE. Hsp90 orchestrates temperature-dependent Candida albicans morphogenesis via Ras1-PKA signaling. Current Biology : Cb. 19: 621-9. PMID 19327993 DOI: 10.1016/j.cub.2009.03.017  1
2009 Cowen LE, Singh SD, Köhler JR, Collins C, Zaas AK, Schell WA, Aziz H, Mylonakis E, Perfect JR, Whitesell L, Lindquist S. Harnessing Hsp90 function as a powerful, broadly effective therapeutic strategy for fungal infectious disease Proceedings of the National Academy of Sciences of the United States of America. 106: 2818-2823. PMID 19196973 DOI: 10.1073/pnas.0813394106  1
2008 Shen J, Cowen LE, Griffin AM, Chan L, Köhler JR. The Candida albicans pescadillo homolog is required for normal hypha-to-yeast morphogenesis and yeast proliferation. Proceedings of the National Academy of Sciences of the United States of America. 105: 20918-23. PMID 19075239 DOI: 10.1073/pnas.0809147105  1
2008 Cowen LE, Steinbach WJ. Stress, drugs, and evolution: the role of cellular signaling in fungal drug resistance. Eukaryotic Cell. 7: 747-64. PMID 18375617 DOI: 10.1128/EC.00041-08  1
2008 Cowen LE. The evolution of fungal drug resistance: modulating the trajectory from genotype to phenotype. Nature Reviews. Microbiology. 6: 187-98. PMID 18246082 DOI: 10.1038/nrmicro1835  1
2006 Cowen LE, Carpenter AE, Matangkasombut O, Fink GR, Lindquist S. Genetic architecture of Hsp90-dependent drug resistance. Eukaryotic Cell. 5: 2184-8. PMID 17056742 DOI: 10.1128/EC.00274-06  1
2005 Cowen LE, Lindquist S. Hsp90 potentiates the rapid evolution of new traits: drug resistance in diverse fungi. Science (New York, N.Y.). 309: 2185-9. PMID 16195452 DOI: 10.1126/science.1118370  1
2003 Anderson JB, Sirjusingh C, Parsons AB, Boone C, Wickens C, Cowen LE, Kohn LM. Mode of selection and experimental evolution of antifungal drug resistance in Saccharomyces cerevisiae. Genetics. 163: 1287-98. PMID 12702675  1
2002 Cowen LE, Anderson JB, Kohn LM. Evolution of drug resistance in Candida albicans. Annual Review of Microbiology. 56: 139-65. PMID 12142485 DOI: 10.1146/annurev.micro.56.012302.160907  1
2002 Cowen LE, Nantel A, Whiteway MS, Thomas DY, Tessier DC, Kohn LM, Anderson JB. Population genomics of drug resistance in Candida albicans. Proceedings of the National Academy of Sciences of the United States of America. 99: 9284-9. PMID 12089321 DOI: 10.1073/pnas.102291099  1
2001 Cowen LE. Predicting the emergence of resistance to antifungal drugs Fems Microbiology Letters. 204: 1-7. PMID 11682169 DOI: 10.1016/S0378-1097(01)00362-7  1
2001 Cowen LE, Kohn LM, Anderson JB. Divergence in fitness and evolution of drug resistance in experimental populations of Candida albicans. Journal of Bacteriology. 183: 2971-8. PMID 11325923 DOI: 10.1128/JB.183.10.2971-2978.2001  1
2001 Luu LN, Cowen LE, Sirjusingh C, Kohn LM, Anderson JB. Multilocus genotyping indicates that the ability to invade the bloodstream is widespread among Candida albicans isolates. Journal of Clinical Microbiology. 39: 1657-60. PMID 11283111 DOI: 10.1128/JCM.39.4.1657-1660.2001  1
2001 Anderson JB, Wickens C, Khan M, Cowen LE, Federspiel N, Jones T, Kohn LM. Infrequent genetic exchange and recombination in the mitochondrial genome of Candida albicans. Journal of Bacteriology. 183: 865-72. PMID 11208783 DOI: 10.1128/JB.183.3.865-872.2001  1
2000 Cowen LE, Sanglard D, Calabrese D, Sirjusingh C, Anderson JB, Kohn LM. Evolution of drug resistance in experimental populations of Candida albicans. Journal of Bacteriology. 182: 1515-22. PMID 10692355 DOI: 10.1128/JB.182.6.1515-1522.2000  1
1999 Cowen LE, Sirjusingh C, Summerbell RC, Walmsley S, Richardson S, Kohn LM, Anderson JB. Multilocus genotypes and DNA fingerprints Do not predict variation in azole resistance among clinical isolates of Candida albicans. Antimicrobial Agents and Chemotherapy. 43: 2930-8. PMID 10582885  1
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