| Year |
Citation |
Score |
| 2024 |
Fallah S, Duncan D, Reichl KD, Smith MJ, Wang W, Porco JA, Brown LE, Whitesell L, Robbins N, Cowen LE. A chemical screen identifies structurally diverse metal chelators with activity against the fungal pathogen . Microbiology Spectrum. e0409523. PMID 38376363 DOI: 10.1128/spectrum.04095-23 |
0.327 |
|
| 2024 |
Puumala E, Fallah S, Robbins N, Cowen LE. Advancements and challenges in antifungal therapeutic development. Clinical Microbiology Reviews. e0014223. PMID 38294218 DOI: 10.1128/cmr.00142-23 |
0.651 |
|
| 2023 |
Case NT, Westman J, Hallett MT, Plumb J, Farheen A, Maxson ME, MacAlpine J, Liston SD, Hube B, Robbins N, Whitesell L, Grinstein S, Cowen LE. Respiration supports intraphagosomal filamentation and escape of from macrophages. Mbio. e0274523. PMID 38038475 DOI: 10.1128/mbio.02745-23 |
0.784 |
|
| 2023 |
MacAlpine J, Liu Z, Hossain S, Whitesell L, Robbins N, Cowen LE. DYRK-family kinases regulate morphogenesis and virulence through the Ras1/PKA pathway. Mbio. e0218323. PMID 38015416 DOI: 10.1128/mbio.02183-23 |
0.814 |
|
| 2023 |
Marquez L, Lee Y, Duncan D, Whitesell L, Cowen LE, Quave C. Potent Antifungal Activity of Penta--galloyl-β-d-Glucose against Drug-Resistant , , and Other Non- Species. Acs Infectious Diseases. PMID 37607350 DOI: 10.1021/acsinfecdis.3c00113 |
0.689 |
|
| 2023 |
Liu Z, Basso P, Hossain S, Liston SD, Robbins N, Whitesell L, Noble SM, Cowen LE. Multifactor transcriptional control of alternative oxidase induction integrates diverse environmental inputs to enable fungal virulence. Nature Communications. 14: 4528. PMID 37500616 DOI: 10.1038/s41467-023-40209-w |
0.807 |
|
| 2023 |
Robbins N, Cowen LE. Roles of Hsp90 in Candida albicans morphogenesis and virulence. Current Opinion in Microbiology. 75: 102351. PMID 37399670 DOI: 10.1016/j.mib.2023.102351 |
0.694 |
|
| 2023 |
Iyer KR, Li SC, Revie NM, Lou JW, Duncan D, Fallah S, Sanchez H, Skulska I, Ušaj MM, Safizadeh H, Larsen B, Wong C, Aman A, Kiyota T, Yoshimura M, ... ... Cowen LE, et al. Identification of triazenyl indoles as inhibitors of fungal fatty acid biosynthesis with broad-spectrum activity. Cell Chemical Biology. PMID 37369212 DOI: 10.1016/j.chembiol.2023.06.005 |
0.821 |
|
| 2023 |
Liu Z, MacAlpine J, Robbins N, Cowen LE. Construction of Candida albicans Strains with ATP-Analog-Sensitive Protein Kinase A and Hog1. Msphere. e0009523. PMID 37039635 DOI: 10.1128/msphere.00095-23 |
0.81 |
|
| 2023 |
Robbins N, Ketela T, Kim SH, Cowen LE. Chemical-Genetic Approaches for Exploring Mode of Action of Antifungal Compounds in the Fungal Pathogen Candida albicans. Methods in Molecular Biology (Clifton, N.J.). 2658: 145-165. PMID 37024700 DOI: 10.1007/978-1-0716-3155-3_10 |
0.676 |
|
| 2023 |
Lee Y, Hossain S, MacAlpine J, Robbins N, Cowen LE. Functional genomic analysis of protein kinases reveals modulators of morphogenesis in diverse environments. Iscience. 26: 106145. PMID 36879823 DOI: 10.1016/j.isci.2023.106145 |
0.803 |
|
| 2023 |
Lash E, Prudent V, Stogios PJ, Savchenko A, Noble SM, Robbins N, Cowen LE. Ent2 Governs Morphogenesis and Virulence in Part through Regulation of the Cdc42 Signaling Cascade in the Fungal Pathogen Candida albicans. Mbio. e0343422. PMID 36809010 DOI: 10.1128/mbio.03434-22 |
0.826 |
|
| 2022 |
Basso P, Dang EV, Urisman A, Cowen LE, Madhani HD, Noble SM. Deep tissue infection by an invasive human fungal pathogen requires lipid-based suppression of the IL-17 response. Cell Host & Microbe. 30: 1589-1601.e5. PMID 36323314 DOI: 10.1016/j.chom.2022.10.004 |
0.698 |
|
| 2022 |
Puumala E, Zaslaver O, Chen A, Duncan D, Fogal M, Shapiro RS, Mazhab-Jafari MT, Whitesell L, Montenegro-Burke JR, Robbins N, Cowen LE. The Trisubstituted Isoxazole MMV688766 Exerts Broad-Spectrum Activity against Drug-Resistant Fungal Pathogens through Inhibition of Lipid Homeostasis. Mbio. e0273022. PMID 36300931 DOI: 10.1128/mbio.02730-22 |
0.84 |
|
| 2022 |
Liston SD, Whitesell L, Kapoor M, Shaw KJ, Cowen LE. Calcineurin Inhibitors Synergize with Manogepix to Kill Diverse Human Fungal Pathogens. Journal of Fungi (Basel, Switzerland). 8. PMID 36294667 DOI: 10.3390/jof8101102 |
0.813 |
|
| 2022 |
Hossain S, Robbins N, Cowen LE. The GARP complex is required for filamentation in Candida albicans. Genetics. PMID 36226807 DOI: 10.1093/genetics/iyac152 |
0.669 |
|
| 2022 |
Case NT, Berman J, Blehert DS, Cramer RA, Cuomo C, Currie CR, Ene IV, Fisher MC, Fritz-Laylin LK, Gerstein AC, Glass NL, Gow NAR, Gurr SJ, Hittinger CT, Hohl TM, ... ... Cowen LE, et al. The future of fungi: threats and opportunities. G3 (Bethesda, Md.). PMID 36179219 DOI: 10.1093/g3journal/jkac224 |
0.784 |
|
| 2022 |
Robbins N, Cowen LE. Antifungal discovery. Current Opinion in Microbiology. 69: 102198. PMID 36037637 DOI: 10.1016/j.mib.2022.102198 |
0.664 |
|
| 2022 |
Revie NM, Iyer KR, Maxson ME, Zhang J, Yan S, Fernandes CM, Meyer KJ, Chen X, Skulska I, Fogal M, Sanchez H, Hossain S, Li S, Yashiroda Y, Hirano H, ... ... Cowen LE, et al. Targeting fungal membrane homeostasis with imidazopyrazoindoles impairs azole resistance and biofilm formation. Nature Communications. 13: 3634. PMID 35752611 DOI: 10.1038/s41467-022-31308-1 |
0.765 |
|
| 2022 |
Iyer KR, Kim SH, Robbins N, Cowen LE. Downregulation of Essential Genes in the Fungal Pathogen Candida auris. Methods in Molecular Biology (Clifton, N.J.). 2517: 111-126. PMID 35674949 DOI: 10.1007/978-1-0716-2417-3_9 |
0.702 |
|
| 2022 |
Lee Y, Liston SD, Lee D, Robbins N, Cowen LE. Functional analysis of the kinome reveals Hrr25 as a regulator of antifungal susceptibility. Iscience. 25: 104432. PMID 35663022 DOI: 10.1016/j.isci.2022.104432 |
0.83 |
|
| 2022 |
Robbins N, Cowen LE. Genomic Approaches to Antifungal Drug Target Identification and Validation. Annual Review of Microbiology. PMID 35650665 DOI: 10.1146/annurev-micro-041020-094524 |
0.687 |
|
| 2022 |
Kim SH, Steere L, Zhang YK, McGregor C, Hahne C, Zhou Y, Liu C, Cai Y, Zhou H, Chen X, Puumala E, Duncan D, Wright GD, Liu CT, Whitesell L, ... Cowen LE, et al. Inhibiting C-4 Methyl Sterol Oxidase with Novel Diazaborines to Target Fungal Plant Pathogens. Acs Chemical Biology. PMID 35584803 DOI: 10.1021/acschembio.2c00257 |
0.702 |
|
| 2022 |
Du Bois AC, Xue A, Pham C, Revie NM, Meyer KJ, Yashiroda Y, Boone C, Nodwell JR, Stogios P, Savchenko A, Robbins N, Iyer KR, Cowen LE. High-Throughput Chemical Screen Identifies a 2,5-Disubstituted Pyridine as an Inhibitor of Candida albicans Erg11. Msphere. e0007522. PMID 35531664 DOI: 10.1128/msphere.00075-22 |
0.694 |
|
| 2022 |
Stogios PJ, Liston SD, Semper C, Quade B, Michalska K, Evdokimova E, Ram S, Otwinowski Z, Borek D, Cowen LE, Savchenko A. Molecular analysis and essentiality of Aro1 shikimate biosynthesis multi-enzyme in . Life Science Alliance. 5. PMID 35512834 DOI: 10.26508/lsa.202101358 |
0.745 |
|
| 2022 |
Iyer KR, Robbins N, Cowen LE. The role of stress response pathways in antifungal tolerance and resistance. Iscience. 25: 103953. PMID 35281744 DOI: 10.1016/j.isci.2022.103953 |
0.705 |
|
| 2022 |
MacAlpine J, Robbins N, Cowen LE. Bacterial-Fungal Interactions and Their Impact on Microbial Pathogenesis. Molecular Ecology. PMID 35231147 DOI: 10.1111/mec.16411 |
0.806 |
|
| 2022 |
Case NT, Song M, Fulford AH, Graham HV, Orphan VJ, Stajich JE, Casadevall A, Mustard J, Heitman J, Lollar BS, Cowen LE. Exploring Space via Astromycology: A Report on the CIFAR Programs and Inaugural Joint Meeting. Astrobiology. PMID 35196462 DOI: 10.1089/ast.2021.0186 |
0.766 |
|
| 2022 |
Ottilie S, Luth MR, Hellemann E, Goldgof GM, Vigil E, Kumar P, Cheung AL, Song M, Godinez-Macias KP, Carolino K, Yang J, Lopez G, Abraham M, Tarsio M, LeBlanc E, ... ... Cowen LE, et al. Adaptive laboratory evolution in S. cerevisiae highlights role of transcription factors in fungal xenobiotic resistance. Communications Biology. 5: 128. PMID 35149760 DOI: 10.1038/s42003-022-03076-7 |
0.302 |
|
| 2021 |
Robbins N, Cowen LE. Antifungal drug resistance: Deciphering the mechanisms governing multidrug resistance in the fungal pathogen Candida glabrata. Current Biology : Cb. 31: R1520-R1523. PMID 34875240 DOI: 10.1016/j.cub.2021.09.071 |
0.673 |
|
| 2021 |
Fu C, Beattie SR, Jezewski AJ, Robbins N, Whitesell L, Krysan DJ, Cowen LE. Genetic analysis of Hsp90 function in Cryptococcus neoformans highlights key roles in stress tolerance and virulence. Genetics. PMID 34849848 DOI: 10.1093/genetics/iyab164 |
0.788 |
|
| 2021 |
Fu C, Zhang X, Veri AO, Iyer KR, Lash E, Xue A, Yan H, Revie NM, Wong C, Lin ZY, Polvi EJ, Liston SD, VanderSluis B, Hou J, Yashiroda Y, ... ... Cowen LE, et al. Leveraging machine learning essentiality predictions and chemogenomic interactions to identify antifungal targets. Nature Communications. 12: 6497. PMID 34764269 DOI: 10.1038/s41467-021-26850-3 |
0.784 |
|
| 2021 |
MacAlpine J, Daniel-Ivad M, Liu Z, Yano J, Revie NM, Todd RT, Stogios PJ, Sanchez H, O'Meara TR, Tompkins TA, Savchenko A, Selmecki A, Veri AO, Andes DR, Fidel PL, ... ... Cowen LE, et al. A small molecule produced by Lactobacillus species blocks Candida albicans filamentation by inhibiting a DYRK1-family kinase. Nature Communications. 12: 6151. PMID 34686660 DOI: 10.1038/s41467-021-26390-w |
0.806 |
|
| 2021 |
Hsu IS, Strome B, Lash E, Robbins N, Cowen LE, Moses AM. A functionally divergent intrinsically disordered region underlying the conservation of stochastic signaling. Plos Genetics. 17: e1009629. PMID 34506483 DOI: 10.1371/journal.pgen.1009629 |
0.603 |
|
| 2021 |
Case NT, Duah K, Larsen B, Wong CJ, Gingras AC, O'Meara TR, Robbins N, Veri AO, Whitesell L, Cowen LE. The macrophage-derived protein PTMA induces filamentation of the human fungal pathogen Candida albicans. Cell Reports. 36: 109584. PMID 34433036 DOI: 10.1016/j.celrep.2021.109584 |
0.797 |
|
| 2021 |
Hossain S, Veri AO, Liu Z, Iyer KR, O'Meara TR, Robbins N, Cowen LE. Mitochondrial perturbation reduces susceptibility to xenobiotics through altered efflux in Candida albicans. Genetics. PMID 34143207 DOI: 10.1093/genetics/iyab095 |
0.779 |
|
| 2021 |
Cowen LE, Heitman J. Showcasing Fungal Genetics & Genomics with the Genetics Society of America. Genetics. 217. PMID 33724422 DOI: 10.1093/genetics/iyaa034 |
0.364 |
|
| 2021 |
Hossain S, Lash E, Veri AO, Cowen LE. Functional connections between cell cycle and proteostasis in the regulation of Candida albicans morphogenesis. Cell Reports. 34: 108781. PMID 33626353 DOI: 10.1016/j.celrep.2021.108781 |
0.316 |
|
| 2021 |
Cowen LE, Heitman J. Showcasing Fungal Genetics & Genomics with the Genetics Society of America. G3 (Bethesda, Md.). 11. PMID 33585877 DOI: 10.1093/g3journal/jkaa041 |
0.364 |
|
| 2021 |
Iyer KR, Revie NM, Fu C, Robbins N, Cowen LE. Treatment strategies for cryptococcal infection: challenges, advances and future outlook. Nature Reviews. Microbiology. PMID 33558691 DOI: 10.1038/s41579-021-00511-0 |
0.781 |
|
| 2021 |
Marcyk PT, LeBlanc EV, Kuntz DA, Xue A, Ortiz F, Trilles R, Bengtson S, Kenney TMG, Huang DS, Robbins N, Williams NS, Krysan DJ, Privé GG, Whitesell L, Cowen LE, et al. Fungal-Selective Resorcylate Aminopyrazole Hsp90 Inhibitors: Optimization of Whole-Cell Anticryptococcal Activity and Insights into the Structural Origins of Cryptococcal Selectivity. Journal of Medicinal Chemistry. PMID 33444025 DOI: 10.1021/acs.jmedchem.0c01777 |
0.657 |
|
| 2020 |
Iyer KR, Camara K, Daniel-Ivad M, Trilles R, Pimentel-Elardo SM, Fossen JL, Marchillo K, Liu Z, Singh S, Muñoz JF, Kim SH, Porco JA, Cuomo CA, Williams NS, Ibrahim AS, ... ... Cowen LE, et al. An oxindole efflux inhibitor potentiates azoles and impairs virulence in the fungal pathogen Candida auris. Nature Communications. 11: 6429. PMID 33353950 DOI: 10.1038/s41467-020-20183-3 |
0.705 |
|
| 2020 |
Iyer KR, Robbins N, Cowen LE. Flow Cytometric Measurement of Efflux in Candida Species. Current Protocols in Microbiology. 59: e121. PMID 33047867 DOI: 10.1002/cpmc.121 |
0.606 |
|
| 2020 |
Xue A, Robbins N, Cowen LE. Advances in fungal chemical genomics for the discovery of new antifungal agents. Annals of the New York Academy of Sciences. PMID 32860238 DOI: 10.1111/Nyas.14484 |
0.713 |
|
| 2020 |
LeBlanc EV, Polvi EJ, Veri AO, Privé GG, Cowen LE. Structure-guided approaches to targeting stress responses in human fungal pathogens. The Journal of Biological Chemistry. PMID 32796038 DOI: 10.1074/Jbc.Rev120.013731 |
0.474 |
|
| 2020 |
Horianopoulos LC, Gluck-Thaler E, Benoit Gelber I, Cowen LE, Geddes-McAlister J, Landry CR, Schwartz IS, Scott JA, Sellam A, Sheppard DC, Spribille T, Subramaniam R, Walker AK, Harris SD, Shapiro RS, et al. The Canadian Fungal Research Network: current challenges and future opportunities. Canadian Journal of Microbiology. PMID 32717148 DOI: 10.1139/Cjm-2020-0263 |
0.552 |
|
| 2020 |
Liston SD, Whitesell L, McLellan CA, Mazitschek R, Petraitis V, Petraitiene R, Kavaliauskas P, Walsh TJ, Cowen LE. Antifungal activity of gepinacin-scaffold GPI anchor biosynthesis inhibitors with improved metabolic stability. Antimicrobial Agents and Chemotherapy. PMID 32661007 DOI: 10.1128/Aac.00899-20 |
0.76 |
|
| 2020 |
Kim SH, Liu C, Zhou Y, Zhang YK, McGregor C, Steere L, Frederick BH, Liu CT, Whitesell L, Cowen LE. Inhibiting Protein Prenylation with Benzoxaboroles to Target Fungal Plant Pathogens. Acs Chemical Biology. PMID 32573189 DOI: 10.1021/Acschembio.0C00290 |
0.456 |
|
| 2020 |
Case NT, Heitman J, Cowen LE. The Rise of Fungi: A Report on the CIFAR Program Inaugural Meeting. G3 (Bethesda, Md.). 10: 1837-1842. PMID 32482729 DOI: 10.1534/G3.120.401271 |
0.765 |
|
| 2020 |
Lee Y, Puumala E, Robbins N, Cowen LE. Antifungal Drug Resistance: Molecular Mechanisms in and Beyond. Chemical Reviews. PMID 32441527 DOI: 10.1021/Acs.Chemrev.0C00199 |
0.723 |
|
| 2020 |
Fisher MC, Gurr SJ, Cuomo CA, Blehert DS, Jin H, Stukenbrock EH, Stajich JE, Kahmann R, Boone C, Denning DW, Gow NAR, Klein BS, Kronstad JW, Sheppard DC, Taylor JW, ... ... Cowen LE, et al. Threats Posed by the Fungal Kingdom to Humans, Wildlife, and Agriculture. Mbio. 11. PMID 32371596 DOI: 10.1128/Mbio.00449-20 |
0.541 |
|
| 2020 |
Hossain S, Veri AO, Cowen LE. The Proteasome Governs Fungal Morphogenesis via Functional Connections with Hsp90 and cAMP-Protein Kinase A Signaling. Mbio. 11. PMID 32317319 DOI: 10.1128/Mbio.00290-20 |
0.453 |
|
| 2020 |
Revie NM, Robbins N, Whitesell L, Frost JR, Appavoo SD, Yudin AK, Cowen LE. Oxadiazole-Containing Macrocyclic Peptides Potentiate Azole Activity against Pathogenic Species. Msphere. 5. PMID 32269162 DOI: 10.1128/mSphere.00256-20 |
0.688 |
|
| 2020 |
Liston SD, Whitesell L, Kapoor M, Shaw KJ, Cowen LE. Enhanced efflux pump expression in mutants results in decreased manogepix susceptibility. Antimicrobial Agents and Chemotherapy. PMID 32179530 DOI: 10.1128/Aac.00261-20 |
0.781 |
|
| 2020 |
Iyer KR, Whitesell L, Porco JA, Henkel T, Brown LE, Robbins N, Cowen LE. Translation Inhibition by Rocaglates Activates a Species-Specific Cell Death Program in the Emerging Fungal Pathogen Candida auris. Mbio. 11. PMID 32156828 DOI: 10.1128/Mbio.03329-19 |
0.716 |
|
| 2020 |
Caplan T, Lorente-Macías Á, Stogios PJ, Evdokimova E, Hyde S, Wellington MA, Liston S, Iyer KR, Puumala E, Shekhar-Guturja T, Robbins N, Savchenko A, Krysan DJ, Whitesell L, Zuercher WJ, ... Cowen LE, et al. Overcoming Fungal Echinocandin Resistance through Inhibition of the Non-essential Stress Kinase Yck2. Cell Chemical Biology. PMID 31924499 DOI: 10.1016/J.Chembiol.2019.12.008 |
0.828 |
|
| 2019 |
Pourhaghighi R, O'Meara TR, Cowen LE, Emili A. Protein-Protein Interaction Profiling in Candida albicans Revealed by Biochemical Purification-Mass Spectrometry (BP/MS). Methods in Molecular Biology (Clifton, N.J.). 2049: 203-211. PMID 31602613 DOI: 10.1007/978-1-4939-9736-7_12 |
0.605 |
|
| 2019 |
Huang D, LeBlanc E, Shekhar-Guturja T, Robbins N, Krysan D, Pizarro JC, Whitesell L, Cowen L, Brown LE. Design and synthesis of fungal-selective resorcylate aminopyrazole Hsp90 inhibitors. Journal of Medicinal Chemistry. PMID 31513387 DOI: 10.1021/Acs.Jmedchem.9B00826 |
0.708 |
|
| 2019 |
O'Meara TR, O'Meara MJ, Polvi EJ, Pourhaghighi MR, Liston SD, Lin ZY, Veri AO, Emili A, Gingras AC, Cowen LE. Global proteomic analyses define an environmentally contingent Hsp90 interactome and reveal chaperone-dependent regulation of stress granule proteins and the R2TP complex in a fungal pathogen. Plos Biology. 17: e3000358. PMID 31283755 DOI: 10.1371/Journal.Pbio.3000358 |
0.807 |
|
| 2019 |
Kim SH, Iyer KR, Pardeshi L, Muñoz JF, Robbins N, Cuomo CA, Wong KH, Cowen LE. Erratum for Kim et al., "Genetic Analysis of Candida auris Implicates Hsp90 in Morphogenesis and Azole Tolerance and Cdr1 in Azole Resistance". Mbio. 10. PMID 30890611 DOI: 10.1128/Mbio.00346-19 |
0.647 |
|
| 2019 |
Guan G, Tao L, Yue H, Liang W, Gong J, Bing J, Zheng Q, Veri AO, Fan S, Robbins N, Cowen LE, Huang G. Environment-induced same-sex mating in the yeast Candida albicans through the Hsf1-Hsp90 pathway. Plos Biology. 17: e2006966. PMID 30865631 DOI: 10.1371/Journal.Pbio.2006966 |
0.659 |
|
| 2019 |
Kim SH, Iyer KR, Pardeshi L, Muñoz JF, Robbins N, Cuomo CA, Wong KH, Cowen LE. Genetic Analysis of Implicates Hsp90 in Morphogenesis and Azole Tolerance and Cdr1 in Azole Resistance. Mbio. 10. PMID 30696744 DOI: 10.1128/Mbio.02529-18 |
0.737 |
|
| 2019 |
Whitesell L, Robbins N, Huang DS, McLellan CA, Shekhar-Guturja T, LeBlanc EV, Nation CS, Hui R, Hutchinson A, Collins C, Chatterjee S, Trilles R, Xie JL, Krysan DJ, Lindquist S, ... ... Cowen LE, et al. Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus. Nature Communications. 10: 402. PMID 30679438 DOI: 10.1038/s41467-018-08248-w |
0.751 |
|
| 2019 |
Polvi EJ, Veri AO, Liu Z, Hossain S, Hyde S, Kim SH, Tebbji F, Sellam A, Todd RT, Xie JL, Lin ZY, Wong CJ, Shapiro RS, Whiteway M, Robbins N, ... ... Cowen LE, et al. Functional divergence of a global regulatory complex governing fungal filamentation. Plos Genetics. 15: e1007901. PMID 30615616 DOI: 10.1371/Journal.Pgen.1007901 |
0.761 |
|
| 2018 |
O'Meara TR, Cowen LE. Insights into the host-pathogen interaction: manipulation of macrophage pyroptosis. Microbial Cell (Graz, Austria). 5: 566-568. PMID 30533421 DOI: 10.15698/Mic2018.12.662 |
0.679 |
|
| 2018 |
O'Meara TR, Duah K, Guo CX, Maxson ME, Gaudet RG, Koselny K, Wellington M, Powers ME, MacAlpine J, O'Meara MJ, Veri AO, Grinstein S, Noble SM, Krysan D, Gray-Owen SD, ... Cowen LE, et al. High-Throughput Screening Identifies Genes Required for Induction of Macrophage Pyroptosis. Mbio. 9. PMID 30131363 DOI: 10.1128/Mbio.01581-18 |
0.796 |
|
| 2018 |
Dijck PV, Sjollema J, Cammue BP, Lagrou K, Berman J, d'Enfert C, Andes DR, Arendrup MC, Brakhage AA, Calderone R, Cantón E, Coenye T, Cos P, Cowen LE, Edgerton M, et al. Methodologies for and evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms. Microbial Cell (Graz, Austria). 5: 300-326. PMID 29992128 DOI: 10.15698/Mic2018.07.638 |
0.374 |
|
| 2018 |
Caplan T, Polvi EJ, Xie JL, Buckhalter S, Leach MD, Robbins N, Cowen LE. Functional Genomic Screening Reveals Core Modulators of Echinocandin Stress Responses in Candida albicans. Cell Reports. 23: 2292-2298. PMID 29791841 DOI: 10.1016/J.Celrep.2018.04.084 |
0.723 |
|
| 2018 |
Veri AO, Robbins N, Cowen LE. Regulation of the heat shock transcription factor Hsf1 in fungi: implications for temperature-dependent virulence traits. Fems Yeast Research. 18. PMID 29788061 DOI: 10.1093/Femsyr/Foy041 |
0.693 |
|
| 2018 |
Mount HO, Revie NM, Todd RT, Anstett K, Collins C, Costanzo M, Boone C, Robbins N, Selmecki A, Cowen LE. Global analysis of genetic circuitry and adaptive mechanisms enabling resistance to the azole antifungal drugs. Plos Genetics. 14: e1007319. PMID 29702647 DOI: 10.1371/Journal.Pgen.1007319 |
0.722 |
|
| 2018 |
Veri AO, Miao Z, Shapiro RS, Tebbji F, O'Meara TR, Kim SH, Colazo J, Tan K, Vyas VK, Whiteway M, Robbins N, Wong KH, Cowen LE. Tuning Hsf1 levels drives distinct fungal morphogenetic programs with depletion impairing Hsp90 function and overexpression expanding the target space. Plos Genetics. 14: e1007270. PMID 29590106 DOI: 10.1371/Journal.Pgen.1007270 |
0.814 |
|
| 2018 |
Maxson ME, Naj X, O'Meara TR, Plumb JD, Cowen LE, Grinstein S. Integrin-based diffusion barrier separates membrane domains enabling formation of microbiostatic frustrated phagosomes. Elife. 7. PMID 29553370 DOI: 10.7554/Elife.34798 |
0.605 |
|
| 2018 |
Revie NM, Iyer KR, Robbins N, Cowen LE. Antifungal drug resistance: evolution, mechanisms and impact. Current Opinion in Microbiology. 45: 70-76. PMID 29547801 DOI: 10.1016/J.Mib.2018.02.005 |
0.727 |
|
| 2018 |
Maxson ME, Naj X, O'Meara TR, Plumb JD, Cowen LE, Grinstein S. Author response: Integrin-based diffusion barrier separates membrane domains enabling the formation of microbiostatic frustrated phagosomes Elife. DOI: 10.7554/Elife.34798.042 |
0.581 |
|
| 2017 |
Xie JL, Bohovych I, Wong EOY, Lambert JP, Gingras AC, Khalimonchuk O, Cowen LE, Leach MD. Ydj1 governs fungal morphogenesis and stress response, and facilitates mitochondrial protein import via Mas1 and Mas2. Microbial Cell (Graz, Austria). 4: 342-361. PMID 29082232 DOI: 10.15698/Mic2017.10.594 |
0.334 |
|
| 2017 |
Xie JL, Qin L, Miao Z, Grys BT, Diaz JC, Ting K, Krieger JR, Tong J, Tan K, Leach MD, Ketela T, Moran MF, Krysan DJ, Boone C, Andrews BJ, ... ... Cowen LE, et al. The Candida albicans transcription factor Cas5 couples stress responses, drug resistance and cell cycle regulation. Nature Communications. 8: 499. PMID 28894103 DOI: 10.1038/S41467-017-00547-Y |
0.695 |
|
| 2017 |
Robbins N, Caplan T, Cowen LE. Molecular Evolution of Antifungal Drug Resistance. Annual Review of Microbiology. 71: 753-775. PMID 28886681 DOI: 10.1146/Annurev-Micro-030117-020345 |
0.71 |
|
| 2017 |
O'Meara TR, Robbins N, Cowen LE. The Hsp90 Chaperone Network Modulates Candida Virulence Traits. Trends in Microbiology. PMID 28549824 DOI: 10.1016/J.Tim.2017.05.003 |
0.796 |
|
| 2017 |
Xie JL, O'Meara TR, Polvi EJ, Robbins N, Cowen LE. Staurosporine Induces Filamentation in the Human Fungal Pathogen Candida albicans via Signaling through Cyr1 and Protein Kinase A. Msphere. 2. PMID 28261668 DOI: 10.1128/mSphere.00056-17 |
0.809 |
|
| 2016 |
Lee JA, Robbins N, Xie JL, Ketela T, Cowen LE. Functional Genomic Analysis of Candida albicans Adherence Reveals a Key Role for the Arp2/3 Complex in Cell Wall Remodelling and Biofilm Formation. Plos Genetics. 12: e1006452. PMID 27870871 DOI: 10.1371/Journal.Pgen.1006452 |
0.7 |
|
| 2016 |
Li X, Robbins N, O'Meara TR, Cowen LE. Extensive Functional Redundancy in the Regulation of Candida albicans Drug Resistance and Morphogenesis by Lysine Deacetylases Hos2, Hda1, Rpd3, and Rpd31. Molecular Microbiology. PMID 27868254 DOI: 10.1111/Mmi.13578 |
0.807 |
|
| 2016 |
Leach MD, Kim T, DiGregorio S, Collins C, Zhang Z, Duennwald ML, Cowen LE. Candida albicans Is Resistant to Polyglutamine Aggregation and Toxicity. G3 (Bethesda, Md.). PMID 27807047 DOI: 10.1534/G3.116.035675 |
0.703 |
|
| 2016 |
Xie JL, Grahl N, Sless T, Leach MD, Kim SH, Hogan DA, Robbins N, Cowen LE. Signaling through Lrg1, Rho1 and Pkc1 Governs Candida albicans Morphogenesis in Response to Diverse Cues. Plos Genetics. 12: e1006405. PMID 27788136 DOI: 10.1371/Journal.Pgen.1006405 |
0.701 |
|
| 2016 |
Robbins N, Wright GD, Cowen LE. Antifungal Drugs: The Current Armamentarium and Development of New Agents. Microbiology Spectrum. 4. PMID 27763259 DOI: 10.1128/Microbiolspec.Funk-0002-2016 |
0.699 |
|
| 2016 |
Shekhar-Guturja T, Tebung WA, Mount H, Liu N, Köhler JR, Whiteway M, Cowen LE. Beauvericin Potentiates Azole Activity via Inhibition of Multidrug Efflux, Blocks C. albicans Morphogenesis, and is Effluxed via Yor1 and Circuitry Controlled by Zcf29. Antimicrobial Agents and Chemotherapy. PMID 27736764 DOI: 10.1128/Aac.01959-16 |
0.512 |
|
| 2016 |
Polvi EJ, Averette AF, Lee SC, Kim T, Bahn YS, Veri AO, Robbins N, Heitman J, Cowen LE. Metal Chelation as a Powerful Strategy to Probe Cellular Circuitry Governing Fungal Drug Resistance and Morphogenesis. Plos Genetics. 12: e1006350. PMID 27695031 DOI: 10.1371/Journal.Pgen.1006350 |
0.778 |
|
| 2016 |
Shekhar-Guturja T, Gunaherath GM, Wijeratne EM, Lambert JP, Averette AF, Lee SC, Kim T, Bahn YS, Tripodi F, Ammar R, Döhl K, Niewola-Staszkowska K, Schmitt L, Loewith RJ, Roth FP, ... ... Cowen LE, et al. Dual action antifungal small molecule modulates multidrug efflux and TOR signaling. Nature Chemical Biology. PMID 27571477 DOI: 10.1038/Nchembio.2165 |
0.628 |
|
| 2016 |
O'Meara TR, Veri AO, Polvi EJ, Li X, Valaei SF, Diezmann S, Cowen LE. Mapping the Hsp90 Genetic Network Reveals Ergosterol Biosynthesis and Phosphatidylinositol-4-Kinase Signaling as Core Circuitry Governing Cellular Stress. Plos Genetics. 12: e1006142. PMID 27341673 DOI: 10.1371/Journal.Pgen.1006142 |
0.728 |
|
| 2016 |
Leach MD, Farrer RA, Tan K, Miao Z, Walker LA, Cuomo CA, Wheeler RT, Brown AJ, Wong KH, Cowen LE. Hsf1 and Hsp90 orchestrate temperature-dependent global transcriptional remodelling and chromatin architecture in Candida albicans. Nature Communications. 7: 11704. PMID 27226156 DOI: 10.1038/Ncomms11704 |
0.368 |
|
| 2015 |
Hill JA, Cowen LE. Using combination therapy to thwart drug resistance. Future Microbiology. 10: 1719-26. PMID 26597425 DOI: 10.2217/Fmb.15.68 |
0.579 |
|
| 2015 |
Kim SH, Clark ST, Surendra A, Copeland JK, Wang PW, Ammar R, Collins C, Tullis DE, Nislow C, Hwang DM, Guttman DS, Cowen LE. Global Analysis of the Fungal Microbiome in Cystic Fibrosis Patients Reveals Loss of Function of the Transcriptional Repressor Nrg1 as a Mechanism of Pathogen Adaptation. Plos Pathogens. 11: e1005308. PMID 26588216 DOI: 10.1371/Journal.Ppat.1005308 |
0.412 |
|
| 2015 |
Diezmann S, Leach MD, Cowen LE. Functional Divergence of Hsp90 Genetic Interactions in Biofilm and Planktonic Cellular States. Plos One. 10: e0137947. PMID 26367740 DOI: 10.1371/Journal.Pone.0137947 |
0.421 |
|
| 2015 |
O'Meara TR, Veri AO, Ketela T, Jiang B, Roemer T, Cowen LE. Global analysis of fungal morphology exposes mechanisms of host cell escape. Nature Communications. 6: 6741. PMID 25824284 DOI: 10.1038/Ncomms7741 |
0.69 |
|
| 2015 |
Polvi EJ, Li X, O'Meara TR, Leach MD, Cowen LE. Opportunistic yeast pathogens: reservoirs, virulence mechanisms, and therapeutic strategies. Cellular and Molecular Life Sciences : Cmls. 72: 2261-87. PMID 25700837 DOI: 10.1007/S00018-015-1860-Z |
0.717 |
|
| 2015 |
Hill JA, O'Meara TR, Cowen LE. Fitness Trade-Offs Associated with the Evolution of Resistance to Antifungal Drug Combinations. Cell Reports. PMID 25660029 DOI: 10.1016/J.Celrep.2015.01.009 |
0.766 |
|
| 2015 |
Cowen LE, Sanglard D, Howard SJ, Rogers PD, Perlin DS. Mechanisms of Antifungal Drug Resistance. Cold Spring Harbor Perspectives in Medicine. 5: a019752. PMID 25384768 DOI: 10.1101/Cshperspect.A019752 |
0.423 |
|
| 2014 |
Leach MD, Cowen LE. Membrane fluidity and temperature sensing are coupled via circuitry comprised of Ole1, Rsp5, and Hsf1 in Candida albicans. Eukaryotic Cell. 13: 1077-84. PMID 24951438 DOI: 10.1128/Ec.00138-14 |
0.344 |
|
| 2014 |
Xie JL, Polvi EJ, Shekhar-Guturja T, Cowen LE. Elucidating drug resistance in human fungal pathogens. Future Microbiology. 9: 523-42. PMID 24810351 DOI: 10.2217/Fmb.14.18 |
0.485 |
|
| 2014 |
Veri A, Cowen LE. Progress and prospects for targeting Hsp90 to treat fungal infections. Parasitology. 141: 1127-37. PMID 24560124 DOI: 10.1017/S0031182013002072 |
0.453 |
|
| 2014 |
O'Meara TR, Cowen LE. Hsp90-dependent regulatory circuitry controlling temperature-dependent fungal development and virulence. Cellular Microbiology. 16: 473-81. PMID 24438186 DOI: 10.1111/Cmi.12266 |
0.703 |
|
| 2014 |
Leach MD, Cowen LE. To sense or die: Mechanisms of temperature sensing in fungal pathogens Current Fungal Infection Reports. 8: 185-191. DOI: 10.1007/S12281-014-0182-1 |
0.34 |
|
| 2013 |
Hill JA, Ammar R, Torti D, Nislow C, Cowen LE. Genetic and genomic architecture of the evolution of resistance to antifungal drug combinations. Plos Genetics. 9: e1003390. PMID 23593013 DOI: 10.1371/Journal.Pgen.1003390 |
0.637 |
|
| 2013 |
Cowen LE. The fungal Achilles' heel: targeting Hsp90 to cripple fungal pathogens. Current Opinion in Microbiology. 16: 377-84. PMID 23588026 DOI: 10.1016/J.Mib.2013.03.005 |
0.475 |
|
| 2013 |
Leach MD, Cowen LE. Surviving the heat of the moment: a fungal pathogens perspective. Plos Pathogens. 9: e1003163. PMID 23505364 DOI: 10.1371/Journal.Ppat.1003163 |
0.343 |
|
| 2012 |
Leach MD, Budge S, Walker L, Munro C, Cowen LE, Brown AJ. Hsp90 orchestrates transcriptional regulation by Hsf1 and cell wall remodelling by MAPK signalling during thermal adaptation in a pathogenic yeast. Plos Pathogens. 8: e1003069. PMID 23300438 DOI: 10.1371/Journal.Ppat.1003069 |
0.372 |
|
| 2012 |
Shapiro RS, Ryan O, Boone C, Cowen LE. Regulatory circuitry governing morphogenesis in Saccharomyces cerevisiae and Candida albicans. Cell Cycle (Georgetown, Tex.). 11: 4294-5. PMID 23095675 DOI: 10.4161/Cc.22608 |
0.631 |
|
| 2012 |
Robbins N, Leach MD, Cowen LE. Lysine deacetylases Hda1 and Rpd3 regulate Hsp90 function thereby governing fungal drug resistance. Cell Reports. 2: 878-88. PMID 23041319 DOI: 10.1016/J.Celrep.2012.08.035 |
0.711 |
|
| 2012 |
Shapiro RS, Cowen LE. Thermal control of microbial development and virulence: molecular mechanisms of microbial temperature sensing. Mbio. 3. PMID 23033469 DOI: 10.1128/Mbio.00238-12 |
0.574 |
|
| 2012 |
Ryan O, Shapiro RS, Kurat CF, Mayhew D, Baryshnikova A, Chin B, Lin ZY, Cox MJ, Vizeacoumar F, Cheung D, Bahr S, Tsui K, Tebbji F, Sellam A, Istel F, ... ... Cowen LE, et al. Global gene deletion analysis exploring yeast filamentous growth. Science (New York, N.Y.). 337: 1353-6. PMID 22984072 DOI: 10.1126/Science.1224339 |
0.595 |
|
| 2012 |
Leach MD, Klipp E, Cowen LE, Brown AJ. Fungal Hsp90: a biological transistor that tunes cellular outputs to thermal inputs. Nature Reviews. Microbiology. 10: 693-704. PMID 22976491 DOI: 10.1038/Nrmicro2875 |
0.349 |
|
| 2012 |
Shapiro RS, Zaas AK, Betancourt-Quiroz M, Perfect JR, Cowen LE. The Hsp90 co-chaperone Sgt1 governs Candida albicans morphogenesis and drug resistance. Plos One. 7: e44734. PMID 22970302 DOI: 10.1371/Journal.Pone.0044734 |
0.666 |
|
| 2012 |
Singh-Babak SD, Shekhar T, Smith AM, Giaever G, Nislow C, Cowen LE. A novel calcineurin-independent activity of cyclosporin A in Saccharomyces cerevisiae. Molecular Biosystems. 8: 2575-84. PMID 22751784 DOI: 10.1039/C2Mb25107H |
0.821 |
|
| 2012 |
Shapiro RS, Cowen LE. Uncovering cellular circuitry controlling temperature-dependent fungal morphogenesis. Virulence. 3: 400-4. PMID 22722238 DOI: 10.4161/Viru.20979 |
0.592 |
|
| 2012 |
Singh-Babak SD, Babak T, Diezmann S, Hill JA, Xie JL, Chen YL, Poutanen SM, Rennie RP, Heitman J, Cowen LE. Global analysis of the evolution and mechanism of echinocandin resistance in Candida glabrata. Plos Pathogens. 8: e1002718. PMID 22615574 DOI: 10.1371/Journal.Ppat.1002718 |
0.814 |
|
| 2012 |
Diezmann S, Michaut M, Shapiro RS, Bader GD, Cowen LE. Mapping the Hsp90 genetic interaction network in Candida albicans reveals environmental contingency and rewired circuitry. Plos Genetics. 8: e1002562. PMID 22438817 DOI: 10.1371/Journal.Pgen.1002562 |
0.609 |
|
| 2012 |
Shapiro RS, Sellam A, Tebbji F, Whiteway M, Nantel A, Cowen LE. Pho85, Pcl1, and Hms1 signaling governs Candida albicans morphogenesis induced by high temperature or Hsp90 compromise. Current Biology : Cb. 22: 461-70. PMID 22365851 DOI: 10.1016/J.Cub.2012.01.062 |
0.615 |
|
| 2012 |
Senn H, Shapiro RS, Cowen LE. Cdc28 provides a molecular link between Hsp90, morphogenesis, and cell cycle progression in Candida albicans. Molecular Biology of the Cell. 23: 268-83. PMID 22090345 DOI: 10.1091/Mbc.E11-08-0729 |
0.613 |
|
| 2012 |
Xie J, Singh-Babak S, Cowen L. Minimum Inhibitory Concentration (MIC) Assay for Antifungal Drugs Bio-Protocol. 2. DOI: 10.21769/bioprotoc.252 |
0.778 |
|
| 2011 |
Lissina E, Young B, Urbanus ML, Guan XL, Lowenson J, Hoon S, Baryshnikova A, Riezman I, Michaut M, Riezman H, Cowen LE, Wenk MR, Clarke SG, Giaever G, Nislow C. A systems biology approach reveals the role of a novel methyltransferase in response to chemical stress and lipid homeostasis. Plos Genetics. 7: e1002332. PMID 22028670 DOI: 10.1371/Journal.Pgen.1002332 |
0.415 |
|
| 2011 |
Robbins N, Uppuluri P, Nett J, Rajendran R, Ramage G, Lopez-Ribot JL, Andes D, Cowen LE. Hsp90 governs dispersion and drug resistance of fungal biofilms. Plos Pathogens. 7: e1002257. PMID 21931556 DOI: 10.1371/Journal.Ppat.1002257 |
0.725 |
|
| 2011 |
Shapiro RS, Robbins N, Cowen LE. Regulatory circuitry governing fungal development, drug resistance, and disease. Microbiology and Molecular Biology Reviews : Mmbr. 75: 213-67. PMID 21646428 DOI: 10.1128/Mmbr.00045-10 |
0.796 |
|
| 2011 |
Leach MD, Tyc K, Shapiro R, Cowen L, Klipp E, Brown AJ. Modelling the regulation of thermal adaptation by Hsf1 and Hsp90 in Candida albicans F1000research. 2. DOI: 10.7490/F1000Research.1452.1 |
0.541 |
|
| 2010 |
Shapiro RS, Cowen L. Coupling temperature sensing and development: Hsp90 regulates morphogenetic signalling in Candida albicans. Virulence. 1: 45-8. PMID 21178413 DOI: 10.4161/Viru.1.1.10320 |
0.605 |
|
| 2010 |
LaFayette SL, Collins C, Zaas AK, Schell WA, Betancourt-Quiroz M, Gunatilaka AA, Perfect JR, Cowen LE. PKC signaling regulates drug resistance of the fungal pathogen Candida albicans via circuitry comprised of Mkc1, calcineurin, and Hsp90. Plos Pathogens. 6: e1001069. PMID 20865172 DOI: 10.1371/Journal.Ppat.1001069 |
0.52 |
|
| 2010 |
Robbins N, Collins C, Morhayim J, Cowen LE. Metabolic control of antifungal drug resistance. Fungal Genetics and Biology : Fg & B. 47: 81-93. PMID 19595784 DOI: 10.1016/J.Fgb.2009.07.004 |
0.712 |
|
| 2009 |
Selmecki AM, Dulmage K, Cowen LE, Anderson JB, Berman J. Acquisition of aneuploidy provides increased fitness during the evolution of antifungal drug resistance. Plos Genetics. 5: e1000705. PMID 19876375 DOI: 10.1371/Journal.Pgen.1000705 |
0.551 |
|
| 2009 |
Cowen LE. Hsp90 orchestrates stress response signaling governing fungal drug resistance. Plos Pathogens. 5: e1000471. PMID 19714223 DOI: 10.1371/Journal.Ppat.1000471 |
0.445 |
|
| 2009 |
Singh SD, Robbins N, Zaas AK, Schell WA, Perfect JR, Cowen LE. Hsp90 governs echinocandin resistance in the pathogenic yeast Candida albicans via calcineurin. Plos Pathogens. 5: e1000532. PMID 19649312 DOI: 10.1371/Journal.Ppat.1000532 |
0.78 |
|
| 2009 |
Shapiro RS, Uppuluri P, Zaas AK, Collins C, Senn H, Perfect JR, Heitman J, Cowen LE. Hsp90 orchestrates temperature-dependent Candida albicans morphogenesis via Ras1-PKA signaling. Current Biology : Cb. 19: 621-9. PMID 19327993 DOI: 10.1016/J.Cub.2009.03.017 |
0.697 |
|
| 2009 |
Cowen LE, Singh SD, Köhler JR, Collins C, Zaas AK, Schell WA, Aziz H, Mylonakis E, Perfect JR, Whitesell L, Lindquist S. Harnessing Hsp90 function as a powerful, broadly effective therapeutic strategy for fungal infectious disease Proceedings of the National Academy of Sciences of the United States of America. 106: 2818-2823. PMID 19196973 DOI: 10.1073/Pnas.0813394106 |
0.729 |
|
| 2008 |
Shen J, Cowen LE, Griffin AM, Chan L, Köhler JR. The Candida albicans pescadillo homolog is required for normal hypha-to-yeast morphogenesis and yeast proliferation. Proceedings of the National Academy of Sciences of the United States of America. 105: 20918-23. PMID 19075239 DOI: 10.1073/Pnas.0809147105 |
0.426 |
|
| 2008 |
Cowen LE, Steinbach WJ. Stress, drugs, and evolution: the role of cellular signaling in fungal drug resistance. Eukaryotic Cell. 7: 747-64. PMID 18375617 DOI: 10.1128/Ec.00041-08 |
0.373 |
|
| 2008 |
Cowen LE. The evolution of fungal drug resistance: modulating the trajectory from genotype to phenotype. Nature Reviews. Microbiology. 6: 187-98. PMID 18246082 DOI: 10.1038/Nrmicro1835 |
0.448 |
|
| 2006 |
Cowen LE, Carpenter AE, Matangkasombut O, Fink GR, Lindquist S. Genetic architecture of Hsp90-dependent drug resistance. Eukaryotic Cell. 5: 2184-8. PMID 17056742 DOI: 10.1128/Ec.00274-06 |
0.604 |
|
| 2005 |
Cowen LE, Lindquist S. Hsp90 potentiates the rapid evolution of new traits: drug resistance in diverse fungi. Science (New York, N.Y.). 309: 2185-9. PMID 16195452 DOI: 10.1126/Science.1118370 |
0.603 |
|
| 2003 |
Anderson JB, Sirjusingh C, Parsons AB, Boone C, Wickens C, Cowen LE, Kohn LM. Mode of selection and experimental evolution of antifungal drug resistance in Saccharomyces cerevisiae. Genetics. 163: 1287-98. PMID 12702675 |
0.653 |
|
| 2002 |
Cowen LE, Anderson JB, Kohn LM. Evolution of drug resistance in Candida albicans. Annual Review of Microbiology. 56: 139-65. PMID 12142485 DOI: 10.1146/Annurev.Micro.56.012302.160907 |
0.723 |
|
| 2002 |
Cowen LE, Nantel A, Whiteway MS, Thomas DY, Tessier DC, Kohn LM, Anderson JB. Population genomics of drug resistance in Candida albicans. Proceedings of the National Academy of Sciences of the United States of America. 99: 9284-9. PMID 12089321 DOI: 10.1073/Pnas.102291099 |
0.688 |
|
| 2001 |
Cowen LE. Predicting the emergence of resistance to antifungal drugs Fems Microbiology Letters. 204: 1-7. PMID 11682169 DOI: 10.1111/J.1574-6968.2001.Tb10853.X |
0.395 |
|
| 2001 |
Cowen LE, Kohn LM, Anderson JB. Divergence in fitness and evolution of drug resistance in experimental populations of Candida albicans. Journal of Bacteriology. 183: 2971-8. PMID 11325923 DOI: 10.1128/Jb.183.10.2971-2978.2001 |
0.695 |
|
| 2001 |
Luu LN, Cowen LE, Sirjusingh C, Kohn LM, Anderson JB. Multilocus genotyping indicates that the ability to invade the bloodstream is widespread among Candida albicans isolates. Journal of Clinical Microbiology. 39: 1657-60. PMID 11283111 DOI: 10.1128/Jcm.39.4.1657-1660.2001 |
0.625 |
|
| 2001 |
Anderson JB, Wickens C, Khan M, Cowen LE, Federspiel N, Jones T, Kohn LM. Infrequent genetic exchange and recombination in the mitochondrial genome of Candida albicans. Journal of Bacteriology. 183: 865-72. PMID 11208783 DOI: 10.1128/Jb.183.3.865-872.2001 |
0.643 |
|
| 2000 |
Cowen LE, Sanglard D, Calabrese D, Sirjusingh C, Anderson JB, Kohn LM. Evolution of drug resistance in experimental populations of Candida albicans. Journal of Bacteriology. 182: 1515-22. PMID 10692355 DOI: 10.1128/Jb.182.6.1515-1522.2000 |
0.692 |
|
| 1999 |
Cowen LE, Sirjusingh C, Summerbell RC, Walmsley S, Richardson S, Kohn LM, Anderson JB. Multilocus genotypes and DNA fingerprints Do not predict variation in azole resistance among clinical isolates of Candida albicans. Antimicrobial Agents and Chemotherapy. 43: 2930-8. PMID 10582885 DOI: 10.1128/Aac.43.12.2930 |
0.667 |
|
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