☰

Sathish Srinivasan, Ph.D. - Publications

Affiliations: 
2009 University of Miami, Coral Gables, FL 
Area:
Molecular Biology, Pharmacology, Endocrinology Biology
Tree Info Grants Similar researchers PubMed Report error

25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Min J, Nwachukwu JC, Min CK, Njeri JW, Srinivasan S, Rangarajan ES, Nettles CC, Sanabria Guillen V, Ziegler Y, Yan S, Carlson KE, Hou Y, Kim SH, Novick S, Pascal BD, et al. Dual-mechanism estrogen receptor inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34452998 DOI: 10.1073/pnas.2101657118  0.3
2020 Katzenellenbogen JA, Min J, Srinivasan S, Rangarajan ES, Nwachukwu JC, Guillen VS, Ziegler Y, Yan S, Carlson KE, Hou Y, Kim SH, Izard T, Houtman R, Nettles KW, Katzenellenbogen BS. Abstract P6-04-10: Combining direct and indirect modes of antiestrogen ligand antagonism of estrogen receptor activity in breast cancer Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-P6-04-10  0.379
2017 Min J, Guillen VS, Sharma A, Zhao Y, Ziegler Y, Gong P, Mayne CG, Srinivasan S, Kim SH, Carlson KE, Nettles KW, Katzenellenbogen BS, Katzenellenbogen JA. Adamantyl Antiestrogens with Novel Side Chains Reveal a Spectrum of Activities in Suppressing Estrogen Receptor (ER)-Mediated Activities in Breast Cancer Cells. Journal of Medicinal Chemistry. PMID 28657320 DOI: 10.1021/Acs.Jmedchem.7B00585  0.383
2017 Stender JD, Nwachukwu JC, Kastrati I, Kim Y, Strid T, Yakir M, Srinivasan S, Nowak J, Izard T, Rangarajan ES, Carlson KE, Katzenellenbogen JA, Yao XQ, Grant BJ, Leong HS, et al. Structural and Molecular Mechanisms of Cytokine-Mediated Endocrine Resistance in Human Breast Cancer Cells. Molecular Cell. 65: 1122-1135.e5. PMID 28306507 DOI: 10.1016/J.Molcel.2017.02.008  0.344
2017 Josan J, Pokludova K, Devi S, Srinivasan S, Katzenellenbogen J, Nettles K. Abstract P2-08-07: Anti-proliferative and anti-inflammatory estrogen receptor agents for treatment of endocrine-resistant breast cancer Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-P2-08-07  0.301
2016 Nwachukwu JC, Srinivasan S, Bruno NE, Nowak J, Wright NJ, Minutolo F, Rangarajan ES, Izard T, Yao XQ, Grant BJ, Kojetin DJ, Elemento O, Katzenellenbogen JA, Nettles KW. Systems Structural Biology Analysis of Ligand Effects on ERα Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies. Cell Chemical Biology. PMID 28042045 DOI: 10.1016/J.Chembiol.2016.11.014  0.372
2016 Sharma N, Carlson KE, Nwachukwu JC, Srinivasan S, Sharma A, Nettles KW, Katzenellenbogen JA. Exploring the Structural Compliancy versus Specificity of the Estrogen Receptor Using Isomeric Three-Dimensional Ligands. Acs Chemical Biology. PMID 28032978 DOI: 10.1021/Acschembio.6B00918  0.391
2016 Jin Z, Lin H, Srinivasan S, Nwachukwu JC, Bruno N, Griffin PR, Nettles KW, Kamenecka TM. Synthesis of novel steroidal agonists, partial agonists, and antagonists for the glucocorticoid receptor. Bioorganic & Medicinal Chemistry Letters. PMID 27919657 DOI: 10.1016/J.Bmcl.2016.11.007  0.348
2016 Srinivasan S, Nwachukwu JC, Bruno NE, Dharmarajan V, Goswami D, Kastrati I, Novick S, Nowak J, Cavett V, Zhou HB, Boonmuen N, Zhao Y, Min J, Frasor J, Katzenellenbogen BS, et al. Full antagonism of the estrogen receptor without a prototypical ligand side chain. Nature Chemical Biology. PMID 27870835 DOI: 10.1038/Nchembio.2236  0.368
2016 Nwachukwu JC, Srinivasan S, Zheng Y, Wang S, Min J, Dong C, Liao Z, Nowak J, Wright NJ, Houtman R, Carlson KE, Josan JS, Elemento O, Katzenellenbogen JA, Zhou HB, et al. Predictive features of ligand-specific signaling through the estrogen receptor. Molecular Systems Biology. 12: 864. PMID 27107013 DOI: 10.15252/Msb.20156701  0.386
2015 Kojetin DJ, Matta-Camacho E, Hughes TS, Srinivasan S, Nwachukwu JC, Cavett V, Nowak J, Chalmers MJ, Marciano DP, Kamenecka TM, Shulman AI, Rance M, Griffin PR, Bruning JB, Nettles KW. Structural mechanism for signal transduction in RXR nuclear receptor heterodimers. Nature Communications. 6: 8013. PMID 26289479 DOI: 10.1038/Ncomms9013  0.358
2015 Zhao Y, Gong P, Chen Y, Nwachukwu JC, Srinivasan S, Ko C, Bagchi MK, Taylor RN, Korach KS, Nettles KW, Katzenellenbogen JA, Katzenellenbogen BS. Dual suppression of estrogenic and inflammatory activities for targeting of endometriosis. Science Translational Medicine. 7: 271ra9. PMID 25609169 DOI: 10.1126/Scitranslmed.3010626  0.336
2014 Nwachukwu JC, Srinivasan S, Bruno NE, Parent AA, Hughes TS, Pollock JA, Gjyshi O, Cavett V, Nowak J, Garcia-Ordonez RD, Houtman R, Griffin PR, Kojetin DJ, Katzenellenbogen JA, Conkright MD, et al. Resveratrol modulates the inflammatory response via an estrogen receptor-signal integration network. Elife. 3: e02057. PMID 24771768 DOI: 10.7554/Elife.02057  0.318
2014 Liao ZQ, Dong C, Carlson KE, Srinivasan S, Nwachukwu JC, Chesnut RW, Sharma A, Nettles KW, Katzenellenbogen JA, Zhou HB. Triaryl-substituted Schiff bases are high-affinity subtype-selective ligands for the estrogen receptor. Journal of Medicinal Chemistry. 57: 3532-45. PMID 24708493 DOI: 10.1021/Jm500268J  0.337
2014 Zhou W, Srinivasan S, Nawaz Z, Slingerland JM. ERα, SKP2 and E2F-1 form a feed forward loop driving late ERα targets and G1 cell cycle progression. Oncogene. 33: 2341-53. PMID 23770852 DOI: 10.1038/Onc.2013.197  0.565
2014 Nwachukwu JC, Srinivasan S, Bruno NE, Parent AA, Hughes TS, Pollock JA, Gjyshi O, Cavett V, Nowak J, Garcia-Ordonez RD, Houtman R, Griffin PR, Kojetin DJ, Katzenellenbogen JA, Conkright MD, et al. Author response: Resveratrol modulates the inflammatory response via an estrogen receptor-signal integration network Elife. DOI: 10.7554/Elife.02057.040  0.305
2013 Min J, Wang P, Srinivasan S, Nwachukwu JC, Guo P, Huang M, Carlson KE, Katzenellenbogen JA, Nettles KW, Zhou HB. Thiophene-core estrogen receptor ligands having superagonist activity. Journal of Medicinal Chemistry. 56: 3346-66. PMID 23586645 DOI: 10.1021/Jm400157E  0.374
2013 Srinivasan S, Nwachukwu JC, Parent AA, Cavett V, Nowak J, Hughes TS, Kojetin DJ, Katzenellenbogen JA, Nettles KW. Ligand-binding dynamics rewire cellular signaling via estrogen receptor-α. Nature Chemical Biology. 9: 326-32. PMID 23524984 DOI: 10.1038/Nchembio.1214  0.364
2012 Zhu M, Zhang C, Nwachukwu JC, Srinivasan S, Cavett V, Zheng Y, Carlson KE, Dong C, Katzenellenbogen JA, Nettles KW, Zhou HB. Bicyclic core estrogens as full antagonists: synthesis, biological evaluation and structure-activity relationships of estrogen receptor ligands based on bridged oxabicyclic core arylsulfonamides. Organic & Biomolecular Chemistry. 10: 8692-700. PMID 23033157 DOI: 10.1039/C2Ob26531A  0.415
2012 Zheng Y, Zhu M, Srinivasan S, Nwachukwu JC, Cavett V, Min J, Carlson KE, Wang P, Dong C, Katzenellenbogen JA, Nettles KW, Zhou HB. Development of selective estrogen receptor modulator (SERM)-like activity through an indirect mechanism of estrogen receptor antagonism: defining the binding mode of 7-oxabicyclo[2.2.1]hept-5-ene scaffold core ligands. Chemmedchem. 7: 1094-100. PMID 22517684 DOI: 10.1002/Cmdc.201200048  0.388
2011 Srinivasan S, Nawaz Z. E3 ubiquitin protein ligase, E6-associated protein (E6-AP) regulates PI3K-Akt signaling and prostate cell growth. Biochimica Et Biophysica Acta. 1809: 119-27. PMID 20826237 DOI: 10.1016/J.Bbagrm.2010.08.011  0.547
2010 Matthews JM, Natkunam Y, Srinivasan S, Patricelli M, Nomanbhoy T, Cerchietti L, Melnick AM, Lossos IS. STAT3, Constitutively Activated In ABC-Like DLBCL, Regulates Expression of the Prognostic Factor Cyclin D2 Blood. 116: 705-705. DOI: 10.1182/Blood.V116.21.705.705  0.323
2010 Srinivasan S, Nawaz Z. Molecular biology of estrogen receptor action Hormones, Brain and Behavior Online. 1187-1220. DOI: 10.1016/B978-008088783-8.00035-8  0.583
2006 Khan OY, Fu G, Ismail A, Srinivasan S, Cao X, Tu Y, Lu S, Nawaz Z. Multifunction steroid receptor coactivator, E6-associated protein, is involved in development of the prostate gland. Molecular Endocrinology (Baltimore, Md.). 20: 544-59. PMID 16254014 DOI: 10.1210/Me.2005-0110  0.543
2006 Zafar S, Srinivasan S, Nawaz Z. E6-Associated Protein (E6-AP): A Potential Tumor Suppressor Protein for Non-Hodgkin Lymphoma. Blood. 108: 4336-4336. DOI: 10.1182/Blood.V108.11.4336.4336  0.529
Show low-probability matches.