J. Christopher Gant - Publications

Affiliations: 
Pharmacology University of Kentucky, Lexington, KY 
Area:
neuroscience, learning & memory, AHPs, intracellular calcium

18 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Sompol P, Gollihue JL, Weiss BE, Lin RL, Case SL, Kraner SD, Weekman EM, Gant JC, Rogers CB, Niedowicz DM, Sudduth TL, Powell DK, Lin AL, Nelson PT, Thibault O, et al. Targeting astrocyte signaling alleviates cerebrovascular and synaptic function deficits in a diet-based mouse model of small cerebral vessel disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 36746627 DOI: 10.1523/JNEUROSCI.1333-22.2023  0.675
2020 Ghoweri AO, Ouillette L, Frazier HN, Anderson KL, Lin RL, Gant JC, Parent R, Moore S, Murphy GG, Thibault O. Electrophysiological and Imaging Calcium Biomarkers of Aging in Male and Female 5×FAD Mice. Journal of Alzheimer's Disease : Jad. PMID 33164928 DOI: 10.3233/JAD-200109  0.64
2020 Ghoweri AO, Gagolewicz P, Frazier HN, Gant JC, Andrew RD, Bennett BM, Thibault O. Neuronal Calcium Imaging, Excitability, and Plasticity Changes in the Aldh2-/- Mouse Model of Sporadic Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 32925058 DOI: 10.3233/Jad-200617  0.648
2019 Porter N, Brewer L, Anderson K, Hoffman J, Thibault J, Gant J, Frazier H, Ghower A, Kraner S, Landfield P, Blalock E, Thibault O. Sexually Dimorphic Effects of Dietary Vitamin D3 Supplementation on Cognition and the Gut Microbiome in Aging Rats (P14-006-19). Current Developments in Nutrition. 3. PMID 31223956 DOI: 10.1093/cdn/nzz052.P14-006-19  0.742
2018 Gant JC, Kadish I, Chen KC, Thibault O, Blalock EM, Porter NM, Landfield PW. Aging-Related Calcium Dysregulation in Rat Entorhinal Neurons Homologous with the Human Entorhinal Neurons in which Alzheimer's Disease Neurofibrillary Tangles First Appear. Journal of Alzheimer's Disease : Jad. PMID 30412490 DOI: 10.3233/Jad-180618  0.787
2017 Gant JC, Blalock EM, Chen KC, Kadish I, Thibault O, Porter NM, Landfield PW. FK506-Binding Protein 12.6/1b, a negative regulator of [Ca2+], rescues memory and restores genomic regulation in the hippocampus of aging rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29255009 DOI: 10.1523/Jneurosci.2234-17.2017  0.802
2017 Berkowitz BA, Lenning J, Khetarpal N, Tran C, Wu JY, Berri AM, Dernay K, Haacke EM, Shafie-Khorassani F, Podolsky RH, Gant JC, Maimaiti S, Thibault O, Murphy GG, Bennett BM, et al. In vivo imaging of prodromal hippocampus CA1 subfield oxidative stress in models of Alzheimer disease and Angelman syndrome. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28592637 DOI: 10.1096/Fj.201700229R  0.638
2016 Frazier HN, Maimaiti S, Anderson KL, Brewer LD, Gant JC, Porter NM, Thibault O. Calcium's role as nuanced modulator of cellular physiology in the brain. Biochemical and Biophysical Research Communications. PMID 27553276 DOI: 10.1016/J.Bbrc.2016.08.105  0.652
2015 Gant JC, Chen KC, Kadish I, Blalock EM, Thibault O, Porter NM, Landfield PW. Reversal of Aging-Related Neuronal Ca2+ Dysregulation and Cognitive Impairment by Delivery of a Transgene Encoding FK506-Binding Protein 12.6/1b to the Hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 10878-87. PMID 26224869 DOI: 10.1523/Jneurosci.1248-15.2015  0.821
2015 Maimaiti S, Anderson KL, DeMoll C, Brewer LD, Rauh BA, Gant JC, Blalock EM, Porter NM, Thibault O. Intranasal Insulin Improves Age-Related Cognitive Deficits and Reverses Electrophysiological Correlates of Brain Aging. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 25659889 DOI: 10.1093/Gerona/Glu314  0.727
2014 Gant JC, Blalock EM, Chen KC, Kadish I, Porter NM, Norris CM, Thibault O, Landfield PW. FK506-binding protein 1b/12.6: a key to aging-related hippocampal Ca2+ dysregulation? European Journal of Pharmacology. 739: 74-82. PMID 24291098 DOI: 10.1016/J.Ejphar.2013.10.070  0.804
2011 Gant JC, Chen KC, Norris CM, Kadish I, Thibault O, Blalock EM, Porter NM, Landfield PW. Disrupting function of FK506-binding protein 1b/12.6 induces the Ca²+-dysregulation aging phenotype in hippocampal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 1693-703. PMID 21289178 DOI: 10.1523/Jneurosci.4805-10.2011  0.807
2010 Blalock EM, Phelps JT, Pancani T, Searcy JL, Anderson KL, Gant JC, Popovic J, Avdiushko MG, Cohen DA, Chen KC, Porter NM, Thibault O. Effects of long-term pioglitazone treatment on peripheral and central markers of aging. Plos One. 5: e10405. PMID 20454453 DOI: 10.1371/Journal.Pone.0010405  0.785
2009 Kadish I, Thibault O, Blalock EM, Chen KC, Gant JC, Porter NM, Landfield PW. Hippocampal and cognitive aging across the lifespan: a bioenergetic shift precedes and increased cholesterol trafficking parallels memory impairment. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1805-16. PMID 19211887 DOI: 10.1523/Jneurosci.4599-08.2009  0.777
2009 Gant JC, Thibault O, Blalock EM, Yang J, Bachstetter A, Kotick J, Schauwecker PE, Hauser KF, Smith GM, Mervis R, Li Y, Barnes GN. Decreased number of interneurons and increased seizures in neuropilin 2 deficient mice: implications for autism and epilepsy. Epilepsia. 50: 629-45. PMID 18657176 DOI: 10.1111/J.1528-1167.2008.01725.X  0.607
2009 Gant JC, Thibault O. Action potential throughput in aged rat hippocampal neurons: regulation by selective forms of hyperpolarization. Neurobiology of Aging. 30: 2053-64. PMID 18367293 DOI: 10.1016/J.Neurobiolaging.2008.02.006  0.684
2007 Thibault O, Gant JC, Landfield PW. Expansion of the calcium hypothesis of brain aging and Alzheimer's disease: minding the store. Aging Cell. 6: 307-17. PMID 17465978 DOI: 10.1111/J.1474-9726.2007.00295.X  0.793
2006 Gant JC, Sama MM, Landfield PW, Thibault O. Early and simultaneous emergence of multiple hippocampal biomarkers of aging is mediated by Ca2+-induced Ca2+ release. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 3482-90. PMID 16571755 DOI: 10.1523/Jneurosci.4171-05.2006  0.809
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