Year |
Citation |
Score |
2021 |
Paucar M, Ågren R, Li T, Lissmats S, Bergendal Å, Weinberg J, Nilsson D, Savichetva I, Sahlholm K, Nilsson J, Svenningsson P. V374A KCND3 Pathogenic Variant Associated With Paroxysmal Ataxia Exacerbations. Neurology. Genetics. 7: e546. PMID 33575485 DOI: 10.1212/NXG.0000000000000546 |
0.697 |
|
2020 |
Ågren R, Zeberg H, Maciej Stępniewski T, Free RB, Reilly SW, Luedtke RR, Århem P, Ciruela F, Sibley DR, Mach RH, Selent J, Nilsson J, Sahlholm K. A ligand with two modes of interaction with the dopamine D2 receptor - An induced-fit mechanism of insurmountable antagonism. Acs Chemical Neuroscience. PMID 32865974 DOI: 10.1021/Acschemneuro.0C00477 |
0.798 |
|
2019 |
Ågren R, Nilsson J, Århem P. Closed and open state dependent block of potassium channels cause opposing effects on excitability - a computational approach. Scientific Reports. 9: 8175. PMID 31160624 DOI: 10.1038/S41598-019-44564-X |
0.68 |
|
2018 |
Ågren R, Århem P, Nilsson J, Sahlholm K. The beta-arrestin-biased dopamine D2 receptor ligand, UNC9994, is a partial agonist at G-protein-mediated potassium channel activation. The International Journal of Neuropsychopharmacology. PMID 29986044 DOI: 10.1093/Ijnp/Pyy059 |
0.785 |
|
2018 |
Zeberg H, Nilsson J, Århem P. The Importance of the Dissociation Rate in Ion Channel Blocking. Frontiers in Cellular Neuroscience. 12: 33. PMID 29479308 DOI: 10.3389/Fncel.2018.00033 |
0.784 |
|
2018 |
Ågren R, Sahlholm K, Nilsson J, Århem P. Point mutation of a conserved aspartate, D69, in the muscarinic M2 receptor does not modify voltage-sensitive agonist potency. Biochemical and Biophysical Research Communications. PMID 29305262 DOI: 10.1016/J.Bbrc.2018.01.005 |
0.798 |
|
2016 |
Sahlholm K, Zeberg H, Nilsson J, Ögren SO, Fuxe K, Århem P. The fast-off hypothesis revisited: A functional kinetic study of antipsychotic antagonism of the dopamine D2 receptor. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 26811292 DOI: 10.1016/J.Euroneuro.2016.01.001 |
0.789 |
|
2015 |
Lyu C, Mulder J, Barde S, Sahlholm K, Zeberg H, Nilsson J, Århem P, Hökfelt T, Fried K, Shi TJ. G protein-gated inwardly rectifying potassium channel subunits 1 and 2 are down-regulated in rat dorsal root ganglion neurons and spinal cord after peripheral axotomy. Molecular Pain. 11: 44. PMID 26199148 DOI: 10.1186/S12990-015-0044-Z |
0.769 |
|
2014 |
Sahlholm K, Marcellino D, Nilsson J, Ögren SO, Fuxe K, Århem P. Typical and atypical antipsychotics do not differ markedly in their reversibility of antagonism of the dopamine D2 receptor. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 17: 149-55. PMID 24074141 DOI: 10.1017/S1461145713000801 |
0.779 |
|
2014 |
Sahlholm K, Zeberg H, Marcellino D, Nilsson J, Ogren S, Fuxe K, Arhem P. P.3.c.010 The fast-off hypothesis revisited: on-rates and reversibility of antipsychotic antagonism at the D2 receptor European Neuropsychopharmacology. 24: S520. DOI: 10.1016/S0924-977X(14)70833-8 |
0.772 |
|
2013 |
Shi TJ, Zhang MD, Zeberg H, Nilsson J, Grünler J, Liu SX, Xiang Q, Persson J, Fried KJ, Catrina SB, Watanabe M, Arhem P, Brismar K, Hökfelt TG. Coenzyme Q10 prevents peripheral neuropathy and attenuates neuron loss in the db-/db- mouse, a type 2 diabetes model. Proceedings of the National Academy of Sciences of the United States of America. 110: 690-5. PMID 23267110 DOI: 10.1073/Pnas.1220794110 |
0.703 |
|
2013 |
Nilsson J, Zeberg H, Madeja M, Arhem P. Local Anesthetics on Kv Channels - Closed State Binding of Bupivacaine? Biophysical Journal. 104: 126a. DOI: 10.1016/J.Bpj.2012.11.726 |
0.797 |
|
2013 |
Sahlholm K, Frisk S, Nilsson J, Marcellino D, Fuxe K, Ove Ögren S, Århem P. Novel Aspects of the Reversibility of the Antagonism at the Dopamine D2 Receptor by Antipsychotics Biophysical Journal. 104: 26a. DOI: 10.1016/J.Bpj.2012.11.183 |
0.787 |
|
2012 |
Sahlholm K, Nilsson J, Marcellino D, Fuxe K, Arhem P. Voltage sensitivities and deactivation kinetics of histamine H₃ and H₄ receptors. Biochimica Et Biophysica Acta. 1818: 3081-9. PMID 22885137 DOI: 10.1016/J.Bbamem.2012.07.027 |
0.784 |
|
2012 |
Sahlholm K, Frisk S, Marcellino D, Nilsson J, Fuxe K, Århem P. P.1.030 Antagonist dissociation from dopamine D2 receptors: studies using a time-resolved ion channel activation assay European Neuropsychopharmacology. 22: S29. DOI: 10.1016/S0924-977X(12)70031-7 |
0.794 |
|
2012 |
Nilsson J, Kempka M, Arhem P. The Action of the Neuroprotective Compound Riluzole on Kv Channels Biophysical Journal. 102: 134a. DOI: 10.1016/J.Bpj.2011.11.742 |
0.69 |
|
2012 |
Sahlholm K, Frisk S, Nilsson J, Marcellino D, Fuxe Peter Århem K. Dopamine D2 Receptor Antagonist Unbinding Rates Investigated using a Time-Resolved Ion Channel Activation Assay Biophysical Journal. 102: 517a. DOI: 10.1016/J.Bpj.2011.11.2829 |
0.743 |
|
2010 |
Marcellino D, Navarro G, Sahlholm K, Nilsson J, Agnati LF, Canela EI, LluÃs C, Ã…rhem P, Franco R, Fuxe K. Cocaine produces D2R-mediated conformational changes in the adenosine A(2A)R-dopamine D2R heteromer. Biochemical and Biophysical Research Communications. 394: 988-92. PMID 20307491 DOI: 10.1016/J.Bbrc.2010.03.104 |
0.733 |
|
2010 |
Sahlholm K, Marcellino D, Nilsson J, Fuxe K, Århem P. Agonist-Specific Effects of TM V Serine Mutations on Dopamine D2S Receptor Voltage-Sensitivity Biophysical Journal. 98: 290a. DOI: 10.1016/J.Bpj.2009.12.1581 |
0.795 |
|
2010 |
Nilsson J, Madeja M, Sahlholm K, Arhem P. Kv Channel Modulation: Closed State Block of Benzocaine But Not of Bupivacaine Biophysical Journal. 98: 213a. DOI: 10.1016/J.Bpj.2009.12.1149 |
0.797 |
|
2009 |
Sahlholm K, Marcellino D, Nilsson J, Fuxe K, Århem P. Differential Voltage-sensitivities Of Agonists At The Dopamine D2S Receptor Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.1986 |
0.748 |
|
2008 |
Sahlholm K, Marcellino D, Nilsson J, Fuxe K, Arhem P. Voltage-sensitivity at the human dopamine D2S receptor is agonist-specific. Biochemical and Biophysical Research Communications. 377: 1216-21. PMID 18983826 DOI: 10.1016/J.Bbrc.2008.10.117 |
0.8 |
|
2008 |
Nilsson J, Madeja M, Elinder F, Arhem P. Bupivacaine blocks N-type inactivating Kv channels in the open state: no allosteric effect on inactivation kinetics. Biophysical Journal. 95: 5138-52. PMID 18790854 DOI: 10.1529/Biophysj.108.130518 |
0.779 |
|
2008 |
Sahlholm K, Marcellino D, Nilsson J, Fuxe K, Arhem P. Differential voltage-sensitivity of D2-like dopamine receptors. Biochemical and Biophysical Research Communications. 374: 496-501. PMID 18652803 DOI: 10.1016/J.Bbrc.2008.07.052 |
0.787 |
|
2008 |
Sahlholm K, Nilsson J, Marcellino D, Fuxe K, Arhem P. Electrophysiology-based analysis of human histamine H(4) receptor pharmacology using GIRK channel coupling in Xenopus oocytes. European Journal of Pharmacology. 591: 52-8. PMID 18582456 DOI: 10.1016/J.Ejphar.2008.06.029 |
0.784 |
|
2008 |
Sahlholm K, Nilsson J, Marcellino D, Fuxe K, Arhem P. Voltage-dependence of the human dopamine D2 receptor. Synapse (New York, N.Y.). 62: 476-80. PMID 18361445 DOI: 10.1002/Syn.20509 |
0.8 |
|
2008 |
Klement G, Nilsson J, Arhem P, Elinder F. A tyrosine substitution in the cavity wall of a k channel induces an inverted inactivation. Biophysical Journal. 94: 3014-22. PMID 18192362 DOI: 10.1529/Biophysj.107.119842 |
0.806 |
|
2008 |
Århem P, Sahlholm K, Nilsson J. Mechanisms of Anaesthesia: A Role for Voltage-Gated K Channels? Anaesthesia Science. 117-127. DOI: 10.1002/9780470755297.ch9 |
0.766 |
|
2007 |
Elinder F, Nilsson J, Arhem P. On the opening of voltage-gated ion channels. Physiology & Behavior. 92: 1-7. PMID 17585963 DOI: 10.1016/J.Physbeh.2007.05.058 |
0.771 |
|
2007 |
Sahlholm K, Nilsson J, Marcellino D, Fuxe K, Arhem P. The human histamine H3 receptor couples to GIRK channels in Xenopus oocytes. European Journal of Pharmacology. 567: 206-10. PMID 17537431 DOI: 10.1016/J.Ejphar.2007.04.032 |
0.783 |
|
2007 |
Bränström R, Leibiger IB, Leibiger B, Klement G, Nilsson J, Arhem P, Aspinwall CA, Corkey BE, Larsson O, Berggren PO. Single residue (K332A) substitution in Kir6.2 abolishes the stimulatory effect of long-chain acyl-CoA esters: indications for a long-chain acyl-CoA ester binding motif. Diabetologia. 50: 1670-7. PMID 17522836 DOI: 10.1007/S00125-007-0697-X |
0.749 |
|
2005 |
Persson AS, Klement G, Almgren M, Sahlholm K, Nilsson J, Petersson S, Arhem P, Schalling M, Lavebratt C. A truncated Kv1.1 protein in the brain of the megencephaly mouse: expression and interaction. Bmc Neuroscience. 6: 65. PMID 16305740 DOI: 10.1186/1471-2202-6-65 |
0.763 |
|
2003 |
Petersson S, Persson AS, Johansen JE, Ingvar M, Nilsson J, Klement G, Arhem P, Schalling M, Lavebratt C. Truncation of the Shaker-like voltage-gated potassium channel, Kv1.1, causes megencephaly. The European Journal of Neuroscience. 18: 3231-40. PMID 14686897 DOI: 10.1111/J.1460-9568.2003.03044.X |
0.746 |
|
2003 |
Luzhkov VB, Nilsson J, Arhem P, Aqvist J. Computational modelling of the open-state Kv 1.5 ion channel block by bupivacaine. Biochimica Et Biophysica Acta. 1652: 35-51. PMID 14580995 DOI: 10.1016/J.Bbapap.2003.08.006 |
0.68 |
|
2003 |
Arhem P, Klement G, Nilsson J. Mechanisms of anesthesia: towards integrating network, cellular, and molecular level modeling. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: S40-7. PMID 12827143 DOI: 10.1038/Sj.Npp.1300142 |
0.761 |
|
2003 |
Nilsson J, Madeja M, Arhem P. Local anesthetic block of Kv channels: role of the S6 helix and the S5-S6 linker for bupivacaine action. Molecular Pharmacology. 63: 1417-29. PMID 12761353 DOI: 10.1124/Mol.63.6.1417 |
0.692 |
|
1998 |
Nilsson J, Elinder F, Arhem P. Mechanisms of bupivacaine action on Na+ and K+ channels in myelinated axons of Xenopus laevis. European Journal of Pharmacology. 360: 21-9. PMID 9845268 DOI: 10.1016/S0014-2999(98)00631-1 |
0.757 |
|
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