| Year |
Citation |
Score |
| 2022 |
Newman ZL, Bakshinskaya D, Schultz R, Kenny SJ, Moon S, Aghi K, Stanley C, Marnani N, Li R, Bleier J, Xu K, Isacoff EY. Determinants of synapse diversity revealed by super-resolution quantal transmission and active zone imaging. Nature Communications. 13: 229. PMID 35017509 DOI: 10.1038/s41467-021-27815-2 |
0.787 |
|
| 2021 |
Donthamsetti P, Winter N, Hoagland A, Stanley C, Visel M, Lammel S, Trauner D, Isacoff E. Cell specific photoswitchable agonist for reversible control of endogenous dopamine receptors. Nature Communications. 12: 4775. PMID 34362914 DOI: 10.1038/s41467-021-25003-w |
0.777 |
|
| 2020 |
Oldfield CS, Grossrubatscher I, Chávez M, Hoagland A, Huth AR, Carroll EC, Prendergast A, Qu T, Gallant JL, Wyart C, Isacoff EY. Experience, circuit dynamics and forebrain recruitment in larval zebrafish prey capture. Elife. 9. PMID 32985972 DOI: 10.7554/eLife.56619 |
0.765 |
|
| 2020 |
Mony L, Stroebel D, Isacoff EY. Dimer interaction in the Hv1 proton channel. Proceedings of the National Academy of Sciences of the United States of America. PMID 32788354 DOI: 10.1073/pnas.2010032117 |
0.403 |
|
| 2020 |
Li Z, Zhang Q, Chou SW, Newman Z, Turcotte R, Natan R, Dai Q, Isacoff EY, Ji N. Fast widefield imaging of neuronal structure and function with optical sectioning in vivo. Science Advances. 6: eaaz3870. PMID 32494711 DOI: 10.1126/Sciadv.Aaz3870 |
0.73 |
|
| 2020 |
Morstein J, Dacheux MA, Norman DD, Shemet A, Donthamsetti PC, Citir M, Frank J, Schultz C, Isacoff EY, Parrill AL, Tigyi GJ, Trauner D. Optical Control of Lysophosphatidic Acid Signaling. Journal of the American Chemical Society. PMID 32469525 DOI: 10.1021/Jacs.0C02154 |
0.342 |
|
| 2019 |
Habrian CH, Levitz J, Vyklicky V, Fu Z, Hoagland A, McCort-Tranchepain I, Acher F, Isacoff EY. Conformational pathway provides unique sensitivity to a synaptic mGluR. Nature Communications. 10: 5572. PMID 31804469 DOI: 10.1038/S41467-019-13407-8 |
0.799 |
|
| 2019 |
Donthamsetti PC, Broichhagen J, Vyklicky V, Stanley C, Fu Z, Visel M, Levitz JL, Javitch JA, Trauner D, Isacoff EY. Genetically Targeted Optical Control of an Endogenous G Protein-Coupled Receptor. Journal of the American Chemical Society. PMID 31291105 DOI: 10.1021/Jacs.9B02895 |
0.69 |
|
| 2019 |
Berry MH, Holt A, Salari A, Veit J, Visel M, Levitz J, Aghi K, Gaub BM, Sivyer B, Flannery JG, Isacoff EY. Restoration of high-sensitivity and adapting vision with a cone opsin. Nature Communications. 10: 1221. PMID 30874546 DOI: 10.1038/S41467-019-09124-X |
0.768 |
|
| 2018 |
Xiao T, Ackerman CM, Carroll EC, Jia S, Hoagland A, Chan J, Thai B, Liu CS, Isacoff EY, Chang CJ. Copper regulates rest-activity cycles through the locus coeruleus-norepinephrine system. Nature Chemical Biology. PMID 29867144 DOI: 10.1038/S41589-018-0062-Z |
0.766 |
|
| 2018 |
Berry MH, Holt A, Levitz J, Broichhagen J, Gaub BM, Visel M, Stanley C, Aghi K, Kim YJ, Cao K, Kramer RH, Trauner D, Flannery J, Isacoff EY. Author Correction: Restoration of patterned vision with an engineered photoactivatable G protein-coupled receptor. Nature Communications. 9: 1112. PMID 29535310 DOI: 10.1038/S41467-018-03585-2 |
0.762 |
|
| 2017 |
Berry MH, Holt A, Levitz J, Broichhagen J, Gaub BM, Visel M, Stanley C, Aghi K, Kim YJ, Trauner D, Flannery J, Isacoff EY. Restoration of patterned vision with an engineered photoactivatable G protein-coupled receptor. Nature Communications. 8: 1862. PMID 29192252 DOI: 10.1038/S41467-017-01990-7 |
0.783 |
|
| 2017 |
Donthamsetti P, Winter N, Schönberger M, Levitz J, Stanley C, Javitch JA, Isacoff EY, Trauner D. Optical Control of Dopamine Receptors Using a Photoswitchable Tethered Inverse Agonist. Journal of the American Chemical Society. PMID 29166564 DOI: 10.1021/Jacs.7B07659 |
0.663 |
|
| 2017 |
Pantoja C, Hoagland A, Carroll E, Schoppik D, Isacoff EY. Measuring Behavioral Individuality in the Acoustic Startle Behavior in Zebrafish. Bio-Protocol. 7. PMID 28752108 DOI: 10.21769/BioProtoc.2200 |
0.757 |
|
| 2017 |
Kienzler MA, Isacoff EY. Precise modulation of neuronal activity with synthetic photoswitchable ligands. Current Opinion in Neurobiology. PMID 28690101 DOI: 10.1016/J.Conb.2017.05.021 |
0.391 |
|
| 2017 |
Palty R, Fu Z, Isacoff EY. Sequential Steps of CRAC Channel Activation. Cell Reports. 19: 1929-1939. PMID 28564609 DOI: 10.1016/J.Celrep.2017.05.025 |
0.378 |
|
| 2017 |
Berlin S, Isacoff EY. Synapses in the spotlight with synthetic optogenetics. Embo Reports. PMID 28396573 DOI: 10.15252/embr.201744010 |
0.406 |
|
| 2017 |
Levitz J, Broichhagen J, Leippe P, Konrad D, Trauner D, Isacoff EY. Dual optical control and mechanistic insights into photoswitchable group II and III metabotropic glutamate receptors. Proceedings of the National Academy of Sciences of the United States of America. PMID 28396447 DOI: 10.1073/Pnas.1619652114 |
0.682 |
|
| 2017 |
Tomczak AP, Fernández-Trillo J, Bharill S, Papp F, Panyi G, Stühmer W, Isacoff EY, Pardo LA. A new mechanism of voltage-dependent gating exposed by KV10.1 channels interrupted between voltage sensor and pore. The Journal of General Physiology. PMID 28360219 DOI: 10.1085/Jgp.201611742 |
0.391 |
|
| 2017 |
Newman ZL, Hoagland A, Aghi K, Worden K, Levy SL, Son JH, Lee LP, Isacoff EY. Input-Specific Plasticity and Homeostasis at the Drosophila Larval Neuromuscular Junction. Neuron. PMID 28285823 DOI: 10.1016/J.Neuron.2017.02.028 |
0.772 |
|
| 2016 |
Barber DM, Schönberger M, Burgstaller J, Levitz J, Weaver CD, Isacoff EY, Baier H, Trauner D. Optical control of neuronal activity using a light-operated GIRK channel opener (LOGO). Chemical Science. 7: 2347-2352. PMID 28090283 DOI: 10.1039/C5Sc04084A |
0.718 |
|
| 2016 |
Levitz J, Habrian C, Bharill S, Fu Z, Vafabakhsh R, Isacoff EY. Mechanism of Assembly and Cooperativity of Homomeric and Heteromeric Metabotropic Glutamate Receptors. Neuron. PMID 27641494 DOI: 10.1016/J.Neuron.2016.08.036 |
0.691 |
|
| 2016 |
Pantoja C, Hoagland A, Carroll EC, Karalis V, Conner A, Isacoff EY. Neuromodulatory Regulation of Behavioral Individuality in Zebrafish. Neuron. PMID 27397519 DOI: 10.1016/J.Neuron.2016.06.016 |
0.778 |
|
| 2016 |
Chen Y, Bharill S, O'Hagan R, Isacoff EY, Chalfie M. MEC-10 and MEC-19 Reduce the Neurotoxicity of the MEC-4(d) DEG/ENaC Channel in Caenorhabditis elegans. G3 (Bethesda, Md.). 6: 1121-30. PMID 27172609 DOI: 10.1534/G3.115.023507 |
0.333 |
|
| 2016 |
Levitz J, Royal P, Comoglio Y, Wdziekonski B, Schaub S, Clemens DM, Isacoff EY, Sandoz G. Heterodimerization within the TREK channel subfamily produces a diverse family of highly regulated potassium channels. Proceedings of the National Academy of Sciences of the United States of America. PMID 27035963 DOI: 10.1073/Pnas.1522459113 |
0.802 |
|
| 2016 |
Chen Y, Bharill S, Altun Z, O'Hagan R, Coblitz B, Isacoff EY, Chalfie M. C. elegans paraoxonase-like proteins control the functional expression of DEG/ENaC mechanosensory proteins. Molecular Biology of the Cell. PMID 26941331 DOI: 10.1091/Mbc.E15-08-0561 |
0.353 |
|
| 2016 |
Berlin S, Szobota S, Reiner A, Carroll EC, Kienzler MA, Guyon A, Xiao T, Tauner D, Isacoff EY. A family of photoswitchable NMDA receptors. Elife. 5. PMID 26929991 DOI: 10.7554/Elife.12040 |
0.799 |
|
| 2016 |
Grimm SS, Isacoff EY. Allosteric substrate switching in a voltage-sensing lipid phosphatase. Nature Chemical Biology. PMID 26878552 DOI: 10.1038/nchembio.2022 |
0.325 |
|
| 2016 |
Levitz J, Popescu AT, Reiner A, Isacoff EY. A Toolkit for Orthogonal and in vivo Optical Manipulation of Ionotropic Glutamate Receptors. Frontiers in Molecular Neuroscience. 9: 2. PMID 26869877 DOI: 10.3389/Fnmol.2016.00002 |
0.769 |
|
| 2016 |
Barber DM, Schönberger M, Burgstaller J, Levitz J, Weaver CD, Isacoff EY, Baier H, Trauner D. Optical control of neuronal activity using a light-operated GIRK channel opener (LOGO) Chemical Science. 7: 2347-2352. DOI: 10.1039/c5sc04084a |
0.31 |
|
| 2016 |
Levitz J, Habrian C, Bharill S, Fu Z, Vafabakhsh R, Isacoff E. Optical Probing of Metabotropic Glutamate Receptors Biophysical Journal. 110: 532a. DOI: 10.1016/J.Bpj.2015.11.2846 |
0.379 |
|
| 2015 |
Broichhagen J, Damijonaitis A, Levitz J, Sokol KR, Leippe P, Konrad D, Isacoff EY, Trauner D. Orthogonal Optical Control of a G Protein-Coupled Receptor with a SNAP-Tethered Photochromic Ligand. Acs Central Science. 1: 383-93. PMID 27162996 DOI: 10.1021/Acscentsci.5B00260 |
0.679 |
|
| 2015 |
Palty R, Isacoff EY. Cooperative Binding of Stromal Interaction Molecule 1 (STIM1) to the N and C Termini of Calcium Release-Activated Calcium Modulator 1 (Orai1). The Journal of Biological Chemistry. PMID 26546674 DOI: 10.1074/Jbc.M115.685289 |
0.332 |
|
| 2015 |
Chen Y, Bharill S, Isacoff EY, Chalfie M. Subunit composition of a DEG/ENaC mechanosensory channel of Caenorhabditis elegans. Proceedings of the National Academy of Sciences of the United States of America. 112: 11690-5. PMID 26324944 DOI: 10.1073/Pnas.1515968112 |
0.401 |
|
| 2015 |
Vafabakhsh R, Levitz J, Isacoff EY. Conformational dynamics of a class C G-protein-coupled receptor. Nature. 524: 497-501. PMID 26258295 DOI: 10.1038/Nature14679 |
0.692 |
|
| 2015 |
Berlin S, Carroll EC, Newman ZL, Okada HO, Quinn CM, Kallman B, Rockwell NC, Martin SS, Lagarias JC, Isacoff EY. Photoactivatable genetically encoded calcium indicators for targeted neuronal imaging. Nature Methods. PMID 26167640 DOI: 10.1038/Nmeth.3480 |
0.746 |
|
| 2015 |
Palty R, Stanley C, Isacoff EY. Critical role for Orai1 C-terminal domain and TM4 in CRAC channel gating. Cell Research. 25: 963-80. PMID 26138675 DOI: 10.1038/Cr.2015.80 |
0.352 |
|
| 2015 |
Mony L, Berger TK, Isacoff EY. A specialized molecular motion opens the Hv1 voltage-gated proton channel. Nature Structural & Molecular Biology. 22: 283-90. PMID 25730777 DOI: 10.1038/Nsmb.2978 |
0.52 |
|
| 2015 |
Ball RW, Peled ES, Guerrero G, Isacoff EY. BMP signaling and microtubule organization regulate synaptic strength. Neuroscience. 291: 155-66. PMID 25681521 DOI: 10.1016/J.Neuroscience.2015.01.069 |
0.697 |
|
| 2015 |
Carroll EC, Berlin S, Levitz J, Kienzler MA, Yuan Z, Madsen D, Larsen DS, Isacoff EY. Two-photon brightness of azobenzene photoswitches designed for glutamate receptor optogenetics. Proceedings of the National Academy of Sciences of the United States of America. 112: E776-85. PMID 25653339 DOI: 10.1073/Pnas.1416942112 |
0.686 |
|
| 2015 |
Reiner A, Levitz J, Isacoff EY. Controlling ionotropic and metabotropic glutamate receptors with light: principles and potential. Current Opinion in Pharmacology. 20: 135-43. PMID 25573450 DOI: 10.1016/J.Coph.2014.12.008 |
0.757 |
|
| 2015 |
Berger TK, Isacoff EY. Fluorescent labeling for patch-clamp fluorometry (PCF) measurements of real-time protein motion in ion channels. Methods in Molecular Biology (Clifton, N.J.). 1266: 93-106. PMID 25560069 DOI: 10.1007/978-1-4939-2272-7_6 |
0.535 |
|
| 2015 |
Friedmann D, Hoagland A, Berlin S, Isacoff EY. A spinal opsin controls early neural activity and drives a behavioral light response. Current Biology : Cb. 25: 69-74. PMID 25484291 DOI: 10.1016/J.Cub.2014.10.055 |
0.789 |
|
| 2015 |
Berlin S, Szobota S, Reiner A, Carroll EC, Kienzler MA, Guyon A, Xiao T, Trauner D, Isacoff EY. Author response: A family of photoswitchable NMDA receptors Elife. DOI: 10.7554/Elife.12040.024 |
0.771 |
|
| 2015 |
Palty R, Stanley C, Isacoff E. STIM1 Binding to Both the N' and C' Termini of Orai1 is Critical for Gating of CRAC Channels Biophysical Journal. 108: 129a. DOI: 10.1016/J.Bpj.2014.11.719 |
0.354 |
|
| 2015 |
Comoglio Y, Joshua L, Kienzler M, Lesage F, Isacoff E, Sandoz G. Phospholipase D2 Specifically Regulates TREK Channels via Direct Interaction and Local Production of Phosphatidic Acid Biophysical Journal. 108. DOI: 10.1016/J.Bpj.2014.11.2380 |
0.701 |
|
| 2015 |
Levitz J, Vafabakhsh R, Bharill S, Bharill S, Isacoff EY. Assembly and Cooperativity of Metabotropic Glutamate Receptors Biophysical Journal. 108: 416a-417a. DOI: 10.1016/J.Bpj.2014.11.2282 |
0.365 |
|
| 2015 |
Vafabakhsh R, Levitz J, Isacoff EY. Confrontational Dynamics of a GPCR Revealed by Single Molecule FRET Biophysical Journal. 108: 3-9. DOI: 10.1016/J.Bpj.2014.11.1915 |
0.685 |
|
| 2014 |
Gaub BM, Berry MH, Holt AE, Reiner A, Kienzler MA, Dolgova N, Nikonov S, Aguirre GD, Beltran WA, Flannery JG, Isacoff EY. Restoration of visual function by expression of a light-gated mammalian ion channel in retinal ganglion cells or ON-bipolar cells. Proceedings of the National Academy of Sciences of the United States of America. 111: E5574-83. PMID 25489083 DOI: 10.1073/Pnas.1414162111 |
0.572 |
|
| 2014 |
Rullo A, Reiner A, Reiter A, Trauner D, Isacoff EY, Woolley GA. Long wavelength optical control of glutamate receptor ion channels using a tetra-ortho-substituted azobenzene derivative. Chemical Communications (Cambridge, England). 50: 14613-5. PMID 25311049 DOI: 10.1039/C4Cc06612J |
0.617 |
|
| 2014 |
Comoglio Y, Levitz J, Kienzler MA, Lesage F, Isacoff EY, Sandoz G. Phospholipase D2 specifically regulates TREK potassium channels via direct interaction and local production of phosphatidic acid. Proceedings of the National Academy of Sciences of the United States of America. 111: 13547-52. PMID 25197053 DOI: 10.1073/Pnas.1407160111 |
0.796 |
|
| 2014 |
Bharill S, Fu Z, Palty R, Isacoff EY. Stoichiometry and specific assembly of Best ion channels. Proceedings of the National Academy of Sciences of the United States of America. 111: 6491-6. PMID 24748110 DOI: 10.1073/Pnas.1400248111 |
0.394 |
|
| 2014 |
Reiner A, Isacoff EY. Photoswitching of cell surface receptors using tethered ligands. Methods in Molecular Biology (Clifton, N.J.). 1148: 45-68. PMID 24718794 DOI: 10.1007/978-1-4939-0470-9_4 |
0.575 |
|
| 2014 |
Reiner A, Isacoff EY. Tethered ligands reveal glutamate receptor desensitization depends on subunit occupancy. Nature Chemical Biology. 10: 273-80. PMID 24561661 DOI: 10.1038/Nchembio.1458 |
0.591 |
|
| 2014 |
Peled ES, Newman ZL, Isacoff EY. Evoked and spontaneous transmission favored by distinct sets of synapses. Current Biology : Cb. 24: 484-93. PMID 24560571 DOI: 10.1016/J.Cub.2014.01.022 |
0.734 |
|
| 2014 |
Reiner A, Isacoff EY. Probing the Gating of Ionotropic Glutamate Receptors with Tethered Photoswitchable Ligands Biophysical Journal. 106. DOI: 10.1016/J.Bpj.2013.11.217 |
0.593 |
|
| 2014 |
Kienzler M, Levitz J, Isacoff E. Expanding the Visible Light Photoswitch Library: A Red-Shifted, Fast-Relaxing Azobenzene Photoswitch for Reversible Activation of Metabotropic Glutamate Receptors Biophysical Journal. 106: 380a-381a. DOI: 10.1016/J.Bpj.2013.11.2154 |
0.702 |
|
| 2014 |
Levitz J, Bharill S, Vafabakhsh R, Isacoff EY. Optical Probing of Metabotropic Glutamate Receptor Assembly and Cooperativity Biophysical Journal. 106: 20a-21a. DOI: 10.1016/J.Bpj.2013.11.168 |
0.385 |
|
| 2014 |
Mony L, Berger TK, Isacoff EY. The Specialized Role of the S1 Transmembrane Segment in the Gating of the Hv1 Proton Channel Biophysical Journal. 106: 233a. DOI: 10.1016/J.Bpj.2013.11.1365 |
0.54 |
|
| 2014 |
Vafabakhsh R, Levitz J, Isacoff EY. The Activation Dynamics of Class C Gpcrs Revealed by Single Molecule FRET Biophysical Journal. 106: 194a. DOI: 10.1016/J.Bpj.2013.11.1149 |
0.689 |
|
| 2013 |
Isacoff EY, Jan LY, Minor DL. Conduits of life's spark: a perspective on ion channel research since the birth of neuron. Neuron. 80: 658-74. PMID 24183018 DOI: 10.1016/J.Neuron.2013.10.040 |
0.669 |
|
| 2013 |
Kienzler MA, Reiner A, Trautman E, Yoo S, Trauner D, Isacoff EY. A red-shifted, fast-relaxing azobenzene photoswitch for visible light control of an ionotropic glutamate receptor. Journal of the American Chemical Society. 135: 17683-6. PMID 24171511 DOI: 10.1021/Ja408104W |
0.574 |
|
| 2013 |
Reiner A, Isacoff EY. The Brain Prize 2013: the optogenetics revolution. Trends in Neurosciences. 36: 557-60. PMID 24054067 DOI: 10.1016/J.Tins.2013.08.005 |
0.489 |
|
| 2013 |
Reiner A, Levitz J, Isacoff E. Bringing optogenetics to the synapse. Neuron. 79: 209-10. PMID 23889927 DOI: 10.1016/J.Neuron.2013.07.009 |
0.735 |
|
| 2013 |
Patti J, Isacoff EY. Measuring membrane voltage with fluorescent proteins. Cold Spring Harbor Protocols. 2013: 606-13. PMID 23818671 DOI: 10.1101/pdb.top075804 |
0.364 |
|
| 2013 |
Kauwe G, Isacoff EY. Rapid feedback regulation of synaptic efficacy during high-frequency activity at the Drosophila larval neuromuscular junction. Proceedings of the National Academy of Sciences of the United States of America. 110: 9142-7. PMID 23674684 DOI: 10.1073/Pnas.1221314110 |
0.787 |
|
| 2013 |
Hastie P, Ulbrich MH, Wang HL, Arant RJ, Lau AG, Zhang Z, Isacoff EY, Chen L. AMPA receptor/TARP stoichiometry visualized by single-molecule subunit counting. Proceedings of the National Academy of Sciences of the United States of America. 110: 5163-8. PMID 23479622 DOI: 10.1073/Pnas.1218765110 |
0.776 |
|
| 2013 |
Levitz J, Pantoja C, Gaub B, Janovjak H, Reiner A, Hoagland A, Schoppik D, Kane B, Stawski P, Schier AF, Trauner D, Isacoff EY. Optical control of metabotropic glutamate receptors. Nature Neuroscience. 16: 507-16. PMID 23455609 DOI: 10.1038/Nn.3346 |
0.804 |
|
| 2013 |
Kienzler MA, Reiner A, Trauner D, Isacoff E. Synthesis and Characterization of a Red-Shifted, Fast Relaxing, Photoswitchable Tethered Ligand for use in Modified Glutamate Receptors Biophysical Journal. 104: 678a. DOI: 10.1016/J.Bpj.2012.11.3744 |
0.599 |
|
| 2013 |
Mony L, Berger TK, Isacoff EY. Gating of the Hv1 Proton Channel Biophysical Journal. 104: 276a. DOI: 10.1016/J.Bpj.2012.11.1546 |
0.554 |
|
| 2013 |
Reiner A, Isacoff EY. Fast Photoswitching of Tethered Ligands to Study Ionotropic Glutamate Receptor Activation and Desensitization Biophysical Journal. 104. DOI: 10.1016/J.Bpj.2012.11.1523 |
0.601 |
|
| 2013 |
Berger TK, Mony L, Isacoff EY. pH-Dependent Conformational Changes of the Voltage-Gated Proton Channel Recorded with Patch Clamp Fluorometry Biophysical Journal. 104: 207a. DOI: 10.1016/J.Bpj.2012.11.1170 |
0.531 |
|
| 2012 |
Yu Y, Ulbrich MH, Li MH, Dobbins S, Zhang WK, Tong L, Isacoff EY, Yang J. Molecular mechanism of the assembly of an acid-sensing receptor ion channel complex. Nature Communications. 3: 1252. PMID 23212381 DOI: 10.1038/Ncomms2257 |
0.749 |
|
| 2012 |
Sandoz G, Isacoff EY. [Optical remote control of native ion channels]. Mã©Decine Sciences : M/S. 28: 934-7. PMID 23171896 DOI: 10.1051/Medsci/20122811011 |
0.671 |
|
| 2012 |
Sandoz G, Levitz J, Kramer RH, Isacoff EY. Optical control of endogenous proteins with a photoswitchable conditional subunit reveals a role for TREK1 in GABA(B) signaling. Neuron. 74: 1005-14. PMID 22726831 DOI: 10.1016/J.Neuron.2012.04.026 |
0.789 |
|
| 2012 |
Liu L, Kohout SC, Xu Q, Müller S, Kimberlin CR, Isacoff EY, Minor DL. A glutamate switch controls voltage-sensitive phosphatase function. Nature Structural & Molecular Biology. 19: 633-41. PMID 22562138 DOI: 10.1038/Nsmb.2289 |
0.797 |
|
| 2012 |
Reiner A, Arant RJ, Isacoff EY. Assembly stoichiometry of the GluK2/GluK5 kainate receptor complex. Cell Reports. 1: 234-40. PMID 22509486 DOI: 10.1016/J.Celrep.2012.01.003 |
0.79 |
|
| 2012 |
Ahrens KF, Heider B, Lee H, Isacoff EY, Siegel RM. Two-photon scanning microscopy of in vivo sensory responses of cortical neurons genetically encoded with a fluorescent voltage sensor in rat. Frontiers in Neural Circuits. 6: 15. PMID 22461770 DOI: 10.3389/Fncir.2012.00015 |
0.796 |
|
| 2012 |
Li D, Hérault K, Isacoff EY, Oheim M, Ropert N. Optogenetic activation of LiGluR-expressing astrocytes evokes anion channel-mediated glutamate release. The Journal of Physiology. 590: 855-73. PMID 22219341 DOI: 10.1113/Jphysiol.2011.219345 |
0.34 |
|
| 2012 |
Warp E, Agarwal G, Wyart C, Friedmann D, Oldfield CS, Conner A, Del Bene F, Arrenberg AB, Baier H, Isacoff EY. Emergence of patterned activity in the developing zebrafish spinal cord. Current Biology : Cb. 22: 93-102. PMID 22197243 DOI: 10.1016/J.Cub.2011.12.002 |
0.76 |
|
| 2012 |
Reiner A, Isacoff EY. Activation of Ionotropic Glutamate Receptors using Tethered Photoswitchable Ligands Biophysical Journal. 102: 115. DOI: 10.1016/J.Bpj.2011.11.648 |
0.609 |
|
| 2012 |
Bharill S, Isacoff EY. Single Molecule Optical Determination of Bestrophin Stoichiometry Biophysical Journal. 102: 549a-550a. DOI: 10.1016/J.Bpj.2011.11.2998 |
0.345 |
|
| 2012 |
Levitz J, Gaub B, Janovjak H, Stawski P, Trauner D, Isacoff E. Optical Control of Metabotropic Glutamate Receptors for Probing of G Protein Signaling and Receptor Activation Mechanism Biophysical Journal. 102: 517a. DOI: 10.1016/J.Bpj.2011.11.2827 |
0.402 |
|
| 2012 |
Liu L, Kohout SC, Xu Q, Mueller S, Isacoff EY, Minor D. Internal Switch Gates Phosphatase Activity of VSP Biophysical Journal. 102: 36a-37a. DOI: 10.1016/J.Bpj.2011.11.226 |
0.797 |
|
| 2012 |
Yu Y, Ulbrich MH, Dobbins S, Li M, Zhang WK, Tong L, Isacoff EY, Yang J. Molecular and Structural Mechanism of the Assembly of an Acid-Sensing Receptor/Ion Channel Complex Biophysical Journal. 102: 345a. DOI: 10.1016/J.Bpj.2011.11.1889 |
0.748 |
|
| 2011 |
Berger TK, Isacoff EY. The pore of the voltage-gated proton channel. Neuron. 72: 991-1000. PMID 22196334 DOI: 10.1016/J.Neuron.2011.11.014 |
0.53 |
|
| 2011 |
Findeisen F, Tolia A, Arant R, Kim EY, Isacoff E, Minor DL. Calmodulin overexpression does not alter Cav1.2 function or oligomerization state. Channels (Austin, Tex.). 5: 320-4. PMID 21712653 DOI: 10.4161/Chan.5.4.16821 |
0.783 |
|
| 2011 |
Zhu J, Yu Y, Ulbrich MH, Li MH, Isacoff EY, Honig B, Yang J. Structural model of the TRPP2/PKD1 C-terminal coiled-coil complex produced by a combined computational and experimental approach. Proceedings of the National Academy of Sciences of the United States of America. 108: 10133-8. PMID 21642537 DOI: 10.1073/Pnas.1017669108 |
0.71 |
|
| 2011 |
Janovjak H, Sandoz G, Isacoff EY. A modern ionotropic glutamate receptor with a K(+) selectivity signature sequence. Nature Communications. 2: 232. PMID 21407198 DOI: 10.1038/Ncomms1231 |
0.702 |
|
| 2011 |
Agarwal G, Isacoff E. Specializations of a pheromonal glomerulus in the Drosophila olfactory system. Journal of Neurophysiology. 105: 1711-21. PMID 21289134 DOI: 10.1152/jn.00591.2010 |
0.46 |
|
| 2011 |
Sandoz G, Bell SC, Isacoff EY. Optical probing of a dynamic membrane interaction that regulates the TREK1 channel. Proceedings of the National Academy of Sciences of the United States of America. 108: 2605-10. PMID 21262820 DOI: 10.1073/Pnas.1015788108 |
0.758 |
|
| 2011 |
Abuin L, Bargeton B, Ulbrich MH, Isacoff EY, Kellenberger S, Benton R. Functional architecture of olfactory ionotropic glutamate receptors. Neuron. 69: 44-60. PMID 21220098 DOI: 10.1016/J.Neuron.2010.11.042 |
0.726 |
|
| 2011 |
Koprowski P, Grajkowski W, Isacoff EY, Kubalski A. Genetic screen for potassium leaky small mechanosensitive channels (MscS) in Escherichia coli: recognition of cytoplasmic β domain as a new gating element. The Journal of Biological Chemistry. 286: 877-88. PMID 20978126 DOI: 10.1074/jbc.M110.176131 |
0.374 |
|
| 2011 |
Nakajo K, Ulbrich MH, Kubo Y, Isacoff EY. Density-dependent changes of the stoichiometry of KCNQ1–KCNE1 ion channel complex revealed by direct subunit counting using single molecule imaging Neuroscience Research. 71: e205. DOI: 10.1016/j.neures.2011.07.886 |
0.71 |
|
| 2011 |
Zhu J, Yu Y, Ulbrich MH, Li M, Isacoff EY, Honig B, Yang J. A Structural Model of the TRPP2/PKD1 C-Terminal Coiled Coil Complex Obtained by a Combination of Computational and Experimental Approaches Biophysical Journal. 100: 106a. DOI: 10.1016/J.Bpj.2010.12.787 |
0.719 |
|
| 2011 |
Kohout SC, Liu L, Xu Q, Isacoff EY, Minor DL. Another Look at Ci-VSP Biophysical Journal. 100: 29a. DOI: 10.1016/J.Bpj.2010.12.361 |
0.815 |
|
| 2011 |
Reiner A, Isacoff EY. Mechanistic Studies on Ionotropic Glutamate Receptors Using Tethered Photoswitchable Ligands Biophysical Journal. 100. DOI: 10.1016/J.Bpj.2010.12.1677 |
0.622 |
|
| 2011 |
Levitz J, Gaub B, Janovjak H, Stawski P, Trauner D, Isacoff EY. Design and Application of a Light-Activated Metabotropic Glutamate Receptor for Optical Control of Intracellular Signaling Pathways Biophysical Journal. 100: 177a. DOI: 10.1016/J.Bpj.2010.12.1188 |
0.719 |
|
| 2011 |
Findeisen F, Tolia A, Arant R, Kim EY, Isacoff EY, Minor DL. Calmodulin overexpression does not alter Ca v1.2 function or oligomerization state Channels. 5. |
0.762 |
|
| 2010 |
Heider B, Nathanson JL, Isacoff EY, Callaway EM, Siegel RM. Two-photon imaging of calcium in virally transfected striate cortical neurons of behaving monkey. Plos One. 5: e13829. PMID 21079806 DOI: 10.1371/Journal.Pone.0013829 |
0.521 |
|
| 2010 |
Del Bene F, Wyart C, Robles E, Tran A, Looger L, Scott EK, Isacoff EY, Baier H. Filtering of visual information in the tectum by an identified neural circuit. Science (New York, N.Y.). 330: 669-73. PMID 21030657 DOI: 10.1126/Science.1192949 |
0.615 |
|
| 2010 |
Nakajo K, Ulbrich MH, Kubo Y, Isacoff EY. Stoichiometry of the KCNQ1 - KCNE1 ion channel complex. Proceedings of the National Academy of Sciences of the United States of America. 107: 18862-7. PMID 20962273 DOI: 10.1073/pnas.1010354107 |
0.727 |
|
| 2010 |
Kim EY, Rumpf CH, Van Petegem F, Arant RJ, Findeisen F, Cooley ES, Isacoff EY, Minor DL. Multiple C-terminal tail Ca(2+)/CaMs regulate Ca(V)1.2 function but do not mediate channel dimerization. The Embo Journal. 29: 3924-38. PMID 20953164 DOI: 10.1038/Emboj.2010.260 |
0.773 |
|
| 2010 |
Papagiakoumou E, Anselmi F, Bègue A, de Sars V, Glückstad J, Isacoff EY, Emiliani V. Scanless two-photon excitation of channelrhodopsin-2. Nature Methods. 7: 848-54. PMID 20852649 DOI: 10.1038/nmeth.1505 |
0.334 |
|
| 2010 |
Lee H, Dean C, Isacoff E. Alternative splicing of neuroligin regulates the rate of presynaptic differentiation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 11435-46. PMID 20739565 DOI: 10.1523/Jneurosci.2946-10.2010 |
0.781 |
|
| 2010 |
Schwarzer C, Wong S, Shi J, Matthes E, Illek B, Ianowski JP, Arant RJ, Isacoff E, Vais H, Foskett JK, Maiellaro I, Hofer AM, Machen TE. Pseudomonas aeruginosa Homoserine lactone activates store-operated cAMP and cystic fibrosis transmembrane regulator-dependent Cl- secretion by human airway epithelia. The Journal of Biological Chemistry. 285: 34850-63. PMID 20739289 DOI: 10.1074/Jbc.M110.167668 |
0.77 |
|
| 2010 |
Janovjak H, Szobota S, Wyart C, Trauner D, Isacoff EY. A light-gated, potassium-selective glutamate receptor for the optical inhibition of neuronal firing. Nature Neuroscience. 13: 1027-32. PMID 20581843 DOI: 10.1038/Nn.2589 |
0.813 |
|
| 2010 |
Kohout SC, Bell SC, Liu L, Xu Q, Minor DL, Isacoff EY. Electrochemical coupling in the voltage-dependent phosphatase Ci-VSP. Nature Chemical Biology. 6: 369-75. PMID 20364128 DOI: 10.1038/Nchembio.349 |
0.785 |
|
| 2010 |
Siegel MS, Isacoff EY. Green fluorescent proteins (GFPs) for measuring voltage. Cold Spring Harbor Protocols. 2010: pdb.top76. PMID 20360380 DOI: 10.1101/pdb.top76 |
0.35 |
|
| 2010 |
Szobota S, Isacoff EY. Optical control of neuronal activity. Annual Review of Biophysics. 39: 329-48. PMID 20192766 DOI: 10.1146/Annurev.Biophys.093008.131400 |
0.782 |
|
| 2010 |
Tombola F, Ulbrich MH, Kohout SC, Isacoff EY. The opening of the two pores of the Hv1 voltage-gated proton channel is tuned by cooperativity. Nature Structural & Molecular Biology. 17: 44-50. PMID 20023640 DOI: 10.1038/Nsmb.1738 |
0.811 |
|
| 2010 |
Kohout SC, Bell SC, Liu L, Xu Q, Minor DL, Isacoff EY. Correction: Corrigendum: Electrochemical coupling in the voltage-dependent phosphatase Ci-VSP Nature Chemical Biology. 6: 782-782. DOI: 10.1038/Nchembio1010-782A |
0.766 |
|
| 2010 |
Nakajo K, Ulbrich MH, Kubo Y, Isacoff E. Stoichiometry of KCNQ1-KCNE1 Ion Channel Complex is Flexible and Density-Dependent Biophysical Journal. 98: 136a-137a. DOI: 10.1016/J.BPJ.2009.12.737 |
0.73 |
|
| 2010 |
Kohout SC, Bell SC, Xu Q, Minor DL, Isacoff E. Does the Linker in Ci-VSP Function as a PI(4,5)P2 Binding Domain? Biophysical Journal. 98: 313a. DOI: 10.1016/J.Bpj.2009.12.1698 |
0.804 |
|
| 2010 |
Kim EY, Rumpf C, Van Petegem F, Arant R, Cooley ES, Isacoff EY, Minor DL. Biochemical and Functional Characterization of Crystallographic Ca2+/CaM-Cav1.2 A-C-IQ Complex Dimer Biophysical Journal. 98: 16a. DOI: 10.1016/J.Bpj.2009.12.097 |
0.802 |
|
| 2009 |
Tombola F, Ulbrich MH, Isacoff EY. Architecture and gating of Hv1 proton channels. The Journal of Physiology. 587: 5325-9. PMID 19915215 DOI: 10.1113/jphysiol.2009.180265 |
0.807 |
|
| 2009 |
Kubo Y, Isacoff EY. Dynamic aspects of functioning membrane proteins. The Journal of Physiology. 587: 5315-6. PMID 19915214 DOI: 10.1113/jphysiol.2009.182113 |
0.454 |
|
| 2009 |
Wyart C, Del Bene F, Warp E, Scott EK, Trauner D, Baier H, Isacoff EY. Optogenetic dissection of a behavioural module in the vertebrate spinal cord. Nature. 461: 407-10. PMID 19759620 DOI: 10.1038/Nature08323 |
0.765 |
|
| 2009 |
Yu Y, Ulbrich MH, Li MH, Buraei Z, Chen XZ, Ong AC, Tong L, Isacoff EY, Yang J. Structural and molecular basis of the assembly of the TRPP2/PKD1 complex. Proceedings of the National Academy of Sciences of the United States of America. 106: 11558-63. PMID 19556541 DOI: 10.1073/Pnas.0903684106 |
0.721 |
|
| 2009 |
Martos V, Bell SC, Santos E, Isacoff EY, Trauner D, de Mendoza J. Molecular recognition and self-assembly special feature: Calix[4]arene-based conical-shaped ligands for voltage-dependent potassium channels. Proceedings of the National Academy of Sciences of the United States of America. 106: 10482-6. PMID 19435843 DOI: 10.1073/Pnas.0813396106 |
0.601 |
|
| 2009 |
Numano R, Szobota S, Lau AY, Gorostiza P, Volgraf M, Roux B, Trauner D, Isacoff EY. Nanosculpting reversed wavelength sensitivity into a photoswitchable iGluR. Proceedings of the National Academy of Sciences of the United States of America. 106: 6814-9. PMID 19342491 DOI: 10.1016/J.Neures.2010.07.2065 |
0.792 |
|
| 2009 |
Nakajo K, Ulbrich M, Kubo Y, Isacoff E. 2TP2-04 Density-dependent changes in stoichiometry of KCNQ1 complex(The 47th Annual Meeting of the Biophysical Society of Japan) Seibutsu Butsuri. 49: S48. DOI: 10.2142/biophys.49.S48_3 |
0.656 |
|
| 2009 |
Janovjak H, Isacoff E. Design Of A Potassium Selective, Light-gated Glutamate Receptor Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.2524 |
0.439 |
|
| 2009 |
Szobota S, Numano R, Wyart C, Gorostiza P, Volgraf M, Fortin DL, Del Bene F, Scott EK, Kramer RH, Trauner D, Isacoff EY. Engineering light-gated glutamate receptors Biophysical Journal. 96: 489a. DOI: 10.1016/J.Bpj.2008.12.2523 |
0.801 |
|
| 2009 |
Jin L, Baker B, Cohen L, Roman C, Pieribone V, Pralle A, Isacoff E, Mealer R, Hughes T. Random Insertion of Split-can Venus into Kv1.4 Yields Voltage Sensitive Fluorescent Probes Biophysical Journal. 96: 403a. DOI: 10.1016/j.bpj.2008.12.2049 |
0.684 |
|
| 2009 |
Kohout SC, Bell SC, Isacoff EY. Probing Protein Motions and Function in Ci-VSP Biophysical Journal. 96: 370a. DOI: 10.1016/J.Bpj.2008.12.1991 |
0.795 |
|
| 2008 |
Marriott G, Mao S, Sakata T, Ran J, Jackson DK, Petchprayoon C, Gomez TJ, Warp E, Tulyathan O, Aaron HL, Isacoff EY, Yan Y. Optical lock-in detection imaging microscopy for contrast-enhanced imaging in living cells. Proceedings of the National Academy of Sciences of the United States of America. 105: 17789-94. PMID 19004775 DOI: 10.1073/Pnas.0808882105 |
0.763 |
|
| 2008 |
Kohout SC, Isacoff EY. To dislodge an enzyme from an ion channel, try steroids. Nature Chemical Biology. 4: 650-1. PMID 18936745 DOI: 10.1038/Nchembio1108-650 |
0.77 |
|
| 2008 |
Gorostiza P, Isacoff EY. Optical switches for remote and noninvasive control of cell signaling. Science (New York, N.Y.). 322: 395-9. PMID 18927384 DOI: 10.1126/science.1166022 |
0.302 |
|
| 2008 |
Gorostiza P, Isacoff EY. Nanoengineering ion channels for optical control. Physiology (Bethesda, Md.). 23: 238-47. PMID 18927200 DOI: 10.1152/physiol.00018.2008 |
0.337 |
|
| 2008 |
Ulbrich MH, Isacoff EY. Rules of engagement for NMDA receptor subunits. Proceedings of the National Academy of Sciences of the United States of America. 105: 14163-8. PMID 18779583 DOI: 10.1073/pnas.0802075105 |
0.71 |
|
| 2008 |
Baker BJ, Mutoh H, Dimitrov D, Akemann W, Perron A, Iwamoto Y, Jin L, Cohen LB, Isacoff EY, Pieribone VA, Hughes T, Knöpfel T. Genetically encoded fluorescent sensors of membrane potential. Brain Cell Biology. 36: 53-67. PMID 18679801 DOI: 10.1007/S11068-008-9026-7 |
0.328 |
|
| 2008 |
Pautot S, Wyart C, Isacoff EY. Colloid-guided assembly of oriented 3D neuronal networks. Nature Methods. 5: 735-40. PMID 18641658 DOI: 10.1038/Nmeth.1236 |
0.631 |
|
| 2008 |
Tombola F, Ulbrich MH, Isacoff EY. The voltage-gated proton channel Hv1 has two pores, each controlled by one voltage sensor. Neuron. 58: 546-56. PMID 18498736 DOI: 10.1016/j.neuron.2008.03.026 |
0.808 |
|
| 2008 |
Kohout SC, Ulbrich MH, Bell SC, Isacoff EY. Subunit organization and functional transitions in Ci-VSP. Nature Structural & Molecular Biology. 15: 106-8. PMID 18084307 DOI: 10.1038/Nsmb1320 |
0.803 |
|
| 2008 |
Wang S, Wang Y, Szobota S, Volgraf M, Liu Z, Sun C, Trauner D, Isacoff EY, Zhang X. All optical platform for parallel and spatiotemporal control of neuronal activity Optics Infobase Conference Papers. DOI: 10.1364/Fio.2008.Ftul4 |
0.771 |
|
| 2007 |
Wang S, Szobota S, Wang Y, Volgraf M, Liu Z, Sun C, Trauner D, Isacoff EY, Zhang X. All optical interface for parallel, remote, and spatiotemporal control of neuronal activity. Nano Letters. 7: 3859-63. PMID 18034506 DOI: 10.1021/Nl072783T |
0.767 |
|
| 2007 |
Stowers RS, Isacoff EY. Drosophila huntingtin-interacting protein 14 is a presynaptic protein required for photoreceptor synaptic transmission and expression of the palmitoylated proteins synaptosome-associated protein 25 and cysteine string protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 12874-83. PMID 18032660 DOI: 10.1523/JNEUROSCI.2464-07.2007 |
0.321 |
|
| 2007 |
Pathak MM, Yarov-Yarovoy V, Agarwal G, Roux B, Barth P, Kohout S, Tombola F, Isacoff EY. Closing in on the resting state of the Shaker K(+) channel. Neuron. 56: 124-40. PMID 17920020 DOI: 10.1016/J.Neuron.2007.09.023 |
0.811 |
|
| 2007 |
Gorostiza P, Isacoff E. Optical switches and triggers for the manipulation of ion channels and pores. Molecular Biosystems. 3: 686-704. PMID 17882331 DOI: 10.1039/b710287a |
0.399 |
|
| 2007 |
Gorostiza P, Volgraf M, Numano R, Szobota S, Trauner D, Isacoff EY. Mechanisms of photoswitch conjugation and light activation of an ionotropic glutamate receptor. Proceedings of the National Academy of Sciences of the United States of America. 104: 10865-70. PMID 17578923 DOI: 10.1073/Pnas.0701274104 |
0.79 |
|
| 2007 |
Szobota S, Gorostiza P, Del Bene F, Wyart C, Fortin DL, Kolstad KD, Tulyathan O, Volgraf M, Numano R, Aaron HL, Scott EK, Kramer RH, Flannery J, Baier H, Trauner D, ... Isacoff EY, et al. Remote control of neuronal activity with a light-gated glutamate receptor. Neuron. 54: 535-45. PMID 17521567 DOI: 10.1016/J.Neuron.2007.05.010 |
0.787 |
|
| 2007 |
Miller EW, Tulyathan O, Tulyanthan O, Isacoff EY, Chang CJ. Molecular imaging of hydrogen peroxide produced for cell signaling. Nature Chemical Biology. 3: 263-7. PMID 17401379 DOI: 10.1038/Nchembio871 |
0.771 |
|
| 2007 |
Ulbrich MH, Isacoff EY. Subunit counting in membrane-bound proteins. Nature Methods. 4: 319-21. PMID 17369835 DOI: 10.1038/nmeth1024 |
0.697 |
|
| 2007 |
Volgraf M, Gorostiza P, Szobota S, Helix MR, Isacoff EY, Trauner D. Reversibly caged glutamate: a photochromic agonist of ionotropic glutamate receptors. Journal of the American Chemical Society. 129: 260-1. PMID 17212390 DOI: 10.1021/Ja067269O |
0.756 |
|
| 2007 |
Tombola F, Pathak MM, Gorostiza P, Isacoff EY. The twisted ion-permeation pathway of a resting voltage-sensing domain. Nature. 445: 546-9. PMID 17187057 DOI: 10.1038/nature05396 |
0.77 |
|
| 2007 |
Baker BJ, Lee H, Pieribone VA, Cohen LB, Isacoff EY, Knopfel T, Kosmidis EK. Three fluorescent protein voltage sensors exhibit low plasma membrane expression in mammalian cells. Journal of Neuroscience Methods. 161: 32-8. PMID 17126911 DOI: 10.1016/J.Jneumeth.2006.10.005 |
0.798 |
|
| 2007 |
Miller EW, Tulyathan O, Isacoff EY, Chang CJ. Corrigendum: Molecular imaging of hydrogen peroxide produced for cell signaling Nature Chemical Biology. 3: 349-349. DOI: 10.1038/Nchembio0607-349 |
0.76 |
|
| 2006 |
Tombola F, Pathak MM, Isacoff EY. How does voltage open an ion channel? Annual Review of Cell and Developmental Biology. 22: 23-52. PMID 16704338 DOI: 10.1146/annurev.cellbio.21.020404.145837 |
0.777 |
|
| 2006 |
Kaláb P, Pralle A, Isacoff EY, Heald R, Weis K. Analysis of a RanGTP-regulated gradient in mitotic somatic cells. Nature. 440: 697-701. PMID 16572176 DOI: 10.1038/Nature04589 |
0.629 |
|
| 2006 |
Volgraf M, Gorostiza P, Numano R, Kramer RH, Isacoff EY, Trauner D. Allosteric control of an ionotropic glutamate receptor with an optical switch. Nature Chemical Biology. 2: 47-52. PMID 16408092 DOI: 10.1038/Nchembio756 |
0.426 |
|
| 2006 |
Zeng L, Miller EW, Pralle A, Isacoff EY, Chang CJ. A selective turn-on fluorescent sensor for imaging copper in living cells. Journal of the American Chemical Society. 128: 10-1. PMID 16390096 DOI: 10.1021/Ja055064U |
0.633 |
|
| 2005 |
Gorostiza P, Tombola F, Verdaguer A, Smith SB, Bustamante C, Isacoff EY. Molecular handles for the mechanical manipulation of single-membrane proteins in living cells. Ieee Transactions On Nanobioscience. 4: 269-76. PMID 16433292 DOI: 10.1109/Tnb.2005.859552 |
0.667 |
|
| 2005 |
Pautot S, Lee H, Isacoff EY, Groves JT. Neuronal synapse interaction reconstituted between live cells and supported lipid bilayers. Nature Chemical Biology. 1: 283-9. PMID 16408058 DOI: 10.1038/Nchembio737 |
0.784 |
|
| 2005 |
Tombola F, Pathak MM, Isacoff EY. How far will you go to sense voltage? Neuron. 48: 719-25. PMID 16337910 DOI: 10.1016/j.neuron.2005.11.024 |
0.769 |
|
| 2005 |
Miller EW, Albers AE, Pralle A, Isacoff EY, Chang CJ. Boronate-based fluorescent probes for imaging cellular hydrogen peroxide. Journal of the American Chemical Society. 127: 16652-9. PMID 16305254 DOI: 10.1021/Ja054474F |
0.64 |
|
| 2005 |
Baksh MM, Dean C, Pautot S, DeMaria S, Isacoff E, Groves JT. Neuronal activation by GPI-linked neuroligin-1 displayed in synthetic lipid bilayer membranes. Langmuir : the Acs Journal of Surfaces and Colloids. 21: 10693-8. PMID 16262338 DOI: 10.1021/La051243D |
0.626 |
|
| 2005 |
Guerrero G, Reiff DF, Rieff DF, Agarwal G, Ball RW, Borst A, Goodman CS, Isacoff EY. Heterogeneity in synaptic transmission along a Drosophila larval motor axon. Nature Neuroscience. 8: 1188-96. PMID 16116446 DOI: 10.1038/Nn1526 |
0.78 |
|
| 2005 |
Gandhi CS, Isacoff EY. Shedding light on membrane proteins. Trends in Neurosciences. 28: 472-9. PMID 16043238 DOI: 10.1016/J.Tins.2005.07.005 |
0.741 |
|
| 2005 |
Reiff DF, Ihring A, Guerrero G, Isacoff EY, Joesch M, Nakai J, Borst A. In vivo performance of genetically encoded indicators of neural activity in flies. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 4766-78. PMID 15888652 DOI: 10.1523/JNEUROSCI.4900-04.2005 |
0.301 |
|
| 2005 |
Tombola F, Pathak MM, Isacoff EY. Voltage-sensing arginines in a potassium channel permeate and occlude cation-selective pores. Neuron. 45: 379-88. PMID 15694325 DOI: 10.1016/j.neuron.2004.12.047 |
0.762 |
|
| 2005 |
Cohen BE, Pralle A, Yao X, Swaminath G, Gandhi CS, Jan YN, Kobilka BK, Isacoff EY, Jan LY. A fluorescent probe designed for studying protein conformational change. Proceedings of the National Academy of Sciences of the United States of America. 102: 965-70. PMID 15657131 DOI: 10.1073/Pnas.0409469102 |
0.79 |
|
| 2005 |
Pathak M, Kurtz L, Tombola F, Isacoff E. The cooperative voltage sensor motion that gates a potassium channel. The Journal of General Physiology. 125: 57-69. PMID 15623895 DOI: 10.1085/jgp.200409197 |
0.775 |
|
| 2005 |
Guerrero G, Rieff DF, Agarwal G, Ball RW, Borst A, Goodman CS, Isacoff EY. Erratum: Heterogeneity in synaptic transmission along a Drosophila larval motor axon Nature Neuroscience. 8: 1411-1411. DOI: 10.1038/nn1005-1411a |
0.747 |
|
| 2004 |
Chang MC, Pralle A, Isacoff EY, Chang CJ. A selective, cell-permeable optical probe for hydrogen peroxide in living cells. Journal of the American Chemical Society. 126: 15392-3. PMID 15563161 DOI: 10.1021/Ja0441716 |
0.631 |
|
| 2004 |
Banghart M, Borges K, Isacoff E, Trauner D, Kramer RH. Light-activated ion channels for remote control of neuronal firing. Nature Neuroscience. 7: 1381-6. PMID 15558062 DOI: 10.1038/Nn1356 |
0.417 |
|
| 2003 |
Gandhi CS, Clark E, Loots E, Pralle A, Isacoff EY. The orientation and molecular movement of a k(+) channel voltage-sensing domain. Neuron. 40: 515-25. PMID 14642276 DOI: 10.1016/S0896-6273(03)00646-9 |
0.799 |
|
| 2003 |
Gradl SN, Felix JP, Isacoff EY, Garcia ML, Trauner D. Protein surface recognition by rational design: nanomolar ligands for potassium channels. Journal of the American Chemical Society. 125: 12668-9. PMID 14558789 DOI: 10.1021/Ja036155Z |
0.328 |
|
| 2003 |
Dean C, Scholl FG, Choih J, DeMaria S, Berger J, Isacoff E, Scheiffele P. Neurexin mediates the assembly of presynaptic terminals. Nature Neuroscience. 6: 708-16. PMID 12796785 DOI: 10.1038/Nn1074 |
0.616 |
|
| 2003 |
Sonnleitner A, Isacoff E. Single ion channel imaging. Methods in Enzymology. 361: 304-19. PMID 12624917 DOI: 10.1016/S0076-6879(03)61016-5 |
0.393 |
|
| 2003 |
Gandhi CS, Isacoff EY. How Do Voltage-Gated Channels Sense the Membrane Potential? Handbook of Cell Signaling. 1: 209-214. DOI: 10.1016/B978-012124546-7/50396-X |
0.741 |
|
| 2002 |
Guerrero G, Siegel MS, Roska B, Loots E, Isacoff EY. Tuning FlaSh: redesign of the dynamics, voltage range, and color of the genetically encoded optical sensor of membrane potential. Biophysical Journal. 83: 3607-18. PMID 12496128 DOI: 10.1016/S0006-3495(02)75361-7 |
0.809 |
|
| 2002 |
Schönherr R, Mannuzzu LM, Isacoff EY, Heinemann SH. Conformational switch between slow and fast gating modes: allosteric regulation of voltage sensor mobility in the EAG K+ channel. Neuron. 35: 935-49. PMID 12372287 DOI: 10.1016/S0896-6273(02)00869-3 |
0.35 |
|
| 2002 |
Gandhi CS, Isacoff EY. Molecular models of voltage sensing. The Journal of General Physiology. 120: 455-63. PMID 12356848 DOI: 10.1085/Jgp.20028678 |
0.744 |
|
| 2002 |
Sonnleitner A, Mannuzzu LM, Terakawa S, Isacoff EY. Structural rearrangements in single ion channels detected optically in living cells. Proceedings of the National Academy of Sciences of the United States of America. 99: 12759-64. PMID 12228726 DOI: 10.1073/pnas.192261499 |
0.408 |
|
| 2001 |
Guerrero G, Isacoff EY. Genetically encoded optical sensors of neuronal activity and cellular function. Current Opinion in Neurobiology. 11: 601-7. PMID 11595495 DOI: 10.1016/S0959-4388(00)00256-7 |
0.339 |
|
| 2000 |
Loots E, Isacoff EY. Molecular coupling of S4 to a K(+) channel's slow inactivation gate. The Journal of General Physiology. 116: 623-36. PMID 11055991 DOI: 10.1085/Jgp.116.5.623 |
0.804 |
|
| 2000 |
Gandhi CS, Loots E, Isacoff EY. Reconstructing voltage sensor-pore interaction from a fluorescence scan of a voltage-gated K+ channel. Neuron. 27: 585-95. PMID 11055440 DOI: 10.1016/S0896-6273(00)00068-4 |
0.808 |
|
| 2000 |
Siegel MS, Isacoff EY. Green fluorescent protein-based sensors for detecting signal transduction and monitoring ion channel function. Methods in Enzymology. 327: 249-59. PMID 11044988 DOI: 10.1016/S0076-6879(00)27281-9 |
0.357 |
|
| 2000 |
Mannuzzu LM, Isacoff EY. Independence and cooperativity in rearrangements of a potassium channel voltage sensor revealed by single subunit fluorescence. The Journal of General Physiology. 115: 257-68. PMID 10694254 DOI: 10.1085/jgp.115.3.257 |
0.376 |
|
| 1999 |
Glauner KS, Mannuzzu LM, Gandhi CS, Isacoff EY. Spectroscopic mapping of voltage sensor movement in the Shaker potassium channel. Nature. 402: 813-7. PMID 10617202 DOI: 10.1038/45561 |
0.77 |
|
| 1999 |
Zito K, Parnas D, Fetter RD, Isacoff EY, Goodman CS. Watching a synapse grow: noninvasive confocal imaging of synaptic growth in Drosophila. Neuron. 22: 719-29. PMID 10230792 DOI: 10.1016/S0896-6273(00)80731-X |
0.742 |
|
| 1998 |
Loots E, Isacoff EY. Protein rearrangements underlying slow inactivation of the Shaker K+ channel. The Journal of General Physiology. 112: 377-89. PMID 9758858 DOI: 10.1085/Jgp.112.4.377 |
0.812 |
|
| 1998 |
Baker OS, Larsson HP, Mannuzzu LM, Isacoff EY. Three transmembrane conformations and sequence-dependent displacement of the S4 domain in shaker K+ channel gating. Neuron. 20: 1283-94. PMID 9655514 DOI: 10.1016/S0896-6273(00)80507-3 |
0.791 |
|
| 1998 |
Harris RE, Larsson HP, Isacoff EY. A permanent ion binding site located between two gates of the Shaker K+ channel. Biophysical Journal. 74: 1808-20. PMID 9545043 DOI: 10.1016/S0006-3495(98)77891-9 |
0.58 |
|
| 1998 |
Terakawa S, Feller MB, Mannuzzu LM, Isacoff EY. Single fluorophore visualization of ion channel gating by evanescence microscopy Neuroscience Research. 31: S60. DOI: 10.1016/S0168-0102(98)81818-X |
0.623 |
|
| 1997 |
Zito K, Fetter RD, Goodman CS, Isacoff EY. Synaptic clustering of Fascilin II and Shaker: essential targeting sequences and role of Dlg. Neuron. 19: 1007-16. PMID 9390515 DOI: 10.1016/S0896-6273(00)80393-1 |
0.749 |
|
| 1997 |
Siegel MS, Isacoff EY. A genetically encoded optical probe of membrane voltage. Neuron. 19: 735-41. PMID 9354320 DOI: 10.1016/S0896-6273(00)80955-1 |
0.374 |
|
| 1996 |
Harris RE, Isacoff EY. Hydrophobic mutations alter the movement of Mg2+ in the pore of voltage-gated potassium channels. Biophysical Journal. 71: 209-19. PMID 8804604 DOI: 10.1016/S0006-3495(96)79217-2 |
0.522 |
|
| 1996 |
Larsson HP, Baker OS, Dhillon DS, Isacoff EY. Transmembrane movement of the shaker K+ channel S4. Neuron. 16: 387-97. PMID 8789953 DOI: 10.1016/S0896-6273(00)80056-2 |
0.784 |
|
| 1996 |
Mannuzzu LM, Moronne MM, Isacoff EY. Direct physical measure of conformational rearrangement underlying potassium channel gating. Science (New York, N.Y.). 271: 213-6. PMID 8539623 DOI: 10.1126/Science.271.5247.373 |
0.408 |
|
| 1993 |
Li M, Isacoff E, Jan YN, Jan LY. Assembly of potassium channels. Annals of the New York Academy of Sciences. 707: 51-9. PMID 9137541 DOI: 10.1111/j.1749-6632.1993.tb38041.x |
0.521 |
|
| 1993 |
Isacoff EY, Jan YN, Jan LY. Molecular basis of K+ channel inactivation gating. Exs. 63: 338-51. PMID 8380732 DOI: 10.1007/978-3-0348-7265-2_18 |
0.571 |
|
| 1992 |
Baldwin TJ, Isacoff E, Li M, Lopez GA, Sheng M, Tsaur ML, Yan YN, Jan LY. Elucidation of biophysical and biological properties of voltage-gated potassium channels. Cold Spring Harbor Symposia On Quantitative Biology. 57: 491-9. PMID 1339685 DOI: 10.1101/Sqb.1992.057.01.054 |
0.545 |
|
| 1991 |
Isacoff EY, Jan YN, Jan LY. Putative receptor for the cytoplasmic inactivation gate in the Shaker K+ channel. Nature. 353: 86-90. PMID 1881453 DOI: 10.1038/353086a0 |
0.551 |
|
| 1990 |
Isacoff E, Papazian D, Timpe L, Jan YN, Jan LY. Molecular studies of voltage-gated potassium channels. Cold Spring Harbor Symposia On Quantitative Biology. 55: 9-17. PMID 2132867 DOI: 10.1101/Sqb.1990.055.01.004 |
0.558 |
|
| 1990 |
Isacoff EY, Jan YN, Jan LY. Evidence for the formation of heteromultimeric potassium channels in Xenopus oocytes. Nature. 345: 530-4. PMID 2112229 DOI: 10.1038/345530a0 |
0.537 |
|
| 1988 |
Birks RI, Isacoff EY. Burst-patterned stimulation promotes nicotinic transmission in isolated perfused rat sympathetic ganglia. The Journal of Physiology. 402: 515-32. PMID 2907049 DOI: 10.1113/Jphysiol.1988.Sp017218 |
0.694 |
|
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