Sandra K. Weller - Publications

Affiliations: 
University of Connecticut, Storrs, CT, United States 
Area:
Molecular Biology, Biochemistry, Microbiology Biology

123 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Wright LR, Wright DL, Weller SK. Viral Nucleases from Herpesviruses and Coronavirus in Recombination and Proofreading: Potential Targets for Antiviral Drug Discovery. Viruses. 14. PMID 35891537 DOI: 10.3390/v14071557  0.39
2022 DiScipio KA, Weerasooriya S, Szczepaniak R, Hazeen A, Wright LR, Wright DL, Weller SK. Two-Metal Ion-Dependent Enzymes as Potential Antiviral Targets in Human Herpesviruses. Mbio. e0322621. PMID 35073739 DOI: 10.1128/mbio.03226-21  0.316
2021 Weller SK, Deluca NA. New model integrates innate responses, PML-NB formation, epigenetic control and reactivation from latency. Embo Reports. e53496. PMID 34313382 DOI: 10.15252/embr.202153496  0.328
2020 Taylor W, Camilleri E, Craft DL, Korza G, Rocha Granados M, Peterson J, Szczpaniak R, Weller SK, Moeller R, Douki T, Mok WWK, Setlow P. DNA damage Kills Bacterial Spores and Cells Exposed to 222 nm UV Radiation. Applied and Environmental Microbiology. PMID 32033948 DOI: 10.1128/Aem.03039-19  0.43
2020 Weerasooriya S, DiScipio KA, Peterson J, Weller SK. The Herpes Simplex Viruses Utilize a Recombination‐Dependent Replication Mechanism to Replicate Viral Genomes The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04857  0.499
2019 Adlakha M, Livingston CM, Bezsonova I, Weller SK. The HSV-1 immediate early protein ICP22 is a functional mimic of a cellular J-protein. Journal of Virology. PMID 31748398 DOI: 10.1128/Jvi.01564-19  0.497
2019 Weerasooriya S, DiScipio KA, Darwish AS, Bai P, Weller SK. Herpes simplex virus 1 ICP8 mutant lacking annealing activity is deficient for viral DNA replication. Proceedings of the National Academy of Sciences of the United States of America. 116: 1033-1042. PMID 30598436 DOI: 10.1073/Pnas.1817642116  0.69
2018 Wight DJ, Wallaschek N, Sanyal A, Weller SK, Flamand L, Kaufer BB. Viral Proteins U41 and U70 of Human Herpesvirus 6A Are Dispensable for Telomere Integration. Viruses. 10. PMID 30469324 DOI: 10.3390/V10110656  0.439
2017 Grady LM, Szczepaniak R, Murelli RP, Masaoka T, Le Grice SFJ, Wright DL, Weller SK. The exonuclease activity of HSV-1 UL12 is required for the production of viral DNA that can be packaged to produce infectious virus. Journal of Virology. PMID 28956767 DOI: 10.1128/Jvi.01380-17  0.637
2017 Bermek O, Weller SK, Griffith JD. The UL8 subunit of the helicase/primase complex of herpes simplex virus promotes DNA annealing and has a high affinity for replication forks. The Journal of Biological Chemistry. PMID 28743747 DOI: 10.1074/Jbc.M117.799064  0.63
2016 Lou DI, Kim ET, Meyerson NR, Pancholi NJ, Mohni KN, Enard D, Petrov DA, Weller SK, Weitzman MD, Sawyer SL. An Intrinsically Disordered Region of the DNA Repair Protein Nbs1 Is a Species-Specific Barrier to Herpes Simplex Virus 1 in Primates. Cell Host & Microbe. 20: 178-188. PMID 27512903 DOI: 10.1016/J.Chom.2016.07.003  0.817
2015 Darwish AS, Grady LM, Bai P, Weller SK. ICP8 Filament Formation Is Essential for Replication Compartment Formation during Herpes Simplex Virus Infection. Journal of Virology. 90: 2561-70. PMID 26676794 DOI: 10.1128/Jvi.02854-15  0.621
2015 Pozhidaeva AK, Mohni KN, Dhe-Paganon S, Arrowsmith CH, Weller SK, Korzhnev DM, Bezsonova I. Structural Characterization of Interaction between Human Ubiquitin-specific Protease 7 and Immediate-Early Protein ICP0 of Herpes Simplex Virus-1. The Journal of Biological Chemistry. 290: 22907-18. PMID 26224631 DOI: 10.1074/Jbc.M115.664805  0.801
2015 Smith S, Weller SK. HSV-I and the cellular DNA damage response. Future Virology. 10: 383-397. PMID 26213561 DOI: 10.2217/Fvl.15.18  0.581
2015 Albright BS, Kosinski A, Szczepaniak R, Cook EA, Stow ND, Conway JF, Weller SK. The putative herpes simplex virus 1 chaperone protein UL32 modulates disulfide bond formation during infection. Journal of Virology. 89: 443-53. PMID 25320327 DOI: 10.1128/Jvi.01913-14  0.651
2014 Weller SK, Sawitzke JA. Recombination promoted by DNA viruses: phage λ to herpes simplex virus. Annual Review of Microbiology. 68: 237-58. PMID 25002096 DOI: 10.1146/Annurev-Micro-091313-103424  0.611
2014 Smith S, Reuven N, Mohni KN, Schumacher AJ, Weller SK. Structure of the herpes simplex virus 1 genome: manipulation of nicks and gaps can abrogate infectivity and alter the cellular DNA damage response. Journal of Virology. 88: 10146-56. PMID 24965466 DOI: 10.1128/Jvi.01723-14  0.819
2014 Grady LM, Bai P, Weller SK. HSV-1 protein expression using recombinant baculoviruses. Methods in Molecular Biology (Clifton, N.J.). 1144: 293-304. PMID 24671692 DOI: 10.1007/978-1-4939-0428-0_20  0.486
2013 Mohni KN, Smith S, Dee AR, Schumacher AJ, Weller SK. Herpes simplex virus type 1 single strand DNA binding protein and helicase/primase complex disable cellular ATR signaling. Plos Pathogens. 9: e1003652. PMID 24098119 DOI: 10.1371/Journal.Ppat.1003652  0.839
2013 Weller SK, Kuchta RD. The DNA helicase-primase complex as a target for herpes viral infection. Expert Opinion On Therapeutic Targets. 17: 1119-32. PMID 23930666 DOI: 10.1517/14728222.2013.827663  0.466
2013 Mohni KN, Dee AR, Smith S, Schumacher AJ, Weller SK. Efficient herpes simplex virus 1 replication requires cellular ATR pathway proteins. Journal of Virology. 87: 531-42. PMID 23097436 DOI: 10.1128/Jvi.02504-12  0.856
2012 Weller SK, Coen DM. Herpes simplex viruses: mechanisms of DNA replication. Cold Spring Harbor Perspectives in Biology. 4: a013011. PMID 22952399 DOI: 10.1101/Cshperspect.A013011  0.637
2012 Schumacher AJ, Mohni KN, Kan Y, Hendrickson EA, Stark JM, Weller SK. The HSV-1 exonuclease, UL12, stimulates recombination by a single strand annealing mechanism. Plos Pathogens. 8: e1002862. PMID 22912580 DOI: 10.1371/Journal.Ppat.1002862  0.851
2011 Mohni KN, Mastrocola AS, Bai P, Weller SK, Heinen CD. DNA mismatch repair proteins are required for efficient herpes simplex virus 1 replication. Journal of Virology. 85: 12241-53. PMID 21957315 DOI: 10.1128/Jvi.05487-11  0.853
2011 Szczepaniak R, Nellissery J, Jadwin JA, Makhov AM, Kosinski A, Conway JF, Weller SK. Disulfide bond formation contributes to herpes simplex virus capsid stability and retention of pentons. Journal of Virology. 85: 8625-34. PMID 21697480 DOI: 10.1128/Jvi.00214-11  0.496
2011 Albright BS, Nellissery J, Szczepaniak R, Weller SK. Disulfide bond formation in the herpes simplex virus 1 UL6 protein is required for portal ring formation and genome encapsidation. Journal of Virology. 85: 8616-24. PMID 21593161 DOI: 10.1128/Jvi.00123-11  0.442
2011 Chen Y, Bai P, Mackay S, Korza G, Carson JH, Kuchta RD, Weller SK. Herpes simplex virus type 1 helicase-primase: DNA binding and consequent protein oligomerization and primase activation. Journal of Virology. 85: 968-78. PMID 21068246 DOI: 10.1128/Jvi.01690-10  0.553
2010 Weller SK. Herpes simplex virus reorganizes the cellular DNA repair and protein quality control machinery. Plos Pathogens. 6: e1001105. PMID 21124825 DOI: 10.1371/Journal.Ppat.1001105  0.621
2010 Balasubramanian N, Bai P, Buchek G, Korza G, Weller SK. Physical interaction between the herpes simplex virus type 1 exonuclease, UL12, and the DNA double-strand break-sensing MRN complex. Journal of Virology. 84: 12504-14. PMID 20943970 DOI: 10.1128/Jvi.01506-10  0.775
2010 Mohni KN, Livingston CM, Cortez D, Weller SK. ATR and ATRIP are recruited to herpes simplex virus type 1 replication compartments even though ATR signaling is disabled. Journal of Virology. 84: 12152-64. PMID 20861269 DOI: 10.1128/Jvi.01643-10  0.837
2010 Nicolas A, Alazard-Dany N, Biollay C, Arata L, Jolinon N, Kuhn L, Ferro M, Weller SK, Epstein AL, Salvetti A, Greco A. Identification of rep-associated factors in herpes simplex virus type 1-induced adeno-associated virus type 2 replication compartments. Journal of Virology. 84: 8871-87. PMID 20573815 DOI: 10.1128/Jvi.00725-10  0.623
2010 Bastian TW, Livingston CM, Weller SK, Rice SA. Herpes simplex virus type 1 immediate-early protein ICP22 is required for VICE domain formation during productive viral infection. Journal of Virology. 84: 2384-94. PMID 20032172 DOI: 10.1128/Jvi.01686-09  0.544
2010 Weller SK. DNA Virus Replication Topley and Wilson's Microbiology and Microbial Infections. DOI: 10.1002/9780470688618.Taw0216  0.585
2009 Livingston CM, Ifrim MF, Cowan AE, Weller SK. Virus-Induced Chaperone-Enriched (VICE) domains function as nuclear protein quality control centers during HSV-1 infection. Plos Pathogens. 5: e1000619. PMID 19816571 DOI: 10.1371/Journal.Ppat.1000619  0.484
2009 Faili A, Stary A, Delbos F, Weller S, Aoufouchi S, Sarasin A, Weill J, Reynaud C. A Backup Role of DNA Polymerase κ in Ig Gene Hypermutation Only Takes Place in the Complete Absence of DNA Polymerase η Journal of Immunology. 182: 6353-6359. PMID 19414788 DOI: 10.4049/Jimmunol.0900177  0.424
2009 Pauklin S, Burkert JS, Martin J, Osman F, Weller S, Boulton SJ, Whitby MC, Petersen-Mahrt SK. Alternative induction of meiotic recombination from single-base lesions of DNA deaminases. Genetics. 182: 41-54. PMID 19237686 DOI: 10.1534/Genetics.109.101683  0.459
2009 Weller SK. Herpesvirus genome replication Viral Genome Replication. 249-265. DOI: 10.1007/b135974_13  0.474
2008 Livingston CM, DeLuca NA, Wilkinson DE, Weller SK. Oligomerization of ICP4 and rearrangement of heat shock proteins may be important for herpes simplex virus type 1 prereplicative site formation. Journal of Virology. 82: 6324-36. PMID 18434395 DOI: 10.1128/Jvi.00455-08  0.638
2007 Chattopadhyay S, Weller SK. Direct interaction between the N- and C-terminal portions of the herpes simplex virus type 1 origin binding protein UL9 implies the formation of a head-to-tail dimer. Journal of Virology. 81: 13659-67. PMID 17942532 DOI: 10.1128/Jvi.01204-07  0.486
2007 Iwahori S, Shirata N, Kawaguchi Y, Weller SK, Sato Y, Kudoh A, Nakayama S, Isomura H, Tsurumi T. Enhanced phosphorylation of transcription factor sp1 in response to herpes simplex virus type 1 infection is dependent on the ataxia telangiectasia-mutated protein. Journal of Virology. 81: 9653-64. PMID 17609267 DOI: 10.1128/Jvi.00568-07  0.498
2007 Nellissery JK, Szczepaniak R, Lamberti C, Weller SK. A putative leucine zipper within the herpes simplex virus type 1 UL6 protein is required for portal ring formation. Journal of Virology. 81: 8868-77. PMID 17581990 DOI: 10.1128/Jvi.00739-07  0.528
2007 Chen Y, Livingston CM, Carrington-Lawrence SD, Bai P, Weller SK. A mutation in the human herpes simplex virus type 1 UL52 zinc finger motif results in defective primase activity but can recruit viral polymerase and support viral replication efficiently. Journal of Virology. 81: 8742-51. PMID 17553899 DOI: 10.1128/Jvi.00174-07  0.86
2007 Saffran HA, Pare JM, Corcoran JA, Weller SK, Smiley JR. Herpes simplex virus eliminates host mitochondrial DNA. Embo Reports. 8: 188-93. PMID 17186027 DOI: 10.1038/Sj.Embor.7400878  0.518
2006 Wilkinson DE, Weller SK. Herpes simplex virus type I disrupts the ATR-dependent DNA-damage response during lytic infection. Journal of Cell Science. 119: 2695-703. PMID 16757521 DOI: 10.1242/Jcs.02981  0.647
2006 Chattopadhyay S, Chen Y, Weller SK. The two helicases of herpes simplex virus type 1 (HSV-1). Frontiers in Bioscience : a Journal and Virtual Library. 11: 2213-23. PMID 16720308 DOI: 10.2741/1964  0.657
2006 Chattopadhyay S, Weller SK. DNA binding activity of the herpes simplex virus type 1 origin binding protein, UL9, can be modulated by sequences in the N terminus: correlation between transdominance and DNA binding. Journal of Virology. 80: 4491-500. PMID 16611909 DOI: 10.1128/Jvi.80.9.4491-4500.2006  0.56
2006 Weller SK, Coen DM. 33 Herpes Simplex Virus Cold Spring Harbor Monograph Archive. 47: 663-686. DOI: 10.1101/087969766.47.663  0.59
2005 Weller S, Reynaud C, Weill J. Splenic marginal zone B cells in humans: where do they mutate their Ig receptor? European Journal of Immunology. 35: 2789-2792. PMID 16180256 DOI: 10.1002/Eji.200535446  0.306
2005 Pierce AT, DeSalvo J, Foster TP, Kosinski A, Weller SK, Halford WP. Beta interferon and gamma interferon synergize to block viral DNA and virion synthesis in herpes simplex virus-infected cells. The Journal of General Virology. 86: 2421-32. PMID 16099899 DOI: 10.1099/Vir.0.80979-0  0.45
2005 Burch AD, Weller SK. Herpes simplex virus type 1 DNA polymerase requires the mammalian chaperone hsp90 for proper localization to the nucleus. Journal of Virology. 79: 10740-9. PMID 16051866 DOI: 10.1128/Jvi.79.16.10740-10749.2005  0.587
2005 Reuven NB, Weller SK. Herpes simplex virus type 1 single-strand DNA binding protein ICP8 enhances the nuclease activity of the UL12 alkaline nuclease by increasing its processivity. Journal of Virology. 79: 9356-8. PMID 15994834 DOI: 10.1128/Jvi.79.14.9356-9358.2005  0.562
2005 Chen Y, Carrington-Lawrence SD, Bai P, Weller SK. Mutations in the putative zinc-binding motif of UL52 demonstrate a complex interdependence between the UL5 and UL52 subunits of the human herpes simplex virus type 1 helicase/primase complex. Journal of Virology. 79: 9088-96. PMID 15994803 DOI: 10.1128/Jvi.79.14.9088-9096.2005  0.843
2005 Wilkinson DE, Weller SK. Inhibition of the herpes simplex virus type 1 DNA polymerase induces hyperphosphorylation of replication protein A and its accumulation at S-phase-specific sites of DNA damage during infection. Journal of Virology. 79: 7162-71. PMID 15890955 DOI: 10.1128/Jvi.79.11.7162-7171.2005  0.607
2004 Reuven NB, Willcox S, Griffith JD, Weller SK. Catalysis of strand exchange by the HSV-1 UL12 and ICP8 proteins: potent ICP8 recombinase activity is revealed upon resection of dsDNA substrate by nuclease. Journal of Molecular Biology. 342: 57-71. PMID 15313607 DOI: 10.1016/J.Jmb.2004.07.012  0.544
2004 Burch AD, Weller SK. Nuclear sequestration of cellular chaperone and proteasomal machinery during herpes simplex virus type 1 infection. Journal of Virology. 78: 7175-85. PMID 15194794 DOI: 10.1128/Jvi.78.13.7175-7185.2004  0.58
2004 Wilkinson DE, Weller SK. Recruitment of cellular recombination and repair proteins to sites of herpes simplex virus type 1 DNA replication is dependent on the composition of viral proteins within prereplicative sites and correlates with the induction of the DNA damage response. Journal of Virology. 78: 4783-96. PMID 15078960 DOI: 10.1128/Jvi.78.9.4783-4796.2004  0.662
2004 Reuven NB, Antoku S, Weller SK. The UL12.5 gene product of herpes simplex virus type 1 exhibits nuclease and strand exchange activities but does not localize to the nucleus. Journal of Virology. 78: 4599-608. PMID 15078942 DOI: 10.1128/Jvi.78.9.4599-4608.2004  0.639
2004 Stracker TH, Cassell GD, Ward P, Loo YM, van Breukelen B, Carrington-Lawrence SD, Hamatake RK, van der Vliet PC, Weller SK, Melendy T, Weitzman MD. The Rep protein of adeno-associated virus type 2 interacts with single-stranded DNA-binding proteins that enhance viral replication. Journal of Virology. 78: 441-53. PMID 14671124 DOI: 10.1128/Jvi.78.1.441-453.2004  0.855
2003 Wilkinson DE, Weller SK. The role of DNA recombination in herpes simplex virus DNA replication. Iubmb Life. 55: 451-8. PMID 14609200 DOI: 10.1080/15216540310001612237  0.65
2003 Marintcheva B, Weller SK. Existence of transdominant and potentiating mutants of UL9, the herpes simplex virus type 1 origin-binding protein, suggests that levels of UL9 protein may be regulated during infection. Journal of Virology. 77: 9639-51. PMID 12915576 DOI: 10.1128/Jvi.77.17.9639-9651.2003  0.841
2003 Przech AJ, Yu D, Weller SK. Point mutations in exon I of the herpes simplex virus putative terminase subunit, UL15, indicate that the most conserved residues are essential for cleavage and packaging. Journal of Virology. 77: 9613-21. PMID 12915573 DOI: 10.1128/Jvi.77.17.9613-9621.2003  0.803
2003 Reuven NB, Staire AE, Myers RS, Weller SK. The herpes simplex virus type 1 alkaline nuclease and single-stranded DNA binding protein mediate strand exchange in vitro. Journal of Virology. 77: 7425-33. PMID 12805441 DOI: 10.1128/Jvi.77.13.7425-7433.2003  0.606
2003 Weller S, Faili A, Aoufouchi S, Guéranger Q, Braun M, Reynaud C, Weill J. Hypermutation in human B cells in vivo and in vitro Annals of the New York Academy of Sciences. 987: 158-165. PMID 12727635 DOI: 10.1111/J.1749-6632.2003.Tb06044.X  0.354
2003 Carrington-Lawrence SD, Weller SK. Recruitment of polymerase to herpes simplex virus type 1 replication foci in cells expressing mutant primase (UL52) proteins. Journal of Virology. 77: 4237-47. PMID 12634381 DOI: 10.1128/Jvi.77.7.4237-4247.2003  0.855
2003 Marintcheva B, Weller SK. Helicase motif Ia is involved in single-strand DNA-binding and helicase activities of the herpes simplex virus type 1 origin-binding protein, UL9. Journal of Virology. 77: 2477-88. PMID 12551986 DOI: 10.1128/Jvi.77.4.2477-2488.2003  0.819
2002 Martinez R, Goldstein JN, Weller SK. The product of the UL12.5 gene of herpes simplex virus type 1 is not essential for lytic viral growth and is not specifically associated with capsids. Virology. 298: 248-57. PMID 12127788 DOI: 10.1006/Viro.2002.1444  0.546
2002 Weill J, Bertocci B, Faili A, Aoufouchi S, Frey S, Smet AD, Storck S, Dahan A, Delbos F, Weller S, Flatter E, Reynaud C. Ig gene hypermutation: a mechanism is due. Advances in Immunology. 80: 183-202. PMID 12078481 DOI: 10.1016/S0065-2776(02)80015-3  0.352
2001 Marintcheva B, Weller SK. A tale of two HSV-1 helicases: Roles of phage and animal virus helicases in DNA replication and recombination Progress in Nucleic Acid Research and Molecular Biology. 70: 77-118. PMID 11642367 DOI: 10.1016/S0079-6603(01)70014-1  0.84
2001 Newcomb WW, Juhas RM, Thomsen DR, Homa FL, Burch AD, Weller SK, Brown JC. The UL6 gene product forms the portal for entry of DNA into the herpes simplex virus capsid. Journal of Virology. 75: 10923-32. PMID 11602732 DOI: 10.1128/Jvi.75.22.10923-10932.2001  0.59
2001 Biswas N, Weller SK. The UL5 and UL52 Subunits of the Herpes Simplex Virus Type 1 Helicase-Primase Subcomplex Exhibit a Complex Interdependence for DNA Binding Journal of Biological Chemistry. 276: 17610-17619. PMID 11278618 DOI: 10.1074/Jbc.M010107200  0.56
2001 Burkham J, Coen DM, Hwang CB, Weller SK. Interactions of herpes simplex virus type 1 with ND10 and recruitment of PML to replication compartments. Journal of Virology. 75: 2353-67. PMID 11160739 DOI: 10.1128/Jvi.75.5.2353-2367.2001  0.828
2001 Sheaffer AK, Newcomb WW, Gao M, Yu D, Weller SK, Brown JC, Tenney DJ. Herpes simplex virus DNA cleavage and packaging proteins associate with the procapsid prior to its maturation. Journal of Virology. 75: 687-98. PMID 11134282 DOI: 10.1128/Jvi.75.2.687-698.2001  0.628
2001 Marintcheva B, Weller SK. Residues within the Conserved Helicase Motifs of UL9, the Origin-binding Protein of Herpes Simplex Virus-1, Are Essential for Helicase Activity but Not for Dimerization or Origin Binding Activity Journal of Biological Chemistry. 276: 6605-6615. PMID 11062243 DOI: 10.1074/Jbc.M007743200  0.842
2000 Sheaffer AK, Newcomb WW, Brown JC, Gao M, Weller SK, Tenney DJ. Evidence for controlled incorporation of herpes simplex virus type 1 UL26 protease into capsids. Journal of Virology. 74: 6838-48. PMID 10888623 DOI: 10.1128/Jvi.74.15.6838-6848.2000  0.594
2000 Newcomb WW, Trus BL, Cheng N, Steven AC, Sheaffer AK, Tenney DJ, Weller SK, Brown JC. Isolation of herpes simplex virus procapsids from cells infected with a protease-deficient mutant virus. Journal of Virology. 74: 1663-73. PMID 10644336 DOI: 10.1128/Jvi.74.4.1663-1673.2000  0.573
1999 Biswas N, Weller SK. A mutation in the C-terminal putative Zn2+ finger motif of UL52 severely affects the biochemical activities of the HSV-1 helicase-primase subcomplex Journal of Biological Chemistry. 274: 8068-8076. PMID 10075707 DOI: 10.1074/Jbc.274.12.8068  0.606
1998 Burkham J, Coen DM, Weller SK. ND10 protein PML is recruited to herpes simplex virus type 1 prereplicative sites and replication compartments in the presence of viral DNA polymerase. Journal of Virology. 72: 10100-7. PMID 9811750 DOI: 10.1128/Jvi.72.12.10100-10107.1998  0.848
1998 Gao M, Robertson BJ, McCann PJ, O'Boyle DR, Weller SK, Newcomb WW, Brown JC, Weinheimer SP. Functional conservations of the alkaline nuclease of herpes simplex type 1 and human cytomegalovirus. Virology. 249: 460-70. PMID 9791036 DOI: 10.1006/Viro.1998.9344  0.59
1998 Goldstein JN, Weller SK. In vitro processing of herpes simplex virus type 1 DNA replication intermediates by the viral alkaline nuclease, UL12 Journal of Virology. 72: 8772-8781. PMID 9765421 DOI: 10.1128/Jvi.72.11.8772-8781.1998  0.568
1998 Dong Y, Weller SK. Herpes simplex virus type 1 cleavage and packaging proteins UL15 and UL28 are associated with B but not C capsids during packaging Journal of Virology. 72: 7428-7439. PMID 9696839 DOI: 10.1128/Jvi.72.9.7428-7439.1998  0.614
1998 Goldstein JN, Weller SK. The exonuclease activity of HSV-1 UL12 is required for in vivo function Virology. 244: 442-457. PMID 9601512 DOI: 10.1006/Viro.1998.9129  0.545
1998 Yu D, Weller SK. Genetic analysis of the UL15 gene locus for the putative terminase of herpes simplex virus type 1 Virology. 243: 32-44. PMID 9527913 DOI: 10.1006/Viro.1998.9041  0.628
1998 Lamberti C, Weller SK. The herpes simplex virus type 1 cleavage/packaging protein, UL32, is involved in efficient localization of capsids to replication compartments Journal of Virology. 72: 2463-2473. PMID 9499108 DOI: 10.1128/Jvi.72.3.2463-2473.1998  0.675
1997 Lukonis CJ, Burkham J, Weller SK. Herpes simplex virus type 1 prereplicative sites are a heterogeneous population: only a subset are likely to be precursors to replication compartments. Journal of Virology. 71: 4771-81. PMID 9151871 DOI: 10.1128/Jvi.71.6.4771-4781.1997  0.841
1997 Bronstein JC, Weller SK, Weber PC. The product of the UL12.5 gene of herpes simplex virus type 1 is a capsid-associated nuclease Journal of Virology. 71: 3039-3047. PMID 9060664 DOI: 10.1128/Jvi.71.4.3039-3047.1997  0.578
1997 Yu D, Sheaffer AK, Tenney DJ, Weller SK. Characterization of ICP6::lacZ insertion mutants of the UL15 gene of herpes simplex virus type 1 reveals the translation of two proteins Journal of Virology. 71: 2656-2665. PMID 9060618 DOI: 10.1128/Jvi.71.4.2656-2665.1997  0.625
1997 Lukonis CJ, Weller SK. Formation of herpes simplex virus type 1 replication compartments by transfection: Requirements and localization to nuclear domain 10 Journal of Virology. 71: 2390-2399. PMID 9032376 DOI: 10.1128/Jvi.71.3.2390-2399.1997  0.679
1997 Graves-Woodward KL, Gottlieb J, Challberg MD, Weller SK. Biochemical analyses of mutations in the HSV-1 helicase-primase that alter ATP hydrolysis, DNA unwinding, and coupling between hydrolysis and unwinding. The Journal of Biological Chemistry. 272: 4623-30. PMID 9020191 DOI: 10.1074/Jbc.272.7.4623  0.55
1996 Lamberti C, Weller SK. The herpes simplex virus type 1 UL6 protein is essential for cleavage and packaging but not for genomic inversion Virology. 226: 403-407. PMID 8955060 DOI: 10.1006/Viro.1996.0668  0.567
1996 Malik AK, Weller SK. Use of transdominant mutants of the origin-binding protein (UL9) of herpes simplex virus type 1 to define functional domains Journal of Virology. 70: 7859-7866. PMID 8892908 DOI: 10.1128/Jvi.70.11.7859-7866.1996  0.597
1996 Malik AK, Shao L, Shanley JD, Weller SK. Intracellular localization of the herpes simplex virus type-1 origin binding protein, UL9 Virology. 224: 380-389. PMID 8874499 DOI: 10.1006/Viro.1996.0545  0.582
1996 Lukonis CJ, Weller SK. The herpes simplex virus type 1 transactivator ICP0 mediates aberrant intracellular localization of the viral helicase/primase complex subunits Virology. 220: 495-501. PMID 8669135 DOI: 10.1006/Viro.1996.0338  0.607
1996 Graves-Woodward KL, Weller SK. Replacement of Gly815 in helicase motif V alters the single-stranded DNA-dependent ATPase activity of the herpes simplex virus type 1 helicase-primase Journal of Biological Chemistry. 271: 13629-13635. PMID 8662872 DOI: 10.1074/Jbc.271.23.13629  0.647
1996 Martinez R, Sarisky RT, Weber PC, Weller SK. Herpes simplex virus type 1 alkaline nuclease is required for efficient processing of viral DNA replication intermediates Journal of Virology. 70: 2075-2085. PMID 8642627 DOI: 10.1128/Jvi.70.4.2075-2085.1996  0.64
1996 Lukonis CJ, Weller SK. Characterization of nuclear structures in cells infected with herpes simplex virus type 1 in the absence of viral DNA replication Journal of Virology. 70: 1751-1758. PMID 8627697 DOI: 10.1128/Jvi.70.3.1751-1758.1996  0.685
1996 Martinez R, Shao L, Bronstein JC, Weber PC, Weller SK. The product of a 1.9-kb mRNA which overlaps the HSV-1 alkaline nuclease gene (UL12) cannot relieve the growth defects of a null mutant Virology. 215: 152-164. PMID 8560762 DOI: 10.1006/Viro.1996.0018  0.471
1993 Shao L, Rapp LM, Weller SK. Herpes simplex virus 1 alkaline nuclease is required for efficient egress of capsids from the nucleus. Virology. 196: 146-62. PMID 8395111 DOI: 10.1006/Viro.1993.1463  0.64
1992 Martinez R, Shao L, Weller SK. The conserved helicase motifs of the herpes simplex virus type 1 origin-binding protein UL9 are important for function Journal of Virology. 66: 6735-6746. PMID 1328687 DOI: 10.1128/Jvi.66.11.6735-6746.1992  0.636
1992 Malik AK, Martinez R, Muncy L, Carmichael EP, Weller SK. Genetic analysis of the herpes simplex virus type 1 UL9 gene: Isolation of a lacZ insertion mutant and expression in eukaryotic cells Virology. 190: 702-715. PMID 1325702 DOI: 10.1016/0042-6822(92)90908-8  0.629
1992 Zhu L, Weller SK. The six conserved helicase motifs of the UL5 gene product, a component of the herpes simplex virus type 1 helicase-primase, are essential for its function Journal of Virology. 66: 469-479. PMID 1309257 DOI: 10.1128/Jvi.66.1.469-479.1992  0.646
1992 Zhu L, Weller SK. The UL5 gene of herpes simplex virus type 1: Isolation of a lacZ insertion mutant and association of the UL5 gene product with other members of the helicase-primase complex Journal of Virology. 66: 458-468. PMID 1309255 DOI: 10.1128/Jvi.66.1.458-468.1992  0.59
1990 Weller SK, Seghatoleslami M, Shao L, Rowse D, Carmichael EP. The herpes simplex virus type 1 alkaline nuclease is not essential for viral DNA synthesis: Isolation and characterization of a lacZ insertion mutant Journal of General Virology. 71: 2941-2952. PMID 2177086 DOI: 10.1099/0022-1317-71-12-2941  0.662
1990 Heilbronn R, Weller SK, Zur Hausen H. Herpes simplex virus type 1 mutants for the origin-binding protein induce DNA amplification in the absence of viral replication Virology. 179: 478-481. PMID 2171219 DOI: 10.1016/0042-6822(90)90319-M  0.656
1989 Jacobson JG, Leib DA, Goldstein DJ, Bogard CL, Schaffer PA, Weller SK, Coen DM. A herpes simplex virus ribonucleotide reductase deletion mutant is defective for productive acute and reactivatable latent infections of mice and for replication in mouse cells. Virology. 173: 276-83. PMID 2554573 DOI: 10.1016/0042-6822(89)90244-4  0.547
1989 Coen DM, Goldstein DJ, Weller SK. Herpes simplex virus ribonucleotide reductase mutants are hypersensitive to acyclovir Antimicrobial Agents and Chemotherapy. 33: 1395-1399. PMID 2552912 DOI: 10.1128/Aac.33.8.1395  0.528
1989 Crute JJ, Tsurumi T, Zhu LA, Weller SK, Olivo PD, Challberg MD, Mocarski ES, Lehman IR. Herpes simplex virus 1 helicase-primase: a complex of three herpes-encoded gene products. Proceedings of the National Academy of Sciences of the United States of America. 86: 2186-9. PMID 2538835 DOI: 10.1073/Pnas.86.7.2186  0.595
1989 Carmichael EP, Weller SK. Herpes simplex virus type 1 DNA synthesis requires the product of the UL8 gene: Isolation and characterization of an ICP6::lacZ insertion mutation Journal of Virology. 63: 591-599. PMID 2536095 DOI: 10.1128/Jvi.63.2.591-599.1989  0.584
1988 Zhu L, Weller SK. UL5, A protein required for HSV DNA synthesis: Genetic analysis, overexpression in Escherichia coli, and generation of polyclonal antibodies Virology. 166: 366-378. PMID 2845650 DOI: 10.1016/0042-6822(88)90507-7  0.562
1988 Goldstein DJ, Weller SK. Factor(s) present in herpes simplex virus type 1-infected cells can compensate for the loss of the large subunit of the viral ribonucleotide reductase: characterization of an ICP6 deletion mutant Virology. 166: 41-51. PMID 2842955 DOI: 10.1016/0042-6822(88)90144-4  0.623
1988 Goldstein DJ, Weller SK. An ICP6::lacZ insertional mutagen is used to demonstrate that the UL52 gene of herpes simplex virus type 1 is required for virus growth and DNA synthesis Journal of Virology. 62: 2970-2977. PMID 2839713 DOI: 10.1128/Jvi.62.8.2970-2977.1988  0.589
1988 Carmichael EP, Kosovsky MJ, Weller SK. Isolation and characterization of herpes simplex virus type 1 host range mutants defective in viral DNA synthesis Journal of Virology. 62: 91-99. PMID 2824860 DOI: 10.1128/Jvi.62.1.91-99.1988  0.582
1988 Goldstein DJ, Weller SK. Herpes simplex virus type 1-induced ribonucleotide reductase activity is dispensable for virus growth and DNA synthesis: Isolation and characterization of an ICP6 lacZ insertion mutant Journal of Virology. 62: 196-205. PMID 2824847 DOI: 10.1128/Jvi.62.1.196-205.1988  0.615
1987 Weller SK, Carmichael EP, Aschman DP, Goldstein DI, Schaffer PA. Genetic and phenotypic characterization of mutants in four essential genes that map to the left half of HSV-1 UL DNA Virology. 161: 198-210. PMID 2823462 DOI: 10.1016/0042-6822(87)90186-3  0.6
1985 Gibbs JS, Chiou HC, Hall JD, Mount DW, Retondo MJ, Weller SK, Coen DM. Sequence and mapping analyses of the herpes simplex virus DNA polymerase gene predict a C-terminal substrate binding domain. Proceedings of the National Academy of Sciences of the United States of America. 82: 7969-73. PMID 2999787 DOI: 10.1073/Pnas.82.23.7969  0.541
1985 Chiou HC, Weller SK, Coen DM. Mutations in the herpes simplex virus major DNA-binding protein gene leading to altered sensitivity to DNA polymerase inhibitors Virology. 145: 213-226. PMID 2992151 DOI: 10.1016/0042-6822(85)90155-2  0.558
1985 Weller SK, Spadaro A, Schaffer JE, Murray AW, Maxam AM. Cloning, sequencing, and functional analysis of ori(L), a herpes simplex virus type 1 origin of DNA synthesis Molecular and Cellular Biology. 5: 930-942. PMID 2987682 DOI: 10.1128/Mcb.5.5.930  0.449
1984 Schaffer PA, Weller SK, Pancake BA, Coen DM. Genetics of herpes simplex virus Journal of Investigative Dermatology. 83. PMID 6330220 DOI: 10.1038/Jid.1984.18  0.578
1984 Coen DM, Aschman DP, Gelep PT, Retondo MJ, Weller SK, Schaffer PA. Fine mapping and molecular cloning of mutations in the herpes simplex virus DNA polymerase locus Journal of Virology. 49: 236-247. PMID 6317891 DOI: 10.1128/Jvi.49.1.236-247.1984  0.466
1983 Weller SK, Aschman DP, Sacks WR, Coen DM, Schaffer PA. Genetic analysis of temperature-sensitive mutants of HSV-1: The combined use of complementation and physical mapping for cistron assignment Virology. 130: 290-305. PMID 6316633 DOI: 10.1016/0042-6822(83)90084-3  0.37
1983 Weller SK, Lee KJ, Sabourin DJ, Schaffer PA. Genetic analysis of temperature-sensitive mutants which define the gene for the major herpes simplex virus type 1 DNA-binding protein Journal of Virology. 45: 354-366. PMID 6296442 DOI: 10.1128/Jvi.45.1.354-366.1983  0.592
1981 Weller SK, Temin HM. Cell killing by avian leukosis viruses Journal of Virology. 39: 713-721. PMID 6270346 DOI: 10.1128/Jvi.39.3.713-721.1981  0.578
1980 Weller SK, Joy AE, Temin HM. Correlation between cell killing and massive second round superinfection by members of some subgroups of avian leukosis virus Journal of Virology. 33: 494-506. PMID 6245246 DOI: 10.1128/Jvi.33.1.494-506.1980  0.585
1979 Temin HM, Keshet E, Weller SK. Correlation of transient accumulation of linear unintegrated viral DNA and transient cell killing by avian leukosis and reticuloendotheliosis viruses Symposia On Quantitative Biology. 44: 773-778. PMID 6253212 DOI: 10.1101/Sqb.1980.044.01.083  0.553
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