James E. Casanova - Publications

Affiliations: 
University of Virginia, Charlottesville, VA 
Area:
Cell Biology, Microbiology Biology

76 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Zhang YW, Torsilieri HM, Casanova JE. Quantitation of RhoA activation: differential binding to downstream effectors. Small Gtpases. 13: 296-306. PMID 35950594 DOI: 10.1080/21541248.2022.2111945  0.427
2021 Turn RE, Hu Y, Dewees SI, Devi N, East MP, Hardin KR, Khatib T, Linnert J, Wolfrum U, Lim MJ, Casanova JE, Caspary T, Kahn RA. The ARF GAPs ELMOD1 and ELMOD3 act at the Golgi and Cilia to Regulate Ciliogenesis and Ciliary Protein Traffic. Molecular Biology of the Cell. mbcE21090443. PMID 34818063 DOI: 10.1091/mbc.E21-09-0443  0.405
2020 D'Souza RS, Lim JY, Turgut A, Servage K, Zhang J, Orth K, Sosale N, Lazzara M, Allegood J, Casanova JE. Calcium-stimulated disassembly of focal adhesions mediated by an ORP3/IQSec1 complex. Elife. 9. PMID 32234213 DOI: 10.7554/Elife.54113  0.381
2019 Sztul E, Chen PW, Casanova JE, Cherfils J, Dacks JB, Lambright DG, Lee FS, Randazzo PA, Santy LC, Schürmann A, Wilhelmi I, Yohe ME, Kahn RA. ARF GTPases and their GEFs and GAPs: concepts and challenges. Molecular Biology of the Cell. 30: 1249-1271. PMID 31084567 DOI: 10.1091/Mbc.E18-12-0820  0.444
2019 Thomas KS, Owen KA, Conger K, Llewellyn RA, Bouton AH, Casanova JE. Non-redundant functions of FAK and Pyk2 in intestinal epithelial repair. Scientific Reports. 9: 4497. PMID 30872746 DOI: 10.1038/S41598-019-41116-1  0.369
2017 Casanova JE, Winckler B. A new Rab7 effector controls phosphoinositide conversion in endosome maturation. The Journal of Cell Biology. PMID 28928133 DOI: 10.1083/Jcb.201709034  0.387
2017 Casanova JE. Bacterial Autophagy: Offense and Defense at the Host-Pathogen Interface. Cellular and Molecular Gastroenterology and Hepatology. 4: 237-243. PMID 28660242 DOI: 10.1016/J.Jcmgh.2017.05.002  0.342
2016 D'Souza RS, Casanova JE. The BRAG/IQSec Family of Arf GEFs. Small Gtpases. 0. PMID 27739918 DOI: 10.1080/21541248.2016.1219442  0.421
2016 Billings EA, Lee CS, Owen KA, D'Souza RS, Ravichandran KS, Casanova JE. The adhesion GPCR BAI1 mediates macrophage ROS production and microbicidal activity against Gram-negative bacteria. Science Signaling. 9: ra14. PMID 26838550 DOI: 10.1126/Scisignal.Aac6250  0.451
2016 Casanova JE, Van Hook AM. Science Signaling podcast for 2 February 2016: Engulf and kill Science Signaling. 9. DOI: 10.1126/Scisignal.Aaf2668  0.383
2015 Owen KA, Anderson CJ, Casanova JE. Salmonella Suppresses the TRIF-Dependent Type I Interferon Response in Macrophages. Mbio. 7. PMID 26884434 DOI: 10.1128/Mbio.02051-15  0.376
2015 Das S, Sarkar A, Choudhury SS, Owen KA, Castillo V, Fox S, Eckmann L, Elliott MR, Casanova JE, Ernst PB. ELMO1 has an essential role in the internalization of Salmonella Typhimurium into enteric macrophages that impacts disease outcome. Cellular and Molecular Gastroenterology and Hepatology. 1: 311-324. PMID 26878033 DOI: 10.1016/J.Jcmgh.2015.02.003  0.398
2015 Owen KA, Casanova JE. Salmonella Manipulates Autophagy to "Serve and Protect". Cell Host & Microbe. 18: 517-9. PMID 26567504 DOI: 10.1016/J.Chom.2015.10.020  0.34
2015 Simmons JA, D'Souza RS, Ruas M, Galione A, Casanova JE, White JM. THE EBOLAVIRUS GLYCOPROTEIN DIRECTS FUSION THROUGH NPC1+ ENDOLYSOSOMES. Journal of Virology. PMID 26468524 DOI: 10.1128/Jvi.01828-15  0.326
2015 Mingo RM, Simmons JA, Shoemaker CJ, Nelson EA, Schornberg KL, D'Souza RS, Casanova JE, White JM. Ebola virus and severe acute respiratory syndrome coronavirus display late cell entry kinetics: evidence that transport to NPC1+ endolysosomes is a rate-defining step. Journal of Virology. 89: 2931-43. PMID 25552710 DOI: 10.1128/Jvi.03398-14  0.329
2015 Hallstrom KN, Srikanth CV, Agbor TA, Dumont CM, Peters KN, Paraoan L, Casanova JE, Boll EJ, McCormick BA. PERP, a host tetraspanning membrane protein, is required for Salmonella-induced inflammation. Cellular Microbiology. 17: 843-59. PMID 25486861 DOI: 10.1111/Cmi.12406  0.502
2014 Owen KA, Meyer CB, Bouton AH, Casanova JE. Activation of focal adhesion kinase by Salmonella suppresses autophagy via an Akt/mTOR signaling pathway and promotes bacterial survival in macrophages. Plos Pathogens. 10: e1004159. PMID 24901456 DOI: 10.1371/Journal.Ppat.1004159  0.458
2014 D'Souza RS, Semus R, Billings EA, Meyer CB, Conger K, Casanova JE. Rab4 orchestrates a small GTPase cascade for recruitment of adaptor proteins to early endosomes. Current Biology : Cb. 24: 1187-98. PMID 24835460 DOI: 10.1016/J.Cub.2014.04.003  0.452
2013 Casanova JE, Hsu VW, Jackson CL, Kahn RA, Roy CR, Stow JL, Wandinger-Ness A, Sztul E. Meeting report - Arf and Rab family G proteins. Journal of Cell Science. 126: 5313-6. PMID 24293329 DOI: 10.1242/Jcs.143610  0.329
2012 Casanova JE. Advantages and limitations of cell-based assays for GTPase activation and regulation. Cellular Logistics. 2: 147-150. PMID 23181197 DOI: 10.4161/cl.22045  0.354
2012 Myers KR, Wang G, Sheng Y, Conger KK, Casanova JE, Zhu JJ. Arf6-GEF BRAG1 regulates JNK-mediated synaptic removal of GluA1-containing AMPA receptors: a new mechanism for nonsyndromic X-linked mental disorder. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 11716-26. PMID 22915114 DOI: 10.1523/Jneurosci.1942-12.2012  0.358
2012 Moravec R, Conger KK, D'Souza R, Allison AB, Casanova JE. BRAG2/GEP100/IQSec1 interacts with clathrin and regulates α5β1 integrin endocytosis through activation of ADP ribosylation factor 5 (Arf5). The Journal of Biological Chemistry. 287: 31138-47. PMID 22815487 DOI: 10.1074/Jbc.M112.383117  0.701
2011 Owen KA, Abshire MY, Tilghman RW, Casanova JE, Bouton AH. FAK regulates intestinal epithelial cell survival and proliferation during mucosal wound healing. Plos One. 6: e23123. PMID 21887232 DOI: 10.1371/Journal.Pone.0023123  0.36
2011 Das S, Owen KA, Ly KT, Park D, Black SG, Wilson JM, Sifri CD, Ravichandran KS, Ernst PB, Casanova JE. Brain angiogenesis inhibitor 1 (BAI1) is a pattern recognition receptor that mediates macrophage binding and engulfment of Gram-negative bacteria. Proceedings of the National Academy of Sciences of the United States of America. 108: 2136-41. PMID 21245295 DOI: 10.1073/Pnas.1014775108  0.734
2010 Nichols CD, Casanova JE. Salmonella-directed recruitment of new membrane to invasion foci via the host exocyst complex. Current Biology : Cb. 20: 1316-20. PMID 20579884 DOI: 10.1016/J.Cub.2010.05.065  0.43
2010 Das S, Ly K, Park D, Black SG, Wilson JM, Ravichandran KS, Ernst PB, Casanova JE. 1017 Recognition of Enteric Bacteria by a New Pattern Recognition Receptor Bai1 (Brain Angiogenesis Inhibitor 1) Gastroenterology. 138: S-147. DOI: 10.1016/S0016-5085(10)60676-2  0.661
2009 Ly KT, Casanova JE. Abelson tyrosine kinase facilitates Salmonella enterica serovar Typhimurium entry into epithelial cells. Infection and Immunity. 77: 60-9. PMID 18936177 DOI: 10.1128/Iai.00639-08  0.735
2008 Kitt KN, Hernández-Deviez D, Ballantyne SD, Spiliotis ET, Casanova JE, Wilson JM. Rab14 regulates apical targeting in polarized epithelial cells. Traffic (Copenhagen, Denmark). 9: 1218-31. PMID 18429929 DOI: 10.1111/J.1600-0854.2008.00752.X  0.452
2008 Myers KR, Casanova JE. Regulation of actin cytoskeleton dynamics by Arf-family GTPases. Trends in Cell Biology. 18: 184-92. PMID 18328709 DOI: 10.1016/J.Tcb.2008.02.002  0.435
2008 Hall B, McLean MA, Davis K, Casanova JE, Sligar SG, Schwartz MA. A fluorescence resonance energy transfer activation sensor for Arf6. Analytical Biochemistry. 374: 243-9. PMID 18162163 DOI: 10.1016/J.Ab.2007.11.032  0.445
2008 Cuthbert EJ, Davis KK, Casanova JE. Substrate specificities and activities of AZAP family Arf GAPs in vivo. American Journal of Physiology. Cell Physiology. 294: C263-70. PMID 18003747 DOI: 10.1152/Ajpcell.00292.2007  0.688
2008 Hall B, McLean MA, Davis K, Casanova JE, Sligar SG, Schwartz MA. A FRET Activation Sensor for Arf6 Analytical Biochemistry. 374: 243. DOI: 10.1016/J.Ab.2007.11.03  0.484
2007 Balasubramanian N, Scott DW, Castle JD, Casanova JE, Schwartz MA. Arf6 and microtubules in adhesion-dependent trafficking of lipid rafts. Nature Cell Biology. 9: 1381-91. PMID 18026091 DOI: 10.1038/Ncb1657  0.414
2007 Casanova JE. Regulation of Arf activation: the Sec7 family of guanine nucleotide exchange factors. Traffic (Copenhagen, Denmark). 8: 1476-85. PMID 17850229 DOI: 10.1111/J.1600-0854.2007.00634.X  0.483
2007 Ly KT, Casanova JE. Mechanisms of Salmonella entry into host cells. Cellular Microbiology. 9: 2103-11. PMID 17593246 DOI: 10.1111/J.1462-5822.2007.00992.X  0.722
2007 Dunphy JL, Ye K, Casanova JE. Nuclear functions of the Arf guanine nucleotide exchange factor BRAG2. Traffic (Copenhagen, Denmark). 8: 661-72. PMID 17461797 DOI: 10.1111/J.1600-0854.2007.00561.X  0.377
2007 Ma Z, Nie Z, Luo R, Casanova JE, Ravichandran KS. Regulation of Arf6 and ACAP1 signaling by the PTB-domain-containing adaptor protein GULP. Current Biology : Cb. 17: 722-7. PMID 17398097 DOI: 10.1016/J.Cub.2007.03.014  0.53
2007 Smith AC, Won DH, Braun V, Jiang X, Macrae C, Casanova JE, Scidmore MA, Grinstein S, Meyer T, Brumell JH. A network of Rab GTPases controls phagosome maturation and is modulated by Salmonella enterica serovar Typhimurium Journal of Cell Biology. 176: 263-268. PMID 17261845 DOI: 10.1083/Jcb.200611056  0.342
2006 Yoon HY, Miura K, Cuthbert EJ, Davis KK, Ahvazi B, Casanova JE, Randazzo PA. ARAP2 effects on the actin cytoskeleton are dependent on Arf6-specific GTPase-activating-protein activity and binding to RhoA-GTP. Journal of Cell Science. 119: 4650-66. PMID 17077126 DOI: 10.1242/Jcs.03237  0.689
2006 Shi J, Casanova JE. Invasion of host cells by Salmonella typhimurium requires focal adhesion kinase and p130Cas. Molecular Biology of the Cell. 17: 4698-708. PMID 16914515 DOI: 10.1091/Mbc.E06-06-0492  0.468
2006 Casanova JE. There goes the neighborhood. Focus on "localized PtdIns 3,5-P2 synthesis to regulate early endosome dynamics and fusion". American Journal of Physiology. Cell Physiology. 291: C231-3. PMID 16825602 DOI: 10.1152/Ajpcell.00128.2006  0.356
2006 Shmuel M, Santy LC, Frank S, Avrahami D, Casanova JE, Altschuler Y. ARNO through its coiled-coil domain regulates endocytosis at the apical surface of polarized epithelial cells. The Journal of Biological Chemistry. 281: 13300-8. PMID 16484220 DOI: 10.1074/Jbc.M513723200  0.436
2006 Dunphy JL, Moravec R, Ly K, Lasell TK, Melancon P, Casanova JE. The Arf6 GEF GEP100/BRAG2 regulates cell adhesion by controlling endocytosis of beta1 integrins. Current Biology : Cb. 16: 315-20. PMID 16461286 DOI: 10.1016/J.Cub.2005.12.032  0.76
2006 Hurtado-Lorenzo A, Skinner M, El Annan J, Futai M, Sun-Wada GH, Bourgoin S, Casanova J, Wildeman A, Bechoua S, Ausiello DA, Brown D, Marshansky V. V-ATPase interacts with ARNO and Arf6 in early endosomes and regulates the protein degradative pathway. Nature Cell Biology. 8: 124-36. PMID 16415858 DOI: 10.1038/Ncb1348  0.389
2005 Santy LC, Ravichandran KS, Casanova JE. The DOCK180/Elmo complex couples ARNO-mediated Arf6 activation to the downstream activation of Rac1. Current Biology : Cb. 15: 1749-54. PMID 16213822 DOI: 10.1016/J.Cub.2005.08.052  0.535
2005 Liu L, Liao H, Castle A, Zhang J, Casanova J, Szabo G, Castle D. SCAMP2 interacts with Arf6 and phospholipase D1 and links their function to exocytotic fusion pore formation in PC12 cells. Molecular Biology of the Cell. 16: 4463-72. PMID 16030257 DOI: 10.1091/Mbc.E05-03-0231  0.455
2005 Shi J, Scita G, Casanova JE. WAVE2 signaling mediates invasion of polarized epithelial cells by Salmonella typhimurium. The Journal of Biological Chemistry. 280: 29849-55. PMID 15929989 DOI: 10.1074/Jbc.M500617200  0.373
2005 Smith AC, Cirulis JT, Casanova JE, Scidmore MA, Brumell JH. Interaction of the Salmonella-containing vacuole with the endocytic recycling system. The Journal of Biological Chemistry. 280: 24634-41. PMID 15886200 DOI: 10.1074/Jbc.M500358200  0.427
2004 Martinu L, Masuda-Robens JM, Robertson SE, Santy LC, Casanova JE, Chou MM. The TBC (Tre-2/Bub2/Cdc16) domain protein TRE17 regulates plasma membrane-endosomal trafficking through activation of Arf6. Molecular and Cellular Biology. 24: 9752-62. PMID 15509780 DOI: 10.1128/Mcb.24.22.9752-9762.2004  0.485
2004 Lyons S, Wang L, Casanova JE, Sitaraman SV, Merlin D, Gewirtz AT. Salmonella typhimurium transcytoses flagellin via an SPI2-mediated vesicular transport pathway. Journal of Cell Science. 117: 5771-80. PMID 15507487 DOI: 10.1242/Jcs.01500  0.437
2004 Hernández-Deviez DJ, Roth MG, Casanova JE, Wilson JM. ARNO and ARF6 regulate axonal elongation and branching through downstream activation of phosphatidylinositol 4-phosphate 5-kinase alpha. Molecular Biology of the Cell. 15: 111-20. PMID 14565977 DOI: 10.1091/Mbc.E03-06-0410  0.373
2003 Li HS, Shome K, Rojas R, Rizzo MA, Vasudevan C, Fluharty E, Santy LC, Casanova JE, Romero G. The guanine nucleotide exchange factor ARNO mediates the activation of ARF and phospholipase D by insulin. Bmc Cell Biology. 4: 13. PMID 12969509 DOI: 10.1186/1471-2121-4-13  0.378
2003 Criss AK, Casanova JE. Coordinate regulation of Salmonella enterica serovar Typhimurium invasion of epithelial cells by the Arp2/3 complex and Rho GTPases. Infection and Immunity. 71: 2885-91. PMID 12704163 DOI: 10.1128/Iai.71.5.2885-2891.2003  0.449
2002 Casanova JE. Epithelial cell cytoskeleton and intracellular trafficking V. Confluence of membrane trafficking and motility in epithelial cell models. American Journal of Physiology. Gastrointestinal and Liver Physiology. 283: G1015-9. PMID 12381513 DOI: 10.1152/Ajpgi.00255.2002  0.39
2002 Hunzicker-Dunn M, Gurevich VV, Casanova JE, Mukherjee S. ARF6: a newly appreciated player in G protein-coupled receptor desensitization. Febs Letters. 521: 3-8. PMID 12067715 DOI: 10.1016/S0014-5793(02)02822-3  0.355
2002 Hernández-Deviez DJ, Casanova JE, Wilson JM. Regulation of dendritic development by the ARF exchange factor ARNO. Nature Neuroscience. 5: 623-4. PMID 12032543 DOI: 10.1038/Nn865  0.372
2002 Santy LC, Casanova JE. GTPase signaling: bridging the GAP between ARF and Rho. Current Biology : Cb. 12: R360-2. PMID 12015138 DOI: 10.1016/S0960-9822(02)00860-6  0.45
2001 Criss AK, Silva M, Casanova JE, McCormick BA. Regulation of Salmonella-induced Neutrophil Transmigration by Epithelial ADP-ribosylation Factor 6 Journal of Biological Chemistry. 276: 48431-48439. PMID 11641400 DOI: 10.1074/Jbc.M106969200  0.434
2001 Santy LC, Casanova JE. Activation of ARF6 by ARNO stimulates epithelial cell migration through downstream activation of both Rac1 and phospholipase D Journal of Cell Biology. 154: 599-610. PMID 11481345 DOI: 10.1083/Jcb.200104019  0.487
2001 Salvador LM, Mukherjee S, Kahn RA, Lamm MLG, Fazleabas AT, Maizels ET, Bader MF, Hamm H, Rasenick MM, Casanova JE, Hunzieker-Dunn M. Activation of the Luteinizing Hormone/Choriogonadotropin Hormone Receptor Promotes ADP Ribosylation Factor 6 Activation in Porcine Ovarian Follicular Membranes Journal of Biological Chemistry. 276: 33773-33781. PMID 11448949 DOI: 10.1074/Jbc.M101498200  0.401
2001 Baldeón ME, Ceresa BP, Casanova JE. Expression of constitutively active rab5 uncouples maturation of the Salmonella-containing vacuole from intracellular replication Cellular Microbiology. 3: 473-486. PMID 11437833 DOI: 10.1046/J.1462-5822.2001.00130.X  0.356
2001 Criss AK, Ahlgren DM, Jou TS, McCormick BA, Casanova JE. The GTPase Rac1 selectively regulates Salmonella invasion at the apical plasma membrane of polarized epithelial cells Journal of Cell Science. 114: 1331-1341. PMID 11256999  0.43
2001 Santy LC, Frank SR, Casanova JE. Expression and analysis of ARNO and ARNO mutants and their effects on adp-ribosylation factor (ARF)-mediated actin cytoskeletal rearrangements Methods in Enzymology. 329: 256-264. PMID 11210542 DOI: 10.1016/S0076-6879(01)29086-7  0.458
2001 Goldenring JR, Aron LM, Lapierre LA, Navarre J, Casanova JE. Expression and properties of Rab25 in polarized madin-darby canine kidney cells Methods in Enzymology. 329: 225-234. PMID 11210538 DOI: 10.1016/S0076-6879(01)29082-X  0.327
2001 Mukherjee S, Casanova JE, Hunzicker-Dunn M. Desensitization of the Luteinizing Hormone/Choriogonadotropin Receptor in Ovarian Follicular Membranes Is Inhibited by Catalytically Inactive ARNO + Journal of Biological Chemistry. 276: 6524-6528. PMID 11139567 DOI: 10.1074/Jbc.C000725200  0.309
2000 Wang X, Kumar R, Navarre J, Casanova JE, Goldenring JR. Regulation of vesicle trafficking in Madin-Darby canine kidney cells by Rab11a and Rab25 Journal of Biological Chemistry. 275: 29138-29146. PMID 10869360 DOI: 10.1074/Jbc.M004410200  0.385
2000 Mukherjee S, Gurevich VV, Jones JCR, Casanova JE, Frank SR, Maizels ET, Bader MF, Kahn RA, Palczewski K, Aktories K, Hunzicker-Dunn M. The ADP ribosylation factor nucleotide exchange factor ARNO promotes β- arrestin release necessary for luteinizing hormone/choriogonadotropin receptor desensitization Proceedings of the National Academy of Sciences of the United States of America. 97: 5901-5906. PMID 10811902 DOI: 10.1073/Pnas.100127097  0.388
2000 Caumont AS, Vitale N, Gensse M, Galas MC, Casanova JE, Bader MF. Identification of a plasma membrane-associated guanine nucleotide exchange factor for ARF6 in chromaffin cells. Possible role in the regulated exocytotic pathway Journal of Biological Chemistry. 275: 15637-15644. PMID 10748097 DOI: 10.1074/jbc.M908347199  0.36
2000 Jackson CL, Casanova JE. Turning on ARF: The Sec7 family of guanine-nucleotide-exchange factors Trends in Cell Biology. 10: 60-67. PMID 10652516 DOI: 10.1016/S0962-8924(99)01699-2  0.453
1999 Santy LC, Frank SR, Hatfield JC, Casanova JE. Regulation of ARNO nucleotide exchange by a PH domain electrostatic switch Current Biology. 9: 1173-1176. PMID 10531036 DOI: 10.1016/S0960-9822(00)80019-6  0.392
1999 Casanova JE, Wang X, Kumar R, Bhartur SG, Navarre J, Woodrum JE, Altschuler Y, Ray GS, Goldenring JR. Association of Rab25 and Rab11a with the apical recycling system of polarized Madin-Darby Canine Kidney cells Molecular Biology of the Cell. 10: 47-61. PMID 9880326 DOI: 10.1091/Mbc.10.1.47  0.303
1998 Frank SR, Hatfield JC, Casanova JE. Remodeling of the actin cytoskeleton is coordinately regulated by protein kinase C and the ADP-ribosylation factor nucleotide exchange factor ARNO Molecular Biology of the Cell. 9: 3133-3146. PMID 9802902  0.42
1998 Frank S, Upender S, Hansen SH, Casanova JE. ARNO is a guanine nucleotide exchange factor for ADP-ribosylation factor 6 Journal of Biological Chemistry. 273: 23-27. PMID 9417041 DOI: 10.1074/jbc.273.1.23  0.359
1995 Li S, Okamoto T, Chun M, Sargiacomo M, Casanova JE, Hansen SH, Nishimoto I, Lisanti MP. .. Evidence for a regulated interaction between heterotrimeric G proteins and caveolin. J Biol Chem.. 15693-701. PMID 7797570 DOI: 10.1074/Jbc.270.26.15693  0.417
1995 Hansen SH, Olsson A, Casanova JE. Wortmannin, an inhibitor of phosphoinositide 3-kinase, inhibits transcytosis in polarized epithelial cells Journal of Biological Chemistry. 270: 28425-28432. PMID 7499348 DOI: 10.1074/jbc.270.47.28425  0.378
1994 Hansen SH, Casanova JE. Gsα stimulates transcytosis and apical secretion in MDCK cells through cAMP and protein kinase A Journal of Cell Biology. 126: 677-687. PMID 8045932 DOI: 10.1083/jcb.126.3.677  0.355
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