| Year |
Citation |
Score |
| 2023 |
Michaels YS, Durland LJ, Zandstra PW. Engineering T Cell Development for the Next Generation of Stem Cell-Derived Immunotherapies. Gen Biotechnology. 2: 106-119. PMID 37928777 DOI: 10.1089/genbio.2023.0008 |
0.409 |
|
| 2023 |
Li B, Rodrigo-Torres D, Pelz C, Innes B, Canaday P, Chai S, Zandstra P, Bader GD, Grompe M. Cell networks in the mouse liver during partial hepatectomy. Biorxiv : the Preprint Server For Biology. PMID 37503083 DOI: 10.1101/2023.07.16.549116 |
0.391 |
|
| 2022 |
Elbaz J, Puri MC, Faiz M, Bang KWA, Nguyen L, Makovoz B, Gertsenstein M, Hussein SMI, Zandstra PW, Briollais L, Shakiba N, Nagy A. Highly efficient reprogrammable mouse lines with integrated reporters to track the route to pluripotency. Proceedings of the National Academy of Sciences of the United States of America. 119: e2207824119. PMID 36454756 DOI: 10.1073/pnas.2207824119 |
0.779 |
|
| 2022 |
Prochazka L, Michaels YS, Lau C, Jones RD, Siu M, Yin T, Wu D, Jang E, Vázquez-Cantú M, Gilbert PM, Kaul H, Benenson Y, Zandstra PW. Synthetic gene circuits for cell state detection and protein tuning in human pluripotent stem cells. Molecular Systems Biology. 18: e10886. PMID 36366891 DOI: 10.15252/msb.202110886 |
0.368 |
|
| 2022 |
Kaul H, Werschler N, Jones RD, Siu MM, Tewary M, Hagner A, Ostblom J, Aguilar-Hidalgo D, Zandstra PW. Virtual cells in a virtual microenvironment recapitulate early development-like patterns in human pluripotent stem cell colonies. Stem Cell Reports. PMID 36332630 DOI: 10.1016/j.stemcr.2022.10.004 |
0.389 |
|
| 2022 |
Michaels YS, Edgar JM, Major MC, Castle EL, Zimmerman C, Yin T, Hagner A, Lau C, Hsu HH, Ibañez-Rios MI, Durland LJ, Knapp DJHF, Zandstra PW. DLL4 and VCAM1 enhance the emergence of T cell-competent hematopoietic progenitors from human pluripotent stem cells. Science Advances. 8: eabn5522. PMID 36001668 DOI: 10.1126/sciadv.abn5522 |
0.494 |
|
| 2022 |
Edgar JM, Michaels YS, Zandstra PW. Multi-objective optimization reveals time- and dose-dependent inflammatory cytokine-mediated regulation of human stem cell derived T-cell development. Npj Regenerative Medicine. 7: 11. PMID 35087040 DOI: 10.1038/s41536-022-00210-1 |
0.47 |
|
| 2021 |
Ma J, Tran G, Wan AMD, Young EWK, Kumacheva E, Iscove NN, Zandstra PW. Microdroplet-based one-step RT-PCR for ultrahigh throughput single-cell multiplex gene expression analysis and rare cell detection. Scientific Reports. 11: 6777. PMID 33762663 DOI: 10.1038/s41598-021-86087-4 |
0.376 |
|
| 2021 |
Dziedzicka D, Tewary M, Keller A, Tilleman L, Prochazka L, Östblom J, Couvreu De Deckersberg E, Markouli C, Franck S, Van Nieuwerburgh F, Spits C, Zandstra PW, Sermon K, Geens M. Endogenous suppression of WNT signalling in human embryonic stem cells leads to low differentiation propensity towards definitive endoderm. Scientific Reports. 11: 6137. PMID 33731744 DOI: 10.1038/s41598-021-85447-4 |
0.457 |
|
| 2020 |
Thavandiran N, Hale C, Blit P, Sandberg ML, McElvain ME, Gagliardi M, Sun B, Witty A, Graham G, Do VTH, Bakooshli MA, Le H, Ostblom J, McEwen S, Chau E, ... ... Zandstra PW, et al. Functional arrays of human pluripotent stem cell-derived cardiac microtissues. Scientific Reports. 10: 6919. PMID 32332814 DOI: 10.1038/S41598-020-62955-3 |
0.397 |
|
| 2019 |
Tewary M, Dziedzicka D, Ostblom J, Prochazka L, Shakiba N, Heydari T, Aguilar-Hidalgo D, Woodford C, Piccinini E, Becerra-Alonso D, Vickers A, Louis B, Rahman N, Danovi D, Geens M, ... ... Zandstra PW, et al. High-throughput micropatterning platform reveals Nodal-dependent bisection of peri-gastrulation-associated versus preneurulation-associated fate patterning. Plos Biology. 17: e3000081. PMID 31634368 DOI: 10.1371/Journal.Pbio.3000081 |
0.775 |
|
| 2019 |
Zhang S, Scott EY, Singh J, Chen Y, Zhang Y, Elsayed M, Chamberlain MD, Shakiba N, Adams K, Yu S, Morshead CM, Zandstra PW, Wheeler AR. The optoelectronic microrobot: A versatile toolbox for micromanipulation. Proceedings of the National Academy of Sciences of the United States of America. PMID 31289234 DOI: 10.1073/Pnas.1903406116 |
0.743 |
|
| 2019 |
Romagnuolo R, Masoudpour H, Porta-Sánchez A, Qiang B, Barry J, Laskary A, Qi X, Massé S, Magtibay K, Kawajiri H, Wu J, Valdman Sadikov T, Rothberg J, Panchalingam KM, Titus E, ... ... Zandstra PW, et al. Human Embryonic Stem Cell-Derived Cardiomyocytes Regenerate the Infarcted Pig Heart but Induce Ventricular Tachyarrhythmias. Stem Cell Reports. PMID 31056479 DOI: 10.1016/J.Stemcr.2019.04.005 |
0.387 |
|
| 2019 |
Shakiba N, Fahmy A, Jayakumaran G, McGibbon S, David L, Trcka D, Elbaz J, Puri MC, Nagy A, van der Kooy D, Goyal S, Wrana JL, Zandstra PW. Cell competition during reprogramming gives rise to dominant clones. Science (New York, N.Y.). PMID 30898844 DOI: 10.1126/Science.Aan0925 |
0.824 |
|
| 2019 |
Vigilante A, Laddach A, Moens N, Meleckyte R, Leha A, Ghahramani A, Culley OJ, Kathuria A, Hurling C, Vickers A, Wiseman E, Tewary M, Zandstra PW, Durbin R, et al. Identifying Extrinsic versus Intrinsic Drivers of Variation in Cell Behavior in Human iPSC Lines from Healthy Donors. Cell Reports. 26: 2078-2087.e3. PMID 30784590 DOI: 10.1016/J.Celrep.2019.01.094 |
0.362 |
|
| 2019 |
Ostblom J, Nazareth EJP, Tewary M, Zandstra PW. Context-explorer: Analysis of spatially organized protein expression in high-throughput screens. Plos Computational Biology. 15: e1006384. PMID 30601802 DOI: 10.1371/journal.pcbi.1006384 |
0.378 |
|
| 2018 |
Zhang S, Shakiba N, Chen Y, Zhang Y, Tian P, Singh J, Chamberlain MD, Satkauskas M, Flood AG, Kherani NP, Yu S, Zandstra PW, Wheeler AR. Patterned Optoelectronic Tweezers: A New Scheme for Selecting, Moving, and Storing Dielectric Particles and Cells. Small (Weinheim An Der Bergstrasse, Germany). e1803342. PMID 30307718 DOI: 10.1002/Smll.201803342 |
0.707 |
|
| 2018 |
Tewary M, Shakiba N, Zandstra PW. Stem cell bioengineering: building from stem cell biology. Nature Reviews. Genetics. PMID 30089805 DOI: 10.1038/S41576-018-0040-Z |
0.827 |
|
| 2018 |
Tewary M, Zandstra PW. Mechanics-guided developmental fate patterning. Nature Materials. 17: 571-572. PMID 29941948 DOI: 10.1038/S41563-018-0121-6 |
0.546 |
|
| 2018 |
Lipsitz YY, Woodford C, Yin T, Hanna JH, Zandstra PW. Modulating cell state to enhance suspension expansion of human pluripotent stem cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 29866848 DOI: 10.1073/Pnas.1714099115 |
0.639 |
|
| 2018 |
Bahr C, von Paleske L, Uslu VV, Remeseiro S, Takayama N, Ng SW, Murison A, Langenfeld K, Petretich M, Scognamiglio R, Zeisberger P, Benk AS, Amit I, Zandstra PW, Lupien M, et al. Author Correction: A Myc enhancer cluster regulates normal and leukaemic haematopoietic stem cell hierarchies. Nature. PMID 29769714 DOI: 10.1038/S41586-018-0113-3 |
0.404 |
|
| 2018 |
Lipsitz YY, Tonge P, Zandstra PW. Chemically controlled aggregation of pluripotent stem cells. Biotechnology and Bioengineering. PMID 29679475 DOI: 10.1002/Bit.26719 |
0.472 |
|
| 2018 |
Tedesco S, De Majo F, Kim J, Trenti A, Trevisi L, Fadini GP, Bolego C, Zandstra PW, Cignarella A, Vitiello L. Convenience versus Biological Significance: Are PMA-Differentiated THP-1 Cells a Reliable Substitute for Blood-Derived Macrophages When StudyingPolarization? Frontiers in Pharmacology. 9: 71. PMID 29520230 DOI: 10.3389/Fphar.2018.00071 |
0.393 |
|
| 2018 |
Yachie-Kinoshita A, Onishi K, Ostblom J, Langley MA, Posfai E, Rossant J, Zandstra PW. Modeling signaling-dependent pluripotency with Boolean logic to predict cell fate transitions. Molecular Systems Biology. 14: e7952. PMID 29378814 DOI: 10.15252/Msb.20177952 |
0.696 |
|
| 2018 |
Bahr C, von Paleske L, Uslu VV, Remeseiro S, Takayama N, Ng SW, Murison A, Langenfeld K, Petretich M, Scognamiglio R, Zeisberger P, Benk AS, Amit I, Zandstra PW, Lupien M, et al. A Myc enhancer cluster regulates normal and leukaemic haematopoietic stem cell hierarchies. Nature. PMID 29342133 DOI: 10.1038/Nature25193 |
0.548 |
|
| 2018 |
Ng SW, Xie SZ, Wagenblast E, Takayama N, Jin L, Mbong N, Murison A, Erwin SE, Mitchell A, Van Galen P, Lupien M, Minden MD, Wang JC, Zandstra PW, Dick JE. Identification of Gene Regulatory Networks Governing Stemness Properties of Human HSC and LSC Blood. 132: 3832-3832. DOI: 10.1182/Blood-2018-99-114314 |
0.476 |
|
| 2018 |
Cohen S, Roy J, Lachance S, Marinier A, Delisle J, Roy D, Busque L, Ahmad I, Bambace NM, Barabe F, Bernard L, Kiss TL, Bouchard P, Caudrelier P, Larochelle F, ... ... Zandstra PW, et al. Single UM171 Expanded Cord Blood Permits Transplantation of Better HLA Matched Cords with Excellent Gvhd Relapse Free Survival Blood. 132: 4658-4658. DOI: 10.1182/Blood-2018-99-110188 |
0.396 |
|
| 2018 |
Romagnuolo R, Masoudpoor H, Porta-Sanchez A, Qiang B, Barry J, Qi X, Masse S, Magtibay K, Laskary A, Wu J, Valdman-Sadikov T, Rothberg J, Titus E, Li R, Zandstra P, et al. REGENERATING THE INFARCTED PIG HEART WITH HUMAN EMBRYONIC STEM CELL-DERIVED CARDIOMYOCYTES INDUCES VENTRICULAR TACHYARRHYTHMIAS Canadian Journal of Cardiology. 34: S140-S141. DOI: 10.1016/J.Cjca.2018.07.196 |
0.476 |
|
| 2017 |
Wang W, Fujii H, Kim HJ, Hermans K, Usenko T, Xie S, Luo ZJ, Ma J, Celso CL, Dick JE, Schroeder T, Krueger J, Wall D, Egeler RM, Zandstra PW. Enhanced human hematopoietic stem and progenitor cell engraftment by blocking donor T cell-mediated TNFα signaling. Science Translational Medicine. 9. PMID 29263228 DOI: 10.1126/Scitranslmed.Aag3214 |
0.567 |
|
| 2017 |
Yoon C, Song H, Yin T, Bausch-Fluck D, Frei AP, Kattman S, Dubois N, Witty AD, Hewel JA, Guo H, Emili A, Wollscheid B, Keller G, Zandstra PW. FZD4 Marks Lateral Plate Mesoderm and Signals with NORRIN to Increase Cardiomyocyte Induction from Pluripotent Stem Cell-Derived Cardiac Progenitors. Stem Cell Reports. PMID 29249665 DOI: 10.1016/J.Stemcr.2017.11.008 |
0.604 |
|
| 2017 |
Tewary M, Ostblom J, Prochazka L, Zulueta-Coarasa T, Shakiba N, Fernandez-Gonzalez R, Zandstra PW. A stepwise model of Reaction-Diffusion and Positional-Information governs self-organized human peri-gastrulation-like patterning. Development (Cambridge, England). PMID 28870989 DOI: 10.1242/Dev.149658 |
0.748 |
|
| 2017 |
Zhou W, Mahshid SS, Wang W, Vallée-Bélisle A, Zandstra PW, Sargent EH, Kelley SO. Steric Hindrance Assay for Secreted Factors in Stem Cell Culture. Acs Sensors. 2: 495-500. PMID 28723184 DOI: 10.1021/Acssensors.7B00136 |
0.593 |
|
| 2017 |
Shakiba N, Zandstra PW. Engineering cell fitness: lessons for regenerative medicine. Current Opinion in Biotechnology. 47: 7-15. PMID 28551499 DOI: 10.1016/J.Copbio.2017.05.005 |
0.81 |
|
| 2017 |
Rahman N, Brauer PM, Ho L, Usenko T, Tewary M, Zúñiga-Pflücker JC, Zandstra PW. Engineering the haemogenic niche mitigates endogenous inhibitory signals and controls pluripotent stem cell-derived blood emergence. Nature Communications. 8: 15380. PMID 28541275 DOI: 10.1038/Ncomms15380 |
0.556 |
|
| 2017 |
Shukla S, Langley MA, Singh J, Edgar JM, Mohtashami M, Zúñiga-Pflücker JC, Zandstra PW. Progenitor T-cell differentiation from hematopoietic stem cells using Delta-like-4 and VCAM-1. Nature Methods. PMID 28394335 DOI: 10.1038/Nmeth.4258 |
0.559 |
|
| 2017 |
Martine LC, Holzapfel BM, McGovern JA, Wagner F, Quent VM, Hesami P, Wunner FM, Vaquette C, De-Juan-Pardo EM, Brown TD, Nowlan B, Wu DJ, Hutmacher CO, Moi D, Oussenko T, ... ... Zandstra PW, et al. Engineering a humanized bone organ model in mice to study bone metastases. Nature Protocols. 12: 639-663. PMID 28253234 DOI: 10.1038/Nprot.2017.002 |
0.364 |
|
| 2017 |
Lipsitz YY, Bedford P, Davies AH, Timmins NE, Zandstra PW. Achieving Efficient Manufacturing and Quality Assurance through Synthetic Cell Therapy Design. Cell Stem Cell. 20: 13-17. PMID 28061350 DOI: 10.1016/J.Stem.2016.12.003 |
0.407 |
|
| 2017 |
Bahr C, von Palekse L, Uslu V, Remeseiro S, Takayama N, Ng S, Murison A, Langenfeld K, Petretich M, Scognamiglio R, Zeisberger P, Benk A, Amit I, Zandstra P, Lupien M, et al. A cluster of enhancer modules directs differential MYC expression along the normal and leukemic haematopoietic stem cell hierarchies Experimental Hematology. 53: S130-S131. DOI: 10.1016/J.Exphem.2017.06.329 |
0.486 |
|
| 2017 |
Prochazka L, Benenson Y, Zandstra PW. Synthetic gene circuits and cellular decision-making in human pluripotent stem cells Current Opinion in Systems Biology. 5: 93-103. DOI: 10.1016/J.Coisb.2017.09.003 |
0.544 |
|
| 2016 |
Ng SW, Mitchell A, Kennedy JA, Chen WC, McLeod J, Ibrahimova N, Arruda A, Popescu A, Gupta V, Schimmer AD, Schuh AC, Yee KW, Bullinger L, Herold T, Görlich D, ... ... Zandstra PW, et al. A 17-gene stemness score for rapid determination of risk in acute leukaemia. Nature. PMID 27926740 DOI: 10.1038/Nature20598 |
0.428 |
|
| 2016 |
Knapp DJ, Hammond CA, Aghaeepour N, Miller PH, Pellacani D, Beer PA, Sachs K, Qiao W, Wang W, Humphries RK, Sauvageau G, Zandstra PW, Bendall SC, Nolan GP, Hansen C, et al. Distinct signaling programs control human hematopoietic stem cell survival and proliferation. Blood. PMID 27827829 DOI: 10.1182/Blood-2016-09-740654 |
0.648 |
|
| 2016 |
Yuzwa SA, Yang G, Borrett MJ, Clarke G, Cancino GI, Zahr SK, Zandstra PW, Kaplan DR, Miller FD. Proneurogenic Ligands Defined by Modeling Developing Cortex Growth Factor Communication Networks. Neuron. PMID 27545711 DOI: 10.1016/J.Neuron.2016.07.037 |
0.432 |
|
| 2016 |
Müller E, Wang W, Qiao W, Bornhäuser M, Zandstra PW, Werner C, Pompe T. Distinguishing autocrine and paracrine signals in hematopoietic stem cell culture using a biofunctional microcavity platform. Scientific Reports. 6: 31951. PMID 27535453 DOI: 10.1038/Srep31951 |
0.623 |
|
| 2016 |
Nazareth EJ, Rahman N, Yin T, Zandstra PW. A Multi-Lineage Screen Reveals mTORC1 Inhibition Enhances Human Pluripotent Stem Cell Mesendoderm and Blood Progenitor Production. Stem Cell Reports. 6: 679-91. PMID 27132889 DOI: 10.1016/J.Stemcr.2016.04.003 |
0.542 |
|
| 2016 |
Lechman ER, Gentner B, Ng SW, Schoof EM, van Galen P, Kennedy JA, Nucera S, Ciceri F, Kaufmann KB, Takayama N, Dobson SM, Trotman-Grant A, Krivdova G, Elzinga J, Mitchell A, ... ... Zandstra PW, et al. miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells. Cancer Cell. 29: 602-606. PMID 27070706 DOI: 10.1016/J.Ccell.2016.03.015 |
0.411 |
|
| 2016 |
Lipsitz YY, Timmins NE, Zandstra PW. Quality cell therapy manufacturing by design. Nature Biotechnology. 34: 393-400. PMID 27054995 DOI: 10.1038/Nbt.3525 |
0.43 |
|
| 2016 |
Rezza A, Wang Z, Sennett R, Qiao W, Wang D, Heitman N, Mok KW, Clavel C, Yi R, Zandstra P, Ma'ayan A, Rendl M. Signaling Networks among Stem Cell Precursors, Transit-Amplifying Progenitors, and their Niche in Developing Hair Follicles. Cell Reports. PMID 27009580 DOI: 10.1016/J.Celrep.2016.02.078 |
0.524 |
|
| 2016 |
Wang Y, Li Y, Thérien-Aubin H, Ma J, Zandstra PW, Kumacheva E. Two-dimensional arrays of cell-laden polymer hydrogel modules. Biomicrofluidics. 10: 014110. PMID 26858822 DOI: 10.1063/1.4940430 |
0.555 |
|
| 2016 |
Lechman ER, Gentner B, Ng SW, Schoof EM, van Galen P, Kennedy JA, Nucera S, Ciceri F, Kaufmann KB, Takayama N, Dobson SM, Trotman-Grant A, Krivdova G, Elzinga J, Mitchell A, ... ... Zandstra PW, et al. miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells. Cancer Cell. PMID 26832662 DOI: 10.1016/J.Ccell.2015.12.011 |
0.379 |
|
| 2016 |
Rezza A, Wang Z, Sennett R, Qiao W, Wang D, Heitman N, Mok K, Clavel C, Yi R, Zandstra P, Ma’ayan A, Rendl M. 701 Signaling networks between stem cell precursors, transit amplifying progenitors, and their niche in developing hair follicles Journal of Investigative Dermatology. 136: S124. DOI: 10.1016/J.Jid.2016.02.743 |
0.509 |
|
| 2015 |
Caldwell J, Wang W, Zandstra PW. Proportional-Integral-Derivative (PID) Control of Secreted Factors for Blood Stem Cell Culture. Plos One. 10: e0137392. PMID 26348930 DOI: 10.1371/Journal.Pone.0137392 |
0.498 |
|
| 2015 |
Onishi K, Zandstra PW. LIF signaling in stem cells and development. Development (Cambridge, England). 142: 2230-6. PMID 26130754 DOI: 10.1242/Dev.117598 |
0.67 |
|
| 2015 |
Hussein SM, Puri MC, Tonge PD, Benevento M, Corso AJ, Clancy JL, Mosbergen R, Li M, Lee DS, Cloonan N, Wood DL, Munoz J, Middleton R, Korn O, Patel HR, ... ... Zandstra PW, et al. Corrigendum: Genome-wide characterization of the routes to pluripotency. Nature. PMID 26083747 DOI: 10.1038/Nature14606 |
0.677 |
|
| 2015 |
Shakiba N, White CA, Lipsitz YY, Yachie-Kinoshita A, Tonge PD, Hussein SM, Puri MC, Elbaz J, Morrissey-Scoot J, Li M, Munoz J, Benevento M, Rogers IM, Hanna JH, Heck AJ, ... ... Zandstra PW, et al. CD24 tracks divergent pluripotent states in mouse and human cells. Nature Communications. 6: 7329. PMID 26076835 DOI: 10.1038/Ncomms8329 |
0.823 |
|
| 2015 |
Qiao W, Zandstra PW. Bringing Blood Stem Cell Phenotype, Genotype, and Function Closer Together. Cell Stem Cell. 16: 574-5. PMID 26046754 DOI: 10.1016/J.Stem.2015.05.001 |
0.595 |
|
| 2015 |
Futrega K, Palmer JS, Kinney M, Lott WB, Ungrin MD, Zandstra PW, Doran MR. The microwell-mesh: A novel device and protocol for the high throughput manufacturing of cartilage microtissues. Biomaterials. 62: 1-12. PMID 26010218 DOI: 10.1016/J.Biomaterials.2015.05.013 |
0.325 |
|
| 2015 |
Bausch-Fluck D, Hofmann A, Bock T, Frei AP, Cerciello F, Jacobs A, Moest H, Omasits U, Gundry RL, Yoon C, Schiess R, Schmidt A, Mirkowska P, Härtlová A, Van Eyk JE, ... ... Zandstra P, et al. A mass spectrometric-derived cell surface protein atlas. Plos One. 10: e0121314. PMID 25894527 DOI: 10.1371/Journal.Pone.0121314 |
0.478 |
|
| 2015 |
Goyal S, Zandstra PW. Stem cells: Chasing blood. Nature. 518: 488-90. PMID 25686602 DOI: 10.1038/Nature14203 |
0.548 |
|
| 2015 |
Lipsitz YY, Zandstra PW. Human pluripotent stem cell process parameter optimization in a small scale suspension bioreactor Bmc Proceedings. 9: O10. DOI: 10.1186/1753-6561-9-S9-O10 |
0.36 |
|
| 2015 |
Thavandiran N, Dubois N, Mikryukov A, Massé S, Beca B, Simmons CA, Deshpande VS, McGarry JP, Chen CS, Nanthakumar K, Keller GM, Radisic M, Zandstra PW. Correction: Design and formulation of functional pluripotent stem cell-derived cardiac microtissues (Proceedings of the National Academy of Sciences (2013) 110, (E4698-E4707) DOI:10.1073/pnas.1311120110) Proceedings of the National Academy of Sciences of the United States of America. 112: E3151. DOI: 10.1073/Pnas.1311120110). |
0.423 |
|
| 2015 |
Chan L, Prowse A, Zandstra PW, Timmins N. Aggregate-based human pluripotent stem cell manufacturing with the ambr®15 platform Cytotherapy. 17: S69-S70. DOI: 10.1016/J.Jcyt.2015.03.544 |
0.543 |
|
| 2015 |
Kim H, Baptista RP, Trampler F, Zandstra PW, Timmins N. Process development towards efficient large-scale manufacturing of an allogenic natural killer cell therapy Cytotherapy. 17: S11-S12. DOI: 10.1016/J.Jcyt.2015.03.323 |
0.355 |
|
| 2014 |
Hussein SM, Puri MC, Tonge PD, Benevento M, Corso AJ, Clancy JL, Mosbergen R, Li M, Lee DS, Cloonan N, Wood DL, Munoz J, Middleton R, Korn O, Patel HR, ... ... Zandstra PW, et al. Genome-wide characterization of the routes to pluripotency. Nature. 516: 198-206. PMID 25503233 DOI: 10.1038/Nature14046 |
0.766 |
|
| 2014 |
Prowse AB, Timmins NE, Yau TM, Li RK, Weisel RD, Keller G, Zandstra PW. Transforming the promise of pluripotent stem cell-derived cardiomyocytes to a therapy: challenges and solutions for clinical trials. The Canadian Journal of Cardiology. 30: 1335-49. PMID 25442434 DOI: 10.1016/J.Cjca.2014.08.005 |
0.511 |
|
| 2014 |
Fares I, Chagraoui J, Gareau Y, Gingras S, Ruel R, Mayotte N, Csaszar E, Knapp DJ, Miller P, Ngom M, Imren S, Roy DC, Watts KL, Kiem HP, Herrington R, ... ... Zandstra PW, et al. Cord blood expansion. Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal. Science (New York, N.Y.). 345: 1509-12. PMID 25237102 DOI: 10.1126/Science.1256337 |
0.607 |
|
| 2014 |
Onishi K, Tonge PD, Nagy A, Zandstra PW. Local BMP-SMAD1 signaling increases LIF receptor-dependent STAT3 responsiveness and primed-to-naive mouse pluripotent stem cell conversion frequency. Stem Cell Reports. 3: 156-68. PMID 25068129 DOI: 10.1016/J.Stemcr.2014.04.019 |
0.674 |
|
| 2014 |
Qiao W, Wang W, Laurenti E, Turinsky AL, Wodak SJ, Bader GD, Dick JE, Zandstra PW. Intercellular network structure and regulatory motifs in the human hematopoietic system. Molecular Systems Biology. 10: 741. PMID 25028490 DOI: 10.15252/Msb.20145141 |
0.572 |
|
| 2014 |
Lücker PB, Javaherian S, Soleas JP, Halverson D, Zandstra PW, McGuigan AP. A microgroove patterned multiwell cell culture plate for high-throughput studies of cell alignment. Biotechnology and Bioengineering. 111: 2537-48. PMID 24889796 DOI: 10.1002/Bit.25298 |
0.561 |
|
| 2014 |
Loring JF, McDevitt TC, Palecek SP, Schaffer DV, Zandstra PW, Nerem RM. A global assessment of stem cell engineering. Tissue Engineering. Part A. 20: 2575-89. PMID 24428577 DOI: 10.1089/Ten.Tea.2013.0468 |
0.697 |
|
| 2014 |
Csaszar E, Chen K, Caldwell J, Chan W, Zandstra PW. Real-time monitoring and control of soluble signaling factors enables enhanced progenitor cell outputs from human cord blood stem cell cultures. Biotechnology and Bioengineering. 111: 1258-64. PMID 24284903 DOI: 10.1002/Bit.25163 |
0.553 |
|
| 2014 |
Csaszar E, Wang W, Usenko T, Qiao W, Delaney C, Bernstein ID, Zandstra PW. Blood stem cell fate regulation by Delta-1-mediated rewiring of IL-6 paracrine signaling. Blood. 123: 650-8. PMID 24243972 DOI: 10.1182/Blood-2013-08-520445 |
0.544 |
|
| 2014 |
DeVeale B, Bausch-Fluck D, Seaberg R, Runciman S, Akbarian V, Karpowicz P, Yoon C, Song H, Leeder R, Zandstra PW, Wollscheid B, van der Kooy D. Surfaceome profiling reveals regulators of neural stem cell function. Stem Cells (Dayton, Ohio). 32: 258-68. PMID 24023036 DOI: 10.1002/Stem.1550 |
0.585 |
|
| 2014 |
Fares I, Chagaroui J, Gareau Y, Gingras S, Mayotte N, Csaszar E, Kiem H, Iscove NN, Humphries RK, Eaves CJ, Cohen S, Marinier A, Zandstra PW, Sauvageau G. Pyrimido-Indole Derivatives Are Novel Agonists of Human Cord Blood Hematopoietic Stem Cell Self-Renewal Blood. 124: 650-650. DOI: 10.1182/Blood.V124.21.650.650 |
0.695 |
|
| 2013 |
Thavandiran N, Dubois N, Mikryukov A, Massé S, Beca B, Simmons CA, Deshpande VS, McGarry JP, Chen CS, Nanthakumar K, Keller GM, Radisic M, Zandstra PW. Design and formulation of functional pluripotent stem cell-derived cardiac microtissues. Proceedings of the National Academy of Sciences of the United States of America. 110: E4698-707. PMID 24255110 DOI: 10.1073/Pnas.1311120110 |
0.395 |
|
| 2013 |
DeVeale B, Brokhman I, Mohseni P, Babak T, Yoon C, Lin A, Onishi K, Tomilin A, Pevny L, Zandstra PW, Nagy A, van der Kooy D. Oct4 is required ~E7.5 for proliferation in the primitive streak. Plos Genetics. 9: e1003957. PMID 24244203 DOI: 10.1371/Journal.Pgen.1003957 |
0.65 |
|
| 2013 |
Nazareth EJ, Ostblom JE, Lücker PB, Shukla S, Alvarez MM, Oh SK, Yin T, Zandstra PW. High-throughput fingerprinting of human pluripotent stem cell fate responses and lineage bias. Nature Methods. 10: 1225-31. PMID 24141495 DOI: 10.1038/Nmeth.2684 |
0.625 |
|
| 2013 |
Stevens KR, Ungrin MD, Schwartz RE, Ng S, Carvalho B, Christine KS, Chaturvedi RR, Li CY, Zandstra PW, Chen CS, Bhatia SN. InVERT molding for scalable control of tissue microarchitecture. Nature Communications. 4: 1847. PMID 23673632 DOI: 10.1038/Ncomms2853 |
0.46 |
|
| 2013 |
Guo H, Isserlin R, Chen X, Wang W, Phanse S, Zandstra PW, Paddison PJ, Emili A. Integrative network analysis of signaling in human CD34(+) hematopoietic progenitor cells by global phosphoproteomic profiling using TiO2 enrichment combined with 2D LC-MS/MS and pathway mapping. Proteomics. 13: 1325-33. PMID 23401153 DOI: 10.1002/Pmic.201200369 |
0.378 |
|
| 2013 |
Csaszar E, Cohen S, Zandstra PW. Blood stem cell products: toward sustainable benchmarks for clinical translation. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 35: 201-10. PMID 23299858 DOI: 10.1002/Bies.201200118 |
0.507 |
|
| 2013 |
Baptista RP, Fluri DA, Zandstra PW. High density continuous production of murine pluripotent cells in an acoustic perfused bioreactor at different oxygen concentrations. Biotechnology and Bioengineering. 110: 648-55. PMID 22949074 DOI: 10.1002/bit.24717 |
0.446 |
|
| 2013 |
Fares I, Chagraoui J, Gareau Y, Gingras S, Rjean R, Csaszar E, Cohen S, Anne M, Zandstra PW, Sauvageau G. UM171 Is a Novel and Potent Agonist Of Human Hematopoietic Stem Cell Renewal Blood. 122: 798-798. DOI: 10.1182/Blood.V122.21.798.798 |
0.523 |
|
| 2013 |
Rahman M, Brauer P, Zúñiga-Pflücker J, Zandstra P. Controlled generation of hematopoietic progenitor cells from pluripotent stem cells using microenvironmental cues Experimental Hematology. 41: S28. DOI: 10.1016/J.Exphem.2013.05.113 |
0.603 |
|
| 2013 |
Hogle LF, Palecek SP, Schaffer D, Zandstra PW. Characterizing international stem cell research niches Regenerative Medicine Ethics: Governing Research and Knowledge Practices. 29-65. DOI: 10.1007/978-1-4614-9062-3_2 |
0.747 |
|
| 2012 |
Onishi K, Tonge PD, Nagy A, Zandstra PW. Microenvironment-mediated reversion of epiblast stem cells by reactivation of repressed JAK-STAT signaling. Integrative Biology : Quantitative Biosciences From Nano to Macro. 4: 1367-76. PMID 22990140 DOI: 10.1039/C2Ib20098H |
0.703 |
|
| 2012 |
Reynolds JG, Geretti E, Hendriks BS, Lee H, Leonard SC, Klinz SG, Noble CO, Lücker PB, Zandstra PW, Drummond DC, Olivier KJ, Nielsen UB, Niyikiza C, Agresta SV, Wickham TJ. HER2-targeted liposomal doxorubicin displays enhanced anti-tumorigenic effects without associated cardiotoxicity. Toxicology and Applied Pharmacology. 262: 1-10. PMID 22676972 DOI: 10.1016/J.Taap.2012.04.008 |
0.387 |
|
| 2012 |
Fluri DA, Tonge PD, Song H, Baptista RP, Shakiba N, Shukla S, Clarke G, Nagy A, Zandstra PW. Derivation, expansion and differentiation of induced pluripotent stem cells in continuous suspension cultures. Nature Methods. 9: 509-16. PMID 22447133 DOI: 10.1038/Nmeth.1939 |
0.826 |
|
| 2012 |
Woodford C, Zandstra PW. Tissue engineering 2.0: guiding self-organization during pluripotent stem cell differentiation. Current Opinion in Biotechnology. 23: 810-9. PMID 22444525 DOI: 10.1016/j.copbio.2012.03.003 |
0.484 |
|
| 2012 |
Moledina F, Clarke G, Oskooei A, Onishi K, Günther A, Zandstra PW. Predictive microfluidic control of regulatory ligand trajectories in individual pluripotent cells. Proceedings of the National Academy of Sciences of the United States of America. 109: 3264-9. PMID 22334649 DOI: 10.1073/Pnas.1111478109 |
0.686 |
|
| 2012 |
Csaszar E, Kirouac DC, Yu M, Wang W, Qiao W, Cooke MP, Boitano AE, Ito C, Zandstra PW. Rapid expansion of human hematopoietic stem cells by automated control of inhibitory feedback signaling. Cell Stem Cell. 10: 218-29. PMID 22305571 DOI: 10.1016/J.Stem.2012.01.003 |
0.602 |
|
| 2012 |
Ungrin MD, Clarke G, Yin T, Niebrugge S, Nostro MC, Sarangi F, Wood G, Keller G, Zandstra PW. Rational bioprocess design for human pluripotent stem cell expansion and endoderm differentiation based on cellular dynamics. Biotechnology and Bioengineering. 109: 853-66. PMID 22139975 DOI: 10.1002/Bit.24375 |
0.543 |
|
| 2012 |
Ishida M, El-Mounayri O, Kattman S, Zandstra P, Sakamoto H, Ogawa M, Keller G, Husain M. Regulated expression and role of c-Myb in the cardiovascular-directed differentiation of mouse embryonic stem cells. Circulation Research. 110: 253-64. PMID 22116818 DOI: 10.1161/Circresaha.111.259499 |
0.489 |
|
| 2012 |
Purpura KA, Bratt-Leal AM, Hammersmith KA, McDevitt TC, Zandstra PW. Systematic engineering of 3D pluripotent stem cell niches to guide blood development. Biomaterials. 33: 1271-80. PMID 22079776 DOI: 10.1016/J.Biomaterials.2011.10.051 |
0.846 |
|
| 2012 |
Parrag IC, Zandstra PW, Woodhouse KA. Fiber alignment and coculture with fibroblasts improves the differentiated phenotype of murine embryonic stem cell-derived cardiomyocytes for cardiac tissue engineering. Biotechnology and Bioengineering. 109: 813-22. PMID 22006660 DOI: 10.1002/Bit.23353 |
0.495 |
|
| 2011 |
Gabut M, Samavarchi-Tehrani P, Wang X, Slobodeniuc V, O'Hanlon D, Sung HK, Alvarez M, Talukder S, Pan Q, Mazzoni EO, Nedelec S, Wichterle H, Woltjen K, Hughes TR, Zandstra PW, et al. An alternative splicing switch regulates embryonic stem cell pluripotency and reprogramming. Cell. 147: 132-46. PMID 21924763 DOI: 10.1016/J.Cell.2011.08.023 |
0.426 |
|
| 2011 |
Matsuura K, Masuda S, Haraguchi Y, Yasuda N, Shimizu T, Hagiwara N, Zandstra PW, Okano T. Creation of mouse embryonic stem cell-derived cardiac cell sheets. Biomaterials. 32: 7355-62. PMID 21807408 DOI: 10.1016/J.Biomaterials.2011.05.042 |
0.57 |
|
| 2011 |
Tumarkin E, Tzadu L, Csaszar E, Seo M, Zhang H, Lee A, Peerani R, Purpura K, Zandstra PW, Kumacheva E. High-throughput combinatorial cell co-culture using microfluidics. Integrative Biology : Quantitative Biosciences From Nano to Macro. 3: 653-62. PMID 21526262 DOI: 10.1039/C1Ib00002K |
0.861 |
|
| 2011 |
Bauwens CL, Song H, Thavandiran N, Ungrin M, Massé S, Nanthakumar K, Seguin C, Zandstra PW. Geometric control of cardiomyogenic induction in human pluripotent stem cells. Tissue Engineering. Part A. 17: 1901-9. PMID 21417693 DOI: 10.1089/Ten.Tea.2010.0563 |
0.512 |
|
| 2011 |
Dengler J, Song H, Thavandiran N, Massé S, Wood GA, Nanthakumar K, Zandstra PW, Radisic M. Engineered heart tissue enables study of residual undifferentiated embryonic stem cell activity in a cardiac environment. Biotechnology and Bioengineering. 108: 704-19. PMID 21246514 DOI: 10.1002/Bit.22987 |
0.502 |
|
| 2011 |
Kumachev A, Greener J, Tumarkin E, Eiser E, Zandstra PW, Kumacheva E. High-throughput generation of hydrogel microbeads with varying elasticity for cell encapsulation. Biomaterials. 32: 1477-83. PMID 21095000 DOI: 10.1016/J.Biomaterials.2010.10.033 |
0.519 |
|
| 2011 |
Bratt-Leal AM, Carpenedo RL, Ungrin MD, Zandstra PW, McDevitt TC. Incorporation of biomaterials in multicellular aggregates modulates pluripotent stem cell differentiation. Biomaterials. 32: 48-56. PMID 20864164 DOI: 10.1016/J.Biomaterials.2010.08.113 |
0.627 |
|
| 2011 |
Csaszar E, Kirouac D, Yu M, Ito C, Zandstra PW. Enhanced Human Hematopoietic Stem Cell Self-Renewal Enabled by Controlling Feedback Signaling From Lineage Committed Cells Blood. 118: 1274-1274. DOI: 10.1182/blood.v118.21.1274.1274 |
0.593 |
|
| 2010 |
Kirouac DC, Ito C, Csaszar E, Roch A, Yu M, Sykes EA, Bader GD, Zandstra PW. Dynamic interaction networks in a hierarchically organized tissue. Molecular Systems Biology. 6: 417. PMID 20924352 DOI: 10.1038/Msb.2010.71 |
0.548 |
|
| 2010 |
Rahman N, Purpura KA, Wylie RG, Zandstra PW, Shoichet MS. The use of vascular endothelial growth factor functionalized agarose to guide pluripotent stem cell aggregates toward blood progenitor cells Biomaterials. 31: 8262-8270. PMID 20684984 DOI: 10.1016/J.Biomaterials.2010.07.040 |
0.853 |
|
| 2010 |
Pompe T, Salchert K, Alberti K, Zandstra P, Werner C. Immobilization of growth factors on solid supports for the modulation of stem cell fate. Nature Protocols. 5: 1042-50. PMID 20539280 DOI: 10.1038/Nprot.2010.70 |
0.527 |
|
| 2010 |
Hewel JA, Liu J, Onishi K, Fong V, Chandran S, Olsen JB, Pogoutse O, Schutkowski M, Wenschuh H, Winkler DF, Eckler L, Zandstra PW, Emili A. Synthetic peptide arrays for pathway-level protein monitoring by liquid chromatography-tandem mass spectrometry. Molecular & Cellular Proteomics : McP. 9: 2460-73. PMID 20467045 DOI: 10.1074/Mcp.M900456-Mcp200 |
0.55 |
|
| 2010 |
Peerani R, Zandstra PW. Enabling stem cell therapies through synthetic stem cell-niche engineering. The Journal of Clinical Investigation. 120: 60-70. PMID 20051637 DOI: 10.1172/Jci41158 |
0.593 |
|
| 2010 |
Ito CY, Kirouac DC, Madlambayan GJ, Yu M, Rogers I, Zandstra PW. The AC133+CD38-, but not the rhodamine-low, phenotype tracks LTC-IC and SRC function in human cord blood ex vivo expansion cultures. Blood. 115: 257-60. PMID 19897585 DOI: 10.1182/Blood-2009-07-228106 |
0.775 |
|
| 2010 |
Song H, Yoon C, Kattman SJ, Dengler J, Massé S, Thavaratnam T, Gewarges M, Nanthakumar K, Rubart M, Keller GM, Radisic M, Zandstra PW. Interrogating functional integration between injected pluripotent stem cell-derived cells and surrogate cardiac tissue. Proceedings of the National Academy of Sciences of the United States of America. 107: 3329-34. PMID 19846783 DOI: 10.1073/Pnas.0905729106 |
0.479 |
|
| 2009 |
Peerani R, Onishi K, Mahdavi A, Kumacheva E, Zandstra PW. Manipulation of signaling thresholds in "engineered stem cell niches" identifies design criteria for pluripotent stem cell screens. Plos One. 4: e6438. PMID 19649273 DOI: 10.1371/Journal.Pone.0006438 |
0.814 |
|
| 2009 |
Kirouac DC, Madlambayan GJ, Yu M, Sykes EA, Ito C, Zandstra PW. Cell-cell interaction networks regulate blood stem and progenitor cell fate. Molecular Systems Biology. 5: 293. PMID 19638974 DOI: 10.1038/Msb.2009.49 |
0.839 |
|
| 2009 |
Discher DE, Mooney DJ, Zandstra PW. Growth factors, matrices, and forces combine and control stem cells. Science (New York, N.Y.). 324: 1673-7. PMID 19556500 DOI: 10.1126/Science.1171643 |
0.522 |
|
| 2009 |
Csaszar E, Gavigan G, Ungrin M, Thérien C, Dubé P, Féthière J, Sauvageau G, Roy DC, Zandstra PW. An automated system for delivery of an unstable transcription factor to hematopoietic stem cell cultures. Biotechnology and Bioengineering. 103: 402-12. PMID 19266473 DOI: 10.1002/Bit.22297 |
0.558 |
|
| 2009 |
Ellis J, Bruneau BG, Keller G, Lemischka IR, Nagy A, Rossant J, Srivastava D, Zandstra PW, Stanford WL. Alternative induced pluripotent stem cell characterization criteria for in vitro applications. Cell Stem Cell. 4: 198-9; author reply . PMID 19265656 DOI: 10.1016/J.Stem.2009.02.010 |
0.517 |
|
| 2009 |
Zandstra PW. Pairing cells to enhance fusion. Nature Methods. 6: 123-4. PMID 19180092 DOI: 10.1038/Nmeth0209-123 |
0.433 |
|
| 2009 |
Peerani R, Bauwens C, Kumacheva E, Zandstra PW. Patterning mouse and human embryonic stem cells using micro-contact printing. Methods in Molecular Biology (Clifton, N.J.). 482: 21-33. PMID 19089347 DOI: 10.1007/978-1-59745-060-7_2 |
0.6 |
|
| 2009 |
Niebruegge S, Bauwens CL, Peerani R, Thavandiran N, Masse S, Sevaptisidis E, Nanthakumar K, Woodhouse K, Husain M, Kumacheva E, Zandstra PW. Generation of human embryonic stem cell-derived mesoderm and cardiac cells using size-specified aggregates in an oxygen-controlled bioreactor. Biotechnology and Bioengineering. 102: 493-507. PMID 18767184 DOI: 10.1002/Bit.22065 |
0.539 |
|
| 2008 |
Kirouac DC, Zandstra PW. The systematic production of cells for cell therapies. Cell Stem Cell. 3: 369-81. PMID 18940729 DOI: 10.1016/j.stem.2008.09.001 |
0.46 |
|
| 2008 |
Purpura KA, George SH, Dang SM, Choi K, Nagy A, Zandstra PW. Soluble Flt-1 regulates Flk-1 activation to control hematopoietic and endothelial development in an oxygen-responsive manner. Stem Cells (Dayton, Ohio). 26: 2832-42. PMID 18772315 DOI: 10.1634/Stemcells.2008-0237 |
0.799 |
|
| 2008 |
Coles-Takabe BL, Brain I, Purpura KA, Karpowicz P, Zandstra PW, Morshead CM, van der Kooy D. Don't look: growing clonal versus nonclonal neural stem cell colonies. Stem Cells (Dayton, Ohio). 26: 2938-44. PMID 18757294 DOI: 10.1634/Stemcells.2008-0558 |
0.857 |
|
| 2008 |
Bauwens CL, Peerani R, Niebruegge S, Woodhouse KA, Kumacheva E, Husain M, Zandstra PW. Control of human embryonic stem cell colony and aggregate size heterogeneity influences differentiation trajectories. Stem Cells (Dayton, Ohio). 26: 2300-10. PMID 18583540 DOI: 10.1634/Stemcells.2008-0183 |
0.439 |
|
| 2008 |
Varelas X, Sakuma R, Samavarchi-Tehrani P, Peerani R, Rao BM, Dembowy J, Yaffe MB, Zandstra PW, Wrana JL. TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal. Nature Cell Biology. 10: 837-48. PMID 18568018 DOI: 10.1038/Ncb1748 |
0.301 |
|
| 2008 |
Alberti K, Davey RE, Onishi K, George S, Salchert K, Seib FP, Bornhäuser M, Pompe T, Nagy A, Werner C, Zandstra PW. Functional immobilization of signaling proteins enables control of stem cell fate. Nature Methods. 5: 645-50. PMID 18552855 DOI: 10.1038/Nmeth.1222 |
0.657 |
|
| 2008 |
Purpura KA, Morin J, Zandstra PW. Analysis of the temporal and concentration-dependent effects of BMP-4, VEGF, and TPO on development of embryonic stem cell-derived mesoderm and blood progenitors in a defined, serum-free media. Experimental Hematology. 36: 1186-98. PMID 18550259 DOI: 10.1016/J.Exphem.2008.04.003 |
0.852 |
|
| 2008 |
Fromstein JD, Zandstra PW, Alperin C, Rockwood D, Rabolt JF, Woodhouse KA. Seeding bioreactor-produced embryonic stem cell-derived cardiomyocytes on different porous, degradable, polyurethane scaffolds reveals the effect of scaffold architecture on cell morphology. Tissue Engineering. Part A. 14: 369-78. PMID 18333789 DOI: 10.1089/Tea.2006.0410 |
0.542 |
|
| 2008 |
Ungrin MD, Joshi C, Nica A, Bauwens C, Zandstra PW. Reproducible, ultra high-throughput formation of multicellular organization from single cell suspension-derived human embryonic stem cell aggregates. Plos One. 3: e1565. PMID 18270562 DOI: 10.1371/journal.pone.0001565 |
0.512 |
|
| 2008 |
Wang W, Horner DN, Chen WL, Zandstra PW, Audet J. Synergy between erythropoietin and stem cell factor during erythropoiesis can be quantitatively described without co-signaling effects. Biotechnology and Bioengineering. 99: 1261-72. PMID 17969148 DOI: 10.1002/Bit.21677 |
0.837 |
|
| 2007 |
Ungrin M, O'Connor M, Eaves C, Zandstra PW. Phenotypic analysis of human embryonic stem cells. Current Protocols in Stem Cell Biology. Unit 1B.3. PMID 18785161 DOI: 10.1002/9780470151808.Sc01B03S2 |
0.65 |
|
| 2007 |
Walker E, Ohishi M, Davey RE, Zhang W, Cassar PA, Tanaka TS, Der SD, Morris Q, Hughes TR, Zandstra PW, Stanford WL. Prediction and testing of novel transcriptional networks regulating embryonic stem cell self-renewal and commitment. Cell Stem Cell. 1: 71-86. PMID 18371337 DOI: 10.1016/J.Stem.2007.04.002 |
0.441 |
|
| 2007 |
Peerani R, Rao BM, Bauwens C, Yin T, Wood GA, Nagy A, Kumacheva E, Zandstra PW. Niche-mediated control of human embryonic stem cell self-renewal and differentiation. The Embo Journal. 26: 4744-55. PMID 17948051 DOI: 10.1038/Sj.Emboj.7601896 |
0.423 |
|
| 2007 |
Mahdavi A, Davey RE, Bhola P, Yin T, Zandstra PW. Sensitivity analysis of intracellular signaling pathway kinetics predicts targets for stem cell fate control. Plos Computational Biology. 3: e130. PMID 17616983 DOI: 10.1371/Journal.Pcbi.0030130 |
0.673 |
|
| 2007 |
Baksh D, Zandstra PW, Davies JE. A non-contact suspension culture approach to the culture of osteogenic cells derived from a CD49elow subpopulation of human bone marrow-derived cells. Biotechnology and Bioengineering. 98: 1195-208. PMID 17614333 DOI: 10.1002/Bit.21556 |
0.488 |
|
| 2007 |
Alperin C, Zandstra PW, Woodhouse KA. Engineering cardiac healing using embryonic stem cell-derived cardiac cell seeded constructs. Frontiers in Bioscience : a Journal and Virtual Library. 12: 3694-712. PMID 17485332 DOI: 10.2741/2345 |
0.499 |
|
| 2007 |
Davey RE, Onishi K, Mahdavi A, Zandstra PW. LIF-mediated control of embryonic stem cell self-renewal emerges due to an autoregulatory loop. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 2020-32. PMID 17356004 DOI: 10.1096/Fj.06-7852Com |
0.794 |
|
| 2006 |
Madlambayan GJ, Rogers I, Purpura KA, Ito C, Yu M, Kirouac D, Casper RF, Zandstra PW. Clinically relevant expansion of hematopoietic stem cells with conserved function in a single-use, closed-system bioprocess. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 12: 1020-30. PMID 17084368 DOI: 10.1016/J.Bbmt.2006.07.005 |
0.855 |
|
| 2006 |
Kirouac DC, Zandstra PW. Understanding cellular networks to improve hematopoietic stem cell expansion cultures. Current Opinion in Biotechnology. 17: 538-47. PMID 16899360 DOI: 10.1016/J.Copbio.2006.07.003 |
0.622 |
|
| 2006 |
Davey RE, Zandstra PW. Spatial organization of embryonic stem cell responsiveness to autocrine gp130 ligands reveals an autoregulatory stem cell niche. Stem Cells (Dayton, Ohio). 24: 2538-48. PMID 16825607 DOI: 10.1634/Stemcells.2006-0216 |
0.611 |
|
| 2005 |
Madlambayan GJ, Rogers I, Kirouac DC, Yamanaka N, Mazurier F, Doedens M, Casper RF, Dick JE, Zandstra PW. Dynamic changes in cellular and microenvironmental composition can be controlled to elicit in vitro human hematopoietic stem cell expansion. Experimental Hematology. 33: 1229-39. PMID 16219546 DOI: 10.1016/J.Exphem.2005.05.018 |
0.824 |
|
| 2005 |
Rosu-Myles M, Stewart E, Trowbridge J, Ito CY, Zandstra P, Bhatia M. A unique population of bone marrow cells migrates to skeletal muscle via hepatocyte growth factor/c-met axis. Journal of Cell Science. 118: 4343-52. PMID 16144866 DOI: 10.1242/Jcs.02555 |
0.474 |
|
| 2005 |
Rao BM, Zandstra PW. Culture development for human embryonic stem cell propagation: Molecular aspects and challenges Current Opinion in Biotechnology. 16: 568-576. PMID 16099157 DOI: 10.1016/J.Copbio.2005.08.001 |
0.449 |
|
| 2005 |
Fok EY, Zandstra PW. Shear-controlled single-step mouse embryonic stem cell expansion and embryoid body-based differentiation. Stem Cells (Dayton, Ohio). 23: 1333-42. PMID 16081660 DOI: 10.1634/stemcells.2005-0112 |
0.466 |
|
| 2005 |
Baksh D, Davies JE, Zandstra PW. Soluble factor cross-talk between human bone marrow-derived hematopoietic and mesenchymal cells enhances in vitro CFU-F and CFU-O growth and reveals heterogeneity in the mesenchymal progenitor cell compartment. Blood. 106: 3012-9. PMID 16030193 DOI: 10.1182/Blood-2005-01-0433 |
0.525 |
|
| 2005 |
Alperin C, Zandstra PW, Woodhouse KA. Polyurethane films seeded with embryonic stem cell-derived cardiomyocytes for use in cardiac tissue engineering applications. Biomaterials. 26: 7377-86. PMID 16023195 DOI: 10.1016/J.Biomaterials.2005.05.064 |
0.398 |
|
| 2005 |
Viswanathan S, Davey RE, Cheng D, Raghu RC, Lauffenburger DA, Zandstra PW. Clonal evolution of stem and differentiated cells can be predicted by integrating cell-intrinsic and -extrinsic parameters. Biotechnology and Applied Biochemistry. 42: 119-31. PMID 15882145 DOI: 10.1042/Ba20040207 |
0.776 |
|
| 2005 |
Bauwens C, Yin T, Dang S, Peerani R, Zandstra PW. Development of a perfusion fed bioreactor for embryonic stem cell-derived cardiomyocyte generation: oxygen-mediated enhancement of cardiomyocyte output. Biotechnology and Bioengineering. 90: 452-61. PMID 15778986 DOI: 10.1002/Bit.20445 |
0.713 |
|
| 2005 |
Dang SM, Zandstra PW. Scalable production of embryonic stem cell-derived cells. Methods in Molecular Biology (Clifton, N.J.). 290: 353-64. PMID 15361674 DOI: 10.1385/1-59259-838-2:353 |
0.784 |
|
| 2005 |
Mahdavi A, Davey RE, Bhola P, Yin T, Zandstra PW. Analysis Of Intracellular Signaling Kinetics Predicts Presentation Modes And Targets For Stem Cell Fate Control Plos Computational Biology. DOI: 10.1371/Journal.Pcbi.0030130.Eor |
0.686 |
|
| 2004 |
Chang KH, Zandstra PW. Quantitative screening of embryonic stem cell differentiation: endoderm formation as a model. Biotechnology and Bioengineering. 88: 287-98. PMID 15486933 DOI: 10.1002/Bit.20242 |
0.576 |
|
| 2004 |
Zandstra PW. The opportunity of stem cell bioengineering. Biotechnology and Bioengineering. 88: 263. PMID 15486929 DOI: 10.1002/Bit.20303 |
0.604 |
|
| 2004 |
Davey RE, Zandstra PW. Signal processing underlying extrinsic control of stem cell fate. Current Opinion in Hematology. 11: 95-101. PMID 15257025 DOI: 10.1097/01.Moh.0000133650.68744.0C |
0.584 |
|
| 2004 |
Dang SM, Gerecht-Nir S, Chen J, Itskovitz-Eldor J, Zandstra PW. Controlled, scalable embryonic stem cell differentiation culture. Stem Cells (Dayton, Ohio). 22: 275-82. PMID 15153605 DOI: 10.1634/stemcells.22-3-275 |
0.768 |
|
| 2004 |
Prudhomme W, Daley GQ, Zandstra P, Lauffenburger DA. Multivariate proteomic analysis of murine embryonic stem cell self-renewal versus differentiation signaling. Proceedings of the National Academy of Sciences of the United States of America. 101: 2900-5. PMID 14978270 DOI: 10.1073/Pnas.0308768101 |
0.726 |
|
| 2004 |
Purpura KA, Aubin JE, Zandstra PW. Sustained in vitro expansion of bone progenitors is cell density dependent. Stem Cells (Dayton, Ohio). 22: 39-50. PMID 14688390 DOI: 10.1634/Stemcells.22-1-39 |
0.842 |
|
| 2004 |
Vergidis J, Suck G, Wang X, Zandstra PW, Keating A. Culture Conditions for Generating Human Bone Marrow Stromal Cells Influence Cell Immunophenotype and In Vivo Biodistribution in Immune Deficient Mice. Blood. 104: 2334-2334. DOI: 10.1182/Blood.V104.11.2334.2334 |
0.486 |
|
| 2004 |
Madlambayan GJ, Baksh D, Zandstra PW. Systematic Approach to the Development of Stem Cell Expansion Cultures Handbook of Stem Cells. 2: 663-676. DOI: 10.1016/B978-012436643-5/50149-8 |
0.822 |
|
| 2004 |
Alperin C, Zandstra PW, Bauwens C, Woodhouse KA. Embryonic stem cell-derived cardiomyocytes cultured on biodegradable polyurethane scaffolds Transactions - 7th World Biomaterials Congress. 471. |
0.504 |
|
| 2003 |
Viswanathan S, Zandstra PW. Towards predictive models of stem cell fate. Cytotechnology. 41: 75-92. PMID 19002945 DOI: 10.1023/A:1024866504538 |
0.735 |
|
| 2003 |
Viswanathan S, Benatar T, Mileikovsky M, Lauffenburger DA, Nagy A, Zandstra PW. Supplementation-dependent differences in the rates of embryonic stem cell self-renewal, differentiation, and apoptosis. Biotechnology and Bioengineering. 84: 505-17. PMID 14574685 DOI: 10.1002/Bit.10799 |
0.768 |
|
| 2003 |
Zandstra PW, Bauwens C, Yin T, Liu Q, Schiller H, Zweigerdt R, Pasumarthi KBS, Field LJ. Scalable production of embryonic stem cell-derived cardiomyocytes Tissue Engineering. 9: 767-778. PMID 13678453 DOI: 10.1089/107632703768247449 |
0.469 |
|
| 2003 |
Purpura KA, Zandstra PW, Aubin JE. Fluorescence activated cell sorting reveals heterogeneous and cell non-autonomous osteoprogenitor differentiation in fetal rat calvaria cell populations. Journal of Cellular Biochemistry. 90: 109-20. PMID 12938161 DOI: 10.1002/Jcb.10596 |
0.826 |
|
| 2003 |
Baksh D, Davies JE, Zandstra PW. Adult human bone marrow-derived mesenchymal progenitor cells are capable of adhesion-independent survival and expansion. Experimental Hematology. 31: 723-32. PMID 12901978 DOI: 10.1016/S0301-472X(03)00106-1 |
0.521 |
|
| 2003 |
Purpura KA, Aubin JE, Zandstra PW. Two-color image analysis discriminates between mineralized and unmineralized bone nodules in vitro. Biotechniques. 34: 1188-92, 1194, 1196 . PMID 12813887 DOI: 10.2144/03346St02 |
0.784 |
|
| 2002 |
Madras N, Gibbs AL, Zhou Y, Zandstra PW, Aubin JE. Modeling stem cell development by retrospective analysis of gene expression profiles in single progenitor-derived colonies. Stem Cells (Dayton, Ohio). 20: 230-40. PMID 12004081 DOI: 10.1634/Stemcells.20-3-230 |
0.57 |
|
| 2002 |
Dang SM, Kyba M, Perlingeiro R, Daley GQ, Zandstra PW. Efficiency of embryoid body formation and hematopoietic development from embryonic stem cells in different culture systems. Biotechnology and Bioengineering. 78: 442-53. PMID 11948451 DOI: 10.1002/Bit.10220 |
0.799 |
|
| 2002 |
Viswanathan S, Benatar T, Rose-John S, Lauffenburger DA, Zandstra PW. Ligand/receptor signaling threshold (LIST) model accounts for gp130-mediated embryonic stem cell self-renewal responses to LIF and HIL-6. Stem Cells (Dayton, Ohio). 20: 119-38. PMID 11897869 DOI: 10.1634/Stemcells.20-2-119 |
0.745 |
|
| 2002 |
Bauwens C, Yin T, Liu Q, Zandstra PW. Scalable generation of cardiomyocytes from mouse embryonic stem cells Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 1: 745. |
0.459 |
|
| 2002 |
Madlambayan GJ, Baksh D, Rogers I, Casper RF, Davies JE, Zandstra PW. Manipulation of adult bone marrow derived stem and progenitor cell population dynamics in suspension culture Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 1: 881. |
0.773 |
|
| 2001 |
Madlambayan GJ, Rogers I, Casper RF, Zandstra PW. Controlling culture dynamics for the expansion of hematopoietic stem cells. Journal of Hematotherapy & Stem Cell Research. 10: 481-92. PMID 11522231 DOI: 10.1089/15258160152509091 |
0.837 |
|
| 2001 |
Zandstra PW, Nagy A. Stem cell bioengineering Annual Review of Biomedical Engineering. 3: 275-305. PMID 11447065 DOI: 10.1146/Annurev.Bioeng.3.1.275 |
0.565 |
|
| 2000 |
Eaves C, Zandstra P, Conneally E, Miller C, Cashman J, Petzer A, Piret J. Changes in the cytokine regulation of stem cell self-renewal during ontogeny. Stem Cells (Dayton, Ohio). 177-84. PMID 11012160 DOI: 10.1002/Stem.5530160821 |
0.802 |
|
| 2000 |
Zandstra PW, Lauffenburger DA, Eaves CJ. A ligand-receptor signaling threshold model of stem cell differentiation control: A biologically conserved mechanism applicable to hematopoiesis Blood. 96: 1215-1222. PMID 10942360 DOI: 10.1182/Blood.V96.4.1215.H8001215_1215_1222 |
0.728 |
|
| 2000 |
Zandstra PW, Le HV, Daley GQ, Griffith LG, Lauffenburger DA. Leukemia inhibitory factor (LIF) concentration modulates embryonic stem cell self-renewal and differentiation independently of proliferation. Biotechnology and Bioengineering. 69: 607-17. PMID 10918135 DOI: 10.1002/1097-0290(20000920)69:6<607::Aid-Bit4>3.0.Co;2-F |
0.836 |
|
| 2000 |
Viswanathan S, Benatar TC, Rose-John S, Lauffenburger DA, Zandstra PW. Threshold-dependent regulation of stem cell fate: a developmentally conserved mechanism applicable to hematopoiesis Blood. 96. |
0.528 |
|
| 1999 |
Eaves C, Miller C, Conneally E, Audet J, Oostendorp R, Cashman J, Zandstra P, Rose-John S, Piret J, Eaves A. Introduction to stem cell biology in vitro. Threshold to the future. Annals of the New York Academy of Sciences. 872: 1-8. PMID 10372105 DOI: 10.1111/J.1749-6632.1999.Tb08447.X |
0.872 |
|
| 1999 |
Zandstra PW, Jervis E, Haynes CA, Kilburn DG, Eaves CJ, Piret JM. Concentration-dependent internalization of a cytokine/cytokine receptor complex in human hematopoietic cells. Biotechnology and Bioengineering. 63: 493-501. PMID 10099630 DOI: 10.1002/(Sici)1097-0290(19990520)63:4<493::Aid-Bit13>3.0.Co;2-0 |
0.78 |
|
| 1998 |
Zandstra PW, Conneally E, Piret JM, Eaves CJ. Ontogeny-associated changes in the cytokine responses of primitive human haemopoietic cells. British Journal of Haematology. 101: 770-8. PMID 9674754 DOI: 10.1046/j.1365-2141.1998.00777.x |
0.516 |
|
| 1998 |
Audet J, Zandstra PW, Eaves CJ, Piret JM. Advances in hematopoietic stem cell culture. Current Opinion in Biotechnology. 9: 146-51. PMID 9588003 DOI: 10.1016/S0958-1669(98)80107-9 |
0.859 |
|
| 1997 |
Zandstra PW, Petzer AL, Eaves CJ, Piret JM. Cellular determinants affecting the rate of cytokine in cultures of human hematopoietic cells. Biotechnology and Bioengineering. 54: 58-66. PMID 18634073 DOI: 10.1002/(Sici)1097-0290(19970405)54:1<58::Aid-Bit7>3.0.Co;2-X |
0.75 |
|
| 1997 |
Eaves C, Miller C, Cashman J, Conneally I, Petzer A, Zandstra P, Eaves A, Kaushansky K, Moore MAS, Dick JE, Lansdorp PM. Hematopoietic stem cells: Inferences from in vivo assays Stem Cells. 15: 1-5. PMID 9368318 DOI: 10.1002/Stem.5530150802 |
0.663 |
|
| 1997 |
Zandstra PW, Conneally E, Petzer AL, Piret JM, Eaves CJ. Cytokine manipulation of primitive human hematopoietic cell self-renewal. Proceedings of the National Academy of Sciences of the United States of America. 94: 4698-703. PMID 9114054 DOI: 10.1073/Pnas.94.9.4698 |
0.724 |
|
| 1997 |
Zandstra PW, Petzer AL, Eaves CJ, Piret JM. Cellular determinants affecting the rate of cytokine depletion in cultures of human hematopoietic cells Biotechnology and Bioengineering. 54: 58-66. DOI: 10.1002/(SICI)1097-0290(19970405)54:1<58::AID-BIT7>3.0.CO;2-X |
0.416 |
|
| 1996 |
Petzer AL, Zandstra PW, Piret JM, Eaves CJ. Differential cytokine effects on primitive (CD34+CD38-) human hematopoietic cells: novel responses to Flt3-ligand and thrombopoietin. The Journal of Experimental Medicine. 183: 2551-8. PMID 8676076 DOI: 10.1084/Jem.183.6.2551 |
0.69 |
|
| 1994 |
Zandstra PW, Eaves CJ, Piret JM. Expansion of hematopoietic progenitor cell populations in stirred suspension bioreactors of normal human bone marrow cells. Bio/Technology (Nature Publishing Company). 12: 909-14. PMID 7521647 DOI: 10.1038/Nbt0994-909 |
0.748 |
|
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