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Fraydoon Rastinejad - Publications

Affiliations: 
University of Virginia, Charlottesville, VA 
Area:
Pharmacology, Medical Biophysics, Biochemistry
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47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Zhuang J, Shang Q, Rastinejad F, Wu D. Decoding Allosteric Control in Hypoxia-Inducible Factors. Journal of Molecular Biology. 168352. PMID 37935255 DOI: 10.1016/j.jmb.2023.168352  0.386
2023 Rastinejad F. The protein architecture and allosteric landscape of HNF4α. Frontiers in Endocrinology. 14: 1219092. PMID 37732120 DOI: 10.3389/fendo.2023.1219092  0.451
2023 Ondrová K, Zůvalová I, Vyhlídalová B, Krasulová K, Miková E, Vrzal R, Nádvorník P, Nepal B, Kortagere S, Kopečná M, Kopečný D, Šebela M, Rastinejad F, Pu H, Soural M, et al. Monoterpenoid aryl hydrocarbon receptor allosteric antagonists protect against ultraviolet skin damage in female mice. Nature Communications. 14: 2728. PMID 37169746 DOI: 10.1038/s41467-023-38478-6  0.4
2022 Sun X, Jing L, Li F, Zhang M, Diao X, Zhuang J, Rastinejad F, Wu D. Structures of NPAS4-ARNT and NPAS4-ARNT2 heterodimers reveal new dimerization modalities in the bHLH-PAS transcription factor family. Proceedings of the National Academy of Sciences of the United States of America. 119: e2208804119. PMID 36343253 DOI: 10.1073/pnas.2208804119  0.353
2022 Rastinejad F. Retinoic acid receptor structures: the journey from single domains to the full-length complex. Journal of Molecular Endocrinology. PMID 36069789 DOI: 10.1530/JME-22-0113  0.484
2018 Daniel B, Nagy G, Czimmerer Z, Horvath A, Hammers DW, Cuaranta-Monroy I, Poliska S, Tzerpos P, Kolostyak Z, Hays TT, Patsalos A, Houtman R, Sauer S, Francois-Deleuze J, Rastinejad F, et al. The Nuclear Receptor PPARγ Controls Progressive Macrophage Polarization as a Ligand-Insensitive Epigenomic Ratchet of Transcriptional Memory. Immunity. 49: 615-626.e6. PMID 30332629 DOI: 10.1016/J.Immuni.2018.09.005  0.313
2017 Chandra V, Wu D, Li S, Potluri N, Kim Y, Rastinejad F. The quaternary architecture of RARβ-RXRα heterodimer facilitates domain-domain signal transmission. Nature Communications. 8: 868. PMID 29021580 DOI: 10.1038/s41467-017-00981-y  0.443
2016 Wu D, Su X, Potluri N, Kim Y, Rastinejad F. NPAS1-ARNT and NPAS3-ARNT crystal structures implicate the bHLH-PAS family as multi-ligand binding transcription factors. Elife. 5. PMID 27782878 DOI: 10.7554/eLife.18790  0.473
2016 Wu D, Rastinejad F. Structural characterization of mammalian bHLH-PAS transcription factors. Current Opinion in Structural Biology. 43: 1-9. PMID 27721191 DOI: 10.1016/j.sbi.2016.09.011  0.316
2016 Khorasanizadeh S, Rastinejad F. Visualizing the Architectures and Interactions of Nuclear Receptors. Endocrinology. en20161559. PMID 27704949 DOI: 10.1210/en.2016-1559  0.45
2015 Santori FR, Huang P, van de Pavert SA, Douglass EF, Leaver DJ, Haubrich BA, Keber R, Lorbek G, Konijn T, Rosales BN, Rozman D, Horvat S, Rahier A, Mebius RE, Rastinejad F, et al. Identification of natural RORγ ligands that regulate the development of lymphoid cells. Cell Metabolism. 21: 286-97. PMID 25651181 DOI: 10.1016/J.Cmet.2015.01.004  0.309
2015 Rastinejad F, Ollendorff V, Polikarpov I. Nuclear receptor full-length architectures: confronting myth and illusion with high resolution. Trends in Biochemical Sciences. 40: 16-24. PMID 25435400 DOI: 10.1016/j.tibs.2014.10.011  0.483
2013 Rastinejad F, Huang P, Chandra V, Khorasanizadeh S. Understanding nuclear receptor form and function using structural biology. Journal of Molecular Endocrinology. 51: T1-T21. PMID 24103914 DOI: 10.1530/JME-13-0173  0.527
2013 Wu D, Potluri N, Kim Y, Rastinejad F. Structure and dimerization properties of the aryl hydrocarbon receptor PAS-A domain. Molecular and Cellular Biology. 33: 4346-56. PMID 24001774 DOI: 10.1128/MCB.00698-13  0.414
2013 Chandra V, Huang P, Potluri N, Wu D, Kim Y, Rastinejad F. Multidomain integration in the structure of the HNF-4α nuclear receptor complex. Nature. 495: 394-8. PMID 23485969 DOI: 10.1038/nature11966  0.486
2010 Kim D, Blus BJ, Chandra V, Huang P, Rastinejad F, Khorasanizadeh S. Corecognition of DNA and a methylated histone tail by the MSL3 chromodomain. Nature Structural & Molecular Biology. 17: 1027-9. PMID 20657587 DOI: 10.1038/Nsmb.1856  0.372
2010 Huang P, Chandra V, Rastinejad F. Structural overview of the nuclear receptor superfamily: insights into physiology and therapeutics. Annual Review of Physiology. 72: 247-72. PMID 20148675 DOI: 10.1146/Annurev-Physiol-021909-135917  0.468
2008 Chandra V, Huang P, Hamuro Y, Raghuram S, Wang Y, Burris TP, Rastinejad F. Structure of the intact PPAR-gamma-RXR- nuclear receptor complex on DNA. Nature. 456: 350-6. PMID 19043829 DOI: 10.1038/Nature07413  0.747
2007 Raghuram S, Stayrook KR, Huang P, Rogers PM, Nosie AK, McClure DB, Burris LL, Khorasanizadeh S, Burris TP, Rastinejad F. Identification of heme as the ligand for the orphan nuclear receptors REV-ERBalpha and REV-ERBbeta. Nature Structural & Molecular Biology. 14: 1207-13. PMID 18037887 DOI: 10.1038/Nsmb1344  0.677
2007 Flanagan JF, Blus BJ, Kim D, Clines KL, Rastinejad F, Khorasanizadeh S. Molecular implications of evolutionary differences in CHD double chromodomains. Journal of Molecular Biology. 369: 334-42. PMID 17433364 DOI: 10.1016/J.Jmb.2007.03.024  0.382
2005 Flanagan JF, Mi LZ, Chruszcz M, Cymborowski M, Clines KL, Kim Y, Minor W, Rastinejad F, Khorasanizadeh S. Double chromodomains cooperate to recognize the methylated histone H3 tail. Nature. 438: 1181-5. PMID 16372014 DOI: 10.1038/Nature04290  0.598
2005 Wright CS, Mi LZ, Lee S, Rastinejad F. Crystal structure analysis of phosphatidylcholine-GM2-activator product complexes: evidence for hydrolase activity. Biochemistry. 44: 13510-21. PMID 16216074 DOI: 10.1021/Bi050668W  0.584
2004 Wright CS, Mi LZ, Rastinejad F. Evidence for lipid packaging in the crystal structure of the GM2-activator complex with platelet activating factor. Journal of Molecular Biology. 342: 585-92. PMID 15327957 DOI: 10.1016/J.Jmb.2004.07.063  0.62
2004 Ahvazi B, Boeshans KM, Rastinejad F. The emerging structural understanding of transglutaminase 3. Journal of Structural Biology. 147: 200-7. PMID 15193648 DOI: 10.1016/J.Jsb.2004.03.009  0.389
2004 Orlowski M, Szyszka M, Kowalska A, Grad I, Zoglowek A, Rymarczyk G, Dobryszycki P, Krowarsch D, Rastinejad F, Kochman M, Ozyhar A. Plasticity of the ecdysone receptor DNA binding domain. Molecular Endocrinology (Baltimore, Md.). 18: 2166-84. PMID 15192079 DOI: 10.1210/me.2004-0154  0.561
2004 Ahvazi B, Boeshans KM, Idler W, Baxa U, Steinert PM, Rastinejad F. Structural basis for the coordinated regulation of transglutaminase 3 by guanine nucleotides and calcium/magnesium. The Journal of Biological Chemistry. 279: 7180-92. PMID 14645372 DOI: 10.1074/jbc.M312310200  0.304
2003 Devarakonda S, Harp JM, Kim Y, Ozyhar A, Rastinejad F. Structure of the heterodimeric ecdysone receptor DNA-binding complex. The Embo Journal. 22: 5827-40. PMID 14592980 DOI: 10.1093/Emboj/Cdg569  0.773
2003 Elkins PA, Watts JM, Zalacain M, van Thiel A, Vitazka PR, Redlak M, Andraos-Selim C, Rastinejad F, Holmes WM. Insights into catalysis by a knotted TrmD tRNA methyltransferase. Journal of Molecular Biology. 333: 931-49. PMID 14583191 DOI: 10.1016/J.Jmb.2003.09.011  0.469
2003 Wright CS, Zhao Q, Rastinejad F. Structural analysis of lipid complexes of GM2-activator protein. Journal of Molecular Biology. 331: 951-64. PMID 12909021 DOI: 10.1016/S0022-2836(03)00794-0  0.323
2003 Mi LZ, Devarakonda S, Harp JM, Han Q, Pellicciari R, Willson TM, Khorasanizadeh S, Rastinejad F. Structural basis for bile acid binding and activation of the nuclear receptor FXR. Molecular Cell. 11: 1093-100. PMID 12718893 DOI: 10.1016/S1097-2765(03)00112-6  0.731
2002 Jacobs SA, Harp JM, Devarakonda S, Kim Y, Rastinejad F, Khorasanizadeh S. The active site of the SET domain is constructed on a knot. Nature Structural Biology. 9: 833-8. PMID 12389038 DOI: 10.1038/Nsb861  0.663
2002 Holaska JM, Black BE, Rastinejad F, Paschal BM. Ca2+-dependent nuclear export mediated by calreticulin. Molecular and Cellular Biology. 22: 6286-97. PMID 12167720 DOI: 10.1128/Mcb.22.17.6286-6297.2002  0.353
2001 Black BE, Holaska JM, Rastinejad F, Paschal BM. DNA binding domains in diverse nuclear receptors function as nuclear export signals. Current Biology : Cb. 11: 1749-58. PMID 11719216 DOI: 10.1016/S0960-9822(01)00537-1  0.547
2001 Sierk ML, Zhao Q, Rastinejad F. DNA deformability as a recognition feature in the reverb response element. Biochemistry. 40: 12833-43. PMID 11669620 DOI: 10.1021/Bi011086R  0.741
2001 Chasse SA, Rastinejad F. Physical structure of nuclear receptor-DNA complexes. Methods in Molecular Biology (Clifton, N.J.). 176: 91-103. PMID 11554341 DOI: 10.1385/1-59259-115-9:91  0.509
2001 Mi LZ, Rastinejad F. Large scale production of nuclear receptor ligand-binding domains. Methods in Molecular Biology (Clifton, N.J.). 176: 81-90. PMID 11554340 DOI: 10.1385/1-59259-115-9:81  0.645
2001 Khorasanizadeh S, Rastinejad F. Nuclear-receptor interactions on DNA-response elements. Trends in Biochemical Sciences. 26: 384-90. PMID 11406412 DOI: 10.1016/S0968-0004(01)01800-X  0.648
2001 Rastinejad F. Retinoid X receptor and its partners in the nuclear receptor family. Current Opinion in Structural Biology. 11: 33-8. PMID 11179889 DOI: 10.1016/S0959-440X(00)00165-2  0.629
2000 Wright CS, Li SC, Rastinejad F. Crystal structure of human GM2-activator protein with a novel beta-cup topology. Journal of Molecular Biology. 304: 411-22. PMID 11090283 DOI: 10.1006/Jmbi.2000.4225  0.364
2000 Rastinejad F, Wagner T, Zhao Q, Khorasanizadeh S. Structure of the RXR-RAR DNA-binding complex on the retinoic acid response element DR1. The Embo Journal. 19: 1045-54. PMID 10698945 DOI: 10.1093/Emboj/19.5.1045  0.646
2000 Zhao Q, Chasse SA, Devarakonda S, Sierk ML, Ahvazi B, Rastinejad F. Structural basis of RXR-DNA interactions. Journal of Molecular Biology. 296: 509-20. PMID 10669605 DOI: 10.1006/Jmbi.1999.3457  0.707
1999 Khorasanizadeh S, Rastinejad F. Transcription factors: the right combination for the DNA lock. Current Biology : Cb. 9: R456-8. PMID 10375516 DOI: 10.1016/S0960-9822(99)80281-4  0.555
1998 Zhao Q, Khorasanizadeh S, Miyoshi Y, Lazar MA, Rastinejad F. Structural elements of an orphan nuclear receptor-DNA complex. Molecular Cell. 1: 849-61. PMID 9660968 DOI: 10.1016/S1097-2765(00)80084-2  0.636
1998 Allison TJ, Wood TC, Briercheck DM, Rastinejad F, Richardson JP, Rule GS. Crystal structure of the RNA-binding domain from transcription termination factor rho. Nature Structural Biology. 5: 352-6. PMID 9586995 DOI: 10.1038/Nsb0598-352  0.403
1995 Rastinejad F, Perlmann T, Evans RM, Sigler PB. Structural determinants of nuclear receptor assembly on DNA direct repeats. Nature. 375: 203-11. PMID 7746322 DOI: 10.1038/375203A0  0.543
1993 Rastinejad F, Artz P, Lu P. Origin of the asymmetrical contact between lac repressor and lac operator DNA Journal of Molecular Biology. 233: 389-399. PMID 8411152 DOI: 10.1006/Jmbi.1993.1519  0.449
1993 Rastinejad F, Lu P. Bacteriophage T7 RNA polymerase: 19F-nuclear magnetic resonance observations at 5-Fluorouracil-substituted promoter DNA and RNA transcript Journal of Molecular Biology. 232: 105-122. PMID 8331654 DOI: 10.1006/Jmbi.1993.1373  0.303
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