Iris J. Edwards - Publications

Affiliations: 
Wake Forest University School of Medicine, Winston-Salem, NC, United States 
Area:
Pathology, Biochemistry

26/67 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Gu Z, Wu J, Wang S, Suburu J, Chen H, Thomas MJ, Shi L, Edwards IJ, Berquin IM, Chen YQ. Polyunsaturated fatty acids affect the localization and signaling of PIP3/AKT in prostate cancer cells. Carcinogenesis. 34: 1968-75. PMID 23633519 DOI: 10.1093/Carcin/Bgt147  0.304
2013 Hu Y, Sun H, O'Flaherty JT, Edwards IJ. 15-Lipoxygenase-1-mediated metabolism of docosahexaenoic acid is required for syndecan-1 signaling and apoptosis in prostate cancer cells. Carcinogenesis. 34: 176-82. PMID 23066085 DOI: 10.1093/Carcin/Bgs324  0.31
2012 O'Flaherty JT, Hu Y, Wooten RE, Horita DA, Samuel MP, Thomas MJ, Sun H, Edwards IJ. 15-lipoxygenase metabolites of docosahexaenoic acid inhibit prostate cancer cell proliferation and survival. Plos One. 7: e45480. PMID 23029040 DOI: 10.1371/Journal.Pone.0045480  0.304
2010 Hu Y, Sun H, Owens RT, Gu Z, Wu J, Chen YQ, O'Flaherty JT, Edwards IJ. Syndecan-1-dependent suppression of PDK1/Akt/bad signaling by docosahexaenoic acid induces apoptosis in prostate cancer. Neoplasia (New York, N.Y.). 12: 826-36. PMID 20927321 DOI: 10.1593/Neo.10586  0.324
2008 Edwards IJ, O'Flaherty JT. Omega-3 Fatty Acids and PPARgamma in Cancer. Ppar Research. 2008: 358052. PMID 18769551 DOI: 10.1155/2008/358052  0.329
2008 Berquin IM, Edwards IJ, Chen YQ. Multi-targeted therapy of cancer by omega-3 fatty acids. Cancer Letters. 269: 363-77. PMID 18479809 DOI: 10.1016/J.Canlet.2008.03.044  0.304
2008 Edwards IJ, Sun H, Hu Y, Berquin IM, O'Flaherty JT, Cline JM, Rudel LL, Chen YQ. In vivo and in vitro regulation of syndecan 1 in prostate cells by n-3 polyunsaturated fatty acids. The Journal of Biological Chemistry. 283: 18441-9. PMID 18450755 DOI: 10.1074/Jbc.M802107200  0.336
2008 Sun H, Berquin IM, Owens RT, O'Flaherty JT, Edwards IJ. Peroxisome proliferator-activated receptor gamma-mediated up-regulation of syndecan-1 by n-3 fatty acids promotes apoptosis of human breast cancer cells. Cancer Research. 68: 2912-9. PMID 18413760 DOI: 10.1158/0008-5472.Can-07-2305  0.314
2005 Sun H, Berquin IM, Edwards IJ. Omega-3 polyunsaturated fatty acids regulate syndecan-1 expression in human breast cancer cells. Cancer Research. 65: 4442-7. PMID 15899837 DOI: 10.1158/0008-5472.Can-04-4200  0.355
2004 Edwards IJ, Berquin IM, Sun H, O'flaherty JT, Daniel LW, Thomas MJ, Rudel LL, Wykle RL, Chen YQ. Differential effects of delivery of omega-3 fatty acids to human cancer cells by low-density lipoproteins versus albumin. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 8275-83. PMID 15623603 DOI: 10.1158/1078-0432.Ccr-04-1357  0.332
2004 Edwards IJ, Wagner JD, Vogl-Willis CA, Litwak KN, Cefalu WT. Arterial heparan sulfate is negatively associated with hyperglycemia and atherosclerosis in diabetic monkeys. Cardiovascular Diabetology. 3: 6. PMID 15117408 DOI: 10.1186/1475-2840-3-6  0.622
2004 Vogl-Willis CA, Edwards IJ. High-glucose-induced structural changes in the heparan sulfate proteoglycan, perlecan, of cultured human aortic endothelial cells. Biochimica Et Biophysica Acta. 1672: 36-45. PMID 15056491 DOI: 10.1016/J.Bbagen.2004.02.005  0.654
2004 Vogl-Willis CA, Edwards IJ. High glucose-induced alterations in subendothelial matrix perlecan leads to increased monocyte binding. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 858-63. PMID 15031130 DOI: 10.1161/01.Atv.0000126375.60073.74  0.645
2002 Edwards IJ, Terry JG, Bell-Farrow AD, Cefalu WT. Improved glucose control decreases the interaction of plasma low-density lipoproteins with arterial proteoglycans. Metabolism: Clinical and Experimental. 51: 1223-9. PMID 12370838 DOI: 10.1053/Meta.2002.35177  0.483
2001 Edwards IJ, Rudel LL, Terry JG, Kemnitz JW, Weindruch R, Zaccaro DJ, Cefalu WT. Caloric restriction lowers plasma lipoprotein (a) in male but not female rhesus monkeys. Experimental Gerontology. 36: 1413-8. PMID 11602214 DOI: 10.1016/S0531-5565(01)00107-3  0.303
1999 Cefalu WT, Wagner JD, Bell-Farrow AD, Edwards IJ, Terry JG, Weindruch R, Kemnitz JW. Influence of caloric restriction on the development of atherosclerosis in nonhuman primates: progress to date. Toxicological Sciences : An Official Journal of the Society of Toxicology. 52: 49-55. PMID 10630590 DOI: 10.1093/Toxsci/52.2.49  0.374
1999 Edwards IJ, Wagner JD, Litwak KN, Rudel LL, Cefalu WT. Glycation of plasma low density lipoproteins increases interaction with arterial proteoglycans. Diabetes Research and Clinical Practice. 46: 9-18. PMID 10580610 DOI: 10.1016/S0168-8227(99)00074-1  0.477
1998 Edwards IJ, Rudel LL, Terry JG, Kemnitz JW, Weindruch R, Cefalu WT. Caloric restriction in rhesus monkeys reduces low density lipoprotein interaction with arterial proteoglycans. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 53: B443-8. PMID 9823741 DOI: 10.1093/Gerona/53A.6.B443  0.364
1997 Manning JM, Edwards IJ, Wagner WD, Wagner JD, Adams MR, Parks JS. Effects of contraceptive estrogen and progestin on the atherogenic potential of plasma LDLs in cynomolgus monkeys. Arteriosclerosis, Thrombosis, and Vascular Biology. 17: 1216-23. PMID 9261249 DOI: 10.1161/01.Atv.17.7.1216  0.332
1996 Manning JM, Campos G, Edwards IJ, Wagner WD, Wagner JD, Adams MR, Parks JS. Effects of hormone replacement modalities on low density lipoprotein composition and distribution in ovariectomized cynomolgus monkeys. Atherosclerosis. 121: 217-29. PMID 9125296 DOI: 10.1016/0021-9150(95)05723-4  0.311
1995 Edwards IJ, Xu H, Obunike JC, Goldberg IJ, Wagner WD. Differentiated macrophages synthesize a heparan sulfate proteoglycan and an oversulfated chondroitin sulfate proteoglycan that bind lipoprotein lipase. Arteriosclerosis, Thrombosis, and Vascular Biology. 15: 400-9. PMID 7749850 DOI: 10.1161/01.Atv.15.3.400  0.364
1994 Manning JM, Gebre AK, Edwards IJ, Wagner WD, Rudel LL, Parks JS. Dietary polyunsaturated fat decreases interaction between low density lipoproteins and arterial proteoglycans. Lipids. 29: 635-41. PMID 7815898 DOI: 10.1007/Bf02536098  0.365
1991 Edwards IJ, Gebre AK, Wagner WD, Parks JS. Reduced proteoglycan binding of low density lipoproteins from monkeys (Macaca fascicularis) fed a fish oil versus lard diet. Arteriosclerosis and Thrombosis : a Journal of Vascular Biology / American Heart Association. 11: 1778-85. PMID 1931879 DOI: 10.1161/01.Atv.11.6.1778  0.308
1989 Wagner WD, Edwards IJ, St Clair RW, Barakat H. Low density lipoprotein interaction with artery derived proteoglycan: the influence of LDL particle size and the relationship to atherosclerosis susceptibility. Atherosclerosis. 75: 49-59. PMID 2930613 DOI: 10.1016/0021-9150(89)90206-2  0.369
1987 Sekhara Rao BP, Wagner WD, Hutchins PM, Rowe HA, Edwards IJ. Spontaneous and diet-aggravated atherosclerosis in White Carneau pigeons genetically selected for discordant blood pressure. Atherosclerosis. 65: 29-35. PMID 3606732 DOI: 10.1016/0021-9150(87)90005-0  0.324
1987 Steele RH, Wagner WD, Rowe HA, Edwards IJ. Artery wall derived proteoglycan-plasma lipoprotein interaction: lipoprotein binding properties of extracted proteoglycans. Atherosclerosis. 65: 51-62. PMID 3111491 DOI: 10.1016/0021-9150(87)90007-4  0.384
Low-probability matches (unlikely to be authored by this person)
2012 Edwards IJ. Proteoglycans in prostate cancer. Nature Reviews. Urology. 9: 196-206. PMID 22349653 DOI: 10.1038/Nrurol.2012.19  0.296
2011 Berquin IM, Edwards IJ, Kridel SJ, Chen YQ. Polyunsaturated fatty acid metabolism in prostate cancer. Cancer Metastasis Reviews. 30: 295-309. PMID 22015690 DOI: 10.1007/S10555-011-9299-7  0.295
2000 Cefalu WT, Terry JG, Thomas MJ, Morgan TM, Edwards IJ, Rudel LL, Kemnitz JW, Weindruch R. In vitro oxidation of low-density lipoprotein in two species of nonhuman primates subjected to caloric restriction. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 55: B355-61. PMID 10898249 DOI: 10.1093/Gerona/55.7.B355  0.293
2011 Sun H, Hu Y, Gu Z, Wilson MD, Chen YQ, Rudel LL, Willingham MC, Edwards IJ. Endogenous synthesis of n-3 polyunsaturated fatty acids in Fat-1 mice is associated with increased mammary gland and liver syndecan-1. Plos One. 6: e20502. PMID 21655218 DOI: 10.1371/Journal.Pone.0020502  0.292
2007 Berquin IM, Min Y, Wu R, Wu J, Perry D, Cline JM, Thomas MJ, Thornburg T, Kulik G, Smith A, Edwards IJ, D'Agostino R, Zhang H, Wu H, Kang JX, et al. Modulation of prostate cancer genetic risk by omega-3 and omega-6 fatty acids. The Journal of Clinical Investigation. 117: 1866-75. PMID 17607361 DOI: 10.1172/Jci31494  0.29
1994 Edwards IJ, Xu H, Wright MJ, Wagner WD. Interleukin-1 upregulates decorin production by arterial smooth muscle cells. Arteriosclerosis and Thrombosis : a Journal of Vascular Biology / American Heart Association. 14: 1032-9. PMID 8018657 DOI: 10.1161/01.Atv.14.7.1032  0.289
2006 Chen YQ, Berquin IM, Daniel LW, Edwards IJ, O'Flaherty JT, Thomas MJ, Tooze JA, Wykle B. Omega-3 fatty acids and cancer risk. Jama. 296: 282; author reply 28. PMID 16849660 DOI: 10.1001/Jama.296.3.282-A  0.288
1993 Edwards IJ, Goldberg IJ, Parks JS, Xu H, Wagner WD. Lipoprotein lipase enhances the interaction of low density lipoproteins with artery-derived extracellular matrix proteoglycans. Journal of Lipid Research. 34: 1155-63. PMID 8371063  0.288
2007 Chen YQ, Edwards IJ, Kridel SJ, Thornburg T, Berquin IM. Dietary fat-gene interactions in cancer. Cancer Metastasis Reviews. 26: 535-51. PMID 17849170 DOI: 10.1007/S10555-007-9075-X  0.276
2012 Wang S, Wu J, Suburu J, Gu Z, Cai J, Axanova LS, Cramer SD, Thomas MJ, Perry DL, Edwards IJ, Mucci LA, Sinnott JA, Loda MF, Sui G, Berquin IM, et al. Effect of dietary polyunsaturated fatty acids on castration-resistant Pten-null prostate cancer. Carcinogenesis. 33: 404-12. PMID 22159221 DOI: 10.1093/Carcin/Bgr290  0.266
2009 Hu Y, Sun H, Owens RT, Wu J, Chen YQ, Berquin IM, Perry D, O'Flaherty JT, Edwards IJ. Decorin suppresses prostate tumor growth through inhibition of epidermal growth factor and androgen receptor pathways. Neoplasia (New York, N.Y.). 11: 1042-53. PMID 19794963 DOI: 10.1593/Neo.09760  0.262
1979 Kucera LS, Edwards I. Herpes Simplex Virus Type 2 Functions Expressed During Stimulation of Human Cell DNA Synthesis Journal of Virology. 29: 83-90. PMID 219236 DOI: 10.1128/Jvi.29.1.83-90.1979  0.256
1981 Daniel LW, Waite M, Kucera LS, King L, Edwards I. Phospholipid synthesis in human embryo fibroblasts infected with herpes simplex virus type 2 Lipids. 16: 655-662. PMID 6270493 DOI: 10.1007/Bf02535060  0.255
2013 O'Flaherty JT, Wooten RE, Samuel MP, Thomas MJ, Levine EA, Case LD, Akman SA, Edwards IJ. Fatty acid metabolites in rapidly proliferating breast cancer. Plos One. 8: e63076. PMID 23658799 DOI: 10.1371/Journal.Pone.0063076  0.249
1977 Kucera LS, Gusdon JP, Edwards I, Herbst G. Oncogenic transformation of rat embryo fibroblasts with photoinactivated herpes simplex virus: rapid in vitro cloning of transformed cells. Journal of General Virology. 35: 473-485. PMID 196034 DOI: 10.1099/0022-1317-35-3-473  0.248
1990 Edwards IJ, Wagner WD, Owens RT. Macrophage secretory products selectively stimulate dermatan sulfate proteoglycan production in cultured arterial smooth muscle cells. The American Journal of Pathology. 136: 609-21. PMID 2316626  0.243
1992 Edwards IJ, Wagner WD. Cell surface heparan sulfate proteoglycan and chondroitin sulfate proteoglycan of arterial smooth muscle cells. The American Journal of Pathology. 140: 193-205. PMID 1731524  0.237
1991 Parks JS, Gebre AK, Edwards IJ, Wagner WD. Role of LDL subfraction heterogeneity in the reduced binding of low density lipoproteins to arterial proteoglycans in cynomolgus monkeys fed a fish oil diet. Journal of Lipid Research. 32: 2001-8. PMID 1816328  0.234
1988 Edwards IJ, Wagner WD. Distinct synthetic and structural characteristics of proteoglycans produced by cultured artery smooth muscle cells of atherosclerosis-susceptible pigeons. The Journal of Biological Chemistry. 263: 9612-20. PMID 3133365  0.231
1994 Obunike JC, Edwards IJ, Rumsey SC, Curtiss LK, Wagner WD, Deckelbaum RJ, Goldberg IJ. Cellular differences in lipoprotein lipase-mediated uptake of low density lipoproteins. The Journal of Biological Chemistry. 269: 13129-35. PMID 8175739  0.222
1994 Wagner W, Edwards I, Flory D. Regulation of arterial smooth muscle cell proliferation by cell-surface heparan sulfate proteoglycan Atherosclerosis. 109: 98. DOI: 10.1016/0021-9150(94)93403-7  0.188
2011 Sun H, Hu Y, Gu Z, Owens RT, Chen YQ, Edwards IJ. Omega-3 fatty acids induce apoptosis in human breast cancer cells and mouse mammary tissue through syndecan-1 inhibition of the MEK-Erk pathway. Carcinogenesis. 32: 1518-24. PMID 21771724 DOI: 10.1093/carcin/bgr132  0.183
2013 Edwards IJ, Singh M, Morris S, Osborne L, Le Ruez T, Fuad M, Deuchars SA, Deuchars J. A simple method to fluorescently label pericytes in the CNS and skeletal muscle. Microvascular Research. 89: 164-8. PMID 23764127 DOI: 10.1016/J.Mvr.2013.05.008  0.149
1984 Rowe HA, Edwards IJ, Wagner WD. Reduced content and synthesis of aortic proteoglycans in White Carneau pigeons with naturally occurring atherosclerosis Federation Proceedings. 43: no. 2498.  0.137
2010 Bütikofer P, Greganova E, Liu YC, Edwards IJ, Lehane MJ, Acosta-Serrano A. Lipid remodelling of glycosylphosphatidylinositol (GPI) glycoconjugates in procyclic-form trypanosomes: biosynthesis and processing of GPIs revisited. The Biochemical Journal. 428: 409-18. PMID 20345369 DOI: 10.1042/BJ20100229  0.113
2008 Rivers J, McDonald L, Edwards IJ, Beynon RJ. Asparagine deamidation and the role of higher order protein structure. Journal of Proteome Research. 7: 921-7. PMID 18247555 DOI: 10.1021/pr070425l  0.089
1980 Engelbrecht FM, Edwards IJ, de Beer DP. Metabolic changes in the lungs after ischaemia. South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde. 58: 409-4. PMID 7404167  0.085
2014 Edwards IJ. Highlights in basic autonomic neurosciences: Changes to the autonomic nervous system associated with healthy ageing. Autonomic Neuroscience : Basic & Clinical. 183: 1-3. PMID 24862159 DOI: 10.1016/j.autneu.2014.04.004  0.078
1977 Kucera LS, Leake ES, Edwards IJ, Wright MJ. Biologic and morphologic properties of a new ascites cell line derived from a Lucké renal adenocarcinoma-bearing Rana pipiens. Journal of the Reticuloendothelial Society. 22: 349-62. PMID 200752  0.061
2013 Kirshenbaum GS, Dawson N, Mullins JG, Johnston TH, Drinkhill MJ, Edwards IJ, Fox SH, Pratt JA, Brotchie JM, Roder JC, Clapcote SJ. Alternating hemiplegia of childhood-related neural and behavioural phenotypes in Na+,K+-ATPase α3 missense mutant mice. Plos One. 8: e60141. PMID 23527305 DOI: 10.1371/Journal.Pone.0060141  0.06
2007 Edwards IJ, Dallas ML, Poole SL, Milligan CJ, Yanagawa Y, Szabó G, Erdélyi F, Deuchars SA, Deuchars J. The neurochemically diverse intermedius nucleus of the medulla as a source of excitatory and inhibitory synaptic input to the nucleus tractus solitarii. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 8324-33. PMID 17670979 DOI: 10.1523/Jneurosci.0638-07.2007  0.053
2013 Edwards IJ, Bruce G, Lawrenson C, Howe L, Clapcote SJ, Deuchars SA, Deuchars J. Na+/K+ ATPase α1 and α3 isoforms are differentially expressed in α- and γ-motoneurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 9913-9. PMID 23761886 DOI: 10.1523/Jneurosci.5584-12.2013  0.052
2010 Brooke RE, Corns L, Edwards IJ, Deuchars J. Kv3.3 immunoreactivity in the vestibular nuclear complex of the rat with focus on the medial vestibular nucleus: targeting of Kv3.3 neurones by terminals positive for vesicular glutamate transporter 1. Brain Research. 1345: 45-58. PMID 20471378 DOI: 10.1016/J.Brainres.2010.05.020  0.051
2015 Edwards IJ, Lall VK, Paton JF, Yanagawa Y, Szabo G, Deuchars SA, Deuchars J. Neck muscle afferents influence oromotor and cardiorespiratory brainstem neural circuits. Brain Structure & Function. 220: 1421-36. PMID 24595534 DOI: 10.1007/S00429-014-0734-8  0.047
2015 Corns LF, Atkinson L, Daniel J, Edwards IJ, New L, Deuchars J, Deuchars SA. Cholinergic Enhancement of Cell Proliferation in the Postnatal Neurogenic Niche of the Mammalian Spinal Cord Stem Cells. DOI: 10.1002/stem.2077  0.038
2009 Edwards IJ, Deuchars SA, Deuchars J. The intermedius nucleus of the medulla: a potential site for the integration of cervical information and the generation of autonomic responses. Journal of Chemical Neuroanatomy. 38: 166-75. PMID 19790285 DOI: 10.1016/J.Jchemneu.2009.01.001  0.032
2015 Gotts J, Atkinson L, Edwards IJ, Yanagawa Y, Deuchars SA, Deuchars J. Co-expression of GAD67 and choline acetyltransferase reveals a novel neuronal phenotype in the mouse medulla oblongata Autonomic Neuroscience: Basic and Clinical. DOI: 10.1016/j.autneu.2015.05.003  0.027
1974 Edwards IJ, Jackon WD, Fleming PM. Tipping bucket gauges for measuring run-off from experimental plots Agricultural Meteorology. 13: 189-201. DOI: 10.1016/0002-1571(74)90046-6  0.023
2006 Milligan CJ, Edwards IJ, Deuchars J. HCN1 ion channel immunoreactivity in spinal cord and medulla oblongata. Brain Research. 1081: 79-91. PMID 16503331 DOI: 10.1016/J.Brainres.2006.01.019  0.018
2001 Edwards IJ. The impact of variable hazard rates on in-service reliability Proceedings of the Institution of Mechanical Engineers, Part E: Journal of Process Mechanical Engineering. 215: 233-242. DOI: 10.1243/0954408011530479  0.01
1977 Edwards IJ. The ecological impact of pedestrian traffic on alpine vegetation in kosciusko national park Australian Forestry. 40: 108-120. DOI: 10.1080/00049158.1977.10674159  0.01
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