Daniel L. Hartl, PhD - Publications

Affiliations: 
Organismic and Evolutionary Biology Harvard University, Cambridge, MA, United States 
Area:
evolutionary biology, molecular genetics
Website:
http://www.oeb.harvard.edu/faculty/hartl/lab/index.html

304 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Daniels RF, Schaffner SF, Dieye Y, Dieng G, Hainsworth M, Fall FB, Diouf CN, Ndiop M, Cisse M, Gueye AB, Sarr O, Guinot P, Deme AB, Bei AK, Sy M, ... ... Hartl DL, et al. Genetic evidence for imported malaria and local transmission in Richard Toll, Senegal. Malaria Journal. 19: 276. PMID 32746830 DOI: 10.1186/s12936-020-03346-x  1
2020 Lozovsky ER, Daniels RF, Heffernan GD, Jacobus DP, Hartl DL. Relevance of Higher-Order Epistasis in Drug Resistance. Molecular Biology and Evolution. PMID 32745183 DOI: 10.1093/molbev/msaa196  0.92
2020 Daniels RF, Schaffner SF, Bennett A, Porter TR, Yukich JO, Mulube C, Mambwe B, Mwenda MC, Chishimba S, Bridges DJ, Moonga H, Hamainza B, Chizema Kawesha E, Miller JM, Steketee RW, ... ... Hartl DL, et al. Evidence for Reduced Malaria Parasite Population after Application of Population-Level Antimalarial Drug Strategies in Southern Province, Zambia. The American Journal of Tropical Medicine and Hygiene. PMID 32618255 DOI: 10.4269/ajtmh.19-0666  1
2019 Pham JY, Ogbunugafor CB, Nguyen Ba AN, Hartl DL. Experimental evolution for niche breadth in bacteriophage T4 highlights the importance of structural genes. Microbiologyopen. e968. PMID 31778298 DOI: 10.1002/mbo3.968  1
2019 Golden CD, Borgerson C, Rice BL, Allen LH, Anjaranirina EJG, Barrett CB, Boateng G, Gephart JA, Hampel D, Hartl DL, Knippenberg E, Myers SS, Ralalason DH, Ramihantaniarivo H, Randriamady H, et al. Cohort Description of the Madagascar Health and Environmental Research-Antongil (MAHERY-Antongil) Study in Madagascar. Frontiers in Nutrition. 6: 109. PMID 31428615 DOI: 10.3389/fnut.2019.00109  1
2019 Sharma AI, Demas AR, Hartl DL, Wirth DF. Reply to Velavan et al.: Polymorphisms of in natural populations: Implications for functional significance. Proceedings of the National Academy of Sciences of the United States of America. 116: 12613-12614. PMID 31239364 DOI: 10.1073/pnas.1907920116  1
2019 Rodrigues JV, Ogbunugafor CB, Hartl DL, Shakhnovich EI. Chimeric dihydrofolate reductases display properties of modularity and biophysical diversity. Protein Science : a Publication of the Protein Society. 28: 1359-1367. PMID 31095809 DOI: 10.1002/pro.3646  1
2019 Guerrero RF, Scarpino SV, Rodrigues JV, Hartl DL, Ogbunugafor CB. Proteostasis Environment Shapes Higher-Order Epistasis Operating on Antibiotic Resistance. Genetics. PMID 31015194 DOI: 10.1534/genetics.119.302138  1
2018 Demas AR, Sharma AI, Wong W, Early AM, Redmond S, Bopp S, Neafsey DE, Volkman SK, Hartl DL, Wirth DF. Mutations in actin-binding protein coronin confer reduced artemisinin susceptibility. Proceedings of the National Academy of Sciences of the United States of America. PMID 30420498 DOI: 10.1073/pnas.1812317115  1
2018 Redmond SN, MacInnis BM, Bopp S, Bei AK, Ndiaye D, Hartl DL, Wirth DF, Volkman SK, Neafsey DE. De Novo Mutations Resolve Disease Transmission Pathways in Clonal Malaria. Molecular Biology and Evolution. PMID 29722884 DOI: 10.1093/molbev/msy059  1
2018 Bei AK, Niang M, Deme AB, Daniels RF, Sarr FD, Sokhna C, Talla C, Faye J, Diagne N, Doucoure S, Mboup S, Wirth DF, Tall A, Ndiaye D, Hartl DL, et al. Dramatic Changes in Malaria Population Genetic Complexity in Dielmo and Ndiop, Senegal, Revealed Using Genomic Surveillance. The Journal of Infectious Diseases. PMID 29325146 DOI: 10.1093/infdis/jix580  1
2018 Wong W, Wenger EA, Hartl DL, Wirth DF. Modeling the genetic relatedness of Plasmodium falciparum parasites following meiotic recombination and cotransmission. Plos Computational Biology. 14: e1005923. PMID 29315306 DOI: 10.1371/journal.pcbi.1005923  1
2017 Golden CD, Anjaranirina EJG, Fernald LCH, Hartl DL, Kremen C, Milner DA, Ralalason DH, Ramihantaniarivo H, Randriamady H, Rice BL, Vaitla B, Volkman SK, Vonona MA, Myers SS. Cohort Profile: The Madagascar Health and Environmental Research (MAHERY) study in North-eastern Madagascar. International Journal of Epidemiology. PMID 29040632 DOI: 10.1093/ije/dyx071  1
2017 Wong W, Griggs AD, Daniels RF, Schaffner SF, Ndiaye D, Bei AK, Deme AB, MacInnis B, Volkman SK, Hartl DL, Neafsey DE, Wirth DF. Genetic relatedness analysis reveals the cotransmission of genetically related Plasmodium falciparum parasites in Thiès, Senegal. Genome Medicine. 9: 5. PMID 28118860 DOI: 10.1186/s13073-017-0398-0  1
2016 Volkman SK, Herman J, Lukens AK, Hartl DL. Genome-Wide Association Studies of Drug-Resistance Determinants. Trends in Parasitology. PMID 28179098 DOI: 10.1016/j.pt.2016.10.001  1
2016 Rice BL, Golden CD, Anjaranirina EJ, Botelho CM, Volkman SK, Hartl DL. Genetic evidence that the Makira region in northeastern Madagascar is a hotspot of malaria transmission. Malaria Journal. 15: 596. PMID 27998292 DOI: 10.1186/s12936-016-1644-4  1
2016 Ogbunugafor CB, Hartl DL. A New Take on John Maynard Smith's Concept of Protein Space for Understanding Molecular Evolution. Plos Computational Biology. 12: e1005046. PMID 27736867 DOI: 10.1371/journal.pcbi.1005046  1
2016 Molina-Cruz A, Zilversmit MM, Neafsey DE, Hartl DL, Barillas-Mury C. Mosquito Vectors and the Globalization of Plasmodium falciparum Malaria. Annual Review of Genetics. PMID 27732796 DOI: 10.1146/annurev-genet-120215-035211  1
2016 Sackton TB, Hartl DL. Genotypic Context and Epistasis in Individuals and Populations. Cell. 166: 279-87. PMID 27419868 DOI: 10.1016/j.cell.2016.06.047  0.96
2016 Liénard MA, Araripe LO, Hartl DL. Neighboring genes for DNA-binding proteins rescue male sterility in Drosophila hybrids. Proceedings of the National Academy of Sciences of the United States of America. PMID 27357670 DOI: 10.1073/pnas.1608337113  0.32
2016 Rodrigues JV, Bershtein S, Li A, Lozovsky ER, Hartl DL, Shakhnovich EI. Biophysical principles predict fitness landscapes of drug resistance. Proceedings of the National Academy of Sciences of the United States of America. PMID 26929328 DOI: 10.1073/pnas.1601441113  1
2016 Ogbunugafor CB, Wylie CS, Diakite I, Weinreich DM, Hartl DL. Adaptive Landscape by Environment Interactions Dictate Evolutionary Dynamics in Models of Drug Resistance. Plos Computational Biology. 12: e1004710. PMID 26808374 DOI: 10.1371/journal.pcbi.1004710  1
2016 Ogbunugafor CB, Hartl D. A pivot mutation impedes reverse evolution across an adaptive landscape for drug resistance in Plasmodium vivax Malaria Journal. DOI: 10.1186/s12936-016-1090-3  1
2015 Daniels R, Hamilton EJ, Durfee K, Ndiaye D, Wirth DF, Hartl DL, Volkman SK. Methods to Increase the Sensitivity of High Resolution Melting Single Nucleotide Polymorphism Genotyping in Malaria. Journal of Visualized Experiments : Jove. PMID 26575471 DOI: 10.3791/52839  1
2015 Corbett-Detig R, Jacobs-Palmer E, Hartl D, Hoekstra H. Direct Gamete Sequencing Reveals No Evidence for Segregation Distortion in House Mouse Hybrids. Plos One. 10: e0131933. PMID 26121240 DOI: 10.1371/journal.pone.0131933  1
2015 Ayroles JF, Buchanan SM, O'Leary C, Skutt-Kakaria K, Grenier JK, Clark AG, Hartl DL, de Bivort BL. Behavioral idiosyncrasy reveals genetic control of phenotypic variability. Proceedings of the National Academy of Sciences of the United States of America. 112: 6706-11. PMID 25953335 DOI: 10.1073/pnas.1503830112  1
2015 Daniels RF, Schaffner SF, Wenger EA, Proctor JL, Chang HH, Wong W, Baro N, Ndiaye D, Fall FB, Ndiop M, Ba M, Milner DA, Taylor TE, Neafsey DE, Volkman SK, ... ... Hartl DL, et al. Modeling malaria genomics reveals transmission decline and rebound in Senegal. Proceedings of the National Academy of Sciences of the United States of America. 112: 7067-72. PMID 25941365 DOI: 10.1073/pnas.1505691112  1
2015 Daniels RF, Rice BL, Daniels NM, Volkman SK, Hartl DL. The utility of genomic data for Plasmodium vivax population surveillance. Pathogens and Global Health. 109: 153-61. PMID 25892032 DOI: 10.1179/2047773215Y.0000000014  1
2015 Corbett-Detig RB, Hartl DL, Sackton TB. Natural selection constrains neutral diversity across a wide range of species. Plos Biology. 13: e1002112. PMID 25859758 DOI: 10.1371/journal.pbio.1002112  1
2015 Galinsky K, Valim C, Salmier A, de Thoisy B, Musset L, Legrand E, Faust A, Baniecki ML, Ndiaye D, Daniels RF, Hartl DL, Sabeti PC, Wirth DF, Volkman SK, Neafsey DE. COIL: a methodology for evaluating malarial complexity of infection using likelihood from single nucleotide polymorphism data. Malaria Journal. 14: 4. PMID 25599890 DOI: 10.1186/1475-2875-14-4  1
2015 Obaldia N, Baro NK, Calzada JE, Santamaria AM, Daniels R, Wong W, Chang HH, Hamilton EJ, Arevalo-Herrera M, Herrera S, Wirth DF, Hartl DL, Marti M, Volkman SK. Clonal outbreak of Plasmodium falciparum infection in eastern Panama. The Journal of Infectious Diseases. 211: 1087-96. PMID 25336725 DOI: 10.1093/infdis/jiu575  1
2015 Chang HH, Hartl DL. Recurrent bottlenecks in the malaria life cycle obscure signals of positive selection. Parasitology. 142: S98-S107. PMID 24560397 DOI: 10.1017/S0031182014000067  1
2014 Hartl DL. What can we learn from fitness landscapes? Current Opinion in Microbiology. 21: 51-7. PMID 25444121 DOI: 10.1016/j.mib.2014.08.001  1
2014 Sackton TB, Corbett-Detig RB, Nagaraju J, Vaishna L, Arunkumar KP, Hartl DL. Positive selection drives faster-Z evolution in silkmoths. Evolution; International Journal of Organic Evolution. 68: 2331-42. PMID 24826901 DOI: 10.1111/evo.12449  1
2014 Lukens AK, Ross LS, Heidebrecht R, Javier Gamo F, Lafuente-Monasterio MJ, Booker ML, Hartl DL, Wiegand RC, Wirth DF. Harnessing evolutionary fitness in Plasmodium falciparum for drug discovery and suppressing resistance. Proceedings of the National Academy of Sciences of the United States of America. 111: 799-804. PMID 24381157 DOI: 10.1073/pnas.1320886110  1
2014 Lemos B, Branco AT, Jiang PP, Hartl DL, Meiklejohn CD. Genome-wide gene expression effects of sex chromosome imprinting in Drosophila. G3 (Bethesda, Md.). 4: 1-10. PMID 24318925 DOI: 10.1534/g3.113.008029  1
2014 Meiklejohn CD, Coolon JD, Hartl DL, Wittkopp PJ. The roles of cis- and trans-regulation in the evolution of regulatory incompatibilities and sexually dimorphic gene expression. Genome Research. 24: 84-95. PMID 24043293 DOI: 10.1101/gr.156414.113  1
2013 Chang HH, Moss EL, Park DJ, Ndiaye D, Mboup S, Volkman SK, Sabeti PC, Wirth DF, Neafsey DE, Hartl DL. Malaria life cycle intensifies both natural selection and random genetic drift. Proceedings of the National Academy of Sciences of the United States of America. 110: 20129-34. PMID 24259712 DOI: 10.1073/pnas.1319857110  1
2013 Corbett-Detig RB, Zhou J, Clark AG, Hartl DL, Ayroles JF. Genetic incompatibilities are widespread within species. Nature. 504: 135-7. PMID 24196712 DOI: 10.1038/nature12678  1
2013 Yang S, Li J, Zhang X, Zhang Q, Huang J, Chen JQ, Hartl DL, Tian D. Rapidly evolving R genes in diverse grass species confer resistance to rice blast disease. Proceedings of the National Academy of Sciences of the United States of America. 110: 18572-7. PMID 24145399 DOI: 10.1073/pnas.1318211110  1
2013 Jiang PP, Corbett-Detig RB, Hartl DL, Lozovsky ER. Accessible mutational trajectories for the evolution of pyrimethamine resistance in the malaria parasite Plasmodium vivax. Journal of Molecular Evolution. 77: 81-91. PMID 24071997 DOI: 10.1007/s00239-013-9582-z  1
2013 Nakagawa S, Gisselbrecht SS, Rogers JM, Hartl DL, Bulyk ML. DNA-binding specificity changes in the evolution of forkhead transcription factors. Proceedings of the National Academy of Sciences of the United States of America. 110: 12349-54. PMID 23836653 DOI: 10.1073/pnas.1310430110  1
2013 Branco AT, Hartl DL, Lemos B. Chromatin-associated proteins HP1 and Mod(mdg4) modify Y-linked regulatory variation in the drosophila testis. Genetics. 194: 609-18. PMID 23636736 DOI: 10.1534/genetics.113.150805  0.64
2013 Daniels R, Chang HH, Séne PD, Park DC, Neafsey DE, Schaffner SF, Hamilton EJ, Lukens AK, Van Tyne D, Mboup S, Sabeti PC, Ndiaye D, Wirth DF, Hartl DL, Volkman SK. Genetic surveillance detects both clonal and epidemic transmission of malaria following enhanced intervention in Senegal. Plos One. 8: e60780. PMID 23593309 DOI: 10.1371/journal.pone.0060780  1
2013 Branco AT, Tao Y, Hartl DL, Lemos B. Natural variation of the Y chromosome suppresses sex ratio distortion and modulates testis-specific gene expression in Drosophila simulans. Heredity. 111: 8-15. PMID 23591516 DOI: 10.1038/hdy.2013.5  1
2013 Arnold B, Corbett-Detig RB, Hartl D, Bomblies K. RADseq underestimates diversity and introduces genealogical biases due to nonrandom haplotype sampling. Molecular Ecology. 22: 3179-90. PMID 23551379 DOI: 10.1111/mec.12276  1
2013 Sackton TB, Hartl DL. Meta-analysis reveals that genes regulated by the Y chromosome in Drosophila melanogaster are preferentially localized to repressive chromatin. Genome Biology and Evolution. 5: 255-66. PMID 23315381 DOI: 10.1093/gbe/evt005  1
2013 Chang HH, Daniels RF, Hartl DL. Population Genetics and Parasite Diversity Evolution of Virulence in Eukaryotic Microbes. 1-16. DOI: 10.1002/9781118308165.ch1  1
2012 Corbett-Detig RB, Hartl DL. Population genomics of inversion polymorphisms in Drosophila melanogaster. Plos Genetics. 8: e1003056. PMID 23284285 DOI: 10.1371/journal.pgen.1003056  1
2012 Park DJ, Lukens AK, Neafsey DE, Schaffner SF, Chang HH, Valim C, Ribacke U, Van Tyne D, Galinsky K, Galligan M, Becker JS, Ndiaye D, Mboup S, Wiegand RC, Hartl DL, et al. Sequence-based association and selection scans identify drug resistance loci in the Plasmodium falciparum malaria parasite. Proceedings of the National Academy of Sciences of the United States of America. 109: 13052-7. PMID 22826220 DOI: 10.1073/pnas.1210585109  1
2012 Ponce R, Martinsen L, Vicente LM, Hartl DL. Novel genes from formation to function. International Journal of Evolutionary Biology. 2012: 821645. PMID 22811949 DOI: 10.1155/2012/821645  0.36
2012 Chang HH, Park DJ, Galinsky KJ, Schaffner SF, Ndiaye D, Ndir O, Mboup S, Wiegand RC, Volkman SK, Sabeti PC, Wirth DF, Neafsey DE, Hartl DL. Genomic sequencing of Plasmodium falciparum malaria parasites from Senegal reveals the demographic history of the population. Molecular Biology and Evolution. 29: 3427-39. PMID 22734050 DOI: 10.1093/molbev/mss161  1
2012 Zhou J, Sackton TB, Martinsen L, Lemos B, Eickbush TH, Hartl DL. Y chromosome mediates ribosomal DNA silencing and modulates the chromatin state in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 109: 9941-6. PMID 22665801 DOI: 10.1073/pnas.1207367109  1
2012 Yeh SD, Do T, Chan C, Cordova A, Carranza F, Yamamoto EA, Abbassi M, Gandasetiawan KA, Librado P, Damia E, Dimitri P, Rozas J, Hartl DL, Roote J, Ranz JM. Functional evidence that a recently evolved Drosophila sperm-specific gene boosts sperm competition. Proceedings of the National Academy of Sciences of the United States of America. 109: 2043-8. PMID 22308475 DOI: 10.1073/pnas.1121327109  1
2012 Volkman SK, Ndiaye D, Diakite M, Koita OA, Nwakanma D, Daniels RF, Park DJ, Neafsey DE, Muskavitch MA, Krogstad DJ, Sabeti PC, Hartl DL, Wirth DF. Application of genomics to field investigations of malaria by the international centers of excellence for malaria research. Acta Tropica. 121: 324-32. PMID 22182668 DOI: 10.1016/j.actatropica.2011.12.002  1
2012 Toprak E, Veres A, Michel JB, Chait R, Hartl DL, Kishony R. Evolutionary paths to antibiotic resistance under dynamically sustained drug selection. Nature Genetics. 44: 101-5. PMID 22179135 DOI: 10.1038/ng.1034  1
2012 Rogers RL, Hartl DL. Chimeric genes as a source of rapid evolution in Drosophila melanogaster. Molecular Biology and Evolution. 29: 517-29. PMID 21771717 DOI: 10.1093/molbev/msr184  1
2011 Carneiro MO, Taubes CH, Hartl DL. Model transcriptional networks with continuously varying expression levels. Bmc Evolutionary Biology. 11: 363. PMID 22182343 DOI: 10.1186/1471-2148-11-363  1
2011 Hartl DL. James F. Crow and the art of teaching and mentoring. Genetics. 189: 1129-33. PMID 22174181 DOI: 10.1534/genetics.111.135160  1
2011 Zhou J, Lemos B, Dopman EB, Hartl DL. Copy-number variation: the balance between gene dosage and expression in Drosophila melanogaster. Genome Biology and Evolution. 3: 1014-24. PMID 21979154 DOI: 10.1093/gbe/evr023  1
2011 Sackton TB, Montenegro H, Hartl DL, Lemos B. Interspecific Y chromosome introgressions disrupt testis-specific gene expression and male reproductive phenotypes in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 108: 17046-51. PMID 21969588 DOI: 10.1073/pnas.1114690108  1
2011 Costanzo MS, Hartl DL. The evolutionary landscape of antifolate resistance in Plasmodium falciparum. Journal of Genetics. 90: 187-90. PMID 21869466 DOI: 10.1007/s12041-011-0072-z  1
2011 Costanzo MS, Brown KM, Hartl DL. Fitness trade-offs in the evolution of dihydrofolate reductase and drug resistance in Plasmodium falciparum. Plos One. 6: e19636. PMID 21625425 DOI: 10.1371/journal.pone.0019636  1
2011 Paredes S, Branco AT, Hartl DL, Maggert KA, Lemos B. Ribosomal DNA deletions modulate genome-wide gene expression: "rDNA-sensitive" genes and natural variation. Plos Genetics. 7: e1001376. PMID 21533076 DOI: 10.1371/journal.pgen.1001376  1
2011 Van Tyne D, Park DJ, Schaffner SF, Neafsey DE, Angelino E, Cortese JF, Barnes KG, Rosen DM, Lukens AK, Daniels RF, Milner DA, Johnson CA, Shlyakhter I, Grossman SR, Becker JS, ... ... Hartl DL, et al. Identification and functional validation of the novel antimalarial resistance locus PF10_0355 in Plasmodium falciparum. Plos Genetics. 7: e1001383. PMID 21533027 DOI: 10.1371/journal.pgen.1001383  1
2011 Geiler-Samerotte KA, Dion MF, Budnik BA, Wang SM, Hartl DL, Drummond DA. Misfolded proteins impose a dosage-dependent fitness cost and trigger a cytosolic unfolded protein response in yeast. Proceedings of the National Academy of Sciences of the United States of America. 108: 680-5. PMID 21187411 DOI: 10.1073/pnas.1017570108  1
2010 Araripe LO, Montenegro H, Lemos B, Hartl DL. Fine-scale genetic mapping of a hybrid sterility factor between Drosophila simulans and D. mauritiana: the varied and elusive functions of "speciation genes". Bmc Evolutionary Biology. 10: 385. PMID 21144061 DOI: 10.1186/1471-2148-10-385  1
2010 Lemos B, Branco AT, Hartl DL. Epigenetic effects of polymorphic Y chromosomes modulate chromatin components, immune response, and sexual conflict. Proceedings of the National Academy of Sciences of the United States of America. 107: 15826-31. PMID 20798037 DOI: 10.1073/pnas.1010383107  1
2010 Brown KM, Costanzo MS, Xu W, Roy S, Lozovsky ER, Hartl DL. Compensatory mutations restore fitness during the evolution of dihydrofolate reductase. Molecular Biology and Evolution. 27: 2682-90. PMID 20576759 DOI: 10.1093/molbev/msq160  1
2010 Jiang PP, Hartl DL, Lemos B. Y not a dead end: epistatic interactions between Y-linked regulatory polymorphisms and genetic background affect global gene expression in Drosophila melanogaster. Genetics. 186: 109-18. PMID 20551438 DOI: 10.1534/genetics.110.118109  1
2010 Rogers RL, Bedford T, Lyons AM, Hartl DL. Adaptive impact of the chimeric gene Quetzalcoatl in Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America. 107: 10943-8. PMID 20534482 DOI: 10.1073/pnas.1006503107  1
2010 Zilversmit MM, Volkman SK, DePristo MA, Wirth DF, Awadalla P, Hartl DL. Low-complexity regions in Plasmodium falciparum: missing links in the evolution of an extreme genome. Molecular Biology and Evolution. 27: 2198-209. PMID 20427419 DOI: 10.1093/molbev/msq108  1
2010 Fontanillas P, Landry CR, Wittkopp PJ, Russ C, Gruber JD, Nusbaum C, Hartl DL. Key considerations for measuring allelic expression on a genomic scale using high-throughput sequencing. Molecular Ecology. 19: 212-27. PMID 20331781 DOI: 10.1111/j.1365-294X.2010.04472.x  1
2010 Gunawardena S, Karunaweera ND, Ferreira MU, Phone-Kyaw M, Pollack RJ, Alifrangis M, Rajakaruna RS, Konradsen F, Amerasinghe PH, Schousboe ML, Galappaththy GN, Abeyasinghe RR, Hartl DL, Wirth DF. Geographic structure of Plasmodium vivax: microsatellite analysis of parasite populations from Sri Lanka, Myanmar, and Ethiopia. The American Journal of Tropical Medicine and Hygiene. 82: 235-42. PMID 20133999 DOI: 10.4269/ajtmh.2010.09-0588  1
2010 Kingan SB, Garrigan D, Hartl DL. Recurrent selection on the Winters sex-ratio genes in Drosophila simulans. Genetics. 184: 253-65. PMID 19897749 DOI: 10.1534/genetics.109.109587  1
2010 Carneiro M, Hartl DL. Colloquium papers: Adaptive landscapes and protein evolution. Proceedings of the National Academy of Sciences of the United States of America. 107: 1747-51. PMID 19805125 DOI: 10.1073/pnas.0906192106  1
2009 Sackton TB, Kulathinal RJ, Bergman CM, Quinlan AR, Dopman EB, Carneiro M, Marth GT, Hartl DL, Clark AG. Population genomic inferences from sparse high-throughput sequencing of two populations of Drosophila melanogaster. Genome Biology and Evolution. 1: 449-65. PMID 20333214 DOI: 10.1093/gbe/evp048  1
2009 Brown KM, Depristo MA, Weinreich DM, Hartl DL. Temporal constraints on the incorporation of regulatory mutants in evolutionary pathways. Molecular Biology and Evolution. 26: 2455-62. PMID 19602543 DOI: 10.1093/molbev/msp151  1
2009 Lozovsky ER, Chookajorn T, Brown KM, Imwong M, Shaw PJ, Kamchonwongpaisan S, Neafsey DE, Weinreich DM, Hartl DL. Stepwise acquisition of pyrimethamine resistance in the malaria parasite. Proceedings of the National Academy of Sciences of the United States of America. 106: 12025-30. PMID 19587242 DOI: 10.1073/pnas.0905922106  1
2009 Mayer DC, Cofie J, Jiang L, Hartl DL, Tracy E, Kabat J, Mendoza LH, Miller LH. Glycophorin B is the erythrocyte receptor of Plasmodium falciparum erythrocyte-binding ligand, EBL-1. Proceedings of the National Academy of Sciences of the United States of America. 106: 5348-52. PMID 19279206 DOI: 10.1073/pnas.0900878106  1
2009 Bedford T, Hartl DL. Optimization of gene expression by natural selection. Proceedings of the National Academy of Sciences of the United States of America. 106: 1133-8. PMID 19139403 DOI: 10.1073/pnas.0812009106  1
2009 Rogers RL, Bedford T, Hartl DL. Formation and longevity of chimeric and duplicate genes in Drosophila melanogaster. Genetics. 181: 313-22. PMID 19015547 DOI: 10.1534/genetics.108.091538  0.4
2008 Neafsey DE, Schaffner SF, Volkman SK, Park D, Montgomery P, Milner DA, Lukens A, Rosen D, Daniels R, Houde N, Cortese JF, Tyndall E, Gates C, Stange-Thomann N, Sarr O, ... ... Hartl DL, et al. Genome-wide SNP genotyping highlights the role of natural selection in Plasmodium falciparum population divergence. Genome Biology. 9: R171. PMID 19077304 DOI: 10.1186/gb-2008-9-12-r171  1
2008 Lemos B, Araripe LO, Fontanillas P, Hartl DL. Dominance and the evolutionary accumulation of cis- and trans-effects on gene expression. Proceedings of the National Academy of Sciences of the United States of America. 105: 14471-6. PMID 18791071 DOI: 10.1073/pnas.0805160105  1
2008 Hegreness M, Shoresh N, Damian D, Hartl D, Kishony R. Accelerated evolution of resistance in multidrug environments. Proceedings of the National Academy of Sciences of the United States of America. 105: 13977-81. PMID 18779569 DOI: 10.1073/pnas.0805965105  1
2008 Lynch M, Sung W, Morris K, Coffey N, Landry CR, Dopman EB, Dickinson WJ, Okamoto K, Kulkarni S, Hartl DL, Thomas WK. A genome-wide view of the spectrum of spontaneous mutations in yeast. Proceedings of the National Academy of Sciences of the United States of America. 105: 9272-7. PMID 18583475 DOI: 10.1073/pnas.0803466105  1
2008 Bedford T, Wapinski I, Hartl DL. Overdispersion of the molecular clock varies between yeast, Drosophila and mammals. Genetics. 179: 977-84. PMID 18505862 DOI: 10.1534/genetics.108.089185  1
2008 Bedford T, Hartl DL. Overdispersion of the molecular clock: temporal variation of gene-specific substitution rates in Drosophila. Molecular Biology and Evolution. 25: 1631-8. PMID 18480070 DOI: 10.1093/molbev/msn112  1
2008 Baines JF, Sawyer SA, Hartl DL, Parsch J. Effects of X-linkage and sex-biased gene expression on the rate of adaptive protein evolution in Drosophila. Molecular Biology and Evolution. 25: 1639-50. PMID 18477586 DOI: 10.1093/molbev/msn111  1
2008 Brown KM, Landry CR, Hartl DL, Cavalieri D. Cascading transcriptional effects of a naturally occurring frameshift mutation in Saccharomyces cerevisiae. Molecular Ecology. 17: 2985-97. PMID 18422925 DOI: 10.1111/j.1365-294X.2008.03765.x  1
2008 Amodu OK, Hartl DL, Roy SW. Patterns of polymorphism in genomic regions flanking three highly polymorphic surface antigens in Plasmodium falciparum. Molecular and Biochemical Parasitology. 159: 1-6. PMID 18291540 DOI: 10.1016/j.molbiopara.2007.12.004  1
2008 Karunaweera ND, Ferreira MU, Munasinghe A, Barnwell JW, Collins WE, King CL, Kawamoto F, Hartl DL, Wirth DF. Extensive microsatellite diversity in the human malaria parasite Plasmodium vivax. Gene. 410: 105-12. PMID 18226474 DOI: 10.1016/j.gene.2007.11.022  1
2008 Lemos B, Araripe LO, Hartl DL. Polymorphic Y chromosomes harbor cryptic variation with manifold functional consequences. Science (New York, N.Y.). 319: 91-3. PMID 18174442 DOI: 10.1126/science.1148861  1
2008 Roy SW, Ferreira MU, Hartl DL. Evolution of allelic dimorphism in malarial surface antigens. Heredity. 100: 103-10. PMID 17021615 DOI: 10.1038/sj.hdy.6800887  1
2007 Fontanillas P, Hartl DL, Reuter M. Genome organization and gene expression shape the transposable element distribution in the Drosophila melanogaster euchromatin. Plos Genetics. 3: e210. PMID 18081425 DOI: 10.1371/journal.pgen.0030210  1
2007 Dopman EB, Hartl DL. A portrait of copy-number polymorphism in Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America. 104: 19920-5. PMID 18056801 DOI: 10.1073/pnas.0709888104  1
2007 Tao Y, Araripe L, Kingan SB, Ke Y, Xiao H, Hartl DL. A sex-ratio meiotic drive system in Drosophila simulans. II: an X-linked distorter. Plos Biology. 5: e293. PMID 17988173 DOI: 10.1371/journal.pbio.0050293  1
2007 Tao Y, Masly JP, Araripe L, Ke Y, Hartl DL. A sex-ratio meiotic drive system in Drosophila simulans. I: an autosomal suppressor. Plos Biology. 5: e292. PMID 17988172 DOI: 10.1371/journal.pbio.0050292  1
2007 Chookajorn T, Costanzo MS, Hartl DL, Deitsch KW. Malaria: a peek at the var variorum. Trends in Parasitology. 23: 563-5. PMID 17977793 DOI: 10.1016/j.pt.2007.08.022  1
2007 Landry CR, Hartl DL, Ranz JM. Genome clashes in hybrids: insights from gene expression. Heredity. 99: 483-93. PMID 17687247 DOI: 10.1038/sj.hdy.6801045  1
2007 DePristo MA, Hartl DL, Weinreich DM. Mutational reversions during adaptive protein evolution. Molecular Biology and Evolution. 24: 1608-10. PMID 17556755 DOI: 10.1093/molbev/msm118  1
2007 Landry CR, Lemos B, Rifkin SA, Dickinson WJ, Hartl DL. Genetic properties influencing the evolvability of gene expression. Science (New York, N.Y.). 317: 118-21. PMID 17525304 DOI: 10.1126/science.1140247  0.84
2007 Sawyer SA, Parsch J, Zhang Z, Hartl DL. Prevalence of positive selection among nearly neutral amino acid replacements in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 104: 6504-10. PMID 17409186 DOI: 10.1073/pnas.0701572104  1
2007 Landry CR, Castillo-Davis CI, Ogura A, Liu JS, Hartl DL. Systems-level analysis and evolution of the phototransduction network in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 104: 3283-8. PMID 17360639 DOI: 10.1073/pnas.0611402104  1
2007 Ferreira MU, Karunaweera ND, da Silva-Nunes M, da Silva NS, Wirth DF, Hartl DL. Population structure and transmission dynamics of Plasmodium vivax in rural Amazonia. The Journal of Infectious Diseases. 195: 1218-26. PMID 17357061 DOI: 10.1086/512685  1
2007 Gunasekera AM, Wickramarachchi T, Neafsey DE, Ganguli I, Perera L, Premaratne PH, Hartl D, Handunnetti SM, Udagama-Randeniya PV, Wirth DF. Genetic diversity and selection at the Plasmodium vivax apical membrane antigen-1 (PvAMA-1) locus in a Sri Lankan population. Molecular Biology and Evolution. 24: 939-47. PMID 17244598 DOI: 10.1093/molbev/msm013  1
2007 Chookajorn T, Dzikowski R, Frank M, Li F, Jiwani AZ, Hartl DL, Deitsch KW. Epigenetic memory at malaria virulence genes. Proceedings of the National Academy of Sciences of the United States of America. 104: 899-902. PMID 17209011 DOI: 10.1073/pnas.0609084103  1
2007 Volkman SK, Sabeti PC, DeCaprio D, Neafsey DE, Schaffner SF, Milner DA, Daily JP, Sarr O, Ndiaye D, Ndir O, Mboup S, Duraisingh MT, Lukens A, Derr A, Stange-Thomann N, ... ... Hartl DL, et al. A genome-wide map of diversity in Plasmodium falciparum. Nature Genetics. 39: 113-9. PMID 17159979 DOI: 10.1038/ng1930  1
2007 Volkman SK, Lozovsky E, Barry AE, Bedford T, Bethke L, Myrick A, Day KP, Hartl DL, Wirth DF, Sawyer SA. Genomic heterogeneity in the density of noncoding single-nucleotide and microsatellite polymorphisms in Plasmodium falciparum. Gene. 387: 1-6. PMID 17005334 DOI: 10.1016/j.gene.2006.07.026  1
2007 Ferreira MU, Hartl DL. Plasmodium falciparum: worldwide sequence diversity and evolution of the malaria vaccine candidate merozoite surface protein-2 (MSP-2). Experimental Parasitology. 115: 32-40. PMID 16797008 DOI: 10.1016/j.exppara.2006.05.003  1
2007 Karunaweera ND, Ferreira MU, Hartl DL, Wirth DF. Fourteen polymorphic microsatellite DNA markers for the human malaria parasite Plasmodium vivax Molecular Ecology Notes. 7: 172-175. DOI: 10.1111/j.1471-8286.2006.01534.x  1
2007 Karunaweera ND, Ferreira MU, Hartl DL, Wirth DF. Fourteen polymorphic microsatellite DNA markers for the human malaria parasite Plasmodium vivax Molecular Ecology Notes. 7: 172-175. DOI: 10.1111/j.1471-8286.2006.01534.x  1
2006 Bethke LL, Zilversmit M, Nielsen K, Daily J, Volkman SK, Ndiaye D, Lozovsky ER, Hartl DL, Wirth DF. Duplication, gene conversion, and genetic diversity in the species-specific acyl-CoA synthetase gene family of Plasmodium falciparum. Molecular and Biochemical Parasitology. 150: 10-24. PMID 16860410 DOI: 10.1016/j.molbiopara.2006.06.004  1
2006 DePristo MA, Zilversmit MM, Hartl DL. On the abundance, amino acid composition, and evolutionary dynamics of low-complexity regions in proteins. Gene. 378: 19-30. PMID 16806741 DOI: 10.1016/j.gene.2006.03.023  1
2006 Barry AE, Leliwa-Sytek A, Man K, Kasper JM, Hartl DL, Day KP. Variable SNP density in aspartyl-protease genes of the malaria parasite Plasmodium falciparum. Gene. 376: 163-73. PMID 16784823 DOI: 10.1016/j.gene.2006.02.029  1
2006 Ponce R, Hartl DL. The evolution of the novel Sdic gene cluster in Drosophila melanogaster. Gene. 376: 174-83. PMID 16765537 DOI: 10.1016/j.gene.2006.02.011  1
2006 Roy SW, Hartl DL. Very little intron loss/gain in Plasmodium: intron loss/gain mutation rates and intron number. Genome Research. 16: 750-6. PMID 16702411 DOI: 10.1101/gr.4845406  1
2006 Chookajorn T, Hartl DL. Position-specific polymorphism of Plasmodium falciparum Stuttering motif in a PHISTc PFI1780w. Experimental Parasitology. 114: 126-8. PMID 16674945 DOI: 10.1016/j.exppara.2006.02.019  1
2006 Weinreich DM, Delaney NF, Depristo MA, Hartl DL. Darwinian evolution can follow only very few mutational paths to fitter proteins. Science (New York, N.Y.). 312: 111-4. PMID 16601193 DOI: 10.1126/science.1123539  1
2006 Hegreness M, Shoresh N, Hartl D, Kishony R. An equivalence principle for the incorporation of favorable mutations in asexual populations. Science (New York, N.Y.). 311: 1615-7. PMID 16543462 DOI: 10.1126/science.1122469  1
2006 Landry CR, Townsend JP, Hartl DL, Cavalieri D. Ecological and evolutionary genomics of Saccharomyces cerevisiae. Molecular Ecology. 15: 575-91. PMID 16499686 DOI: 10.1111/j.1365-294X.2006.02778.x  1
2006 Landry CR, Oh J, Hartl DL, Cavalieri D. Genome-wide scan reveals that genetic variation for transcriptional plasticity in yeast is biased towards multi-copy and dispensable genes. Gene. 366: 343-51. PMID 16427747 DOI: 10.1016/j.gene.2005.10.042  1
2005 Blumenstiel JP, Hartl DL. Evidence for maternally transmitted small interfering RNA in the repression of transposition in Drosophila virilis. Proceedings of the National Academy of Sciences of the United States of America. 102: 15965-70. PMID 16247000 DOI: 10.1073/pnas.0508192102  1
2005 Landry CR, Wittkopp PJ, Taubes CH, Ranz JM, Clark AG, Hartl DL. Compensatory cis-trans evolution and the dysregulation of gene expression in interspecific hybrids of Drosophila. Genetics. 171: 1813-22. PMID 16143608 DOI: 10.1534/genetics.105.047449  1
2005 DePristo MA, Weinreich DM, Hartl DL. Missense meanderings in sequence space: a biophysical view of protein evolution. Nature Reviews. Genetics. 6: 678-87. PMID 16074985 DOI: 10.1038/nrg1672  1
2005 Neafsey DE, Hartl DL, Berriman M. Evolution of noncoding and silent coding sites in the Plasmodium falciparum and Plasmodium reichenowi genomes. Molecular Biology and Evolution. 22: 1621-6. PMID 15858207 DOI: 10.1093/molbev/msi154  1
2005 Neafsey DE, Hartl DL. Convergent loss of an anciently duplicated, functionally divergent RH2 opsin gene in the fugu and Tetraodon pufferfish lineages. Gene. 350: 161-71. PMID 15820147 DOI: 10.1016/j.gene.2005.02.011  1
2005 Lemos B, Meiklejohn CD, Cáceres M, Hartl DL. Rates of divergence in gene expression profiles of primates, mice, and flies: stabilizing selection and variability among functional categories. Evolution; International Journal of Organic Evolution. 59: 126-37. PMID 15792233  1
2005 Lemos B, Bettencourt BR, Meiklejohn CD, Hartl DL. Evolution of proteins and gene expression levels are coupled in Drosophila and are independently associated with mRNA abundance, protein length, and number of protein-protein interactions. Molecular Biology and Evolution. 22: 1345-54. PMID 15746013 DOI: 10.1093/molbev/msi122  1
2005 Kulathinal RJ, Hartl DL. The latest buzz in comparative genomics. Genome Biology. 6: 201. PMID 15642105 DOI: 10.1186/gb-2005-6-1-201  1
2004 Kulathinal RJ, Bettencourt BR, Hartl DL. Compensated deleterious mutations in insect genomes. Science (New York, N.Y.). 306: 1553-4. PMID 15498973 DOI: 10.1126/science.1100522  1
2004 Meiklejohn CD, Kim Y, Hartl DL, Parsch J. Identification of a locus under complex positive selection in Drosophila simulans by haplotype mapping and composite-likelihood estimation. Genetics. 168: 265-79. PMID 15454542 DOI: 10.1534/genetics.103.025494  1
2004 Lemos B, Meiklejohn CD, Hartl DL. Regulatory evolution across the protein interaction network. Nature Genetics. 36: 1059-60. PMID 15378060 DOI: 10.1038/ng1427  1
2004 Neafsey DE, Blumenstiel JP, Hartl DL. Different regulatory mechanisms underlie similar transposable element profiles in pufferfish and fruitflies. Molecular Biology and Evolution. 21: 2310-8. PMID 15342795 DOI: 10.1093/molbev/msh243  1
2004 Castillo-Davis CI, Hartl DL, Achaz G. cis-Regulatory and protein evolution in orthologous and duplicate genes. Genome Research. 14: 1530-6. PMID 15256508 DOI: 10.1101/gr.2662504  1
2004 Castillo-Davis CI, Kondrashov FA, Hartl DL, Kulathinal RJ. The functional genomic distribution of protein divergence in two animal phyla: coevolution, genomic conflict, and constraint. Genome Research. 14: 802-11. PMID 15123580 DOI: 10.1101/gr.2195604  1
2004 Castillo-Davis CI, Bedford TB, Hartl DL. Accelerated rates of intron gain/loss and protein evolution in duplicate genes in human and mouse malaria parasites. Molecular Biology and Evolution. 21: 1422-7. PMID 15084679 DOI: 10.1093/molbev/msh143  1
2004 Hartl DL. The origin of malaria: mixed messages from genetic diversity. Nature Reviews. Microbiology. 2: 15-22. PMID 15035005 DOI: 10.1038/nrmicro795  1
2004 Ranz JM, Namgyal K, Gibson G, Hartl DL. Anomalies in the expression profile of interspecific hybrids of Drosophila melanogaster and Drosophila simulans. Genome Research. 14: 373-9. PMID 14962989 DOI: 10.1101/gr.2019804  1
2003 Cavalieri D, McGovern PE, Hartl DL, Mortimer R, Polsinelli M. Evidence for S. cerevisiae fermentation in ancient wine. Journal of Molecular Evolution. 57: S226-32. PMID 15008419 DOI: 10.1007/s00239-003-0031-2  1
2003 Sawyer SA, Kulathinal RJ, Bustamante CD, Hartl DL. Bayesian analysis suggests that most amino acid replacements in Drosophila are driven by positive selection. Journal of Molecular Evolution. 57: S154-64. PMID 15008412 DOI: 10.1007/s00239-003-0022-3  1
2003 Tao Y, Hartl DL. Genetic dissection of hybrid incompatibilities between Drosophila simulans and D. mauritiana. III. Heterogeneous accumulation of hybrid incompatibilities, degree of dominance, and implications for Haldane's rule. Evolution; International Journal of Organic Evolution. 57: 2580-98. PMID 14686533  1
2003 Castillo-Davis CI, Hartl DL. Conservation, relocation and duplication in genome evolution. Trends in Genetics : Tig. 19: 593-7. PMID 14585607 DOI: 10.1016/j.tig.2003.09.009  1
2003 Barry AE, Leliwa A, Choi M, Nielsen KM, Hartl DL, Day KP. DNA sequence artifacts and the estimation of time to the most recent common ancestor (TMRCA) of Plasmodium falciparum. Molecular and Biochemical Parasitology. 130: 143-7. PMID 12946852 DOI: 10.1016/S0166-6851(03)00164-6  1
2003 Tao Y, Zeng ZB, Li J, Hartl DL, Laurie CC. Genetic dissection of hybrid incompatibilities between Drosophila simulans and D. mauritiana. II. Mapping hybrid male sterility loci on the third chromosome. Genetics. 164: 1399-418. PMID 12930748  1
2003 Tao Y, Chen S, Hartl DL, Laurie CC. Genetic dissection of hybrid incompatibilities between Drosophila simulans and D. mauritiana. I. Differential accumulation of hybrid male sterility effects on the X and autosomes. Genetics. 164: 1383-97. PMID 12930747  1
2003 Meiklejohn CD, Parsch J, Ranz JM, Hartl DL. Rapid evolution of male-biased gene expression in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 100: 9894-9. PMID 12907700 DOI: 10.1073/pnas.1630690100  1
2003 Ranz JM, Ponce AR, Hartl DL, Nurminsky D. Origin and evolution of a new gene expressed in the Drosophila sperm axoneme. Genetica. 118: 233-44. PMID 12868612 DOI: 10.1023/A:1024186516554  1
2003 Ranz JM, Castillo-Davis CI, Meiklejohn CD, Hartl DL. Sex-dependent gene expression and evolution of the Drosophila transcriptome. Science (New York, N.Y.). 300: 1742-5. PMID 12805547 DOI: 10.1126/science.1085881  1
2003 Townsend JP, Nielsen KM, Fisher DS, Hartl DL. Horizontal acquisition of divergent chromosomal DNA in bacteria: effects of mutator phenotypes. Genetics. 164: 13-21. PMID 12750317  1
2003 Castillo-Davis CI, Hartl DL. GeneMerge--post-genomic analysis, data mining, and hypothesis testing. Bioinformatics (Oxford, England). 19: 891-2. PMID 12724301 DOI: 10.1093/bioinformatics/btg114  1
2003 Townsend JP, Cavalieri D, Hartl DL. Population genetic variation in genome-wide gene expression. Molecular Biology and Evolution. 20: 955-63. PMID 12716989 DOI: 10.1093/molbev/msg106  1
2003 Nielsen KM, Kasper J, Choi M, Bedford T, Kristiansen K, Wirth DF, Volkman SK, Lozovsky ER, Hartl DL. Gene conversion as a source of nucleotide diversity in Plasmodium falciparum. Molecular Biology and Evolution. 20: 726-34. PMID 12679555 DOI: 10.1093/molbev/msg076  1
2003 Bustamante CD, Nielsen R, Hartl DL. Maximum likelihood and Bayesian methods for estimating the distribution of selective effects among classes of mutations using DNA polymorphism data. Theoretical Population Biology. 63: 91-103. PMID 12615493 DOI: 10.1016/S0040-5809(02)00050-3  1
2003 Winzeler EA, Castillo-Davis CI, Oshiro G, Liang D, Richards DR, Zhou Y, Hartl DL. Genetic diversity in yeast assessed with whole-genome oligonucleotide arrays. Genetics. 163: 79-89. PMID 12586698  1
2003 Volkman SK, Hartl DL. Parasitology. A game of cat and mouth. Science (New York, N.Y.). 299: 353-4. PMID 12532003 DOI: 10.1126/science.1081278  1
2002 Townsend JP, Hartl DL. Bayesian analysis of gene expression levels: statistical quantification of relative mRNA level across multiple strains or treatments. Genome Biology. 3: RESEARCH0071. PMID 12537560  1
2002 Blumenstiel JP, Hartl DL, Lozovsky ER. Patterns of insertion and deletion in contrasting chromatin domains. Molecular Biology and Evolution. 19: 2211-25. PMID 12446812  1
2002 Volkman SK, Hartl DL, Wirth DF, Nielsen KM, Choi M, Batalov S, Zhou Y, Plouffe D, Le Roch KG, Abagyan R, Winzeler EA. Excess polymorphisms in genes for membrane proteins in Plasmodium falciparum. Science (New York, N.Y.). 298: 216-8. PMID 12364807 DOI: 10.1126/science.1075642  1
2002 Castillo-Davis CI, Mekhedov SL, Hartl DL, Koonin EV, Kondrashov FA. Selection for short introns in highly expressed genes. Nature Genetics. 31: 415-8. PMID 12134150 DOI: 10.1038/ng940  1
2002 Grosu P, Townsend JP, Hartl DL, Cavalieri D. Pathway Processor: a tool for integrating whole-genome expression results into metabolic networks. Genome Research. 12: 1121-6. PMID 12097350 DOI: 10.1101/gr.226602  1
2002 Hartl DL, Volkman SK, Nielsen KM, Barry AE, Day KP, Wirth DF, Winzeler EA. The paradoxical population genetics of Plasmodium falciparum. Trends in Parasitology. 18: 266-72. PMID 12036741 DOI: 10.1016/S1471-4922(02)02268-7  1
2002 Castillo-Davis CI, Hartl DL. Genome evolution and developmental constraint in Caenorhabditis elegans. Molecular Biology and Evolution. 19: 728-35. PMID 11961106  1
2002 Bustamante CD, Nielsen R, Sawyer SA, Olsen KM, Purugganan MD, Hartl DL. The cost of inbreeding in Arabidopsis. Nature. 416: 531-4. PMID 11932744 DOI: 10.1038/416531a  1
2002 Lozovsky ER, Nurminsky D, Wimmer EA, Hartl DL. Unexpected stability of mariner transgenes in Drosophila. Genetics. 160: 527-35. PMID 11861559  1
2002 Lohe AR, Hartl DL. Efficient mobilization of mariner in vivo requires multiple internal sequences. Genetics. 160: 519-26. PMID 11861558  1
2002 Bustamante CD, Nielsen R, Hartl DL. A maximum likelihood method for analyzing pseudogene evolution: implications for silent site evolution in humans and rodents. Molecular Biology and Evolution. 19: 110-7. PMID 11752196  1
2002 Meiklejohn CD, Hartl DL. A single mode of canalization Trends in Ecology and Evolution. 17: 468-473. DOI: 10.1016/S0169-5347(02)02596-X  1
2001 Bustamante CD, Wakeley J, Sawyer S, Hartl DL. Directional selection and the site-frequency spectrum. Genetics. 159: 1779-88. PMID 11779814  1
2001 Tao Y, Hartl DL, Laurie CC. Sex-ratio segregation distortion associated with reproductive isolation in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 98: 13183-8. PMID 11687638 DOI: 10.1073/pnas.231478798  1
2001 Parsch J, Meiklejohn CD, Hartl DL. Patterns of DNA sequence variation suggest the recent action of positive selection in the janus-ocnus region of Drosophila simulans. Genetics. 159: 647-57. PMID 11606541  1
2001 Volkman SK, Barry AE, Lyons EJ, Nielsen KM, Thomas SM, Choi M, Thakore SS, Day KP, Wirth DF, Hartl DL. Recent origin of Plasmodium falciparum from a single progenitor. Science (New York, N.Y.). 293: 482-4. PMID 11463913 DOI: 10.1126/science.1059878  1
2001 Bensasson D, Zhang D, Hartl DL, Hewitt GM. Mitochondrial pseudogenes: evolution's misplaced witnesses. Trends in Ecology & Evolution. 16: 314-321. PMID 11369110 DOI: 10.1016/S0169-5347(01)02151-6  1
2001 Parsch J, Meiklejohn CD, Hauschteck-Jungen E, Hunziker P, Hartl DL. Molecular evolution of the ocnus and janus genes in the Drosophila melanogaster species subgroup. Molecular Biology and Evolution. 18: 801-11. PMID 11319264 DOI: 10.1093/oxfordjournals.molbev.a003862  1
2001 Bensasson D, Petrov DA, Zhang DX, Hartl DL, Hewitt GM. Genomic gigantism: DNA loss is slow in mountain grasshoppers. Molecular Biology and Evolution. 18: 246-53. PMID 11158383  1
2001 Hartl DL. Discovery of the transposable element mariner Genetics. 157: 471-476. PMID 11156971  1
2001 Nurminsky D, Aguiar DD, Bustamante CD, Hartl DL. Chromosomal effects of rapid gene evolution in Drosophila melanogaster. Science (New York, N.Y.). 291: 128-30. PMID 11141564 DOI: 10.1126/science.291.5501.128  1
2000 Townsend JP, Hartl DL. The kinetics of transposable element autoregulation. Genetica. 108: 229-37. PMID 11294609 DOI: 10.1023/A:1004172703790  1
2000 Hartl DL. Molecular melodies in high and low C. Nature Reviews. Genetics. 1: 145-9. PMID 11253654 DOI: 10.1038/35038580  1
2000 Goldfeld AE, Leung JY, Sawyer SA, Hartl DL. Post-genomics and the neutral theory: variation and conservation in the tumor necrosis factor-alpha promoter. Gene. 261: 19-25. PMID 11164033 DOI: 10.1016/S0378-1119(00)00477-7  1
2000 Cavalieri D, Townsend JP, Hartl DL. Manifold anomalies in gene expression in a vineyard isolate of Saccharomyces cerevisiae revealed by DNA microarray analysis. Proceedings of the National Academy of Sciences of the United States of America. 97: 12369-74. PMID 11035792 DOI: 10.1073/pnas.210395297  1
2000 Parsch J, Russell JA, Beerman I, Hartl DL, Stephan W. Deletion of a conserved regulatory element in the Drosophila Adh gene leads to increased alcohol dehydrogenase activity but also delays development. Genetics. 156: 219-27. PMID 10978287  1
2000 Leung JY, McKenzie FE, Uglialoro AM, Flores-Villanueva PO, Sorkin BC, Yunis EJ, Hartl DL, Goldfeld AE. Identification of phylogenetic footprints in primate tumor necrosis factor-alpha promoters. Proceedings of the National Academy of Sciences of the United States of America. 97: 6614-8. PMID 10841560 DOI: 10.1073/pnas.97.12.6614  1
2000 Siegal ML, Hartl DL. Application of Cre/loxP in Drosophila. Site-specific recombination and transgene coplacement. Methods in Molecular Biology (Clifton, N.J.). 136: 487-95. PMID 10840736 DOI: 10.1385/1-59259-065-9:487  1
2000 Petrov DA, Hartl DL. Pseudogene evolution and natural selection for a compact genome. The Journal of Heredity. 91: 221-7. PMID 10833048  1
2000 Hartl DL. Fly meets shotgun: shotgun wins. Nature Genetics. 24: 327-8. PMID 10742085 DOI: 10.1038/74125  1
2000 Bustamante CD, Townsend JP, Hartl DL. Solvent accessibility and purifying selection within proteins of Escherichia coli and Salmonella enterica. Molecular Biology and Evolution. 17: 301-8. PMID 10677853  1
2000 Petrov DA, Sangster TA, Johnston JS, Hartl DL, Shaw KL. Evidence for DNA loss as a determinant of genome size. Science (New York, N.Y.). 287: 1060-2. PMID 10669421 DOI: 10.1126/science.287.5455.1060  1
2000 Lohe AR, Timmons C, Beerman I, Lozovskaya ER, Hartl DL. Self-inflicted wounds, template-directed gap repair and a recombination hotspot. Effects of the mariner transposase. Genetics. 154: 647-56. PMID 10655218  1
1999 De Aguiar D, Hartl DL. Regulatory potential of nonautonomous mariner elements and subfamily crosstalk. Genetica. 107: 79-85. PMID 10952200  1
1999 Lozovskaya ER, Nurminsky DI, Petrov DA, Hartl DL. Genome size as a mutation-selection-drift process. Genes & Genetic Systems. 74: 201-7. PMID 10734601 DOI: 10.1266/ggs.74.201  1
1999 Siegal ML, Hartl DL. Oviposition-site preference in Drosophila following interspecific gene transfer of the Alcohol dehydrogenase locus. Behavior Genetics. 29: 199-204. PMID 10547927 DOI: 10.1023/A:1021648103496  1
1999 Charlesworth B, Charlesworth D, Nurminsky DI, Hartl DL. How was the Sdic gene fixed? [6] (multiple letters) Nature. 400: 519-520. PMID 10448854 DOI: 10.1038/22922  1
1999 Petrov DA, Hartl DL. Patterns of nucleotide substitution in Drosophila and mammalian genomes. Proceedings of the National Academy of Sciences of the United States of America. 96: 1475-9. PMID 9990048 DOI: 10.1073/pnas.96.4.1475  1
1999 Boyd EF, Hartl DL. Analysis of the type 1 pilin gene cluster fim in Salmonella: its distinct evolutionary histories in the 5' and 3' regions. Journal of Bacteriology. 181: 1301-8. PMID 9973358  1
1998 Petrov DA, Chao YC, Stephenson EC, Hartl DL. Pseudogene evolution in Drosophila suggests a high rate of DNA loss. Molecular Biology and Evolution. 15: 1562-7. PMID 12572619  1
1998 Siegal ML, Hartl DL. An experimental test for lineage-specific position effects on alcohol dehydrogenase (Adh) genes in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 95: 15513-8. PMID 9861000 DOI: 10.1073/pnas.95.26.15513  1
1998 Nurminsky DI, Nurminskaya MV, De Aguiar D, Hartl DL. Selective sweep of a newly evolved sperm-specific gene in Drosophila. Nature. 396: 572-5. PMID 9859991 DOI: 10.1038/25126  1
1998 Nurminsky DI, Nurminskaya MV, Benevolenskaya EV, Shevelyov YY, Hartl DL, Gvozdev VA. Cytoplasmic dynein intermediate-chain isoforms with different targeting properties created by tissue-specific alternative splicing. Molecular and Cellular Biology. 18: 6816-25. PMID 9774695  1
1998 Boyd EF, Hartl DL. Diversifying selection governs sequence polymorphism in the major adhesin proteins fimA, papA, and sfaA of Escherichia coli. Journal of Molecular Evolution. 47: 258-67. PMID 9732452 DOI: 10.1007/PL00006383  1
1998 Hartl DL, Taubes CH. Towards a theory of evolutionary adaptation. Genetica. 102: 525-33. PMID 9720296  0.32
1998 Vieira J, Vieira CP, Hartl DL, Lozovskaya ER. Factors contributing to the hybrid dysgenesis syndrome in Drosophila virilis. Genetical Research. 71: 109-17. PMID 9717433 DOI: 10.1017/S001667239800322X  1
1998 Boyd EF, Hartl DL. Salmonella virulence plasmid. Modular acquisition of the spv virulence region by an F-plasmid in Salmonella enterica subspecies I and insertion into the chromosome of subspecies II, IIIa, IV and VII isolates. Genetics. 149: 1183-90. PMID 9649513  1
1998 Moriyama EN, Petrov DA, Hartl DL. Genome size and intron size in Drosophila. Molecular Biology and Evolution. 15: 770-3. PMID 9615458  1
1998 Fadool JM, Hartl DL, Dowling JE. Transposition of the mariner element from Drosophila mauritiana in zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 95: 5182-6. PMID 9560250 DOI: 10.1073/pnas.95.9.5182  1
1998 Petrov DA, Hartl DL. High rate of DNA loss in the Drosophila melanogaster and Drosophila virilis species groups. Molecular Biology and Evolution. 15: 293-302. PMID 9501496  1
1998 Boyd EF, Hartl DL. Chromosomal regions specific to pathogenic isolates of Escherichia coli have a phylogenetically clustered distribution. Journal of Bacteriology. 180: 1159-65. PMID 9495754  1
1998 Petrov DA, Chao YC, Stephenson EC, Hartl DL. Pseudogene evolution in Drosophila suggests a high rate of DNA loss [1] Molecular Biology and Evolution. 15: 1562-1567.  1
1997 Petrov DA, Hartl DL. Trash DNA is what gets thrown away: high rate of DNA loss in Drosophila. Gene. 205: 279-89. PMID 9461402 DOI: 10.1016/S0378-1119(97)00516-7  1
1997 Hartl DL, Lohe AR, Lozovskaya ER. Modern thoughts on an ancyent marinere: function, evolution, regulation. Annual Review of Genetics. 31: 337-58. PMID 9442899 DOI: 10.1146/annurev.genet.31.1.337  1
1997 Hartl DL, Lohe AR, Lozovskaya ER. Regulation of the transposable element mariner. Genetica. 100: 177-84. PMID 9440271  1
1997 Vieira CP, Vieira J, Hartl DL. The evolution of small gene clusters: evidence for an independent origin of the maltase gene cluster in Drosophila virilis and Drosophila melanogaster. Molecular Biology and Evolution. 14: 985-93. PMID 9335139  1
1997 Vieira J, Vieira CP, Hartl DL, Lozovskaya ER. Discordant rates of chromosome evolution in the Drosophila virilis species group. Genetics. 147: 223-30. PMID 9286682  1
1997 Vieira J, Vieira CP, Hartl DL, Lozovskaya ER. A framework physical map of Drosophila virilis based on P1 clones: applications in genome evolution. Chromosoma. 106: 99-107. PMID 9215559 DOI: 10.1007/s004120050229  1
1997 Boyd EF, Hartl DL. Nonrandom location of IS1 elements in the genomes of natural isolates of Escherichia coli. Molecular Biology and Evolution. 14: 725-32. PMID 9214745  1
1997 Hartl DL. Mariner sails into Leishmania. Science (New York, N.Y.). 276: 1659-60. PMID 9206830 DOI: 10.1126/science.276.5319.1659  1
1997 Hartl DL, Lozovskaya ER, Nurminsky DI, Lohe AR. What restricts the activity of mariner-like transposable elements. Trends in Genetics : Tig. 13: 197-201. PMID 9154003 DOI: 10.1016/S0168-9525(97)01087-1  1
1997 Rich SM, Rosenthal BM, Telford SR, Spielman A, Hartl DL, Ayala FJ. Heterogeneity of the internal transcribed spacer (ITS-2) region within individual deer ticks. Insect Molecular Biology. 6: 123-9. PMID 9099576  1
1997 Boyd EF, Hartl DL. Recent horizontal transmission of plasmids between natural populations of Escherichia coli and Salmonella enterica. Journal of Bacteriology. 179: 1622-7. PMID 9045822  1
1997 Lohe AR, De Aguiar D, Hartl DL. Mutations in the mariner transposase: the D,D(35)E consensus sequence is nonfunctional. Proceedings of the National Academy of Sciences of the United States of America. 94: 1293-7. PMID 9037046 DOI: 10.1073/pnas.94.4.1293  1
1996 Hartl DL. EST! EST!! EST!!! Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 18: 1021-3. PMID 8976160 DOI: 10.1002/bies.950181213  1
1996 Hartl DL, Taubes CH. Compensatory nearly neutral mutations: selection without adaptation. Journal of Theoretical Biology. 182: 303-9. PMID 8944162 DOI: 10.1006/jtbi.1996.0168  1
1996 Petrov DA, Lozovskaya ER, Hartl DL. High intrinsic rate of DNA loss in Drosophila. Nature. 384: 346-9. PMID 8934517 DOI: 10.1038/384346a0  0.92
1996 Lohe AR, Sullivan DT, Hartl DL. Subunit interactions in the mariner transposase. Genetics. 144: 1087-95. PMID 8913752  1
1996 Siegal ML, Hartl DL. Transgene Coplacement and high efficiency site-specific recombination with the Cre/loxP system in Drosophila. Genetics. 144: 715-26. PMID 8889532  1
1996 Lohe AR, Hartl DL. Autoregulation of mariner transposase activity by overproduction and dominant-negative complementation. Molecular Biology and Evolution. 13: 549-55. PMID 8882498  1
1996 Coelho PA, Nurminsky D, Hartl D, Sunkel CE. Identification of Porto-1, a new repeated sequence that localises close to the centromere of chromosome 2 of Drosophila melanogaster. Chromosoma. 105: 211-22. PMID 8854880 DOI: 10.1007/s004120050177  1
1996 Lohe AR, Hartl DL. Reduced germline mobility of a mariner vector containing exogenous DNA: effect of size or site? Genetics. 143: 1299-306. PMID 8807301  1
1996 Lozovskaya ER, Nurminsky DI, Hartl DL, Sullivan DT. Germline transformation of Drosophila virilis mediated by the transposable element hobo. Genetics. 142: 173-7. PMID 8770594  1
1996 Lohe AR, Hartl DL. Germline transformation of Drosophila virilis with the transposable element mariner. Genetics. 143: 365-74. PMID 8722788  1
1996 Hartl DL, Ochman H. Inverse polymerase chain reaction. Methods in Molecular Biology (Clifton, N.J.). 58: 293-301. PMID 8713876 DOI: 10.1385/0-89603-402-X:293  1
1996 Nurminsky DI, Hartl DL. Sequence scanning: A method for rapid sequence acquisition from large-fragment DNA clones. Proceedings of the National Academy of Sciences of the United States of America. 93: 1694-8. PMID 8643692  1
1996 Robertson HM, Zumpano KL, Lohe AR, Hartl DL. Reconstructing the ancient mariners of humans. Nature Genetics. 12: 360-1. PMID 8630486 DOI: 10.1038/ng0496-360  1
1996 Nurminsky DI, Moriyama EN, Lozovskaya ER, Hartl DL. Molecular phylogeny and genome evolution in the Drosophila virilis species group: duplications of the alcohol dehydrogenase gene. Molecular Biology and Evolution. 13: 132-49. PMID 8583887  1
1995 Lozovskaya ER, Hartl DL, Petrov DA. Genomic regulation of transposable elements in Drosophila. Current Opinion in Genetics & Development. 5: 768-73. PMID 8745075 DOI: 10.1016/0959-437X(95)80009-T  1
1995 Segarra C, Lozovskaya ER, Ribó G, Aguadé M, Hartl DL. P1 clones from Drosophila melanogaster as markers to study the chromosomal evolution of Muller's A element in two species of the obscura group of Drosophila. Chromosoma. 104: 129-36. PMID 8585990 DOI: 10.1007/BF00347695  1
1995 Lohe AR, Moriyama EN, Lidholm DA, Hartl DL. Horizontal transmission, vertical inactivation, and stochastic loss of mariner-like transposable elements. Molecular Biology and Evolution. 12: 62-72. PMID 7877497  1
1995 Petrov DA, Schutzman JL, Hartl DL, Lozovskaya ER. Diverse transposable elements are mobilized in hybrid dysgenesis in Drosophila virilis. Proceedings of the National Academy of Sciences of the United States of America. 92: 8050-4. PMID 7644536 DOI: 10.1073/pnas.92.17.8050  1
1995 Lohe AR, Lidholm DA, Hartl DL. Genotypic effects, maternal effects and grand-maternal effects of immobilized derivatives of the transposable element mariner. Genetics. 140: 183-92. PMID 7635283  1
1995 Chang BS, Crandall KA, Carulli JP, Hartl DL. Opsin phylogeny and evolution: a model for blue shifts in wavelength regulation. Molecular Phylogenetics and Evolution. 4: 31-43. PMID 7620634 DOI: 10.1006/mpev.1995.1004  1
1995 Rich SM, Caporale DA, Telford SR, Kocher TD, Hartl DL, Spielman A. Distribution of the Ixodes ricinus-like ticks of eastern North America. Proceedings of the National Academy of Sciences of the United States of America. 92: 6284-8. PMID 7603983 DOI: 10.1073/pnas.92.14.6284  1
1994 Hartl DL, Nurminsky DI, Jones RW, Lozovskaya ER. Genome structure and evolution in Drosophila: applications of the framework P1 map. Proceedings of the National Academy of Sciences of the United States of America. 91: 6824-9. PMID 8041703 DOI: 10.1073/pnas.91.15.6824  1
1994 Lewontin RC, Hartl DL. Forensic DNA typing dispute [1] Nature. 372: 398-399. PMID 7984229 DOI: 10.1038/372398B0  1
1994 Ayala FJ, Krane DE, Hartl DL. Genetic variation in IncI1-ColIb plasmids. Journal of Molecular Evolution. 39: 129-33. PMID 7932776 DOI: 10.1007/BF00163801  0.32
1994 Hartl DL, Ochman H. Inverse polymerase chain reaction. Methods in Molecular Biology (Clifton, N.J.). 31: 187-96. PMID 7921017 DOI: 10.1385/0-89603-258-2:187  1
1994 Hartl DL, Lewontin RC. DNA fingerprinting. Science (New York, N.Y.). 266: 201; author reply 20. PMID 7802835 DOI: 10.1126/science.7802835  1
1993 Lawrence JG, Hartl DL, Ochman H. Sequencing products of polymerase chain reaction. Methods in Enzymology. 218: 26-35. PMID 8510537  1
1993 Lozovskaya ER, Petrov DA, Hartl DL. A combined molecular and cytogenetic approach to genome evolution in Drosophila using large-fragment DNA cloning. Chromosoma. 102: 253-66. PMID 8486077  1
1993 Hartl DL, Lewontin RC. DNA fingerprinting report. Science (New York, N.Y.). 260: 473-4. PMID 8475378 DOI: 10.1126/science.8475378  1
1993 Ochman H, Ayala FJ, Hartl DL. Use of polymerase chain reaction to amplify segments outside boundaries of known sequences Methods in Enzymology. 218: 309-321. PMID 8389965 DOI: 10.1016/0076-6879(93)18023-6  1
1993 Nurminsky DI, Hartl DL. Amplification of the ends of DNA fragments cloned in bacteriophage P1. Biotechniques. 15: 201-2, 206-8. PMID 8373578  1
1992 Lawrence JG, Hartl DL. Inference of horizontal genetic transfer from molecular data: an approach using the bootstrap. Genetics. 131: 753-60. PMID 1628816  1
1992 Hartl DL, Ajioka JW, Cai H, Lohe AR, Lozovskaya ER, Smoller DA, Duncan IW. Towards a Drosophila genome map. Trends in Genetics : Tig. 8: 70-5. PMID 1566375 DOI: 10.1016/0168-9525(92)90353-6  1
1992 Krane DE, Allen RW, Sawyer SA, Petrov DA, Hartl DL. Genetic differences at four DNA typing loci in Finnish, Italian, and mixed Caucasian populations. Proceedings of the National Academy of Sciences of the United States of America. 89: 10583-7. PMID 1438254  1
1992 Hartl DL, Lozovskaya ER, Lawrence JG. Nonautonomous transposable elements in prokaryotes and eukaryotes. Genetica. 86: 47-53. PMID 1334917 DOI: 10.1007/BF00133710  1
1992 Capy P, David JR, Hartl DL. Evolution of the transposable element mariner in the Drosophila melanogaster species group. Genetica. 86: 37-46. PMID 1334916 DOI: 10.1007/BF00133709  1
1992 Lawrence JG, Ochman H, Hartl DL. The evolution of insertion sequences within enteric bacteria. Genetics. 131: 9-20. PMID 1317318  1
1992 Danilevskaya ON, Petrov DA, Pavlova MN, Koga A, Kurenova EV, Hartl DL. A repetitive DNA element, associated with telomeric sequences in Drosophila melanogaster, contains open reading frames. Chromosoma. 102: 32-40. PMID 1291227 DOI: 10.1007/BF00352288  1
1991 Lawrence JG, Ochman H, Hartl DL. Molecular and evolutionary relationships among enteric bacteria. Journal of General Microbiology. 137: 1911-21. PMID 1955870  1
1991 Merriam J, Ashburner M, Hartl DL, Kafatos FC. Toward cloning and mapping the genome of Drosophila. Science (New York, N.Y.). 254: 221-5. PMID 1925579 DOI: 10.1126/SCIENCE.1925579  1
1991 Palazzolo MJ, Sawyer SA, Martin CH, Smoller DA, Hartl DL. Optimized strategies for sequence-tagged-site selection in genome mapping. Proceedings of the National Academy of Sciences of the United States of America. 88: 8034-8. PMID 1896449  1
1991 Lewontin RC, Hartl DL. Population genetics in forensic DNA typing. Science (New York, N.Y.). 254: 1745-50. PMID 1845040 DOI: 10.1126/SCIENCE.1845040  1
1991 Krane DE, Hartl DL, Ochman H. Rapid determination of nucleotide content and its application to the study of genome structure Nucleic Acids Research. 19: 5181-5185. PMID 1833723 DOI: 10.1093/NAR/19.19.5181  1
1991 Ajioka JW, Smoller DA, Jones RW, Carulli JP, Vellek AE, Garza D, Link AJ, Duncan IW, Hartl DL. Drosophila genome project: one-hit coverage in yeast artificial chromosomes. Chromosoma. 100: 495-509. PMID 1764968 DOI: 10.1007/BF00352200  1
1991 Smoller DA, Petrov D, Hartl DL. Characterization of bacteriophage P1 library containing inserts of Drosophila DNA of 75-100 kilobase pairs. Chromosoma. 100: 487-94. PMID 1764967  0.68
1991 Lawrence JG, Hartl DL, Ochman H. Molecular considerations in the evolution of bacterial genes. Journal of Molecular Evolution. 33: 241-50. PMID 1757995 DOI: 10.1007/BF02100675  1
1991 Capy P, Maruyama K, David JR, Hartl DL. Insertion sites of the transposable element mariner are fixed in the genome of Drosophila sechellia. Journal of Molecular Evolution. 33: 450-6. PMID 1660073 DOI: 10.1007/BF02103137  1
1991 Lawrence JG, Hartl DL. Unusual codon bias occurring within insertion sequences in Escherichia coli. Genetica. 84: 23-9. PMID 1651881 DOI: 10.1007/BF00123981  1
1991 Garza D, Medhora M, Koga A, Hartl DL. Introduction of the transposable element mariner into the germline of Drosophila melanogaster. Genetics. 128: 303-10. PMID 1649067  1
1991 Danilevskaya ON, Kurenova EV, Pavlova MN, Bebehov DV, Link AJ, Koga A, Vellek A, Hartl DL. He-T family DNA sequences in the Y chromosome of Drosophila melanogaster share homology with the X-linked Stellate genes Chromosoma. 100: 118-124. DOI: 10.1007/BF00418245  1
1990 Garza D, Medhora MM, Hartl DL. Drosophila nonsense suppressors: functional analysis in Saccharomyces cerevisiae, Drosophila tissue culture cells and Drosophila melanogaster. Genetics. 126: 625-37. PMID 2174393  1
1990 Capy P, Chakrani F, Lemeunier F, Hartl DL, David JR. Active mariner transposable elements are widespread in natural populations of Drosophila simulans. Proceedings. Biological Sciences / the Royal Society. 242: 57-60. PMID 1980741 DOI: 10.1098/rspb.1990.0103  1
1990 Ochman H, Ajioka JW, Garza D, Hartl DL. Inverse polymerase chain reaction. Bio/Technology (Nature Publishing Company). 8: 759-60. PMID 1366903 DOI: 10.1038/nbt0890-759  1
1989 Lawrence JG, Dykhuizen DE, DuBose RF, Hartl DL. Phylogenetic analysis using insertion sequence fingerprinting in Escherichia coli. Molecular Biology and Evolution. 6: 1-14. PMID 2564160  1
1989 Garza D, Ajioka JW, Burke DT, Hartl DL. Mapping the Drosophila genome with yeast artificial chromosomes. Science (New York, N.Y.). 246: 641-6. PMID 2510296  1
1988 Stebbins GL, Hartl DL. Comparative evolution: latent potentials for anagenetic advance. Proceedings of the National Academy of Sciences of the United States of America. 85: 5141-5. PMID 3293050 DOI: 10.1073/PNAS.85.14.5141  1
1988 Dean AM, Dykhuizen DE, Hartl DL. Fitness effects of amino acid replacements in the beta-galactosidase of Escherichia coli. Molecular Biology and Evolution. 5: 469-85. PMID 3143044  1
1988 DuBose RF, Dykhuizen DE, Hartl DL. Genetic exchange among natural isolates of bacteria: recombination within the phoA gene of Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 85: 7036-40. PMID 3045828  1
1988 Miller RD, Dykhuizen DE, Hartl DL. Fitness effects of a deletion mutation increasing transcription of the 6-phosphogluconate dehydrogenase gene in Escherichia coli. Molecular Biology and Evolution. 5: 691-703. PMID 2464736  1
1987 Sawyer SA, Dykhuizen DE, Hartl DL. Confidence interval for the number of selectively neutral amino acid polymorphisms. Proceedings of the National Academy of Sciences of the United States of America. 84: 6225-8. PMID 3306673  1
1987 Dykhuizen DE, Dean AM, Hartl DL. Metabolic flux and fitness. Genetics. 115: 25-31. PMID 3104135  1
1987 Sawyer SA, Dykhuizen DE, DuBose RF, Green L, Mutangadura-Mhlanga T, Wolczyk DF, Hartl DL. Distribution and abundance of insertion sequences among natural isolates of Escherichia coli. Genetics. 115: 51-63. PMID 3030884  1
1986 Miller RD, Hartl DL. BIOTYPING CONFIRMS A NEARLY CLONAL POPULATION STRUCTURE IN ESCHERICHIA COLI. Evolution; International Journal of Organic Evolution. 40: 1-12. PMID 28564121 DOI: 10.1111/j.1558-5646.1986.tb05712.x  0.52
1986 Hartl DL, Dean AM, Dykhuizen DE. The molecular biology of natural selection: reply to burton and place. Genetics. 114: 1037-9. PMID 17246353  1
1986 Dean AM, Dykhuizen DE, Hartl DL. Fitness as a function of beta-galactosidase activity in Escherichia coli. Genetical Research. 48: 1-8. PMID 3096817  1
1986 Hartl DL, Medhora M, Green L, Dykhuizen DE. The evolution of DNA sequences in Escherichia coli. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 312: 191-204. PMID 2870515  1
1985 Dykhuizen DE, Mudd C, Honeycutt A, Hartl DL. POLYMORPHIC POSTTRANSLATIONAL MODIFICATION OF ALKALINE PHOSPHATASE IN ESCHERICHIA COLI. Evolution; International Journal of Organic Evolution. 39: 1-7. PMID 28563640 DOI: 10.1111/j.1558-5646.1985.tb04075.x  1
1985 Hartl DL, Dykhuizen DE, Dean AM. Limits of adaptation: the evolution of selective neutrality. Genetics. 111: 655-74. PMID 3932127  1
1985 Behlke MA, Spinella DG, Chou HS, Sha W, Hartl DL, Loh DY. T-cell receptor β-chain expression: Dependence on relatively few variable region genes Science. 229: 566-570. PMID 3875151 DOI: 10.1126/science.3875151  1
1985 Dykhuizen DE, Sawyer SA, Green L, Miller RD, Hartl DL. Joint distribution of insertion elements IS4 and IS5 in natural isolates of Escherichia coli. Genetics. 111: 219-31. PMID 2996976  1
1984 Dykhuizen DE, de Framond J, Hartl DL. Selective neutrality of glucose-6-phosphate dehydrogenase allozymes in Escherichia coli. Molecular Biology and Evolution. 1: 162-70. PMID 6400649  1
1984 Miller RD, Dykhuizen DE, Green L, Hartl DL. Specific deletion occurring in the directed evolution of 6-phosphogluconate dehydrogenase in Escherichia coli. Genetics. 108: 765-72. PMID 6392014  1
1984 Dykhuizen DE, de Framond J, Hartl DL. Potential for hitchhiking in the eda-edd-zwf gene cluster of Escherichia coli. Genetical Research. 43: 229-39. PMID 6381229  1
1984 Hartl DL, Dykhuizen DE, Berg DE. Accessory DNAs in the bacterial gene pool: playground for coevolution. Ciba Foundation Symposium. 102: 233-45. PMID 6319094 DOI: 10.1002/9780470720837.ch15  1
1984 Hartl DL, Dykhuizen DE. The population genetics of Escherichia coli. Annual Review of Genetics. 18: 31-68. PMID 6099090 DOI: 10.1146/annurev.ge.18.120184.000335  1
1984 Green L, Miller RD, Dykhuizen DE, Hartl DL. Distribution of DNA insertion element IS5 in natural isolates of Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 81: 4500-4. PMID 6087327  1
1983 Dykhuizen DE, Hartl DL. Functional effects of PGI allozymes in Escherichia coli. Genetics. 105: 1-18. PMID 6352406  1
1983 Hartl DL, Dykhuizen DE, Miller RD, Green L, de Framond J. Transposable element IS50 improves growth rate of E. coli cells without transposition. Cell. 35: 503-10. PMID 6317194 DOI: 10.1016/0092-8674(83)90184-8  1
1983 Dykhuizen DE, Hartl DL. Selection in chemostats. Microbiological Reviews. 47: 150-68. PMID 6308409  1
1981 Dykhuizen D, Hartl D. EVOLUTION OF COMPETITIVE ABILITY IN ESCHERICHIA COLI. Evolution; International Journal of Organic Evolution. 35: 581-594. PMID 28563589 DOI: 10.1111/j.1558-5646.1981.tb04919.x  1
1981 Hartl DL, Dykhuizen DE. Potential for selection among nearly neutral allozymes of 6-phosphogluconate dehydrogenase in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 78: 6344-8. PMID 7031648  1
1980 Dykhuizen D, Hartl DL. Selective neutrality of 6PGD allozymes in E. coli and the effects of genetic background. Genetics. 96: 801-17. PMID 7021316  1
1978 Dykhuizen D, Hartl D. Transport by the lactose permease of Escherichia coli as the basis of lactose killing. Journal of Bacteriology. 135: 876-82. PMID 99437 DOI: 10.1128/JB.135.3.876-882.1978  1
1967 Hartl DL, Hiraizumi Y, Crow JF. Evidence for sperm dysfunction as the mechanism of segregation distortion in Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America. 58: 2240-5. PMID 5242201  1
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