Ivona Pandrea - Publications

Affiliations: 
Microbiology & Immunology Tulane University, New Orleans, LA, United States 
Area:
Microbiology Biology, Immunology

112 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Symmonds J, Gaufin T, Xu C, Raehtz KD, Ribeiro RM, Pandrea I, Apetrei C. Making a Monkey out of Human Immunodeficiency Virus/Simian Immunodeficiency Virus Pathogenesis: Immune Cell Depletion Experiments as a Tool to Understand the Immune Correlates of Protection and Pathogenicity in HIV Infection. Viruses. 16. PMID 38932264 DOI: 10.3390/v16060972  0.456
2023 Policicchio BB, Cardozo-Ojeda EF, Xu C, Ma D, He T, Raehtz KD, Sivanandham R, Kleinman AJ, Perelson AS, Apetrei C, Pandrea I, Ribeiro RM. CD8 T cells control SIV infection using both cytolytic effects and non-cytolytic suppression of virus production. Nature Communications. 14: 6657. PMID 37863982 DOI: 10.1038/s41467-023-42435-8  0.545
2023 Apetrei C, Gaufin T, Brocca-Cofano E, Sivanandham R, Sette P, He T, Sivanandham S, Martinez Sosa N, Martin KJ, Raehtz KD, Kleinman AJ, Valentine A, Krampe N, Gautam R, Lackner AA, ... ... Pandrea I, et al. T cell activation is insufficient to drive SIV disease progression. Jci Insight. 8. PMID 37485874 DOI: 10.1172/jci.insight.161111  0.385
2023 Le Hingrat Q, Sette P, Xu C, Rahmberg AR, Tarnus L, Annapureddy H, Kleinman A, Brocca-Cofano E, Sivanandham R, Sivanandham S, He T, Capreri DJ, Ma D, Estes JD, Brenchley JM, ... ... Pandrea I, et al. Prolonged experimental CD4 T-cell depletion does not cause disease progression in SIV-infected African green monkeys. Nature Communications. 14: 979. PMID 36813761 DOI: 10.1038/s41467-023-36379-2  0.531
2023 Jasinska AJ, Apetrei C, Pandrea I. Walk on the wild side: SIV infection in African non-human primate hosts-from the field to the laboratory. Frontiers in Immunology. 13: 1060985. PMID 36713371 DOI: 10.3389/fimmu.2022.1060985  0.574
2022 Pandrea I, Brooks K, Desai RP, Tare M, Brenchley JM, Apetrei C. I've looked at gut from both sides now: Gastrointestinal tract involvement in the pathogenesis of SARS-CoV-2 and HIV/SIV infections. Frontiers in Immunology. 13: 899559. PMID 36032119 DOI: 10.3389/fimmu.2022.899559  0.48
2022 Ma H, Albe JR, Gilliland T, McMillen CM, Gardner CL, Boyles DA, Cottle EL, Dunn MD, Lundy JD, Salama N, O'Malley KJ, Pandrea I, Teichert T, Barrick S, Klimstra WB, et al. Long-term persistence of viral RNA and inflammation in the CNS of macaques exposed to aerosolized Venezuelan equine encephalitis virus. Plos Pathogens. 18: e1009946. PMID 35696423 DOI: 10.1371/journal.ppat.1009946  0.4
2022 Kleinman AJ, Sivanandham S, Sette P, Sivanandham R, Policicchio BB, Xu C, Penn E, Brocca-Cofano E, Le Hingrat Q, Ma D, Pandrea I, Apetrei C. Changes to the Simian Immunodeficiency Virus (SIV) Reservoir and Enhanced SIV-Specific Responses in a Rhesus Macaque Model of Functional Cure after Serial Rounds of Romidepsin Administrations. Journal of Virology. e0044522. PMID 35638831 DOI: 10.1128/jvi.00445-22  0.512
2022 Jasinska AJ, Pandrea I, Apetrei C. CCR5 as a Coreceptor for Human Immunodeficiency Virus and Simian Immunodeficiency Viruses: A Prototypic Love-Hate Affair. Frontiers in Immunology. 13: 835994. PMID 35154162 DOI: 10.3389/fimmu.2022.835994  0.579
2022 Kleinman AJ, Pandrea I, Apetrei C. So Pathogenic or So What?-A Brief Overview of SIV Pathogenesis with an Emphasis on Cure Research. Viruses. 14. PMID 35062339 DOI: 10.3390/v14010135  0.347
2021 Le Hingrat Q, Sereti I, Landay AL, Pandrea I, Apetrei C. The Hitchhiker Guide to CD4 T-Cell Depletion in Lentiviral Infection. A Critical Review of the Dynamics of the CD4 T Cells in SIV and HIV Infection. Frontiers in Immunology. 12: 695674. PMID 34367156 DOI: 10.3389/fimmu.2021.695674  0.525
2021 Kleinman A, Sivanandham R, Sette P, Brocca-Cofano E, McAndrews C, Keele B, Pandrea I, Apetrei C. Lack of Specific Regulatory T-Cell Depletion and Cytoreduction Associated with Extensive Toxicity after Administration of Low and High Doses of Cyclophosphamide. Aids Research and Human Retroviruses. PMID 33957772 DOI: 10.1089/AID.2021.0036  0.352
2021 Li H, Wang S, Lee FH, Roark RS, Murphy AI, Smith J, Zhao C, Rando J, Chohan N, Ding Y, Kim E, Lindemuth E, Bar KJ, Pandrea I, Apetrei C, et al. New SHIVs and Improved Design Strategy for Modeling HIV-1 Transmission, Immunopathogenesis, Prevention and Cure. Journal of Virology. PMID 33658341 DOI: 10.1128/JVI.00071-21  0.452
2021 Albe JR, Ma H, Gilliland TH, McMillen CM, Gardner CL, Boyles DA, Cottle EL, Dunn MD, Lundy JD, O'Malley KJ, Salama N, Walters AW, Pandrea I, Teichert T, Klimstra WB, et al. Physiological and immunological changes in the brain associated with lethal eastern equine encephalitis virus in macaques. Plos Pathogens. 17: e1009308. PMID 33534855 DOI: 10.1371/journal.ppat.1009308  0.411
2020 Jasinska AJ, Dong TS, Lagishetty V, Katzka W, Jacobs JP, Schmitt CA, Cramer JD, Ma D, Coetzer WG, Grobler JP, Turner TR, Freimer N, Pandrea I, Apetrei C. Shifts in microbial diversity, composition, and functionality in the gut and genital microbiome during a natural SIV infection in vervet monkeys. Microbiome. 8: 154. PMID 33158452 DOI: 10.1186/s40168-020-00928-4  0.417
2020 Sivanandham R, Kleinman AJ, Sette P, Brocca-Cofano E, Kilapandal Venkatraman SM, Policicchio BB, He T, Xu C, Swarthout J, Wang Z, Pandrea I, Apetrei C. Nonhuman Primate Testing of the Impact of Different Treg Depletion Strategies on Reactivation and Clearance of Latent Simian Immunodeficiency Virus. Journal of Virology. PMID 32669326 DOI: 10.1128/Jvi.00533-20  0.522
2020 Raehtz KD, Barrenäs F, Xu C, Busman-Sahay K, Valentine A, Law L, Ma D, Policicchio BB, Wijewardana V, Brocca-Cofano E, Trichel A, Gale M, Keele BF, Estes JD, Apetrei C, ... Pandrea I, et al. African green monkeys avoid SIV disease progression by preventing intestinal dysfunction and maintaining mucosal barrier integrity. Plos Pathogens. 16: e1008333. PMID 32119719 DOI: 10.1371/Journal.Ppat.1008333  0.561
2020 Jasinska AJ, Pandrea I, He T, Benjamin C, Newton M, Lee JC, Freimer NB, Coppola G, Jentsch JD. Immunosuppressive effect and global dysregulation of blood transcriptome in response to psychosocial stress in vervet monkeys (Chlorocebus sabaeus). Scientific Reports. 10: 3459. PMID 32103041 DOI: 10.1038/S41598-020-59934-Z  0.36
2019 He T, Xu C, Krampe N, Dillon SM, Sette P, Falwell E, Haret-Richter GS, Butterfield T, Dunsmore TL, Jr WMM, Martin KJ, Policicchio BB, Raehtz KD, Penn EP, Tracy RP, ... ... Pandrea I, et al. High-fat diet exacerbates SIV pathogenesis and accelerates disease progression. The Journal of Clinical Investigation. PMID 31710311 DOI: 10.1172/Jci121208  0.456
2019 Barrenas F, Raehtz K, Xu C, Law L, Green RR, Silvestri G, Bosinger SE, Nishida A, Li Q, Lu W, Zhang J, Thomas MJ, Chang J, Smith E, Weiss JM, ... ... Pandrea I, et al. Macrophage-associated wound healing contributes to African green monkey SIV pathogenesis control. Nature Communications. 10: 5101. PMID 31704931 DOI: 10.1038/S41467-019-12987-9  0.407
2019 Kleinman A, Venkatraman SMK, Penn E, Policicchio B, Sette P, Brocca-Cofano E, Cottrell M, Sivanandham R, Valentine A, Xu C, Raehtz K, Dunsmore T, Haret-Richter G, Kashuba A, Mellors J, ... Pandrea I, et al. Different regimens of romidepsin administration for reversion of SIV latency in a rhesus macaque model of complete virus control Journal of Virus Eradication. 5: 13. DOI: 10.1016/S2055-6640(20)31045-1  0.376
2018 Sivanandham R, Brocca-Cofano E, Krampe N, Falwell E, Kilapandal Venkatraman SM, Ribeiro RM, Apetrei C, Pandrea I. Neutrophil extracellular trap production contributes to pathogenesis in SIV-infected nonhuman primates. The Journal of Clinical Investigation. PMID 30204591 DOI: 10.1172/Jci99420  0.608
2018 Cardozo EF, Apetrei C, Pandrea I, Ribeiro RM. The dynamics of simian immunodeficiency virus after depletion of CD8+ cells. Immunological Reviews. 285: 26-37. PMID 30129200 DOI: 10.1111/Imr.12691  0.552
2018 Brocca-Cofano E, Xu C, Wetzel KS, Cottrell ML, Policicchio BB, Raehtz KD, Ma D, Dunsmore T, Haret-Richter GS, Musaitif K, Keele BF, Kashuba AD, Collman RG, Pandrea I, Apetrei C. Marginal Effects of Systemic CCR5 Blockade with Maraviroc on Oral Simian Immunodeficiency Virus Transmission to Infant Macaques. Journal of Virology. PMID 29925666 DOI: 10.1128/Jvi.00576-18  0.54
2018 Kleinman AJ, Sivanandham R, Pandrea I, Chougnet CA, Apetrei C. Regulatory T Cells As Potential Targets for HIV Cure Research. Frontiers in Immunology. 9: 734. PMID 29706961 DOI: 10.3389/Fimmu.2018.00734  0.511
2018 Policicchio BB, Cardozo EF, Sette P, Xu C, Haret-Richter G, Dunsmore T, Apetrei C, Pandrea I, Ribeiro RM. The dynamics of SIV 2-LTR Circles in the Presence and Absence of CD8 Cells. Journal of Virology. PMID 29643246 DOI: 10.1128/Jvi.02100-17  0.6
2018 Policicchio BB, Sette P, Xu C, Haret-Richter G, Dunsmore T, Pandrea I, Ribeiro RM, Apetrei C. Emergence of resistance mutations in simian immunodeficiency virus (SIV)-infected rhesus macaques receiving non-suppressive antiretroviral therapy (ART). Plos One. 13: e0190908. PMID 29466356 DOI: 10.1371/Journal.Pone.0190908  0.474
2017 Brocca-Cofano E, Kuhrt D, Siewe B, Xu C, Haret-Richter GS, Craigo J, Labranche C, Montefiori DC, Landay A, Apetrei C, Pandrea I. Pathogenic Correlates of the Simian Immunodeficiency Virus (SIV)-Associated B Cell Dysfunction. Journal of Virology. PMID 28931679 DOI: 10.1128/Jvi.01051-17  0.506
2017 Schechter ME, Andrade BB, He T, Richter GH, Tosh KW, Policicchio BB, Singh A, Raehtz KD, Sheikh V, Ma D, Brocca-Cofano E, Apetrei C, Tracy R, Ribeiro RM, Sher A, ... ... Pandrea I, et al. Inflammatory monocytes expressing tissue factor drive SIV and HIV coagulopathy. Science Translational Medicine. 9. PMID 28855397 DOI: 10.1126/Scitranslmed.Aam5441  0.489
2017 He T, Falwell E, Brocca-Cofano E, Pandrea I. Modeling aging in HIV infection in nonhuman primates to address an emerging challenge of the post-ART era. Current Opinion in Virology. 25: 66-75. PMID 28803049 DOI: 10.1016/J.Coviro.2017.07.012  0.487
2016 Wetzel KS, Yi Y, Elliott ST, Romero D, Jacquelin B, Hahn BH, Muller-Trutwin M, Apetrei C, Pandrea I, Collman RG. CXCR6-mediated SIVagmSab Entry into Sabaeus African Green Monkey Lymphocytes Implicates Widespread Use of Non-CCR5 Pathways in Natural Host Infections. Journal of Virology. PMID 27903799 DOI: 10.1128/Jvi.01626-16  0.608
2016 He T, Brocca-Cofano E, Policicchio BB, Sivanandham R, Gautam R, Raehtz KD, Xu C, Pandrea I, Apetrei C. Cutting Edge: T Regulatory Cell Depletion Reactivates Latent Simian Immunodeficiency Virus (SIV) in Controller Macaques While Boosting SIV-Specific T Lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). PMID 27837106 DOI: 10.4049/Jimmunol.1601539  0.589
2016 Policicchio BB, Xu C, Brocca-Cofano E, Raehtz KD, He T, Ma D, Li H, Sivanandham R, Haret-Richter GS, Dunsmore T, Trichel A, Mellors JW, Hahn BH, Shaw GM, Ribeiro RM, ... Pandrea I, et al. Multi-dose Romidepsin Reactivates Replication Competent SIV in Post-antiretroviral Rhesus Macaque Controllers. Plos Pathogens. 12: e1005879. PMID 27632364 DOI: 10.1371/Journal.Ppat.1005879  0.585
2016 Raehtz K, Pandrea I, Apetrei C. The well-tempered SIV infection: Pathogenesis of SIV infection in natural hosts in the wild, with emphasis on virus transmission and early events post-infection that may contribute to protection from disease progression. Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases. PMID 27394696 DOI: 10.1016/J.Meegid.2016.07.006  0.593
2016 Li H, Wang S, Kong R, Ding W, Lee FH, Parker Z, Kim E, Learn GH, Hahn P, Policicchio B, Brocca-Cofano E, Deleage C, Hao X, Chuang GY, Gorman J, ... ... Pandrea I, et al. Envelope residue 375 substitutions in simian-human immunodeficiency viruses enhance CD4 binding and replication in rhesus macaques. Proceedings of the National Academy of Sciences of the United States of America. PMID 27247400 DOI: 10.1073/Pnas.1606636113  0.526
2016 Policicchio BB, Pandrea I, Apetrei C. Animal Models for HIV Cure Research. Frontiers in Immunology. 7: 12. PMID 26858716 DOI: 10.3389/Fimmu.2016.00012  0.466
2016 Pandrea I, Xu C, Stock JL, Frank DN, Ma D, Policicchio BB, He T, Kristoff J, Cornell E, Haret-Richter GS, Trichel A, Ribeiro RM, Tracy R, Wilson C, Landay AL, et al. Antibiotic and Antiinflammatory Therapy Transiently Reduces Inflammation and Hypercoagulation in Acutely SIV-Infected Pigtailed Macaques. Plos Pathogens. 12: e1005384. PMID 26764484 DOI: 10.1371/Journal.Ppat.1005384  0.568
2015 Vujkovic-Cvijin I, Swainson LA, Chu SN, Ortiz AM, Santee CA, Petriello A, Dunham RM, Fadrosh DW, Lin DL, Faruqi AA, Huang Y, Apetrei C, Pandrea I, Hecht FM, Pilcher CD, et al. Gut-Resident Lactobacillus Abundance Associates with IDO1 Inhibition and Th17 Dynamics in SIV-Infected Macaques. Cell Reports. 13: 1589-97. PMID 26586432 DOI: 10.1016/J.Celrep.2015.10.026  0.559
2015 Hao XP, Lucero CM, Turkbey B, Bernardo ML, Morcock DR, Deleage C, Trubey CM, Smedley J, Klatt NR, Giavedoni LD, Kristoff J, Xu A, Del Prete GQ, Keele BF, Rao SS, ... ... Pandrea I, et al. Experimental colitis in SIV-uninfected rhesus macaques recapitulates important features of pathogenic SIV infection. Nature Communications. 6: 8020. PMID 26282376 DOI: 10.1038/Ncomms9020  0.545
2015 He T, Brocca-Cofano E, Gillespie DG, Xu C, Stock JL, Ma D, Policicchio BB, Raehtz KD, Rinaldo CR, Apetrei C, Jackson EK, Macatangay BJ, Pandrea I. Critical Role for the Adenosine Pathway in Controlling Simian Immunodeficiency Virus-Related Immune Activation and Inflammation in Gut Mucosal Tissues. Journal of Virology. 89: 9616-30. PMID 26178986 DOI: 10.1128/Jvi.01196-15  0.622
2015 Policicchio BB, Pandrea I, Apetrei C. Population Bottlenecks and Pathogen Extinction: "Make This Everyone's Mission to Mars, Including Yours". Journal of Virology. 89: 8104-6. PMID 26018162 DOI: 10.1128/Jvi.00920-15  0.346
2015 Ma D, Xu C, Cillo AR, Policicchio B, Kristoff J, Haret-Richter G, Mellors JW, Pandrea I, Apetrei C. Simian Immunodeficiency Virus SIVsab Infection of Rhesus Macaques as a Model of Complete Immunological Suppression with Persistent Reservoirs of Replication-Competent Virus: Implications for Cure Research. Journal of Virology. 89: 6155-60. PMID 25833043 DOI: 10.1128/Jvi.00256-15  0.534
2015 Pandrea I, Landay A, Wilson C, Stock J, Tracy R, Apetrei C. Using the pathogenic and nonpathogenic nonhuman primate model for studying non-AIDS comorbidities. Current Hiv/Aids Reports. 12: 54-67. PMID 25604236 DOI: 10.1007/S11904-014-0245-5  0.489
2015 Hao XP, Lucero CM, Turkbey B, Bernardo ML, Morcock DR, Deleage C, Trubey CM, Smedley J, Klatt NR, Giavedoni LD, Kristoff J, Xu A, Del Prete GQ, Keele BF, Rao SS, ... ... Pandrea I, et al. Experimental colitis in SIV-uninfected rhesus macaques recapitulates important features of pathogenic SIV infection Nature Communications. 6. DOI: 10.1038/ncomms9020  0.389
2014 Kristoff J, Haret-Richter G, Ma D, Ribeiro RM, Xu C, Cornell E, Stock JL, He T, Mobley AD, Ross S, Trichel A, Wilson C, Tracy R, Landay A, Apetrei C, ... Pandrea I, et al. Early microbial translocation blockade reduces SIV-mediated inflammation and viral replication. The Journal of Clinical Investigation. 124: 2802-6. PMID 24837437 DOI: 10.1172/Jci75090  0.527
2014 Mandell DT, Kristoff J, Gaufin T, Gautam R, Ma D, Sandler N, Haret-Richter G, Xu C, Aamer H, Dufour J, Trichel A, Douek DC, Keele BF, Apetrei C, Pandrea I. Pathogenic features associated with increased virulence upon Simian immunodeficiency virus cross-species transmission from natural hosts. Journal of Virology. 88: 6778-92. PMID 24696477 DOI: 10.1128/Jvi.03785-13  0.604
2014 Ma D, Jasinska AJ, Feyertag F, Wijewardana V, Kristoff J, He T, Raehtz K, Schmitt CA, Jung Y, Cramer JD, Dione M, Antonio M, Tracy R, Turner T, Robertson DL, ... Pandrea I, et al. Factors associated with siman immunodeficiency virus transmission in a natural African nonhuman primate host in the wild. Journal of Virology. 88: 5687-705. PMID 24623416 DOI: 10.1128/Jvi.03606-13  0.582
2013 Wijewardana V, Kristoff J, Xu C, Ma D, Haret-Richter G, Stock JL, Policicchio BB, Mobley AD, Nusbaum R, Aamer H, Trichel A, Ribeiro RM, Apetrei C, Pandrea I. Kinetics of myeloid dendritic cell trafficking and activation: impact on progressive, nonprogressive and controlled SIV infections. Plos Pathogens. 9: e1003600. PMID 24098110 DOI: 10.1371/Journal.Ppat.1003600  0.56
2013 Ma D, Jasinska A, Kristoff J, Grobler JP, Turner T, Jung Y, Schmitt C, Raehtz K, Feyertag F, Martinez Sosa N, Wijewardana V, Burke DS, Robertson DL, Tracy R, Pandrea I, et al. SIVagm infection in wild African green monkeys from South Africa: epidemiology, natural history, and evolutionary considerations. Plos Pathogens. 9: e1003011. PMID 23349627 DOI: 10.1371/Journal.Ppat.1003011  0.526
2012 Fischer W, Apetrei C, Santiago ML, Li Y, Gautam R, Pandrea I, Shaw GM, Hahn BH, Letvin NL, Nabel GJ, Korber BT. Distinct evolutionary pressures underlie diversity in simian immunodeficiency virus and human immunodeficiency virus lineages. Journal of Virology. 86: 13217-31. PMID 23055550 DOI: 10.1128/Jvi.01862-12  0.485
2012 Apetrei C, Pandrea I, Mellors JW. Nonhuman primate models for HIV cure research. Plos Pathogens. 8: e1002892. PMID 22956905 DOI: 10.1371/Journal.Ppat.1002892  0.462
2012 Pandrea I, Cornell E, Wilson C, Ribeiro RM, Ma D, Kristoff J, Xu C, Haret-Richter GS, Trichel A, Apetrei C, Landay A, Tracy R. Coagulation biomarkers predict disease progression in SIV-infected nonhuman primates Blood. 120: 1357-1366. PMID 22653975 DOI: 10.1182/Blood-2012-03-414706  0.545
2012 Pandrea I, Parrish NF, Raehtz K, Gaufin T, Barbian HJ, Ma D, Kristoff J, Gautam R, Zhong F, Haret-Richter GS, Trichel A, Shaw GM, Hahn BH, Apetrei C. Mucosal simian immunodeficiency virus transmission in African green monkeys: susceptibility to infection is proportional to target cell availability at mucosal sites. Journal of Virology. 86: 4158-68. PMID 22318138 DOI: 10.1128/Jvi.07141-11  0.586
2012 Souquiere S, Apetrei C, Chahroudi A, Pandrea I, Silvestri G, Roques P. Reply to "Control of Simian Immunodeficiency Virus SIVmnd-1 RNA Plasma Viremia after Coinfection or Superinfection with SIVmnd-1 in SIVmnd-2-Infected Mandrills and Vice Versa". Journal of Virology. 86: 2387-8. PMID 22282337 DOI: 10.1128/Jvi.06953-11  0.442
2012 Apetrei C, Sumpter B, Souquiere S, Chahroudi A, Makuwa M, Reed P, Ribeiro RM, Pandrea I, Roques P, Silvestri G. Immunovirological analyses of chronically simian immunodeficiency virus: SIVmnd-1- and SIVmnd-2-infected mandrills (Mandrillus sphinx) Journal of Virology. 86: 1900. DOI: 10.1128/JVI.07026-11  0.432
2012 Pandrea I, Landay AL. Implications for Therapy Models of Protection Against Hiv/Siv. 81-132. DOI: 10.1016/B978-0-12-387715-4.00003-4  0.386
2011 Apetrei C, Sumpter B, Souquiere S, Chahroudi A, Makuwa M, Reed P, Ribeiro RM, Pandrea I, Roques P, Silvestri G. Immunovirological analyses of chronically simian immunodeficiency virus SIVmnd-1- and SIVmnd-2-infected mandrills (Mandrillus sphinx). Journal of Virology. 85: 13077-87. PMID 21957286 DOI: 10.1128/Jvi.05693-11  0.637
2011 Pandrea I, Gaufin T, Gautam R, Kristoff J, Mandell D, Montefiori D, Keele BF, Ribeiro RM, Veazey RS, Apetrei C. Functional cure of SIVagm infection in rhesus macaques results in complete recovery of CD4+ T cells and is reverted by CD8+ cell depletion. Plos Pathogens. 7: e1002170. PMID 21829366 DOI: 10.1371/Journal.Ppat.1002170  0.628
2011 Vinton C, Klatt NR, Harris LD, Briant JA, Sanders-Beer BE, Herbert R, Woodward R, Silvestri G, Pandrea I, Apetrei C, Hirsch VM, Brenchley JM. CD4-like immunological function by CD4- T cells in multiple natural hosts of simian immunodeficiency virus. Journal of Virology. 85: 8702-8. PMID 21715501 DOI: 10.1128/Jvi.00332-11  0.549
2011 Paiardini M, Cervasi B, Reyes-Aviles E, Micci L, Ortiz AM, Chahroudi A, Vinton C, Gordon SN, Bosinger SE, Francella N, Hallberg PL, Cramer E, Schlub T, Chan ML, Riddick NE, ... ... Pandrea I, et al. Low levels of SIV infection in sooty mangabey central memory CD⁴⁺ T cells are associated with limited CCR5 expression. Nature Medicine. 17: 830-6. PMID 21706028 DOI: 10.1038/Nm.2395  0.546
2010 Apetrei C, Gaufin T, Gautam R, Vinton C, Hirsch V, Lewis M, Brenchley J, Pandrea I. Pattern of SIVagm infection in patas monkeys suggests that host adaptation to simian immunodeficiency virus infection may result in resistance to infection and virus extinction. The Journal of Infectious Diseases. 202: S371-6. PMID 20887227 DOI: 10.1086/655970  0.634
2010 Gnanadurai CW, Pandrea I, Parrish NF, Kraus MH, Learn GH, Salazar MG, Sauermann U, Töpfer K, Gautam R, Münch J, Stahl-Hennig C, Apetrei C, Hahn BH, Kirchhoff F. Genetic identity and biological phenotype of a transmitted/founder virus representative of nonpathogenic simian immunodeficiency virus infection in African green monkeys. Journal of Virology. 84: 12245-54. PMID 20881048 DOI: 10.1128/Jvi.01603-10  0.529
2010 Gaufin T, Ribeiro RM, Gautam R, Dufour J, Mandell D, Apetrei C, Pandrea I. Experimental depletion of CD8+ cells in acutely SIVagm-infected African Green Monkeys results in increased viral replication. Retrovirology. 7: 42. PMID 20459829 DOI: 10.1186/1742-4690-7-42  0.622
2010 Pandrea I, Apetrei C. Where the wild things are: pathogenesis of SIV infection in African nonhuman primate hosts. Current Hiv/Aids Reports. 7: 28-36. PMID 20425055 DOI: 10.1007/S11904-009-0034-8  0.655
2010 Klatt NR, Shudo E, Ortiz AM, Engram JC, Paiardini M, Lawson B, Miller MD, Else J, Pandrea I, Estes JD, Apetrei C, Schmitz JE, Ribeiro RM, Perelson AS, Silvestri G. CD8+ lymphocytes control viral replication in SIVmac239-infected rhesus macaques without decreasing the lifespan of productively infected cells. Plos Pathogens. 6: e1000747. PMID 20126441 DOI: 10.1371/Journal.Ppat.1000747  0.626
2009 Sodora DL, Allan JS, Apetrei C, Brenchley JM, Douek DC, Else JG, Estes JD, Hahn BH, Hirsch VM, Kaur A, Kirchhoff F, Muller-Trutwin M, Pandrea I, Schmitz JE, Silvestri G. Toward an AIDS vaccine: lessons from natural simian immunodeficiency virus infections of African nonhuman primate hosts. Nature Medicine. 15: 861-5. PMID 19661993 DOI: 10.1038/Nm.2013  0.535
2009 Gaufin T, Pattison M, Gautam R, Stoulig C, Dufour J, MacFarland J, Mandell D, Tatum C, Marx MH, Ribeiro RM, Montefiori D, Apetrei C, Pandrea I. Effect of B-cell depletion on viral replication and clinical outcome of simian immunodeficiency virus infection in a natural host. Journal of Virology. 83: 10347-57. PMID 19656874 DOI: 10.1128/Jvi.00880-09  0.59
2009 Paiardini M, Pandrea I, Apetrei C, Silvestri G. Lessons learned from the natural hosts of HIV-related viruses. Annual Review of Medicine. 60: 485-95. PMID 19630581 DOI: 10.1146/Annurev.Med.60.041807.123753  0.583
2009 Beaumier CM, Harris LD, Goldstein S, Klatt NR, Whitted S, McGinty J, Apetrei C, Pandrea I, Hirsch VM, Brenchley JM. CD4 downregulation by memory CD4+ T cells in vivo renders African green monkeys resistant to progressive SIVagm infection. Nature Medicine. 15: 879-85. PMID 19525963 DOI: 10.1038/Nm.1970  0.546
2009 Gautam R, Gaufin T, Butler I, Gautam A, Barnes M, Mandell D, Pattison M, Tatum C, Macfarland J, Monjure C, Marx PA, Pandrea I, Apetrei C. Simian immunodeficiency virus SIVrcm, a unique CCR2-tropic virus, selectively depletes memory CD4+ T cells in pigtailed macaques through expanded coreceptor usage in vivo. Journal of Virology. 83: 7894-908. PMID 19493994 DOI: 10.1128/Jvi.00444-09  0.581
2009 Favre D, Lederer S, Kanwar B, Ma ZM, Proll S, Kasakow Z, Mold J, Swainson L, Barbour JD, Baskin CR, Palermo R, Pandrea I, Miller CJ, Katze MG, McCune JM. Critical loss of the balance between Th17 and T regulatory cell populations in pathogenic SIV infection. Plos Pathogens. 5: e1000295. PMID 19214220 DOI: 10.1371/Journal.Ppat.1000295  0.527
2009 Gaufin T, Gautam R, Kasheta M, Ribeiro R, Ribka E, Barnes M, Pattison M, Tatum C, MacFarland J, Montefiori D, Kaur A, Pandrea I, Apetrei C. Limited ability of humoral immune responses in control of viremia during infection with SIVsmmD215 strain. Blood. 113: 4250-61. PMID 19168789 DOI: 10.1182/Blood-2008-09-177741  0.483
2009 Pandrea I, Silvestri G, Apetrei C. AIDS in african nonhuman primate hosts of SIVs: a new paradigm of SIV infection. Current Hiv Research. 7: 57-72. PMID 19149555 DOI: 10.2174/157016209787048456  0.603
2009 Souquière S, Onanga R, Makuwa M, Pandrea I, Ngari P, Rouquet P, Bourry O, Kazanji M, Apetrei C, Simon F, Roques P. Simian immunodeficiency virus types 1 and 2 (SIV mnd 1 and 2) have different pathogenic potentials in rhesus macaques upon experimental cross-species transmission. The Journal of General Virology. 90: 488-99. PMID 19141460 DOI: 10.1099/Vir.0.005181-0  0.638
2008 Pandrea I, Gaufin T, Brenchley JM, Gautam R, Monjure C, Gautam A, Coleman C, Lackner AA, Ribeiro RM, Douek DC, Apetrei C. Cutting edge: Experimentally induced immune activation in natural hosts of simian immunodeficiency virus induces significant increases in viral replication and CD4+ T cell depletion. Journal of Immunology (Baltimore, Md. : 1950). 181: 6687-91. PMID 18981083 DOI: 10.4049/Jimmunol.181.10.6687  0.762
2008 Pandrea I, Sodora DL, Silvestri G, Apetrei C. Into the wild: simian immunodeficiency virus (SIV) infection in natural hosts. Trends in Immunology. 29: 419-28. PMID 18676179 DOI: 10.1016/J.It.2008.05.004  0.629
2008 Paiardini M, Frank I, Pandrea I, Apetrei C, Silvestri G. Mucosal immune dysfunction in AIDS pathogenesis. Aids Reviews. 10: 36-46. PMID 18385779  0.544
2008 Pandrea I, Onanga R, Souquiere S, Mouinga-Ondéme A, Bourry O, Makuwa M, Rouquet P, Silvestri G, Simon F, Roques P, Apetrei C. Paucity of CD4+ CCR5+ T cells may prevent transmission of simian immunodeficiency virus in natural nonhuman primate hosts by breast-feeding. Journal of Virology. 82: 5501-9. PMID 18385229 DOI: 10.1128/Jvi.02555-07  0.53
2008 Pandrea I, Ribeiro RM, Gautam R, Gaufin T, Pattison M, Barnes M, Monjure C, Stoulig C, Dufour J, Cyprian W, Silvestri G, Miller MD, Perelson AS, Apetrei C. Simian immunodeficiency virus SIVagm dynamics in African green monkeys. Journal of Virology. 82: 3713-24. PMID 18216122 DOI: 10.1128/Jvi.02402-07  0.625
2008 Gordon SN, Dunham RM, Engram JC, Estes J, Wang Z, Klatt NR, Paiardini M, Pandrea IV, Apetrei C, Sodora DL, Lee HY, Haase AT, Miller MD, Kaur A, Staprans SI, et al. Short-lived infected cells support virus replication in sooty mangabeys naturally infected with simian immunodeficiency virus: implications for AIDS pathogenesis. Journal of Virology. 82: 3725-35. PMID 18216113 DOI: 10.1128/Jvi.02408-07  0.568
2007 Coleman CA, Muller-Trutwin MC, Apetrei C, Pandrea I. T regulatory cells: aid or hindrance in the clearance of disease? Journal of Cellular and Molecular Medicine. 11: 1291-325. PMID 18205702 DOI: 10.1111/J.1582-4934.2007.00087.X  0.701
2007 Silvestri G, Paiardini M, Pandrea I, Lederman MM, Sodora DL. Understanding the benign nature of SIV infection in natural hosts. The Journal of Clinical Investigation. 117: 3148-54. PMID 17975656 DOI: 10.1172/Jci33034  0.633
2007 Pandrea IV, Gautam R, Ribeiro RM, Brenchley JM, Butler IF, Pattison M, Rasmussen T, Marx PA, Silvestri G, Lackner AA, Perelson AS, Douek DC, Veazey RS, Apetrei C. Acute loss of intestinal CD4+ T cells is not predictive of simian immunodeficiency virus virulence. Journal of Immunology (Baltimore, Md. : 1950). 179: 3035-46. PMID 17709518 DOI: 10.4049/Jimmunol.179.5.3035  0.569
2007 Gordon SN, Klatt NR, Bosinger SE, Brenchley JM, Milush JM, Engram JC, Dunham RM, Paiardini M, Klucking S, Danesh A, Strobert EA, Apetrei C, Pandrea IV, Kelvin D, Douek DC, et al. Severe depletion of mucosal CD4+ T cells in AIDS-free simian immunodeficiency virus-infected sooty mangabeys. Journal of Immunology (Baltimore, Md. : 1950). 179: 3026-34. PMID 17709517 DOI: 10.4049/Jimmunol.179.5.3026  0.61
2007 Apetrei C, Gautam R, Sumpter B, Carter AC, Gaufin T, Staprans SI, Else J, Barnes M, Cao R, Garg S, Milush JM, Sodora DL, Pandrea I, Silvestri G. Virus subtype-specific features of natural simian immunodeficiency virus SIVsmm infection in sooty mangabeys. Journal of Virology. 81: 7913-23. PMID 17507488 DOI: 10.1128/Jvi.00281-07  0.635
2007 Milush JM, Stefano-Cole K, Schmidt K, Durudas A, Pandrea I, Sodora DL. Mucosal innate immune response associated with a timely humoral immune response and slower disease progression after oral transmission of simian immunodeficiency virus to rhesus macaques. Journal of Virology. 81: 6175-86. PMID 17428863 DOI: 10.1128/Jvi.00042-07  0.468
2007 Gautam R, Carter AC, Katz N, Butler IF, Barnes M, Hasegawa A, Ratterree M, Silvestri G, Marx PA, Hirsch VM, Pandrea I, Apetrei C. In vitro characterization of primary SIVsmm isolates belonging to different lineages. In vitro growth on rhesus macaque cells is not predictive for in vivo replication in rhesus macaques. Virology. 362: 257-70. PMID 17303205 DOI: 10.1016/J.Virol.2006.12.037  0.456
2007 Butler IF, Pandrea I, Marx PA, Apetrei C. HIV genetic diversity: biological and public health consequences. Current Hiv Research. 5: 23-45. PMID 17266555 DOI: 10.2174/157016207779316297  0.37
2007 Pandrea I, Apetrei C, Gordon S, Barbercheck J, Dufour J, Bohm R, Sumpter B, Roques P, Marx PA, Hirsch VM, Kaur A, Lackner AA, Veazey RS, Silvestri G. Paucity of CD4+CCR5+ T cells is a typical feature of natural SIV hosts. Blood. 109: 1069-76. PMID 17003371 DOI: 10.1182/Blood-2006-05-024364  0.612
2006 Pandrea I, Silvestri G, Onanga R, Veazey RS, Marx PA, Hirsch V, Apetrei C. Simian immunodeficiency viruses replication dynamics in African non-human primate hosts: common patterns and species-specific differences. Journal of Medical Primatology. 35: 194-201. PMID 16872282 DOI: 10.1111/J.1600-0684.2006.00168.X  0.504
2006 Ploquin MJ, Desoutter JF, Santos PR, Pandrea I, Diop OM, Hosmalin A, Butor C, Barre-Sinoussi F, Müller-Trutwin MC. Distinct expression profiles of TGF-beta1 signaling mediators in pathogenic SIVmac and non-pathogenic SIVagm infections. Retrovirology. 3: 37. PMID 16800882 DOI: 10.1186/1742-4690-3-37  0.449
2006 Goldstein S, Brown CR, Ourmanov I, Pandrea I, Buckler-White A, Erb C, Nandi JS, Foster GJ, Autissier P, Schmitz JE, Hirsch VM. Comparison of simian immunodeficiency virus SIVagmVer replication and CD4+ T-cell dynamics in vervet and sabaeus African green monkeys. Journal of Virology. 80: 4868-77. PMID 16641278 DOI: 10.1128/Jvi.80.10.4868-4877.2006  0.614
2006 Pandrea I, Apetrei C, Dufour J, Dillon N, Barbercheck J, Metzger M, Jacquelin B, Bohm R, Marx PA, Barre-Sinoussi F, Hirsch VM, Müller-Trutwin MC, Lackner AA, Veazey RS. Simian immunodeficiency virus SIVagm.sab infection of Caribbean African green monkeys: a new model for the study of SIV pathogenesis in natural hosts. Journal of Virology. 80: 4858-67. PMID 16641277 DOI: 10.1128/Jvi.80.10.4858-4867.2006  0.613
2006 Dunham R, Pagliardini P, Gordon S, Sumpter B, Engram J, Moanna A, Paiardini M, Mandl JN, Lawson B, Garg S, McClure HM, Xu YX, Ibegbu C, Easley K, Katz N, ... Pandrea I, et al. The AIDS resistance of naturally SIV-infected sooty mangabeys is independent of cellular immunity to the virus. Blood. 108: 209-17. PMID 16522814 DOI: 10.1182/Blood-2005-12-4897  0.625
2005 Apetrei C, Kaur A, Lerche NW, Metzger M, Pandrea I, Hardcastle J, Falkenstein S, Bohm R, Koehler J, Traina-Dorge V, Williams T, Staprans S, Plauche G, Veazey RS, McClure H, et al. Molecular epidemiology of simian immunodeficiency virus SIVsm in U.S. primate centers unravels the origin of SIVmac and SIVstm. Journal of Virology. 79: 8991-9005. PMID 15994793 DOI: 10.1128/Jvi.79.14.8991-9005.2005  0.387
2005 Pandrea I, Kornfeld C, Ploquin MJY, Apetrei C, Faye A, Rouquet P, Roques P, Simon F, Barré-Sinoussi F, Müller-Trutwin MC, Diop OM. Impact of viral factors on very early in vivo replication profiles in simian immunodeficiency virus SIVagm-infected African green monkeys Journal of Virology. 79: 6249-6259. PMID 15858009 DOI: 10.1128/Jvi.79.10.6249-6259.2005  0.545
2005 Chandhasin C, Coan PN, Pandrea I, Grant CK, Lobelle-Rich PA, Puetter A, Levy LS. Unique long terminal repeat and surface glycoprotein gene sequences of feline leukemia virus as determinants of disease outcome. Journal of Virology. 79: 5278-87. PMID 15827142 DOI: 10.1128/Jvi.79.9.5278-5287.2005  0.339
2005 Kornfeld C, Ploquin MJY, Pandrea I, Faye A, Onanga R, Apetrei C, Poaty-Mavoungou V, Rouquet P, Estaquier J, Mortara L, Desoutter JF, Butor C, Le Grand R, Roques P, Simon F, et al. Antiinflammatory profiles during primary SIV infection in African green monkeys are associated with protection against AIDS Journal of Clinical Investigation. 115: 1082-1091. PMID 15761496 DOI: 10.1172/Jci23006  0.547
2004 Apetrei C, Gormus B, Pandrea I, Metzger M, ten Haaft P, Martin LN, Bohm R, Alvarez X, Koopman G, Murphey-Corb M, Veazey RS, Lackner AA, Baskin G, Heeney J, Marx PA. Direct inoculation of simian immunodeficiency virus from sooty mangabeys in black mangabeys (Lophocebus aterrimus): first evidence of AIDS in a heterologous African species and different pathologic outcomes of experimental infection. Journal of Virology. 78: 11506-18. PMID 15479792 DOI: 10.1128/Jvi.78.21.11506-11518.2004  0.52
2004 Ling B, Apetrei C, Pandrea I, Veazey RS, Lackner AA, Gormus B, Marx PA. Classic AIDS in a sooty mangabey after an 18-year natural infection. Journal of Virology. 78: 8902-8. PMID 15280498 DOI: 10.1128/Jvi.78.16.8902-8908.2004  0.548
2003 Apetrei C, Descamps D, Collin G, Robertson DL, Pandrea I, Groza P, Prisecariu L, Teodorescu I, Luca V, Brun-Vézinet F. HIV type 1 diversity in northeastern Romania in 200-2001 based on phylogenic analysis of pol sequences from patient failing antiretroviral therapy. Aids Research and Human Retroviruses. 19: 1155-1161. PMID 14714572 DOI: 10.1089/088922203771881266  0.395
2003 Pandrea I, Onanga R, Kornfeld C, Rouquet P, Bourry O, Clifford S, Telfer PT, Abernethy K, White LT, Ngari P, Müller-Trutwin M, Roques P, Marx PA, Simon F, Apetrei C. High levels of SIVmnd-1 replication in chronically infected Mandrillus sphinx. Virology. 317: 119-27. PMID 14675630 DOI: 10.1016/J.Virol.2003.08.015  0.596
2003 Veazey RS, Klasse PJ, Ketas TJ, Reeves JD, Piatak M, Kunstman K, Kuhmann SE, Marx PA, Lifson JD, Dufour J, Mefford M, Pandrea I, Wolinsky SM, Doms RW, DeMartino JA, et al. Use of a small molecule CCR5 inhibitor in macaques to treat simian immunodeficiency virus infection or prevent simian-human immunodeficiency virus infection. The Journal of Experimental Medicine. 198: 1551-62. PMID 14623909 DOI: 10.1084/Jem.20031266  0.562
2003 Lifson JD, Piatak M, Cline AN, Rossio JL, Purcell J, Pandrea I, Bischofberger N, Blanchard J, Veazey RS. Transient early post-inoculation anti-retroviral treatment facilitates controlled infection with sparing of CD4+ T cells in gut-associated lymphoid tissues in SIV mac239-infected rhesus macaques, but not resistance to rechallenge Journal of Medical Primatology. 32: 201-210. PMID 14498980 DOI: 10.1034/J.1600-0684.2003.00026.X  0.588
2003 Veazey RS, Lifson JD, Schmitz JE, Kuroda MJ, Piatak M, Pandrea I, Purcell J, Bohm R, Blanchard J, Williams KC, Lackner AA. Dynamics of Simian immunodeficiency virus-specific cytotoxic T-cell responses in tissues. Journal of Medical Primatology. 32: 194-200. PMID 14498979 DOI: 10.1034/J.1600-0684.2003.00025.X  0.529
2003 Veazey RS, Lifson JD, Pandrea I, Purcell J, Piatak M, Lackner AA. Simian immunodeficiency virus infection in neonatal macaques. Journal of Virology. 77: 8783-92. PMID 12885897 DOI: 10.1128/Jvi.77.16.8783-8792.2003  0.577
2003 Veazey R, Ling B, Pandrea I, McClure H, Lackner A, Marx P. Decreased CCR5 expression on CD4+ T cells of SIV-infected sooty mangabeys. Aids Research and Human Retroviruses. 19: 227-33. PMID 12689415 DOI: 10.1089/088922203763315731  0.621
2002 Pandrea I, Robertson DL, Onanga R, Gao F, Makuwa M, Ngari P, Bedjabaga I, Roques P, Simon F, Apetrei C. Analysis of partial pol and env sequences indicates a high prevalence of HIV type 1 recombinant strains circulating in Gabon. Aids Research and Human Retroviruses. 18: 1103-16. PMID 12396449 DOI: 10.1089/088922202320567842  0.303
2002 Onanga R, Kornfeld C, Pandrea I, Estaquier J, Souquière S, Rouquet P, Poaty Mavoungou VP, Bourry O, M'Boup S, Barré-Sinoussi F, Simon F, Apetrei C, Roques P, Müller-Trutwin MC. High levels of viral replication contrast with only transient changes in CD4+ and CD8+ cell numbers during the early phase of experimental infection with simian immunodeficiency virus SIVmnd-1 in Mandrillus sphinx Journal of Virology. 76: 10256-10263. PMID 12239301 DOI: 10.1128/Jvi.76.20.10256-10263.2002  0.585
2001 Pandrea I, Onanga R, Rouquet P, Bourry O, Ngari P, Wickings EJ, Roques P, Apetrei C. Chronic SIV infection ultimately causes immunodeficiency in African non-human primates [3] Aids. 15: 2461-2462. PMID 11826852 DOI: 10.1097/00002030-200112070-00019  0.457
2001 Pandrea I, Brun-Vézinet F, Apetrei C, Descamps D, Collin G, Robertson DL, Damond F, Dimitrienco V, Gheorghita S, Pecec M, Simon F. HIV type 1 genetic diversity and genotypic drug susceptibility in the Republic of Moldova Aids Research and Human Retroviruses. 17: 1297-1304. PMID 11559431 DOI: 10.1089/088922201750461375  0.368
2001 Simon F, Lecu A, Telfer PT, Pandrea I, Plantier JC, Barré-Sinoussi F, Roques P, Müller-Trutwin MC, Apetrei C, Souquière S, Damond F, Kfutwah A, Makuwa M, Leroy E, Rouquet P, et al. Synthetic peptide strategy for the detection of and discrimination among highly divergent primate lentiviruses Aids Research and Human Retroviruses. 17: 937-952. PMID 11461679 DOI: 10.1089/088922201750290050  0.366
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