E. Ron de Kloet - Publications

Affiliations: 
Medical Pharmacology Leiden University, Leiden, Netherlands 
Area:
biology of stress
Website:
https://www.knaw.nl/nl/leden/experten/4370

256 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Daskalakis NP, Meijer OC, de Kloet ER. Mineralocorticoid receptor and glucocorticoid receptor work alone and together in cell-type-specific manner: Implications for resilience prediction and targeted therapy. Neurobiology of Stress. 18: 100455. PMID 35601687 DOI: 10.1016/j.ynstr.2022.100455  0.736
2018 de Kloet ER, de Kloet SF, de Kloet CS, de Kloet AD. Top-down and bottom-up control of stress-coping. Journal of Neuroendocrinology. e12675. PMID 30578574 DOI: 10.1111/jne.12675  0.331
2018 Dalm S, Karssen AM, Meijer OC, Belanoff JK, de Kloet ER. Resetting the Stress System with a Mifepristone Challenge. Cellular and Molecular Neurobiology. PMID 30173378 DOI: 10.1007/S10571-018-0614-5  0.611
2018 Brocca ME, Pietranera L, de Kloet ER, De Nicola AF. Mineralocorticoid Receptors, Neuroinflammation and Hypertensive Encephalopathy. Cellular and Molecular Neurobiology. 39: 483-492. PMID 30117098 DOI: 10.1007/s10571-018-0610-9  0.642
2017 Joëls M, de Kloet ER. 30 YEARS OF THE MINERALOCORTICOID RECEPTOR: The brain mineralocorticoid receptor: a saga in three episodes. The Journal of Endocrinology. 234: T49-T66. PMID 28634266 DOI: 10.1530/JOE-16-0660  0.801
2017 Brocca ME, Pietranera L, Meyer M, Lima A, Roig P, de Kloet ER, De Nicola AF. Mineralocorticoid receptor associates with pro-inflammatory bias in hippocampus of spontaneously hypertensive rats. Journal of Neuroendocrinology. PMID 28523794 DOI: 10.1111/jne.12489  0.631
2017 van Weert LT, Buurstede JC, Mahfouz A, Braakhuis PS, Polman JA, Sips HC, Roozendaal B, Balog J, de Kloet ER, Datson NA, Meijer OC. NeuroD factors discriminate mineralocorticoid from glucocorticoid receptor DNA binding in the male rat brain. Endocrinology. PMID 28324065 DOI: 10.1210/En.2016-1422  0.526
2017 Meijer OC, de Kloet ER. A Refill for the Brain Mineralocorticoid Receptor: The Benefit of Cortisol Add-On to Dexamethasone Therapy. Endocrinology. 158: 448-454. PMID 27967238 DOI: 10.1210/En.2016-1495  0.536
2016 Oster H, Challet E, Ott V, Arvat E, de Kloet ER, Dijk DJ, Lightman S, Vgontzas A, Van Cauter E. The functional and clinical significance of the 24-h rhythm of circulating glucocorticoids. Endocrine Reviews. er20151080. PMID 27749086 DOI: 10.1210/Er.2015-1080  0.529
2016 de Kloet ER, Otte C, Kumsta R, Kok L, Hillegers MH, Hasselmann H, Kliegel D, Joëls M. STRESS and DEPRESSION a crucial role of the mineralocorticoid receptor. Journal of Neuroendocrinology. PMID 26970338 DOI: 10.1111/jne.12379  0.783
2015 Daskalakis NP, De Kloet ER, Yehuda R, Malaspina D, Kranz TM. Early Life Stress Effects on Glucocorticoid-BDNF Interplay in the Hippocampus. Frontiers in Molecular Neuroscience. 8: 68. PMID 26635521 DOI: 10.3389/Fnmol.2015.00068  0.703
2014 Daskalakis NP, Enthoven L, Schoonheere E, de Kloet ER, Oitzl MS. Immediate Effects of Maternal Deprivation on the (Re)Activity of the HPA-Axis Differ in CD1 and C57Bl/6J Mouse Pups. Frontiers in Endocrinology. 5: 190. PMID 25414695 DOI: 10.3389/Fendo.2014.00190  0.813
2014 Judd LL, Schettler PJ, Brown ES, Wolkowitz OM, Sternberg EM, Bender BG, Bulloch K, Cidlowski JA, de Kloet ER, Fardet L, Joëls M, Leung DY, McEwen BS, Roozendaal B, Van Rossum EF, et al. Adverse consequences of glucocorticoid medication: psychological, cognitive, and behavioral effects. The American Journal of Psychiatry. 171: 1045-51. PMID 25272344 DOI: 10.1176/Appi.Ajp.2014.13091264  0.443
2014 de Kloet ER, Claessens SE, Kentrop J. Context modulates outcome of perinatal glucocorticoid action in the brain. Frontiers in Endocrinology. 5: 100. PMID 25071717 DOI: 10.3389/Fendo.2014.00100  0.808
2014 de Kloet ER. From receptor balance to rational glucocorticoid therapy. Endocrinology. 155: 2754-69. PMID 24828611 DOI: 10.1210/en.2014-1048  0.37
2014 Ter Horst JP, van der Mark M, Kentrop J, Arp M, van der Veen R, de Kloet ER, Oitzl MS. Deletion of the forebrain mineralocorticoid receptor impairs social discrimination and decision-making in male, but not in female mice. Frontiers in Behavioral Neuroscience. 8: 26. PMID 24567706 DOI: 10.3389/Fnbeh.2014.00026  0.693
2014 Meyer M, Gonzalez Deniselle MC, Hunt H, de Kloet ER, De Nicola AF. The selective glucocorticoid receptor modulator CORT108297 restores faulty hippocampal parameters in Wobbler and corticosterone-treated mice. The Journal of Steroid Biochemistry and Molecular Biology. 143: 40-8. PMID 24565565 DOI: 10.1016/j.jsbmb.2014.02.007  0.664
2014 Souza RR, Dal Bó S, de Kloet ER, Oitzl MS, Carobrez AP. Paradoxical mineralocorticoid receptor-mediated effect in fear memory encoding and expression of rats submitted to an olfactory fear conditioning task. Neuropharmacology. 79: 201-11. PMID 24296155 DOI: 10.1016/J.Neuropharm.2013.11.017  0.806
2014 Daskalakis NP, Diamantopoulou A, Claessens SE, Remmers E, Tjälve M, Oitzl MS, Champagne DL, de Kloet ER. Early experience of a novel-environment in isolation primes a fearful phenotype characterized by persistent amygdala activation. Psychoneuroendocrinology. 39: 39-57. PMID 24275003 DOI: 10.1016/J.Psyneuen.2013.09.021  0.809
2013 de Kloet ER. Lifetime achievement from a brain-adrenal perspective: on the CRF-urocortin-glucocorticoid balance. Journal of Chemical Neuroanatomy. 54: 42-9. PMID 24161414 DOI: 10.1016/j.jchemneu.2013.10.003  0.335
2013 Kruk MR, Haller J, Meelis W, de Kloet ER. Mineralocorticoid receptor blockade during a rat's first violent encounter inhibits its subsequent propensity for violence. Behavioral Neuroscience. 127: 505-14. PMID 23895062 DOI: 10.1037/A0033553  0.334
2013 Daskalakis NP, Bagot RC, Parker KJ, Vinkers CH, de Kloet ER. The three-hit concept of vulnerability and resilience: toward understanding adaptation to early-life adversity outcome. Psychoneuroendocrinology. 38: 1858-73. PMID 23838101 DOI: 10.1016/J.Psyneuen.2013.06.008  0.593
2013 Ter Horst JP, Kentrop J, Arp M, Hubens CJ, de Kloet ER, Oitzl MS. Spatial learning of female mice: a role of the mineralocorticoid receptor during stress and the estrous cycle. Frontiers in Behavioral Neuroscience. 7: 56. PMID 23754993 DOI: 10.3389/Fnbeh.2013.00056  0.732
2013 Datson NA, van den Oever JM, Korobko OB, Magarinos AM, de Kloet ER, McEwen BS. Previous history of chronic stress changes the transcriptional response to glucocorticoid challenge in the dentate gyrus region of the male rat hippocampus. Endocrinology. 154: 3261-72. PMID 23633533 DOI: 10.1210/en.2012-2233  0.574
2013 Zalachoras I, Houtman R, Atucha E, Devos R, Tijssen AM, Hu P, Lockey PM, Datson NA, Belanoff JK, Lucassen PJ, Joëls M, de Kloet ER, Roozendaal B, Hunt H, Meijer OC. Differential targeting of brain stress circuits with a selective glucocorticoid receptor modulator. Proceedings of the National Academy of Sciences of the United States of America. 110: 7910-5. PMID 23613579 DOI: 10.1073/Pnas.1219411110  0.826
2013 ter Horst JP, Kentrop J, de Kloet ER, Oitzl MS. Stress and estrous cycle affect strategy but not performance of female C57BL/6J mice. Behavioural Brain Research. 241: 92-5. PMID 23219839 DOI: 10.1016/J.Bbr.2012.11.040  0.714
2013 Harris AP, Holmes MC, de Kloet ER, Chapman KE, Seckl JR. Mineralocorticoid and glucocorticoid receptor balance in control of HPA axis and behaviour. Psychoneuroendocrinology. 38: 648-58. PMID 22980941 DOI: 10.1016/j.psyneuen.2012.08.007  0.352
2013 Fitzsimons CP, van Hooijdonk LW, Schouten M, Zalachoras I, Brinks V, Zheng T, Schouten TG, Saaltink DJ, Dijkmans T, Steindler DA, Verhaagen J, Verbeek FJ, Lucassen PJ, de Kloet ER, Meijer OC, et al. Knockdown of the glucocorticoid receptor alters functional integration of newborn neurons in the adult hippocampus and impairs fear-motivated behavior. Molecular Psychiatry. 18: 993-1005. PMID 22925833 DOI: 10.1038/Mp.2012.123  0.8
2012 Claessens SE, Belanoff JK, Kanatsou S, Lucassen PJ, Champagne DL, de Kloet ER. Acute effects of neonatal dexamethasone treatment on proliferation and astrocyte immunoreactivity in hippocampus and corpus callosum: towards a rescue strategy. Brain Research. 1482: 1-12. PMID 22985498 DOI: 10.1016/J.Brainres.2012.08.017  0.803
2012 Sarabdjitsingh RA, Kofink D, Karst H, de Kloet ER, Joëls M. Stress-induced enhancement of mouse amygdalar synaptic plasticity depends on glucocorticoid and ß-adrenergic activity. Plos One. 7: e42143. PMID 22900007 DOI: 10.1371/journal.pone.0042143  0.827
2012 Claessens SE, Daskalakis NP, Oitzl MS, de Kloet ER. Early handling modulates outcome of neonatal dexamethasone exposure. Hormones and Behavior. 62: 433-41. PMID 22892314 DOI: 10.1016/J.Yhbeh.2012.07.011  0.803
2012 Ter Horst JP, Carobrez AP, van der Mark MH, de Kloet ER, Oitzl MS. Sex differences in fear memory and extinction of mice with forebrain-specific disruption of the mineralocorticoid receptor. The European Journal of Neuroscience. 36: 3096-102. PMID 22831399 DOI: 10.1111/J.1460-9568.2012.08237.X  0.707
2012 Polman JA, Hunter RG, Speksnijder N, van den Oever JM, Korobko OB, McEwen BS, de Kloet ER, Datson NA. Glucocorticoids modulate the mTOR pathway in the hippocampus: differential effects depending on stress history. Endocrinology. 153: 4317-27. PMID 22778218 DOI: 10.1210/en.2012-1255  0.718
2012 Dalm S, de Kloet ER, Oitzl MS. Post-training reward partially restores chronic stress induced effects in mice. Plos One. 7: e39033. PMID 22745700 DOI: 10.1371/Journal.Pone.0039033  0.74
2012 ter Horst JP, van der Mark MH, Arp M, Berger S, de Kloet ER, Oitzl MS. Stress or no stress: mineralocorticoid receptors in the forebrain regulate behavioral adaptation. Neurobiology of Learning and Memory. 98: 33-40. PMID 22543192 DOI: 10.1016/J.Nlm.2012.04.006  0.748
2012 Daskalakis NP, Oitzl MS, Schächinger H, Champagne DL, de Kloet ER. Testing the cumulative stress and mismatch hypotheses of psychopathology in a rat model of early-life adversity. Physiology & Behavior. 106: 707-21. PMID 22306534 DOI: 10.1016/J.Physbeh.2012.01.015  0.815
2012 ter Horst JP, de Kloet ER, Schächinger H, Oitzl MS. Relevance of stress and female sex hormones for emotion and cognition. Cellular and Molecular Neurobiology. 32: 725-35. PMID 22113371 DOI: 10.1007/S10571-011-9774-2  0.697
2012 Sarabdjitsingh RA, Joëls M, de Kloet ER. Glucocorticoid pulsatility and rapid corticosteroid actions in the central stress response. Physiology & Behavior. 106: 73-80. PMID 21971364 DOI: 10.1016/j.physbeh.2011.09.017  0.817
2012 Datson NA, Speksnijder N, Mayer JL, Steenbergen PJ, Korobko O, Goeman J, de Kloet ER, Joëls M, Lucassen PJ. The transcriptional response to chronic stress and glucocorticoid receptor blockade in the hippocampal dentate gyrus. Hippocampus. 22: 359-71. PMID 21184481 DOI: 10.1002/Hipo.20905  0.333
2012 Sarabdjitsingh RA, Conway-Campbell BL, Leggett JD, Waite EJ, Meijer OC, De Kloet ER, Lightman SL. Stress responsiveness varies over the ultradian glucocorticoid cycle in a brain-region-specific manner (Endocrinology (2010) 151 (5369-5379) DOI: 10.1210/en.2010-0832) Endocrinology. 153: 6159. DOI: 10.1210/en.2012-1997  0.811
2011 Daskalakis NP, Claessens SE, Laboyrie JJ, Enthoven L, Oitzl MS, Champagne DL, de Kloet ER. The newborn rat's stress system readily habituates to repeated and prolonged maternal separation, while continuing to respond to stressors in context dependent fashion. Hormones and Behavior. 60: 165-76. PMID 21570400 DOI: 10.1016/J.Yhbeh.2011.04.003  0.804
2011 Llorente R, Miguel-Blanco C, Aisa B, Lachize S, Borcel E, Meijer OC, Ramirez MJ, De Kloet ER, Viveros MP. Long term sex-dependent psychoneuroendocrine effects of maternal deprivation and juvenile unpredictable stress in rats. Journal of Neuroendocrinology. 23: 329-44. PMID 21219484 DOI: 10.1111/J.1365-2826.2011.02109.X  0.577
2011 Claessens SE, Daskalakis NP, van der Veen R, Oitzl MS, de Kloet ER, Champagne DL. Development of individual differences in stress responsiveness: an overview of factors mediating the outcome of early life experiences. Psychopharmacology. 214: 141-54. PMID 21165737 DOI: 10.1007/S00213-010-2118-Y  0.799
2011 Schenk GJ, Vreugdenhil E, Hubens CJ, Veldhuisen B, de Kloet ER, Oitzl MS. Hippocampal CARP over-expression solidifies consolidation of contextual fear memories. Physiology & Behavior. 102: 323-31. PMID 21130104 DOI: 10.1016/J.Physbeh.2010.11.024  0.704
2011 van Leeuwen N, Bellingrath S, de Kloet ER, Zitman FG, DeRijk RH, Kudielka BM, Wüst S. Human mineralocorticoid receptor (MR) gene haplotypes modulate MR expression and transactivation: implication for the stress response. Psychoneuroendocrinology. 36: 699-709. PMID 21095064 DOI: 10.1016/j.psyneuen.2010.10.003  0.318
2011 Lucassen PJ, Fitzsimons CP, Vreugdenhil E, Hu P, Oomen C, Revsin Y, Joëls M, de Kloet ER. Regulation of Structural Plasticity and Neurogenesis during Stress and Diabetes; Protective Effects of Glucocorticoid Receptor Antagonists Hormones in Neurodegeneration, Neuroprotection, and Neurogenesis. 103-120. DOI: 10.1002/9783527633968.ch6  0.803
2011 de Kloet ER, Derijk RH, Meijer OC. Corticosteroid Receptor Involvement in the Stress Response The Handbook of Stress: Neuropsychological Effects On the Brain. 47-75. DOI: 10.1002/9781118083222.ch3  0.579
2010 Sarabdjitsingh RA, Conway-Campbell BL, Leggett JD, Waite EJ, Meijer OC, de Kloet ER, Lightman SL. Stress responsiveness varies over the ultradian glucocorticoid cycle in a brain-region-specific manner. Endocrinology. 151: 5369-79. PMID 20861228 DOI: 10.1210/En.2010-0832  0.818
2010 Schenk GJ, Veldhuisen B, Wedemeier O, McGown CC, Schouten TG, Oitzl M, de Kloet ER, Vreugdenhil E. Over-expression of δC-DCLK-short in mouse brain results in a more anxious behavioral phenotype. Physiology & Behavior. 101: 541-8. PMID 20705078 DOI: 10.1016/J.Physbeh.2010.08.002  0.699
2010 Conway-Campbell BL, Sarabdjitsingh RA, McKenna MA, Pooley JR, Kershaw YM, Meijer OC, De Kloet ER, Lightman SL. Glucocorticoid ultradian rhythmicity directs cyclical gene pulsing of the clock gene period 1 in rat hippocampus. Journal of Neuroendocrinology. 22: 1093-100. PMID 20649850 DOI: 10.1111/J.1365-2826.2010.02051.X  0.801
2010 Schwabe L, Schächinger H, de Kloet ER, Oitzl MS. Stress impairs spatial but not early stimulus-response learning. Behavioural Brain Research. 213: 50-5. PMID 20420857 DOI: 10.1016/J.Bbr.2010.04.029  0.707
2010 Sarabdjitsingh RA, Spiga F, Oitzl MS, Kershaw Y, Meijer OC, Lightman SL, de Kloet ER. Recovery from disrupted ultradian glucocorticoid rhythmicity reveals a dissociation between hormonal and behavioural stress responsiveness. Journal of Neuroendocrinology. 22: 862-71. PMID 20403086 DOI: 10.1111/J.1365-2826.2010.02004.X  0.82
2010 Sarabdjitsingh RA, Meijer OC, de Kloet ER. Specificity of glucocorticoid receptor primary antibodies for analysis of receptor localization patterns in cultured cells and rat hippocampus. Brain Research. 1331: 1-11. PMID 20307510 DOI: 10.1016/J.Brainres.2010.03.052  0.789
2010 Berry A, Carnevale D, Giorgio M, Pelicci PG, de Kloet ER, Alleva E, Minghetti L, Cirulli F. Greater resistance to inflammation at adulthood could contribute to extended life span of p66(Shc-/-) mice. Experimental Gerontology. 45: 343-50. PMID 20085805 DOI: 10.1016/J.Exger.2010.01.010  0.551
2010 Sarabdjitsingh RA, Isenia S, Polman A, Mijalkovic J, Lachize S, Datson N, de Kloet ER, Meijer OC. Disrupted corticosterone pulsatile patterns attenuate responsiveness to glucocorticoid signaling in rat brain. Endocrinology. 151: 1177-86. PMID 20080870 DOI: 10.1210/En.2009-1119  0.828
2010 Enthoven L, Schmidt MV, Cheung YH, van der Mark MH, de Kloet ER, Oitzl MS. Ontogeny of the HPA axis of the CD1 mouse following 24 h maternal deprivation at pnd 3. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 28: 217-24. PMID 19897026 DOI: 10.1016/J.Ijdevneu.2009.10.006  0.836
2010 de Kloet ER. From vasotocin to stress and cognition. European Journal of Pharmacology. 626: 18-26. PMID 19837060 DOI: 10.1016/j.ejphar.2009.10.017  0.357
2010 Oitzl MS, Champagne DL, van der Veen R, de Kloet ER. Brain development under stress: hypotheses of glucocorticoid actions revisited. Neuroscience and Biobehavioral Reviews. 34: 853-66. PMID 19631685 DOI: 10.1016/J.Neubiorev.2009.07.006  0.831
2010 Schwabe L, Schächinger H, de Kloet ER, Oitzl MS. Corticosteroids operate as a switch between memory systems. Journal of Cognitive Neuroscience. 22: 1362-72. PMID 19445601 DOI: 10.1162/Jocn.2009.21278  0.716
2009 Daskalakis NP, Kaperoni M, Koros C, de Kloet ER, Kitraki E. Environmental and tactile stimulation modulates the neonatal handling effect on adult rat spatial memory. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 27: 747-55. PMID 19720127 DOI: 10.1016/J.Ijdevneu.2009.08.013  0.579
2009 de Kloet ER. [Stress: a neurobiological perspective]. Tijdschrift Voor Psychiatrie. 51: 541-50. PMID 19658066  0.333
2009 Revsin Y, de Kloet ER. When glucocorticoids change from protective to harmful. Lessons from a type 1 diabetes animal model. Medicina. 69: 353-8. PMID 19622487  0.822
2009 Brittijn SA, Duivesteijn SJ, Belmamoune M, Bertens LF, Bitter W, de Bruijn JD, Champagne DL, Cuppen E, Flik G, Vandenbroucke-Grauls CM, Janssen RA, de Jong IM, de Kloet ER, Kros A, Meijer AH, et al. Zebrafish development and regeneration: new tools for biomedical research. The International Journal of Developmental Biology. 53: 835-50. PMID 19557689 DOI: 10.1387/Ijdb.082615Sb  0.69
2009 Brinks V, Berger S, Gass P, de Kloet ER, Oitzl MS. Mineralocorticoid receptors in control of emotional arousal and fear memory. Hormones and Behavior. 56: 232-8. PMID 19447109 DOI: 10.1016/J.Yhbeh.2009.05.003  0.742
2009 Lachize S, Apostolakis EM, van der Laan S, Tijssen AM, Xu J, de Kloet ER, Meijer OC. Steroid receptor coactivator-1 is necessary for regulation of corticotropin-releasing hormone by chronic stress and glucocorticoids. Proceedings of the National Academy of Sciences of the United States of America. 106: 8038-42. PMID 19416907 DOI: 10.1073/Pnas.0812062106  0.612
2009 de Kloet ER, Fitzsimons CP, Datson NA, Meijer OC, Vreugdenhil E. Glucocorticoid signaling and stress-related limbic susceptibility pathway: about receptors, transcription machinery and microRNA. Brain Research. 1293: 129-41. PMID 19332027 DOI: 10.1016/J.Brainres.2009.03.039  0.59
2009 van der Laan S, de Kloet ER, Meijer OC. Timing is critical for effective glucocorticoid receptor mediated repression of the cAMP-induced CRH gene. Plos One. 4: e4327. PMID 19177170 DOI: 10.1371/Journal.Pone.0004327  0.534
2009 Brinks V, de Kloet ER, Oitzl MS. Corticosterone facilitates extinction of fear memory in BALB/c mice but strengthens cue related fear in C57BL/6 mice. Experimental Neurology. 216: 375-82. PMID 19162011 DOI: 10.1016/J.Expneurol.2008.12.011  0.697
2009 Vreugdenhil E, Verissimo CS, Mariman R, Kamphorst JT, Barbosa JS, Zweers T, Champagne DL, Schouten T, Meijer OC, de Kloet ER, Fitzsimons CP. MicroRNA 18 and 124a down-regulate the glucocorticoid receptor: implications for glucocorticoid responsiveness in the brain. Endocrinology. 150: 2220-8. PMID 19131573 DOI: 10.1210/En.2008-1335  0.739
2009 Champagne DL, de Kloet ER, Joëls M. Fundamental aspects of the impact of glucocorticoids on the (immature) brain. Seminars in Fetal & Neonatal Medicine. 14: 136-42. PMID 19073374 DOI: 10.1016/J.Siny.2008.11.006  0.714
2009 Sarabdjitsingh RA, Meijer OC, Schaaf MJ, de Kloet ER. Subregion-specific differences in translocation patterns of mineralocorticoid and glucocorticoid receptors in rat hippocampus. Brain Research. 1249: 43-53. PMID 19007760 DOI: 10.1016/J.Brainres.2008.10.048  0.828
2009 Revsin Y, Rekers NV, Louwe MC, Saravia FE, De Nicola AF, de Kloet ER, Oitzl MS. Glucocorticoid receptor blockade normalizes hippocampal alterations and cognitive impairment in streptozotocin-induced type 1 diabetes mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 747-58. PMID 18784648 DOI: 10.1038/Npp.2008.136  0.798
2008 van der Laan S, Sarabdjitsingh RA, Van Batenburg MF, Lachize SB, Li H, Dijkmans TF, Vreugdenhil E, de Kloet ER, Meijer OC. Chromatin immunoprecipitation scanning identifies glucocorticoid receptor binding regions in the proximal promoter of a ubiquitously expressed glucocorticoid target gene in brain. Journal of Neurochemistry. 106: 2515-23. PMID 18643788 DOI: 10.1111/J.1471-4159.2008.05575.X  0.807
2008 Enthoven L, Oitzl MS, Koning N, van der Mark M, de Kloet ER. Hypothalamic-pituitary-adrenal axis activity of newborn mice rapidly desensitizes to repeated maternal absence but becomes highly responsive to novelty. Endocrinology. 149: 6366-77. PMID 18635659 DOI: 10.1210/En.2008-0238  0.824
2008 de Kloet ER, Sarabdjitsingh RA. Everything has rhythm: focus on glucocorticoid pulsatility. Endocrinology. 149: 3241-3. PMID 18586914 DOI: 10.1210/en.2008-0471  0.783
2008 Champagne DL, Bagot RC, van Hasselt F, Ramakers G, Meaney MJ, de Kloet ER, Joëls M, Krugers H. Maternal care and hippocampal plasticity: evidence for experience-dependent structural plasticity, altered synaptic functioning, and differential responsiveness to glucocorticoids and stress. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 6037-45. PMID 18524909 DOI: 10.1523/Jneurosci.0526-08.2008  0.813
2008 de Kloet ER. About stress hormones and resilience to psychopathology. Journal of Neuroendocrinology. 20: 885-92. PMID 18513208 DOI: 10.1111/j.1365-2826.2008.01707.x  0.323
2008 Enthoven L, de Kloet ER, Oitzl MS. Differential development of stress system (re)activity at weaning dependent on time of disruption of maternal care. Brain Research. 1217: 62-9. PMID 18501879 DOI: 10.1016/J.Brainres.2008.04.009  0.831
2008 Revsin Y, van Wijk D, Saravia FE, Oitzl MS, De Nicola AF, de Kloet ER. Adrenal hypersensitivity precedes chronic hypercorticism in streptozotocin-induced diabetes mice. Endocrinology. 149: 3531-9. PMID 18420743 DOI: 10.1210/En.2007-1340  0.793
2008 de Kloet ER, de Jong IE, Oitzl MS. Neuropharmacology of glucocorticoids: focus on emotion, cognition and cocaine. European Journal of Pharmacology. 585: 473-82. PMID 18417120 DOI: 10.1016/J.Ejphar.2008.03.011  0.717
2008 Dalm S, Brinks V, van der Mark MH, de Kloet ER, Oitzl MS. Non-invasive stress-free application of glucocorticoid ligands in mice. Journal of Neuroscience Methods. 170: 77-84. PMID 18308401 DOI: 10.1016/J.Jneumeth.2007.12.021  0.725
2008 Datson NA, Morsink MC, Meijer OC, de Kloet ER. Central corticosteroid actions: Search for gene targets. European Journal of Pharmacology. 583: 272-89. PMID 18295201 DOI: 10.1016/J.Ejphar.2007.11.070  0.541
2008 de Kloet ER, Karst H, Joëls M. Corticosteroid hormones in the central stress response: quick-and-slow. Frontiers in Neuroendocrinology. 29: 268-72. PMID 18067954 DOI: 10.1016/j.yfrne.2007.10.002  0.327
2008 Joëls M, Karst H, DeRijk R, de Kloet ER. The coming out of the brain mineralocorticoid receptor. Trends in Neurosciences. 31: 1-7. PMID 18063498 DOI: 10.1016/j.tins.2007.10.005  0.327
2008 Brinks V, de Kloet ER, Oitzl MS. Strain specific fear behaviour and glucocorticoid response to aversive events: modelling PTSD in mice. Progress in Brain Research. 167: 257-61. PMID 18037021 DOI: 10.1016/S0079-6123(07)67019-8  0.701
2008 van der Laan S, Lachize SB, Vreugdenhil E, de Kloet ER, Meijer OC. Nuclear receptor coregulators differentially modulate induction and glucocorticoid receptor-mediated repression of the corticotropin-releasing hormone gene. Endocrinology. 149: 725-32. PMID 18006628 DOI: 10.1210/En.2007-1234  0.567
2008 de Kloet ER, Han F, Meijer OC. From the stalk to down under about brain glucocorticoid receptors, stress and development. Neurochemical Research. 33: 637-42. PMID 17973189 DOI: 10.1007/S11064-007-9520-9  0.589
2008 Enthoven L, de Kloet ER, Oitzl MS. Effects of maternal deprivation of CD1 mice on performance in the water maze and swim stress. Behavioural Brain Research. 187: 195-9. PMID 17931714 DOI: 10.1016/J.Bbr.2007.08.037  0.814
2007 Oomen CA, Mayer JL, de Kloet ER, Joëls M, Lucassen PJ. Brief treatment with the glucocorticoid receptor antagonist mifepristone normalizes the reduction in neurogenesis after chronic stress. The European Journal of Neuroscience. 26: 3395-401. PMID 18052970 DOI: 10.1111/J.1460-9568.2007.05972.X  0.327
2007 Schmidt MV, Oitzl M, Steenbergen P, Lachize S, Wurst W, Müller MB, de Kloet ER, Meijer OC. Ontogeny of steroid receptor coactivators in the hippocampus and their role in regulating postnatal HPA axis function. Brain Research. 1174: 1-6. PMID 17854779 DOI: 10.1016/J.Brainres.2007.08.023  0.833
2007 Brinks V, van der Mark MH, de Kloet ER, Oitzl MS. Differential MR/GR activation in mice results in emotional states beneficial or impairing for cognition. Neural Plasticity. 2007: 90163. PMID 17710249 DOI: 10.1155/2007/90163  0.71
2007 Conway-Campbell BL, McKenna MA, Wiles CC, Atkinson HC, de Kloet ER, Lightman SL. Proteasome-dependent down-regulation of activated nuclear hippocampal glucocorticoid receptors determines dynamic responses to corticosterone. Endocrinology. 148: 5470-7. PMID 17690167 DOI: 10.1210/en.2007-0585  0.583
2007 Veenema AH, de Kloet ER, de Wilde MC, Roelofs AJ, Kawata M, Buwalda B, Neumann ID, Koolhaas JM, Lucassen PJ. Differential effects of stress on adult hippocampal cell proliferation in low and high aggressive mice. Journal of Neuroendocrinology. 19: 489-98. PMID 17561881 DOI: 10.1111/J.1365-2826.2007.01555.X  0.777
2007 de Kloet ER, Derijk RH, Meijer OC. Therapy Insight: is there an imbalanced response of mineralocorticoid and glucocorticoid receptors in depression? Nature Clinical Practice. Endocrinology & Metabolism. 3: 168-79. PMID 17237843 DOI: 10.1038/ncpendmet0403  0.606
2007 de Jong IE, Oitzl MS, de Kloet ER. Adrenalectomy prevents behavioural sensitisation of mice to cocaine in a genotype-dependent manner. Behavioural Brain Research. 177: 329-39. PMID 17150264 DOI: 10.1016/J.Bbr.2006.11.015  0.673
2007 Berry A, Capone F, Giorgio M, Pelicci PG, de Kloet ER, Alleva E, Minghetti L, Cirulli F. Deletion of the life span determinant p66Shc prevents age-dependent increases in emotionality and pain sensitivity in mice. Experimental Gerontology. 42: 37-45. PMID 16809014 DOI: 10.1016/J.Exger.2006.05.018  0.529
2007 de Kloet ER, Oitzl MS, Vermetten E. Preface Progress in Brain Research. 167: ix-xi. DOI: 10.1016/S0079-6123(07)67031-9  0.617
2006 Lucassen PJ, Heine VM, Muller MB, van der Beek EM, Wiegant VM, De Kloet ER, Joels M, Fuchs E, Swaab DF, Czeh B. Stress, depression and hippocampal apoptosis. Cns & Neurological Disorders Drug Targets. 5: 531-46. PMID 17073656 DOI: 10.2174/187152706778559273  0.782
2006 Schmidt MV, Deussing JM, Oitzl MS, Ohl F, Levine S, Wurst W, Holsboer F, Müller MB, de Kloet ER. Differential disinhibition of the neonatal hypothalamic- pituitary-adrenal axis in brain-specific CRH receptor 1-knockout mice. The European Journal of Neuroscience. 24: 2291-8. PMID 17042789 DOI: 10.1111/J.1460-9568.2006.05121.X  0.825
2006 Schmidt MV, Levine S, Alam S, Harbich D, Sterlemann V, Ganea K, de Kloet ER, Holsboer F, Müller MB. Metabolic signals modulate hypothalamic-pituitary-adrenal axis activation during maternal separation of the neonatal mouse. Journal of Neuroendocrinology. 18: 865-74. PMID 17026536 DOI: 10.1111/J.1365-2826.2006.01482.X  0.614
2006 Morsink MC, Joëls M, Sarabdjitsingh RA, Meijer OC, De Kloet ER, Datson NA. The dynamic pattern of glucocorticoid receptor-mediated transcriptional responses in neuronal PC12 cells. Journal of Neurochemistry. 99: 1282-98. PMID 17026526 DOI: 10.1111/J.1471-4159.2006.04187.X  0.797
2006 DeRijk RH, Wüst S, Meijer OC, Zennaro MC, Federenko IS, Hellhammer DH, Giacchetti G, Vreugdenhil E, Zitman FG, de Kloet ER. A common polymorphism in the mineralocorticoid receptor modulates stress responsiveness. The Journal of Clinical Endocrinology and Metabolism. 91: 5083-9. PMID 17018659 DOI: 10.1210/Jc.2006-0915  0.567
2006 Saravia FE, Beauquis J, Revsin Y, Homo-Delarche F, de Kloet ER, De Nicola AF. Hippocampal neuropathology of diabetes mellitus is relieved by estrogen treatment. Cellular and Molecular Neurobiology. 26: 943-57. PMID 16807785 DOI: 10.1007/s10571-006-9096-y  0.789
2006 Herbert J, Goodyer IM, Grossman AB, Hastings MH, de Kloet ER, Lightman SL, Lupien SJ, Roozendaal B, Seckl JR. Do corticosteroids damage the brain? Journal of Neuroendocrinology. 18: 393-411. PMID 16684130 DOI: 10.1111/J.1365-2826.2006.01429.X  0.475
2006 Feldker DE, Morsink MC, Veenema AH, Datson NA, Proutski V, Lathouwers D, de Kloet ER, Vreugdenhil E. The effect of chronic exposure to highly aggressive mice on hippocampal gene expression of non-aggressive subordinates. Brain Research. 1089: 10-20. PMID 16678802 DOI: 10.1016/J.Brainres.2006.02.110  0.679
2006 Meijer OC, van der Laan S, Lachize S, Steenbergen PJ, de Kloet ER. Steroid receptor coregulator diversity: what can it mean for the stressed brain? Neuroscience. 138: 891-9. PMID 16310313 DOI: 10.1016/J.Neuroscience.2005.07.004  0.577
2006 Schmidt MV, Enthoven L, van der Mark M, Levine S, de Kloet ER, Oitzl MS. Corrigendum to "The postnatal development of the hypothalamic-pituitary-adrenal axis in the mouse" [Int. J. Dev. Neurosci. 23 (2003) 125-132] (DOI:10.1016/S0736-5748(03)00030-3) International Journal of Developmental Neuroscience. 24: 293. DOI: 10.1016/J.Ijdevneu.2006.03.003  0.79
2006 De Kloet ER, Oitzl MS. Cortisol and PTSD: Animal experiments and clinical perspectives Ptsd: Brain Mechanisms and Clinical Implications. 13-27. DOI: 10.1007/4-431-29567-4_2  0.652
2005 Dalm S, Enthoven L, Meijer OC, van der Mark MH, Karssen AM, de Kloet ER, Oitzl MS. Age-related changes in hypothalamic-pituitary-adrenal axis activity of male C57BL/6J mice. Neuroendocrinology. 81: 372-80. PMID 16276115 DOI: 10.1159/000089555  0.806
2005 van der Laan S, Lachize SB, Schouten TG, Vreugdenhil E, de Kloet ER, Meijer OC. Neuroanatomical distribution and colocalisation of nuclear receptor corepressor (N-CoR) and silencing mediator of retinoid and thyroid receptors (SMRT) in rat brain. Brain Research. 1059: 113-21. PMID 16212947 DOI: 10.1016/J.Brainres.2005.08.011  0.557
2005 Karssen AM, Meijer OC, Berry A, Sanjuan Piñol R, de Kloet ER. Low doses of dexamethasone can produce a hypocorticosteroid state in the brain. Endocrinology. 146: 5587-95. PMID 16150912 DOI: 10.1210/En.2005-0501  0.687
2005 de Kloet ER, Joëls M, Holsboer F. Stress and the brain: from adaptation to disease. Nature Reviews. Neuroscience. 6: 463-75. PMID 15891777 DOI: 10.1038/Nrn1683  0.461
2005 de Kloet ER, Sibug RM, Helmerhorst FM, Schmidt MV, Schmidt M. Stress, genes and the mechanism of programming the brain for later life. Neuroscience and Biobehavioral Reviews. 29: 271-81. PMID 15811498 DOI: 10.1016/J.Neubiorev.2004.10.008  0.552
2005 Veenema AH, Sijtsma B, Koolhaas JM, de Kloet ER. The stress response to sensory contact in mice: genotype effect of the stimulus animal. Psychoneuroendocrinology. 30: 550-7. PMID 15808924 DOI: 10.1016/J.Psyneuen.2005.01.003  0.752
2005 Revsin Y, Saravia F, Roig P, Lima A, de Kloet ER, Homo-Delarche F, De Nicola AF. Neuronal and astroglial alterations in the hippocampus of a mouse model for type 1 diabetes. Brain Research. 1038: 22-31. PMID 15748869 DOI: 10.1016/j.brainres.2004.12.032  0.788
2005 Schmidt MV, Schmidt M, Levine S, Oitzl MS, van der Mark M, Müller MB, Holsboer F, de Kloet ER. Glucocorticoid receptor blockade disinhibits pituitary-adrenal activity during the stress hyporesponsive period of the mouse. Endocrinology. 146: 1458-64. PMID 15591147 DOI: 10.1210/En.2004-1042  0.817
2005 Meijer OC, Kalkhoven E, van der Laan S, Steenbergen PJ, Houtman SH, Dijkmans TF, Pearce D, de Kloet ER. Steroid receptor coactivator-1 splice variants differentially affect corticosteroid receptor signaling. Endocrinology. 146: 1438-48. PMID 15564339 DOI: 10.1210/En.2004-0411  0.634
2005 Karssen AM, Meijer OC, de Kloet ER. Chapter 3.4 Corticosteroids and the blood-brain barrier Techniques in the Behavioral and Neural Sciences. 15: 329-340. DOI: 10.1016/S0921-0709(05)80019-7  0.52
2004 Karssen AM, Meijer O, Pons D, De Kloet ER. Localization of mRNA expression of P-glycoprotein at the blood-brain barrier and in the hippocampus. Annals of the New York Academy of Sciences. 1032: 308-11. PMID 15677438 DOI: 10.1196/Annals.1314.048  0.508
2004 De Kloet ER, Derijk R. Signaling pathways in brain involved in predisposition and pathogenesis of stress-related disease: genetic and kinetic factors affecting the MR/GR balance. Annals of the New York Academy of Sciences. 1032: 14-34. PMID 15677393 DOI: 10.1196/annals.1314.003  0.34
2004 Datson NA, Meijer L, Steenbergen PJ, Morsink MC, van der Laan S, Meijer OC, de Kloet ER. Expression profiling in laser-microdissected hippocampal subregions in rat brain reveals large subregion-specific differences in expression. The European Journal of Neuroscience. 20: 2541-54. PMID 15548198 DOI: 10.1111/J.1460-9568.2004.03738.X  0.494
2004 Veenema AH, Koolhaas JM, de Kloet ER. Basal and stress-induced differences in HPA axis, 5-HT responsiveness, and hippocampal cell proliferation in two mouse lines. Annals of the New York Academy of Sciences. 1018: 255-65. PMID 15240376 DOI: 10.1196/Annals.1296.030  0.755
2004 De Kloet ER. Hormones and the stressed brain. Annals of the New York Academy of Sciences. 1018: 1-15. PMID 15240347 DOI: 10.1196/annals.1296.001  0.344
2004 Enthoven L, Dalm S, de Kloet ER, Oitzl MS. Swim posture of mice does not affect performance in the water maze. Brain Research. 1003: 36-41. PMID 15019561 DOI: 10.1016/J.Brainres.2003.10.074  0.779
2004 Schmidt M, Enthoven L, van Woezik JH, Levine S, de Kloet ER, Oitzl MS. The dynamics of the hypothalamic-pituitary-adrenal axis during maternal deprivation. Journal of Neuroendocrinology. 16: 52-7. PMID 14962076 DOI: 10.1111/J.1365-2826.2004.01123.X  0.821
2004 Grootendorst J, Enthoven L, Dalm S, de Kloet ER, Oitzl MS. Increased corticosterone secretion and early-onset of cognitive decline in female apolipoprotein E-knockout mice. Behavioural Brain Research. 148: 167-77. PMID 14684257 DOI: 10.1016/S0166-4328(03)00188-8  0.797
2003 Feldker DE, Datson NA, Veenema AH, Proutski V, Lathouwers D, De Kloet ER, Vreugdenhil E. GeneChip analysis of hippocampal gene expression profiles of short- and long-attack-latency mice: technical and biological implications. Journal of Neuroscience Research. 74: 701-16. PMID 14635221 DOI: 10.1002/Jnr.10800  0.633
2003 de Kloet ER. Hormones, brain and stress. Endocrine Regulations. 37: 51-68. PMID 12932191  0.331
2003 Meijer OC, Karssen AM, de Kloet ER. Cell- and tIssue-specific effects of corticosteroids in relation to glucocorticoid resistance: examples from the brain. The Journal of Endocrinology. 178: 13-8. PMID 12844331 DOI: 10.1677/Joe.0.1780013  0.52
2003 de Kloet ER, Oitzl MS. Who cares for a stressed brain? The mother, the kid or both? Neurobiology of Aging. 24: S61-5; discussion S6. PMID 12829110 DOI: 10.1016/S0197-4580(03)00057-5  0.681
2003 Schmidt MV, Schmidt M, Oitzl MS, Müller MB, Ohl F, Wurst W, Holsboer F, Levine S, De Kloet ER. Regulation of the developing hypothalamic-pituitary-adrenal axis in corticotropin releasing hormone receptor 1-deficient mice. Neuroscience. 119: 589-95. PMID 12770571 DOI: 10.1016/S0306-4522(03)00097-6  0.821
2003 Schmidt MV, Schmidt M, Enthoven L, van der Mark M, Levine S, de Kloet ER, Oitzl MS. The postnatal development of the hypothalamic-pituitary-adrenal axis in the mouse. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 21: 125-32. PMID 12711350 DOI: 10.1016/S0736-5748(03)00030-3  0.838
2003 Veenema AH, Meijer OC, de Kloet ER, Koolhaas JM, Bohus BG. Differences in basal and stress-induced HPA regulation of wild house mice selected for high and low aggression. Hormones and Behavior. 43: 197-204. PMID 12614650 DOI: 10.1016/S0018-506X(02)00013-2  0.835
2003 Veenema AH, Meijer OC, de Kloet ER, Koolhaas JM. Genetic selection for coping style predicts stressor susceptibility. Journal of Neuroendocrinology. 15: 256-67. PMID 12588514 DOI: 10.1046/J.1365-2826.2003.00986.X  0.812
2003 Feldker DE, Datson NA, Veenema AH, Meulmeester E, de Kloet ER, Vreugdenhil E. Serial analysis of gene expression predicts structural differences in hippocampus of long attack latency and short attack latency mice. The European Journal of Neuroscience. 17: 379-87. PMID 12542675 DOI: 10.1046/J.1460-9568.2003.02440.X  0.64
2002 de Kloet ER, Grootendorst J, Karssen AM, Oitzl MS. Gene x environment interaction and cognitive performance: animal studies on the role of corticosterone. Neurobiology of Learning and Memory. 78: 570-7. PMID 12559836 DOI: 10.1006/Nlme.2002.4079  0.711
2002 Van Kampen M, De Kloet ER, Flügge G, Fuchs E. Blockade of glucocorticoid receptors with ORG 34116 does not normalize stress-induced symptoms in male tree shrews. European Journal of Pharmacology. 457: 207-16. PMID 12464368 DOI: 10.1016/S0014-2999(02)02664-X  0.328
2002 Schmidt MV, Schmidt M, Oitzl MS, Levine S, de Kloet ER. The HPA system during the postnatal development of CD1 mice and the effects of maternal deprivation. Brain Research. Developmental Brain Research. 139: 39-49. PMID 12414092 DOI: 10.1016/S0165-3806(02)00519-9  0.838
2002 Grootendorst J, Kempes MM, Lucassen PJ, Dalm S, de Kloet ER, Oitzl MS. Differential effect of corticosterone on spatial learning abilities in apolipoprotein E knockout and C57BL/6J mice. Brain Research. 953: 281-5. PMID 12384263 DOI: 10.1016/S0006-8993(02)03399-1  0.693
2002 Karssen AM, Meijer OC, van der Sandt IC, De Boer AG, De Lange EC, De Kloet ER. The role of the efflux transporter P-glycoprotein in brain penetration of prednisolone. The Journal of Endocrinology. 175: 251-60. PMID 12379510 DOI: 10.1677/Joe.0.1750251  0.502
2002 van Acker SA, Oitzl MS, Fluttert MF, de Kloet ER. Centrally regulated blood pressure response to vasoactive peptides is modulated by corticosterone. Journal of Neuroendocrinology. 14: 56-63. PMID 11903813 DOI: 10.1046/J.1365-2826.2002.00740.X  0.704
2001 Grootendorst J, de Kloet ER, Dalm S, Oitzl MS. Reversal of cognitive deficit of apolipoprotein E knockout mice after repeated exposure to a common environmental experience. Neuroscience. 108: 237-47. PMID 11734357 DOI: 10.1016/S0306-4522(01)00412-2  0.747
2001 Grootendorst J, Oitzl MS, Dalm S, Enthoven L, Schachner M, de Kloet ER, Sandi C. Stress alleviates reduced expression of cell adhesion molecules (NCAM, L1), and deficits in learning and corticosterone regulation of apolipoprotein E knockout mice. The European Journal of Neuroscience. 14: 1505-14. PMID 11722612 DOI: 10.1046/J.0953-816X.2001.01766.X  0.82
2001 Grootendorst J, de Kloet ER, Vossen C, Dalm S, Oitzl MS. Repeated exposure to rats has persistent genotype-dependent effects on learning and locomotor activity of apolipoprotein E knockout and C57Bl/6 mice. Behavioural Brain Research. 125: 249-59. PMID 11682116 DOI: 10.1016/S0166-4328(01)00294-7  0.719
2001 Oitzl MS, Reichardt HM, Joëls M, de Kloet ER. Point mutation in the mouse glucocorticoid receptor preventing DNA binding impairs spatial memory. Proceedings of the National Academy of Sciences of the United States of America. 98: 12790-5. PMID 11606764 DOI: 10.1073/Pnas.231313998  0.714
2001 Schaaf MJ, Workel JO, Lesscher HM, Vreugdenhil E, Oitzl MS, de Kloet ER. Correlation between hippocampal BDNF mRNA expression and memory performance in senescent rats. Brain Research. 915: 227-33. PMID 11595212 DOI: 10.1016/S0006-8993(01)02855-4  0.698
2001 Sibug RM, Oitzl MS, Workel JO, de Kloet ER. Maternal deprivation increases 5-HT(1A) receptor expression in the CA1 and CA3 areas of senescent Brown Norway rats. Brain Research. 912: 95-8. PMID 11520497 DOI: 10.1016/S0006-8993(01)02654-3  0.694
2001 Workel JO, Oitzl MS, Fluttert M, Lesscher H, Karssen A, de Kloet ER. Differential and age-dependent effects of maternal deprivation on the hypothalamic-pituitary-adrenal axis of brown norway rats from youth to senescence. Journal of Neuroendocrinology. 13: 569-80. PMID 11442771 DOI: 10.1046/J.1365-2826.2001.00668.X  0.75
2001 Karssen AM, Meijer OC, van der Sandt IC, Lucassen PJ, de Lange EC, de Boer AG, de Kloet ER. Multidrug resistance P-glycoprotein hampers the access of cortisol but not of corticosterone to mouse and human brain. Endocrinology. 142: 2686-94. PMID 11356720 DOI: 10.1210/Endo.142.6.8213  0.524
2001 Lucassen PJ, Müller MB, Holsboer F, Bauer J, Holtrop A, Wouda J, Hoogendijk WJ, De Kloet ER, Swaab DF. Hippocampal apoptosis in major depression is a minor event and absent from subareas at risk for glucocorticoid overexposure. The American Journal of Pathology. 158: 453-68. PMID 11159183 DOI: 10.1016/S0002-9440(10)63988-0  0.332
2001 de Kloet ER. Stress in the brain. European Journal of Pharmacology. 405: 187-98. PMID 11033326 DOI: 10.1016/s0014-2999(00)00552-5  0.325
2001 Sibug RM, Compaan JC, Meijer OC, Van der Gugten J, Olivier B, De Kloet ER. Effects of flesinoxan on corticosteroid receptor expression in the rat hippocampus. European Journal of Pharmacology. 404: 111-9. PMID 10980269 DOI: 10.1016/S0014-2999(00)00605-1  0.566
2000 de Kloet ER, Meijer OC, Vreugdenhil E, Joëls M. The Yin and Yang of nuclear receptors: symposium on nuclear receptors in brain, Oegstgeest, The Netherlands, 13-14 April 2000. Trends in Endocrinology and Metabolism: Tem. 11: 245-8. PMID 11273562 DOI: 10.1016/S1043-2760(00)00284-8  0.522
2000 Oitzl MS, Workel JO, Fluttert M, Frösch F, De Kloet ER. Maternal deprivation affects behaviour from youth to senescence: amplification of individual differences in spatial learning and memory in senescent Brown Norway rats. The European Journal of Neuroscience. 12: 3771-80. PMID 11029647 DOI: 10.1046/J.1460-9568.2000.00231.X  0.707
2000 Cabrera R, Korte SM, Lentjes EG, Romijn F, Schönbaum E, De Nicola A, De Kloet ER. The amount of free corticosterone is increased during lipopolysaccharide-induced fever. Life Sciences. 66: 553-62. PMID 10794511 DOI: 10.1016/S0024-3205(99)00628-1  0.681
2000 de Kloet ER, Van Acker SA, Sibug RM, Oitzl MS, Meijer OC, Rahmouni K, de Jong W. Brain mineralocorticoid receptors and centrally regulated functions. Kidney International. 57: 1329-36. PMID 10760063 DOI: 10.1046/J.1523-1755.2000.00971.X  0.792
1999 Saravia FE, Grillo CA, Ferrini M, Roig P, Lima AE, de Kloet ER, De Nicola AF. Changes of hypothalamic and plasma vasopressin in rats with deoxycorticosterone-acetate induced salt appetite. The Journal of Steroid Biochemistry and Molecular Biology. 70: 47-57. PMID 10529002 DOI: 10.1016/S0960-0760(99)00094-1  0.629
1999 de Kloet ER, Oitzl MS, Joëls M. Stress and cognition: are corticosteroids good or bad guys? Trends in Neurosciences. 22: 422-6. PMID 10481183 DOI: 10.1016/S0166-2236(99)01438-1  0.714
1999 van Oers HJ, de Kloet ER, Levine S. Persistent effects of maternal deprivation on HPA regulation can be reversed by feeding and stroking, but not by dexamethasone. Journal of Neuroendocrinology. 11: 581-8. PMID 10447795  0.819
1998 Gómez F, De Kloet ER, Armario A. Glucocorticoid negative feedback on the HPA axis in five inbred rat strains. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 274: R420-R427. PMID 29587006 DOI: 10.1152/ajpregu.1998.274.2.R420  0.302
1998 Oitzl MS, Fluttert M, Sutanto W, de Kloet ER. Continuous blockade of brain glucocorticoid receptors facilitates spatial learning and memory in rats. The European Journal of Neuroscience. 10: 3759-66. PMID 9875354 DOI: 10.1046/J.1460-9568.1998.00381.X  0.72
1998 van Oers HJ, de Kloet ER, Levine S. Early vs. late maternal deprivation differentially alters the endocrine and hypothalamic responses to stress. Brain Research. Developmental Brain Research. 111: 245-52. PMID 9838147  0.829
1998 van Oers HJ, de Kloet ER, Whelan T, Levine S. Maternal deprivation effect on the infant's neural stress markers is reversed by tactile stimulation and feeding but not by suppressing corticosterone. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 10171-9. PMID 9822770  0.827
1998 Sibug RM, Compaan JC, Meijer OC, Van der Gugten J, Olivier B, De Kloet ER. Flesinoxan treatment reduces 5-HT1A receptor mRNA in the dentate gyrus independently of high plasma corticosterone levels. European Journal of Pharmacology. 353: 207-14. PMID 9726650 DOI: 10.1016/S0014-2999(98)00417-8  0.569
1998 Grillo CA, Saravia F, Ferrini M, Piroli G, Roig P, García SI, de Kloet ER, De Nicola AF. Increased expression of magnocellular vasopressin mRNA in rats with deoxycorticosterone-acetate induced salt appetite. Neuroendocrinology. 68: 105-15. PMID 9705577 DOI: 10.1159/000054356  0.632
1998 De Nicola AF, Ferrini M, Gonzalez SL, Gonzalez Deniselle MC, Grillo CA, Piroli G, Saravia F, de Kloet ER. Regulation of gene expression by corticoid hormones in the brain and spinal cord. The Journal of Steroid Biochemistry and Molecular Biology. 65: 253-72. PMID 9699880 DOI: 10.1016/S0960-0760(97)00190-8  0.626
1998 Meijer OC, Kortekaas R, Oitzl MS, de Kloet ER. Acute rise in corticosterone facilitates 5-HT(1A) receptor-mediated behavioural responses. European Journal of Pharmacology. 351: 7-14. PMID 9698199 DOI: 10.1016/S0014-2999(98)00289-1  0.775
1998 De Kloet ER, Vreugdenhil E, Oitzl MS, Joëls M. Brain corticosteroid receptor balance in health and disease. Endocrine Reviews. 19: 269-301. PMID 9626555 DOI: 10.1210/Edrv.19.3.0331  0.744
1998 van Oers HJ, de Kloet ER, Li C, Levine S. The ontogeny of glucocorticoid negative feedback: influence of maternal deprivation. Endocrinology. 139: 2838-46. PMID 9607792 DOI: 10.1210/Endo.139.6.6037  0.807
1997 De Kloet ER, Vreugdenhil E, Oitzl MS, Joëls M. Glucocorticoid feedback resistance. Trends in Endocrinology and Metabolism: Tem. 8: 26-33. PMID 18406783 DOI: 10.1016/S1043-2760(96)00205-6  0.788
1997 Oitzl MS, de Kloet ER, Joëls M, Schmid W, Cole TJ. Spatial learning deficits in mice with a targeted glucocorticoid receptor gene disruption. The European Journal of Neuroscience. 9: 2284-96. PMID 9464923 DOI: 10.1111/J.1460-9568.1997.Tb01646.X  0.722
1997 Ferrini MG, Grillo CA, Piroli G, de Kloet ER, De Nicola AF. Sex difference in glucocorticoid regulation of vasopressin mRNA in the paraventricular hypothalamic nucleus. Cellular and Molecular Neurobiology. 17: 671-86. PMID 9442352 DOI: 10.1023/A:1022538120627  0.654
1997 van Haarst AD, Oitzl MS, de Kloet ER. Facilitation of feedback inhibition through blockade of glucocorticoid receptors in the hippocampus. Neurochemical Research. 22: 1323-8. PMID 9355104 DOI: 10.1023/A:1022010904600  0.736
1997 Meijer OC, Cole TJ, Schmid W, Schütz G, Joëls M, De Kloet ER. Regulation of hippocampal 5-HT1A receptor mRNA and binding in transgenic mice with a targeted disruption of the glucocorticoid receptor. Brain Research. Molecular Brain Research. 46: 290-6. PMID 9191104 DOI: 10.1016/S0169-328X(97)00002-8  0.549
1997 Nicot A, Rowe WB, De Kloet ER, Betancur C, Jessop DS, Lightman SL, Quirion R, Rostène W, Bérod A. Endogenous neurotensin regulates hypothalamic-pituitary-adrenal axis activity and peptidergic neurons in the rat hypothalamic paraventricular nucleus. Journal of Neuroendocrinology. 9: 263-9. PMID 9147289 DOI: 10.1046/J.1365-2826.1997.00581.X  0.567
1996 Korte-Bouws GA, Korte SM, De Kloet ER, Bohus B. Blockade of corticosterone synthesis reduces serotonin turnover in the dorsal hippocampus of the rat as measured by microdialysis. Journal of Neuroendocrinology. 8: 877-81. PMID 8933365 DOI: 10.1046/J.1365-2826.1996.05389.X  0.647
1996 Korte SM, Meijer OC, de Kloet ER, Buwalda B, Keijser J, Sluyter F, van Oortmerssen G, Bohus B. Enhanced 5-HT1A receptor expression in forebrain regions of aggressive house mice. Brain Research. 736: 338-43. PMID 8930340 DOI: 10.1016/0006-8993(96)00723-8  0.754
1996 Korte SM, Buwalda B, De Kloet ER, Bohus B. Adrenaline release by the 5-HT1A receptor agonist 8-OH-DPAT is partly responsible for pituitary activation. European Journal of Pharmacology. 309: 281-6. PMID 8874152 DOI: 10.1016/0014-2999(96)00356-1  0.674
1996 De Kloet ER, Korte SM, Rots NY, Kruk MR. Stress hormones, genotype, and brain organization. Implications for aggression. Annals of the New York Academy of Sciences. 794: 179-91. PMID 8853602 DOI: 10.1111/j.1749-6632.1996.tb32520.x  0.551
1996 Rots NY, de Jong J, Workel JO, Levine S, Cools AR, De Kloet ER. Neonatal maternally deprived rats have as adults elevated basal pituitary-adrenal activity and enhanced susceptibility to apomorphine. Journal of Neuroendocrinology. 8: 501-6. PMID 8843018  0.349
1996 Korte SM, De Kloet ER, Buwalda B, Bouman SD, Bohus B. Antisense to the glucocorticoid receptor in hippocampal dentate gyrus reduces immobility in forced swim test. European Journal of Pharmacology. 301: 19-25. PMID 8773442 DOI: 10.1016/0014-2999(96)00064-7  0.672
1996 Rots NY, Workel J, Oitzl MS, Bérod A, Rostène W, Cools AR, De Kloet ER. Development of divergence in dopamine responsiveness in genetically selected rat lines is preceded by changes in pituitary-adrenal activity. Brain Research. Developmental Brain Research. 92: 164-71. PMID 8738123 DOI: 10.1016/0165-3806(95)00214-6  0.711
1996 Sutanto W, Rosenfeld P, de Kloet ER, Levine S. Long-term effects of neonatal maternal deprivation and ACTH on hippocampal mineralocorticoid and glucocorticoid receptors. Brain Research. Developmental Brain Research. 92: 156-63. PMID 8738122  0.331
1996 Korte SM, Korte-Bouws GA, Koob GF, De Kloet ER, Bohus B. Mineralocorticoid and glucocorticoid receptor antagonists in animal models of anxiety. Pharmacology, Biochemistry, and Behavior. 54: 261-7. PMID 8728567 DOI: 10.1016/0091-3057(95)02172-8  0.72
1996 Hesen W, Karst H, Meijer O, Cole TJ, Schmid W, de Kloet ER, Schütz G, Joëls M. Hippocampal Cell Responses in Mice with a Targeted Glucocorticoid Receptor Gene Disruption The Journal of Neuroscience. 16: 6766-6774. DOI: 10.1523/Jneurosci.16-21-06766.1996  0.594
1995 Korte SM, de Boer SF, de Kloet ER, Bohus B. Anxiolytic-like effects of selective mineralocorticoid and glucocorticoid antagonists on fear-enhanced behavior in the elevated plus-maze. Psychoneuroendocrinology. 20: 385-94. PMID 8532822 DOI: 10.1016/0306-4530(94)00069-7  0.687
1995 Vallee SM, Grillo CA, Gonzalez S, Cosen-Binker L, de Kloet ER, McEwen BS, De Nicola AF. Further studies in deoxycorticosterone acetate treated rats: brain content of mineralocorticoid and glucocorticoid receptors and effect of steroid antagonists on salt intake. Neuroendocrinology. 61: 117-24. PMID 7753331 DOI: 10.1159/000126832  0.714
1995 Korte SM, Buwalda B, Meijer O, De Kloet ER, Bohus B. Socially defeated male rats display a blunted adrenocortical response to a low dose of 8-OH-DPAT. European Journal of Pharmacology. 272: 45-50. PMID 7713148 DOI: 10.1016/0014-2999(94)00621-D  0.741
1994 Schöbitz B, Holsboer F, Sutanto W, Gross G, Schönbaum E, de Kloet ER. Corticosterone modulates interleukin-evoked fever in the rat. Neuroendocrinology. 59: 387-95. PMID 8202220 DOI: 10.1159/000126682  0.332
1994 Wiegers GJ, Reul JM, Holsboer F, de Kloet ER. Enhancement of rat splenic lymphocyte mitogenesis after short term preexposure to corticosteroids in vitro. Endocrinology. 135: 2351-7. PMID 7988417 DOI: 10.1210/Endo.135.6.7988417  0.642
1994 Schöbitz B, Sutanto W, Carey MP, Holsboer F, de Kloet ER. Endotoxin and interleukin 1 decrease the affinity of hippocampal mineralocorticoid (type I) receptor in parallel to activation of the hypothalamic-pituitary-adrenal axis. Neuroendocrinology. 60: 124-33. PMID 7969769 DOI: 10.1159/000126742  0.445
1994 Schöbitz B, De Kloet ER, Holsboer F. Gene expression and function of interleukin 1, interleukin 6 and tumor necrosis factor in the brain. Progress in Neurobiology. 44: 397-432. PMID 7886232 DOI: 10.1016/0301-0082(94)90034-5  0.317
1994 Cirulli F, van Oers H, De Kloet ER, Levine S. Differential influence of corticosterone and dexamethasone on schedule-induced polydipsia in adrenalectomized rats. Behavioural Brain Research. 65: 33-9. PMID 7880452 DOI: 10.1016/0166-4328(94)90070-1  0.629
1994 Korte SM, Buwalda B, de Kloet ER, Bohus B. Social defeat impairs plasma corticosterone response to the 5-HT1A agonist 8-OH-DPAT in the rat. Annals of the New York Academy of Sciences. 746: 426-8. PMID 7825906 DOI: 10.1111/J.1749-6632.1994.Tb39275.X  0.638
1993 Schöbitz B, Van Den Dobbelsteen M, Holsboer F, Sutanto W, De Kloet ER. Regulation of interleukin 6 gene expression in rat. Endocrinology. 132: 1569-76. PMID 8462455 DOI: 10.1210/endo.132.4.8462455  0.327
1993 Rothuizen J, Reul JM, van Sluijs FJ, Mol JA, Rijnberk A, de Kloet ER. Increased neuroendocrine reactivity and decreased brain mineralocorticoid receptor-binding capacity in aged dogs. Endocrinology. 132: 161-8. PMID 8380372 DOI: 10.1210/endo.132.1.8380372  0.608
1993 Schöbitz B, de Kloet ER, Sutanto W, Holsboer F. Cellular localization of interleukin 6 mRNA and interleukin 6 receptor mRNA in rat brain. The European Journal of Neuroscience. 5: 1426-35. PMID 8287192 DOI: 10.1111/J.1460-9568.1993.Tb00210.X  0.343
1993 Wiegers GJ, Croiset G, Reul JM, Holsboer F, de Kloet ER. Differential effects of corticosteroids on rat peripheral blood T-lymphocyte mitogenesis in vivo and in vitro. The American Journal of Physiology. 265: E825-30. PMID 8279536 DOI: 10.1152/Ajpendo.1993.265.6.E825  0.616
1993 Rosenfeld P, van Eekelen JA, Levine S, de Kloet ER. Ontogeny of corticosteroid receptors in the brain. Cellular and Molecular Neurobiology. 13: 295-319. PMID 8252605 DOI: 10.1007/Bf00711575  0.66
1992 Elands J, de Kloet ER, de Wied D. Neurohypophyseal hormone receptors: relation to behavior. Progress in Brain Research. 91: 459-64. PMID 1329149  0.582
1992 Schöbitz B, Holsboer F, Kikkert R, Sutanto W, De Kloet ER. Peripheral and central regulation of IL-6 gene expression in endotoxin-treated rats. Endocrine Regulations. 26: 103-9. PMID 1308153  0.37
1991 Voorhuis TA, De Kloet ER, De Wied D. Ontogenetic and seasonal changes in immunoreactive vasotocin in the canary brain. Brain Research. Developmental Brain Research. 61: 23-31. PMID 1914156 DOI: 10.1016/0165-3806(91)90110-5  0.575
1991 Voorhuis TA, De Kloet ER, De Wied D. Effect of a vasotocin analog on singing behavior in the canary. Hormones and Behavior. 25: 549-59. PMID 1813380 DOI: 10.1016/0018-506X(91)90020-I  0.58
1991 Rothuizen J, Reul JM, Rijnberk A, Mol JA, de Kloet ER. Aging and the hypothalamus-pituitary-adrenocortical axis, with special reference to the dog. Acta Endocrinologica. 125: 73-6. PMID 1801505  0.629
1991 Reul JM, Rothuizen J, de Kloet ER. Age-related changes in the dog hypothalamic-pituitary-adrenocortical system: neuroendocrine activity and corticosteroid receptors. The Journal of Steroid Biochemistry and Molecular Biology. 40: 63-9. PMID 1659883  0.619
1990 de Kloet ER, Reul JM, Sutanto W. Corticosteroids and the brain. The Journal of Steroid Biochemistry and Molecular Biology. 37: 387-94. PMID 2257242  0.629
1990 Reul JM, Sutanto W, van Eekelen JA, Rothuizen J, de Kloet ER. Central action of adrenal steroids during stress and adaptation. Advances in Experimental Medicine and Biology. 274: 243-56. PMID 2239425  0.612
1990 Reul JM, de Kloet ER, van Sluijs FJ, Rijnberk A, Rothuizen J. Binding characteristics of mineralocorticoid and glucocorticoid receptors in dog brain and pituitary. Endocrinology. 127: 907-15. PMID 2164924 DOI: 10.1210/endo-127-2-907  0.577
1990 Rosenfeld P, Sutanto W, Levine S, de Kloet ER. Ontogeny of mineralocorticoid (type 1) receptors in brain and pituitary: an in vivo autoradiographical study. Brain Research. Developmental Brain Research. 52: 57-62. PMID 2158866 DOI: 10.1016/0165-3806(90)90221-J  0.666
1988 Rosenfeld P, Van Eekelen JA, Levine S, De Kloet ER. Ontogeny of the type 2 glucocorticoid receptor in discrete rat brain regions: an immunocytochemical study. Brain Research. 470: 119-27. PMID 3409041 DOI: 10.1016/0165-3806(88)90207-6  0.65
1988 Rosenfeld P, Sutanto W, Levine S, De Kloet ER. Ontogeny of type I and type II corticosteroid receptors in the rat hippocampus. Brain Research. 470: 113-8. PMID 3409040 DOI: 10.1016/0165-3806(88)90206-4  0.616
1988 Sutanto W, van Eekelen JA, Reul JM, de Kloet ER. Species-specific topography of corticosteroid receptor types in rat and hamster brain. Neuroendocrinology. 47: 398-404. PMID 3399027  0.548
1988 Sutanto W, Reul JM, van Eekelen JA, de Kloet ER. Corticosteroid receptor analyses in rat and hamster brains reveal species specificity in the type I and type II receptors. Journal of Steroid Biochemistry. 30: 417-20. PMID 3386270  0.561
1988 Voorhuis TA, Kiss JZ, de Kloet ER, de Wied D. Testosterone-sensitive vasotocin-immunoreactive cells and fibers in the canary brain. Brain Research. 442: 139-46. PMID 3359249 DOI: 10.1016/0006-8993(88)91441-2  0.556
1988 Kiss JZ, Van Eekelen JA, Reul JM, Westphal HM, De Kloet ER. Glucocorticoid receptor in magnocellular neurosecretory cells. Endocrinology. 122: 444-9. PMID 3338408 DOI: 10.1210/endo-122-2-444  0.58
1988 De Kloet ER, Rosenfeld P, Van Eekelen JA, Sutanto W, Levine S. Stress, glucocorticoids and development. Progress in Brain Research. 73: 101-20. PMID 3047791 DOI: 10.1016/S0079-6123(08)60500-2  0.663
1988 Voorhuis TA, de Kloet ER, de Wied D. The distribution and plasticity of [3H]vasopressin-labelled specific binding sites in the canary brain. Brain Research. 457: 148-53. PMID 2971421 DOI: 10.1016/0006-8993(88)90067-4  0.57
1988 Reul JM, Tonnaer JA, De Kloet ER. Neurotrophic ACTH analogue promotes plasticity of type I corticosteroid receptor in brain of senescent male rats. Neurobiology of Aging. 9: 253-60. PMID 2840588  0.572
1988 Lebouille JL, Burbach JP, De Kloet ER, Wiegant VM, Sweep CG, De Wied D. Leu-Phe cleaving endopeptidase activity, gamma-endorphin, and beta-endorphin in the rat pituitary gland and brain. Effect of adrenalectomy and corticosterone substitution. Neuroendocrinology. 47: 7-12. PMID 2448702  0.578
1987 Kiss JZ, Voorhuis TA, van Eekelen JA, de Kloet ER, de Wied D. Organization of vasotocin-immunoreactive cells and fibers in the canary brain. The Journal of Comparative Neurology. 263: 347-64. PMID 3667983 DOI: 10.1002/cne.902630304  0.544
1987 de Kloet ER, Reul JM, van den Bosch FR, Tonnaer JA, Saito H. Ginsenoside RG1 and corticosteroid receptors in rat brain. Endocrinologia Japonica. 34: 213-20. PMID 3622389  0.6
1987 Reul JM, van den Bosch FR, de Kloet ER. Differential response of type I and type II corticosteroid receptors to changes in plasma steroid level and circadian rhythmicity. Neuroendocrinology. 45: 407-12. PMID 3587523  0.583
1987 Reul JM, van den Bosch FR, de Kloet ER. Relative occupation of type-I and type-II corticosteroid receptors in rat brain following stress and dexamethasone treatment: functional implications. The Journal of Endocrinology. 115: 459-67. PMID 3443807  0.59
1987 De Kloet ER, Ratka A, Reul JM, Sutanto W, Van Eekelen JA. Corticosteroid receptor types in brain: regulation and putative function. Annals of the New York Academy of Sciences. 512: 351-61. PMID 3327424  0.557
1987 Azmitia EC, de Kloet ER. ACTH neuropeptide stimulation of serotonergic neuronal maturation in tissue culture: modulation by hippocampal cells. Progress in Brain Research. 72: 311-8. PMID 3039579 DOI: 10.1016/S0079-6123(08)60217-4  0.51
1987 De Kloet ER, Reul JM. Feedback action and tonic influence of corticosteroids on brain function: a concept arising from the heterogeneity of brain receptor systems. Psychoneuroendocrinology. 12: 83-105. PMID 3037584  0.613
1987 De Wied D, De Kloet ER. Pro-opiomelanocortin (POMC) as homeostatic control system. Annals of the New York Academy of Sciences. 512: 328-37. PMID 2831780  0.523
1986 de Kloet ER, Reul JM, de Ronde FS, Bloemers M, Ratka A. Function and plasticity of brain corticosteroid receptor systems: action of neuropeptides. Journal of Steroid Biochemistry. 25: 723-31. PMID 3807361 DOI: 10.1016/0022-4731(86)90301-8  0.615
1986 Reul JM, de Kloet ER. Anatomical resolution of two types of corticosterone receptor sites in rat brain with in vitro autoradiography and computerized image analysis. Journal of Steroid Biochemistry. 24: 269-72. PMID 3702410  0.579
1986 McEwen BS, De Kloet ER, Rostene W. Adrenal steroid receptors and actions in the nervous system. Physiological Reviews. 66: 1121-88. PMID 3532143 DOI: 10.1152/Physrev.1986.66.4.1121  0.497
1985 Reul JM, de Kloet ER. Two receptor systems for corticosterone in rat brain: microdistribution and differential occupation. Endocrinology. 117: 2505-11. PMID 2998738 DOI: 10.1210/endo-117-6-2505  0.612
1985 de Kloet ER, Voorhuis TA, Burbach JP, de Wied D. Autoradiographic localization of binding sites for the arginine-vasopressin (VP) metabolite, VP4-9, in rat brain. Neuroscience Letters. 56: 7-11. PMID 2989735 DOI: 10.1016/0304-3940(85)90432-X  0.582
1984 Laczi F, Gaffori O, Fekete M, de Kloet ER, de Wied D. Levels of arginine-vasopressin in cerebrospinal fluid during passive avoidance behavior in rats. Life Sciences. 34: 2385-91. PMID 6727572 DOI: 10.1016/0024-3205(84)90426-0  0.582
1984 Burbach JP, De Hoop MJ, Schmale H, Richter D, De Kloet ER, Ten Haaf JA, De Wied D. Differential responses to osmotic stress of vasopressin-neurophysin mRNA in hypothalamic nuclei. Neuroendocrinology. 39: 582-4. PMID 6514139 DOI: 10.1159/000124040  0.61
1984 van Heuven-Nolsen D, De Kloet ER, De Wied D, Versteeg DH. Microinjection of vasopressin and two related peptides into the amygdala: enhancing effect on local dopamine neurotransmission. Brain Research. 293: 191-5. PMID 6142753 DOI: 10.1016/0006-8993(84)91470-7  0.547
1983 De Kloet ER, Drago F, Mezey E, Bohus B, De Wied D. Pituitary stalk section transiently impairs the acquisition of shuttle box avoidance behavior. Physiology & Behavior. 30: 499-502. PMID 6878451 DOI: 10.1016/0031-9384(83)90211-1  0.687
1983 Laczi F, Gaffori O, de Kloet ER, de Wied D. Differential responses in immunoreactive arginine-vasopressin content of microdissected brain regions during passive avoidance behavior. Brain Research. 260: 342-6. PMID 6831206  0.61
1983 Laczi F, Gaffori O, De Kloet ER, De Wied D. Arginine-vasopressin content of hippocampus and amygdala during passive avoidance behavior in rats. Brain Research. 280: 309-15. PMID 6652491 DOI: 10.1016/0006-8993(83)90060-4  0.606
1982 Versteeg DH, Kovács GL, Bohus B, de Kloet ER, de Wied D. Effect of des-Tyr1-gamma-endorphin and des-Tyr1-alpha-endorphin on alpha-MPT-induced catecholamine disappearance in rat brain nuclei: a dose--response study. Brain Research. 231: 343-51. PMID 6120024 DOI: 10.1016/0006-8993(82)90371-7  0.701
1981 Burbach JP, De Kloet ER, Schotman P, De Wied D. Proteolytic conversion of beta-endorphin by brain synaptic membranes. Characterization of generated beta-endorphin fragments and proposed metabolic pathway. The Journal of Biological Chemistry. 256: 12463-9. PMID 6271786  0.523
1981 van Dijk AM, van Wimersma Greidanus TB, Burbach JP, de Kloet ER, de Wied D. Brain adrenocorticotrophin after adrenalectomy and sham-operation of rats. The Journal of Endocrinology. 88: 243-53. PMID 6259267  0.747
1980 Burbach JP, Loeber JG, Verhoef J, Wiegant VM, de Kloet ER, de Wied D. Selective conversion of beta-endorphin into peptides related to gamma- and alpha-endorphin. Nature. 283: 96-7. PMID 7350533 DOI: 10.1038/283096A0  0.541
1980 Burbach JP, Schotman P, Verhoef J, de Kloet ER, de Wied D. Conversion of des-tyrosine-gamma-endorphin by brain synaptic membrane associated peptidases: identification of generated peptide fragments. Biochemical and Biophysical Research Communications. 97: 995-1004. PMID 7008797  0.53
1980 Burbach JP, De Kloet ER, De Wied D. Oxytocin biotransformation in the rat limbic brain: characterization of peptidase activities and significance in the formation of oxytocin fragments. Brain Research. 202: 401-14. PMID 7002262  0.574
1979 Versteeg DH, De Kloet ER, De Wied D. Effects of alpha-endorphin, beta-endorphin and (des-tyr1)-gamma-endorphin on alpha-MPT-induced cateholamine disappearance in discrete regions of the rat brain. Brain Research. 179: 85-92. PMID 509235 DOI: 10.1016/0006-8993(79)90492-X  0.548
1979 Kovács GL, Bohus B, Versteeg DH, de Kloet ER, de Wied D. Effect of oxytocin and vasopressin on memory consolidation: sites of action and catecholaminergic correlates after local microinjection into limbic-midbrain structures. Brain Research. 175: 303-14. PMID 487159 DOI: 10.1016/0006-8993(79)91009-6  0.728
1979 Dorsa DM, de Kloet ER, Mezey E, de Wied D. Pituitary-brain transport of neurotensin: functional significance of retrograde transport. Endocrinology. 104: 1663-6. PMID 446387 DOI: 10.1210/endo-104-6-1663  0.702
1979 Versteeg DH, De Kloet ER, Greidanus TV, De Wied D. Vasopressin modulates the activity of catecholamine containing neurons in specific brain regions. Neuroscience Letters. 11: 69-73. PMID 219400 DOI: 10.1016/0304-3940(79)90058-2  0.586
1979 Burbach JP, Loeber JG, Verhoef J, de Kloet ER, van Ree JM, de Wied D. Schizophrenia and degradation of endorphins in cerebrospinal fluid. Lancet. 2: 480-1. PMID 89549  0.493
1979 Burbach JP, Loeber JG, Verhoef J, de Kloet ER, de Wied D. Biotransformation of endorphins by a synaptosomal plasma membrane preparation of rat brain and by human serum. Biochemical and Biophysical Research Communications. 86: 1296-303. PMID 35164  0.563
1978 Versteeg DH, Tanaka M, De Kloet ER, Van Ree JM, De Wied D. Prolyl-leucyl-glycinamide (PLG); regional effects on alpha-MPT-induced catecholamine disappearance in rat brain. Brain Research. 143: 561-6. PMID 647380  0.574
1978 Mezey E, Palkovits M, de Kloet ER, Verhoef J, de Wied D. Evidence for pituitary-brain transport of a behaviorally potent ACTH analog. Life Sciences. 22: 831-8. PMID 205745  0.563
1977 Tanaka M, de Kloet ER, de Wied D, Versteeg DH. Arginine8-vasopressin affects catecholamine metabolism in specific brain nuclei. Life Sciences. 20: 1799-808. PMID 875620  0.561
1976 De Kloet ER, McEwen BS. Differences between cytosol receptor complexes with corticosterone and dexamethasone in hippocampal tissue from rat brain. Biochimica Et Biophysica Acta. 421: 124-32. PMID 174735 DOI: 10.1016/0304-4165(76)90176-8  0.46
1976 De Kloet ER, McEwen BS. A putative glucocorticoid receptor and a transcortin-like macromolecule in pituitary cytosol. Biochimica Et Biophysica Acta. 421: 115-23. PMID 174733 DOI: 10.1016/0304-4165(76)90175-6  0.473
1975 McEwen BS, Luine VN, Plapinger L, de Kloet ER. Putative estrogen and glucocorticoid receptors in the limbic brain. Journal of Steroid Biochemistry. 6: 971-7. PMID 170463 DOI: 10.1016/0022-4731(75)90337-4  0.688
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