| Year |
Citation |
Score |
| 2023 |
Revu SK, Yang W, Rajasundaram D, Brady A, Majumder S, Gaffen SL, Hawse W, Xia Z, McGeachy MJ. Human IL-17A protein production is controlled through a PIP5K1α-dependent translational checkpoint. Science Signaling. 16: eabo6555. PMID 37874883 DOI: 10.1126/scisignal.abo6555 |
0.529 |
|
| 2023 |
Taylor TC, Coleman BM, Arunkumar SP, Dey I, Dillon JT, Ponde NO, Poholek AC, Schwartz DM, McGeachy MJ, Conti HR, Gaffen SL. IκBζ is an essential mediator of immunity to oropharyngeal candidiasis. Cell Host & Microbe. PMID 37725983 DOI: 10.1016/j.chom.2023.08.016 |
0.87 |
|
| 2023 |
Ponde NO, Shoger KE, Khatun MS, Sarkar MK, Dey I, Taylor TC, Cisney RN, Arunkumar SP, Gudjonsson JE, Kolls JK, Gottschalk RA, Gaffen SL. SARS-CoV-2 ORF8 Mediates Signals in Macrophages and Monocytes through MyD88 Independently of the IL-17 Receptor. Journal of Immunology (Baltimore, Md. : 1950). PMID 37265402 DOI: 10.4049/jimmunol.2300110 |
0.666 |
|
| 2023 |
Iliev ID, Lin WY, Gaffen SL. When IL-17 gets on your nerves. Cell. 186: 466-468. PMID 36736299 DOI: 10.1016/j.cell.2022.12.048 |
0.515 |
|
| 2022 |
Aggor FE, Bertolini M, Zhou C, Taylor TC, Abbott DA, Musgrove J, Bruno VM, Hand TW, Gaffen SL. A gut-oral microbiome-driven axis controls oropharyngeal candidiasis through retinoic acid. Jci Insight. 7. PMID 36134659 DOI: 10.1172/jci.insight.160348 |
0.868 |
|
| 2022 |
Ponde NO, Lortal L, Tsavou A, Hepworth OW, Wickramasinghe DN, Ho J, Richardson JP, Moyes DL, Gaffen SL, Naglik JR. Receptor-kinase EGFR-MAPK adaptor proteins mediate the epithelial response to Candida albicans via the cytolytic peptide toxin, candidalysin. The Journal of Biological Chemistry. 102419. PMID 36037968 DOI: 10.1016/j.jbc.2022.102419 |
0.611 |
|
| 2022 |
Taylor TC, Li Y, Li DD, Majumder S, McGeachy MJ, Biswas PS, Gingras S, Gaffen SL. Arid5a Mediates an IL-17-Dependent Pathway That Drives Autoimmunity but Not Antifungal Host Defense. Journal of Immunology (Baltimore, Md. : 1950). PMID 35940634 DOI: 10.4049/jimmunol.2200132 |
0.709 |
|
| 2022 |
Nikou SA, Zhou C, Griffiths JS, Kotowicz NK, Coleman BM, Green MJ, Moyes DL, Gaffen SL, Naglik JR, Parker PJ. The toxin candidalysin mediates distinct epithelial inflammatory responses through p38 and EGFR-ERK pathways. Science Signaling. 15: eabj6915. PMID 35380879 DOI: 10.1126/scisignal.abj6915 |
0.817 |
|
| 2022 |
Li DD, Jawale CV, Zhou C, Lin L, Trevejo-Nunez GJ, Rahman SA, Mullet SJ, Das J, Wendell SG, Delgoffe GM, Lionakis MS, Gaffen SL, Biswas PS. Fungal sensing enhances neutrophil metabolic fitness by regulating antifungal Glut1 activity. Cell Host & Microbe. PMID 35316647 DOI: 10.1016/j.chom.2022.02.017 |
0.729 |
|
| 2022 |
Trevejo-Nuñez G, Lin B, Fan L, Aggor FEY, Biswas PS, Chen K, Gaffen SL. Regnase-1 Deficiency Restrains Klebsiella pneumoniae Infection by Regulation of a Type I Interferon Response. Mbio. e0379221. PMID 35100872 DOI: 10.1128/mbio.03792-21 |
0.816 |
|
| 2022 |
Lin X, Gaudino SJ, Jang KK, Bahadur T, Singh A, Banerjee A, Beaupre M, Chu T, Wong HT, Kim CK, Kempen C, Axelrad J, Huang H, Khalid S, Shah V, ... ... Gaffen SL, et al. IL-17RA-signaling in Lgr5 intestinal stem cells induces expression of transcription factor ATOH1 to promote secretory cell lineage commitment. Immunity. PMID 35081371 DOI: 10.1016/j.immuni.2021.12.016 |
0.605 |
|
| 2021 |
Bechara R, Amatya N, Majumder S, Zhou C, Li Y, Liu Q, McGeachy MJ, Gaffen SL. The RNA binding protein IMP2 drives a stromal-Th17 cell circuit in autoimmune neuroinflammation. Jci Insight. PMID 34914635 DOI: 10.1172/jci.insight.152766 |
0.855 |
|
| 2021 |
Bechara R, Gaffen SL. '(m)A' stands for 'autoimmunity': reading, writing, and erasing RNA modifications during inflammation. Trends in Immunology. 42: 1073-1076. PMID 34728144 DOI: 10.1016/j.it.2021.10.002 |
0.685 |
|
| 2021 |
Phan QT, Lin J, Solis NV, Eng M, Swidergall M, Wang F, Li S, Gaffen SL, Chou TF, Filler SG. The Globular C1q Receptor Is Required for Epidermal Growth Factor Receptor Signaling during Candida albicans Infection. Mbio. e0271621. PMID 34724825 DOI: 10.1128/mBio.02716-21 |
0.598 |
|
| 2021 |
Zhou C, Wu D, Jawale C, Li Y, Biswas PS, McGeachy MJ, Gaffen SL. Divergent functions of IL-17-family cytokines in DSS colitis: Insights from a naturally-occurring human mutation in IL-17F. Cytokine. 148: 155715. PMID 34587561 DOI: 10.1016/j.cyto.2021.155715 |
0.661 |
|
| 2021 |
Li DD, Bechara R, Ramani K, Jawale CV, Li Y, Kolls JK, Gaffen SL, Biswas PS. RTEC-intrinsic IL-17-driven inflammatory circuit amplifies antibody-induced glomerulonephritis and is constrained by Regnase-1. Jci Insight. 6. PMID 34236049 DOI: 10.1172/jci.insight.147505 |
0.873 |
|
| 2021 |
Bechara R, Amatya N, Bailey RD, Li Y, Aggor FEY, Li DD, Jawale CV, Coleman BM, Dai N, Gokhale NS, Taylor TC, Horner SM, Poholek AC, Bansal A, Biswas PS, ... Gaffen SL, et al. The mA reader IMP2 directs autoimmune inflammation through an IL-17- and TNFα-dependent C/EBP transcription factor axis. Science Immunology. 6. PMID 34215679 DOI: 10.1126/sciimmunol.abd1287 |
0.881 |
|
| 2021 |
Pacheco CMF, Maltos KLM, Shehabeldin MS, Thomas LL, Zhuang Z, Yoshizawa S, Verdelis K, Gaffen SL, Garlet GP, Little SR, Sfeir C. Local Sustained Delivery of Anti-IL-17A Antibodies Limits Inflammatory Bone Loss in Murine Experimental Periodontitis. Journal of Immunology (Baltimore, Md. : 1950). 206: 2386-2392. PMID 33952619 DOI: 10.4049/jimmunol.2001432 |
0.536 |
|
| 2021 |
Bechara R, McGeachy MJ, Gaffen SL. The metabolism-modulating activity of IL-17 signaling in health and disease. The Journal of Experimental Medicine. 218. PMID 33822846 DOI: 10.1084/jem.20202191 |
0.857 |
|
| 2020 |
Zhou C, Monin L, Gordon R, Aggor FEY, Bechara R, Edwards TN, Kaplan DH, Gingras S, Gaffen SL. An IL-17F.S65L Knock-In Mouse Reveals Similarities and Differences in IL-17F Function in Oral Candidiasis: A New Tool to Understand IL-17F. Journal of Immunology (Baltimore, Md. : 1950). PMID 32601099 DOI: 10.4049/Jimmunol.2000394 |
0.895 |
|
| 2020 |
Jawale CV, Ramani K, Li DD, Coleman BM, Oberoi RS, Kupul S, Lin L, Desai JV, Delgoffe GM, Lionakis MS, Bender FH, Prokopienko AJ, Nolin TD, Gaffen SL, Biswas PS. Restoring glucose uptake rescues neutrophil dysfunction and protects against systemic fungal infection in mouse models of kidney disease. Science Translational Medicine. 12. PMID 32554707 DOI: 10.1126/Scitranslmed.Aay5691 |
0.764 |
|
| 2020 |
Aggor FEY, Break TJ, Trevejo-Nuñez G, Whibley N, Coleman BM, Bailey RD, Kaplan DH, Naglik JR, Shan W, Shetty AC, McCracken C, Durum SK, Biswas PS, Bruno VM, Kolls JK, ... ... Gaffen SL, et al. Oral epithelial IL-22/STAT3 signaling licenses IL-17-mediated immunity to oral mucosal candidiasis. Science Immunology. 5. PMID 32503875 DOI: 10.1126/Sciimmunol.Aba0570 |
0.905 |
|
| 2020 |
Gaffen SL, Moutsopoulos NM. Regulation of host-microbe interactions at oral mucosal barriers by type 17 immunity. Science Immunology. 5. PMID 31901072 DOI: 10.1126/Sciimmunol.Aau4594 |
0.58 |
|
| 2019 |
Peters BM, Coleman BM, Willems HME, Barker KS, Aggor FEY, Cipolla E, Verma AH, Bishu S, Huppler AH, Bruno VM, Gaffen SL. The IL-17R/IL-22R signaling axis is dispensable for vulvovaginal candidiasis regardless of estrogen status. The Journal of Infectious Diseases. PMID 31805183 DOI: 10.1093/Infdis/Jiz649 |
0.907 |
|
| 2019 |
Li X, Bechara R, Zhao J, McGeachy MJ, Gaffen SL. IL-17 receptor-based signaling and implications for disease. Nature Immunology. 20: 1594-1602. PMID 31745337 DOI: 10.1038/S41590-019-0514-Y |
0.884 |
|
| 2019 |
Trevejo-Nunez G, Elsegeiny W, Aggor FEY, Tweedle JL, Kaplan Z, Gandhi P, Castillo P, Ferguson A, Alcorn JF, Chen K, Kolls JK, Gaffen SL. IL-22 Binding Protein Constrains IL-22 Activity, Host Defense and Oxidative Phosphorylation Genes during Pneumococcal Pneumonia. Infection and Immunity. PMID 31451621 DOI: 10.1128/Iai.00550-19 |
0.891 |
|
| 2019 |
Naglik JR, Gaffen SL, Hube B. Candidalysin: discovery and function in Candida albicans infections. Current Opinion in Microbiology. 52: 100-109. PMID 31288097 DOI: 10.1016/J.Mib.2019.06.002 |
0.631 |
|
| 2019 |
Ho J, Yang X, Nikou SA, Kichik N, Donkin A, Ponde NO, Richardson JP, Gratacap RL, Archambault LS, Zwirner CP, Murciano C, Henley-Smith R, Thavaraj S, Tynan CJ, Gaffen SL, et al. Candidalysin activates innate epithelial immune responses via epidermal growth factor receptor. Nature Communications. 10: 2297. PMID 31127085 DOI: 10.1038/S41467-019-09915-2 |
0.617 |
|
| 2019 |
Aggor FEY, Way SS, Gaffen SL. Fungus Among Us: The Frenemies Within. Trends in Immunology. PMID 31053496 DOI: 10.1016/J.It.2019.04.007 |
0.796 |
|
| 2019 |
McGeachy MJ, Cua DJ, Gaffen SL. The IL-17 Family of Cytokines in Health and Disease. Immunity. 50: 892-906. PMID 30995505 DOI: 10.1016/J.Immuni.2019.03.021 |
0.726 |
|
| 2019 |
Majumder S, Amatya N, Revu S, Jawale CV, Wu D, Rittenhouse N, Menk A, Kupul S, Du F, Raphael I, Bhattacharjee A, Siebenlist U, Hand TW, Delgoffe GM, Poholek AC, ... Gaffen SL, et al. IL-17 metabolically reprograms activated fibroblastic reticular cells for proliferation and survival. Nature Immunology. PMID 30962593 DOI: 10.1038/S41590-019-0367-4 |
0.888 |
|
| 2019 |
Verma AH, Gaffen SL. Dermatophyte Immune Memory Is Only Skin-Deep. The Journal of Investigative Dermatology. 139: 517-519. PMID 30797318 DOI: 10.1016/J.Jid.2018.10.022 |
0.736 |
|
| 2019 |
Shen F, Verma AH, Volk A, Jones B, Coleman BM, Loza MJ, Malaviya R, Moore B, Weinstock D, Elloso MM, Gaffen SL, Ort T. Combined Blockade of TNF-α and IL-17A Alleviates Progression of Collagen-Induced Arthritis without Causing Serious Infections in Mice. Journal of Immunology (Baltimore, Md. : 1950). PMID 30745461 DOI: 10.4049/Jimmunol.1801436 |
0.871 |
|
| 2018 |
Amatya N, Childs EE, Cruz JA, Aggor FEY, Garg AV, Berman AJ, Gudjonsson JE, Atasoy U, Gaffen SL. IL-17 integrates multiple self-reinforcing, feed-forward mechanisms through the RNA binding protein Arid5a. Science Signaling. 11. PMID 30301788 DOI: 10.1126/Scisignal.Aat4617 |
0.885 |
|
| 2018 |
Ferguson ID, Griffin P, Michel JJ, Yano H, Gaffen SL, Mueller RG, Dvergsten JA, Piganelli JD, Rosenkranz ME, Kietz DA, Vallejo AN. T Cell Receptor-Independent, CD31/IL-17A-Driven Inflammatory Axis Shapes Synovitis in Juvenile Idiopathic Arthritis. Frontiers in Immunology. 9: 1802. PMID 30127787 DOI: 10.3389/Fimmu.2018.01802 |
0.584 |
|
| 2018 |
Verma AH, Zafar H, Ponde NO, Hepworth OW, Sihra D, Aggor FEY, Ainscough JS, Ho J, Richardson JP, Coleman BM, Hube B, Stacey M, McGeachy MJ, Naglik JR, Gaffen SL, et al. IL-36 and IL-1/IL-17 Drive Immunity to Oral Candidiasis via Parallel Mechanisms. Journal of Immunology (Baltimore, Md. : 1950). PMID 29891557 DOI: 10.4049/Jimmunol.1800515 |
0.914 |
|
| 2018 |
Richardson JP, Mogavero S, Moyes DL, Blagojevic M, Krüger T, Verma AH, Coleman BM, De La Cruz Diaz J, Schulz D, Ponde NO, Carrano G, Kniemeyer O, Wilson D, Bader O, Enoiu SI, ... ... Gaffen SL, et al. Processing of Candida albicans Ece1p Is Critical for Candidalysin Maturation and Fungal Virulence. Mbio. 9. PMID 29362237 DOI: 10.1128/Mbio.02178-17 |
0.795 |
|
| 2017 |
Cruz JA, Childs EE, Amatya N, Garg AV, Beyaert R, Kane LP, Aneskievich BJ, Ma A, Gaffen SL. Interleukin-17 signaling triggers degradation of the constitutive NF-κB inhibitor ABIN-1. Immunohorizons. 1: 133-141. PMID 30761389 DOI: 10.4049/immunohorizons.1700035 |
0.901 |
|
| 2017 |
Verma A, Gaffen SL, Swidergall M. Innate Immunity to Mucosal Candida Infections. Journal of Fungi (Basel, Switzerland). 3. PMID 29371576 DOI: 10.3390/Jof3040060 |
0.727 |
|
| 2017 |
Naglik JR, König A, Hube B, Gaffen SL. Candida albicans-epithelial interactions and induction of mucosal innate immunity. Current Opinion in Microbiology. 40: 104-112. PMID 29156234 DOI: 10.1016/J.Mib.2017.10.030 |
0.639 |
|
| 2017 |
Bichele R, Kärner J, Truusalu K, Smidt I, Mändar R, Conti HR, Gaffen SL, Peterson P, Laan M, Kisand K. IL-22 neutralizing autoantibodies impair fungal clearance in murine oropharyngeal candidiasis model. European Journal of Immunology. PMID 29150834 DOI: 10.1002/Eji.201747209 |
0.808 |
|
| 2017 |
Verma AH, Richardson JP, Zhou C, Coleman BM, Moyes DL, Ho J, Huppler AR, Ramani K, McGeachy MJ, Mufazalov IA, Waisman A, Kane LP, Biswas PS, Hube B, Naglik JR, ... Gaffen SL, et al. Oral epithelial cells orchestrate innate type 17 responses to Candida albicans through the virulence factor candidalysin. Science Immunology. 2. PMID 29101209 DOI: 10.1126/Sciimmunol.Aam8834 |
0.906 |
|
| 2017 |
Monin L, Gaffen SL. Interleukin 17 Family Cytokines: Signaling Mechanisms, Biological Activities, and Therapeutic Implications. Cold Spring Harbor Perspectives in Biology. PMID 28620097 DOI: 10.1101/Cshperspect.A028522 |
0.853 |
|
| 2017 |
Campfield BT, Eddens T, Henkel M, Majewski M, Horne W, Chaly Y, Gaffen SL, Hirsch R, Kolls JK. Follistatin-like protein 1 modulates IL-17 signaling via IL-17RC regulation in stromal cells. Immunology and Cell Biology. PMID 28377613 DOI: 10.1038/Icb.2017.26 |
0.727 |
|
| 2017 |
Solis NV, Swidergall M, Bruno VM, Gaffen SL, Filler SG. The Aryl Hydrocarbon Receptor Governs Epithelial Cell Invasion during Oropharyngeal Candidiasis. Mbio. 8. PMID 28325761 DOI: 10.1128/Mbio.00025-17 |
0.565 |
|
| 2017 |
Amatya N, Garg AV, Gaffen SL. IL-17 Signaling: The Yin and the Yang. Trends in Immunology. PMID 28254169 DOI: 10.1016/J.It.2017.01.006 |
0.913 |
|
| 2017 |
Simpson-Abelson MR, Hernandez-Mir G, Childs EE, Cruz JA, Poholek AC, Chattopadhyay A, Gaffen SL, McGeachy MJ. CCAAT/Enhancer-binding protein β promotes pathogenesis of EAE. Cytokine. 92: 24-32. PMID 28088614 DOI: 10.1016/J.Cyto.2017.01.005 |
0.847 |
|
| 2016 |
Conti HR, Bruno VM, Childs EE, Daugherty S, Hunter JP, Mengesha BG, Saevig DL, Hendricks MR, Coleman BM, Brane L, Solis N, Cruz JA, Verma AH, Garg AV, Hise AG, ... ... Gaffen SL, et al. IL-17 Receptor Signaling in Oral Epithelial Cells Is Critical for Protection against Oropharyngeal Candidiasis. Cell Host & Microbe. 20: 606-617. PMID 27923704 DOI: 10.1016/J.Chom.2016.10.001 |
0.895 |
|
| 2016 |
Chen K, Eddens T, Trevejo-Nunez G, Way EE, Elsegeiny W, Ricks DM, Garg AV, Erb CJ, Bo M, Wang T, Chen W, Lee JS, Gaffen SL, Kolls JK. IL-17 Receptor Signaling in the Lung Epithelium Is Required for Mucosal Chemokine Gradients and Pulmonary Host Defense against K. pneumoniae. Cell Host & Microbe. 20: 596-605. PMID 27923703 DOI: 10.1016/J.Chom.2016.10.003 |
0.907 |
|
| 2016 |
Monin L, Gudjonsson JE, Childs EE, Amatya N, Xing X, Verma AH, Coleman BM, Garg AV, Killeen M, Mathers A, Ward NL, Gaffen SL. MCPIP1/Regnase-1 Restricts IL-17A- and IL-17C-Dependent Skin Inflammation. Journal of Immunology (Baltimore, Md. : 1950). PMID 27920272 DOI: 10.4049/Jimmunol.1601551 |
0.896 |
|
| 2016 |
Ramani K, Garg AV, Jawale CV, Conti HR, Whibley N, Jackson EK, Shiva SS, Horne W, Kolls JK, Gaffen SL, Biswas PS. The Kallikrein-Kinin System: A Novel Mediator of IL-17-Driven Anti-Candida Immunity in the Kidney. Plos Pathogens. 12: e1005952. PMID 27814401 DOI: 10.1371/Journal.Ppat.1005952 |
0.874 |
|
| 2016 |
Huppler AR, Gaffen SL. Editorial: Fake it 'til you make it: mast cells acquire IL-17 exogenously. Journal of Leukocyte Biology. 100: 445-6. PMID 27587375 DOI: 10.1189/Jlb.3Ce0216-071R |
0.868 |
|
| 2016 |
Whibley N, Tritto E, Traggiai E, Kolbinger F, Moulin P, Brees D, Coleman BM, Mamo AJ, Garg AV, Jaycox JR, Siebenlist U, Kammüller M, Gaffen SL. Antibody blockade of IL-17 family cytokines in immunity to acute murine oral mucosal candidiasis. Journal of Leukocyte Biology. PMID 26729813 DOI: 10.1189/Jlb.4A0915-428R |
0.906 |
|
| 2015 |
Gaffen S. IL-17 receptor composition. Nature Reviews. Immunology. 16: 4. PMID 26593717 DOI: 10.1038/Nri.2015.2 |
0.578 |
|
| 2015 |
Whibley N, Gaffen SL. Gut-Busters: IL-17 Ain't Afraid of No IL-23. Immunity. 43: 620-2. PMID 26488809 DOI: 10.1016/J.Immuni.2015.10.001 |
0.89 |
|
| 2015 |
Whibley N, Jaycox JR, Reid D, Garg AV, Taylor JA, Clancy CJ, Nguyen MH, Biswas PS, McGeachy MJ, Brown GD, Gaffen SL. Delinking CARD9 and IL-17: CARD9 Protects against Candida tropicalis Infection through a TNF-α-Dependent, IL-17-Independent Mechanism. Journal of Immunology (Baltimore, Md. : 1950). 195: 3781-92. PMID 26336150 DOI: 10.4049/Jimmunol.1500870 |
0.868 |
|
| 2015 |
Garg AV, Amatya N, Chen K, Cruz JA, Grover P, Whibley N, Conti HR, Hernandez Mir G, Sirakova T, Childs EC, Smithgall TE, Biswas PS, Kolls JK, McGeachy MJ, Kolattukudy PE, ... Gaffen SL, et al. MCPIP1 Endoribonuclease Activity Negatively Regulates Interleukin-17-Mediated Signaling and Inflammation. Immunity. 43: 475-87. PMID 26320658 DOI: 10.1016/J.Immuni.2015.07.021 |
0.902 |
|
| 2015 |
Simpson-Abelson MR, Childs EE, Ferreira MC, Bishu S, Conti HR, Gaffen SL. C/EBPβ Promotes Immunity to Oral Candidiasis through Regulation of β-Defensins. Plos One. 10: e0136538. PMID 26317211 DOI: 10.1371/Journal.Pone.0136538 |
0.877 |
|
| 2015 |
Whibley N, Gaffen SL. Beyond Candida albicans: Mechanisms of immunity to non-albicans Candida species. Cytokine. 76: 42-52. PMID 26276374 DOI: 10.1016/J.Cyto.2015.07.025 |
0.744 |
|
| 2015 |
Huppler AR, Verma AH, Conti HR, Gaffen SL. Neutrophils Do Not Express IL-17A in the Context of Acute Oropharyngeal Candidiasis. Pathogens (Basel, Switzerland). 4: 559-72. PMID 26213975 DOI: 10.3390/Pathogens4030559 |
0.914 |
|
| 2015 |
Conti HR, Gaffen SL. IL-17-Mediated Immunity to the Opportunistic Fungal Pathogen Candida albicans. Journal of Immunology (Baltimore, Md. : 1950). 195: 780-8. PMID 26188072 DOI: 10.4049/Jimmunol.1500909 |
0.883 |
|
| 2015 |
Huppler AR, Whibley N, Woolford CA, Childs EE, He J, Biswas PS, McGeachy MJ, Mitchell AP, Gaffen SL. A Candida albicans strain expressing mammalian IL-17A results in early control of fungal growth during disseminated infection. Infection and Immunity. PMID 26150537 DOI: 10.1128/Iai.03057-14 |
0.879 |
|
| 2015 |
Conti HR, Whibley N, Coleman BM, Garg AV, Jaycox JR, Gaffen SL. Signaling through IL-17C/IL-17RE is dispensable for immunity to systemic, oral and cutaneous candidiasis. Plos One. 10: e0122807. PMID 25849644 DOI: 10.1371/Journal.Pone.0122807 |
0.914 |
|
| 2015 |
Gaffen SL, McGeachy MJ. Integrating p38α MAPK immune signals in nonimmune cells. Science Signaling. 8: fs5. PMID 25737584 DOI: 10.1126/Scisignal.Aaa8398 |
0.332 |
|
| 2015 |
Huppler AR, Conti HR, Hernández-Santos N, Darville T, Biswas PS, Gaffen SL. Correction: Role of Neutrophils in IL-17-Dependent Immunity to Mucosal Candidiasis. Journal of Immunology (Baltimore, Md. : 1950). 194: 1382. PMID 25596301 DOI: 10.4049/Jimmunol.1490053 |
0.856 |
|
| 2015 |
Drummond RA, Gaffen SL, Hise AG, Brown GD. Innate Defense against Fungal Pathogens. Cold Spring Harbor Perspectives in Medicine. 5. PMID 25384766 DOI: 10.1101/Cshperspect.A019620 |
0.455 |
|
| 2015 |
Agustin Cruz J, Garg AV, Amatya N, Ma A, Gaffen SL. ID: 179 Cytokine. 76: 97. DOI: 10.1016/J.Cyto.2015.08.189 |
0.908 |
|
| 2015 |
Ramani K, Garg A, Conti H, Whibley N, Kolls J, Gaffen S, Biswas P. ID: 44 Cytokine. 76: 72. DOI: 10.1016/J.Cyto.2015.08.074 |
0.888 |
|
| 2015 |
Garg A, Amatya N, Chen K, Agustin Cruz J, Grover P, Whibley N, Conti HR, Mir GH, Sirakova T, Childs EC, Smithgall TE, Biswas PS, Kolls JK, McGeachy MJ, Kolattukudy PE, ... Gaffen SL, et al. ID: 36 Cytokine. 76: 70. DOI: 10.1016/J.Cyto.2015.08.066 |
0.912 |
|
| 2015 |
Gaffen S. ID: 154 Cytokine. 76: 64-65. DOI: 10.1016/J.Cyto.2015.08.041 |
0.736 |
|
| 2014 |
Whibley N, Gaffen SL. Brothers in arms: Th17 and Treg responses in Candida albicans immunity. Plos Pathogens. 10: e1004456. PMID 25474407 DOI: 10.1371/Journal.Ppat.1004456 |
0.845 |
|
| 2014 |
Conti HR, Peterson AC, Brane L, Huppler AR, Hernández-Santos N, Whibley N, Garg AV, Simpson-Abelson MR, Gibson GA, Mamo AJ, Osborne LC, Bishu S, Ghilardi N, Siebenlist U, Watkins SC, ... ... Gaffen SL, et al. Oral-resident natural Th17 cells and γδ T cells control opportunistic Candida albicans infections. The Journal of Experimental Medicine. 211: 2075-84. PMID 25200028 DOI: 10.1084/Jem.20130877 |
0.882 |
|
| 2014 |
Gaffen SL, Jain R, Garg AV, Cua DJ. The IL-23-IL-17 immune axis: from mechanisms to therapeutic testing. Nature Reviews. Immunology. 14: 585-600. PMID 25145755 DOI: 10.1038/Nri3707 |
0.816 |
|
| 2014 |
Ramani K, Pawaria S, Maers K, Huppler AR, Gaffen SL, Biswas PS. An essential role of interleukin-17 receptor signaling in the development of autoimmune glomerulonephritis. Journal of Leukocyte Biology. 96: 463-72. PMID 24935958 DOI: 10.1189/Jlb.3A0414-184R |
0.857 |
|
| 2014 |
Conti HR, Huppler AR, Whibley N, Gaffen SL. Animal models for candidiasis. Current Protocols in Immunology / Edited by John E. Coligan ... [Et Al.]. 105: 19.6.1-17. PMID 24700323 DOI: 10.1002/0471142735.Im1906S105 |
0.762 |
|
| 2014 |
Bishu S, Su EW, Wilkerson ER, Reckley KA, Jones DM, McGeachy MJ, Gaffen SL, Levesque MC. Rheumatoid arthritis patients exhibit impaired Candida albicans-specific Th17 responses. Arthritis Research & Therapy. 16: R50. PMID 24513269 DOI: 10.1186/Ar4480 |
0.813 |
|
| 2014 |
Huppler AR, Conti HR, Hernández-Santos N, Darville T, Biswas PS, Gaffen SL. Role of neutrophils in IL-17-dependent immunity to mucosal candidiasis. Journal of Immunology (Baltimore, Md. : 1950). 192: 1745-52. PMID 24442441 DOI: 10.4049/Jimmunol.1302265 |
0.911 |
|
| 2014 |
Whibley N, Maccallum DM, Vickers MA, Zafreen S, Waldmann H, Hori S, Gaffen SL, Gow NA, Barker RN, Hall AM. Expansion of Foxp3(+) T-cell populations by Candida albicans enhances both Th17-cell responses and fungal dissemination after intravenous challenge. European Journal of Immunology. 44: 1069-83. PMID 24435677 DOI: 10.1002/Eji.201343604 |
0.797 |
|
| 2014 |
Bishu S, Hernández-Santos N, Simpson-Abelson MR, Huppler AR, Conti HR, Ghilardi N, Mamo AJ, Gaffen SL. The adaptor CARD9 is required for adaptive but not innate immunity to oral mucosal Candida albicans infections. Infection and Immunity. 82: 1173-80. PMID 24379290 DOI: 10.1128/Iai.01335-13 |
0.901 |
|
| 2014 |
Ferreira MC, Whibley N, Mamo AJ, Siebenlist U, Chan YR, Gaffen SL. Interleukin-17-induced protein lipocalin 2 is dispensable for immunity to oral candidiasis. Infection and Immunity. 82: 1030-5. PMID 24343647 DOI: 10.1128/Iai.01389-13 |
0.874 |
|
| 2013 |
Garg AV, Gaffen SL. IL-17 signaling and A20: a balancing act. Cell Cycle (Georgetown, Tex.). 12: 3459-60. PMID 24107622 DOI: 10.4161/Cc.26699 |
0.789 |
|
| 2013 |
Ho AW, Garg AV, Monin L, Simpson-Abelson MR, Kinner L, Gaffen SL. The anaphase-promoting complex protein 5 (AnapC5) associates with A20 and inhibits IL-17-mediated signal transduction. Plos One. 8: e70168. PMID 23922952 DOI: 10.1371/Journal.Pone.0070168 |
0.911 |
|
| 2013 |
Garg AV, Ahmed M, Vallejo AN, Ma A, Gaffen SL. The deubiquitinase A20 mediates feedback inhibition of interleukin-17 receptor signaling. Science Signaling. 6: ra44. PMID 23737552 DOI: 10.1126/Scisignal.2003699 |
0.863 |
|
| 2013 |
Ahmed M, Gaffen SL. IL-17 inhibits adipogenesis in part via C/EBPα, PPARγ and Krüppel-like factors. Cytokine. 61: 898-905. PMID 23332504 DOI: 10.1016/J.Cyto.2012.12.007 |
0.831 |
|
| 2013 |
Hernández-Santos N, Huppler AR, Peterson AC, Khader SA, McKenna KC, Gaffen SL. Th17 cells confer long-term adaptive immunity to oral mucosal Candida albicans infections. Mucosal Immunology. 6: 900-10. PMID 23250275 DOI: 10.1038/Mi.2012.128 |
0.867 |
|
| 2013 |
Whibley N, Mamo AJ, Traggiai E, Kolbinger F, Vogel B, Kammüller M, Siebenlist U, Gaffen SL. 279 Cytokine. 63: 309. DOI: 10.1016/J.Cyto.2013.06.282 |
0.898 |
|
| 2013 |
Sheehan RP, Garg A, Gaffen SL, Faeder JR. 236 Cytokine. 63: 299. DOI: 10.1016/J.Cyto.2013.06.239 |
0.728 |
|
| 2013 |
Huppler AR, Hernández-Santos N, Conti HR, Gaffen SL. 124 Cytokine. 63: 272. DOI: 10.1016/J.Cyto.2013.06.127 |
0.896 |
|
| 2012 |
Huppler AR, Bishu S, Gaffen SL. Mucocutaneous candidiasis: the IL-17 pathway and implications for targeted immunotherapy. Arthritis Research & Therapy. 14: 217. PMID 22838497 DOI: 10.1186/Ar3893 |
0.909 |
|
| 2012 |
Hernández-Santos N, Gaffen SL. Th17 cells in immunity to Candida albicans. Cell Host & Microbe. 11: 425-35. PMID 22607796 DOI: 10.1016/J.Chom.2012.04.008 |
0.831 |
|
| 2012 |
Dasa V, Kramer JM, Gaffen SL, Kirkwood KL, Mihalko WM. Is monocyte chemotactic protein 1 elevated in aseptic loosening of TKA? A pilot study. Clinical Orthopaedics and Related Research. 470: 1879-84. PMID 22131127 DOI: 10.1007/S11999-011-2191-5 |
0.657 |
|
| 2012 |
Garg A, Ahmed M, Childs E, Ma A, Gaffen S. P069 Inhibition of IL-17 receptor signal transduction Cytokine. 59: 541. DOI: 10.1016/J.Cyto.2012.06.155 |
0.905 |
|
| 2011 |
Gaffen SL. Life before seventeen: cloning of the IL-17 receptor. Journal of Immunology (Baltimore, Md. : 1950). 187: 4389-91. PMID 22013204 DOI: 10.4049/Jimmunol.1102576 |
0.501 |
|
| 2011 |
Gaffen SL. Recent advances in the IL-17 cytokine family. Current Opinion in Immunology. 23: 613-9. PMID 21852080 DOI: 10.1016/J.Coi.2011.07.006 |
0.709 |
|
| 2011 |
Joshi S, Pantalena LC, Liu XK, Gaffen SL, Liu H, Rohowsky-Kochan C, Ichiyama K, Yoshimura A, Steinman L, Christakos S, Youssef S. 1,25-dihydroxyvitamin D(3) ameliorates Th17 autoimmunity via transcriptional modulation of interleukin-17A. Molecular and Cellular Biology. 31: 3653-69. PMID 21746882 DOI: 10.1128/Mcb.05020-11 |
0.746 |
|
| 2011 |
Gaffen SL, Hernández-Santos N, Peterson AC. IL-17 signaling in host defense against Candida albicans. Immunologic Research. 50: 181-7. PMID 21717069 DOI: 10.1007/S12026-011-8226-X |
0.834 |
|
| 2011 |
Myneni SR, Settem RP, Connell TD, Keegan AD, Gaffen SL, Sharma A. TLR2 signaling and Th2 responses drive Tannerella forsythia-induced periodontal bone loss. Journal of Immunology (Baltimore, Md. : 1950). 187: 501-9. PMID 21632710 DOI: 10.4049/Jimmunol.1100683 |
0.424 |
|
| 2011 |
Pandiyan P, Conti HR, Zheng L, Peterson AC, Mathern DR, Hernández-Santos N, Edgerton M, Gaffen SL, Lenardo MJ. CD4(+)CD25(+)Foxp3(+) regulatory T cells promote Th17 cells in vitro and enhance host resistance in mouse Candida albicans Th17 cell infection model. Immunity. 34: 422-34. PMID 21435589 DOI: 10.1016/J.Immuni.2011.03.002 |
0.875 |
|
| 2011 |
Conti HR, Baker O, Freeman AF, Jang WS, Holland SM, Li RA, Edgerton M, Gaffen SL. New mechanism of oral immunity to mucosal candidiasis in hyper-IgE syndrome. Mucosal Immunology. 4: 448-55. PMID 21346738 DOI: 10.1038/Mi.2011.5 |
0.855 |
|
| 2011 |
Gaffen S, Ho AW, Onishi R, Shen F, Peterson A, Hernández-Santos N, Garg A, Ouyang W, Childs EE. CS11-2. Signaling by the IL-17RA/IL-17RC Complex: Impact on oral mucosal immunity Cytokine. 56: 60. DOI: 10.1016/J.Cyto.2011.07.370 |
0.889 |
|
| 2011 |
Simpson-Abelson M, Shen F, Gaffen S. PS2-042. IL-17-mediated regulation of C/EBPβ alternative translation: Implications for signaling and response to infection Cytokine. 56: 74. DOI: 10.1016/J.Cyto.2011.07.202 |
0.887 |
|
| 2011 |
Hernandez-Santos N, Peterson AC, Gaffen S. PS1-037. Cellular mediators of long-term protective immunity to Candida albicans in oropharyngeal candidiasis Cytokine. 56: 26. DOI: 10.1016/J.Cyto.2011.07.057 |
0.736 |
|
| 2010 |
Ahmed M, Gaffen SL. IL-17 in obesity and adipogenesis. Cytokine & Growth Factor Reviews. 21: 449-53. PMID 21084215 DOI: 10.1016/J.Cytogfr.2010.10.005 |
0.775 |
|
| 2010 |
Onishi RM, Park SJ, Hanel W, Ho AW, Maitra A, Gaffen SL. SEF/IL-17R (SEFIR) is not enough: an extended SEFIR domain is required for il-17RA-mediated signal transduction. The Journal of Biological Chemistry. 285: 32751-9. PMID 20729198 DOI: 10.1074/Jbc.M110.121418 |
0.902 |
|
| 2010 |
Ho AW, Shen F, Conti HR, Patel N, Childs EE, Peterson AC, Hernández-Santos N, Kolls JK, Kane LP, Ouyang W, Gaffen SL. IL-17RC is required for immune signaling via an extended SEF/IL-17R signaling domain in the cytoplasmic tail. Journal of Immunology (Baltimore, Md. : 1950). 185: 1063-70. PMID 20554964 DOI: 10.4049/Jimmunol.0903739 |
0.908 |
|
| 2010 |
Onishi RM, Gaffen SL. Interleukin-17 and its target genes: mechanisms of interleukin-17 function in disease. Immunology. 129: 311-21. PMID 20409152 DOI: 10.1111/J.1365-2567.2009.03240.X |
0.905 |
|
| 2010 |
Conti HR, Gaffen SL. Host responses to Candida albicans: Th17 cells and mucosal candidiasis. Microbes and Infection / Institut Pasteur. 12: 518-27. PMID 20381638 DOI: 10.1016/J.Micinf.2010.03.013 |
0.728 |
|
| 2010 |
Segal BH, Han W, Bushey JJ, Joo M, Bhatti Z, Feminella J, Dennis CG, Vethanayagam RR, Yull FE, Capitano M, Wallace PK, Minderman H, Christman JW, Sporn MB, Chan J, ... ... Gaffen SL, et al. NADPH oxidase limits innate immune responses in the lungs in mice. Plos One. 5: e9631. PMID 20300512 DOI: 10.1371/Journal.Pone.0009631 |
0.307 |
|
| 2010 |
Feinen B, Jerse AE, Gaffen SL, Russell MW. Critical role of Th17 responses in a murine model of Neisseria gonorrhoeae genital infection Mucosal Immunology. 3: 312-321. PMID 20107432 DOI: 10.1038/Mi.2009.139 |
0.719 |
|
| 2010 |
Ho AW, Gaffen SL. IL-17RC: a partner in IL-17 signaling and beyond. Seminars in Immunopathology. 32: 33-42. PMID 20012905 DOI: 10.1007/S00281-009-0185-0 |
0.863 |
|
| 2010 |
Gaffen SL, Onishi RM, Park SJ, Ho AW, Maitra A, Hanel W, Shen F. CS6-1 A SEFIR is not enough: Structure and function in the IL-17 receptor superfamily Cytokine. 52: 72. DOI: 10.1016/J.Cyto.2010.07.301 |
0.869 |
|
| 2010 |
Ahmed M, Goswami J, Hernández-Santos N, Gaffen SL. PS2-29 IL-17 and its Jekyll-and-Hyde role in the regulation of fat and bone Cytokine. 52: 56. DOI: 10.1016/J.Cyto.2010.07.234 |
0.869 |
|
| 2010 |
Ho AW, Shen F, Conti HR, Patel N, Peterson A, Hernández-Santos N, K. Kolls J, Kane L, Ouyang W, Childs EE, Gaffen SL. SS2-4 Molecular and cellular contributions of IL-17RC to IL-17 signaling and host defense against fungal infections Cytokine. 52: 13-14. DOI: 10.1016/J.Cyto.2010.07.059 |
0.899 |
|
| 2009 |
Lin Y, Ritchea S, Logar A, Slight S, Messmer M, Rangel-Moreno J, Guglani L, Alcorn JF, Strawbridge H, Park SM, Onishi R, Nyugen N, Walter MJ, Pociask D, Randall TD, ... Gaffen SL, et al. Interleukin-17 is required for T helper 1 cell immunity and host resistance to the intracellular pathogen Francisella tularensis. Immunity. 31: 799-810. PMID 19853481 DOI: 10.1016/J.Immuni.2009.08.025 |
0.912 |
|
| 2009 |
Durrant DM, Gaffen SL, Riesenfeld EP, Irvin CG, Metzger DW. Development of allergen-induced airway inflammation in the absence of T-bet regulation is dependent on IL-17. Journal of Immunology (Baltimore, Md. : 1950). 183: 5293-300. PMID 19783683 DOI: 10.4049/Jimmunol.0803109 |
0.522 |
|
| 2009 |
Gaffen SL. The role of interleukin-17 in the pathogenesis of rheumatoid arthritis. Current Rheumatology Reports. 11: 365-70. PMID 19772832 DOI: 10.1007/S11926-009-0052-Y |
0.722 |
|
| 2009 |
Goswami J, Hernández-Santos N, Zuniga LA, Gaffen SL. A bone-protective role for IL-17 receptor signaling in ovariectomy-induced bone loss. European Journal of Immunology. 39: 2831-9. PMID 19731364 DOI: 10.1002/Eji.200939670 |
0.864 |
|
| 2009 |
Khader SA, Gaffen SL, Kolls JK. Th17 cells at the crossroads of innate and adaptive immunity against infectious diseases at the mucosa Mucosal Immunology. 2: 403-411. PMID 19587639 DOI: 10.1038/Mi.2009.100 |
0.711 |
|
| 2009 |
Gaffen SL. Structure and signalling in the IL-17 receptor family. Nature Reviews. Immunology. 9: 556-67. PMID 19575028 DOI: 10.1038/Nri2586 |
0.65 |
|
| 2009 |
Lu YC, Kim I, Lye E, Shen F, Suzuki N, Suzuki S, Gerondakis S, Akira S, Gaffen SL, Yeh WC, Ohashi PS. Differential role for c-Rel and C/EBPbeta/delta in TLR-mediated induction of proinflammatory cytokines. Journal of Immunology (Baltimore, Md. : 1950). 182: 7212-21. PMID 19454718 DOI: 10.4049/Jimmunol.0802971 |
0.723 |
|
| 2009 |
Shen F, Li N, Gade P, Kalvakolanu DV, Weibley T, Doble B, Woodgett JR, Wood TD, Gaffen SL. IL-17 receptor signaling inhibits C/EBPbeta by sequential phosphorylation of the regulatory 2 domain. Science Signaling. 2: ra8. PMID 19244213 DOI: 10.1126/scisignal.2000066 |
0.756 |
|
| 2009 |
Conti HR, Shen F, Nayyar N, Stocum E, Sun JN, Lindemann MJ, Ho AW, Hai JH, Yu JJ, Jung JW, Filler SG, Masso-Welch P, Edgerton M, Gaffen SL. Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis. The Journal of Experimental Medicine. 206: 299-311. PMID 19204111 DOI: 10.1084/Jem.20081463 |
0.905 |
|
| 2009 |
Gaffen SL. Erratum: Structure and signalling in the IL-17 receptor family Nature Reviews Immunology. 9: 747-747. DOI: 10.1038/Nri2625 |
0.504 |
|
| 2009 |
Gaffen SL, Conti HR, Shen F, Nayyar N, Stocum E, Sun J, Lindemann MJ, Ho A, Hai JH, Masso-Welch P. Th17/IL-17 receptor signaling and not Th1 cells are essential for mucosal host defense against oral candidiasis Cytokine. 48: 43. DOI: 10.1016/J.Cyto.2009.07.361 |
0.878 |
|
| 2008 |
Gaffen SL, Hajishengallis G. A new inflammatory cytokine on the block: re-thinking periodontal disease and the Th1/Th2 paradigm in the context of Th17 cells and IL-17. Journal of Dental Research. 87: 817-28. PMID 18719207 DOI: 10.1177/154405910808700908 |
0.408 |
|
| 2008 |
Gaffen SL. An overview of IL-17 function and signaling. Cytokine. 43: 402-7. PMID 18701318 DOI: 10.1016/j.cyto.2008.07.017 |
0.608 |
|
| 2008 |
Yu JJ, Ruddy MJ, Conti HR, Boonanantanasarn K, Gaffen SL. The interleukin-17 receptor plays a gender-dependent role in host protection against Porphyromonas gingivalis-induced periodontal bone loss. Infection and Immunity. 76: 4206-13. PMID 18591228 DOI: 10.1128/Iai.01209-07 |
0.884 |
|
| 2008 |
Lindemann MJ, Hu Z, Benczik M, Liu KD, Gaffen SL. Differential regulation of the IL-17 receptor by gammac cytokines: inhibitory signaling by the phosphatidylinositol 3-kinase pathway. The Journal of Biological Chemistry. 283: 14100-8. PMID 18348982 DOI: 10.1074/Jbc.M801357200 |
0.912 |
|
| 2008 |
Shen F, Gaffen SL. Structure-function relationships in the IL-17 receptor: implications for signal transduction and therapy. Cytokine. 41: 92-104. PMID 18178098 DOI: 10.1016/J.Cyto.2007.11.013 |
0.748 |
|
| 2008 |
Yu JJ, Gaffen SL. Interleukin-17: a novel inflammatory cytokine that bridges innate and adaptive immunity. Frontiers in Bioscience : a Journal and Virtual Library. 13: 170-7. PMID 17981535 DOI: 10.2741/2667 |
0.851 |
|
| 2008 |
Shen F, Li N, Wood T, Gaffen SL. 353 IL-17 signaling induces sequential phosphorylation of C/EBPβ Cytokine. 43: 327. DOI: 10.1016/J.Cyto.2008.07.438 |
0.761 |
|
| 2008 |
Gaffen SL. SY-13 Structure and function of the IL-17 receptor Cytokine. 43: 279. DOI: 10.1016/J.Cyto.2008.07.226 |
0.616 |
|
| 2008 |
Conti HR, Shen F, Nayyar N, Stocum E, Lindemann MJ, Ho A, Masso-Welch P, Edgerton M, Gaffen SL. 52 Defining host T-cell responses in oral candidiasis Cytokine. 43: 249. DOI: 10.1016/J.Cyto.2008.07.093 |
0.772 |
|
| 2007 |
Kramer JM, Hanel W, Shen F, Isik N, Malone JP, Maitra A, Sigurdson W, Swart D, Tocker J, Jin T, Gaffen SL. Cutting edge: identification of a pre-ligand assembly domain (PLAD) and ligand binding site in the IL-17 receptor. Journal of Immunology (Baltimore, Md. : 1950). 179: 6379-83. PMID 17982023 DOI: 10.4049/Jimmunol.179.10.6379 |
0.868 |
|
| 2007 |
Kramer JM, Gaffen SL. Interleukin-17: a new paradigm in inflammation, autoimmunity, and therapy. Journal of Periodontology. 78: 1083-93. PMID 17539723 DOI: 10.1902/Jop.2007.060392 |
0.804 |
|
| 2007 |
Maitra A, Shen F, Hanel W, Mossman K, Tocker J, Swart D, Gaffen SL. Distinct functional motifs within the IL-17 receptor regulate signal transduction and target gene expression. Proceedings of the National Academy of Sciences of the United States of America. 104: 7506-11. PMID 17456598 DOI: 10.1016/J.Cyto.2007.07.143 |
0.875 |
|
| 2007 |
Khader SA, Bell GK, Pearl JE, Fountain JJ, Rangel-Moreno J, Cilley GE, Shen F, Eaton SM, Gaffen SL, Swain SL, Locksley RM, Haynes L, Randall TD, Cooper AM. IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge. Nature Immunology. 8: 369-77. PMID 17351619 DOI: 10.1038/Ni1449 |
0.663 |
|
| 2007 |
Yu JJ, Ruddy MJ, Wong GC, Sfintescu C, Baker PJ, Smith JB, Evans RT, Gaffen SL. An essential role for IL-17 in preventing pathogen-initiated bone destruction: recruitment of neutrophils to inflamed bone requires IL-17 receptor-dependent signals. Blood. 109: 3794-802. PMID 17202320 DOI: 10.1182/Blood-2005-09-010116 |
0.877 |
|
| 2007 |
Kramer JM, Yi L, Shen F, Maitra A, Jiao X, Jin T, Gaffen SL. Cutting edge: evidence for ligand-independent multimerization of the IL-17 receptor The Journal of Immunology. 179: 8569.2-8569. DOI: 10.4049/jimmunol.179.12.8569-a |
0.868 |
|
| 2007 |
Maitra A, Gaffen SL. IL-17F, a target for anti-cytokine therapy Expert Opinion On Therapeutic Patents. 17: 453-458. DOI: 10.1517/13543776.17.4.453 |
0.821 |
|
| 2007 |
Kramer JM, Hanel W, Shen F, Isik N, Malone JP, Maitra A, Sigurdson W, Swart D, Tocker J, Jin T, Gaffen SL. 78 Dissecting the IL-17 Receptor: Identification of a Pre-ligand Assembly Domain (PLAD) and Ligand Binding Site in IL-17RA Cytokine. 39: 22. DOI: 10.1016/J.Cyto.2007.07.083 |
0.873 |
|
| 2006 |
Gaffen SL, Kramer JM, Yu JJ, Shen F. The IL-17 cytokine family. Vitamins and Hormones. 74: 255-82. PMID 17027518 DOI: 10.1016/S0083-6729(06)74010-9 |
0.91 |
|
| 2006 |
Shen F, Hu Z, Goswami J, Gaffen SL. Identification of common transcriptional regulatory elements in interleukin-17 target genes. The Journal of Biological Chemistry. 281: 24138-48. PMID 16798734 DOI: 10.1074/Jbc.M604597200 |
0.786 |
|
| 2006 |
Kramer JM, Yi L, Shen F, Maitra A, Jiao X, Jin T, Gaffen SL. Evidence for ligand-independent multimerization of the IL-17 receptor. Journal of Immunology (Baltimore, Md. : 1950). 176: 711-5. PMID 16393951 DOI: 10.4049/Jimmunol.176.2.711 |
0.906 |
|
| 2005 |
Liu XK, Clements JL, Gaffen SL. Signaling through the murine T cell receptor induces IL-17 production in the absence of costimulation, IL-23 or dendritic cells. Molecules and Cells. 20: 339-47. PMID 16404147 |
0.847 |
|
| 2005 |
Shen F, Ruddy MJ, Plamondon P, Gaffen SL. Cytokines link osteoblasts and inflammation: microarray analysis of interleukin-17- and TNF-alpha-induced genes in bone cells. Journal of Leukocyte Biology. 77: 388-99. PMID 15591425 DOI: 10.1189/Jlb.0904490 |
0.874 |
|
| 2004 |
Gaffen SL, Liu KD. Overview of interleukin-2 function, production and clinical applications. Cytokine. 28: 109-23. PMID 15473953 DOI: 10.1016/j.cyto.2004.06.010 |
0.625 |
|
| 2004 |
Liu XK, Lin X, Gaffen SL. Crucial role for nuclear factor of activated T cells in T cell receptor-mediated regulation of human interleukin-17. The Journal of Biological Chemistry. 279: 52762-71. PMID 15459204 DOI: 10.1074/jbc.M405764200 |
0.798 |
|
| 2004 |
Benczik M, Gaffen SL. The interleukin (IL)-2 family cytokines: survival and proliferation signaling pathways in T lymphocytes. Immunological Investigations. 33: 109-42. PMID 15195693 DOI: 10.1081/Imm-120030732 |
0.9 |
|
| 2004 |
Ruddy MJ, Shen F, Smith JB, Sharma A, Gaffen SL. Interleukin-17 regulates expression of the CXC chemokine LIX/CXCL5 in osteoblasts: implications for inflammation and neutrophil recruitment. Journal of Leukocyte Biology. 76: 135-44. PMID 15107456 DOI: 10.1189/Jlb.0204065 |
0.897 |
|
| 2004 |
Ruddy MJ, Wong GC, Liu XK, Yamamoto H, Kasayama S, Kirkwood KL, Gaffen SL. Functional cooperation between interleukin-17 and tumor necrosis factor-alpha is mediated by CCAAT/enhancer-binding protein family members. The Journal of Biological Chemistry. 279: 2559-67. PMID 14600152 DOI: 10.1074/Jbc.M308809200 |
0.909 |
|
| 2003 |
Lindemann MJ, Benczik M, Gaffen SL. Anti-apoptotic signaling by the interleukin-2 receptor reveals a function for cytoplasmic tyrosine residues within the common gamma (gamma c) receptor subunit. The Journal of Biological Chemistry. 278: 10239-49. PMID 12525482 DOI: 10.1074/Jbc.M209471200 |
0.897 |
|
| 2001 |
Gaffen SL. Signaling domains of the interleukin 2 receptor. Cytokine. 14: 63-77. PMID 11356007 DOI: 10.1006/cyto.2001.0862 |
0.671 |
|
| 1999 |
Gaffen SL, Lai SY, Longmore GD, Liu KD, Goldsmith MA. Genetic evidence for an additional factor required for erythropoietin- induced signal transduction Blood. 94: 74-86. PMID 10381500 DOI: 10.1182/Blood.V94.1.74.413K36_74_86 |
0.686 |
|
| 1999 |
Chan SY, Speck RF, Power C, Gaffen SL, Chesebro B, Goldsmith MA. V3 recombinants indicate a central role for CCR5 as a coreceptor in tissue infection by human immunodeficiency virus type 1 Journal of Virology. 73: 2350-2358. PMID 9971818 DOI: 10.1128/Jvi.73.3.2350-2358.1999 |
0.566 |
|
| 1998 |
Liu KD, Gaffen SL, Goldsmith MA. JAK/STAT signaling by cytokine receptors Current Opinion in Immunology. 10: 271-278. PMID 9638363 DOI: 10.1016/S0952-7915(98)80165-9 |
0.646 |
|
| 1997 |
Liu KD, Gaffen SL, Goldsmith MA, Greene WC. Janus kinases in interleukin-2-mediated signaling: JAK1 and JAK3 are differentially regulated by tyrosine phosphorylation Current Biology. 7: 817-826. PMID 9382798 DOI: 10.1016/S0960-9822(06)00369-1 |
0.75 |
|
| 1997 |
Gaffen SL, Wang S, Koshland ME. Expression of the immunoglobulin J chain in a murine B lymphoma is driven by autocrine production of interleukin 2. Cytokine. 8: 513-24. PMID 8891432 DOI: 10.1006/cyto.1996.0070 |
0.808 |
|
| 1996 |
Gaffen SL, Lai SY, Ha M, Liu X, Hennighausen L, Greene WC, Goldsmith MA. Distinct tyrosine residues within the interleukin-2 receptor beta chain drive signal transduction specificity, redundancy, and diversity. The Journal of Biological Chemistry. 271: 21381-90. PMID 8702919 DOI: 10.1074/Jbc.271.35.21381 |
0.871 |
|
| 1996 |
Lai SY, Xu W, Gaffen SL, Liu KD, Longmore GD, Greene WC, Goldsmith MA. The molecular role of the common γ subunit in signal transduction reveals functional asymmetry within multimeric cytokine receptor complexes Proceedings of the National Academy of Sciences of the United States of America. 93: 231-235. PMID 8552611 DOI: 10.1073/Pnas.93.1.231 |
0.831 |
|
| 1995 |
Gaffen SL, Lai SY, Xu W, Gouilleux F, Groner B, Goldsmith MA, Greene WC. Signaling through the interleukin 2 receptor β chain activates a STAT-5-like DNA-binding activity Proceedings of the National Academy of Sciences of the United States of America. 92: 7192-7196. PMID 7543676 DOI: 10.1073/Pnas.92.16.7192 |
0.795 |
|
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