| Year |
Citation |
Score |
| 2013 |
Kong W, Gu P, Knudsen GA, Sipes IG. Comparison of 2,2-bis(bromomethyl)-1,3-propanediol induced genotoxicity in UROtsa cells and primary rat hepatocytes: relevance of metabolism and oxidative stress. Toxicology Letters. 222: 273-9. PMID 23954263 DOI: 10.1016/J.Toxlet.2013.07.026 |
0.768 |
|
| 2013 |
Api AM, Ritacco G, Sipes IG. Disposition and excretion of 14C-AHTN (7-acetyl-1,1,3,4,4,6-hexamethyl-1,2,3,4-tetrahydronaphthalene) and 14c-hhcb (1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethyl-cyclopenta-gamma-2-benzopyran) after intravenous administration to Sprague-Dawley rats and domestic pigs. International Journal of Toxicology. 32: 288-95. PMID 23685777 DOI: 10.1177/1091581813490202 |
0.483 |
|
| 2011 |
Kong W, Kuester RK, Gallegos A, Sipes IG. Induction of DNA damage in human urothelial cells by the brominated flame retardant 2,2-bis(bromomethyl)-1,3-propanediol: role of oxidative stress. Toxicology. 290: 271-7. PMID 22019925 DOI: 10.1016/J.Tox.2011.10.006 |
0.755 |
|
| 2011 |
Mark-Kappeler CJ, Sen N, Lukefahr A, McKee L, Sipes IG, Konhilas J, Hoyer PB. Inhibition of ovarian KIT phosphorylation by the ovotoxicant 4-vinylcyclohexene diepoxide in rats. Biology of Reproduction. 85: 755-62. PMID 21677306 DOI: 10.1095/Biolreprod.111.092742 |
0.399 |
|
| 2011 |
Cheng Y, Martinez-Guerrero LJ, Wright SH, Kuester RK, Hooth MJ, Sipes IG. Characterization of the inhibitory effects of N-butylpyridinium chloride and structurally related ionic liquids on organic cation transporters 1/2 and human toxic extrusion transporters 1/2-k in vitro and in vivo. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 39: 1755-61. PMID 21646436 DOI: 10.1124/Dmd.110.035865 |
0.766 |
|
| 2011 |
Keating AF, Fernandez SM, Mark-Kappeler CJ, Sen N, Sipes IG, Hoyer PB. Inhibition of PIK3 signaling pathway members by the ovotoxicant 4-vinylcyclohexene diepoxide in rats. Biology of Reproduction. 84: 743-51. PMID 21076081 DOI: 10.1095/Biolreprod.110.087650 |
0.335 |
|
| 2010 |
Mark-Kappeler CJ, Sen N, Keating AF, Sipes IG, Hoyer PB. Distribution and responsiveness of rat anti-Müllerian hormone during ovarian development and VCD-induced ovotoxicity. Toxicology and Applied Pharmacology. 249: 1-7. PMID 20816688 DOI: 10.1016/J.Taap.2010.08.024 |
0.403 |
|
| 2010 |
Keating AF, Sen N, Sipes IG, Hoyer PB. Dual protective role for glutathione S-transferase class pi against VCD-induced ovotoxicity in the rat ovary. Toxicology and Applied Pharmacology. 247: 71-5. PMID 20542051 DOI: 10.1016/J.Taap.2010.06.002 |
0.422 |
|
| 2010 |
Rad G, Hoehle SI, Kuester RK, Sipes IG. In vitro glucuronidation of 2,2-bis(bromomethyl)-1,3-propanediol by microsomes and hepatocytes from rats and humans. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 38: 957-62. PMID 20200232 DOI: 10.1124/Dmd.110.032110 |
0.775 |
|
| 2009 |
Knudsen GA, Cheng Y, Kuester RK, Hooth MJ, Sipes IG. Effects of dose and route on the disposition and kinetics of 1-butyl-1-methylpyrrolidinium chloride in male F-344 rats. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 37: 2171-7. PMID 19704025 DOI: 10.1124/Dmd.109.029082 |
0.801 |
|
| 2009 |
Keating AF, J Mark C, Sen N, Sipes IG, Hoyer PB. Effect of phosphatidylinositol-3 kinase inhibition on ovotoxicity caused by 4-vinylcyclohexene diepoxide and 7, 12-dimethylbenz[a]anthracene in neonatal rat ovaries. Toxicology and Applied Pharmacology. 241: 127-34. PMID 19695275 DOI: 10.1016/J.Taap.2009.08.012 |
0.353 |
|
| 2009 |
Cheng Y, Wright SH, Hooth MJ, Sipes IG. Characterization of the disposition and toxicokinetics of N-butylpyridinium chloride in male F-344 rats and female B6C3F1 mice and its transport by organic cation transporter 2. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 37: 909-16. PMID 19171679 DOI: 10.1124/Dmd.108.022681 |
0.617 |
|
| 2009 |
Hoehle SI, Knudsen GA, Sanders JM, Sipes IG. Absorption, distribution, metabolism, and excretion of 2,2-bis(bromomethyl)-1,3-propanediol in male fischer-344 rats. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 37: 408-16. PMID 19029203 DOI: 10.1124/Dmd.108.023937 |
0.786 |
|
| 2009 |
Igawa Y, Keating AF, Rajapaksa KS, Sipes IG, Hoyer PB. Evaluation of ovotoxicity induced by 7, 12-dimethylbenz[a]anthracene and its 3,4-diol metabolite utilizing a rat in vitro ovarian culture system. Toxicology and Applied Pharmacology. 234: 361-9. PMID 19027032 DOI: 10.1016/J.Taap.2008.10.009 |
0.438 |
|
| 2009 |
Goodman JE, Witorsch RJ, McConnell EE, Sipes IG, Slayton TM, Yu CJ, Franz AM, Rhomberg LR. Weight-of-evidence evaluation of reproductive and developmental effects of low doses of bisphenol A. Critical Reviews in Toxicology. 39: 1-75. PMID 18923974 DOI: 10.3109/10408440903279946 |
0.354 |
|
| 2008 |
Keating AF, Rajapaksa KS, Sipes IG, Hoyer PB. Effect of CYP2E1 gene deletion in mice on expression of microsomal epoxide hydrolase in response to VCD exposure. Toxicological Sciences : An Official Journal of the Society of Toxicology. 105: 351-9. PMID 18622027 DOI: 10.1093/Toxsci/Kfn136 |
0.381 |
|
| 2008 |
Keating AF, Sipes IG, Hoyer PB. Expression of ovarian microsomal epoxide hydrolase and glutathione S-transferase during onset of VCD-induced ovotoxicity in B6C3F(1) mice. Toxicology and Applied Pharmacology. 230: 109-16. PMID 18407309 DOI: 10.1016/J.Taap.2008.02.016 |
0.358 |
|
| 2008 |
Sipes IG, Knudsen GA, Kuester RK. The effects of dose and route on the toxicokinetics and disposition of 1-butyl-3-methylimidazolium chloride in male F-344 rats and female B6C3F1 mice. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 284-93. PMID 17967929 DOI: 10.1124/Dmd.107.018515 |
0.82 |
|
| 2008 |
Keating AF, Sen N, Sipes IG, Hoyer PB. Effect of 4-Vinylcyclohexene Diepoxide on Xenobiotic Metabolizing Enzyme Expression in the Rat Ovary. Biology of Reproduction. 78: 203-203. DOI: 10.1093/Biolreprod/78.S1.203A |
0.366 |
|
| 2007 |
Kuester RK, Sipes IG. Prediction of metabolic clearance of bisphenol A (4,4 '-dihydroxy-2,2-diphenylpropane) using cryopreserved human hepatocytes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 35: 1910-5. PMID 17646283 DOI: 10.1124/Dmd.107.014787 |
0.739 |
|
| 2007 |
Knudsen GA, Jacobs LM, Kuester RK, Sipes IG. Absorption, distribution, metabolism and excretion of intravenously and orally administered tetrabromobisphenol A [2,3-dibromopropyl ether] in male Fischer-344 rats. Toxicology. 237: 158-67. PMID 17582672 DOI: 10.1016/J.Tox.2007.05.006 |
0.816 |
|
| 2007 |
Rajapaksa KS, Cannady EA, Sipes IG, Hoyer PB. Involvement of CYP 2E1 enzyme in ovotoxicity caused by 4-vinylcyclohexene and its metabolites. Toxicology and Applied Pharmacology. 221: 215-21. PMID 17462685 DOI: 10.1016/J.Taap.2007.03.009 |
0.757 |
|
| 2007 |
Hoyer PB, Sipes IG. Development of an animal model for ovotoxicity using 4-vinylcyclohexene: a case study. Birth Defects Research. Part B, Developmental and Reproductive Toxicology. 80: 113-25. PMID 17342769 DOI: 10.1002/Bdrb.20103 |
0.353 |
|
| 2007 |
Kuester RK, Sólyom AM, Rodriguez VP, Sipes IG. The effects of dose, route, and repeated dosing on the disposition and kinetics of tetrabromobisphenol A in male F-344 rats. Toxicological Sciences : An Official Journal of the Society of Toxicology. 96: 237-45. PMID 17234645 DOI: 10.1093/Toxsci/Kfm006 |
0.793 |
|
| 2007 |
Rajapaksa KS, Sipes IG, Hoyer PB. involvement of microsomal epoxide hydrolase enzyme in ovotoxicity caused by 7,12-dimethylbenz[a]anthracene. Toxicological Sciences : An Official Journal of the Society of Toxicology. 96: 327-34. PMID 17204581 DOI: 10.1093/Toxsci/Kfl202 |
0.389 |
|
| 2006 |
Goodman JE, McConnell EE, Sipes IG, Witorsch RJ, Slayton TM, Yu CJ, Lewis AS, Rhomberg LR. An updated weight of the evidence evaluation of reproductive and developmental effects of low doses of bisphenol A. Critical Reviews in Toxicology. 36: 387-457. PMID 16954066 DOI: 10.1080/10408440600758317 |
0.427 |
|
| 2005 |
Thompson KE, Bourguet SM, Christian PJ, Benedict JC, Sipes IG, Flaws JA, Hoyer PB. Differences between rats and mice in the involvement of the aryl hydrocarbon receptor in 4-vinylcyclohexene diepoxide-induced ovarian follicle loss. Toxicology and Applied Pharmacology. 203: 114-23. PMID 15710172 DOI: 10.1016/J.Taap.2004.07.010 |
0.47 |
|
| 2004 |
Devine PJ, Sipes IG, Hoyer PB. Initiation of delayed ovotoxicity by in vitro and in vivo exposures of rat ovaries to 4-vinylcyclohexene diepoxide. Reproductive Toxicology (Elmsford, N.Y.). 19: 71-7. PMID 15336714 DOI: 10.1016/J.Reprotox.2004.06.002 |
0.438 |
|
| 2004 |
Hines RN, Adams J, Buck GM, Faber W, Holson JF, Jacobson SW, Keszler M, McMartin K, Segraves RT, Singer LT, Sipes IG, Williams PL. NTP-CERHR Expert Panel Report on the reproductive and developmental toxicity of fluoxetine. Birth Defects Research. Part B, Developmental and Reproductive Toxicology. 71: 193-280. PMID 15334524 DOI: 10.1002/Bdrb.20014 |
0.408 |
|
| 2004 |
Sweet CJ, Sólyom AM, Sipes IG. Absorption and elimination of D and C Red No. 28 in male F-344 rats. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 42: 641-8. PMID 15019189 DOI: 10.1016/j.fct.2003.11.009 |
0.339 |
|
| 2004 |
Gray GM, Cohen JT, Cunha G, Hughes C, McConnell EE, Rhomberg L, Sipes IG, Mattison D. Weight of the Evidence Evaluation of Low-Dose Reproductive and Developmental Effects of Bisphenol A Human and Ecological Risk Assessment: An International Journal. 10: 875-921. DOI: 10.1080/10807030490513883 |
0.369 |
|
| 2003 |
Cannady EA, Dyer CA, Christian PJ, Sipes IG, Hoyer PB. Expression and activity of cytochromes P450 2E1, 2A, and 2B in the mouse ovary: the effect of 4-vinylcyclohexene and its diepoxide metabolite. Toxicological Sciences : An Official Journal of the Society of Toxicology. 73: 423-30. PMID 12700394 DOI: 10.1093/Toxsci/Kfg077 |
0.769 |
|
| 2002 |
Halladay JS, Mackerer CR, Twerdok LE, Sipes IG. Comparative pharmacokinetic and disposition studies of [1-14C]1-eicosanylcyclohexane, a surrogate mineral hydrocarbon, in female Fischer-344 and Sprague-Dawley rats. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 30: 1470-7. PMID 12433821 DOI: 10.1124/Dmd.30.12.1470 |
0.737 |
|
| 2002 |
Badger DA, Smith RL, Bao J, Kuester RK, Sipes IG. Disposition and metabolism of isoeugenol in the male Fischer 344 rat. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 40: 1757-65. PMID 12419689 DOI: 10.1016/S0278-6915(02)00183-7 |
0.778 |
|
| 2002 |
Devine PJ, Sipes IG, Skinner MK, Hoyer PB. Characterization of a rat in vitro ovarian culture system to study the ovarian toxicant 4-vinylcyclohexene diepoxide. Toxicology and Applied Pharmacology. 184: 107-15. PMID 12408955 DOI: 10.1006/Taap.2002.9502 |
0.405 |
|
| 2002 |
Mayer LP, Pearsall NA, Christian PJ, Devine PJ, Payne CM, McCuskey MK, Marion SL, Sipes IG, Hoyer PB. Long-term effects of ovarian follicular depletion in rats by 4-vinylcyclohexene diepoxide. Reproductive Toxicology (Elmsford, N.Y.). 16: 775-81. PMID 12401505 DOI: 10.1016/S0890-6238(02)00048-5 |
0.391 |
|
| 2002 |
Pritchett JJ, Kuester RK, Sipes IG. Metabolism of bisphenol a in primary cultured hepatocytes from mice, rats, and humans. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 30: 1180-5. PMID 12386122 DOI: 10.1124/dmd.30.11.1180 |
0.777 |
|
| 2002 |
Hu X, Flaws JA, Sipes IG, Hoyer PB. Activation of mitogen-activated protein kinases and AP-1 transcription factor in ovotoxicity induced by 4-vinylcyclohexene diepoxide in rats. Biology of Reproduction. 67: 718-24. PMID 12193377 DOI: 10.1095/Biolreprod.102.004259 |
0.411 |
|
| 2002 |
Cannady EA, Dyer CA, Christian PJ, Sipes IG, Hoyer PB. Expression and activity of microsomal epoxide hydrolase in follicles isolated from mouse ovaries. Toxicological Sciences : An Official Journal of the Society of Toxicology. 68: 24-31. PMID 12075107 DOI: 10.1093/Toxsci/68.1.24 |
0.764 |
|
| 2002 |
Thompson KE, Sipes IG, Greenstein BD, Hoyer PB. 17beta-estradiol affords protection against 4-vinylcyclohexene diepoxide-induced ovarian follicle loss in Fischer-344 rats. Endocrinology. 143: 1058-65. PMID 11861533 DOI: 10.1210/Endo.143.3.8665 |
0.359 |
|
| 2002 |
Kuester RK, Waalkes MP, Goering PL, Fisher BL, McCuskey RS, Sipes IG. Differential hepatotoxicity induced by cadmium in Fischer 344 and Sprague-Dawley rats. Toxicological Sciences : An Official Journal of the Society of Toxicology. 65: 151-9. PMID 11752694 DOI: 10.1093/Toxsci/65.1.151 |
0.771 |
|
| 2001 |
Hoyer PB, Cannady EA, Kroeger NA, Sipes IG. Mechanisms of ovotoxicity induced by environmental chemicals: 4-vinylcyclohexene diepoxide as a model chemical. Advances in Experimental Medicine and Biology. 500: 73-81. PMID 11765019 DOI: 10.1007/978-1-4615-0667-6_8 |
0.705 |
|
| 2001 |
Hu X, Christian P, Sipes IG, Hoyer PB. Expression and redistribution of cellular Bad, Bax, and Bcl-X(L) protein is associated with VCD-induced ovotoxicity in rats. Biology of Reproduction. 65: 1489-95. PMID 11673266 DOI: 10.1095/Biolreprod65.5.1489 |
0.415 |
|
| 2001 |
Fontaine SM, Hoyer PB, Halpert JR, Sipes IG. Role of induction of specific hepatic cytochrome P450 isoforms in epoxidation of 4-vinylcyclohexene. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 29: 1236-42. PMID 11502734 |
0.808 |
|
| 2001 |
Fontaine SM, Hoyer PB, Sipes IG. Evaluation of hepatic cytochrome P4502E1 in the species-dependent bioactivation of 4-vinylcyclohexene. Life Sciences. 69: 923-34. PMID 11488405 DOI: 10.1016/S0024-3205(01)01170-5 |
0.797 |
|
| 2001 |
Devine PJ, Sipes IG, Hoyer PB. Effect of 4-vinylcyclohexene diepoxide dosing in rats on GSH levels in liver and ovaries. Toxicological Sciences : An Official Journal of the Society of Toxicology. 62: 315-20. PMID 11452144 DOI: 10.1093/Toxsci/62.2.315 |
0.472 |
|
| 2001 |
Hu X, Christian PJ, Thompson KE, Sipes IG, Hoyer PB. Apoptosis induced in rats by 4-vinylcyclohexene diepoxide is associated with activation of the caspase cascades. Biology of Reproduction. 65: 87-93. PMID 11420227 DOI: 10.1095/Biolreprod65.1.87 |
0.421 |
|
| 2001 |
Hoyer PB, Devine PJ, Hu X, Thompson KE, Sipes IG. Ovarian toxicity of 4-vinylcyclohexene diepoxide: a mechanistic model. Toxicologic Pathology. 29: 91-9. PMID 11215690 DOI: 10.1080/019262301301418892 |
0.399 |
|
| 2001 |
Fontaine SM, Mash EA, Hoyer PB, Sipes IG. Stereochemical aspects of vinylcyclohexene bioactivation in rodent hepatic microsomes and purified human cytochrome P450 enzyme systems. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 29: 179-84. PMID 11159809 |
0.786 |
|
| 2000 |
Burkey JL, Sauer JM, McQueen CA, Sipes IG. Cytotoxicity and genotoxicity of methyleugenol and related congeners-- a mechanism of activation for methyleugenol. Mutation Research. 453: 25-33. PMID 11006409 DOI: 10.1016/S0027-5107(00)00070-1 |
0.436 |
|
| 2000 |
Borman SM, Christian PJ, Sipes IG, Hoyer PB. Ovotoxicity in female Fischer rats and B6 mice induced by low-dose exposure to three polycyclic aromatic hydrocarbons: comparison through calculation of an ovotoxic index. Toxicology and Applied Pharmacology. 167: 191-8. PMID 10986010 DOI: 10.1006/Taap.2000.9006 |
0.347 |
|
| 2000 |
Younis HS, Hoglen NC, Kuester RK, Gunawardhana L, Sipes IG. 1,2-Dichlorobenzene-mediated hepatocellular oxidative stress in Fischer-344 and Sprague-Dawley rats. Toxicology and Applied Pharmacology. 163: 141-8. PMID 10698672 DOI: 10.1006/Taap.1999.8860 |
0.8 |
|
| 1999 |
Halladay JS, Sauer JM, Sipes IG. Metabolism and disposition of [(14)C]1-nitronaphthalene in male Sprague-Dawley rats. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 27: 1456-65. PMID 10570027 |
0.731 |
|
| 1999 |
Kao SW, Sipes IG, Hoyer PB. Early effects of ovotoxicity induced by 4-vinylcyclohexene diepoxide in rats and mice. Reproductive Toxicology (Elmsford, N.Y.). 13: 67-75. PMID 10080302 DOI: 10.1016/S0890-6238(98)00061-6 |
0.465 |
|
| 1999 |
Doerr-Stevens JK, Liu J, Stevens GJ, Kraner JC, Fontaine SM, Halpert JR, Sipes IG. Induction of cytochrome P-450 enzymes after repeated exposure to 4-vinylcyclohexene in B6C3F1 mice. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 27: 281-7. PMID 9929517 |
0.796 |
|
| 1998 |
Hoglen NC, Younis HS, Hartley DP, Gunawardhana L, Lantz RC, Sipes IG. 1,2-Dichlorobenzene-induced lipid peroxidation in male Fischer 344 rats is Kupffer cell dependent. Toxicological Sciences : An Official Journal of the Society of Toxicology. 46: 376-85. PMID 10048141 DOI: 10.1006/Toxs.1998.2523 |
0.752 |
|
| 1998 |
Hoglen NC, Regan SP, Hensel JL, Younis HS, Sauer JM, Steup DR, Miller MJ, Waterman SJ, Twerdok LE, Sipes IG. Alteration of Kupffer cell function and morphology by low melt point paraffin wax in female Fischer-344 but not Sprague-Dawley rats. Toxicological Sciences : An Official Journal of the Society of Toxicology. 46: 176-84. PMID 9928681 DOI: 10.1006/toxs.1998.2509 |
0.721 |
|
| 1998 |
Badger D, Kraner J, Fraser D, Hoglen N, Halpert J, Sipes IG. Reduction of thyroid hormone may participate in the modulation of cytochromes P450 2C11 and 3A2 by retinol. Life Sciences. 63: PL367-72. PMID 9870717 DOI: 10.1016/S0024-3205(98)00516-5 |
0.429 |
|
| 1998 |
Bao J, Sauer JM, Smith RL, Kuester RK, Kattnig MJ, Sipes IG. Sulfhydryl-dependent biotransformation and macromolecular binding of 1,2-dibromo-2,4-dicyanobutane in blood. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 26: 1001-7. PMID 9763406 |
0.726 |
|
| 1998 |
Sauer JM, Smith RL, Bao J, Kattnig MJ, Kuester RK, Sipes IG. Metabolic and dispositional fate of 1,2-dibromo-2,4-dicyanobutane in the male fischer 344 Rat. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 26: 429-36. PMID 9571224 |
0.775 |
|
| 1997 |
Sauer JM, Bao J, Smith RL, Kuester RK, Mayersohn M, Sipes IG. Absorption, disposition, and metabolism of trans-methyl styryl ketone in female B6C3F1 mice. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 25: 1184-90. PMID 9321522 |
0.765 |
|
| 1997 |
Bao J, Smith RL, Sauer JM, Pillai U, Sipes IG. Simultaneous determination of cyclohexene oxide and its metabolites in rat plasma and urine by gas chromatography. Journal of Chromatography. B, Biomedical Sciences and Applications. 696: 59-68. PMID 9300909 DOI: 10.1016/S0378-4347(97)00232-6 |
0.316 |
|
| 1997 |
Sauer JM, Waalkes MP, Hooser SB, Kuester RK, McQueen CA, Sipes IG. Suppression of Kupffer cell function prevents cadmium induced hepatocellular necrosis in the male Sprague-Dawley rat. Toxicology. 121: 155-64. PMID 9230447 DOI: 10.1016/S0300-483X(97)00062-0 |
0.778 |
|
| 1997 |
Badger DA, Kuester RK, Sauer JM, Sipes IG. Gadolinium chloride reduces cytochrome P450: relevance to chemical-induced hepatotoxicity. Toxicology. 121: 143-53. PMID 9230446 DOI: 10.1016/S0300-483X(97)00065-6 |
0.765 |
|
| 1997 |
Sauer JM, Smith RL, Bao J, Kattnig MJ, Kuester RK, McClure TD, Mayersohn M, Sipes IG. Oral and topical absorption, disposition kinetics, and the metabolic fate of trans-methyl styryl ketone in the male Fischer 344 rat. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 25: 732-9. PMID 9193875 |
0.769 |
|
| 1997 |
Sauer JM, Bao J, Smith RL, McClure TD, Mayersohn M, Pillai U, Cunningham ML, Sipes IG. Absorption, disposition kinetics, and metabolic pathways of cyclohexene oxide in the male Fischer 344 rat and female B6C3F1 mouse. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 25: 371-8. PMID 9172957 |
0.395 |
|
| 1997 |
Sauer JM, Waalkes MP, Hooser SB, Baines AT, Kuester RK, Sipes IG. Tolerance induced by all-trans-retinol to the hepatotoxic effects of cadmium in rats: role of metallothionein expression. Toxicology and Applied Pharmacology. 143: 110-9. PMID 9073599 DOI: 10.1006/taap.1996.8050 |
0.783 |
|
| 1996 |
Badger DA, Sauer JM, Hoglen NC, Jolley CS, Sipes IG. The role of inflammatory cells and cytochrome P450 in the potentiation of CCl4-induced liver injury by a single dose of retinol. Toxicology and Applied Pharmacology. 141: 507-19. PMID 8975775 DOI: 10.1006/taap.1996.0316 |
0.382 |
|
| 1996 |
Wueweera JB, Gandolfi AJ, Badger DA, Sipes IG, Brendel K. Vitamin A potentiation of vinylidene chloride hepatotoxicity in rats and precision-cut rat liver slices. Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology. 34: 73-83. PMID 8937894 DOI: 10.1093/Toxsci/34.1.73 |
0.477 |
|
| 1996 |
Springer LN, Flaws JA, Sipes IG, Hoyer PB. Follicular mechanisms associated with 4-vinylcyclohexene diepoxide-induced ovotoxicity in rats. Reproductive Toxicology (Elmsford, N.Y.). 10: 137-43. PMID 8919611 DOI: 10.1016/0890-6238(95)02056-X |
0.435 |
|
| 1996 |
Doerr JK, Hollis EA, Sipes IG. Species difference in the ovarian toxicity of 1,3-butadiene epoxides in B6C3F1 mice and Sprague-Dawley rats. Toxicology. 113: 128-36. PMID 8901892 DOI: 10.1016/0300-483X(96)03437-3 |
0.419 |
|
| 1996 |
Ziegler TL, Pillai UA, Smith RL, Kattnig MJ, Liebler DC, Mayersohn M, Sipes IG. Absorption and disposition kinetics of 3,3',4,4'-tetrachloroazoxybenzene in the male Fischer 344 rat. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 24: 1009-14. PMID 8886612 |
0.338 |
|
| 1996 |
Springer LN, Tilly JL, Sipes IG, Hoyer PB. Enhanced expression of bax in small preantral follicles during 4-vinylcyclohexene diepoxide-induced ovotoxicity in the rat. Toxicology and Applied Pharmacology. 139: 402-10. PMID 8806858 DOI: 10.1006/Taap.1996.0181 |
0.303 |
|
| 1996 |
Pillai UA, Ziegler TL, Wang DX, Kattnig MJ, McClure T, Liebler DC, Mayersohn M, Sipes IG. 3,3',4,4'-tetrachloroazobenzene absorption, disposition, and metabolism in male Fischer 344 rats. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 24: 238-44. PMID 8742237 |
0.345 |
|
| 1996 |
Sauer JM, Sipes IG. Modulation of chemical-induced lung and liver toxicity by all-trans-retinol in the male Sprague-Dawley rat. Toxicology. 105: 237-49. PMID 8571361 DOI: 10.1016/0300-483X(95)03219-6 |
0.421 |
|
| 1995 |
Hooser SB, Rosengren RJ, Hill DA, Mobley SA, Sipes IG. Vitamin A modulation of xenobiotic-induced hepatotoxicity in rodents. Environmental Health Perspectives. 39-43. PMID 7698082 DOI: 10.1289/ehp.94102s939 |
0.379 |
|
| 1995 |
Sauer JM, Hooser SB, Badger DA, Baines A, Sipes IG. Alterations in chemically induced tissue injury related to all-trans-retinol pretreatment in rodents. Drug Metabolism Reviews. 27: 299-323. PMID 7641581 DOI: 10.3109/03602539509029828 |
0.384 |
|
| 1995 |
Fisher RL, Hasal SJ, Sipes IG, Gandolfi AJ, Brendel K. Comparative metabolism and toxicity of dichlorobenzenes in Sprague-Dawley, Fischer-344 and human liver slices. Human & Experimental Toxicology. 14: 414-21. PMID 7612303 DOI: 10.1177/096032719501400505 |
0.441 |
|
| 1995 |
Sauer JM, Hooser SB, Sipes IG. All-trans-retinol alteration of 1-nitronaphthalene-induced pulmonary and hepatic injury by modulation of associated inflammatory responses in the male Sprague-Dawley rat. Toxicology and Applied Pharmacology. 133: 139-49. PMID 7597703 DOI: 10.1006/taap.1995.1135 |
0.329 |
|
| 1995 |
Hooser SB, DeMerell DG, Douds DA, Hoyer P, Sipes IG. Testicular germ cell toxicity caused by vinylcyclohexene diepoxide in mice. Reproductive Toxicology (Elmsford, N.Y.). 9: 359-67. PMID 7496092 DOI: 10.1016/0890-6238(95)00022-3 |
0.37 |
|
| 1995 |
ROSENGREN RJ, SAUER J, HOOSER SB, SIPES IG. The Interactions between Retinol and Five Different Hepatotoxicants in the Swiss Webster Mouse Toxicological Sciences. 25: 281-292. DOI: 10.1006/Faat.1995.1064 |
0.384 |
|
| 1994 |
Flaws JA, Salyers KL, Sipes IG, Hoyer PB. Reduced ability of rat preantral ovarian follicles to metabolize 4-vinyl-1-cyclohexene diepoxide in vitro. Toxicology and Applied Pharmacology. 126: 286-94. PMID 8209381 DOI: 10.1006/Taap.1994.1118 |
0.31 |
|
| 1994 |
Salyers KL, Barr J, Sipes IG. In vitro metabolism of theophylline by rat and human liver tissue. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 24: 389-99. PMID 8079498 DOI: 10.3109/00498259409043242 |
0.357 |
|
| 1994 |
Flaws JA, Doerr JK, Sipes IG, Hoyer PB. Destruction of preantral follicles in adult rats by 4-vinyl-1-cyclohexene diepoxide. Reproductive Toxicology (Elmsford, N.Y.). 8: 509-14. PMID 7881202 DOI: 10.1016/0890-6238(94)90033-7 |
0.377 |
|
| 1993 |
elSisi AE, Hall P, Sim WL, Earnest DL, Sipes IG. Characterization of vitamin A potentiation of carbon tetrachloride-induced liver injury. Toxicology and Applied Pharmacology. 119: 280-8. PMID 8480337 DOI: 10.1006/taap.1993.1070 |
0.342 |
|
| 1993 |
Winter SM, Sipes IG. The disposition of acrylic acid in the male Sprague-Dawley rat following oral or topical administration. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 31: 615-21. PMID 8406237 DOI: 10.1016/0278-6915(93)90043-X |
0.332 |
|
| 1993 |
Gunawardhana L, Mobley SA, Sipes IG. Modulation of 1,2-dichlorobenzene hepatotoxicity in the Fischer-344 rat by a scavenger of superoxide anions and an inhibitor of Kupffer cells. Toxicology and Applied Pharmacology. 119: 205-13. PMID 8386865 DOI: 10.1006/taap.1993.1061 |
0.326 |
|
| 1993 |
Fisher RL, Gandolfi AJ, Sipes IG, Brendel K. Culture medium composition affects the relative toxicities of chlorobenzenes in rat liver slices and the isolated perfused liver. Drug and Chemical Toxicology. 16: 321-39. PMID 8281887 DOI: 10.3109/01480549308998224 |
0.406 |
|
| 1993 |
Steup DR, Hall P, McMillan DA, Sipes IG. Time course of hepatic injury and recovery following coadministration of carbon tetrachloride and trichloroethylene in Fischer-344 rats. Toxicologic Pathology. 21: 327-34. PMID 8248722 DOI: 10.1177/019262339302100309 |
0.453 |
|
| 1993 |
Dart RC, Liebler DC, Sipes IG. Hepatic injury and lipid peroxidation during hemorrhagic shock and resuscitation. Life Sciences. 53: 1685-90. PMID 8231649 DOI: 10.1016/0024-3205(93)90205-H |
0.315 |
|
| 1993 |
Zheng W, Winter SM, Mayersohn M, Bishop JB, Sipes IG. Toxicokinetics of sulfasalazine (salicylazosulfapyridine) and its metabolites in B6C3F1 mice. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 21: 1091-7. PMID 7905389 |
0.31 |
|
| 1992 |
Smith BJ, Plowchalk DR, Sipes IG, Mattison DR. Comparison of random and serial sections in assessment of ovarian toxicity. Reproductive Toxicology (Elmsford, N.Y.). 5: 379-83. PMID 1806143 DOI: 10.1016/0890-6238(91)90097-Y |
0.311 |
|
| 1992 |
Fisher R, Barr J, Zukoski CF, Putnam CW, Sipes IG, Gandolfi AJ, Brendel K. In-vitro hepatotoxicity of three dichlorobenzene isomers in human liver slices. Human & Experimental Toxicology. 10: 357-63. PMID 1683550 DOI: 10.1177/096032719101000510 |
0.397 |
|
| 1992 |
Weber GL, Sipes IG. In vitro metabolism and bioactivation of 1,2,3-trichloropropane. Toxicology and Applied Pharmacology. 113: 152-8. PMID 1553750 DOI: 10.1016/0041-008X(92)90020-S |
0.452 |
|
| 1991 |
Fisher R, Putnam CW, Koep LJ, Sipes IG, Gandolfi AJ, Brendel K. Cryopreservation of pig and human liver slices. Cryobiology. 28: 131-42. PMID 2070615 DOI: 10.1016/0011-2240(91)90015-G |
0.354 |
|
| 1991 |
Sipes IG, el Sisi AE, Sim WW, Mobley SA, Earnest DL. Reactive oxygen species in the progression of CCl4-induced liver injury. Advances in Experimental Medicine and Biology. 283: 489-97. PMID 2069020 DOI: 10.1007/978-1-4684-5877-0_65 |
0.33 |
|
| 1991 |
Smith BJ, Mattison DR, Sipes IG. Hepatic bioactivation of 4-vinylcyclohexene to ovotoxic epoxides. Advances in Experimental Medicine and Biology. 283: 465-70. PMID 2069018 DOI: 10.1007/978-1-4684-5877-0_62 |
0.365 |
|
| 1991 |
Smith BJ, Sipes IG. Epoxidation of 4-vinylcyclohexene by human hepatic microsomes. Toxicology and Applied Pharmacology. 109: 367-71. PMID 2068732 DOI: 10.1016/0041-008X(91)90182-E |
0.368 |
|
| 1991 |
Steup DR, Wiersma D, McMillan DA, Sipes IG. Pretreatment with drinking water solutions containing trichloroethylene or chloroform enhances the hepatotoxicity of carbon tetrachloride in Fischer 344 rats. Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology. 16: 798-809. PMID 1884917 DOI: 10.1016/0272-0590(91)90165-Z |
0.475 |
|
| 1991 |
Stine ER, Gunawardhana L, Sipes IG. The acute hepatotoxicity of the isomers of dichlorobenzene in Fischer-344 and Sprague-Dawley rats: isomer-specific and strain-specific differential toxicity. Toxicology and Applied Pharmacology. 109: 472-81. PMID 1853346 DOI: 10.1016/0041-008X(91)90010-C |
0.325 |
|
| 1990 |
Smith BJ, Mattison DR, Sipes IG. The role of epoxidation in 4-vinylcyclohexene-induced ovarian toxicity. Toxicology and Applied Pharmacology. 105: 372-81. PMID 2237912 DOI: 10.1016/0041-008X(90)90141-G |
0.453 |
|
| 1990 |
Smith BJ, Carter DE, Sipes IG. Comparison of the disposition and in vitro metabolism of 4-vinylcyclohexene in the female mouse and rat Toxicology and Applied Pharmacology. 105: 364-371. PMID 2237911 DOI: 10.1016/0041-008X(90)90140-P |
0.52 |
|
| 1990 |
Smith BJ, Sipes IG, Stevens JC, Halpert JR. The biochemical basis for the species difference in hepatic microsomal 4-vinylcyclohexene epoxidation between female mice and rats. Carcinogenesis. 11: 1951-7. PMID 2225327 DOI: 10.1093/Carcin/11.11.1951 |
0.435 |
|
| 1990 |
Weber GL, Sipes IG. Covalent interactions of 1,2,3-trichloropropane with hepatic macromolecules: studies in the male F-344 rat. Toxicology and Applied Pharmacology. 104: 395-402. PMID 1696752 DOI: 10.1016/0041-008X(90)90161-M |
0.38 |
|
| 1989 |
Duignan DB, Sipes IG, Ciaccio PJ, Halpert JR. The metabolism of xenobiotics and endogenous compounds by the constitutive dog liver cytochrome P450 PBD-2. Archives of Biochemistry and Biophysics. 267: 294-304. PMID 3143308 DOI: 10.1016/0003-9861(88)90035-5 |
0.312 |
|
| 1989 |
Elsisi AE, Carter DE, Sipes IG. Dermal absorption of phthalate diesters in rats. Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology. 12: 70-7. PMID 2925020 DOI: 10.1016/0272-0590(89)90063-8 |
0.347 |
|
| 1989 |
Mufti SI, Becker G, Sipes IG. Effect of chronic dietary ethanol consumption on the initiation and promotion of chemically-induced esophageal carcinogenesis in experimental rats. Carcinogenesis. 10: 303-9. PMID 2912582 DOI: 10.1093/Carcin/10.2.303 |
0.334 |
|
| 1988 |
Russell DH, Buckley AR, Shah GN, Sipes IG, Blask DE, Benson B. Hypothalamic site of action of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Toxicology and Applied Pharmacology. 94: 496-502. PMID 3400098 DOI: 10.1016/0041-008X(88)90290-6 |
0.313 |
|
| 1988 |
Mufti SI, Sipes IG. Differential induction of DNA strand breaks by nitrosamines in the rat liver and esophagus. Cancer Letters. 40: 203-11. PMID 3383179 DOI: 10.1016/0304-3835(88)90012-2 |
0.37 |
|
| 1988 |
Mufti SI, Prabhala R, Moriguchi S, Sipes IG, Watson RR. Functional and numerical alterations induced by ethanol in the cellular immune system. Immunopharmacology. 15: 85-93. PMID 3372229 DOI: 10.1016/0162-3109(88)90055-0 |
0.306 |
|
| 1987 |
Jones MK, Weisenburger WP, Sipes IG, Russell DH. Circadian alterations in prolactin, corticosterone, and thyroid hormone levels and down-regulation of prolactin receptor activity by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicology and Applied Pharmacology. 87: 337-50. PMID 3824389 DOI: 10.1016/0041-008X(87)90295-X |
0.396 |
|
| 1987 |
Szebeni J, Eskelson CD, Mufti SI, Watson RR, Sipes IG. Inhibition of ethanol induced ethane exhalation by carcinogenic pretreatment of rats 12 months earlier. Life Sciences. 39: 2587-91. PMID 3796206 DOI: 10.1016/0024-3205(86)90113-X |
0.323 |
|
| 1987 |
Duignan DB, Sipes IG, Leonard TB, Halpert JR. Purification and characterization of the dog hepatic cytochrome P-450 isozyme responsible for the metabolism of 2,2',4,4',5,5'-hexachlorobiphenyl. Archives of Biochemistry and Biophysics. 255: 290-303. PMID 3109323 DOI: 10.1016/0003-9861(87)90396-1 |
0.441 |
|
| 1987 |
Petry TW, Sipes IG. Modulation of monocrotaline-induced hepatic genotoxicity in rats. Carcinogenesis. 8: 415-9. PMID 3102099 DOI: 10.1093/Carcin/8.3.415 |
0.369 |
|
| 1987 |
Petry TW, Bowden GT, Buhler DR, Sipes IG. ErratumGenotoxicity of the pyrrolizidine alkaloid jacobine in rats Toxicology Letters. 36. DOI: 10.1016/0378-4274(87)90047-6 |
0.377 |
|
| 1986 |
Eigenberg DA, Bozigian HP, Carter DE, Sipes IG. Distribution, excretion, and metabolism of butylbenzyl phthalate in the rat Journal of Toxicology and Environmental Health. 17: 445-456. PMID 3959124 DOI: 10.1080/15287398609530839 |
0.359 |
|
| 1986 |
Eigenberg DA, Carter DE, Schram KH, Sipes IG. Examination of the differential hepatotoxicity of diallyl phthalate in rats and mice Toxicology and Applied Pharmacology. 86: 12-21. PMID 3764931 DOI: 10.1016/0041-008X(86)90395-9 |
0.467 |
|
| 1986 |
Macdonald JR, Gandolfi AJ, Sipes IG. Amelioration of carbon tetrachloride-induced hepatic necrosis by post-toxicant treatment with cystamine Toxicology. 39: 135-148. PMID 3705080 DOI: 10.1016/0300-483X(86)90131-9 |
0.422 |
|
| 1986 |
Sipes IG, Wiersma DA, Armstrong DJ. The role of glutathione in the toxicity of xenobiotic compounds: metabolic activation of 1,2-dibromoethane by glutathione. Advances in Experimental Medicine and Biology. 197: 457-67. PMID 3532707 DOI: 10.1007/978-1-4684-5134-4_44 |
0.367 |
|
| 1986 |
Wiersma DA, Schnellmann RG, Sipes IG. The in vitro metabolism and bioactivation of 1,2-dibromoethane (ethylene dibromide) by human liver. Journal of Biochemical Toxicology. 1: 1-11. PMID 3271877 DOI: 10.1002/Jbt.2570010302 |
0.622 |
|
| 1986 |
Vickers AE, Sipes IG, Brendel K. Metabolism-related spectral characterization and subcellular distribution of polychlorinated biphenyl congeners in isolated rat hepatocytes. Biochemical Pharmacology. 35: 297-306. PMID 3080006 DOI: 10.1016/0006-2952(86)90529-0 |
0.385 |
|
| 1985 |
Macdonald JR, Gandolfi AJ, Sipes IG. Hepatic cysteamine and non-protein sulfhydryl levels following cystamine or cysteamine treatment of galactosamine-poisoned rats Drug and Chemical Toxicology. 8: 483-494. PMID 4092620 DOI: 10.3109/01480548509041071 |
0.323 |
|
| 1985 |
Connors S, Meyer FJ, Sundheimer DW, Sipes IG, Brendel K. An all-glass apparatus for liver perfusion of lipophilic substrates. I. Construction and physical characteristics. Journal of Pharmacological Methods. 13: 83-94. PMID 3974257 DOI: 10.1016/0160-5402(85)90070-1 |
0.329 |
|
| 1985 |
Potter CL, Sipes IG, Russell DH. Effects of two hexachlorobiphenyl isomers on ornithine decarboxylase induction: Inhibitory effects correlate with aryl hydrocarbon hydroxylase activity Life Sciences. 37: 2557-2561. PMID 3935896 DOI: 10.1016/0024-3205(85)90614-9 |
0.307 |
|
| 1985 |
Miller MJ, Sipes IG, Perry DF, Carter DE. Pharmacokinetics of o-nitroanisole in Fischer 344 rats Drug Metabolism and Disposition. 13: 527-531. PMID 2865097 |
0.338 |
|
| 1985 |
Lind RC, Gandolfi AJ, Sipes IG, Brown BR. Comparison of the Requirements for Hepatic Injury with Halothane and Enflurane in Rats Anesthesia & Analgesia. 64: 955???963. DOI: 10.1213/00000539-198510000-00003 |
0.376 |
|
| 1984 |
MacDonald JR, Gandolfi AJ, Sipes IG. Cystamine modulation of galactosamine-induced hepatotoxicity Toxicology and Applied Pharmacology. 73: 551-558. PMID 6719469 DOI: 10.1016/0041-008X(84)90107-8 |
0.426 |
|
| 1984 |
Schnellmann RG, Wiersma DA, Randall DJ, Smith TL, Sipes IG. Hepatic mixed function oxygenase activity and glutathione S-transferase activity in mice following ethanol consumption and withdrawal. Toxicology. 32: 105-16. PMID 6540493 DOI: 10.1016/0300-483X(84)90130-6 |
0.485 |
|
| 1984 |
Lind RC, Gandolfi AJ, Sipes IG, Brown BR. The involvement of endotoxin in halothane-associated liver injury. Anesthesiology. 61: 544-50. PMID 6496992 DOI: 10.1097/00000542-198411000-00012 |
0.356 |
|
| 1984 |
Schnellmann RG, Volp RF, Putnam CW, Sipes IG. The hydroxylation, dechlorination, and glucuronidation of 4,4'-dichlorobiphenyl (4-DCB) by human hepatic microsomes. Biochemical Pharmacology. 33: 3503-9. PMID 6437410 DOI: 10.1016/0006-2952(84)90127-8 |
0.596 |
|
| 1984 |
Volp RF, Sipes IG, Falcoz C, Carter DE, Gross JF. Disposition of 1,2,3-trichloropropane in the fischer 344 rat: Conventional and physiological pharmacokinetics Toxicology and Applied Pharmacology. 75: 8-17. PMID 6431641 DOI: 10.1016/0041-008X(84)90070-X |
0.342 |
|
| 1984 |
Macfarland RT, Gandolfi AJ, Sipes IG. Extra-hepatic gsh-dependent metabolism of 1,2-dibromoethane (dbe) and 1,2-dibromo-3-chloropropane (dbcp) IN the rat and mouse Drug and Chemical Toxicology. 7: 213-227. PMID 6376058 DOI: 10.3109/01480548409035104 |
0.332 |
|
| 1984 |
White RD, Petry TW, Sipes IG. The bioactivation of 1,2-dibromoethane in rat hepatocytes: deuterium isotope effect. Chemico-Biological Interactions. 49: 225-33. PMID 6373030 DOI: 10.1016/0009-2797(84)90063-2 |
0.385 |
|
| 1984 |
Kaminsky LS, Dunbar DA, Wang PP, Beaune P, Larrey D, Guengerich FP, Schnellmann RG, Sipes IG. Human hepatic cytochrome P-450 composition as probed by in vitro microsomal metabolism of warfarin. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 12: 470-7. PMID 6148215 |
0.545 |
|
| 1983 |
Miller MS, Brendel K, Burks TF, Sipes IG. Interaction of capsaicinoids with drug-metabolizing systems. Relationship to toxicity. Biochemical Pharmacology. 32: 547-51. PMID 6847703 DOI: 10.1016/0006-2952(83)90537-3 |
0.372 |
|
| 1983 |
Schnellmann RG, Putnam CW, Sipes IG. Metabolism of 2,2',3,3',6,6'-hexachlorobiphenyl and 2,2',4,4',5,5'-hexachlorobiphenyl by human hepatic microsomes. Biochemical Pharmacology. 32: 3233-9. PMID 6416258 DOI: 10.1016/0006-2952(83)90209-5 |
0.595 |
|
| 1983 |
Miller MS, Miller MJ, Burks TF, Sipes IG. Altered retrograde axonal transport of nerve growth factor after single and repeated doses of acrylamide in the rat. Toxicology and Applied Pharmacology. 69: 96-101. PMID 6190267 DOI: 10.1016/0041-008X(83)90124-2 |
0.345 |
|
| 1983 |
Potter CL, Sipes IG, Russell DH. Hypothyroxinemia and hypothermia in rats in response to 2,3,7,8-tetrachlorodibenzo-p-dioxin administration Toxicology and Applied Pharmacology. 69: 89-95. PMID 6134353 DOI: 10.1016/0041-008X(83)90123-0 |
0.378 |
|
| 1982 |
MacDonald JR, Gandolfi AJ, Sipes IG. Acetone potentiation of 1,1,2-trichloroethane hepatotoxicity Toxicology Letters. 13: 57-69. PMID 7179309 DOI: 10.1016/0378-4274(82)90139-4 |
0.302 |
|
| 1982 |
Macdonald JR, Gandolfi AJ, Sipes IG. Covalent binding of 14c-1,1,2-trichloroethane to hepatic proteins following acetone pretreatment Drug and Chemical Toxicology. 5: 233-247. PMID 7151718 DOI: 10.3109/01480548209041055 |
0.319 |
|
| 1982 |
Evans TL, Chang SY, Alberts DS, Sipes IG, Brendel K. In vitro degradation of L-phenylalanine mustard (L-PAM). Cancer Chemotherapy and Pharmacology. 8: 175-8. PMID 7105381 DOI: 10.1007/Bf00255479 |
0.316 |
|
| 1982 |
Miller MJ, Carter DE, Sipes IG. Pharmacokinetics of acrylamide in Fisher-334 rats Toxicology and Applied Pharmacology. 63: 36-44. PMID 7071872 DOI: 10.1016/0041-008X(82)90024-2 |
0.373 |
|
| 1982 |
Sipes IG, Slocumb ML, Chen HSG, Carter DE. 2,3,6,2′,3′,6′-Hexachlorobiphenyl: Distribution, metabolism, and excretion in the dog and the monkey Toxicology and Applied Pharmacology. 62: 317-324. PMID 6800067 DOI: 10.1016/0041-008X(82)90130-2 |
0.304 |
|
| 1982 |
Lind RC, Gandolfi AJ, Sipes IG, Brown BR. ROLE OF ENDOTOXIN IN THE HALOTHANE HEPATITIS MODEL IN RATS Anesthesiology. 57: A220. DOI: 10.1097/00000542-198209001-00220 |
0.382 |
|
| 1981 |
Sipes IG, Gandolfi AJ. Role of reactive intermediates in halothane associated liver injury Advances in Experimental Medicine and Biology. 136: 603-618. PMID 7344482 DOI: 10.1007/978-1-4757-0674-1_44 |
0.313 |
|
| 1981 |
Maiorino RM, Sipes IG, Gandolfi AJ, Brown BR, Lind RC. Factors affecting the formation of chlorotrifluoroethane and chlorodifluoroethylene from halothane. Anesthesiology. 54: 383-9. PMID 7224207 DOI: 10.1097/00000542-198105000-00007 |
0.305 |
|
| 1981 |
Gandolfi AJ, Sipes IG, Brown BR. Detection of covalently bound halothane metabolites in the hypoxic rat model for halothane hepatotoxicity Toxicological Sciences. 1: 255-259. DOI: 10.1016/S0272-0590(81)80124-8 |
0.373 |
|
| 1980 |
Sipes IG, Gandolfi AJ, Pohl LR, Krishna G, Brown BR. Comparison of the biotransformation and hepatotoxicity of halothane and deuterated halothane. The Journal of Pharmacology and Experimental Therapeutics. 214: 716-20. PMID 7400974 |
0.314 |
|
| 1980 |
Haag SM, Sipes IG. Differential effects of acetone or Aroclor 1254 pretreatment on the microsomal activation of dimethylnitrosamine to a mutagen Mutation Research. 74: 431-438. PMID 6780907 DOI: 10.1016/0165-1161(80)90174-0 |
0.4 |
|
| 1980 |
Jee RC, Sipes IG, Gandolfi AJ, Brown BR. Factors influencing halothane hepatotoxicity in the rat hypoxic model. Toxicology and Applied Pharmacology. 52: 267-77. PMID 6767300 DOI: 10.1016/0041-008X(80)90114-3 |
0.451 |
|
| 1979 |
McLain GE, Sipes IG, Brown BR. An animal model of halothane hepatotoxicity: roles of enzyme induction and hypoxia. Anesthesiology. 51: 321-6. PMID 484893 DOI: 10.1097/00000542-197910000-00008 |
0.476 |
|
| 1979 |
Brown BR, Sipes IG, Jee R, Gandolfi AJ. Characterization of hypoxic model for halothane hepatotoxicity Anesthesiology. 51. |
0.331 |
|
| 1978 |
Sipes IG, Slocumb ML, Holtzman G. Stimulation of microsomal dimethylnitrosamine-N-demethylase by pretreatment of mice with acetone. Chemico-Biological Interactions. 21: 155-66. PMID 679394 DOI: 10.1016/0009-2797(78)90016-9 |
0.347 |
|
| 1978 |
Manen CA, Costa M, Sipes IG, Russell DH. Further evidence of cyclic AMP-mediated hypertrophy as a prerequisite of drug-specific enzyme induction. Biochemical Pharmacology. 27: 219-24. PMID 203290 DOI: 10.1016/0006-2952(78)90304-0 |
0.426 |
|
| 1978 |
Vaughan RW, Sipes IG, Brown BR. Role of biotransformation in the toxicity of inhalation anesthetics. Life Sciences. 23: 2447-62. PMID 32456 DOI: 10.1016/0024-3205(78)90168-6 |
0.317 |
|
| 1978 |
Halladay SC, Carter DE, Sipes IG. A relationship between the metabolism of bumetanide and its diuretic activity in the rat Drug Metabolism and Disposition. 6: 45-49. PMID 23273 |
0.366 |
|
| 1977 |
Sipes IG, Brown BR. An animal model of hepatotoxicity associated with halothane anesthesia. Anesthesiology. 45: 622-8. PMID 984478 DOI: 10.1097/00000542-197612000-00005 |
0.323 |
|
| 1977 |
Brown BR, Sipes IG. Biotransformation and hepatotoxicity of halothane Biochemical Pharmacology. 26: 2091-2094. PMID 337973 DOI: 10.1016/0006-2952(77)90256-8 |
0.379 |
|
| 1977 |
Sipes IG, Krishna G, Gillette JR. Bioactivation of carbon tetrachloride, chloroform and bromotrichloromethane: role of cytochrome P-450. Life Sciences. 20: 1541-8. PMID 17803 DOI: 10.1016/0024-3205(77)90446-5 |
0.569 |
|
| 1976 |
Byus CV, Costa M, Sipes IG, Brodie BB, Russell DH. Activation of 3':5'-cyclic AMP-dependent protein kinase and induction of ornithine decarboxylase as early events in induction of mixed-function oxygenases. Proceedings of the National Academy of Sciences of the United States of America. 73: 1241-5. PMID 177981 DOI: 10.1073/Pnas.73.4.1241 |
0.479 |
|
| 1975 |
Brown BR, Sipes IG, Sagalyn AM. Mechanisms of acute hepatic toxicity: chloroform, halothane, and glutathione. Anesthesiology. 41: 554-61. PMID 4433055 DOI: 10.1097/00000542-197412000-00005 |
0.309 |
|
| 1975 |
Halladay SC, Carter DE, Sipes IG, Brodie BB, Bressler R. Evidence for the metabolism of bumetanide in man. Life Sciences. 17: 1003-9. PMID 1195984 DOI: 10.1016/0024-3205(75)90455-5 |
0.565 |
|
| 1975 |
Chvapil M, Sipes IG, Ludwig JC, Halladay SC. Inhibition of NADPH oxidation and oxidative metabolism of drugs in liver microsomes by zinc Biochemical Pharmacology. 24: 917-919. PMID 235935 DOI: 10.1016/0006-2952(75)90164-1 |
0.307 |
|
| 1974 |
Maling HM, Eichelbaum FM, Saul W, Sipes IG, Brown EA, Gillette JR. Nature of the protection against carbon tetrachloride-induced hepatotoxicity produced by pretreatment with dibenamine (N-(2-chloroethyl)dibenzylamine). Biochemical Pharmacology. 23: 1479-91. PMID 4847532 DOI: 10.1016/0006-2952(74)90385-2 |
0.622 |
|
| 1974 |
Stripp B, Sipes IG, Maling HM, Gillette JR. Dibenamine impairment of rat hepatic microsomal enzymes and its relation to hepatotoxicity induced by CCl4 and dimethylnitrosamine Drug Metabolism and Disposition. 2: 464-468. PMID 4156310 |
0.345 |
|
| 1973 |
Sipes IG, Stripp B, Krishna G, Maling HM, Gillette JR. Enhanced hepatic microsomal activity by pretreatment of rats with acetone or isopropanol. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 142: 237-40. PMID 4405141 DOI: 10.3181/00379727-142-36996 |
0.611 |
|
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