Year |
Citation |
Score |
2024 |
Kim DM, Liu J, Whitmore MA, Tobin I, Zhao Z, Zhang G. Two intestinal microbiota-derived metabolites, deoxycholic acid and butyrate, synergize to enhance host defense peptide synthesis and alleviate necrotic enteritis. Journal of Animal Science and Biotechnology. 15: 29. PMID 38429856 DOI: 10.1186/s40104-024-00995-9 |
0.377 |
|
2023 |
Tobin I, Zhang G. Regulation of Host Defense Peptide Synthesis by Polyphenols. Antibiotics (Basel, Switzerland). 12. PMID 37107022 DOI: 10.3390/antibiotics12040660 |
0.43 |
|
2023 |
Lyu W, Deng Z, Zhang G. High-Throughput Screening for Epigenetic Compounds That Induce Human β-Defensin 1 Synthesis. Antibiotics (Basel, Switzerland). 12. PMID 36830097 DOI: 10.3390/antibiotics12020186 |
0.381 |
|
2022 |
Lyu W, Mi D, Vinson PN, Xiao Y, Zhang G. Large-Scale Identification of Multiple Classes of Host Defense Peptide-Inducing Compounds for Antimicrobial Therapy. International Journal of Molecular Sciences. 23. PMID 35955551 DOI: 10.3390/ijms23158400 |
0.409 |
|
2022 |
Deng Z, Lyu W, Zhang G. High-Throughput Identification of Epigenetic Compounds to Enhance Chicken Host Defense Peptide Gene Expression. Antibiotics (Basel, Switzerland). 11. PMID 35884187 DOI: 10.3390/antibiotics11070933 |
0.418 |
|
2022 |
Yang Q, Burkardt AC, Sunkara LT, Xiao K, Zhang G. Natural Cyclooxygenase-2 Inhibitors Synergize With Butyrate to Augment Chicken Host Defense Peptide Gene Expression. Frontiers in Immunology. 13: 819222. PMID 35273602 DOI: 10.3389/fimmu.2022.819222 |
0.446 |
|
2021 |
Yang Q, Fong LA, Lyu W, Sunkara LT, Xiao K, Zhang G. Synergistic Induction of Chicken Antimicrobial Host Defense Peptide Gene Expression by Butyrate and Sugars. Frontiers in Microbiology. 12: 781649. PMID 34956146 DOI: 10.3389/fmicb.2021.781649 |
0.775 |
|
2021 |
Robinson K, Yang Q, Li H, Zhang L, Aylward B, Arsenault RJ, Zhang G. Butyrate and Forskolin Augment Host Defense, Barrier Function, and Disease Resistance Without Eliciting Inflammation. Frontiers in Nutrition. 8: 778424. PMID 34778349 DOI: 10.3389/fnut.2021.778424 |
0.479 |
|
2021 |
Yang Q, Whitmore MA, Robinson K, Lyu W, Zhang G. Butyrate, Forskolin, and Lactose Synergistically Enhance Disease Resistance by Inducing the Expression of the Genes Involved in Innate Host Defense and Barrier Function. Antibiotics (Basel, Switzerland). 10. PMID 34680756 DOI: 10.3390/antibiotics10101175 |
0.446 |
|
2021 |
Wang J, Lyu W, Zhang W, Chen Y, Luo F, Wang Y, Ji H, Zhang G. Discovery of natural products capable of inducing porcine host defense peptide gene expression using cell-based high throughput screening. Journal of Animal Science and Biotechnology. 12: 14. PMID 33431034 DOI: 10.1186/s40104-020-00536-0 |
0.398 |
|
2020 |
Robinson K, Xiao Y, Johnson TJ, Chen B, Yang Q, Lyu W, Wang J, Fansler N, Becker S, Liu J, Yang H, Zhang G. Chicken Intestinal Mycobiome: Initial Characterization and Its Response to Bacitracin Methylene Disalicylate. Applied and Environmental Microbiology. PMID 32358003 DOI: 10.1128/Aem.00304-20 |
0.365 |
|
2020 |
Xu X, Hua H, Wang L, He P, Zhang L, Qin Q, Yu C, Wang X, Zhang G, Liu Y. Holly polyphenols alleviate intestinal inflammation and alter microbiota composition in lipopolysaccharide-challenged pigs. The British Journal of Nutrition. 1-31. PMID 31928547 DOI: 10.1017/S0007114520000082 |
0.375 |
|
2019 |
Liu H, Zeng X, Zhang G, Hou C, Li N, Yu H, Shang L, Zhang X, Trevisi P, Yang F, Liu Z, Qiao S. Maternal milk and fecal microbes guide the spatiotemporal development of mucosa-associated microbiota and barrier function in the porcine neonatal gut. Bmc Biology. 17: 106. PMID 31852478 DOI: 10.1186/S12915-019-0729-2 |
0.305 |
|
2019 |
Robinson K, Becker S, Xiao Y, Lyu W, Yang Q, Zhu H, Yang H, Zhao J, Zhang G. Differential Impact of Subtherapeutic Antibiotics and Ionophores on Intestinal Microbiota of Broilers. Microorganisms. 7. PMID 31443457 DOI: 10.3390/microorganisms7090282 |
0.3 |
|
2019 |
Wang G, Huang S, Wang Y, Cai S, Yu H, Liu H, Zeng X, Zhang G, Qiao S. Bridging intestinal immunity and gut microbiota by metabolites. Cellular and Molecular Life Sciences : Cmls. PMID 31250035 DOI: 10.1007/S00018-019-03190-6 |
0.402 |
|
2019 |
Wang X, Wang W, Wang L, Yu C, Zhang G, Zhu H, Wang C, Zhao S, Hu CA, Liu Y. Lentinan modulates intestinal microbiota and enhances barrier integrity in a piglet model challenged with lipopolysaccharide. Food & Function. PMID 30638239 DOI: 10.1039/C8Fo02438C |
0.431 |
|
2018 |
Yang H, Xiang Y, Robinson K, Wang J, Zhang G, Zhao J, Xiao Y. Gut Microbiota Is a Major Contributor to Adiposity in Pigs. Frontiers in Microbiology. 9: 3045. PMID 30619136 DOI: 10.3389/Fmicb.2018.03045 |
0.362 |
|
2018 |
Deng Z, Wang J, Lyu W, Wieneke X, Matts R, Ma X, Zhang G. Development of a Cell-Based High-Throughput Screening Assay to Identify Porcine Host Defense Peptide-Inducing Compounds. Journal of Immunology Research. 2018: 5492941. PMID 30581875 DOI: 10.1155/2018/5492941 |
0.437 |
|
2018 |
Zhang L, Wang X, Chen S, Wang S, Tu Z, Zhang G, Zhu H, Li X, Xiong J, Liu Y. Medium-Chain Triglycerides Attenuate Liver Injury in Lipopolysaccharide-Challenged Pigs by Inhibiting Necroptotic and Inflammatory Signaling Pathways. International Journal of Molecular Sciences. 19. PMID 30469452 DOI: 10.3390/Ijms19113697 |
0.327 |
|
2018 |
Robinson K, Ma X, Liu Y, Qiao S, Hou Y, Zhang G. Dietary modulation of endogenous host defense peptide synthesis as an alternative approach to in-feed antibiotics. Animal Nutrition (Zhongguo Xu Mu Shou Yi Xue Hui). 4: 160-169. PMID 30140755 DOI: 10.1016/J.Aninu.2018.01.003 |
0.473 |
|
2018 |
Lyu W, Deng Z, Sunkara LT, Becker S, Robinson K, Matts R, Zhang G. High Throughput Screening for Natural Host Defense Peptide-Inducing Compounds as Novel Alternatives to Antibiotics. Frontiers in Cellular and Infection Microbiology. 8: 191. PMID 29942796 DOI: 10.3389/Fcimb.2018.00191 |
0.783 |
|
2018 |
Zhang J, Chen X, Liu P, Zhao J, Sun J, Guan W, J Johnston L, L Levesque C, Fan P, He T, Zhang G, Ma X. Dietary Clostridium Butyricum induces a phased shift in fecal microbiota structure and increases the acetic acid-producing bacteria in a weaned piglet model. Journal of Agricultural and Food Chemistry. PMID 29683328 DOI: 10.1021/Acs.Jafc.8B01253 |
0.311 |
|
2018 |
Xiao Y, Kong F, Xiang Y, Zhou W, Wang J, Yang H, Zhang G, Zhao J. Comparative biogeography of the gut microbiome between Jinhua and Landrace pigs. Scientific Reports. 8: 5985. PMID 29654314 DOI: 10.1038/S41598-018-24289-Z |
0.383 |
|
2018 |
Nie C, He T, Zhang W, Zhang G, Ma X. Branched Chain Amino Acids: Beyond Nutrition Metabolism. International Journal of Molecular Sciences. 19. PMID 29570613 DOI: 10.3390/Ijms19040954 |
0.35 |
|
2018 |
Liu H, Wang J, He T, Becker S, Zhang G, Li D, Ma X. Butyrate: A Double-Edged Sword for Health? Advances in Nutrition (Bethesda, Md.). 9: 21-29. PMID 29438462 DOI: 10.1093/Advances/Nmx009 |
0.335 |
|
2018 |
Ma N, Guo P, Zhang J, He T, Kim SW, Zhang G, Ma X. Nutrients Mediate Intestinal Bacteria-Mucosal Immune Crosstalk. Frontiers in Immunology. 9: 5. PMID 29416535 DOI: 10.3389/Fimmu.2018.00005 |
0.405 |
|
2017 |
Liu H, Hou C, Wang G, Jia H, Yu H, Zeng X, Thacker PA, Zhang G, Qiao S. Lactobacillus reuteri I5007 Modulates Intestinal Host Defense Peptide Expression in the Model of IPEC-J2 Cells and Neonatal Piglets. Nutrients. 9. PMID 28561758 DOI: 10.3390/Nu9060559 |
0.481 |
|
2016 |
Fan P, Song P, Li L, Huang C, Chen J, Yang W, Qiao S, Wu G, Zhang G, Ma X. Modulation of Biogenic Amines on Intestinal Signaling Proteins and Its Detection. Current Protein & Peptide Science. PMID 27356940 DOI: 10.2174/1389203717666160627073048 |
0.346 |
|
2016 |
Wang J, Han M, Zhang G, Qiao S, Li D, Ma X. The Signal Pathway of Antibiotic Alternatives on Intestinal Microbiota and Immune Function. Current Protein & Peptide Science. PMID 27226197 DOI: 10.2174/1389203717666160526123351 |
0.424 |
|
2016 |
Zhang L, Lu L, Li S, Zhang G, Ouyang L, Robinson K, Tang Y, Zhu Q, Li D, Hu Y, Liu Y. 1,25-Dihydroxyvitamin-D3 Induces Avian β-Defensin Gene Expression in Chickens. Plos One. 11: e0154546. PMID 27135828 DOI: 10.1371/Journal.Pone.0154546 |
0.437 |
|
2015 |
Robinson K, Deng Z, Hou Y, Zhang G. Regulation of the Intestinal Barrier Function by Host Defense Peptides. Frontiers in Veterinary Science. 2: 57. PMID 26664984 DOI: 10.3389/Fvets.2015.00057 |
0.441 |
|
2015 |
Lyu W, Curtis AR, Sunkara LT, Zhang G. Transcriptional Regulation of Antimicrobial Host Defense Peptides. Current Protein & Peptide Science. PMID 26122785 DOI: 10.2174/1389203716666150630133432 |
0.787 |
|
2014 |
Zhang G, Sunkara LT. Avian antimicrobial host defense peptides: from biology to therapeutic applications. Pharmaceuticals (Basel, Switzerland). 7: 220-47. PMID 24583933 DOI: 10.3390/Ph7030220 |
0.773 |
|
2014 |
Bommineni YR, Pham GH, Sunkara LT, Achanta M, Zhang G. Immune regulatory activities of fowlicidin-1, a cathelicidin host defense peptide. Molecular Immunology. 59: 55-63. PMID 24491488 DOI: 10.1016/J.Molimm.2014.01.004 |
0.78 |
|
2014 |
Liu H, Zhang J, Zhang S, Yang F, Thacker PA, Zhang G, Qiao S, Ma X. Oral administration of Lactobacillus fermentum I5007 favors intestinal development and alters the intestinal microbiota in formula-fed piglets. Journal of Agricultural and Food Chemistry. 62: 860-6. PMID 24404892 DOI: 10.1021/Jf403288R |
0.316 |
|
2014 |
Sunkara LT, Zeng X, Curtis AR, Zhang G. Cyclic AMP synergizes with butyrate in promoting β-defensin 9 expression in chickens. Molecular Immunology. 57: 171-80. PMID 24141182 DOI: 10.1016/J.Molimm.2013.09.003 |
0.771 |
|
2013 |
Jiang W, Sunkara LT, Zeng X, Deng Z, Myers SM, Zhang G. Differential regulation of human cathelicidin LL-37 by free fatty acids and their analogs. Peptides. 50: 129-38. PMID 24140860 DOI: 10.1016/J.Peptides.2013.10.008 |
0.757 |
|
2013 |
Zeng X, Sunkara LT, Jiang W, Bible M, Carter S, Ma X, Qiao S, Zhang G. Induction of porcine host defense peptide gene expression by short-chain fatty acids and their analogs. Plos One. 8: e72922. PMID 24023657 DOI: 10.1371/Journal.Pone.0072922 |
0.799 |
|
2013 |
Patil AA, Ouellette AJ, Lu W, Zhang G. Rattusin, an intestinal α-defensin-related peptide in rats with a unique cysteine spacing pattern and salt-insensitive antibacterial activities. Antimicrobial Agents and Chemotherapy. 57: 1823-31. PMID 23380721 DOI: 10.1128/Aac.02237-12 |
0.657 |
|
2012 |
Sunkara LT, Jiang W, Zhang G. Modulation of antimicrobial host defense peptide gene expression by free fatty acids. Plos One. 7: e49558. PMID 23166711 DOI: 10.1371/Journal.Pone.0049558 |
0.785 |
|
2012 |
Achanta M, Sunkara LT, Dai G, Bommineni YR, Jiang W, Zhang G. Tissue expression and developmental regulation of chicken cathelicidin antimicrobial peptides. Journal of Animal Science and Biotechnology. 3: 15. PMID 22958518 DOI: 10.1186/2049-1891-3-15 |
0.754 |
|
2011 |
Sunkara LT, Achanta M, Schreiber NB, Bommineni YR, Dai G, Jiang W, Lamont S, Lillehoj HS, Beker A, Teeter RG, Zhang G. Butyrate enhances disease resistance of chickens by inducing antimicrobial host defense peptide gene expression. Plos One. 6: e27225. PMID 22073293 DOI: 10.1371/Journal.Pone.0027225 |
0.802 |
|
2011 |
Oguiura N, Boni-Mitake M, Affonso R, Zhang G. In vitro antibacterial and hemolytic activities of crotamine, a small basic myotoxin from rattlesnake Crotalus durissus. The Journal of Antibiotics. 64: 327-31. PMID 21386851 DOI: 10.1038/Ja.2011.10 |
0.398 |
|
2011 |
Takahashi D, Shukla SK, Prakash O, Zhang G. Erratum: Structural determinants of host defense peptides for antimicrobial activity and target cell selectivity (Biochimie. (2010) 92 (1236-1241)) Biochimie. 93. DOI: 10.1016/J.Biochi.2010.12.007 |
0.42 |
|
2010 |
Bommineni YR, Achanta M, Alexander J, Sunkara LT, Ritchey JW, Zhang G. A fowlicidin-1 analog protects mice from lethal infections induced by methicillin-resistant Staphylococcus aureus. Peptides. 31: 1225-30. PMID 20381563 DOI: 10.1016/J.Peptides.2010.03.037 |
0.761 |
|
2010 |
Takahashi D, Shukla SK, Prakash O, Zhang G. Structural determinants of host defense peptides for antimicrobial activity and target cell selectivity. Biochimie. 92: 1236-41. PMID 20188791 DOI: 10.1016/J.Biochi.2010.02.023 |
0.432 |
|
2009 |
Xiao Y, Herrera AI, Bommineni YR, Soulages JL, Prakash O, Zhang G. The central kink region of fowlicidin-2, an alpha-helical host defense peptide, is critically involved in bacterial killing and endotoxin neutralization. Journal of Innate Immunity. 1: 268-80. PMID 20375584 DOI: 10.1159/000174822 |
0.406 |
|
2007 |
Sang Y, Teresa Ortega M, Rune K, Xiau W, Zhang G, Soulages JL, Lushington GH, Fang J, Williams TD, Blecha F, Melgarejo T. Canine cathelicidin (K9CATH): gene cloning, expression, and biochemical activity of a novel pro-myeloid antimicrobial peptide. Developmental and Comparative Immunology. 31: 1278-96. PMID 17462733 DOI: 10.1016/J.Dci.2007.03.007 |
0.525 |
|
2007 |
Bommineni YR, Dai H, Gong YX, Soulages JL, Fernando SC, Desilva U, Prakash O, Zhang G. Fowlicidin-3 is an alpha-helical cationic host defense peptide with potent antibacterial and lipopolysaccharide-neutralizing activities. The Febs Journal. 274: 418-28. PMID 17229147 DOI: 10.1111/J.1742-4658.2006.05589.X |
0.516 |
|
2006 |
Xiao Y, Dai H, Bommineni YR, Soulages JL, Gong YX, Prakash O, Zhang G. Structure-activity relationships of fowlicidin-1, a cathelicidin antimicrobial peptide in chicken. The Febs Journal. 273: 2581-93. PMID 16817888 DOI: 10.1111/J.1742-4658.2006.05261.X |
0.431 |
|
2006 |
Aono S, Li C, Zhang G, Kemppainen RJ, Gard J, Lu W, Hu X, Schwartz DD, Morrison EE, Dykstra C, Shi J. Molecular and functional characterization of bovine beta-defensin-1. Veterinary Immunology and Immunopathology. 113: 181-90. PMID 16777238 DOI: 10.1016/J.Vetimm.2006.05.002 |
0.422 |
|
2006 |
Hasenstein JR, Zhang G, Lamont SJ. Analyses of Five gallinacin genes and the Salmonella enterica serovar Enteritidis response in poultry. Infection and Immunity. 74: 3375-80. PMID 16714567 DOI: 10.1128/Iai.00027-06 |
0.346 |
|
2006 |
Sang Y, Patil AA, Zhang G, Ross CR, Blecha F. Bioinformatic and expression analysis of novel porcine beta-defensins. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 17: 332-9. PMID 16596454 DOI: 10.1007/S00335-005-0158-0 |
0.555 |
|
2006 |
Xiao Y, Cai Y, Bommineni YR, Fernando SC, Prakash O, Gilliland SE, Zhang G. Identification and functional characterization of three chicken cathelicidins with potent antimicrobial activity. The Journal of Biological Chemistry. 281: 2858-67. PMID 16326712 DOI: 10.1074/Jbc.M507180200 |
0.449 |
|
2005 |
Patil AA, Cai Y, Sang Y, Blecha F, Zhang G. Cross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract. Physiological Genomics. 23: 5-17. PMID 16033865 DOI: 10.1152/Physiolgenomics.00104.2005 |
0.569 |
|
2005 |
Davis EG, Sang Y, Rush B, Zhang G, Blecha F. Molecular cloning and characterization of equine NK-lysin. Veterinary Immunology and Immunopathology. 105: 163-9. PMID 15797485 DOI: 10.1016/J.Vetimm.2004.12.007 |
0.33 |
|
2004 |
Patil A, Hughes AL, Zhang G. Rapid evolution and diversification of mammalian alpha-defensins as revealed by comparative analysis of rodent and primate genes. Physiological Genomics. 20: 1-11. PMID 15494476 DOI: 10.1152/Physiolgenomics.00150.2004 |
0.56 |
|
2004 |
Xiao Y, Hughes AL, Ando J, Matsuda Y, Cheng JF, Skinner-Noble D, Zhang G. A genome-wide screen identifies a single beta-defensin gene cluster in the chicken: implications for the origin and evolution of mammalian defensins. Bmc Genomics. 5: 56. PMID 15310403 DOI: 10.1186/1471-2164-5-56 |
0.404 |
|
2004 |
Zhang D, Zhang G, Hayden MS, Greenblatt MB, Bussey C, Flavell RA, Ghosh S. A toll-like receptor that prevents infection by uropathogenic bacteria. Science (New York, N.Y.). 303: 1522-6. PMID 15001781 DOI: 10.1126/Science.1094351 |
0.413 |
|
2003 |
Krehbiel CR, Rust SR, Zhang G, Gilliland SE. Bacterial direct-fed microbials in ruminant diets: Performance response and mode of action Journal of Animal Science. 81. DOI: 10.2527/2003.8114_Suppl_2E120X |
0.342 |
|
2002 |
Zhang G, Ghosh S. Negative regulation of toll-like receptor-mediated signaling by Tollip. The Journal of Biological Chemistry. 277: 7059-65. PMID 11751856 DOI: 10.1074/Jbc.M109537200 |
0.361 |
|
2001 |
Zhang G, Ghosh S. Molecular mechanisms of NF-kappaB activation induced by bacterial lipopolysaccharide through Toll-like receptors. Journal of Endotoxin Research. 6: 453-7. PMID 11521070 DOI: 10.1179/096805100101532414 |
0.361 |
|
2001 |
Zhang G, Ghosh S. Toll-like receptor-mediated NF-kappaB activation: a phylogenetically conserved paradigm in innate immunity. The Journal of Clinical Investigation. 107: 13-9. PMID 11134172 DOI: 10.1172/Jci11837 |
0.442 |
|
2000 |
Wu H, Zhang G, Minton JE, Ross CR, Blecha F. Regulation of cathelicidin gene expression: induction by lipopolysaccharide, interleukin-6, retinoic acid, and Salmonella enterica serovar typhimurium infection. Infection and Immunity. 68: 5552-8. PMID 10992453 DOI: 10.1128/Iai.68.10.5552-5558.2000 |
0.474 |
|
2000 |
Zhang G, Ross CR, Blecha F. Porcine antimicrobial peptides: New prospects for ancient molecules of host defense Veterinary Research. 31: 277-296. PMID 10863946 DOI: 10.1051/Vetres:2000121 |
0.491 |
|
2000 |
Zhang G, Wu H, Ross CR, Minton JE, Blecha F. Cloning of porcine NRAMP1 and its induction by lipopolysaccharide, tumor necrosis factor alpha, and interleukin-1beta: role of CD14 and mitogen-activated protein kinases. Infection and Immunity. 68: 1086-93. PMID 10678911 DOI: 10.1128/Iai.68.3.1086-1093.2000 |
0.437 |
|
1999 |
Zhang G, Hiraiwa H, Yasue H, Wu H, Ross CR, Troyer D, Blecha F. Cloning and characterization of the gene for a new epithelial β- defensin. Genomic structure, chromosomal localization, and evidence for its constitutive expression Journal of Biological Chemistry. 274: 24031-24037. PMID 10446172 DOI: 10.1074/Jbc.274.34.24031 |
0.448 |
|
1999 |
Shi J, Zhang G, Wu H, Ross C, Blecha F, Ganz T. Porcine epithelial β-defensin 1 is expressed in the dorsal tongue at antimicrobial concentrations Infection and Immunity. 67: 3121-3127. PMID 10338529 DOI: 10.1128/Iai.67.6.3121-3127.1999 |
0.412 |
|
1999 |
Wu H, Zhang G, Ross CR, Blecha F. Cathelicidin gene expression in porcine tissues: Roles in ontogeny and tissue specificity Infection and Immunity. 67: 439-442. PMID 9864252 DOI: 10.1128/Iai.67.1.439-442.1999 |
0.428 |
|
1998 |
Zhang G, Wu H, Shi J, Ganz T, Ross CR, Blecha F. Molecular cloning and tissue expression of porcine β-defensin-1 Febs Letters. 424: 37-40. PMID 9537511 DOI: 10.1016/S0014-5793(98)00134-3 |
0.446 |
|
1997 |
Zhang G, Ross CR, Dritz SS, Nietfeld JC, Blecha F. Salmonella infection increases porcine antibacterial peptide concentrations in serum Clinical and Diagnostic Laboratory Immunology. 4: 774-777. PMID 9384306 DOI: 10.1128/Cdli.4.6.774-777.1997 |
0.374 |
|
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