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Jennifer R. Molina, Ph.D. - Publications

Affiliations: 
2009 The University of Texas Graduate School of Biomedical Sciences at Houston 
Area:
Molecular Biology, Biochemistry
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27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Gozgit JM, Vasbinder MM, Abo RP, Kunii K, Kuplast-Barr KG, Gui B, Lu AZ, Molina JR, Minissale E, Swinger KK, Wigle TJ, Blackwell DJ, Majer CR, Ren Y, Niepel M, et al. PARP7 negatively regulates the type I interferon response in cancer cells and its inhibition triggers antitumor immunity. Cancer Cell. PMID 34375612 DOI: 10.1016/j.ccell.2021.06.018  0.333
2020 Schenkel L, Molina J, Swinger K, Abo R, Blackwell D, Cheung A, Church W, Kuplast-Barr K, Lu A, Minissale E, Niepel M, Vasbinder M, Wigle T, Richon V, Keilhack H, et al. Abstract 1038: A potent and selective PARP14 inhibitor decreases pro-tumor macrophage function and elicits inflammatory responses in tumor explants Cancer Research. 80: 1038-1038. DOI: 10.1158/1538-7445.Am2020-1038  0.373
2018 Molina JR, Sun Y, Protopopova M, Gera S, Bandi M, Bristow C, McAfoos T, Morlacchi P, Ackroyd J, Agip AA, Al-Atrash G, Asara J, Bardenhagen J, Carrillo CC, Carroll C, et al. An inhibitor of oxidative phosphorylation exploits cancer vulnerability. Nature Medicine. PMID 29892070 DOI: 10.1038/S41591-018-0052-4  0.412
2018 Marszalek JR, Seth S, Corti D, Zhang Q, Echeverria GV, Han L, Sun Y, Molina J, Gera S, Chang E, Khor TO, Mahendra M, Feng N, McAfoos T, Giuliani V, et al. Abstract 2856: Targeting OXPHOS with IACS-010759 to eliminate standard of care resistant tumor cells Cancer Research. 78: 2856-2856. DOI: 10.1158/1538-7445.Am2018-2856  0.447
2018 Francesco MED, Marszalek JR, McAfoos T, Carroll CL, Kang Z, Liu G, Theroff JP, Bardenhager JP, Bandi ML, Molina JR, Gera S, Protopopova M, Sun Y, Do MKG, Feng N, et al. Abstract 1655: Discovery and development of IACS-010759, a novel inhibitor of Complex I currently in phase I studies to exploit oxidative phosphorylation dependency in acute myeloid leukemia and solid tumors Cancer Research. 78: 1655-1655. DOI: 10.1158/1538-7445.Am2018-1655  0.394
2017 Baran N, Han L, Sweeney SR, Lodi A, Herbrich S, Cavazos A, Ma H, Feng N, Chen H, Kaminski M, Dunner K, Tang G, Alatrash G, Molina J, Guzman ML, et al. Inhibition of Oxphos with Iacs-010759 Depletes AML Leukemia Initiating Cells (LIC) in Vitro and Improves Survival in Pre-Clinical AML Models Blood. 130: 1350-1350. DOI: 10.1182/Blood.V130.Suppl_1.1350.1350  0.316
2017 Molina J, Bandi M, Bardenhagen J, Bristow C, Carroll C, Chang E, Cross J, Daver N, Feng N, Do MG, Greer J, Han J, Hirst J, Huang S, Jiang Y, et al. Abstract 4971: IACS-010759, a novel inhibitor of complex I in Phase I clinical development to target OXPHOS dependent tumors Cancer Research. 77: 4971-4971. DOI: 10.1158/1538-7445.Am2017-4971  0.454
2017 Baran N, Han L, Herbrich S, Sweeney SR, Lodi A, Gay J, Feng N, Molina JR, Kaminski M, Guzman ML, Al-Atrash G, Tiziani S, Marszalek JR, Konopleva M. Novel Complex I inhibitor IACS-010759 Targets Leukemia Initiating Cells (LICs) in AML Patients Clinical Lymphoma Myeloma and Leukemia. 17: S297. DOI: 10.1016/J.Clml.2017.07.089  0.32
2016 Jinesh GG, Molina JR, Huang L, Laing NM, Mills GB, Bar-Eli M, Kamat AM. Mitochondrial oligomers boost glycolysis in cancer stem cells to facilitate blebbishield-mediated transformation after apoptosis. Cell Death Discovery. 2: 16003. PMID 27551498 DOI: 10.1038/Cddiscovery.2016.3  0.342
2016 Molina JR, Protopopova M, Bandi M, Bardenhagen J, Bristow C, Carroll C, Chang E, Feng N, Do MG, Greer J, Huang S, Jiang Y, Konopleva M, Matre P, Han J, et al. Abstract 335: Title: IACS-010759 is a novel clinical candidate that targets AML cells by inducing a metabolic catastrophe through inhibition of oxidative phosphorylation Cancer Research. 76: 335-335. DOI: 10.1158/1538-7445.Am2016-335  0.451
2015 Mitra S, Molina J, Mills GB, Dennison JB. Characterization of the role Rab25 in energy metabolism and cancer using extracellular flux analysis and material balance. Methods in Molecular Biology (Clifton, N.J.). 1298: 195-205. PMID 25800844 DOI: 10.1007/978-1-4939-2569-8_17  0.301
2015 Konopleva MY, Zal T, Millward NMZ, Cho B, Harutyunyan K, Zal A, Mu H, Konoplev S, Benito J, Velez J, Bueso-Ramso C, Molina J, Bhattacharya PK, Francesco MED, Marszalek J, et al. Abstract PL07-01: Altered metabolism in leukemic microenvironment Molecular Cancer Therapeutics. 14. DOI: 10.1158/1535-7163.Targ-15-Pl07-01  0.417
2015 Molina JR, Protopopova M, Bandi M, Bardenhagen J, Bristow C, Alimova M, Carroll C, Chang E, Feng N, Do MG, Greer J, Huang S, Jiang Y, Konopleva M, Matre P, et al. Abstract LB-A15: IACS-010759 is a novel inhibitor of oxidative phosphorylation that selectively targets AML cells by inducing a metabolic catastrophe Molecular Cancer Therapeutics. 14. DOI: 10.1158/1535-7163.Targ-15-Lb-A15  0.408
2014 Molina J, Morlacchi P, Silva L, Dennison J, Mills G. Extracellular lactate cooperates with limited glucose and glutamine to sustain breast cancer cell survival by providing ATP, NADPH, amino acids, and glutathione Cancer and Metabolism. 2: 49. DOI: 10.1186/2049-3002-2-S1-P49  0.382
2012 Hill SM, Lu Y, Molina J, Heiser LM, Spellman PT, Speed TP, Gray JW, Mills GB, Mukherjee S. Bayesian inference of signaling network topology in a cancer cell line. Bioinformatics (Oxford, England). 28: 2804-10. PMID 22923301 DOI: 10.1093/Bioinformatics/Bts514  0.32
2012 Molina JR, Agarwal NK, Morales FC, Hayashi Y, Aldape KD, Cote G, Georgescu MM. PTEN, NHERF1 and PHLPP form a tumor suppressor network that is disabled in glioblastoma. Oncogene. 31: 1264-74. PMID 21804599 DOI: 10.1038/Onc.2011.324  0.583
2011 Dennison JB, Molina JR, Guo H, Mills GB. Abstract 1273: Metabolic networks and the role of LDHB in breast cancer Cancer Research. 71: 1273-1273. DOI: 10.1158/1538-7445.Am2011-1273  0.399
2011 Molina J, Dennison J, Zhang F, Mills G. P4-05-03: Mechanism Underlying Metabolic Heterogeneity in Breast Cancer Subtypes. Cancer Research. 71. DOI: 10.1158/0008-5472.Sabcs11-P4-05-03  0.424
2010 Hayashi Y, Molina JR, Hamilton SR, Georgescu MM. NHERF1/EBP50 is a new marker in colorectal cancer. Neoplasia (New York, N.Y.). 12: 1013-22. PMID 21170265 DOI: 10.1593/Neo.10780  0.554
2010 Molina JR, Morales FC, Hayashi Y, Aldape KD, Georgescu MM. Loss of PTEN binding adapter protein NHERF1 from plasma membrane in glioblastoma contributes to PTEN inactivation. Cancer Research. 70: 6697-703. PMID 20736378 DOI: 10.1158/0008-5472.Can-10-1271  0.565
2010 Cortez MA, Nicoloso MS, Shimizu M, Rossi S, Gopisetty G, Molina JR, Carlotti C, Tirapelli D, Neder L, Brassesco MS, Scrideli CA, Tone LG, Georgescu MM, Zhang W, Puduvalli V, et al. miR-29b and miR-125a regulate podoplanin and suppress invasion in glioblastoma. Genes, Chromosomes & Cancer. 49: 981-90. PMID 20665731 DOI: 10.1002/Gcc.20808  0.496
2010 Molina JR, Hayashi Y, Stephens C, Georgescu MM. Invasive glioblastoma cells acquire stemness and increased Akt activation. Neoplasia (New York, N.Y.). 12: 453-63. PMID 20563248 DOI: 10.1593/Neo.10126  0.588
2010 Zhang J, Zhao D, Park HK, Wang H, Dyer RB, Liu W, Klee GG, McNiven MA, Tindall DJ, Molina JR, Fei P. FAVL elevation in human tumors disrupts Fanconi anemia pathway signaling and promotes genomic instability and tumor growth. The Journal of Clinical Investigation. 120: 1524-34. PMID 20407210 DOI: 10.1172/JCI40908  0.333
2010 Souza GR, Molina JR, Raphael RM, Ozawa MG, Stark DJ, Levin CS, Bronk LF, Ananta JS, Mandelin J, Georgescu MM, Bankson JA, Gelovani JG, Killian TC, Arap W, Pasqualini R. Three-dimensional tissue culture based on magnetic cell levitation. Nature Nanotechnology. 5: 291-6. PMID 20228788 DOI: 10.1038/Nnano.2010.23  0.496
2010 Morales FC, Molina JR, Hayashi Y, Georgescu MM. Overexpression of ezrin inactivates NF2 tumor suppressor in glioblastoma. Neuro-Oncology. 12: 528-39. PMID 20156804 DOI: 10.1093/Neuonc/Nop060  0.544
2008 Georgescu MM, Morales FC, Molina JR, Hayashi Y. Roles of NHERF1/EBP50 in cancer. Current Molecular Medicine. 8: 459-68. PMID 18781953 DOI: 10.2174/156652408785748031  0.552
2005 Fernandez-Zapico ME, Gonzalez-Paz NC, Weiss E, Savoy DN, Molina JR, Fonseca R, Smyrk TC, Chari ST, Urrutia R, Billadeau DD. Ectopic expression of VAV1 reveals an unexpected role in pancreatic cancer tumorigenesis. Cancer Cell. 7: 39-49. PMID 15652748 DOI: 10.1016/J.Ccr.2004.11.024  0.341
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