John Tyson, Ph.D. - Publications

Affiliations: 
Biology Virginia Polytechnic Institute and State University, Blacksburg, VA, United States 
Area:
cell cycle modeling

120 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Dragoi CM, Kaur E, Barr AR, Tyson JJ, Novák B. The oscillation of mitotic kinase governs cell cycle latches in mammalian cells. Journal of Cell Science. PMID 38206091 DOI: 10.1242/jcs.261364  0.736
2023 Xu C, Tyson JJ, Cao Y. Turing-pattern model of scaffolding proteins that establish spatial asymmetry during the cell cycle of . Iscience. 26: 106513. PMID 37128549 DOI: 10.1016/j.isci.2023.106513  0.391
2022 Laomettachit T, Kraikivski P, Tyson JJ. A continuous-time stochastic Boolean model provides a quantitative description of the budding yeast cell cycle. Scientific Reports. 12: 20302. PMID 36434030 DOI: 10.1038/s41598-022-24302-6  0.47
2022 Tyson JJ, Novák B. Time-keeping and decision-making in the cell cycle. Interface Focus. 12: 20210075. PMID 35860005 DOI: 10.1098/rsfs.2021.0075  0.789
2022 Novak B, Tyson JJ. Mitotic kinase oscillation governs the latching of cell cycle switches. Current Biology : Cb. PMID 35504285 DOI: 10.1016/j.cub.2022.04.016  0.729
2022 Tyson JJ. From the Belousov-Zhabotinsky reaction to biochemical clocks, traveling waves and cell cycle regulation. The Biochemical Journal. 479: 185-206. PMID 35098993 DOI: 10.1042/BCJ20210370  0.338
2022 Zhang T, Tyson JJ. Understanding virtual patients efficiently and rigorously by combining machine learning with dynamical modelling. Journal of Pharmacokinetics and Pharmacodynamics. PMID 34985622 DOI: 10.1007/s10928-021-09798-1  0.681
2021 Weston BR, Tyson JJ, Cao Y. Computational modeling of unphosphorylated CtrA: binding in the cell cycle. Iscience. 24: 103413. PMID 34901785 DOI: 10.1016/j.isci.2021.103413  0.351
2021 Novák B, Tyson JJ. Computational modelling of chromosome re-replication in mutant strains of fission yeast. Molecular Biology of the Cell. mbcE20090610. PMID 33534609 DOI: 10.1091/mbc.E20-09-0610  0.762
2021 Novák B, Tyson JJ. Mechanisms of signalling-memory governing progression through the eukaryotic cell cycle. Current Opinion in Cell Biology. 69: 7-16. PMID 33412443 DOI: 10.1016/j.ceb.2020.12.003  0.756
2020 Gallegos JE, Adames NR, Rogers MF, Kraikivski P, Ibele A, Nurzynski-Loth K, Kudlow E, Murali TM, Tyson JJ, Peccoud J. Genetic interactions derived from high-throughput phenotyping of 6589 yeast cell cycle mutants. Npj Systems Biology and Applications. 6: 11. PMID 32376972 DOI: 10.1038/s41540-020-0134-z  0.366
2020 Tyson JJ, Novak B. A Dynamical Paradigm for Molecular Cell Biology. Trends in Cell Biology. PMID 32362451 DOI: 10.1016/J.Tcb.2020.04.002  0.749
2020 Ahmadian M, Tyson JJ, Peccoud J, Cao Y. A hybrid stochastic model of the budding yeast cell cycle. Npj Systems Biology and Applications. 6: 7. PMID 32221305 DOI: 10.1038/s41540-020-0126-z  0.376
2020 Heldt FS, Tyson JJ, Cross FR, Novák B. A Single Light-Responsive Sizer Can Control Multiple-Fission Cycles in Chlamydomonas. Current Biology : Cb. PMID 31928875 DOI: 10.1016/j.cub.2019.12.026  0.773
2019 Ahmadian M, Tyson JJ, Cao Y. A stochastic model of size control in the budding yeast cell cycle. Bmc Bioinformatics. 20: 322. PMID 31216979 DOI: 10.1186/s12859-019-2839-9  0.411
2019 Palmisano A, Hoops S, Watson LT, Jones TC, Tyson JJ, Shaffer CA. Efficiently Encoding Complex Biochemical Models with the Multistate Model Builder (MSMB). Methods in Molecular Biology (Clifton, N.J.). 1945: 119-139. PMID 30945244 DOI: 10.1007/978-1-4939-9102-0_5  0.508
2019 Tyson JJ, Laomettachit T, Kraikivski P. Modeling the dynamic behavior of biochemical regulatory networks. Journal of Theoretical Biology. 462: 514-527. PMID 30502409 DOI: 10.1016/j.jtbi.2018.11.034  0.344
2018 Jones TC, Hoops S, Watson LT, Palmisano A, Tyson JJ, Shaffer CA. JigCell Model Connector: building large molecular network models from components. Simulation. 94: 993-1008. PMID 31303682 DOI: 10.1177/0037549717754121  0.503
2018 Battogtokh D, Tyson JJ. Deciphering the Dynamics of Interlocked Feedback Loops in a Model of the Mammalian Circadian Clock. Biophysical Journal. 115: 2055-2066. PMID 30473017 DOI: 10.1016/j.bpj.2018.10.005  0.312
2018 Heldt FS, Lunstone R, Tyson JJ, Novák B. Dilution and titration of cell-cycle regulators may control cell size in budding yeast. Plos Computational Biology. 14: e1006548. PMID 30356259 DOI: 10.1371/journal.pcbi.1006548  0.761
2018 Novák B, Heldt FS, Tyson JJ. Genome Stability during Cell Proliferation: A Systems Analysis of the Molecular Mechanisms Controlling Progression through the Eukaryotic Cell Cycle. Current Opinion in Systems Biology. 9: 22-31. PMID 30221209 DOI: 10.1016/J.Coisb.2018.02.004  0.752
2017 Chen M, Amos B, Watson LT, Tyson J, Cao Y, Shaffer C, Trosset M, Oguz C, Kakoti G. Quasi-Newton Stochastic Optimization Algorithm for Parameter Estimation of a Stochastic Model of the Budding Yeast Cell Cycle. Ieee/Acm Transactions On Computational Biology and Bioinformatics. PMID 29990127 DOI: 10.1109/Tcbb.2017.2773083  0.502
2017 Hopkins M, Tyson JJ, Novák B. Cell cycle transitions: a common role for stoichiometric inhibitors. Molecular Biology of the Cell. PMID 28931595 DOI: 10.1091/Mbc.E17-06-0349  0.773
2017 Subramanian K, Tyson JJ. Spatiotemporal Models of the Asymmetric Division Cycle of Caulobacter crescentus. Results and Problems in Cell Differentiation. 61: 23-48. PMID 28409299 DOI: 10.1007/978-3-319-53150-2_2  0.401
2017 Oguz C, Watson LT, Baumann WT, Tyson JJ. Predicting network modules of cell cycle regulators using relative protein abundance statistics. Bmc Systems Biology. 11: 30. PMID 28241833 DOI: 10.1186/S12918-017-0409-1  0.577
2016 Barik D, Ball DA, Peccoud J, Tyson JJ. A Stochastic Model of the Yeast Cell Cycle Reveals Roles for Feedback Regulation in Limiting Cellular Variability. Plos Computational Biology. 12: e1005230. PMID 27935947 DOI: 10.1371/Journal.Pcbi.1005230  0.76
2016 Li F, Subramanian K, Chen M, Tyson JJ, Cao Y. A stochastic spatiotemporal model of a response-regulator network in the Caulobacter crescentus cell cycle. Physical Biology. 13: 035007. PMID 27345750 DOI: 10.1088/1478-3975/13/3/035007  0.457
2016 Laomettachit T, Chen KC, Baumann WT, Tyson JJ. A Model of Yeast Cell-Cycle Regulation Based on a Standard Component Modeling Strategy for Protein Regulatory Networks. Plos One. 11: e0153738. PMID 27187804 DOI: 10.1371/Journal.Pone.0153738  0.442
2015 Kraikivski P, Chen KC, Laomettachit T, Murali TM, Tyson JJ. From START to FINISH: computational analysis of cell cycle control in budding yeast. Npj Systems Biology and Applications. 1: 15016. PMID 28725464 DOI: 10.1038/npjsba.2015.16  0.474
2015 Palmisano A, Hoops S, Watson LT, Jones TC, Tyson JJ, Shaffer CA. JigCell Run Manager (JC-RM): a tool for managing large sets of biochemical model parametrizations. Bmc Systems Biology. 9: 95. PMID 26704692 DOI: 10.1186/S12918-015-0237-0  0.482
2015 Adames NR, Schuck PL, Chen KC, Murali TM, Tyson JJ, Peccoud J. Experimental testing of a new integrated model of the budding yeast Start transition. Molecular Biology of the Cell. 26: 3966-84. PMID 26310445 DOI: 10.1091/Mbc.E15-06-0358  0.356
2015 Tavassoly I, Parmar J, Shajahan-Haq AN, Clarke R, Baumann WT, Tyson JJ. Dynamic Modeling of the Interaction Between Autophagy and Apoptosis in Mammalian Cells. Cpt: Pharmacometrics & Systems Pharmacology. 4: 263-72. PMID 26225250 DOI: 10.1002/psp4.29  0.735
2015 Subramanian K, Paul MR, Tyson JJ. Dynamical Localization of DivL and PleC in the Asymmetric Division Cycle of Caulobacter crescentus: A Theoretical Investigation of Alternative Models. Plos Computational Biology. 11: e1004348. PMID 26186202 DOI: 10.1371/Journal.Pcbi.1004348  0.411
2015 Tyson JJ, Novák B. Models in biology: lessons from modeling regulation of the eukaryotic cell cycle. Bmc Biology. 13: 46. PMID 26129844 DOI: 10.1186/S12915-015-0158-9  0.776
2015 Gérard C, Tyson JJ, Coudreuse D, Novák B. Cell cycle control by a minimal Cdk network. Plos Computational Biology. 11: e1004056. PMID 25658582 DOI: 10.1371/Journal.Pcbi.1004056  0.803
2015 Tyson JJ, Novak B. Bistability, oscillations, and traveling waves in frog egg extracts. Bulletin of Mathematical Biology. 77: 796-816. PMID 25185750 DOI: 10.1007/S11538-014-0009-9  0.778
2014 Tyson JJ, Novak B. Control of cell growth, division and death: information processing in living cells. Interface Focus. 4: 20130070. PMID 24904735 DOI: 10.1098/Rsfs.2013.0070  0.723
2014 Oguz C, Palmisano A, Laomettachit T, Watson LT, Baumann WT, Tyson JJ. A stochastic model correctly predicts changes in budding yeast cell cycle dynamics upon periodic expression of CLN2. Plos One. 9: e96726. PMID 24816736 DOI: 10.1371/Journal.Pone.0096726  0.603
2014 Chen C, Baumann WT, Xing J, Xu L, Clarke R, Tyson JJ. Mathematical models of the transitions between endocrine therapy responsive and resistant states in breast cancer. Journal of the Royal Society, Interface / the Royal Society. 11: 20140206. PMID 24806707 DOI: 10.1098/Rsif.2014.0206  0.629
2014 Palmisano A, Hoops S, Watson LT, Jones TC, Tyson JJ, Shaffer CA. Multistate Model Builder (MSMB): a flexible editor for compact biochemical models. Bmc Systems Biology. 8: 42. PMID 24708852 DOI: 10.1186/1752-0509-8-42  0.519
2014 Andrew TM, Amos BD, Easterling DR, Oguz C, Baumann WT, Tyson JJ, Watson LT. Global parameter estimation for a eukaryotic cell cycle model in systems biology Simulation Series. 46: 324-331.  0.311
2013 Parmar JH, Cook KL, Shajahan-Haq AN, Clarke PA, Tavassoly I, Clarke R, Tyson JJ, Baumann WT. Modelling the effect of GRP78 on anti-oestrogen sensitivity and resistance in breast cancer. Interface Focus. 3: 20130012. PMID 24511377 DOI: 10.1098/Rsfs.2013.0012  0.707
2013 Zhang T, Tyson JJ, Novák B. Role for regulated phosphatase activity in generating mitotic oscillations in Xenopus cell-free extracts. Proceedings of the National Academy of Sciences of the United States of America. 110: 20539-44. PMID 24297885 DOI: 10.1073/Pnas.1318065110  0.819
2013 Subramanian K, Paul MR, Tyson JJ. Potential role of a bistable histidine kinase switch in the asymmetric division cycle of Caulobacter crescentus. Plos Computational Biology. 9: e1003221. PMID 24068904 DOI: 10.1371/Journal.Pcbi.1003221  0.329
2013 Ball DA, Adames NR, Reischmann N, Barik D, Franck CT, Tyson JJ, Peccoud J. Measurement and modeling of transcriptional noise in the cell cycle regulatory network. Cell Cycle (Georgetown, Tex.). 12: 3203-18. PMID 24013422 DOI: 10.4161/Cc.26257  0.753
2013 Oguz C, Laomettachit T, Chen KC, Watson LT, Baumann WT, Tyson JJ. Optimization and model reduction in the high dimensional parameter space of a budding yeast cell cycle model. Bmc Systems Biology. 7: 53. PMID 23809412 DOI: 10.1186/1752-0509-7-53  0.506
2013 Poirel CL, Rodrigues RR, Chen KC, Tyson JJ, Murali TM. Top-down network analysis to drive bottom-up modeling of physiological processes. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 20: 409-18. PMID 23641868 DOI: 10.1089/Cmb.2012.0274  0.389
2013 Gérard C, Tyson JJ, Novák B. Minimal models for cell-cycle control based on competitive inhibition and multisite phosphorylations of Cdk substrates. Biophysical Journal. 104: 1367-79. PMID 23528096 DOI: 10.1016/J.Bpj.2013.02.012  0.791
2013 Verdugo A, Vinod PK, Tyson JJ, Novak B. Molecular mechanisms creating bistable switches at cell cycle transitions. Open Biology. 3: 120179. PMID 23486222 DOI: 10.1098/Rsob.120179  0.76
2013 Tyson JJ, Novák B. Irreversible Transitions, Bistability and Checkpoint Controls in the Eukaryotic Cell Cycle: A Systems-Level Understanding Handbook of Systems Biology. 265-285. DOI: 10.1016/B978-0-12-385944-0.00014-9  0.309
2012 Hong T, Xing J, Li L, Tyson JJ. A simple theoretical framework for understanding heterogeneous differentiation of CD4+ T cells. Bmc Systems Biology. 6: 66. PMID 22697466 DOI: 10.1186/1752-0509-6-66  0.675
2012 Fu Y, Glaros T, Zhu M, Wang P, Wu Z, Tyson JJ, Li L, Xing J. Network topologies and dynamics leading to endotoxin tolerance and priming in innate immune cells. Plos Computational Biology. 8: e1002526. PMID 22615556 DOI: 10.1371/Journal.Pcbi.1002526  0.698
2012 Clarke R, Cook KL, Hu R, Facey CO, Tavassoly I, Schwartz JL, Baumann WT, Tyson JJ, Xuan J, Wang Y, Wärri A, Shajahan AN. Endoplasmic reticulum stress, the unfolded protein response, autophagy, and the integrated regulation of breast cancer cell fate. Cancer Research. 72: 1321-31. PMID 22422988 DOI: 10.1158/0008-5472.Can-11-3213  0.73
2012 Hancioglu B, Tyson JJ. A mathematical model of mitotic exit in budding yeast: the role of Polo kinase. Plos One. 7: e30810. PMID 22383977 DOI: 10.1371/journal.pone.0030810  0.375
2012 Liu Z, Pu Y, Li F, Shaffer CA, Hoops S, Tyson JJ, Cao Y. Hybrid modeling and simulation of stochastic effects on progression through the eukaryotic cell cycle. The Journal of Chemical Physics. 136: 034105. PMID 22280742 DOI: 10.1063/1.3677190  0.36
2011 Clarke R, Shajahan AN, Wang Y, Tyson JJ, Riggins RB, Weiner LM, Bauman WT, Xuan J, Zhang B, Facey C, Aiyer H, Cook K, Hickman FE, Tavassoly I, Verdugo A, et al. Endoplasmic reticulum stress, the unfolded protein response, and gene network modeling in antiestrogen resistant breast cancer. Hormone Molecular Biology and Clinical Investigation. 5: 35-44. PMID 23930139 DOI: 10.1515/Hmbci.2010.073  0.739
2011 Ball DA, Marchand J, Poulet M, Baumann WT, Chen KC, Tyson JJ, Peccoud J. Oscillatory dynamics of cell cycle proteins in single yeast cells analyzed by imaging cytometry. Plos One. 6: e26272. PMID 22046265 DOI: 10.1371/Journal.Pone.0026272  0.367
2011 Hong T, Xing J, Li L, Tyson JJ. A mathematical model for the reciprocal differentiation of T helper 17 cells and induced regulatory T cells. Plos Computational Biology. 7: e1002122. PMID 21829337 DOI: 10.1371/Journal.Pcbi.1002122  0.679
2011 Tyson JJ, Baumann WT, Chen C, Verdugo A, Tavassoly I, Wang Y, Weiner LM, Clarke R. Dynamic modelling of oestrogen signalling and cell fate in breast cancer cells. Nature Reviews. Cancer. 11: 523-32. PMID 21677677 DOI: 10.1038/Nrc3081  0.72
2011 He E, Kapuy O, Oliveira RA, Uhlmann F, Tyson JJ, Novák B. System-level feedbacks make the anaphase switch irreversible. Proceedings of the National Academy of Sciences of the United States of America. 108: 10016-21. PMID 21617094 DOI: 10.1073/Pnas.1102106108  0.692
2011 Tyson JJ, Novak B. Cell cycle: who turns the crank? Current Biology : Cb. 21: R185-7. PMID 21377093 DOI: 10.1016/J.Cub.2011.01.042  0.765
2011 Ball DA, Ahn TH, Wang P, Chen KC, Cao Y, Tyson JJ, Peccoud J, Baumann WT. Stochastic exit from mitosis in budding yeast: model predictions and experimental observations. Cell Cycle (Georgetown, Tex.). 10: 999-1009. PMID 21350333 DOI: 10.4161/Cc.10.6.14966  0.346
2011 Singhania R, Sramkoski RM, Jacobberger JW, Tyson JJ. A hybrid model of mammalian cell cycle regulation. Plos Computational Biology. 7: e1001077. PMID 21347318 DOI: 10.1371/Journal.Pcbi.1001077  0.42
2010 Barik D, Baumann WT, Paul MR, Novak B, Tyson JJ. A model of yeast cell-cycle regulation based on multisite phosphorylation. Molecular Systems Biology. 6: 405. PMID 20739927 DOI: 10.1038/Msb.2010.55  0.844
2010 Novak B, Kapuy O, Domingo-Sananes MR, Tyson JJ. Regulated protein kinases and phosphatases in cell cycle decisions. Current Opinion in Cell Biology. 22: 801-8. PMID 20678910 DOI: 10.1016/J.Ceb.2010.07.001  0.758
2010 Randhawa R, Shaffer CA, Tyson JJ. Model composition for macromolecular regulatory networks. Ieee/Acm Transactions On Computational Biology and Bioinformatics / Ieee, Acm. 7: 278-87. PMID 20431147 DOI: 10.1109/Tcbb.2008.64  0.39
2010 Tyson JJ, Novák B. Functional motifs in biochemical reaction networks. Annual Review of Physical Chemistry. 61: 219-40. PMID 20055671 DOI: 10.1146/Annurev.Physchem.012809.103457  0.756
2009 Su J, Zhang T, Tyson J, Li L. The interleukin-1 receptor-associated kinase M selectively inhibits the alternative, instead of the classical NFkappaB pathway. Journal of Innate Immunity. 1: 164-74. PMID 19809574 DOI: 10.1159/000158541  0.686
2009 Kapuy O, He E, López-Avilés S, Uhlmann F, Tyson JJ, Novák B. System-level feedbacks control cell cycle progression. Febs Letters. 583: 3992-8. PMID 19703449 DOI: 10.1016/J.Febslet.2009.08.023  0.772
2009 Li S, Brazhnik P, Sobral B, Tyson JJ. Temporal controls of the asymmetric cell division cycle in Caulobacter crescentus. Plos Computational Biology. 5: e1000463. PMID 19680425 DOI: 10.1371/Journal.Pcbi.1000463  0.667
2009 Zhang T, Brazhnik P, Tyson JJ. Computational analysis of dynamical responses to the intrinsic pathway of programmed cell death. Biophysical Journal. 97: 415-34. PMID 19619456 DOI: 10.1016/J.Bpj.2009.04.053  0.746
2009 Kapuy O, Barik D, Sananes MR, Tyson JJ, Novák B. Bistability by multiple phosphorylation of regulatory proteins. Progress in Biophysics and Molecular Biology. 100: 47-56. PMID 19523976 DOI: 10.1016/J.Pbiomolbio.2009.06.004  0.789
2009 Zwolak J, Adjerid N, Bagci EZ, Tyson JJ, Sible JC. A quantitative model of the effect of unreplicated DNA on cell cycle progression in frog egg extracts. Journal of Theoretical Biology. 260: 110-20. PMID 19490919 DOI: 10.1016/J.Jtbi.2009.05.018  0.85
2009 Shaffer CA, Zwolak JW, Randhawa R, Tyson JJ. Modeling molecular regulatory networks with JigCell and PET. Methods in Molecular Biology (Clifton, N.J.). 500: 81-111. PMID 19399431 DOI: 10.1007/978-1-59745-525-1_4  0.807
2009 Kar S, Baumann WT, Paul MR, Tyson JJ. Exploring the roles of noise in the eukaryotic cell cycle. Proceedings of the National Academy of Sciences of the United States of America. 106: 6471-6. PMID 19246388 DOI: 10.1073/Pnas.0810034106  0.734
2009 Csikász-Nagy A, Kapuy O, Tóth A, Pál C, Jensen LJ, Uhlmann F, Tyson JJ, Novák B. Cell cycle regulation by feed-forward loops coupling transcription and phosphorylation. Molecular Systems Biology. 5: 236. PMID 19156128 DOI: 10.1038/Msb.2008.73  0.832
2008 Novák B, Tyson JJ. Design principles of biochemical oscillators. Nature Reviews. Molecular Cell Biology. 9: 981-91. PMID 18971947 DOI: 10.1038/Nrm2530  0.722
2008 Tyson JJ, Novak B. Temporal organization of the cell cycle. Current Biology : Cb. 18: R759-R768. PMID 18786381 DOI: 10.1016/J.Cub.2008.07.001  0.783
2008 Csikász-Nagy A, Novák B, Tyson JJ. Reverse engineering models of cell cycle regulation. Advances in Experimental Medicine and Biology. 641: 88-97. PMID 18783174 DOI: 10.1007/978-0-387-09794-7_7  0.827
2008 Barik D, Paul MR, Baumann WT, Cao Y, Tyson JJ. Stochastic simulation of enzyme-catalyzed reactions with disparate timescales. Biophysical Journal. 95: 3563-74. PMID 18621809 DOI: 10.1529/Biophysj.108.129155  0.674
2008 Tyson JJ, Albert R, Goldbeter A, Ruoff P, Sible J. Biological switches and clocks. Journal of the Royal Society, Interface / the Royal Society. 5: S1-8. PMID 18522926 DOI: 10.1098/Rsif.2008.0179.Focus  0.354
2008 Li S, Brazhnik P, Sobral B, Tyson JJ. A quantitative study of the division cycle of Caulobacter crescentus stalked cells. Plos Computational Biology. 4: e9. PMID 18225942 DOI: 10.1371/Journal.Pcbi.0040009  0.672
2008 Csikász-Nagy A, Gyorffy B, Alt W, Tyson JJ, Novák B. Spatial controls for growth zone formation during the fission yeast cell cycle. Yeast (Chichester, England). 25: 59-69. PMID 17957823 DOI: 10.1002/Yea.1571  0.801
2008 Sabouri-Ghomi M, Ciliberto A, Kar S, Novak B, Tyson JJ. Antagonism and bistability in protein interaction networks. Journal of Theoretical Biology. 250: 209-18. PMID 17950756 DOI: 10.1016/J.Jtbi.2007.09.001  0.805
2008 Panning TD, Watson LT, Allen NA, Chen KC, Shaffer CA, Tyson JJ. Deterministic parallel global parameter estimation for a model of the budding yeast cell cycle Journal of Global Optimization. 40: 719-738. DOI: 10.1007/S10898-007-9273-7  0.486
2007 Calzone L, Thieffry D, Tyson JJ, Novak B. Dynamical modeling of syncytial mitotic cycles in Drosophila embryos. Molecular Systems Biology. 3: 131. PMID 17667953 DOI: 10.1038/Msb4100171  0.816
2007 Novak B, Tyson JJ, Gyorffy B, Csikasz-Nagy A. Irreversible cell-cycle transitions are due to systems-level feedback. Nature Cell Biology. 9: 724-8. PMID 17603504 DOI: 10.1038/Ncb0707-724  0.814
2007 Csikász-Nagy A, Kapuy O, Gyorffy B, Tyson JJ, Novák B. Modeling the septation initiation network (SIN) in fission yeast cells. Current Genetics. 51: 245-55. PMID 17340144 DOI: 10.1007/S00294-007-0123-4  0.843
2007 Zhang T, Brazhnik P, Tyson JJ. Exploring mechanisms of the DNA-damage response: p53 pulses and their possible relevance to apoptosis. Cell Cycle (Georgetown, Tex.). 6: 85-94. PMID 17245126 DOI: 10.4161/Cc.6.1.3705  0.709
2007 Hong CI, Conrad ED, Tyson JJ. A proposal for robust temperature compensation of circadian rhythms. Proceedings of the National Academy of Sciences of the United States of America. 104: 1195-200. PMID 17229851 DOI: 10.1073/Pnas.0601378104  0.667
2007 Sible JC, Tyson JJ. Mathematical modeling as a tool for investigating cell cycle control networks. Methods (San Diego, Calif.). 41: 238-47. PMID 17189866 DOI: 10.1016/J.Ymeth.2006.08.003  0.41
2007 Panning TD, Watson LT, Shaffer CA, Tyson JJ. A mathematical programming formulation for the budding yeast cell cycle Simulation. 83: 497-514. DOI: 10.1177/0037549707085075  0.505
2006 Vass MT, Shaffer CA, Ramakrishnan N, Watson LT, Tyson JJ. The JigCell model builder: a spreadsheet interface for creating biochemical reaction network models. Ieee/Acm Transactions On Computational Biology and Bioinformatics / Ieee, Acm. 3: 155-64. PMID 17048401 DOI: 10.1109/Tcbb.2006.27  0.504
2006 Allen NA, Chen KC, Shaffer CA, Tyson JJ, Watson LT. Computer evaluation of network dynamics models with application to cell cycle control in budding yeast Iee Proceedings Systems Biology. 153: 13-21. PMID 16983831 DOI: 10.1049/ip-syb:20050029  0.587
2006 Battogtokh D, Aihara K, Tyson JJ. Synchronization of eukaryotic cells by periodic forcing. Physical Review Letters. 96: 148102. PMID 16712125 DOI: 10.1103/PhysRevLett.96.148102  0.369
2006 Csikász-Nagy A, Battogtokh D, Chen KC, Novák B, Tyson JJ. Analysis of a generic model of eukaryotic cell-cycle regulation. Biophysical Journal. 90: 4361-79. PMID 16581849 DOI: 10.1529/Biophysj.106.081240  0.847
2006 Brazhnik P, Tyson JJ. Cell cycle control in bacteria and yeast: a case of convergent evolution? Cell Cycle (Georgetown, Tex.). 5: 522-9. PMID 16552176  0.399
2006 Battogtokh D, Tyson JJ. Periodic forcing of a mathematical model of the eukaryotic cell cycle. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 73: 011910. PMID 16486188 DOI: 10.1103/PhysRevE.73.011910  0.387
2005 Zwolak JW, Tyson JJ, Watson LT. Globally optimised parameters for a model of mitotic control in frog egg extracts. Systems Biology. 152: 81-92. PMID 17044236 DOI: 10.1049/ip-syb:20045032  0.786
2005 Ciliberto A, Lukács A, Tóth A, Tyson JJ, Novák B. Rewiring the exit from mitosis. Cell Cycle (Georgetown, Tex.). 4: 1107-12. PMID 15970669  0.757
2005 Zwolak JW, Tyson JJ, Watson LT. Parameter estimation for a mathematical model of the cell cycle in frog eggs. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 12: 48-63. PMID 15725733 DOI: 10.1089/Cmb.2005.12.48  0.785
2005 Ciliberto A, Novak B, Tyson JJ. Steady states and oscillations in the p53/Mdm2 network. Cell Cycle (Georgetown, Tex.). 4: 488-93. PMID 15725723 DOI: 10.4161/Cc.4.3.1548  0.717
2004 Battogtokh D, Tyson JJ. Bifurcation analysis of a model of the budding yeast cell cycle. Chaos (Woodbury, N.Y.). 14: 653-61. PMID 15446975 DOI: 10.1063/1.1780011  0.329
2004 Novák B, Tyson JJ. A model for restriction point control of the mammalian cell cycle. Journal of Theoretical Biology. 230: 563-79. PMID 15363676 DOI: 10.1016/J.Jtbi.2004.04.039  0.787
2004 Vass M, Allen N, Shaffer CA, Ramakrishnan N, Watson LT, Tyson JJ. the JigCell model builder and run manager. Bioinformatics (Oxford, England). 20: 3680-1. PMID 15273159 DOI: 10.1093/Bioinformatics/Bth422  0.475
2004 Chen KC, Calzone L, Csikasz-Nagy A, Cross FR, Novak B, Tyson JJ. Integrative analysis of cell cycle control in budding yeast. Molecular Biology of the Cell. 15: 3841-62. PMID 15169868 DOI: 10.1091/Mbc.E03-11-0794  0.833
2004 Sveiczer A, Tyson JJ, Novak B. Modelling the fission yeast cell cycle. Briefings in Functional Genomics & Proteomics. 2: 298-307. PMID 15163365 DOI: 10.1093/Bfgp/2.4.298  0.786
2004 Zwolak JW, Tyson JJ, Watson LT. Finding all steady state solutions of chemical kinetic models Nonlinear Analysis: Real World Applications. 5: 801-814. DOI: 10.1016/J.Nonrwa.2004.02.002  0.77
2004 He J, Sosonkina M, Shaffer CA, Tyson JJ, Watson LT, Zwolak JW. A hierarchical parallel scheme for global parameter estimation in systems biology Proceedings - International Parallel and Distributed Processing Symposium, Ipdps 2004 (Abstracts and Cd-Rom). 18: 571-579.  0.751
2003 Ciliberto A, Novak B, Tyson JJ. Mathematical model of the morphogenesis checkpoint in budding yeast. The Journal of Cell Biology. 163: 1243-54. PMID 14691135 DOI: 10.1083/Jcb.200306139  0.795
2003 Novák B, Tyson JJ. Modelling the controls of the eukaryotic cell cycle Biochemical Society Transactions. 31: 1526-1529. PMID 14641104 DOI: 10.1042/Bst0311526  0.788
2003 Allen NA, Calzone L, Chen KC, Ciliberto A, Ramakrishnan N, Shaffer CA, Sible JC, Tyson JJ, Vass MT, Watson LT, Zwolak JW. Modeling regulatory networks at Virginia Tech. Omics : a Journal of Integrative Biology. 7: 285-99. PMID 14583117 DOI: 10.1089/153623103322452404  0.818
2003 Tyson JJ, Chen KC, Novak B. Sniffers, buzzers, toggles and blinkers: dynamics of regulatory and signaling pathways in the cell. Current Opinion in Cell Biology. 15: 221-31. PMID 12648679 DOI: 10.1016/S0955-0674(03)00017-6  0.763
2003 Sha W, Moore J, Chen K, Lassaletta AD, Yi CS, Tyson JJ, Sible JC. Hysteresis drives cell-cycle transitions in Xenopus laevis egg extracts. Proceedings of the National Academy of Sciences of the United States of America. 100: 975-80. PMID 12509509 DOI: 10.1073/Pnas.0235349100  0.376
2002 Tyson JJ, Csikasz-Nagy A, Novak B. The dynamics of cell cycle regulation. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 24: 1095-109. PMID 12447975 DOI: 10.1002/Bies.10191  0.848
2001 Novak B, Pataki Z, Ciliberto A, Tyson JJ. Mathematical model of the cell division cycle of fission yeast. Chaos (Woodbury, N.Y.). 11: 277-286. PMID 12779461 DOI: 10.1063/1.1345725  0.775
1979 Tyson J, Garcia-Herdugo G, Sachsenmaier W. Control of nuclear division in Physarum polycephalum: Comparison of cycloheximide pulse treatment, UV irradiation, and heat shock Experimental Cell Research. 119: 87-98. PMID 761604 DOI: 10.1016/0014-4827(79)90338-0  0.302
1979 Tyson J, Sachsenmaier W. Derepression as a model for control of the DNA-division cycle in eukaryotes. Journal of Theoretical Biology. 79: 275-280. PMID 522494 DOI: 10.1016/0022-5193(79)90346-1  0.438
1978 Tyson J, Sachsenmaier W. Is nuclear division in Physarum controlled by a continuous limit cycle oscillator Journal of Theoretical Biology. 73: 723-738. PMID 703344 DOI: 10.1016/0022-5193(78)90133-9  0.347
1975 Tyson J, Kauffman S. Control of mitosis by a continuous biochemical oscillation: Synchronization; spatially inhomogeneous oscillations Journal of Mathematical Biology. 1: 289-310. DOI: 10.1007/Bf00279848  0.365
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