Eric C. Frey - Publications

Affiliations: 
2002 University of North Carolina, Chapel Hill, Chapel Hill, NC 
 2002- Electrical and Computer Engineering Johns Hopkins University, Baltimore, MD 
Area:
Radiology, Biomedical Engineering, Oncology, Alternative Medicine

154 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Li Y, Brown JL, Xu J, Chen J, Ghaly M, Dugan M, Cao X, Du Y, Fahey FH, Bolch W, Sgouros G, Frey EC. Girth-based administered activity for pediatric Tc-DMSA SPECT. Medical Physics. PMID 37482927 DOI: 10.1002/mp.16602  0.479
2022 Chen J, Frey EC, He Y, Segars WP, Li Y, Du Y. TransMorph: Transformer for unsupervised medical image registration. Medical Image Analysis. 82: 102615. PMID 36156420 DOI: 10.1016/j.media.2022.102615  0.525
2021 Chen J, Li Y, Luna LP, Chung HW, Rowe SP, Du Y, Solnes LB, Frey EC. Learning Fuzzy Clustering for SPECT/CT Segmentation via Convolutional Neural Networks. Medical Physics. PMID 33905560 DOI: 10.1002/mp.14903  0.468
2021 Li Y, Chen J, Brown JL, Treves ST, Cao X, Fahey FH, Sgouros G, Bolch WE, Frey EC. DeepAMO: a multi-slice, multi-view anthropomorphic model observer for visual detection tasks performed on volume images. Journal of Medical Imaging (Bellingham, Wash.). 8: 041204. PMID 33521164 DOI: 10.1117/1.JMI.8.4.041204  0.523
2020 Brown JL, Sexton-Stallone B, Li Y, Frey EC, Treves ST, Fahey FH, Plyku D, Cao X, Sgouros G, Bolch WE. Body morphometry appropriate computational phantoms for dose and risk optimization in pediatric renal imaging with Tc-99m DMSA and Tc-99m MAG3. Physics in Medicine and Biology. 65: 235026. PMID 33245053 DOI: 10.1088/1361-6560/Abb1Da  0.4
2020 Chen J, Li Y, Du Y, Frey EC. Generating Anthropomorphic Phantoms Using Fully Unsupervised Deformable Image Registration with Convolutional Neural Networks. Medical Physics. PMID 33078422 DOI: 10.1002/mp.14545  0.562
2020 Rahman A, Zhu Y, Clarkson E, Kupinski MA, Frey EC, Jha AK. Fisher information analysis of list-mode SPECT emission data for joint estimation of activity and attenuation distribution. Inverse Problems. 36. PMID 33071423 DOI: 10.1088/1361-6420/ab958b  0.331
2020 St James S, Bednarz B, Benedict S, Buchsbaum JC, Dewaraja Y, Frey E, Hobbs R, Grudzinski J, Roncali E, Sgouros G, Capala J, Xiao Y. Current Status of Radiopharmaceutical Therapy. International Journal of Radiation Oncology, Biology, Physics. PMID 32805300 DOI: 10.1016/J.Ijrobp.2020.08.035  0.396
2020 Rahman MA, Zhu Y, Clarkson E, Kupinski MA, Frey EC, Jha AK. Fisher information analysis of list-mode SPECT emission data for joint estimation of activity and attenuation distribution Inverse Problems. 36: 084002. DOI: 10.1088/1361-6420/Ab958B  0.44
2019 Li Y, O'Reilly S, Plyku D, Ted Treves S, Fahey F, Du Y, Cao X, Sexton-Stallone B, Brown J, Sgouros G, Bolch WE, Frey EC. Current Pediatric Administered Activity Guidelines for Tc-DMSA SPECT Based on Patient Weight Do Not Provide the Same Task-based Image Quality. Medical Physics. PMID 31448427 DOI: 10.1002/Mp.13787  0.373
2019 He B, Frey E, Sgouros G, Ghaly M, Tworowska I, Delpassand E. Development and Validation of Methods for Quantitative In Vivo SPECT of Pb-212 Journal of Medical Imaging and Radiation Sciences. 50: S33. DOI: 10.1016/J.Jmir.2019.03.100  0.312
2018 Karimi Ghodoosi E, D'Alessandria C, Li Y, Bartel A, Köhner M, Höllriegl V, Navab N, Eiber M, Li WB, Frey E, Ziegler S. The effect of attenuation map, scatter energy window width, and volume of interest on the calibration factor calculation in quantitative Lu SPECT imaging: Simulation and phantom study. Physica Medica : Pm : An International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (Aifb). 56: 74-80. PMID 30527092 DOI: 10.1016/J.Ejmp.2018.11.009  0.47
2018 Lodge MA, Leal JP, Rahmim A, Sunderland JJ, Frey EC. Measuring PET Spatial Resolution Using a Cylinder Phantom Positioned at an Oblique Angle. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 29903932 DOI: 10.2967/Jnumed.118.209593  0.409
2018 Li Y, O'Reilly SE, Plyku D, Treves ST, Du Y, Fahey FH, Cao X, Jha AK, Sgouros G, Bolch WE, Frey EC. A projection image database to investigate factors affecting image quality in weight-based dosing: application to pediatric renal SPECT. Physics in Medicine and Biology. PMID 29893291 DOI: 10.1088/1361-6560/Aacbf0  0.398
2017 Jones KM, Solnes LB, Rowe SP, Gorin MA, Sheikhbahaei S, Fung G, Frey EC, Allaf ME, Du Y, Javadi MS. Use of quantitative SPECT/CT reconstruction in 99mTc-sestamibi imaging of patients with renal masses. Annals of Nuclear Medicine. PMID 29214562 DOI: 10.1007/S12149-017-1222-Z  0.372
2017 Elshahaby FEA, Jha AK, Ghaly M, Frey EC. A comparison of resampling schemes for estimating model observer performance with small ensembles. Physics in Medicine and Biology. 62: 7300-7320. PMID 28829044 DOI: 10.1088/1361-6560/Aa807A  0.33
2017 Jha AK, Frey E. No-gold-standard evaluation of image-acquisition methods using patient data. Proceedings of Spie--the International Society For Optical Engineering. 10136. PMID 28596636 DOI: 10.1117/12.2255902  0.439
2017 Jha AK, Mena E, Caffo B, Ashrafinia S, Rahmim A, Frey E, Subramaniam RM. Practical no-gold-standard evaluation framework for quantitative imaging methods: application to lesion segmentation in positron emission tomography. Journal of Medical Imaging (Bellingham, Wash.). 4: 011011. PMID 28331883 DOI: 10.1117/1.Jmi.4.1.011011  0.402
2017 Fahey FH, Goodkind AB, Plyku D, Khamwan K, O'Reilly SE, Cao X, Frey EC, Li Y, Bolch WE, Sgouros G, Treves ST. Dose Estimation in Pediatric Nuclear Medicine. Seminars in Nuclear Medicine. 47: 118-125. PMID 28237000 DOI: 10.1053/J.Semnuclmed.2016.10.006  0.34
2017 Vicente EM, Lodge MA, Rowe SP, Wahl RL, Frey EC. Simplifying Volumes-of-Interest (VOIs) definition in quantitative SPECT: beyond manual definition of 3D whole-organ VOIs. Medical Physics. PMID 28207950 DOI: 10.1002/Mp.12164  0.342
2016 Yue J, Hobbs R, Sgouros G, Frey E. SU-F-J-08: Quantitative SPECT Imaging of Ra-223 in a Phantom. Medical Physics. 43: 3407. PMID 28048785 DOI: 10.1118/1.4955916  0.389
2016 Li X, Jha A, Ghaly M, Elshahaby F, Links J, Frey E. Use of Sub-ensembles and Multi-template Observers to Evaluate Detection Task Performance for Data That are Not Multivariate Normal. Ieee Transactions On Medical Imaging. PMID 28026757 DOI: 10.1109/Tmi.2016.2643684  0.398
2016 Yue J, Mauxion T, Reyes DK, Lodge MA, Hobbs RF, Rong X, Dong Y, Herman JM, Wahl RL, Geschwind JH, Frey EC. Comparison of quantitative Y-90 SPECT and non-time-of-flight PET imaging in post-therapy radioembolization of liver cancer. Medical Physics. 43: 5779. PMID 27782730 DOI: 10.1118/1.4962472  0.613
2016 Zimmerman BE, Grošev D, Buvat I, Coca Pérez MA, Frey EC, Green A, Krisanachinda A, Lassmann M, Ljungberg M, Pozzo L, Quadir KA, Terán Gretter MA, Van Staden J, Poli GL. Multi-centre evaluation of accuracy and reproducibility of planar and SPECT image quantification: An IAEA phantom study. Zeitschrift Fur Medizinische Physik. PMID 27105765 DOI: 10.1016/J.Zemedi.2016.03.008  0.467
2016 Jha AK, Caffo B, Frey EC. A no-gold-standard technique for objective assessment of quantitative nuclear-medicine imaging methods. Physics in Medicine and Biology. 61: 2780-2800. PMID 26982626 DOI: 10.1088/0031-9155/61/7/2780  0.46
2016 O'Reilly SE, Plyku D, Sgouros G, Fahey FH, Ted Treves S, Frey EC, Bolch WE. A risk index for pediatric patients undergoing diagnostic imaging with (99m)Tc-dimercaptosuccinic acid that accounts for body habitus. Physics in Medicine and Biology. 61: 2319-32. PMID 26930549 DOI: 10.1088/0031-9155/61/6/2319  0.387
2016 Ghaly M, Du Y, Links JM, Frey EC. Collimator optimization in myocardial perfusion SPECT using the ideal observer and realistic background variability for lesion detection and joint detection and localization tasks. Physics in Medicine and Biology. 61: 2048-66. PMID 26895287 DOI: 10.1088/0031-9155/61/5/2048  0.427
2016 Ghaly M, Links JM, Frey EC. Collimator optimization and collimator-detector response compensation in myocardial perfusion SPECT using the ideal observer with and without model mismatch and an anthropomorphic model observer. Physics in Medicine and Biology. 61: 2109-23. PMID 26894376 DOI: 10.1088/0031-9155/61/5/2109  0.424
2016 Elshahaby FE, Ghaly M, Jha AK, Frey EC. Factors affecting the normality of channel outputs of channelized model observers: an investigation using realistic myocardial perfusion SPECT images. Journal of Medical Imaging (Bellingham, Wash.). 3: 015503. PMID 26839913 DOI: 10.1117/1.Jmi.3.1.015503  0.31
2016 Yue J, Mauxion T, Reyes DK, Lodge MA, Hobbs RF, Rong X, Dong Y, Herman JM, Wahl RL, Geschwind JFH, Frey EC. Comparison of quantitative Y-90 SPECT and non-time-of-flight PET imaging in post-therapy radioembolization of liver cancer Medical Physics. 43: 5779-5790. DOI: 10.1118/1.4962472  0.568
2016 Kupinski MK, Clarkson E, Ghaly M, Frey EC. Applying the J-optimal channelized quadratic observer to SPECT myocardial perfusion defect detection Progress in Biomedical Optics and Imaging - Proceedings of Spie. 9787. DOI: 10.1117/12.2217846  0.323
2015 Jha AK, Song N, Caffo B, Frey EC. Objective evaluation of reconstruction methods for quantitative SPECT imaging in the absence of ground truth. Proceedings of Spie--the International Society For Optical Engineering. 9416: 94161K. PMID 26430292 DOI: 10.1117/12.2081286  0.61
2015 Jha AK, Frey EC. Estimating ROI activity concentration with photon-processing and photon-counting SPECT imaging systems. Proceedings of Spie--the International Society For Optical Engineering. 9412: 94120R. PMID 26430291 DOI: 10.1117/12.2082278  0.394
2015 Jha AK, Barrett HH, Frey EC, Clarkson E, Caucci L, Kupinski MA. Singular value decomposition for photon-processing nuclear imaging systems and applications for reconstruction and computing null functions. Physics in Medicine and Biology. 60: 7359-85. PMID 26350439 DOI: 10.1088/0031-9155/60/18/7359  0.429
2015 Ghaly M, Links JM, Frey EC. Optimization and comparison of simultaneous and separate acquisition protocols for dual isotope myocardial perfusion SPECT. Physics in Medicine and Biology. 60: 5083-101. PMID 26083239 DOI: 10.1088/0031-9155/60/13/5083  0.477
2015 Ghaly M, Links JM, Frey E. Optimization of energy window and evaluation of scatter compensation methods in myocardial perfusion SPECT using the ideal observer with and without model mismatch and an anthropomorphic model observer. Journal of Medical Imaging (Bellingham, Wash.). 2. PMID 26029730 DOI: 10.1117/1.Jmi.2.1.015502  0.498
2015 Rowe SP, Vicente E, Anizan N, Wang H, Leal JP, Lodge MA, Frey EC, Wahl RL. Repeatability of Radiotracer Uptake in Normal Abdominal Organs with ¹¹¹In-Pentetreotide Quantitative SPECT/CT. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 56: 985-8. PMID 25977467 DOI: 10.2967/Jnumed.115.155358  0.355
2015 Hossain J, Du Y, Links J, Rahmim A, Karakatsanis N, Akhbardeh A, Lyons J, Frey EC. Estimation of dynamic time activity curves from dynamic cardiac SPECT imaging. Physics in Medicine and Biology. 60: 3193-208. PMID 25813219 DOI: 10.1088/0031-9155/60/8/3193  0.394
2015 Lee TS, Frey EC, Tsui BM. Development of 4D mathematical observer models for the task-based evaluation of gated myocardial perfusion SPECT. Physics in Medicine and Biology. 60: 2751-63. PMID 25768980 DOI: 10.1088/0031-9155/60/7/2751  0.418
2015 Anizan N, Wang H, Zhou XC, Wahl RL, Frey EC. Factors affecting the repeatability of gamma camera calibration for quantitative imaging applications using a sealed source. Physics in Medicine and Biology. 60: 1325-37. PMID 25592130 DOI: 10.1088/0031-9155/60/3/1325  0.33
2015 Ekjeen T, Tocharoenchai C, Pusuwan P, Fung GS, Ghaly M, Du Y, Frey EC. Optimization and evaluation of reconstruction-based compensation methods and reconstruction parameters for Tc-99m MIBI parathyroid SPECT. Physica Medica : Pm : An International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (Aifb). 31: 159-66. PMID 25555904 DOI: 10.1016/J.Ejmp.2014.12.005  0.431
2015 Elshahaby FEA, Ghaly M, Jha AK, Frey EC. The effect of signal variability on the histograms of anthropomorphic channel outputs: Factors resulting in non-normally distributed data Progress in Biomedical Optics and Imaging - Proceedings of Spie. 9416. DOI: 10.1117/12.2081629  0.354
2015 Ghaly M, Links JM, Frey E. Optimization of energy window and evaluation of scatter compensation methods in MPS using the ideal observer with model mismatch Progress in Biomedical Optics and Imaging - Proceedings of Spie. 9416. DOI: 10.1117/12.2081043  0.484
2015 Yue J, Frey E, Mauxion T, Josefsson A, Sgouros G, Hobbs R. Potential for Quantitative Imaging of Ra-223 International Journal of Radiation Oncology*Biology*Physics. 93: E237. DOI: 10.1016/J.Ijrobp.2015.07.1144  0.332
2014 Anizan N, Wang H, Zhou XC, Hobbs RF, Wahl RL, Frey EC. Factors affecting the stability and repeatability of gamma camera calibration for quantitative imaging applications based on a retrospective review of clinical data. Ejnmmi Research. 4: 67. PMID 26116127 DOI: 10.1186/S13550-014-0067-X  0.456
2014 Cheng L, Hobbs RF, Sgouros G, Frey EC. Development and evaluation of convergent and accelerated penalized SPECT image reconstruction methods for improved dose-volume histogram estimation in radiopharmaceutical therapy. Medical Physics. 41: 112507. PMID 25370666 DOI: 10.1118/1.4897613  0.644
2014 Ghaly M, Du Y, Fung GS, Tsui BM, Links JM, Frey E. Design of a digital phantom population for myocardial perfusion SPECT imaging research. Physics in Medicine and Biology. 59: 2935-53. PMID 24841729 DOI: 10.1088/0031-9155/59/12/2935  0.453
2014 Du Y, Bhattacharya M, Frey EC. Simultaneous Tc-99m/I-123 dual-radionuclide myocardial perfusion/innervation imaging using Siemens IQ-SPECT with SMARTZOOM collimator. Physics in Medicine and Biology. 59: 2813-28. PMID 24819280 DOI: 10.1088/0031-9155/59/11/2813  0.53
2014 Du Y, Links JM, Becker L, DiPaula AF, Frank T, Schuleri KH, Lardo AC, Frey EC. Evaluation of simultaneous 201Tl/99mTc dual-isotope cardiac SPECT imaging with model-based crosstalk compensation using canine studies. Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology. 21: 329-40. PMID 24366822 DOI: 10.1007/S12350-013-9842-8  0.466
2013 Rong X, Ghaly M, Frey EC. Optimization of energy window for (90) Y bremsstrahlung SPECT imaging for detection tasks using the ideal observer with model-mismatch. Medical Physics. 40. PMID 28518770 DOI: 10.1118/1.4805095  0.588
2013 Dewaraja YK, Ljungberg M, Green AJ, Zanzonico PB, Frey EC, Bolch WE, Brill AB, Dunphy M, Fisher DR, Howell RW, Meredith RF, Sgouros G, Wessels BW. MIRD pamphlet No. 24: Guidelines for quantitative 131I SPECT in dosimetry applications. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 54: 2182-8. PMID 24130233 DOI: 10.2967/Jnumed.113.122390  0.427
2013 Rong X, Frey EC. A collimator optimization method for quantitative imaging: application to Y-90 bremsstrahlung SPECT. Medical Physics. 40: 082504. PMID 23927349 DOI: 10.1118/1.4813297  0.641
2013 Hobbs RF, Wahl RL, Frey EC, Kasamon Y, Song H, Huang P, Jones RJ, Sgouros G. Radiobiologic optimization of combination radiopharmaceutical therapy applied to myeloablative treatment of non-Hodgkin lymphoma. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 54: 1535-42. PMID 23918734 DOI: 10.2967/Jnumed.112.117952  0.317
2013 Rong X, Ghaly M, Frey EC. Optimization of energy window for 90Y bremsstrahlung SPECT imaging for detection tasks using the ideal observer with model-mismatch. Medical Physics. 40: 062502. PMID 23718607 DOI: 10.1118/1.4805095  0.629
2013 Cheng L, Hobbs RF, Segars PW, Sgouros G, Frey EC. Improved dose-volume histogram estimates for radiopharmaceutical therapy by optimizing quantitative SPECT reconstruction parameters. Physics in Medicine and Biology. 58: 3631-47. PMID 23648371 DOI: 10.1088/0031-9155/58/11/3631  0.661
2013 Du Y, Madar I, Stumpf MJ, Rong X, Fung GS, Frey EC. Compensation for spill-in and spill-out partial volume effects in cardiac PET imaging. Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology. 20: 84-98. PMID 23151753 DOI: 10.1007/S12350-012-9649-Z  0.6
2013 Ghaly M, Links JM, Du Y, Frey EC. Model mismatch and the ideal observer in SPECT Proceedings of Spie - the International Society For Optical Engineering. 8673. DOI: 10.1117/12.2007529  0.365
2013 Lee TS, Bolch WE, Wayson MB, Treves ST, Sgouros G, Frey EC. Evaluation of image quality using Channelized Hotelling observer for pediatric diagnostic imaging of 99mTc-dimercaptosuccinic acid Ieee Nuclear Science Symposium Conference Record. DOI: 10.1109/NSSMIC.2013.6829167  0.352
2013 Lee TS, Feng T, Frey E, Tsui BMW. Task-based evaluation of motion compensated reconstructed images using 4D channelized Hotelling observer in dual gated SPECT Ieee Nuclear Science Symposium Conference Record. DOI: 10.1109/NSSMIC.2013.6829067  0.344
2012 Dewaraja YK, Frey EC, Sgouros G, Brill AB, Roberson P, Zanzonico PB, Ljungberg M. MIRD pamphlet No. 23: quantitative SPECT for patient-specific 3-dimensional dosimetry in internal radionuclide therapy. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 53: 1310-25. PMID 22743252 DOI: 10.2967/Jnumed.111.100123  0.357
2012 Rong X, Du Y, Frey EC. A method for energy window optimization for quantitative tasks that includes the effects of model-mismatch on bias: application to Y-90 bremsstrahlung SPECT imaging. Physics in Medicine and Biology. 57: 3711-25. PMID 22617760 DOI: 10.1088/0031-9155/57/12/3711  0.672
2012 Rong X, Du Y, Ljungberg M, Rault E, Vandenberghe S, Frey EC. Development and evaluation of an improved quantitative (90)Y bremsstrahlung SPECT method. Medical Physics. 39: 2346-58. PMID 22559605 DOI: 10.1118/1.3700174  0.637
2012 Frey EC, Humm JL, Ljungberg M. Accuracy and precision of radioactivity quantification in nuclear medicine images. Seminars in Nuclear Medicine. 42: 208-18. PMID 22475429 DOI: 10.1053/J.Semnuclmed.2011.11.003  0.477
2012 Wayson M, Lee C, Sgouros G, Treves ST, Frey E, Bolch WE. Internal photon and electron dosimetry of the newborn patient--a hybrid computational phantom study. Physics in Medicine and Biology. 57: 1433-57. PMID 22354044 DOI: 10.1088/0031-9155/57/5/1433  0.378
2012 Mok GSP, Ao ECI, Song N, Frey EC. The effect of non-rigid misregistration in sequential quantitative SPECT for targeted radionuclide therapy - A simulation study Ieee Nuclear Science Symposium Conference Record. 2938-2941. DOI: 10.1109/NSSMIC.2012.6551671  0.519
2011 Sgouros G, Frey EC, Bolch WE, Wayson MB, Abadia AF, Treves ST. An approach for balancing diagnostic image quality with cancer risk: application to pediatric diagnostic imaging of 99mTc-dimercaptosuccinic acid. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 52: 1923-9. PMID 22144506 DOI: 10.2967/Jnumed.111.092221  0.393
2011 Song N, Du Y, He B, Frey EC. Development and evaluation of a model-based downscatter compensation method for quantitative I-131 SPECT. Medical Physics. 38: 3193-204. PMID 21815394 DOI: 10.1118/1.3590382  0.649
2011 Song N, He B, Wahl RL, Frey EC. EQPlanar: a maximum-likelihood method for accurate organ activity estimation from whole body planar projections. Physics in Medicine and Biology. 56: 5503-24. PMID 21813961 DOI: 10.1088/0031-9155/56/17/004  0.565
2011 Wang X, Meier D, Taguchi K, Wagenaar DJ, Patt BE, Frey EC. Material separation in x-ray CT with energy resolved photon-counting detectors. Medical Physics. 38: 1534-46. PMID 21520865 DOI: 10.1117/12.877469  0.473
2011 Wang X, Meier D, Mikkelsen S, Maehlum GE, Wagenaar DJ, Tsui BM, Patt BE, Frey EC. MicroCT with energy-resolved photon-counting detectors. Physics in Medicine and Biology. 56: 2791-816. PMID 21464527 DOI: 10.1088/0031-9155/56/9/011  0.517
2011 Taguchi K, Zhang M, Frey EC, Wang X, Iwanczyk JS, Nygard E, Hartsough NE, Tsui BM, Barber WC. Modeling the performance of a photon counting x-ray detector for CT: energy response and pulse pileup effects. Medical Physics. 38: 1089-102. PMID 21452746 DOI: 10.1118/1.3539602  0.504
2011 He X, Cheng L, Fessler JA, Frey EC. Regularized image reconstruction algorithms for dual-isotope myocardial perfusion SPECT (MPS) imaging using a cross-tracer prior. Ieee Transactions On Medical Imaging. 30: 1169-83. PMID 20952334 DOI: 10.1109/Tmi.2010.2087031  0.66
2011 Frey E. WE-E-214-01: Targeted Radionuclide Therapy Medical Physics. 38: 3821-3821. DOI: 10.1118/1.3613390  0.422
2010 Taguchi K, Frey EC, Wang X, Iwanczyk JS, Barber WC. An analytical model of the effects of pulse pileup on the energy spectrum recorded by energy resolved photon counting x-ray detectors. Medical Physics. 37: 3957-69. PMID 20879558 DOI: 10.1118/1.3429056  0.526
2010 Song N, He B, Frey EC. The effect of volume-of-interest misregistration on quantitative planar activity and dose estimation. Physics in Medicine and Biology. 55: 5483-97. PMID 20798459 DOI: 10.1088/0031-9155/55/18/014  0.605
2010 He X, Links JM, Frey EC. An investigation of the trade-off between the count level and image quality in myocardial perfusion SPECT using simulated images: the effects of statistical noise and object variability on defect detectability. Physics in Medicine and Biology. 55: 4949-61. PMID 20693615 DOI: 10.1088/0031-9155/55/17/005  0.405
2010 He B, Frey EC. The impact of 3D volume of interest definition on accuracy and precision of activity estimation in quantitative SPECT and planar processing methods. Physics in Medicine and Biology. 55: 3535-44. PMID 20508323 DOI: 10.1088/0031-9155/55/12/017  0.381
2010 He B, Frey EC. Effects of shortened acquisition time on accuracy and precision of quantitative estimates of organ activity. Medical Physics. 37: 1807-15. PMID 20443503 DOI: 10.1118/1.3358119  0.414
2010 Hobbs RF, Baechler S, Senthamizhchelvan S, Prideaux AR, Esaias CE, Reinhardt M, Frey EC, Loeb DM, Sgouros G. A gamma camera count rate saturation correction method for whole-body planar imaging. Physics in Medicine and Biology. 55: 817-31. PMID 20071766 DOI: 10.1088/0031-9155/55/3/018  0.411
2010 Wang X, Meier D, Oya P, Maehlum GE, Wagenaar DJ, Tsui BMW, Patt BE, Frey EC. Microcomputed tomography with a second generation photon-counting x-ray detector - Contrast analysis and material separation Progress in Biomedical Optics and Imaging - Proceedings of Spie. 7622. DOI: 10.1117/12.844301  0.553
2009 Segars WP, Lalush DS, Frey EC, Manocha D, King MA, Tsui BM. Improved Dynamic Cardiac Phantom Based on 4D NURBS and Tagged MRI. Ieee Transactions On Nuclear Science. 56: 2728-2738. PMID 20711514 DOI: 10.1109/Tns.2009.2016196  0.341
2009 Du Y, Frey EC. Quantitative evaluation of simultaneous reconstruction with model-based crosstalk compensation for 99mTc/123I dual-isotope simultaneous acquisition brain SPECT. Medical Physics. 36: 2021-33. PMID 19610291 DOI: 10.1118/1.3120411  0.51
2009 He B, Wahl RL, Sgouros G, Du Y, Jacene H, Kasecamp WR, Flinn I, Hammes RJ, Bianco J, Kahl B, Frey EC. Comparison of organ residence time estimation methods for radioimmunotherapy dosimetry and treatment planning--patient studies. Medical Physics. 36: 1595-601. PMID 19544775 DOI: 10.1118/1.3100265  0.442
2009 He B, Du Y, Segars WP, Wahl RL, Sgouros G, Jacene H, Frey EC. Evaluation of quantitative imaging methods for organ activity and residence time estimation using a population of phantoms having realistic variations in anatomy and uptake. Medical Physics. 36: 612-9. PMID 19292001 DOI: 10.1118/1.3063156  0.484
2009 Barber WC, Nygard E, Iwanczyk JS, Zhang M, Frey EC, Tsui BMW, Wessel JC, Malakhov N, Wawrzyniak G, Hartsough NE, Gandhi T, Taguchi K. Characterization of a novel photon counting detector for clinical CT: Count rate, energy resolution, and noise performance Progress in Biomedical Optics and Imaging - Proceedings of Spie. 7258. DOI: 10.1117/12.813915  0.395
2009 Wang X, Xu J, Taguchi K, Frey EC, Patt BE, Wagenaar DJ. Enhanced discrimination of calcified and soft arterial plaques using computed tomography with a multi-energy-Window photon counting X-ray detector Progress in Biomedical Optics and Imaging - Proceedings of Spie. 7258. DOI: 10.1117/12.813877  0.545
2009 Wang X, Meier D, Sundal BM, Oya P, Maehlum GE, Wagenaar DJ, Patt BE, Tsui BMW, Frey EC. A digital line-camera for energy resolved x-ray photon counting Ieee Nuclear Science Symposium Conference Record. 3453-3457. DOI: 10.1109/NSSMIC.2009.5401785  0.432
2008 He X, Song X, Frey EC. Application of three-class ROC analysis to task-based image quality assessment of simultaneous dual-isotope myocardial perfusion SPECT (MPS). Ieee Transactions On Medical Imaging. 27: 1556-67. PMID 18955172 DOI: 10.1109/TMI.2008.928921  0.328
2008 He X, Caffo BS, Frey EC. Toward realistic and practical ideal observer (IO) estimation for the optimization of medical imaging systems. Ieee Transactions On Medical Imaging. 27: 1535-43. PMID 18815105 DOI: 10.1109/Tmi.2008.924641  0.455
2008 Sgouros G, Frey E, Wahl R, He B, Prideaux A, Hobbs R. Three-dimensional imaging-based radiobiological dosimetry. Seminars in Nuclear Medicine. 38: 321-34. PMID 18662554 DOI: 10.1053/J.Semnuclmed.2008.05.008  0.447
2008 He B, Wahl RL, Du Y, Sgouros G, Jacene H, Flinn I, Frey EC. Comparison of residence time estimation methods for radioimmunotherapy dosimetry and treatment planning-Monte Carlo simulation studies Ieee Transactions On Medical Imaging. 27: 521-530. PMID 18390348 DOI: 10.1109/Tmi.2007.908131  0.45
2008 Wang X, He X, Taguchi K, Patt BE, Wagenaar DJ, Frey EC. Uniformity correction in photon-counting X-ray detector based on basis material decomposition Ieee Nuclear Science Symposium Conference Record. 4902-4905. DOI: 10.1109/NSSMIC.2008.4774338  0.52
2007 Du Y, Tsui BMW, Frey EC. Model-based crosstalk compensation for simultaneous Tc99m∕I123 dual-isotope brain SPECT imaging. Medical Physics. 34: 3530-3543. PMID 28524949 DOI: 10.1118/1.2768863  0.487
2007 Du Y, Tsui BM, Frey EC. Model-based crosstalk compensation for simultaneous 99mTc/123I dual-isotope brain SPECT imaging. Medical Physics. 34: 3530-43. PMID 17926956 DOI: 10.1118/1.2768863  0.391
2007 Xu J, Liu C, Wang Y, Frey EC, Tsui BM. Quantitative rotating multisegment slant-hole SPECT mammography with attenuation and collimator-detector response compensation. Ieee Transactions On Medical Imaging. 26: 906-16. PMID 17649904 DOI: 10.1109/Tmi.2007.895480  0.447
2007 Xu J, Frey EC, Taguchi K, Tsui BMW. A Poisson likelihood iterative reconstruction algorithm for material decomposition in CT Progress in Biomedical Optics and Imaging - Proceedings of Spie. 6510. DOI: 10.1117/12.713727  0.337
2007 Frey EC, Wang X, Du Y, Taguchi K, Xu J, Tsui BMW. Investigation of the use of photon counting X-ray detectors with energy discrimination capability for material decomposition in micro-computed tomography Progress in Biomedical Optics and Imaging - Proceedings of Spie. 6510. DOI: 10.1117/12.711711  0.302
2007 Frey EC, Taguchi K, Kapusta M, Xu J, Orskaug T, Ninive I, Wagenaar D, Patt B, Tsui BMW. MicroComputed tomography with a photon-counting X-ray detector Progress in Biomedical Optics and Imaging - Proceedings of Spie. 6510. DOI: 10.1117/12.711647  0.33
2007 He X, Caffo BS, Frey EC. Markov chain Monte Carlo (MCMC) based ideal observer estimation using a parameterized phantom and a pre-calculated dataset Progress in Biomedical Optics and Imaging - Proceedings of Spie. 6515. DOI: 10.1117/12.710173  0.372
2007 Du Y, Frey EC. Simultaneous 99mTc/201Tl/123i triple-isotope cardiac SPECT imaging Ieee Nuclear Science Symposium Conference Record. 6: 4213-4216. DOI: 10.1109/NSSMIC.2007.4437047  0.42
2007 Wang X, Xu J, Frey EC. Optimization of energy window widths in basis material decomposition using a multi-window photon counting X-ray detector Ieee Nuclear Science Symposium Conference Record. 5: 3826-3829. DOI: 10.1109/NSSMIC.2007.4436955  0.464
2007 Song N, He B, Frey EC. Investigation of effects of volume-of-interest mis-registration on accuracy of organ activity estimates obtained with quantitative planar processing Ieee Nuclear Science Symposium Conference Record. 4: 3105-3108. DOI: 10.1109/NSSMIC.2007.4436787  0.369
2007 Taguchi K, Segars WP, Kudo H, Frey EC, Fishman EK, Tsui BMW. Toward time resolved cardiac CT images with patient dose reduction: Image-based motion estimation Ieee Nuclear Science Symposium Conference Record. 4: 2029-2032. DOI: 10.1109/NSSMIC.2006.354312  0.312
2006 Xu J, Liu C, Wang YC, Frey EC, Tsui BM. Attenuation correction for rotating multi-segment slant-hole SPECT in breast imaging. Physica Medica : Pm : An International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (Aifb). 21: 44-7. PMID 17645993 DOI: 10.1016/S1120-1797(06)80023-2  0.444
2006 He B, Frey EC. Comparison of conventional, model-based quantitative planar, and quantitative SPECT image processing methods for organ activity estimation using In-111 agents. Physics in Medicine and Biology. 51: 3967-81. PMID 16885618 DOI: 10.1088/0031-9155/51/16/006  0.438
2006 He X, Links JM, Gilland KL, Tsui BM, Frey EC. Comparison of 180 degrees and 360 degrees acquisition for myocardial perfusion SPECT with compensation for attenuation, detector response, and scatter: Monte Carlo and mathematical observer results. Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology. 13: 345-53. PMID 16750779 DOI: 10.1016/J.Nuclcard.2006.03.008  0.382
2006 Du Y, Tsui BM, Frey EC. Model-based compensation for quantitative 123I brain SPECT imaging. Physics in Medicine and Biology. 51: 1269-82. PMID 16481693 DOI: 10.1088/0031-9155/51/5/016  0.532
2005 He B, Du Y, Song X, Segars WP, Frey EC. A Monte Carlo and physical phantom evaluation of quantitative In-111 SPECT. Physics in Medicine and Biology. 50: 4169-85. PMID 16177538 DOI: 10.1088/0031-9155/50/17/018  0.43
2005 Du Y, Tsui BM, Frey EC. Partial volume effect compensation for quantitative brain SPECT imaging. Ieee Transactions On Medical Imaging. 24: 969-76. PMID 16092329 DOI: 10.1109/Tmi.2005.850547  0.447
2005 Song X, Segars WP, Du Y, Tsui BMW, Frey EC. Fast modelling of the collimator-detector response in Monte Carlo simulation of SPECT imaging using the angular response function Physics in Medicine and Biology. 50: 1791-1804. PMID 15815096 DOI: 10.1088/0031-9155/50/8/011  0.464
2005 Segars WP, Mahesh M, Beck T, Frey EC, Tsui BMW. Validation of the 4D NCAT simulation tools for use in high-resolution x-ray CT research Progress in Biomedical Optics and Imaging - Proceedings of Spie. 5745: 828-834. DOI: 10.1117/12.595987  0.315
2005 Wang WT, Tsui BMW, Lalush DS, Tocharoenchai C, Frey EC. Optimization of acquisition parameters for simultaneous 201Tl and 99mTc dual-isotope myocardial imaging Ieee Transactions On Nuclear Science. 52: 1227-1235. DOI: 10.1109/Tns.2005.851421  0.473
2004 Qi Y, Tsui BMW, Gilland KL, Frey EC, Gullberg GT. Evaluation of parallel and fan-beam data acquisition geometries and strategies for myocardial SPECT imaging Ieee Transactions On Nuclear Science. 51: 667-672. DOI: 10.1109/Tns.2004.829737  0.452
2004 He X, Frey EC, Links JM, Gilland KL, Segars WP, Tsui BMW. A mathematical observer study for the evaluation and optimization of compensation methods for myocardial SPECT using a phantom population that realistically models patient variability Ieee Transactions On Nuclear Science. 51: 218-224. DOI: 10.1109/Tns.2004.823331  0.416
2004 Song X, Frey EC, Wang WT, Du Y, Tsui BMW. Validation and evaluation of model-based crosstalk compensation method in simultaneous 99mTc stress and 201Tl rest myocardial perfusion SPECT Ieee Transactions On Nuclear Science. 51: 72-79. DOI: 10.1109/TNS.2003.823017  0.345
2004 Stumpf MJ, Frey EC, Tsui BMW, Gullberg GT. An investigation of noise characteristics in OSEM reconstruction of fan beam SPECT using a rotating/warping projector/backprojector Ieee Nuclear Science Symposium Conference Record. 6: 3948-3952.  0.31
2004 Mok SP, Tsui BMW, Wang Y, Qi Y, Du Y, Segars WP, Yoder BC, Frey EC. Development and validation of a Monte Carlo simulation tool for multi-pinhole microSPECT Ieee Nuclear Science Symposium Conference Record. 6: 3440-3444.  0.3
2003 He X, Frey EC, Links JM, Song X, Tsui BMW. Comparison of penetration and scatter effects on defect contrast for GE and Siemens LEHR collimators in myocardial perfusion SPECT - A simulation study Ieee Nuclear Science Symposium Conference Record. 4: 2905-2909. DOI: 10.1109/TNS.2005.858224  0.331
2003 Narayanan MV, Pretorius PH, Dahlberg ST, Leppo JA, Botkin N, Krasnow J, Berndt W, Frey EC, King MA. Evaluation of Scatter Compensation Strategies and their Impact on Human Detection Performance Tc-99m Myocardial Perfusion Imaging Ieee Transactions On Nuclear Science. 50: 1522-1527. DOI: 10.1109/TNS.2003.817399  0.357
2003 Baird WH, Frey EC, Tsui BMW, Wang Y, Wessell DE. Evaluation of rotating slant-hole SPECT mammography using Monte Carlo Simulation methods Ieee Transactions On Nuclear Science. 50: 105-109. DOI: 10.1109/TNS.2002.807913  0.361
2003 Segars WP, Tsui BMW, Frey EC, Fishman EK. Extension of the 4D NCAT phantom to dynamic X-ray CT simulation Ieee Nuclear Science Symposium Conference Record. 5: 3195-3199.  0.327
2003 Song X, Frey EC, He X, Segars WP, Tsui BMW. A mathematical observer study for evaluation of a model-based compensation method for crosstalk in simultaneous dual isotope SPECT Ieee Nuclear Science Symposium Conference Record. 4: 2521-2525.  0.324
2003 Sawyer SA, Frey EC, He B, Wang Y, Tsui BMW. Implementation of short-scan reconstruction with compensation for geometric alignment for a micro-CT system Ieee Nuclear Science Symposium Conference Record. 4: 2981-2984.  0.321
2002 Frey EC, Gilland KL, Tsui BM. Application of task-based measures of image quality to optimization and evaluation of three-dimensional reconstruction-based compensation methods in myocardial perfusion SPECT. Ieee Transactions On Medical Imaging. 21: 1040-50. PMID 12564872 DOI: 10.1109/TMI.2002.804437  0.376
2002 de Jong HW, Wang WT, Frey EC, Viergever MA, Beekman FJ. Efficient simulation of SPECT down-scatter including photon interactions with crystal and lead. Medical Physics. 29: 550-60. PMID 11991127 DOI: 10.1118/1.1462638  0.321
2002 Du Y, Frey EC, Wang WT, Tsui BMW. Optimization of Acquisition Energy Windows in Simultaneous 99mTc/123I Brain SPECT Ieee Nuclear Science Symposium and Medical Imaging Conference. 2: 1018-1022. DOI: 10.1109/TNS.2003.817404  0.314
2002 Du Y, Frey EC, Wang WT, Tocharoenchai C, Baird WH, Tsui BMW. Combination of MCNP and SimSET for Monte Carlo simulation of SPECT with medium- and high-energy photons Ieee Transactions On Nuclear Science. 49: 668-674. DOI: 10.1109/TNS.2002.1039547  0.321
2002 Tsui BMW, Wang Y, Yoder BC, Frey EC. Micro-SPECT Proceedings - International Symposium On Biomedical Imaging. 2002: 373-376. DOI: 10.1109/ISBI.2002.1029271  0.339
2002 Wang WT, Frey EC, Tsui BMW, Tocharoenchai C. A model-based crosstalk compensation method for simultaneous TL-201 and TC-99M dual isotope myocardial SPECT imaging Ieee Nuclear Science Symposium and Medical Imaging Conference. 4: 2209-2213.  0.39
2002 Wang Y, Tsui BMW, Baird WH, Frey EC, Wessell DE. Investigation of acquisition and image reconstruction parameters for rotating multi-segment slant-hole SPECT Ieee Nuclear Science Symposium and Medical Imaging Conference. 4: 2143-2146.  0.358
2002 Qi YJ, Tsui BMW, Gilland KJ, Frey EC, Gullberg GT. Evaluation of data acquisition geometries and strategies for myocardial SPECT imaging Ieee Nuclear Science Symposium and Medical Imaging Conference. 4: 2161-2165.  0.331
2002 He X, Frey EC, Links J, Gilland KL, Segars WP, Tsui BMW. Evaluation and Optimization of Compensation Methods for Myocardial SPECT using a Set of Realistic Phantoms that Include Patient Variability Ieee Nuclear Science Symposium and Medical Imaging Conference. 2: 764-768.  0.305
2002 Narayanan MV, King MA, Pretorius PH, Dahlberg ST, Leppo JA, Botkin N, Krasnow J, Berndt W, Frey EC. Evaluation of Scatter Compensation Strategies and their Impact on Human Detection Performance in Tc-99m Myocardial Perfusion Imaging Ieee Nuclear Science Symposium and Medical Imaging Conference. 3: 1524-1528.  0.337
2001 Baird WH, Frey EC, Tsui BMW, Wang Y, Wessell DE. Evaluation of rotating slant-hole SPECT mammography using Monte-Carlo simulation methods Ieee Nuclear Science Symposium and Medical Imaging Conference. 3: 1331-1334.  0.324
2001 Du Y, Frey EC, Wang WT, Tocharoenchai C, Baird WH, Tsui BMW. Combination of MCNP and SimSET for Monte Carlo simulation of SPECT with medium and high energy photons Ieee Nuclear Science Symposium and Medical Imaging Conference. 3: 1358-1362.  0.321
2000 LaCroix KJ, Tsui BMW, Frey EC, Jaszczak RJ. Receiver operating characteristic evaluation of iterative reconstruction with attenuation correction in 99mTc-sestamibi myocardial SPECT images Journal of Nuclear Medicine. 41: 502-513. PMID 10716326  0.354
2000 Tsui BMW, Zhao XD, Sayeram S, Frey EC, Falen SW, McCartney WH. Evaluation of collimator-detector response compensation in tumor SPECT using medium- and high-energy collimators Ieee Nuclear Science Symposium and Medical Imaging Conference. 3: 18/1.  0.394
1999 Kadrmas DJ, Frey EC, Tsui BMW. Simultaneous technetium-99m/thallium-201 SPECT imaging with model-based compensation for cross-contaminating effects Physics in Medicine and Biology. 44: 1843-1860. PMID 10442716 DOI: 10.1088/0031-9155/44/7/319  0.709
1999 Wang WT, Tsui BMW, Frey EC, Wessell DE. Comparison of an analytical and an iterative based collimator-detector response compensation method in SPECT Ieee Nuclear Science Symposium and Medical Imaging Conference. 2: 1382-1386.  0.326
1999 Wollenweber SD, Tsui BMW, Lalush DS, Frey EC, McCartney WH, Tocharoenchai C, Rempel TD, Simcic V. Initial characterization of the Siemens E.CAM+: a dual-detector camera with coincidence imaging capability Ieee Nuclear Science Symposium and Medical Imaging Conference. 3: 1470-1476.  0.379
1998 Tsui BMW, Frey EC, LaCroix KJ, Lalush DS, McCartney WH, King MA, Gullberg GT. Quantitative myocardial perfusion SPECT Journal of Nuclear Cardiology. 5: 507-522. PMID 9796898 DOI: 10.1016/S1071-3581(98)90182-9  0.406
1998 Kadrmas DJ, Frey EC, Tsui BMW. Application of reconstruction-based scatter compensation to thallium-201 SPECT: Implementations for reduced reconstructed image noise Ieee Transactions On Medical Imaging. 17: 325-333. PMID 9735896 DOI: 10.1109/42.712122  0.709
1998 Kadrmas DJ, Frey EC, Karimi SS, Tsui BM. Fast implementations of reconstruction-based scatter compensation in fully 3D SPECT image reconstruction. Physics in Medicine and Biology. 43: 857-73. PMID 9572510 DOI: 10.1088/0031-9155/43/4/014  0.691
1997 Kadrmas DJ, Frey EC, Tsui BMW. Analysis of the reconstructibility and noise properties of scattered photons in 99mTc SPECT Physics in Medicine and Biology. 42: 2493-2516. PMID 9434303 DOI: 10.1088/0031-9155/42/12/014  0.686
1996 Kadrmas DJ, Frey EC, Tsui BM. An SVD Investigation of Modeling Scatter in Multiple Energy Windows for Improved SPECT Images. Ieee Transactions On Nuclear Science. 43: 2275-2284. PMID 20186285 DOI: 10.1109/23.531892  0.697
1996 Frey EC, Tsui BMW. New method for modeling the spatially-variant, object-dependent scatter response function in SPECT Ieee Nuclear Science Symposium &Amp; Medical Imaging Conference. 2: 1082-1086.  0.374
1996 Kadrmas DJ, Frey EC, Tsui BMW. Application of reconstruction-based scatter compensation to T1-201 SPECT Ieee Nuclear Science Symposium &Amp; Medical Imaging Conference. 3: 1663-1667.  0.381
1995 Li J, Tsui BMW, Welch A, Frey EC, Gullberg GT. Energy Window Optimization in Simultaneous Technetium-99m TCT and Thallium-201 SPECT Data Acquisition Ieee Transactions On Nuclear Science. 42: 1207-1213. DOI: 10.1109/23.467877  0.352
1994 Tsui BMW, Zhao X, Frey EC, McCartney WH. Quantitative single-photon emission computed tomography: Basic and clinical considerations Seminars in Nuclear Medicine. 24: 38-65. PMID 8122128 DOI: 10.1016/S0001-2998(05)80248-X  0.379
1994 Tsui BMW, Zhao XD, Gregoriou GK, Lalush DS, Frey EC, Johnston RE, McCartney WH. Quantitative Cardiac SPECT Reconstruction with Reduced Image Degradation Due to Patient Anatomy Ieee Transactions On Nuclear Science. 41: 2838-2844. DOI: 10.1109/23.340655  0.302
1993 Frey EC, Ju ZW, Tsui BMW. A Fast Projector-Backprojector Pair Modeling the Asymmtric, Spatially Varying Scatter Response Function for Scatter Compensation in SPECT Imaging Ieee Transactions On Nuclear Science. 40: 1192-1197. DOI: 10.1109/23.256735  0.303
1993 Tsui BMW, Zhao XD, Cao ZJ, Frey EC. Reconstruction Methods for Quantitative Brain SPECT Ieee Transactions On Nuclear Science. 40: 214-220. DOI: 10.1109/23.212344  0.324
1991 Tsui BMW, Gullberg GT, Zhao X, Frey EC. Comparison Between ML-EM and WLS-CG Algorithms for SPECT Image Reconstruction Ieee Transactions On Nuclear Science. 38: 1766-1772. DOI: 10.1109/23.124174  0.318
1990 Frey EC, Tsui BMW. Parameterization of the scatter response function in spect imaging using monte carlo simulation Ieee Transactions On Nuclear Science. 37: 1308-1315. DOI: 10.1109/23.57381  0.358
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