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Elizaveta S. Leshchiner, Ph.D. - Publications

Affiliations: 
2013 Chemistry and Chemical Biology Harvard University, Cambridge, MA, United States 
Area:
General Chemistry, Molecular Biology
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11 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Zou Y, Palte MJ, Deik AA, Li H, Eaton JK, Wang W, Tseng YY, Deasy R, Kost-Alimova M, Dančík V, Leshchiner ES, Viswanathan VS, Signoretti S, Choueiri TK, Boehm JS, et al. A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis. Nature Communications. 10: 1617. PMID 30962421 DOI: 10.1038/S41467-019-09277-9  0.384
2017 Leshchiner ES, Rush JS, Durney MA, Cao Z, Dančík V, Chittick B, Wu H, Petrone A, Bittker JA, Phillips A, Perez JR, Shamji AF, Kaushik VK, Daly MJ, Graham DB, et al. Small-molecule inhibitors directly target CARD9 and mimic its protective variant in inflammatory bowel disease. Proceedings of the National Academy of Sciences of the United States of America. 114: 11392-11397. PMID 29073062 DOI: 10.1073/Pnas.1705748114  0.351
2015 Cao Z, Conway KL, Heath RJ, Rush JS, Leshchiner ES, Ramirez-Ortiz ZG, Nedelsky NB, Huang H, Ng A, Gardet A, Cheng SC, Shamji AF, Rioux JD, Wijmenga C, Netea MG, et al. Ubiquitin Ligase TRIM62 Regulates CARD9-Mediated Anti-fungal Immunity and Intestinal Inflammation. Immunity. 43: 715-26. PMID 26488816 DOI: 10.1016/J.Immuni.2015.10.005  0.31
2015 Leshchiner ES, Parkhitko A, Bird GH, Luccarelli J, Bellairs JA, Escudero S, Opoku-Nsiah K, Godes M, Perrimon N, Walensky LD. Direct inhibition of oncogenic KRAS by hydrocarbon-stapled SOS1 helices. Proceedings of the National Academy of Sciences of the United States of America. 112: 1761-6. PMID 25624485 DOI: 10.1073/Pnas.1413185112  0.574
2014 Leshchiner ES, Bellairs J, Bird GH, Opoku-Nsiah K, Godes M, Walensky LD. Abstract B41: Direct inhibition of oncogenic KRAS by hydrocarbon-stapled SOS1 helices Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Rasonc14-B41  0.563
2014 Leshchiner E, Bellairs J, Bird GH, Opoku-Nsiah K, Godes M, Walensky LD. Abstract 2597: Direct inhibition of oncogenic KRAS by hydrocarbon-stapled SOS1 helices Cancer Research. 74: 2597-2597. DOI: 10.1158/1538-7445.Am2014-2597  0.479
2013 Hilgendorf KI, Leshchiner ES, Nedelcu S, Maynard MA, Calo E, Ianari A, Walensky LD, Lees JA. The retinoblastoma protein induces apoptosis directly at the mitochondria. Genes & Development. 27: 1003-15. PMID 23618872 DOI: 10.1101/Gad.211326.112  0.565
2013 Leshchiner ES, Braun CR, Bird GH, Walensky LD. Direct activation of full-length proapoptotic BAK. Proceedings of the National Academy of Sciences of the United States of America. 110: E986-95. PMID 23404709 DOI: 10.1073/Pnas.1214313110  0.553
2012 Gavathiotis E, Reyna DE, Bellairs JA, Leshchiner ES, Walensky LD. Direct and selective small-molecule activation of proapoptotic BAX. Nature Chemical Biology. 8: 639-45. PMID 22634637 DOI: 10.1038/Nchembio.995  0.565
2010 Mahon KP, Love KT, Whitehead KA, Qin J, Akinc A, Leshchiner E, Leshchiner I, Langer R, Anderson DG. Combinatorial approach to determine functional group effects on lipidoid-mediated siRNA delivery. Bioconjugate Chemistry. 21: 1448-54. PMID 20715849 DOI: 10.1021/Bc100041R  0.32
2009 Akinc A, Goldberg M, Qin J, Dorkin JR, Gamba-Vitalo C, Maier M, Jayaprakash KN, Jayaraman M, Rajeev KG, Manoharan M, Koteliansky V, Röhl I, Leshchiner ES, Langer R, Anderson DG. Development of lipidoid-siRNA formulations for systemic delivery to the liver. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 872-9. PMID 19259063 DOI: 10.1038/Mt.2009.36  0.308
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