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Fiona Crawford, PhD - Publications

Affiliations: 
Roskamp Institute University of South Florida, Tampa, FL, United States 
Website:
http://www.qub.ac.uk/sites/STEM/stem-careers/featured-people/?id=12

218 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Eisenbaum M, Pearson A, Ortiz C, Koprivica M, Cembran A, Mullan M, Crawford F, Ojo J, Bachmeier C. Repetitive head trauma and apoE4 induce chronic cerebrovascular alterations that impair tau elimination from the brain. Experimental Neurology. 374: 114702. PMID 38301863 DOI: 10.1016/j.expneurol.2024.114702  0.534
2023 Keegan AP, Stough C, Paris D, Luis CA, Abdullah L, Ait-Ghezala G, Chaykin J, Crawford F, Mullan M. Baseline serum brain-derived neurotrophic factor association with future cognition in community-dwelling older adults undergoing annual memory screening. Neurological Research. 1-8. PMID 38095353 DOI: 10.1080/01616412.2023.2294581  0.422
2023 Nkiliza A, Huguenard CJC, Aldrich GJ, Ferguson S, Cseresznye A, Darcey T, Evans JE, Dretsch M, Mullan M, Crawford F, Abdullah L. Levels of Arachidonic Acid-Derived Oxylipins and Anandamide Are Elevated Among Military ɛ4 Carriers With a History of Mild Traumatic Brain Injury and Post-Traumatic Stress Disorder Symptoms. Neurotrauma Reports. 4: 643-654. PMID 37786567 DOI: 10.1089/neur.2023.0045  0.454
2023 Eisenbaum M, Pearson A, Ortiz C, Mullan M, Crawford F, Ojo J, Bachmeier C. ApoE4 expression disrupts tau uptake, trafficking, and clearance in astrocytes. Glia. PMID 37668005 DOI: 10.1002/glia.24469  0.527
2023 McCartan R, Gratkowski A, Browning M, Hahn-Townsend C, Ferguson S, Morin A, Bachmeier C, Pearson A, Brown L, Mullan M, Crawford F, Tzekov R, Mouzon B. Human amnionic progenitor cell secretome mitigates the consequence of traumatic optic neuropathy in a mouse model. Molecular Therapy. Methods & Clinical Development. 29: 303-318. PMID 37359418 DOI: 10.1016/j.omtm.2023.04.002  0.415
2023 Pearson A, Ortiz C, Eisenbaum M, Arrate C, Browning M, Mullan M, Bachmeier C, Crawford F, Ojo JO. Deletion of PTEN in microglia ameliorates chronic neuroinflammation following repetitive mTBI. Molecular and Cellular Neurosciences. 103855. PMID 37084991 DOI: 10.1016/j.mcn.2023.103855  0.46
2023 Keegan AP, Stough C, Paris D, Luis CA, Abdullah L, Ait-Ghezala G, Crawford F, Mullan M. supplementation has no effect on serum brain-derived neurotrophic factor levels but beneficially modulates nuclear factor kappa B and cyclic AMP response element-binding protein levels in healthy elderly subjects. Journal of Clinical and Translational Research. 9: 50-58. PMID 37032999  0.441
2023 Huguenard CJC, Cseresznye A, Darcey T, Nkiliza A, Evans JE, Hazen SL, Mullan M, Crawford F, Abdullah L. Age and affect L-carnitine system metabolites in the brain in the APOE-TR model. Frontiers in Aging Neuroscience. 14: 1059017. PMID 36688151 DOI: 10.3389/fnagi.2022.1059017  0.481
2022 Huguenard CJC, Cseresznye A, Evans JE, Darcey T, Nkiliza A, Keegan AP, Luis C, Bennett DA, Arvanitakis Z, Yassine HN, Mullan M, Crawford F, Abdullah L. APOE ε4 and Alzheimer's disease diagnosis associated differences in L-carnitine, GBB, TMAO, and acylcarnitines in blood and brain. Current Research in Translational Medicine. 71: 103362. PMID 36436355 DOI: 10.1016/j.retram.2022.103362  0.539
2022 Ferguson S, McCartan R, Browning M, Hahn-Townsend C, Gratkowski A, Morin A, Abdullah L, Ait-Ghezala G, Ojo J, Sullivan K, Mullan M, Crawford F, Mouzon B. Impact of gulf war toxic exposures after mild traumatic brain injury. Acta Neuropathologica Communications. 10: 147. PMID 36258255 DOI: 10.1186/s40478-022-01449-x  0.455
2022 Morin A, Davis R, Darcey T, Mullan M, Mouzon B, Crawford F. Subacute and chronic proteomic and phosphoproteomic analyses of a mouse model of traumatic brain injury at two timepoints and comparison with chronic traumatic encephalopathy in human samples. Molecular Brain. 15: 62. PMID 35850691 DOI: 10.1186/s13041-022-00945-4  0.479
2022 Keegan AP, Joshi U, Abdullah L, Paris D, Darcey T, Niedospial D, Davis LA, Crawford F, Mullan M. Characterization of immune profile in an aging multiple sclerosis clinic population. Multiple Sclerosis and Related Disorders. 63: 103818. PMID 35523060 DOI: 10.1016/j.msard.2022.103818  0.367
2022 Menden A, Hall D, Hahn-Townsend C, Broedlow CA, Joshi U, Pearson A, Crawford F, Evans JE, Klatt N, Crynen S, Mullan M, Ait-Ghezala G. Exogenous lipase administration alters gut microbiota composition and ameliorates Alzheimer's disease-like pathology in APP/PS1 mice. Scientific Reports. 12: 4797. PMID 35314754 DOI: 10.1038/s41598-022-08840-7  0.548
2022 Oberlin S, Nkiliza A, Parks M, Evans JE, Klimas N, Keegan AP, Sullivan K, Krengel MH, Mullan M, Crawford F, Abdullah L. Sex-specific differences in plasma lipid profiles are associated with Gulf War Illness. Journal of Translational Medicine. 20: 73. PMID 35123492 DOI: 10.1186/s12967-022-03272-3  0.406
2021 Eisenbaum M, Pearson A, Gratkowski A, Mouzon B, Mullan M, Crawford F, Ojo J, Bachmeier C. Influence of traumatic brain injury on extracellular tau elimination at the blood-brain barrier. Fluids and Barriers of the Cns. 18: 48. PMID 34702292 DOI: 10.1186/s12987-021-00283-y  0.492
2021 Nkiliza A, Parks M, Cseresznye A, Oberlin S, Evans JE, Darcey T, Aenlle K, Niedospial D, Mullan M, Crawford F, Klimas N, Abdullah L. Sex-specific plasma lipid profiles of ME/CFS patients and their association with pain, fatigue, and cognitive symptoms. Journal of Translational Medicine. 19: 370. PMID 34454515 DOI: 10.1186/s12967-021-03035-6  0.398
2021 Ojo JO, Reed JM, Crynen G, Vallabhaneni P, Evans J, Shackleton B, Eisenbaum M, Ringland C, Edsell A, Mullan M, Crawford F, Bachmeier C. APOE genotype dependent molecular abnormalities in the cerebrovasculature of Alzheimer's disease and age-matched non-demented brains. Molecular Brain. 14: 110. PMID 34238312 DOI: 10.1186/s13041-021-00803-9  0.483
2021 Nkiliza A, Joshi U, Evans JE, Ait-Ghezala G, Parks M, Crawford F, Mullan M, Abdullah L. Adaptive Immune Responses Associated with the Central Nervous System Pathology of Gulf War Illness. Neuroscience Insights. 16: 26331055211018458. PMID 34104887 DOI: 10.1177/26331055211018458  0.399
2021 Ojo JO, Reed JM, Crynen G, Vallabhaneni P, Evans J, Shackleton B, Eisenbaum M, Ringland C, Edsell A, Mullan M, Crawford F, Bachmeier C. Molecular Pathobiology of the Cerebrovasculature in Aging and in Alzheimers Disease Cases With Cerebral Amyloid Angiopathy. Frontiers in Aging Neuroscience. 13: 658605. PMID 34079449 DOI: 10.3389/fnagi.2021.658605  0.527
2021 Ringland C, Schweig JE, Eisenbaum M, Paris D, Ait-Ghezala G, Mullan M, Crawford F, Abdullah L, Bachmeier C. MMP9 modulation improves specific neurobehavioral deficits in a mouse model of Alzheimer's disease. Bmc Neuroscience. 22: 39. PMID 34034683 DOI: 10.1186/s12868-021-00643-2  0.511
2021 Menden A, Crynen S, Mathura V, Paris D, Crawford F, Mullan M, Ait-Ghezala G. Novel, natural allosteric inhibitors and enhancers of Candida rugosa lipase activity. Bioorganic Chemistry. 109: 104732. PMID 33639364 DOI: 10.1016/j.bioorg.2021.104732  0.389
2020 Ojo J, Eisenbaum M, Shackleton B, Lynch C, Joshi U, Saltiel N, Pearson A, Ringland C, Paris D, Mouzon B, Mullan M, Crawford F, Bachmeier C. Mural cell dysfunction leads to altered cerebrovascular tau uptake following repetitive head trauma. Neurobiology of Disease. 105237. PMID 33383188 DOI: 10.1016/j.nbd.2020.105237  0.511
2020 Morin A, Mouzon B, Ferguson S, Paris D, Browning M, Stewart W, Mullan M, Crawford F. Nilvadipine suppresses inflammation via inhibition of P-SYK and restores spatial memory deficits in a mouse model of repetitive mild TBI. Acta Neuropathologica Communications. 8: 166. PMID 33076989 DOI: 10.1186/s40478-020-01045-x  0.31
2020 Pearson A, Ajoy R, Crynen G, Reed JM, Algamal M, Mullan M, Purohit D, Crawford F, Ojo JO. Molecular abnormalities in autopsied brain tissue from the inferior horn of the lateral ventricles of nonagenarians and Alzheimer disease patients. Bmc Neurology. 20: 317. PMID 32854643 DOI: 10.1186/S12883-020-01849-3  0.551
2020 Menden A, Hall D, Broedlow CA, Darcey T, Crawford F, Klatt N, Crynen S, Mullan M, Ait-Ghezala G. Candida rugosa lipase alters the gastrointestinal environment in wild-type mice. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 130: 110579. PMID 32771891 DOI: 10.1016/J.Biopha.2020.110579  0.496
2020 Ringland C, Schweig JE, Paris D, Shackleton B, Lynch CE, Eisenbaum M, Mullan M, Crawford F, Abdullah L, Bachmeier C. Apolipoprotein E isoforms differentially regulate matrix metallopeptidase 9 function in Alzheimer's disease. Neurobiology of Aging. 95: 56-68. PMID 32758917 DOI: 10.1016/J.Neurobiolaging.2020.06.018  0.573
2020 Algamal M, Pearson AJ, Hahn-Townsend C, Burca I, Mullan M, Crawford F, Ojo JO. Repeated unpredictable stress and social isolation induce chronic HPA axis dysfunction and persistent abnormal fear memory. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 110035. PMID 32682873 DOI: 10.1016/J.Pnpbp.2020.110035  0.476
2020 Dyer AH, Murphy C, Briggs R, Lawlor B, Kennelly SP, Lawlor B, Segurado R, Kennelly S, Marcel GM, Howard R, Pasquier F, Borjesson-Hanson A, Tsolaki M, Lucca U, ... ... Crawford F, et al. Antidepressant Use and Orthostatic Hypotension in Older Adults Living with Mild-to-Moderate Alzheimer Disease. International Journal of Geriatric Psychiatry. PMID 32668020 DOI: 10.1002/gps.5377  0.511
2020 Joshi U, Evans JE, Pearson A, Saltiel N, Cseresznye A, Darcey T, Ojo J, Keegan AP, Oberlin S, Mouzon B, Paris D, Klimas N, Sullivan K, Mullan M, Crawford F, et al. Targeting sirtuin activity with nicotinamide riboside reduces neuroinflammation in a GWI mouse model. Neurotoxicology. PMID 32343995 DOI: 10.1016/J.Neuro.2020.04.006  0.525
2020 Schweig JE, Yao H, Jin C, Crawford F, Mullan M, Paris D. Neuronal Spleen tyrosine kinase (SYK) mediates cytokine release in Transgenic Tau P301S mice organotypic brain slice cultures. Neuroscience Letters. 134992. PMID 32334108 DOI: 10.1016/J.Neulet.2020.134992  0.585
2020 Ojo JO, Crynen G, Algamal M, Vallabhaneni P, Leary P, Mouzon B, Reed JM, Mullan M, Crawford F. Unbiased Proteomic Approach Identifies Pathobiological Profiles in the Brains of Preclinical Models of Repetitive Mild Traumatic Brain Injury, Tauopathy, and Amyloidosis. Asn Neuro. 12: 1759091420914768. PMID 32241177 DOI: 10.1177/1759091420914768  0.578
2020 Abdullah L, Crawford F, Tsolaki M, Börjesson-Hanson A, Olde Rikkert M, Pasquier F, Wallin A, Kennelly S, Ait-Ghezala G, Paris D, Hendrix S, Blennow K, Lawlor B, Mullan M. The Influence of Baseline Alzheimer's Disease Severity on Cognitive Decline and CSF Biomarkers in the NILVAD Trial. Frontiers in Neurology. 11: 149. PMID 32210906 DOI: 10.3389/Fneur.2020.00149  0.591
2020 Huguenard CJC, Cseresznye A, Evans JE, Oberlin S, Langlois H, Ferguson S, Darcey T, Nkiliza A, Dretsch M, Mullan M, Crawford F, Abdullah L. Plasma Lipidomic Analyses in Cohorts With mTBI and/or PTSD Reveal Lipids Differentially Associated With Diagnosis and ε4 Carrier Status. Frontiers in Physiology. 11: 12. PMID 32082186 DOI: 10.3389/Fphys.2020.00012  0.501
2020 Emmerich T, Abdullah L, Ojo J, Mouzon B, Nguyen T, Crynen G, Evans JE, Reed J, Mullan M, Crawford F. Correction to: Mild TBI Results in a Long-Term Decrease in Circulating Phospholipids in a Mouse Model of Injury. Neuromolecular Medicine. PMID 32078110 DOI: 10.1007/S12017-020-08593-4  0.491
2019 Cui J, Reed J, Crynen G, Ait-Ghezala G, Crawford F, Shen Y, Li R. Proteomic Identification of Pathways Responsible for the Estradiol Therapeutic Window in AD Animal Models. Frontiers in Cellular Neuroscience. 13: 437. PMID 31680862 DOI: 10.3389/Fncel.2019.00437  0.407
2019 Yao H, Coppola K, Schweig JE, Crawford F, Mullan M, Paris D. Distinct Signaling Pathways Regulate TREM2 Phagocytic and NFκB Antagonistic Activities. Frontiers in Cellular Neuroscience. 13: 457. PMID 31649511 DOI: 10.3389/Fncel.2019.00457  0.535
2019 Menden A, Hall D, Paris D, Mathura V, Crawford F, Mullan M, Crynen S, Ait-Ghezala G. A fast, miniaturised assay developed for quantification of lipase enzyme activity. Journal of Enzyme Inhibition and Medicinal Chemistry. 34: 1474-1480. PMID 31414611 DOI: 10.1080/14756366.2019.1651312  0.448
2019 Joshi U, Evans JE, Joseph R, Emmerich T, Saltiel N, Lungmus C, Oberlin S, Langlois H, Ojo J, Mouzon B, Paris D, Mullan M, Jin C, Klimas N, Sullivan K, ... Crawford F, et al. Author Correction: Oleoylethanolamide treatment reduces neurobehavioral deficits and brain pathology in a mouse model of Gulf War Illness. Scientific Reports. 9: 11011. PMID 31337781 DOI: 10.1038/S41598-019-46255-Z  0.488
2019 Joshi U, Pearson A, Evans JE, Langlois H, Saltiel N, Ojo J, Klimas N, Sullivan K, Keegan AP, Oberlin S, Darcey T, Cseresznye A, Raya B, Paris D, Hammock B, ... ... Crawford F, et al. A permethrin metabolite is associated with adaptive immune responses in Gulf War Illness. Brain, Behavior, and Immunity. PMID 31325531 DOI: 10.1016/J.Bbi.2019.07.015  0.518
2019 Schweig JE, Yao H, Coppola K, Jin C, Crawford F, Mullan M, Paris D. Spleen tyrosine kinase (SYK) blocks autophagic Tau degradation and . The Journal of Biological Chemistry. PMID 31324720 DOI: 10.1074/Jbc.Ra119.008033  0.593
2019 Shackleton B, Ringland C, Abdullah L, Mullan M, Crawford F, Bachmeier C. Influence of Matrix Metallopeptidase 9 on Beta-Amyloid Elimination Across the Blood-Brain Barrier. Molecular Neurobiology. PMID 31209784 DOI: 10.1007/S12035-019-01672-Z  0.578
2019 Algamal M, Saltiel N, Pearson AJ, Ager B, Burca I, Mouzon BC, Diamond D, Mullan M, Ojo J, Crawford FC. Impact of repetitive mild traumatic brain injury on behavioral and hippocampal deficits in a mouse model of chronic stress. Journal of Neurotrauma. PMID 30963958 DOI: 10.1089/Neu.2018.6314  0.514
2019 Ojo JO, Algamal M, Leary P, Abdullah L, Mouzon B, Evans JE, Mullan M, Crawford F. Converging and Differential Brain Phospholipid Dysregulation in the Pathogenesis of Repetitive Mild Traumatic Brain Injury and Alzheimer's Disease. Frontiers in Neuroscience. 13: 103. PMID 30837829 DOI: 10.3389/Fnins.2019.00103  0.632
2019 Muza P, Bachmeier C, Mouzon B, Algamal M, Rafi NG, Lungmus C, Abdullah L, Evans JE, Ferguson S, Mullan M, Crawford F, Ojo JO. APOE Genotype Specific Effects on the Early Neurodegenerative Sequelae Following Chronic Repeated Mild Traumatic Brain Injury. Neuroscience. PMID 30711612 DOI: 10.1016/J.Neuroscience.2019.01.049  0.59
2019 Huguenard C, Cseresznye A, Evans J, Crawford F, Mullan M, Abdullah L. P2-251: Serum Acylcarnitine Lipids As Biomarkers Of Preclinical Alzheimer'S Disease Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.2658  0.542
2018 Ojo JO, Crynen G, Reed JM, Ajoy R, Vallabhaneni P, Algamal M, Leary P, Rafi NG, Mouzon B, Mullan M, Crawford F. Unbiased Proteomic Approach Identifies Unique and Coincidental Plasma Biomarkers in Repetitive mTBI and AD Pathogenesis. Frontiers in Aging Neuroscience. 10: 405. PMID 30618712 DOI: 10.3389/Fnagi.2018.00405  0.594
2018 Ojo JO, Algamal M, Leary P, Abdullah L, Mouzon B, Evans JE, Mullan M, Crawford F. Disruption in Brain Phospholipid Content in a Humanized Tau Transgenic Model Following Repetitive Mild Traumatic Brain Injury. Frontiers in Neuroscience. 12: 893. PMID 30564087 DOI: 10.3389/Fnins.2018.00893  0.562
2018 Ojo JO, Leary P, Lungmus C, Algamal M, Mouzon B, Bachmeier C, Mullan M, Stewart W, Crawford F. Subchronic Pathobiological Response Following Chronic Repetitive Mild Traumatic Brain Injury in an Aged Preclinical Model of Amyloid Pathogenesis. Journal of Neuropathology and Experimental Neurology. PMID 30395237 DOI: 10.1093/Jnen/Nly101  0.616
2018 Morin A, Mouzon B, Ferguson S, Paris D, Saltiel N, Lungmus C, Mullan M, Crawford F. Treatment With Nilvadipine Mitigates Inflammatory Pathology and Improves Spatial Memory in Aged hTau Mice After Repetitive Mild TBI. Frontiers in Aging Neuroscience. 10: 292. PMID 30364309 DOI: 10.3389/Fnagi.2018.00292  0.57
2018 Lawlor B, Segurado R, Kennelly S, Olde Rikkert MGM, Howard R, Pasquier F, Börjesson-Hanson A, Tsolaki M, Lucca U, Molloy DW, Coen R, Riepe MW, Kálmán J, Kenny RA, Cregg F, ... ... Crawford F, et al. Nilvadipine in mild to moderate Alzheimer disease: A randomised controlled trial. Plos Medicine. 15: e1002660. PMID 30248105 DOI: 10.1371/Journal.Pmed.1002660  0.568
2018 Joshi U, Evans JE, Joseph R, Emmerich T, Saltiel N, Lungmus C, Oberlin S, Langlois H, Ojo J, Mouzon B, Paris D, Mullan M, Jin C, Klimas N, Sullivan K, ... Crawford F, et al. Oleoylethanolamide treatment reduces neurobehavioral deficits and brain pathology in a mouse model of Gulf War Illness. Scientific Reports. 8: 12921. PMID 30150699 DOI: 10.1038/S41598-018-31242-7  0.536
2018 Algamal M, Ojo JO, Lungmus CP, Muza P, Cammarata C, Owens MJ, Mouzon BC, Diamond DM, Mullan M, Crawford F. Chronic Hippocampal Abnormalities and Blunted HPA Axis in an Animal Model of Repeated Unpredictable Stress. Frontiers in Behavioral Neuroscience. 12: 150. PMID 30079015 DOI: 10.3389/Fnbeh.2018.00150  0.505
2018 Mouzon BC, Bachmeier C, Ojo J, Acker C, Ferguson S, Crynen G, Davies P, Mullan M, Stewart W, Crawford FC. Chronic white matter degeneration, but no tau pathology at 1-year post-repetitive mild traumatic brain injury in tau transgenic model. Journal of Neurotrauma. PMID 29993324 DOI: 10.1089/Neu.2018.5720  0.495
2018 Mouzon B, Saltiel N, Ferguson S, Ojo J, Lungmus C, Lynch C, Algamal M, Morin A, Carper B, Bieler G, Mufson EJ, Stewart W, Mullan M, Crawford F. Impact of age on acute post-TBI neuropathology in mice expressing humanized tau: a Chronic Effects of Neurotrauma Consortium Study. Brain Injury. 1-10. PMID 29927671 DOI: 10.1080/02699052.2018.1486457  0.534
2018 Mouzon BC, Bachmeier C, Ojo JO, Acker CM, Ferguson S, Paris D, Ait-Ghezala G, Crynen G, Davies P, Mullan M, Stewart W, Crawford F. Lifelong behavioral and neuropathological consequences of repetitive mild traumatic brain injury. Annals of Clinical and Translational Neurology. 5: 64-80. PMID 29376093 DOI: 10.1002/Acn3.510  0.532
2017 Ferguson SA, Mouzon BC, Lynch C, Lungmus C, Morin A, Crynen G, Carper B, Bieler G, Mufson EJ, Stewart W, Mullan M, Crawford F. Negative Impact of Female Sex on Outcomes from Repetitive Mild Traumatic Brain Injury in hTau Mice Is Age Dependent: A Chronic Effects of Neurotrauma Consortium Study. Frontiers in Aging Neuroscience. 9: 416. PMID 29311903 DOI: 10.3389/Fnagi.2017.00416  0.544
2017 Schweig JE, Yao H, Beaulieu-Abdelahad D, Ait-Ghezala G, Mouzon B, Crawford F, Mullan M, Paris D. Alzheimer's disease pathological lesions activate the spleen tyrosine kinase. Acta Neuropathologica Communications. 5: 69. PMID 28877763 DOI: 10.1186/S40478-017-0472-2  0.601
2017 Keegan AP, Paris D, Luis CA, Abdullah L, Ait-Ghezala G, Beaulieu-Abdelahad D, Pryor M, Chaykin J, Crynen G, Crawford F, Mullan M. Plasma cytokine IL-6 levels and subjective cognitive decline: preliminary findings. International Journal of Geriatric Psychiatry. PMID 28639714 DOI: 10.1002/Gps.4752  0.528
2017 Do Carmo S, Crynen G, Paradis T, Reed J, Iulita MF, Ducatenzeiler A, Crawford F, Cuello AC. Hippocampal Proteomic Analysis Reveals Distinct Pathway Deregulation Profiles at Early and Late Stages in a Rat Model of Alzheimer's-Like Amyloid Pathology. Molecular Neurobiology. PMID 28502044 DOI: 10.1007/S12035-017-0580-9  0.4
2017 Emmerich T, Zakirova Z, Klimas N, Sullivan K, Shetty AK, Evans JE, Ait-Ghezala G, Laco GS, Hattiangady B, Shetty GA, Mullan M, Crynen G, Abdullah L, Crawford F. Phospholipid profiling of plasma from GW veterans and rodent models to identify potential biomarkers of Gulf War Illness. Plos One. 12: e0176634. PMID 28453542 DOI: 10.1371/Journal.Pone.0176634  0.507
2017 Zakirova Z, Reed J, Crynen G, Horne L, Hassan S, Mathura V, Mullan M, Crawford F, Ait-Ghezala G. Complementary proteomic approaches reveal mitochondrial dysfunction, immune and inflammatory dysregulation in a mouse model of gulf war illness. Proteomics. Clinical Applications. PMID 28371386 DOI: 10.1002/Prca.201600190  0.493
2017 Abdullah L, Evans JE, Emmerich T, Crynen G, Shackleton B, Keegan AP, Luis C, Tai L, LaDu MJ, Mullan M, Crawford F, Bachmeier C. APOE ε4 specific imbalance of arachidonic acid and docosahexaenoic acid in serum phospholipids identifies individuals with preclinical Mild Cognitive Impairment/Alzheimer's Disease. Aging. PMID 28333036 DOI: 10.18632/aging.101203  0.544
2017 Shackleton B, Crawford F, Bachmeier C. Apolipoprotein E-mediated modulation of ADAM10 in Alzheimer's disease. Current Alzheimer Research. PMID 28164773 DOI: 10.2174/1567205014666170203093219  0.4
2017 Crawford F. Neurodegenerative Pathobiology In Preclinical Models Of Repetitive Mild Traumatic Brain Injury Alzheimers & Dementia. 13: 171. DOI: 10.1016/J.Jalz.2017.07.010  0.315
2017 Ojo J, Algamal M, Abdullah L, Crawford F, Evans JE, Mullan M. Phospholipid Disruption In The Brain Links Mouse Models Of Repetitive Mild Traumatic Brain Injury And Alzheimer’S Disease Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.06.275  0.536
2017 Abdullah L, Evans JE, Shackleton B, Ojo J, Mullan M, Crawford F, Bachmeier C. Apoe-E4 Dependent Deficits In Dha Phospholipids And Transporters In Alzheimer’S Disease Patients With Severe Cerebral Amyloid Angiopathy Alzheimers & Dementia. 13: 1303. DOI: 10.1016/J.Jalz.2017.06.1986  0.542
2016 Abdullah L, Evans JE, Joshi U, Crynen G, Reed J, Mouzon B, Baumann S, Montague H, Zakirova Z, Emmerich T, Bachmeier C, Klimas N, Sullivan K, Mullan M, Ait-Ghezala G, ... Crawford F, et al. Long title: Translational potential of long-term decreases in mitochondrial lipids in a mouse model of Gulf War Illness. Toxicology. PMID 27984134 DOI: 10.1016/j.tox.2016.10.012  0.468
2016 Abdullah L, Evans JE, Joshi U, Crynen G, Reed J, Mouzon B, Baumann S, Montague H, Zakirova Z, Emmerich T, Bachmeier C, Klimas N, Sullivan K, Mullan M, Ait-Ghezala G, ... Crawford F, et al. Translational potential of long-term decreases in mitochondrial lipids in a mouse model of Gulf War Illness. Toxicology. 372: 22-33. PMID 27931520 DOI: 10.1016/J.Tox.2016.10.012  0.529
2016 Ferguson S, Mouzon BC, Paris D, Aponte D, Abdullah L, Stewart W, Mullan M, Crawford FC. Acute or delayed treatment with anatabine improves spatial memory and reduces pathological sequelae at chronic timepoints after repetitive mild TBI. Journal of Neurotrauma. PMID 27889957 DOI: 10.1089/Neu.2016.4636  0.531
2016 Tzekov R, Phifer J, Myers A, Mouzon B, Crawford F. Inflammatory changes in optic nerve after closed-head repeated traumatic brain injury: Preliminary study. Brain Injury. 30: 1428-1435. PMID 27834542 DOI: 10.1080/02699052.2016.1219062  0.347
2016 Lynch CE, Crynen G, Ferguson S, Mouzon B, Paris D, Ojo J, Leary P, Crawford F, Bachmeier C. Chronic cerebrovascular abnormalities in a mouse model of repetitive mild traumatic brain injury. Brain Injury. 30: 1414-1427. PMID 27834539 DOI: 10.1080/02699052.2016.1219060  0.313
2016 Mufson EJ, Perez SE, Nadeem M, Mahady L, Kanaan NM, Abrahamson EE, Ikonomovic MD, Crawford F, Alvarez V, Stein T, McKee AC. Progression of tau pathology within cholinergic nucleus basalis neurons in chronic traumatic encephalopathy: A chronic effects of neurotrauma consortium study. Brain Injury. 30: 1399-1413. PMID 27834536 DOI: 10.1080/02699052.2016.1219058  0.305
2016 Emmerich T, Abdullah L, Ojo J, Mouzon B, Nguyen T, Laco GS, Crynen G, Evans JE, Reed J, Mullan M, Crawford F. Mild TBI Results in a Long-Term Decrease in Circulating Phospholipids in a Mouse Model of Injury. Neuromolecular Medicine. PMID 27540748 DOI: 10.1007/S12017-016-8436-4  0.522
2016 Shackleton B, Crawford F, Bachmeier C. Inhibition of ADAM10 promotes the clearance of Aβ across the BBB by reducing LRP1 ectodomain shedding. Fluids and Barriers of the Cns. 13: 14. PMID 27503326 DOI: 10.1186/S12987-016-0038-X  0.413
2016 Meulenbroek O, O'Dwyer S, de Jong D, van Spijker G, Kennelly S, Cregg F, Olde Rikkert M, Abdullah L, Wallin A, Walsh C, Coen R, Kenny RA, Daly L, Segurado R, Borjesson-Hanson A, ... Crawford F, et al. European multicentre double-blind placebo-controlled trial of Nilvadipine in mild-to-moderate Alzheimer's disease-the substudy protocols: NILVAD frailty; NILVAD blood and genetic biomarkers; NILVAD cerebrospinal fluid biomarkers; NILVAD cerebral blood flow. Bmj Open. 6: e011584. PMID 27436668 DOI: 10.1136/bmjopen-2016-011584  0.475
2016 Ojo JO, Mouzon B, Algamal M, Leary P, Lynch C, Abdullah L, Evans J, Mullan M, Bachmeier C, Stewart W, Crawford F. Chronic Repetitive Mild Traumatic Brain Injury Results in Reduced Cerebral Blood Flow, Axonal Injury, Gliosis, and Increased T-Tau and Tau Oligomers. Journal of Neuropathology and Experimental Neurology. PMID 27251042 DOI: 10.1093/Jnen/Nlw035  0.564
2016 Tzekov R, Dawson C, Orlando M, Mouzon B, Reed J, Evans J, Crynen G, Mullan M, Crawford F. Sub-Chronic Neuropathological and Biochemical Changes in Mouse Visual System after Repetitive Mild Traumatic Brain Injury. Plos One. 11: e0153608. PMID 27088355 DOI: 10.1371/Journal.Pone.0153608  0.51
2016 Shackleton B, Crawford F, Bachmeier C. INHIBITION OF THE LRP1 SHEDDASES FACILITATES Aβ CLEARANCE ACROSS THE BBB Alzheimers & Dementia. 12: 465. DOI: 10.1016/J.Jalz.2016.06.911  0.346
2016 Lawlor B, O'Dwyer S, Cregg F, Meulenbroek O, Wallin A, Coen R, Anne KR, Rikkert MGMO, Kennelly S, Borjesson-Hanson A, Crawford F, Mullan M, Pasquier F, Molloy W, Tsolaki M, et al. Nilvad: An Investigator Driven Phase Iii Multi Centre European Clinical Trial Of Nilvadipine In Mild To Moderate Alzheimer'S Disease Alzheimers & Dementia. 12: 424. DOI: 10.1016/J.Jalz.2016.06.805  0.525
2016 Paris D, Schweig J, Beaulieu-Abdelahad D, Lin Y, Mullan M, Crawford F. Regulation Of Ab Production And Tau Phosphorylation Via Syk-Dependent Mechanisms Alzheimers & Dementia. 12: 1027. DOI: 10.1016/J.Jalz.2016.06.2122  0.475
2016 Abdullah L, Evans J, Shackleton B, Ojo J, Nguyen T, Reed J, Mullan M, Crawford F, Bachmeier C. Apoe4 Genotype-Dependent Deficits In Dha Containing Phospholipids And Dha Transporters In The Cerebrovasculature Of Alzheimer'S Disease Patients Alzheimers & Dementia. 12: 867. DOI: 10.1016/J.Jalz.2016.06.1782  0.551
2016 Schweig J, Beaulieu-Abdelahad D, Lin Y, Crawford F, Paris D, Mullan M. Abnormal Accumulation Of Activated Syk In Microglia And Dystrophic Neurites In Mouse Models Of Alzheimer’S Disease Alzheimers & Dementia. 12: 859. DOI: 10.1016/J.Jalz.2016.06.1763  0.532
2016 Abdullah L, Evans J, Emmerich T, Nguyen T, Crynen G, Shackleton B, Reed J, Keegan AP, Luis C, Tai L, LaDu MJ, Mullan M, Crawford F, Bachmeier C. Apoe4-Specific Imbalance In Arachidonic Acid And Docosahexaenoic Acid In Serum Phospholipids From Individuals With Preclinical Mci/Ad Alzheimers & Dementia. 12: 671. DOI: 10.1016/J.Jalz.2016.06.1519  0.52
2015 Emmerich T, Abdullah L, Crynen G, Dretsch M, Evans J, Ait-Ghenzala G, Reed J, Montague H, Chaytow H, Mathura V, Martin J, Pelot R, Ferguson S, Bishop A, Phillips J, ... ... Crawford FC, et al. Plasma lipidomic profiling in a military population of mTBI and PTSD with APOE ε4 dependent effect. Journal of Neurotrauma. PMID 26714394 DOI: 10.1089/Neu.2015.4061  0.503
2015 Ojo JO, Bachmeier C, Mouzon BC, Tzekov R, Mullan M, Davies H, Stewart MG, Crawford F. Ultrastructural Changes in the White and Gray Matter of Mice at Chronic Time Points After Repeated Concussive Head Injury. Journal of Neuropathology and Experimental Neurology. 74: 1012-35. PMID 26360375 DOI: 10.1097/Nen.0000000000000247  0.536
2015 Verma M, Beaulieu-Abdelahad D, Ait-Ghezala G, Li R, Crawford F, Mullan M, Paris D. Correction: Chronic Anatabine Treatment Reduces Alzheimer's Disease (AD)-Like Pathology and Improves Socio-Behavioral Deficits in a Transgenic Mouse Model of AD. Plos One. 10: e0134776. PMID 26230317 DOI: 10.1371/journal.pone.0134776  0.532
2015 Ojo JO, Mouzon BC, Crawford F. Repetitive head trauma, chronic traumatic encephalopathy and tau: Challenges in translating from mice to men. Experimental Neurology. PMID 26054886 DOI: 10.1016/J.Expneurol.2015.06.003  0.358
2015 Verma M, Beaulieu-Abdelahad D, Ait-Ghezala G, Li R, Crawford F, Mullan M, Paris D. Chronic Anatabine Treatment Reduces Alzheimer's Disease (AD)-Like Pathology and Improves Socio-Behavioral Deficits in a Transgenic Mouse Model of AD. Plos One. 10: e0128224. PMID 26010758 DOI: 10.1371/Journal.Pone.0128224  0.598
2015 Zakirova Z, Tweed M, Crynen G, Reed J, Abdullah L, Nissanka N, Mullan M, Mullan MJ, Mathura V, Crawford F, Ait-Ghezala G. Gulf War agent exposure causes impairment of long-term memory formation and neuropathological changes in a mouse model of Gulf War Illness. Plos One. 10: e0119579. PMID 25785457 DOI: 10.1371/Journal.Pone.0119579  0.5
2014 Paris D, Ait-Ghezala G, Bachmeier C, Laco G, Beaulieu-Abdelahad D, Lin Y, Jin C, Crawford F, Mullan M. The spleen tyrosine kinase (Syk) regulates Alzheimer amyloid-β production and Tau hyperphosphorylation. The Journal of Biological Chemistry. 289: 33927-44. PMID 25331948 DOI: 10.1074/Jbc.M114.608091  0.589
2014 Lawlor B, Kennelly S, O'Dwyer S, Cregg F, Walsh C, Coen R, Kenny RA, Howard R, Murphy C, Adams J, Daly L, Segurado R, Gaynor S, Crawford F, Mullan M, et al. NILVAD protocol: a European multicentre double-blind placebo-controlled trial of nilvadipine in mild-to-moderate Alzheimer's disease. Bmj Open. 4: e006364. PMID 25300460 DOI: 10.1136/bmjopen-2014-006364  0.495
2014 Abdullah L, Evans JE, Ferguson S, Mouzon B, Montague H, Reed J, Crynen G, Emmerich T, Crocker M, Pelot R, Mullan M, Crawford F. Lipidomic analyses identify injury-specific phospholipid changes 3 mo after traumatic brain injury. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 5311-21. PMID 25208845 DOI: 10.1096/Fj.14-258228  0.531
2014 Bachmeier C, Shackleton B, Ojo J, Paris D, Mullan M, Crawford F. Apolipoprotein E isoform-specific effects on lipoprotein receptor processing. Neuromolecular Medicine. 16: 686-96. PMID 25015123 DOI: 10.1007/S12017-014-8318-6  0.587
2014 Ojo JO, Greenberg MB, Leary P, Mouzon B, Bachmeier C, Mullan M, Diamond DM, Crawford F. Neurobehavioral, neuropathological and biochemical profiles in a novel mouse model of co-morbid post-traumatic stress disorder and mild traumatic brain injury. Frontiers in Behavioral Neuroscience. 8: 213. PMID 25002839 DOI: 10.3389/Fnbeh.2014.00213  0.505
2014 Tzekov R, Quezada A, Gautier M, Biggins D, Frances C, Mouzon B, Jamison J, Mullan M, Crawford F. Repetitive mild traumatic brain injury causes optic nerve and retinal damage in a mouse model. Journal of Neuropathology and Experimental Neurology. 73: 345-61. PMID 24607965 DOI: 10.1097/Nen.0000000000000059  0.494
2014 Mouzon BC, Bachmeier C, Ferro A, Ojo JO, Crynen G, Acker CM, Davies P, Mullan M, Stewart W, Crawford F. Chronic neuropathological and neurobehavioral changes in a repetitive mild traumatic brain injury model. Annals of Neurology. 75: 241-54. PMID 24243523 DOI: 10.1002/Ana.24064  0.538
2014 Ojo JO, Abdullah L, Evans J, Reed JM, Montague H, Mullan MJ, Crawford FC. Exposure to an organophosphate pesticide, individually or in combination with other Gulf War agents, impairs synaptic integrity and neuronal differentiation, and is accompanied by subtle microvascular injury in a mouse model of Gulf War agent exposure. Neuropathology : Official Journal of the Japanese Society of Neuropathology. 34: 109-27. PMID 24118348 DOI: 10.1111/neup.12061  0.451
2014 Paris D, Beaulieu-Abdelahad D, Ait-Ghezala G, Mathura V, Verma M, Roher AE, Reed J, Crawford F, Mullan M. Anatabine Attenuates Tau Phosphorylation and Oligomerization in P301S Tau Transgenic Mice Brain Disorders & Therapy. 3: 1-11. DOI: 10.4172/2168-975X.1000126  0.413
2014 Sheinerman K, Umansky S, Tsivinsky V, Keegan A, Abdullah L, Crawford F. Detection And Differentiation Of Mild Cognitive Impairment, Alzheimer'S And Parkinson’S Diseases By Analysis Of Brain-Enriched Micrornas In Plasma Alzheimers & Dementia. 10: 299. DOI: 10.1016/J.Jalz.2014.04.500  0.347
2013 Abdullah L, Evans JE, Montague H, Reed JM, Moser A, Crynen G, Gonzalez A, Zakirova Z, Ross I, Mullan C, Mullan M, Ait-Ghezala G, Crawford F. Chronic elevation of phosphocholine containing lipids in mice exposed to Gulf War agents pyridostigmine bromide and permethrin. Neurotoxicology and Teratology. 40: 74-84. PMID 24140745 DOI: 10.1016/J.Ntt.2013.10.002  0.524
2013 Paris D, Beaulieu-Abdelahad D, Mullan M, Ait-Ghezala G, Mathura V, Bachmeier C, Crawford F, Mullan MJ. Amelioration of experimental autoimmune encephalomyelitis by anatabine. Plos One. 8: e55392. PMID 23383175 DOI: 10.1371/Journal.Pone.0055392  0.504
2013 Ojo JO, Mouzon B, Greenberg MB, Bachmeier C, Mullan M, Crawford F. Repetitive mild traumatic brain injury augments tau pathology and glial activation in aged hTau mice. Journal of Neuropathology and Experimental Neurology. 72: 137-51. PMID 23334597 DOI: 10.1097/Nen.0B013E3182814Cdf  0.572
2013 Paris D, Beaulieu-Abdelahad D, Abdullah L, Bachmeier C, Ait-Ghezala G, Reed J, Verma M, Crawford F, Mullan M. Anti-inflammatory activity of anatabine via inhibition of STAT3 phosphorylation. European Journal of Pharmacology. 698: 145-53. PMID 23178521 DOI: 10.1016/J.Ejphar.2012.11.017  0.511
2013 Bachmeier C, Beaulieu-Abdelahad D, Crawford F, Mullan M, Paris D. Stimulation of the retinoid X receptor facilitates beta-amyloid clearance across the blood-brain barrier. Journal of Molecular Neuroscience : Mn. 49: 270-6. PMID 22890420 DOI: 10.1007/S12031-012-9866-6  0.585
2013 Bachmeier C, Paris D, Beaulieu-Abdelahad D, Mouzon B, Mullan M, Crawford F. A multifaceted role for apoE in the clearance of beta-amyloid across the blood-brain barrier. Neuro-Degenerative Diseases. 11: 13-21. PMID 22572854 DOI: 10.1159/000337231  0.614
2013 Pelot RC, Reed J, Crynen G, Evans J, Hart A, Plate T, Vallabhaneni P, Abdullah L, Mullan M, Crawford F. Rapid and cost-effective purification of Endo-Lys-N from maitake (Grifola frondosa) mushrooms for proteomics applications Current Proteomics. 10: 292-297. DOI: 10.2174/15701646113106660003  0.429
2013 Abdullah L, Evans J, Montague H, Gonzalez A, Shah A, Kirk B, Reed J, Crynen G, Pelot R, Keegan A, Luis C, Mullan M, Crawford F. Use of lipidomics to identify novel blood-based phospholipid biomarkers that distinguish between mild cognitive impairment and early Alzheimer's disease Alzheimers & Dementia. 9: 240. DOI: 10.1016/J.Jalz.2013.05.464  0.543
2013 Sheinerman K, Tsivinsky V, Crawford F, Mullan M, Abdullah L, Umansky S. Early detection of Alzheimer's disease by analysis of brain-enriched miRNA biomarkers in plasma Alzheimers & Dementia. 9: 236. DOI: 10.1016/J.Jalz.2013.05.450  0.498
2012 Sheinerman KS, Tsivinsky VG, Crawford F, Mullan MJ, Abdullah L, Umansky SR. Plasma microRNA biomarkers for detection of mild cognitive impairment. Aging. 4: 590-605. PMID 23001356  0.397
2012 Mouzon B, Chaytow H, Crynen G, Bachmeier C, Stewart J, Mullan M, Stewart W, Crawford F. Repetitive mild traumatic brain injury in a mouse model produces learning and memory deficits accompanied by histological changes. Journal of Neurotrauma. 29: 2761-73. PMID 22900595 DOI: 10.1089/Neu.2012.2498  0.46
2012 Abdullah L, Evans JE, Bishop A, Reed JM, Crynen G, Phillips J, Pelot R, Mullan MA, Ferro A, Mullan CM, Mullan MJ, Ait-Ghezala G, Crawford FC. Lipidomic profiling of phosphocholine-containing brain lipids in mice with sensorimotor deficits and anxiety-like features after exposure to Gulf War agents. Neuromolecular Medicine. 14: 349-61. PMID 22798222 DOI: 10.1007/s12017-012-8192-z  0.458
2012 Crawford F, Crynen G, Reed J, Mouzon B, Bishop A, Katz B, Ferguson S, Phillips J, Ganapathi V, Mathura V, Roses A, Mullan M. Identification of plasma biomarkers of TBI outcome using proteomic approaches in an APOE mouse model. Journal of Neurotrauma. 29: 246-60. PMID 21895520 DOI: 10.1089/Neu.2011.1789  0.53
2012 Kennelly S, Abdullah L, Kenny RA, Mathura V, Luis CA, Mouzon B, Crawford F, Mullan M, Lawlor B. Apolipoprotein E genotype-specific short-term cognitive benefits of treatment with the antihypertensive nilvadipine in Alzheimer's patients--an open-label trial. International Journal of Geriatric Psychiatry. 27: 415-22. PMID 21560164 DOI: 10.1002/Gps.2735  0.551
2011 Abdullah L, Crynen G, Reed J, Bishop A, Phillips J, Ferguson S, Mouzon B, Mullan M, Mathura V, Mullan M, Ait-Ghezala G, Crawford F. Proteomic CNS profile of delayed cognitive impairment in mice exposed to Gulf War agents. Neuromolecular Medicine. 13: 275-88. PMID 21986894 DOI: 10.1007/S12017-011-8160-Z  0.528
2011 Paris D, Beaulieu-Abdelahad D, Bachmeier C, Reed J, Ait-Ghezala G, Bishop A, Chao J, Mathura V, Crawford F, Mullan M. Anatabine lowers Alzheimer's Aβ production in vitro and in vivo. European Journal of Pharmacology. 670: 384-91. PMID 21958873 DOI: 10.1016/J.Ejphar.2011.09.019  0.58
2011 Kennelly SP, Abdullah L, Paris D, Parish J, Mathura V, Mullan M, Crawford F, Lawlor BA, Kenny RA. Demonstration of safety in Alzheimer's patients for intervention with an anti-hypertensive drug Nilvadipine: results from a 6-week open label study. International Journal of Geriatric Psychiatry. 26: 1038-45. PMID 21905098 DOI: 10.1002/Gps.2638  0.544
2011 Luis CA, Abdullah L, Ait-Ghezala G, Mouzon B, Keegan AP, Crawford F, Mullan M. Feasibility of Predicting MCI/AD Using Neuropsychological Tests and Serum β-Amyloid. International Journal of Alzheimer's Disease. 2011: 786264. PMID 21660215 DOI: 10.4061/2011/786264  0.546
2011 Paris D, Bachmeier C, Patel N, Quadros A, Volmar CH, Laporte V, Ganey J, Beaulieu-Abdelahad D, Ait-Ghezala G, Crawford F, Mullan MJ. Selective antihypertensive dihydropyridines lower Aβ accumulation by targeting both the production and the clearance of Aβ across the blood-brain barrier. Molecular Medicine (Cambridge, Mass.). 17: 149-62. PMID 21170472 DOI: 10.2119/Molmed.2010.00180  0.595
2011 Bakshi P, Margenthaler E, Reed J, Crawford F, Mullan M. Depletion of CXCR2 inhibits γ-secretase activity and amyloid-β production in a murine model of Alzheimer's disease. Cytokine. 53: 163-9. PMID 21084199 DOI: 10.1016/J.Cyto.2010.10.008  0.626
2011 Mullan M, Bachmeier C, Ait-Ghezala G, Beaulieu-Abdelahad D, Crawford F, Abdullah L, Kenny RA, Kennelly S, Lawlor B, Paris D. Mechanism of action of new Alzheimer's therapeutic in phase III clinical trials Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.09.124  0.498
2011 Lawlor B, Crawford F, Rikkert MO, Mullan M, Tsolaki M, Borjesson A, Pasquier F, Riepe M, Kenny RA, Howard R, Gaynor S, Molloy W. NILVAD: An investigator initiated multi-centre placebo-controlled phase III trial of Nilvadipine, a calcium channel blocker, in mild-to-moderate Alzheimer's disease Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.09.120  0.503
2011 Luis C, Abdullah L, Ait-Ghezala G, Keegan A, Ferguson S, Crawford F, Mullan M. A novel screening approach for MCI/AD Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.722  0.526
2011 Crawford F, Crynen G, Reed J, Katz B, Ducatenzeiler A, Mullan M, Cuello C. Proteomic characterization of a novel rat model of Alzheimer's disease Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.1447  0.541
2010 Ferguson S, Mouzon B, Kayihan G, Wood M, Poon F, Doore S, Mathura V, Humphrey J, O'Steen B, Hayes R, Roses A, Mullan M, Crawford F. Apolipoprotein E genotype and oxidative stress response to traumatic brain injury. Neuroscience. 168: 811-9. PMID 20105454 DOI: 10.1016/J.Neuroscience.2010.01.031  0.526
2010 Kayihan GC, Wood M, Mouzon B, Ferguson S, Margenthaler E, Mathura V, Mullan M, Crawford F. Gulf War agents trigger discrete transcriptional changes in human neuronal cells Toxicological and Environmental Chemistry. 92: 1783-1799. DOI: 10.1080/02772241003611946  0.479
2009 Abdullah L, Luis C, Paris D, Mouzon B, Ait-Ghezala G, Keegan AP, Wang D, Crawford F, Mullan M. Serum Abeta levels as predictors of conversion to mild cognitive impairment/Alzheimer disease in an ADAPT subcohort. Molecular Medicine (Cambridge, Mass.). 15: 432-7. PMID 19707525 DOI: 10.2119/Molmed.2009.00083  0.592
2009 Crawford F, Wood M, Ferguson S, Mathura V, Gupta P, Humphrey J, Mouzon B, Laporte V, Margenthaler E, O'Steen B, Hayes R, Roses A, Mullan M. Apolipoprotein E-genotype dependent hippocampal and cortical responses to traumatic brain injury. Neuroscience. 159: 1349-62. PMID 19409232 DOI: 10.1016/J.Neuroscience.2009.01.033  0.565
2009 Abdullah L, Luis C, Paris D, Ait-ghezala G, Mouzon B, Allen E, Parrish J, Mullan MA, Ferguson S, Wood M, Crawford F, Mullan M. High serum Abeta and vascular risk factors in first-degree relatives of Alzheimer's disease patients. Molecular Medicine (Cambridge, Mass.). 15: 95-100. PMID 19081767 DOI: 10.2119/Molmed.2008.00118  0.597
2009 Luis CA, Abdullah L, Paris D, Quadros A, Mullan M, Mouzon B, Ait-Ghezala G, Crawford F, Mullan M. Serum beta-amyloid correlates with neuropsychological impairment. Neuropsychology, Development, and Cognition. Section B, Aging, Neuropsychology and Cognition. 16: 203-18. PMID 18923961 DOI: 10.1080/13825580802411766  0.57
2009 Abdullah L, Reed J, Kayihan G, Mathura V, Mouzon B, Mullan M, Crawford F. Proteomic analysis of human neuronal cells treated with the gulf war agent pyridostigmine bromide Journal of Proteomics and Bioinformatics. 2: 439-444. DOI: 10.4172/Jpb.1000103  0.474
2008 Bakshi P, Margenthaler E, Laporte V, Crawford F, Mullan M. Novel role of CXCR2 in regulation of gamma-secretase activity. Acs Chemical Biology. 3: 777-89. PMID 19067586 DOI: 10.1021/Cb800167A  0.566
2008 Ait-ghezala G, Abdullah L, Volmar CH, Paris D, Luis CA, Quadros A, Mouzon B, Mullan MA, Keegan AP, Parrish J, Crawford FC, Mathura VS, Mullan MJ. Diagnostic utility of APOE, soluble CD40, CD40L, and Abeta1-40 levels in plasma in Alzheimer's disease. Cytokine. 44: 283-7. PMID 18835787 DOI: 10.1016/J.Cyto.2008.08.013  0.56
2007 Poon HF, Abdullah L, Reed J, Doore SM, Laird C, Mathura V, Mullan M, Crawford F. Improving image analysis in 2DGE-based redox proteomics by labeling protein carbonyl with fluorescent hydroxylamine. Biological Procedures Online. 9: 65-72. PMID 18385803 DOI: 10.1251/Bpo134  0.466
2007 Abdullah L, Paris D, Luis C, Quadros A, Parrish J, Valdes L, Keegan AP, Mathura V, Crawford F, Mullan M. The influence of diagnosis, intra- and inter-person variability on serum and plasma Abeta levels. Neuroscience Letters. 428: 53-8. PMID 17964720 DOI: 10.1016/J.Neulet.2007.09.058  0.565
2007 Crawford FC, Wood M, Ferguson S, Mathura VS, Faza B, Wilson S, Fan T, O'Steen B, Ait-Ghezala G, Hayes R, Mullan MJ. Genomic analysis of response to traumatic brain injury in a mouse model of Alzheimer's disease (APPsw). Brain Research. 1185: 45-58. PMID 17961517 DOI: 10.1016/j.brainres.2007.09.042  0.535
2007 Poon HF, Abdullah L, Mullan MA, Mullan MJ, Crawford FC. Cocaine-induced oxidative stress precedes cell death in human neuronal progenitor cells. Neurochemistry International. 50: 69-73. PMID 16956698 DOI: 10.1016/j.neuint.2006.06.012  0.374
2006 Borenstein AR, Mortimer JA, Wu Y, Jureidini-Webb FM, Fallin MD, Small BJ, Mullan M, Crawford FC. Apolipoprotein E and cognition in community-based samples of African Americans and Caucasians. Ethnicity & Disease. 16: 9-15. PMID 16599342  0.424
2006 Crawford FC, Wood ML, Wilson SE, Mathura VS, Hollen TR, Geall F, Kolippakkam DN, Mullan MJ. Cocaine induced inflammatory response in human neuronal progenitor cells. Journal of Neurochemistry. 97: 662-74. PMID 16539665 DOI: 10.1111/j.1471-4159.2006.03760.x  0.405
2006 Abdullah L, Ait-Ghezala G, Crawford F, Crowell TA, Barker WW, Duara R, Mullan M. The cyclooxygenase 2 -765 C promoter allele is a protective factor for Alzheimer's disease. Neuroscience Letters. 395: 240-3. PMID 16309832 DOI: 10.1016/J.Neulet.2005.10.090  0.574
2005 Ait-Ghezala G, Mathura VS, Laporte V, Quadros A, Paris D, Patel N, Volmar CH, Kolippakkam D, Crawford F, Mullan M. Genomic regulation after CD40 stimulation in microglia: relevance to Alzheimer's disease. Brain Research. Molecular Brain Research. 140: 73-85. PMID 16182406 DOI: 10.1016/J.Molbrainres.2005.07.014  0.601
2005 Patel NS, Paris D, Mathura V, Quadros AN, Crawford FC, Mullan MJ. Inflammatory cytokine levels correlate with amyloid load in transgenic mouse models of Alzheimer's disease. Journal of Neuroinflammation. 2: 9. PMID 15762998 DOI: 10.1186/1742-2094-2-9  0.499
2004 Paris D, Townsend K, Quadros A, Humphrey J, Sun J, Brem S, Wotoczek-Obadia M, DelleDonne A, Patel N, Obregon DF, Crescentini R, Abdullah L, Coppola D, Rojiani AM, Crawford F, et al. Inhibition of angiogenesis by Abeta peptides. Angiogenesis. 7: 75-85. PMID 15302999 DOI: 10.1023/B:Agen.0000037335.17717.Bf  0.521
2004 Todd Roach J, Volmar CH, Dwivedi S, Town T, Crescentini R, Crawford F, Tan J, Mullan M. Behavioral effects of CD40-CD40L pathway disruption in aged PSAPP mice. Brain Research. 1015: 161-8. PMID 15223380 DOI: 10.1016/J.Brainres.2004.05.004  0.577
2004 Paris D, Quadros A, Humphrey J, Patel N, Crescentini R, Crawford F, Mullan M. Nilvadipine antagonizes both Abeta vasoactivity in isolated arteries, and the reduced cerebral blood flow in APPsw transgenic mice. Brain Research. 999: 53-61. PMID 14746921 DOI: 10.1016/J.Brainres.2003.11.061  0.569
2003 Quadros A, Patel N, Crescentini R, Crawford F, Paris D, Mullan M. Increased TNFalpha production and Cox-2 activity in organotypic brain slice cultures from APPsw transgenic mice. Neuroscience Letters. 353: 66-8. PMID 14642439 DOI: 10.1016/J.Neulet.2003.08.076  0.577
2003 Paris D, Humphrey J, Quadros A, Patel N, Crescentini R, Crawford F, Mullan M. Vasoactive effects of A beta in isolated human cerebrovessels and in a transgenic mouse model of Alzheimer's disease: role of inflammation. Neurological Research. 25: 642-51. PMID 14503019 DOI: 10.1179/016164103101201940  0.596
2003 Crawford FC, Ait-Ghezala G, Morris M, Sutcliffe MJ, Hauser RA, Silver AA, Mullan MJ. Translocation breakpoint in two unrelated Tourette syndrome cases, within a region previously linked to the disorder. Human Genetics. 113: 154-61. PMID 12698358 DOI: 10.1007/s00439-003-0942-4  0.402
2003 Quadros A, Patel N, Crescentini R, Crawford F, Paris D, Mullan M. Increased TNFα production and Cox-2 activity in organotypic brain slice cultures from APPsw transgenic mice Neuroscience Letters. 353: 66-68. DOI: 10.1016/j.neulet.2003.08.076  0.448
2002 Tan J, Town T, Abdullah L, Wu Y, Placzek A, Small B, Kroeger J, Crawford F, Richards D, Mullan M. CD45 isoform alteration in CD4+ T cells as a potential diagnostic marker of Alzheimer's disease. Journal of Neuroimmunology. 132: 164-72. PMID 12417447 DOI: 10.1016/S0165-5728(02)00309-0  0.558
2002 Town T, Vendrame M, Patel A, Poetter D, DelleDonne A, Mori T, Smeed R, Crawford F, Klein T, Tan J, Mullan M. Reduced Th1 and enhanced Th2 immunity after immunization with Alzheimer's beta-amyloid(1-42). Journal of Neuroimmunology. 132: 49-59. PMID 12417433 DOI: 10.1016/S0165-5728(02)00307-7  0.546
2002 Tan J, Town T, Crawford F, Mori T, DelleDonne A, Crescentini R, Obregon D, Flavell RA, Mullan MJ. Role of CD40 ligand in amyloidosis in transgenic Alzheimer's mice. Nature Neuroscience. 5: 1288-93. PMID 12402041 DOI: 10.1038/Nn968  0.606
2002 Ait-Ghezala G, Abdullah L, Crescentini R, Crawford F, Town T, Singh S, Richards D, Duara R, Mullan M. Confirmation of association between D10S583 and Alzheimer's disease in a case--control sample. Neuroscience Letters. 325: 87-90. PMID 12044628 DOI: 10.1016/S0304-3940(02)00243-4  0.581
2002 Crawford FC, Vanderploeg RD, Freeman MJ, Singh S, Waisman M, Michaels L, Abdullah L, Warden D, Lipsky R, Salazar A, Mullan MJ. APOE genotype influences acquisition and recall following traumatic brain injury. Neurology. 58: 1115-8. PMID 11940706  0.46
2002 Tan J, Town T, Mori T, Obregon D, Wu Y, DelleDonne A, Rojiani A, Crawford F, Flavell RA, Mullan M. CD40 is expressed and functional on neuronal cells. The Embo Journal. 21: 643-52. PMID 11847112 DOI: 10.1093/Emboj/21.4.643  0.482
2002 Schinka JA, Town T, Abdullah L, Crawford FC, Ordorica PI, Francis E, Hughes P, Graves AB, Mortimer JA, Mullan M. A functional polymorphism within the mu-opioid receptor gene and risk for abuse of alcohol and other substances. Molecular Psychiatry. 7: 224-8. PMID 11840318 DOI: 10.1038/Sj.Mp.4000951  0.41
2001 Russ C, Powell JF, Zhao J, Baker M, Hutton M, Crawford F, Mullan M, Roks G, Cruts M, Lovestone S. The microtubule associated protein Tau gene and Alzheimer's disease--an association study and meta-analysis. Neuroscience Letters. 314: 92-6. PMID 11698154 DOI: 10.1016/S0304-3940(01)02289-3  0.679
2001 Mori T, Paris D, Town T, Rojiani AM, Sparks DL, Delledonne A, Crawford F, Abdullah LI, Humphrey JA, Dickson DW, Mullan MJ. Cholesterol accumulates in senile plaques of Alzheimer disease patients and in transgenic APP(SW) mice. Journal of Neuropathology and Experimental Neurology. 60: 778-85. PMID 11487052 DOI: 10.1093/Jnen/60.8.778  0.601
2001 Crawford FC, Freeman MJ, Schinka JA, Morris MD, Abdullah LI, Richards D, Sevush S, Duara R, Mullan MJ. Association between Alzheimer's disease and a functional polymorphism in the Myeloperoxidase gene. Experimental Neurology. 167: 456-9. PMID 11161635 DOI: 10.1006/exnr.2000.7560  0.531
2000 Tan J, Town T, Mori T, Wu Y, Saxe M, Crawford F, Mullan M. CD45 opposes beta-amyloid peptide-induced microglial activation via inhibition of p44/42 mitogen-activated protein kinase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 7587-94. PMID 11027218 DOI: 10.1523/Jneurosci.20-20-07587.2000  0.564
2000 Crawford FC, Freeman MJ, Schinka JA, Abdullah LI, Gold M, Hartman R, Krivian K, Morris MD, Richards D, Duara R, Anand R, Mullan MJ. A polymorphism in the cystatin C gene is a novel risk factor for late-onset Alzheimer's disease. Neurology. 55: 763-8. PMID 10993992  0.501
2000 Kuo YM, Crawford F, Mullan M, Kokjohn TA, Emmerling MR, Weller RO, Roher AE. Elevated A beta and apolipoprotein E in A betaPP transgenic mice and its relationship to amyloid accumulation in Alzheimer's disease. Molecular Medicine (Cambridge, Mass.). 6: 430-9. PMID 10952022 DOI: 10.1007/Bf03401785  0.58
2000 Sevush S, Peruyera G, Crawford F, Mullan M. Apolipoprotein-E epsilon 4 allele frequency and conferred risk for Cuban Americans with Alzheimer's disease. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 8: 254-6. PMID 10910426 DOI: 10.1097/00019442-200008000-00013  0.504
2000 Crawford FC, Freeman MJ, Schinka J, Abdullah LI, Richards D, Sevush S, Duara R, Mullan MJ. The genetic association between Cathepsin D and Alzheimer's disease. Neuroscience Letters. 289: 61-5. PMID 10899409 DOI: 10.1016/S0304-3940(00)01260-X  0.534
2000 Small BJ, Graves AB, McEvoy CL, Crawford FC, Mullan M, Mortimer JA. Is APOE--epsilon4 a risk factor for cognitive impairment in normal aging? Neurology. 54: 2082-8. PMID 10851367 DOI: 10.1212/WNL.54.11.2082  0.439
2000 Suo Z, Su G, Placzek A, Kundtz A, Humphrey J, Crawford F, Mullan M. A beta vasoactivity in vivo. Annals of the New York Academy of Sciences. 903: 156-63. PMID 10818502 DOI: 10.1111/J.1749-6632.2000.Tb06363.X  0.537
2000 Crawford F, Freeman M, Abdullah L, Schinka J, Gold M, Duara R, Mullan M. No association between the NOS3 codon 298 polymorphism and Alzheimer's disease in a sample from the United States. Annals of Neurology. 47: 687. PMID 10805350 DOI: 10.1002/1531-8249(200005)47:5<687::Aid-Ana30>3.0.Co;2-4  0.532
2000 Crawford F, Abdullah L, Schinka J, Suo Z, Gold M, Duara R, Mullan M. Gender-specific association of the angiotensin converting enzyme gene with Alzheimer's disease. Neuroscience Letters. 280: 215-9. PMID 10675799 DOI: 10.1016/S0304-3940(00)00791-6  0.582
2000 Morris M, Crawford F, Freeman MJ, Schinka J, Gold M, Duara R, Mullan M. Age and gender-specific effects of a myeloperoxidase promoter polymorphism in Alzheimer's disease Neurobiology of Aging. 21: 249. DOI: 10.1016/S0197-4580(00)83457-0  0.553
2000 Small BJ, Abdullah L, Freeman MJ, Crawford F, Duara R, Mullan M. Age and gender as risk modifiers of ApoE-ϵ4 in Alzheimer's disease Neurobiology of Aging. 21: 247. DOI: 10.1016/S0197-4580(00)83448-X  0.558
2000 Crawford F, Freeman MJ, Schinka J, Abdullah L, Gold M, Duara R, Mullan M. The cystatin C gene as a novel genetic risk factor for late onset Alzheimer's disease Neurobiology of Aging. 21: 204. DOI: 10.1016/S0197-4580(00)83247-9  0.534
2000 Mori T, Paris D, Crawford F, Mullan M. Histochemical detection of cholesterol in the senile plaques of transgenic APPSW mice Neurobiology of Aging. 21: 119. DOI: 10.1016/S0197-4580(00)82336-2  0.514
2000 Freeman MJ, Crawford F, Duara R, Gold M, Michael M. Ethnicity-dependent association of the cathepsin D C224T polymorphism with Alzheimer's disease Neurobiology of Aging. 21: 104. DOI: 10.1016/S0197-4580(00)82266-6  0.319
2000 Tan J, Town T, Paris D, Mori T, Crawford F, Mullan M. The CD40-CD40L interaction leads to microglial activation following β-amyloid stimulation Neurobiology of Aging. 21: 188. DOI: 10.1016/S0197-4580(00)82186-7  0.483
1999 Tan J, Town T, Paris D, Mori T, Suo Z, Crawford F, Mattson MP, Flavell RA, Mullan M. Microglial activation resulting from CD40-CD40L interaction after beta-amyloid stimulation. Science (New York, N.Y.). 286: 2352-5. PMID 10600748 DOI: 10.1126/Science.286.5448.2352  0.581
1999 Tan J, Town T, Suo Z, Wu Y, Song S, Kundtz A, Kroeger J, Humphrey J, Crawford F, Mullan M. Induction of CD40 on human endothelial cells by Alzheimer's beta-amyloid peptides. Brain Research Bulletin. 50: 143-8. PMID 10535333 DOI: 10.1016/S0361-9230(99)00122-7  0.522
1999 King DL, Arendash GW, Crawford F, Sterk T, Menendez J, Mullan MJ. Progressive and gender-dependent cognitive impairment in the APP(SW) transgenic mouse model for Alzheimer's disease. Behavioural Brain Research. 103: 145-62. PMID 10513583 DOI: 10.1016/S0166-4328(99)00037-6  0.546
1999 Town T, Paris D, Parker TA, Kundtz A, Tan J, Duara R, Gold M, Crawford F, Mullan M. Alzheimers disease is not associated with the hypertension genetic risk factors PLA(2) or G protein beta3, either independently or interactively with apolipoprotein E. American Journal of Medical Genetics. 88: 465-8. PMID 10490699 DOI: 10.1002/(Sici)1096-8628(19991015)88:5<465::Aid-Ajmg5>3.0.Co;2-M  0.586
1999 Town T, Abdullah L, Crawford F, Schinka J, Ordorica PI, Francis E, Hughes P, Duara R, Mullan M. Association of a functional mu-opioid receptor allele (+118A) with alcohol dependency. American Journal of Medical Genetics. 88: 458-61. PMID 10490697 DOI: 10.1002/(Sici)1096-8628(19991015)88:5<458::Aid-Ajmg3>3.0.Co;2-S  0.463
1999 Crawford F, Freeman M, Town T, Fallin D, Gold M, Duara R, Mullan M. No genetic association between polymorphisms in the Tau gene and Alzheimer's disease in clinic or population based samples. Neuroscience Letters. 266: 193-6. PMID 10465706 DOI: 10.1016/S0304-3940(99)00303-1  0.602
1999 Crawford F, Town T, Freeman M, Schinka J, Gold M, Duara R, Mullan M. The alpha-2 macroglobulin gene is not associated with Alzheimer's disease in a case-control sample. Neuroscience Letters. 270: 133-6. PMID 10462112 DOI: 10.1016/S0304-3940(99)00470-X  0.571
1999 Tan J, Town T, Paris D, Placzek A, Parker T, Crawford F, Yu H, Humphrey J, Mullan M. Activation of microglial cells by the CD40 pathway: relevance to multiple sclerosis. Journal of Neuroimmunology. 97: 77-85. PMID 10408982 DOI: 10.1016/S0165-5728(99)00053-3  0.47
1999 Arendash GW, Su GC, Crawford FC, Bjugstad KB, Mullan M. Intravascular beta-amyloid infusion increases blood pressure: implications for a vasoactive role of beta-amyloid in the pathogenesis of Alzheimer's disease. Neuroscience Letters. 268: 17-20. PMID 10400067 DOI: 10.1016/S0304-3940(99)00239-6  0.485
1999 Paris D, Town T, Parker TA, Tan J, Humphrey J, Crawford F, Mullan M. Inhibition of Alzheimer's beta-amyloid induced vasoactivity and proinflammatory response in microglia by a cGMP-dependent mechanism. Experimental Neurology. 157: 211-21. PMID 10222124 DOI: 10.1006/Exnr.1999.7055  0.598
1998 Suo Z, Humphrey J, Kundtz A, Sethi F, Placzek A, Crawford F, Mullan M. Soluble Alzheimers beta-amyloid constricts the cerebral vasculature in vivo. Neuroscience Letters. 257: 77-80. PMID 9865931 DOI: 10.1016/S0304-3940(98)00814-3  0.583
1998 Crawford F, Soto C, Suo Z, Fang C, Parker T, Sawar A, Frangione B, Mullan M. Alzheimer's beta-amyloid vasoactivity: identification of a novel beta-amyloid conformational intermediate. Febs Letters. 436: 445-8. PMID 9801166 DOI: 10.1016/S0014-5793(98)01170-3  0.504
1998 Suo Z, Tan J, Placzek A, Crawford F, Fang C, Mullan M. Alzheimer's beta-amyloid peptides induce inflammatory cascade in human vascular cells: the roles of cytokines and CD40. Brain Research. 807: 110-7. PMID 9757011 DOI: 10.1016/S0006-8993(98)00780-X  0.545
1998 Town T, Paris D, Fallin D, Duara R, Barker W, Gold M, Crawford F, Mullan M. The -491A/T apolipoprotein E promoter polymorphism association with Alzheimer's disease: independent risk and linkage disequilibrium with the known APOE polymorphism. Neuroscience Letters. 252: 95-8. PMID 9756330 DOI: 10.1016/S0304-3940(98)00567-9  0.53
1998 Crawford F, Fallin D, Suo Z, Abdullah L, Gold M, Gauntlett A, Duara R, Mullan M. The butyrylcholinesterase gene is neither independently nor synergistically associated with late-onset AD in clinic- and community-based populations. Neuroscience Letters. 249: 115-8. PMID 9682830 DOI: 10.1016/S0304-3940(98)00423-6  0.576
1998 Paris D, Parker TA, Town T, Suo Z, Fang C, Humphrey J, Crawford F, Mullan M. Role of peroxynitrite in the vasoactive and cytotoxic effects of Alzheimer's beta-amyloid1-40 peptide. Experimental Neurology. 152: 116-22. PMID 9682018 DOI: 10.1006/Exnr.1998.6828  0.589
1998 Crawford F, Suo Z, Fang C, Mullan M. Characteristics of the in vitro vasoactivity of beta-amyloid peptides. Experimental Neurology. 150: 159-68. PMID 9514824 DOI: 10.1006/Exnr.1997.6743  0.507
1997 Fallin D, Kundtz A, Town T, Gauntlett AC, Duara R, Barker W, Crawford F, Mullan M. No association between the low density lipoprotein receptor-related protein (LRP) gene and late-onset Alzheimer's disease in a community-based sample. Neuroscience Letters. 233: 145-7. PMID 9350853 DOI: 10.1016/S0304-3940(97)00634-4  0.593
1997 Crawford F, Suo Z, Fang C, Mullan M. beta-Amyloid peptides and enhancement of vasoconstriction by endothelin-1. Annals of the New York Academy of Sciences. 826: 461-2. PMID 9329724 DOI: 10.1111/J.1749-6632.1997.Tb48504.X  0.507
1997 Crawford F, Suo Z, Fang C, Sawar A, Su G, Arendash G, Mullan M. The vasoactivity of A beta peptides. Annals of the New York Academy of Sciences. 826: 35-46. PMID 9329679 DOI: 10.1111/J.1749-6632.1997.Tb48459.X  0.499
1997 Suo Z, Fang C, Crawford F, Mullan M. Superoxide free radical and intracellular calcium mediate A beta(1-42) induced endothelial toxicity. Brain Research. 762: 144-52. PMID 9262168 DOI: 10.1016/S0006-8993(97)00383-1  0.553
1997 Town T, Fallin D, Crawford F, Walsh S, Solomon R, Mullan M. Lack of association between the apolipoprotein E epsilon4 allele (APOE epsilon4) and chronic schizophrenia. American Journal of Medical Genetics. 74: 451-2. PMID 9259385 DOI: 10.1002/(Sici)1096-8628(19970725)74:4<451::Aid-Ajmg20>3.0.Co;2-G  0.475
1997 Cai X, Fallin D, Stanton J, Scibelli P, Duara R, Crawford F, Mullan M. APOE is linked to Alzheimer's disease in a large pedigree. American Journal of Medical Genetics. 74: 365-9. PMID 9259370 DOI: 10.1002/(Sici)1096-8628(19970725)74:4<365::Aid-Ajmg5>3.0.Co;2-O  0.607
1997 Fallin D, Gauntlett AC, Scibelli P, Cai X, Duara R, Gold M, Crawford F, Mullan M. No association between the very low density lipoprotein receptor gene and late-onset Alzheimer's disease nor interaction with the apolipoprotein E gene in population-based and clinic samples. Genetic Epidemiology. 14: 299-305. PMID 9181358 DOI: 10.1002/(Sici)1098-2272(1997)14:3<299::Aid-Gepi7>3.0.Co;2-0  0.565
1997 Cai X, Stanton J, Fallin D, Hoyne J, Duara R, Gold M, Sevush S, Scibelli P, Crawford F, Mullan M. No association between the intronic presenilin-1 polymorphism and Alzheimer's disease in clinic and population-based samples. American Journal of Medical Genetics. 74: 202-3. PMID 9129725 DOI: 10.1002/(Sici)1096-8628(19970418)74:2<202::Aid-Ajmg18>3.0.Co;2-M  0.578
1997 Fallin D, Reading S, Schinka J, Hoyne J, Scibelli P, Gold M, Crawford F, Mullan M. No interaction between the APOE and the alpha-1-antichymotrypsin genes on risk for Alzheimer's disease. American Journal of Medical Genetics. 74: 192-4. PMID 9129722 DOI: 10.1002/(Sici)1096-8628(19970418)74:2<192::Aid-Ajmg15>3.0.Co;2-D  0.592
1996 Mullan M, Scibelli P, Duara R, Fallin D, Gold M, Schinka J, Hoyne J, Osborne A, Sevush S, Crawford F. Familial and population-based studies of apolipoprotein E and Alzheimer's disease. Annals of the New York Academy of Sciences. 802: 16-26. PMID 8993480 DOI: 10.1111/J.1749-6632.1996.Tb32594.X  0.577
1996 Crawford F, Hoyne J, Cai X, Osborne A, Poston D, Zaglul J, Dajani N, Walsh S, Bradley R, Solomon R, Mullan M. Dopamine DRD2/Cys311 is not associated with chronic schizophrenia. American Journal of Medical Genetics. 67: 483-4. PMID 8886166 DOI: 10.1002/(Sici)1096-8628(19960920)67:5<483::Aid-Ajmg8>3.0.Co;2-L  0.459
1996 Crawford F, Scibelli P, Duara R, Barker B, Fallin D, Gold M, Hoyne J, Sevush S, Mullan M. 500 Familial and population based studies of APOE and APOCI in AD Neurobiology of Aging. 17. DOI: 10.1016/S0197-4580(96)80502-1  0.546
1995 Poduslo SE, Riggs D, Schwankhaus J, Osborne A, Crawford F, Mullan M. Association of apolipoprotein E but not B with Alzheimer's disease. Human Genetics. 96: 597-600. PMID 8530010 DOI: 10.1007/Bf00197418  0.561
1995 Crawford F, Hoyne J, Diaz P, Osborne A, Dorotheo J, Sheehan D, Mullan M. Occurrence of the Cys311 DRD2 variant in a pedigree multiply affected with panic disorder. American Journal of Medical Genetics. 60: 332-4. PMID 7485271 DOI: 10.1002/Ajmg.1320600414  0.47
1995 Bennett C, Crawford F, Osborne A, Diaz P, Hoyne J, Lopez R, Roques P, Duara R, Rossor M, Mullan M. Evidence that the APOE locus influences rate of disease progression in late onset familial Alzheimer's Disease but is not causative. American Journal of Medical Genetics. 60: 1-6. PMID 7485228 DOI: 10.1002/Ajmg.1320600102  0.573
1995 Crawford F, Goate A. Alzheimer's disease untangled. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 14: 727-34. PMID 1365885 DOI: 10.1002/Bies.950141102  0.565
1994 Mullan M, Crawford F, Buchanan J. Technical feasibility of genetic testing for Alzheimer's disease. Alzheimer Disease and Associated Disorders. 8: 102-15. PMID 8060603 DOI: 10.1097/00002093-199408020-00007  0.587
1994 Crawford F, Bennett C, Osborne A, Diaz P, Mullan M. Age of onset and genetic predisposition in familial Alzheimer's disease Neurobiology of Aging. 15. DOI: 10.1016/0197-4580(94)92980-7  0.543
1993 Houlden H, Crawford F, Rossor M, Mullan M. Screening for the APP codon 670/671 mutations in Alzheimer's disease. Neuroscience Letters. 154: 161-2. PMID 8395665 DOI: 10.1016/0304-3940(93)90196-R  0.565
1993 Mullan M, Houlden H, Crawford F, Kennedy A, Rogues P, Rossor M. Age of onset in familial early onset Alzheimer's disease correlates with genetic aetiology. American Journal of Medical Genetics. 48: 129-30. PMID 8291565 DOI: 10.1002/Ajmg.1320480303  0.533
1993 Mullan M, Crawford F. Genetic and molecular advances in Alzheimer's disease. Trends in Neurosciences. 16: 398-403. PMID 7504354 DOI: 10.1016/0166-2236(93)90007-9  0.573
1992 Crawford F, Chartier-Harlin MC, Mullan M, Hardy J, Delacourte A, Arnott G. Alzheimer's--a correction. Nature. 356: 390. PMID 1557118 DOI: 10.1038/356390B0  0.725
1992 Adroer R, Chartier-Harlin M, Crawford F, Oliva R. Improved direct sequencing of Alzheimer's amyloid precursor protein (APP) exons 16 and 17. Neuroscience Letters. 141: 69-71. PMID 1508403 DOI: 10.1016/0304-3940(92)90336-6  0.622
1992 Mullan M, Crawford F, Axelman K, Houlden H, Lilius L, Winblad B, Lannfelt L. A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid. Nature Genetics. 1: 345-7. PMID 1302033 DOI: 10.1038/Ng0892-345  0.573
1991 Chartier-Harlin MC, Crawford F, Houlden H, Warren A, Hughes D, Fidani L, Goate A, Rossor M, Roques P, Hardy J. Early-onset Alzheimer's disease caused by mutations at codon 717 of the beta-amyloid precursor protein gene. Nature. 353: 844-6. PMID 1944558 DOI: 10.1038/353844A0  0.799
1991 Chartier-Harlin MC, Crawford F, Hamandi K, Mullan M, Goate A, Hardy J, Backhovens H, Martin JJ, Broeckhoven CV. Screening for the beta-amyloid precursor protein mutation (APP717: Val----Ile) in extended pedigrees with early onset Alzheimer's disease. Neuroscience Letters. 129: 134-5. PMID 1922963 DOI: 10.1016/0304-3940(91)90738-F  0.768
1991 Crawford F, Hardy J, Mullan M, Goate A, Hughes D, Fidani L, Roques P, Rossor M, Chartier-Harlin MC. Sequencing of exons 16 and 17 of the beta-amyloid precursor protein gene in 14 families with early onset Alzheimer's disease fails to reveal mutations in the beta-amyloid sequence. Neuroscience Letters. 133: 1-2. PMID 1791986 DOI: 10.1016/0304-3940(91)90042-R  0.796
1991 Goate A, Chartier-Harlin MC, Mullan M, Brown J, Crawford F, Fidani L, Giuffra L, Haynes A, Irving N, James L. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature. 349: 704-6. PMID 1671712 DOI: 10.1038/349704A0  0.804
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