Year |
Citation |
Score |
2024 |
Nassour H, Pétrin D, Devost D, Billard E, Sleno R, Hébert TE, Chatenet D. Evidence for heterodimerization and functional interaction of the urotensin II and the angiotensin II type 1 receptors. Cellular Signalling. 116: 111056. PMID 38262555 DOI: 10.1016/j.cellsig.2024.111056 |
0.371 |
|
2023 |
Dallagnol JCC, Volkovich M, Chatenet D, Allen BG, Hébert TE. G Protein-Biased Agonists for Intracellular Angiotensin Receptors Promote Collagen Secretion in Myofibroblasts. Acs Chemical Biology. 18: 2050-2062. PMID 37611227 DOI: 10.1021/acschembio.3c00319 |
0.302 |
|
2023 |
Billard E, Hébert TE, Chatenet D. EXPLORATION OF THE UROCONTRIN A SCAFFOLD YIELDS NEW UROTENSINERGIC SYSTEM ALLOSTERIC MODULATOR AND COMPETITIVE ANTAGONISTS. Biochemical Pharmacology. 115485. PMID 36889446 DOI: 10.1016/j.bcp.2023.115485 |
0.306 |
|
2023 |
Khan SM, Martin RD, Bayne A, Pétrin D, Bourque K, Jones-Tabah J, Bouazza C, Blaney J, Lau J, Martins-Cannavino K, Gora S, Zhang A, MacKinnon S, Trieu P, Clarke PBS, et al. Gβγ subunits co-localize with RNA polymerase II and regulate transcription in cardiac fibroblasts. The Journal of Biological Chemistry. 103064. PMID 36841480 DOI: 10.1016/j.jbc.2023.103064 |
0.324 |
|
2022 |
Baidya M, Chaturvedi M, Dwivedi-Agnihotri H, Ranjan A, Devost D, Namkung Y, Stepniewski TM, Pandey S, Baruah M, Panigrahi B, Sarma P, Yadav MK, Maharana J, Banerjee R, Kawakami K, et al. Allosteric modulation of GPCR-induced β-arrestin trafficking and signaling by a synthetic intrabody. Nature Communications. 13: 4634. PMID 35941121 DOI: 10.1038/s41467-022-32386-x |
0.362 |
|
2022 |
Mazurara GR, Dallagnol JCC, Chatenet D, Allen BG, Hébert TE. The complicated lives of GPCRs in cardiac fibroblasts. American Journal of Physiology. Cell Physiology. PMID 35938678 DOI: 10.1152/ajpcell.00120.2022 |
0.399 |
|
2022 |
Jones-Tabah J, Mohammad H, Paulus EG, Clarke PBS, Hébert TE. The Signaling and Pharmacology of the Dopamine D1 Receptor. Frontiers in Cellular Neuroscience. 15: 806618. PMID 35110997 DOI: 10.3389/fncel.2021.806618 |
0.317 |
|
2021 |
Ferré S, Ciruela F, Dessauer CW, González-Maeso J, Hébert TE, Jockers R, Logothetis DE, Pardo L. G protein-coupled receptor-effector macromolecular membrane assemblies (GEMMAs). Pharmacology & Therapeutics. 107977. PMID 34480967 DOI: 10.1016/j.pharmthera.2021.107977 |
0.383 |
|
2021 |
Nassour H, Hoang TA, Martin RD, Dallagnol JCC, Billard É, Létourneau M, Novellino E, Carotenuto A, Allen BG, Tanny JC, Fournier A, Hébert TE, Chatenet D. Lipidated peptides derived from intracellular loops 2 and 3 of the urotensin II receptor act as biased allosteric ligands. The Journal of Biological Chemistry. 101057. PMID 34389356 DOI: 10.1016/j.jbc.2021.101057 |
0.351 |
|
2021 |
Tennakoon M, Senarath K, Kankanamge D, Ratnayake K, Wijayaratna D, Olupothage K, Ubeysinghe S, Martins-Cannavino K, Hébert TE, Karunarathne A. Subtype-dependent regulation of Gβγ signalling. Cellular Signalling. 82: 109947. PMID 33582184 DOI: 10.1016/j.cellsig.2021.109947 |
0.392 |
|
2020 |
Jones-Tabah J, Mohammad H, Hadj-Youssef S, Kim LEH, Martin RD, Benaliouad F, Tanny JC, Clarke PBS, Hébert TE. Dopamine D1 receptor signalling in dyskinetic Parkinsonian rats revealed by fiber photometry using FRET-based biosensors. Scientific Reports. 10: 14426. PMID 32879346 DOI: 10.1038/S41598-020-71121-8 |
0.423 |
|
2020 |
Lukasheva V, Devost D, Le Gouill C, Namkung Y, Martin RD, Longpré JM, Amraei M, Shinjo Y, Hogue M, Lagacé M, Breton B, Aoki J, Tanny JC, Laporte SA, Pineyro G, et al. Signal profiling of the βAR reveals coupling to novel signalling pathways and distinct phenotypic responses mediated by βAR and βAR. Scientific Reports. 10: 8779. PMID 32471984 DOI: 10.1038/S41598-020-65636-3 |
0.444 |
|
2020 |
Martin RD, Sun Y, MacKinnon S, Cuccia L, Pagé V, Hébert TE, Tanny JC. Differential activation of P-TEFb complexes in the development of cardiomyocyte hypertrophy following activation of distinct GPCRs. Molecular and Cellular Biology. PMID 32341082 DOI: 10.1128/Mcb.00048-20 |
0.433 |
|
2020 |
Bourque K, Jones-Tabah J, Devost D, Clarke PBS, Hébert TE. Exploring functional consequences of GPCR oligomerization requires a different lens. Progress in Molecular Biology and Translational Science. 169: 181-211. PMID 31952686 DOI: 10.1016/Bs.Pmbts.2019.11.001 |
0.491 |
|
2019 |
Omri S, Tahiri H, Pierre WC, Desjarlais M, Lahaie I, Loiselle SE, Rezende F, Lodygensky G, Hebert TE, Ong H, Chemtob S. Propranolol Attenuates Proangiogenic Activity of Mononuclear Phagocytes: Implication in Choroidal Neovascularization. Investigative Ophthalmology & Visual Science. 60: 4632-4642. PMID 31682714 DOI: 10.1167/Iovs.18-25502 |
0.413 |
|
2019 |
Lamine A, de Molliens MP, Létourneau M, Hébert TE, Vaudry D, Fournier A, Chatenet D. The amidated PACAP fragment is a potent reduced-size neuroprotective agent. Biochimica Et Biophysica Acta. General Subjects. PMID 31401178 DOI: 10.1016/J.Bbagen.2019.08.003 |
0.31 |
|
2019 |
de Molliens MP, Jamadagni P, Létourneau M, Devost D, Hébert TE, Patten SA, Fournier A, Chatenet D. Design and biological assessment of membrane-tethering neuroprotective peptides derived from the pituitary adenylate cyclase-activating polypeptide type 1 receptor. Biochimica Et Biophysica Acta. General Subjects. PMID 31306709 DOI: 10.1016/J.Bbagen.2019.07.007 |
0.475 |
|
2019 |
Bourque K, Devost D, Inoue A, Hébert TE. Combining Conformational Profiling of GPCRs with CRISPR/Cas9 Gene Editing Approaches. Methods in Molecular Biology (Clifton, N.J.). 1947: 169-182. PMID 30969416 DOI: 10.1007/978-1-4939-9121-1_9 |
0.457 |
|
2019 |
Fillion D, Devost D, Sleno R, Inoue A, Hébert TE. Asymmetric Recruitment of β-Arrestin1/2 by the Angiotensin II Type I and Prostaglandin F2α Receptor Dimer. Frontiers in Endocrinology. 10: 162. PMID 30936850 DOI: 10.3389/Fendo.2019.00162 |
0.446 |
|
2019 |
Fillion D, Devost D, Hébert TE. Measuring Recruitment of β-Arrestin to G Protein-Coupled Heterodimers Using Bioluminescence Resonance Energy Transfer. Methods in Molecular Biology (Clifton, N.J.). 1957: 83-91. PMID 30919348 DOI: 10.1007/978-1-4939-9158-7_5 |
0.427 |
|
2019 |
Sleno R, Hébert TE. Shaky ground - The nature of metastable GPCR signalling complexes. Neuropharmacology. PMID 30659839 DOI: 10.1016/J.Neuropharm.2019.01.018 |
0.46 |
|
2019 |
Martin R, Tanny J, Hebert T. SAT-037 Functional Interplay between Distinct P-TEFb Complexes Following Endothelin or α1-Adrenergic Receptor Activation in Rat Cardiomyocytes Journal of the Endocrine Society. 3. DOI: 10.1210/Js.2019-Sat-037 |
0.376 |
|
2019 |
Jones-Tabah J, Kim L, Clarke P, Hebert T. SAT-034 Photometry Based Measurement of G Protein-Coupled Receptor-Mediated Signalling Journal of the Endocrine Society. 3. DOI: 10.1210/Js.2019-Sat-034 |
0.464 |
|
2018 |
Namkung Y, LeGouill C, Kumar S, Cao Y, Teixeira LB, Lukasheva V, Giubilaro J, Simões SC, Longpré JM, Devost D, Hébert TE, Piñeyro G, Leduc R, Costa-Neto CM, Bouvier M, et al. Functional selectivity profiling of the angiotensin II type 1 receptor using pathway-wide BRET signaling sensors. Science Signaling. 11. PMID 30514808 DOI: 10.1126/Scisignal.Aat1631 |
0.504 |
|
2018 |
O'Brien SL, Johnstone EKM, Devost D, Conroy J, Reichelt ME, Purdue BW, Ayoub MA, Kawai T, Inoue A, Eguchi S, Hébert TE, Pfleger KDG, Thomas WG. BRET-based assay to monitor EGFR transactivation by the ATR reveals G protein-independent activation and ATR-EGFR complexes. Biochemical Pharmacology. PMID 30347205 DOI: 10.1016/J.Bcp.2018.10.017 |
0.349 |
|
2018 |
Billard E, Hébert TE, Chatenet D. Discovery of New Allosteric Modulators of the Urotensinergic System through Substitution of the Urotensin II-Related Peptide (URP) Phenylalanine Residue. Journal of Medicinal Chemistry. PMID 30183282 DOI: 10.1021/Acs.Jmedchem.8B00789 |
0.38 |
|
2018 |
de Molliens MP, Létourneau M, Devost D, Hébert TE, Fournier A, Chatenet D. New insights about the peculiar role of the 28-38 C-terminal segment and some selected residues in PACAP for signaling and neuroprotection. Biochemical Pharmacology. PMID 29704474 DOI: 10.1016/J.Bcp.2018.04.024 |
0.47 |
|
2018 |
Sleno R, Hébert TE. The Dynamics of GPCR Oligomerization and Their Functional Consequences. International Review of Cell and Molecular Biology. 338: 141-171. PMID 29699691 DOI: 10.1016/Bs.Ircmb.2018.02.005 |
0.464 |
|
2018 |
Martin RD, Sun Y, Bourque K, Audet N, Inoue A, Tanny JC, Hébert TE. Receptor- and cellular compartment-specific activation of the cAMP/PKA pathway by α1-adrenergic and ETA endothelin receptors. Cellular Signalling. PMID 29329779 DOI: 10.1016/J.Cellsig.2018.01.002 |
0.492 |
|
2017 |
Douchez A, Billard É, Hébert T, Chatenet D, Lubell WD. Design, synthesis and biological assessment of biased allosteric modulation of the urotensin II receptor using achiral 1,3,4-benzotriazepin-2-one turn mimics. Journal of Medicinal Chemistry. PMID 29131958 DOI: 10.1021/Acs.Jmedchem.7B01525 |
0.389 |
|
2017 |
Audet N, Dabouz R, Allen BG, Hébert TE. Nucleoligands- repurposing GPCR ligands to modulate nuclear-localized GPCRs in the cardiovascular system. Journal of Cardiovascular Pharmacology. PMID 28858907 DOI: 10.1097/Fjc.0000000000000535 |
0.461 |
|
2017 |
Billard E, Létourneau M, Hébert TE, Chatenet D. Insight into the role of Urotensin II-Related Peptide Tyrosine residue in UT activation. Biochemical Pharmacology. PMID 28784291 DOI: 10.1016/J.Bcp.2017.08.003 |
0.392 |
|
2017 |
Sleno R, Devost D, Pétrin D, Zhang A, Bourque K, Shinjo Y, Aoki J, Inoue A, Hébert TE. Conformational biosensors reveal allosteric interactions between heterodimeric AT1 angiotensin and prostaglandin F2α receptors. The Journal of Biological Chemistry. PMID 28584054 DOI: 10.1074/Jbc.M117.793877 |
0.486 |
|
2017 |
Bourque K, Pétrin D, Sleno R, Devost D, Zhang A, Hébert TE. Distinct Conformational Dynamics of Three G Protein-Coupled Receptors Measured Using FlAsH-BRET Biosensors. Frontiers in Endocrinology. 8: 61. PMID 28439254 DOI: 10.3389/Fendo.2017.00061 |
0.466 |
|
2017 |
Devost D, Sleno R, Petrin D, Zhang A, Shinjo Y, Okde R, Aoki J, Inoue A, Hebert TE. Conformational profiling of the AT1 angiotensin II receptor reflects biased agonism, G protein coupling and cellular context. The Journal of Biological Chemistry. PMID 28213525 DOI: 10.1074/Jbc.M116.763854 |
0.465 |
|
2016 |
Wargachuk R, Glazkova I, Audet N, Pétrin D, Trieu P, Hébert TE. VCP/p97 regulates β2AR quality control during receptor biosynthesis. Cellular Signalling. 30: 50-58. PMID 27887991 DOI: 10.1016/J.Cellsig.2016.11.015 |
0.462 |
|
2016 |
Jones-Tabah J, Clarke PB, Hébert TE. Measuring G protein-coupled receptor signalling in the brain with resonance energy transfer based biosensors. Current Opinion in Pharmacology. 32: 44-48. PMID 27837687 DOI: 10.1016/J.Coph.2016.10.008 |
0.47 |
|
2016 |
Machkalyan G, Trieu P, Pétrin D, Hébert TE, Miller GJ. Mass spectrometry analysis of PPIP5K1 interactions and data on cell motility of PPIP5K1-deficient cells. Data in Brief. 7: 1443-1446. PMID 27761507 DOI: 10.1016/J.Dib.2016.03.035 |
0.326 |
|
2016 |
Génier S, Degrandmaison J, Moreau P, Labrecque P, Hébert TE, Parent JL. Regulation of GPCR Expression through an interaction with CCT7, a subunit of the CCT/TRiC Complex. Molecular Biology of the Cell. PMID 27708139 DOI: 10.1091/Mbc.E16-04-0224 |
0.473 |
|
2016 |
Khan SM, Sung JY, Hebert TE. Gβγ ▯subunits - different spaces, different faces. Pharmacological Research. PMID 27378564 DOI: 10.1016/J.Phrs.2016.06.026 |
0.437 |
|
2016 |
Devost D, Audet N, Zhou C, Kobayashi H, Bonin H, Lukashova V, Le Gouill C, Bouvier M, Hébert TE. Cellular and subcellular context determine outputs from signaling biosensors. Methods in Cell Biology. 132: 319-37. PMID 26928550 DOI: 10.1016/Bs.Mcb.2015.11.010 |
0.424 |
|
2016 |
Wargachuk R, Devost D, Zhou C, Hébert TE. Tracking GPCR biosynthesis and degradation using a nonradioactive pulse chase methodology. Methods in Cell Biology. 132: 217-31. PMID 26928546 DOI: 10.1016/Bs.Mcb.2015.11.011 |
0.468 |
|
2016 |
Machkalyan G, Trieu P, Pétrin D, Hébert TE, Miller GJ. PPIP5K1 interacts with the exocyst complex through a C-terminal intrinsically disordered domain and regulates cell motility. Cellular Signalling. 28: 401-11. PMID 26854614 DOI: 10.1016/J.Cellsig.2016.02.002 |
0.369 |
|
2016 |
Hébert TE. Biasing the odds: Approaches to capturing, understanding and exploiting functional selectivity in GPCRs. Methods (San Diego, Calif.). 92: 1-4. PMID 26416495 DOI: 10.1016/J.Ymeth.2015.09.024 |
0.305 |
|
2016 |
Sleno R, Pétrin D, Devost D, Goupil E, Zhang A, Hébert TE. Designing BRET-based conformational biosensors for G protein-coupled receptors. Methods (San Diego, Calif.). 92: 11-8. PMID 25962643 DOI: 10.1016/J.Ymeth.2015.05.003 |
0.456 |
|
2015 |
Chidiac P, Hébert TE. GPCR Retreat 2014: a good view leads to many discoveries! Journal of Receptor and Signal Transduction Research. 35: 208-12. PMID 26366680 DOI: 10.3109/10799893.2015.1072977 |
0.357 |
|
2015 |
Robertson DN, Sleno R, Nagi K, Pétrin D, Hébert TE, Pineyro G. Design and construction of conformational biosensors to monitor ion channel activation: A prototype FlAsH/BRET-approach to Kir3 channels. Methods (San Diego, Calif.). PMID 26210401 DOI: 10.1016/J.Ymeth.2015.07.011 |
0.312 |
|
2015 |
Khan SM, Min A, Gora S, Houranieh GM, Campden R, Robitaille M, Trieu P, Pétrin D, Jacobi AM, Behlke MA, Angers S, Hébert TE. Gβ4γ1 as a modulator of M3 muscarinic receptor signalling and novel roles of Gβ1 subunits in the modulation of cellular signalling. Cellular Signalling. 27: 1597-608. PMID 25916507 DOI: 10.1016/J.Cellsig.2015.04.007 |
0.467 |
|
2015 |
Campden R, Audet N, Hébert TE. Nuclear G protein signaling: new tricks for old dogs. Journal of Cardiovascular Pharmacology. 65: 110-22. PMID 25590750 DOI: 10.1097/Fjc.0000000000000198 |
0.475 |
|
2015 |
Tadevosyan A, Létourneau M, Folch B, Doucet N, Villeneuve LR, Mamarbachi AM, Pétrin D, Hébert TE, Fournier A, Chatenet D, Allen BG, Nattel S. Photoreleasable ligands to study intracrine angiotensin II signalling. The Journal of Physiology. 593: 521-39. PMID 25433071 DOI: 10.1113/Jphysiol.2014.279109 |
0.379 |
|
2015 |
Vaniotis G, Gora S, Nantel A, Hébert TE, Allen BG. Examining the effects of nuclear GPCRs on gene expression using isolated nuclei. Methods in Molecular Biology (Clifton, N.J.). 1234: 185-95. PMID 25304357 DOI: 10.1007/978-1-4939-1755-6_15 |
0.753 |
|
2015 |
Campden R, Pétrin D, Robitaille M, Audet N, Gora S, Angers S, Hébert TE. Tandem affinity purification to identify cytosolic and nuclear gβγ-interacting proteins. Methods in Molecular Biology (Clifton, N.J.). 1234: 161-84. PMID 25304356 DOI: 10.1007/978-1-4939-1755-6_14 |
0.322 |
|
2014 |
Wang Y, Ho CC, Bang E, Rejon CA, Libasci V, Pertchenko P, Hébert TE, Bernard DJ. Bone morphogenetic protein 2 stimulates noncanonical SMAD2/3 signaling via the BMP type 1A receptor in gonadotrope-like cells: implications for FSH synthesis. Endocrinology. 155: 1970-81. PMID 24601881 DOI: 10.1210/En.2013-1741 |
0.423 |
|
2013 |
Goupil E, Laporte SA, Hébert TE. A simple method to detect allostery in GPCR dimers. Methods in Cell Biology. 117: 165-79. PMID 24143977 DOI: 10.1016/B978-0-12-408143-7.00009-8 |
0.441 |
|
2013 |
Rejon CA, Ho CC, Wang Y, Zhou X, Bernard DJ, Hébert TE. Cycloheximide inhibits follicle-stimulating hormone β subunit transcription by blocking de novo synthesis of the labile activin type II receptor in gonadotrope cells. Cellular Signalling. 25: 1403-12. PMID 23499904 DOI: 10.1016/J.Cellsig.2013.03.002 |
0.406 |
|
2013 |
Khan SM, Sleno R, Gora S, Zylbergold P, Laverdure JP, Labbé JC, Miller GJ, Hébert TE. The expanding roles of Gβγ subunits in G protein-coupled receptor signaling and drug action. Pharmacological Reviews. 65: 545-77. PMID 23406670 DOI: 10.1124/Pr.111.005603 |
0.376 |
|
2013 |
Zylbergold P, Sleno R, Hébert TE. A novel, radiolabel-free pulse chase strategy to study Kir3 channel ontogeny. Journal of Receptor and Signal Transduction Research. 33: 144-52. PMID 23368630 DOI: 10.3109/10799893.2013.764898 |
0.329 |
|
2013 |
Chidiac P, Hébert TE. GPCR Retreat 2012: timing is everything. Journal of Receptor and Signal Transduction Research. 33: 129-34. PMID 23351073 DOI: 10.3109/10799893.2012.759592 |
0.393 |
|
2013 |
Poursharifi P, Lapointe M, Pétrin D, Devost D, Gauvreau D, Hébert TE, Cianflone K. C5L2 and C5aR interaction in adipocytes and macrophages: insights into adipoimmunology. Cellular Signalling. 25: 910-8. PMID 23268185 DOI: 10.1016/J.Cellsig.2012.12.010 |
0.326 |
|
2013 |
Goupil E, Laporte SA, Hébert TE. GPCR heterodimers: asymmetries in ligand binding and signalling output offer new targets for drug discovery. British Journal of Pharmacology. 168: 1101-3. PMID 23121476 DOI: 10.1111/Bph.12040 |
0.46 |
|
2012 |
Pétrin D, Hébert TE. The functional size of GPCRs - monomers, dimers or tetramers? Sub-Cellular Biochemistry. 63: 67-81. PMID 23161133 DOI: 10.1007/978-94-007-4765-4_4 |
0.464 |
|
2012 |
Rebois RV, Maki K, Meeks JA, Fishman PH, Hébert TE, Northup JK. D2-like dopamine and β-adrenergic receptors form a signaling complex that integrates Gs- and Gi-mediated regulation of adenylyl cyclase. Cellular Signalling. 24: 2051-60. PMID 22759790 DOI: 10.1016/J.Cellsig.2012.06.011 |
0.459 |
|
2012 |
Goupil E, Laporte SA, Hebert TE. Functional Selectivity in GPCR Signaling: Understanding the Full Spectrum of Receptor Conformations Mini-Reviews in Medicinal Chemistry. 12: 817-830. PMID 22681252 DOI: 10.2174/138955712800959143 |
0.483 |
|
2012 |
Goupil E, Wisehart V, Khoury E, Zimmerman B, Jaffal S, Hébert TE, Laporte SA. Biasing the prostaglandin F2α receptor responses toward EGFR-dependent transactivation of MAPK. Molecular Endocrinology (Baltimore, Md.). 26: 1189-202. PMID 22638073 DOI: 10.1210/Me.2011-1245 |
0.487 |
|
2012 |
Ejendal KF, Dessauer CW, Hébert TE, Watts VJ. Dopamine D(2) Receptor-Mediated Heterologous Sensitization of AC5 Requires Signalosome Assembly. Journal of Signal Transduction. 2012: 210324. PMID 22523680 DOI: 10.1155/2012/210324 |
0.323 |
|
2012 |
Tadevosyan A, Vaniotis G, Allen BG, Hébert TE, Nattel S. G protein-coupled receptor signalling in the cardiac nuclear membrane: evidence and possible roles in physiological and pathophysiological function. The Journal of Physiology. 590: 1313-30. PMID 22183719 DOI: 10.1113/Jphysiol.2011.222794 |
0.809 |
|
2012 |
Wrzal PK, Goupil E, Laporte SA, Hébert TE, Zingg HH. Functional interactions between the oxytocin receptor and the β2-adrenergic receptor: implications for ERK1/2 activation in human myometrial cells. Cellular Signalling. 24: 333-41. PMID 21964067 DOI: 10.1016/J.Cellsig.2011.09.019 |
0.467 |
|
2012 |
Wrzal PK, Devost D, Pétrin D, Goupil E, Iorio-Morin C, Laporte SA, Zingg HH, Hébert TE. Allosteric interactions between the oxytocin receptor and the β2-adrenergic receptor in the modulation of ERK1/2 activation are mediated by heterodimerization. Cellular Signalling. 24: 342-50. PMID 21963428 DOI: 10.1016/J.Cellsig.2011.09.020 |
0.413 |
|
2012 |
Del Duca D, Tadevosyan A, Karbassi F, Akhavein F, Vaniotis G, Rodaros D, Villeneuve LR, Allen BG, Nattel S, Rohlicek CV, Hébert TE. Hypoxia in early life is associated with lasting changes in left ventricular structure and function at maturity in the rat. International Journal of Cardiology. 156: 165-73. PMID 21131074 DOI: 10.1016/J.Ijcard.2010.10.135 |
0.734 |
|
2012 |
Zylbergold P, Hébert TE. Kir3 channel signalling complexes in cardiac arrhythmias Drug Discovery Today: Disease Models. 9. DOI: 10.1016/J.Ddmod.2012.02.009 |
0.409 |
|
2011 |
Vaniotis G, Allen BG, Hébert TE. Nuclear GPCRs in cardiomyocytes: an insider's view of β-adrenergic receptor signaling. American Journal of Physiology. Heart and Circulatory Physiology. 301: H1754-64. PMID 21890692 DOI: 10.1152/Ajpheart.00657.2011 |
0.792 |
|
2011 |
Pétrin D, Robitaille M, Hébert TE. Real-time BRET assays to measure G protein/effector interactions. Methods in Molecular Biology (Clifton, N.J.). 756: 245-61. PMID 21870230 DOI: 10.1007/978-1-61779-160-4_13 |
0.33 |
|
2011 |
Pétrin D, Hébert TE. Imaging-based approaches to understanding g protein-coupled receptor signalling complexes. Methods in Molecular Biology (Clifton, N.J.). 756: 37-60. PMID 21870219 DOI: 10.1007/978-1-61779-160-4_2 |
0.455 |
|
2011 |
Glazkova I, Altosaar K, Hébert TE. Organizational complexity of β-adrenergic receptor signaling systems. Current Topics in Membranes. 67: 19-49. PMID 21771484 DOI: 10.1016/B978-0-12-384921-2.00002-1 |
0.502 |
|
2011 |
Vaniotis G, Del Duca D, Trieu P, Rohlicek CV, Hébert TE, Allen BG. Nuclear β-adrenergic receptors modulate gene expression in adult rat heart. Cellular Signalling. 23: 89-98. PMID 20732414 DOI: 10.1016/J.Cellsig.2010.08.007 |
0.791 |
|
2010 |
Zylbergold P, Ramakrishnan N, Hebert T. The role of G proteins in assembly and function of Kir3 inwardly rectifying potassium channels Channels (Austin, Tex.). 4: 411-421. PMID 20855978 DOI: 10.4161/Chan.4.5.13327 |
0.308 |
|
2010 |
Lamba P, Wang Y, Tran S, Ouspenskaia T, Libasci V, Hébert TE, Miller GJ, Bernard DJ. Activin A regulates porcine follicle-stimulating hormone beta-subunit transcription via cooperative actions of SMADs and FOXL2. Endocrinology. 151: 5456-67. PMID 20810560 DOI: 10.1210/En.2010-0605 |
0.307 |
|
2010 |
Hudson BD, Hébert TE, Kelly ME. Physical and functional interaction between CB1 cannabinoid receptors and beta2-adrenoceptors. British Journal of Pharmacology. 160: 627-42. PMID 20590567 DOI: 10.1111/J.1476-5381.2010.00681.X |
0.437 |
|
2010 |
Robitaille M, Gora S, Wang Y, Goupil E, Pétrin D, Del Duca D, Villeneuve LR, Allen BG, Laporte SA, Bernard DJ, Hébert TE. Gbetagamma is a negative regulator of AP-1 mediated transcription. Cellular Signalling. 22: 1254-66. PMID 20403427 DOI: 10.1016/J.Cellsig.2010.04.005 |
0.414 |
|
2010 |
Hudson BD, Hébert TE, Kelly ME. Ligand- and heterodimer-directed signaling of the CB(1) cannabinoid receptor. Molecular Pharmacology. 77: 1-9. PMID 19837905 DOI: 10.1124/Mol.109.060251 |
0.506 |
|
2010 |
Guan R, Wu X, Feng X, Zhang M, Hébert TE, Segaloff DL. Structural determinants underlying constitutive dimerization of unoccupied human follitropin receptors. Cellular Signalling. 22: 247-56. PMID 19800402 DOI: 10.1016/J.Cellsig.2009.09.023 |
0.383 |
|
2009 |
Robitaille M, Dupré DJ, Hébert TE. [The role of molecular chaperones in the assembly of heterotrimeric G proteins]. MéDecine Sciences : M/S. 25: 821-5. PMID 19849984 DOI: 10.1051/Medsci/20092510821 |
0.413 |
|
2009 |
Siso-Nadal F, Fox JJ, Laporte SA, Hébert TE, Swain PS. Cross-talk between signaling pathways can generate robust oscillations in calcium and cAMP. Plos One. 4: e7189. PMID 19844582 DOI: 10.1371/Journal.Pone.0007189 |
0.344 |
|
2009 |
Del Duca D, Wong G, Trieu P, Rodaros D, Kouremenos A, Tadevosyan A, Vaniotis G, Villeneuve LR, Tchervenkov CI, Nattel S, Allen BG, Hébert TE, Rohlicek CV. Association of neonatal hypoxia with lasting changes in left ventricular gene expression: an animal model. The Journal of Thoracic and Cardiovascular Surgery. 138: 538-46, 546.e1. PMID 19698832 DOI: 10.1016/J.Jtcvs.2009.04.042 |
0.735 |
|
2009 |
Zylbergold P, Hébert TE. A division of labor: asymmetric roles for GPCR subunits in receptor dimers. Nature Chemical Biology. 5: 608-9. PMID 19690532 DOI: 10.1038/Nchembio0909-608 |
0.475 |
|
2009 |
Zhang M, Feng X, Guan R, Hébert TE, Segaloff DL. A cell surface inactive mutant of the human lutropin receptor (hLHR) attenuates signaling of wild-type or constitutively active receptors via heterodimerization. Cellular Signalling. 21: 1663-71. PMID 19616090 DOI: 10.1016/J.Cellsig.2009.07.003 |
0.462 |
|
2009 |
Zhang X, Wang G, Dupré DJ, Feng Y, Robitaille M, Lazartigues E, Feng YH, Hébert TE, Wu G. Rab1 GTPase and dimerization in the cell surface expression of angiotensin II type 2 receptor. The Journal of Pharmacology and Experimental Therapeutics. 330: 109-17. PMID 19357319 DOI: 10.1124/Jpet.109.153460 |
0.403 |
|
2009 |
Duvernay MT, Dong C, Zhang X, Robitaille M, Hébert TE, Wu G. A single conserved leucine residue on the first intracellular loop regulates ER export of G protein-coupled receptors. Traffic (Copenhagen, Denmark). 10: 552-66. PMID 19220814 DOI: 10.1111/J.1600-0854.2009.00890.X |
0.42 |
|
2009 |
Guan R, Feng X, Wu X, Zhang M, Zhang X, Hébert TE, Segaloff DL. Bioluminescence resonance energy transfer studies reveal constitutive dimerization of the human lutropin receptor and a lack of correlation between receptor activation and the propensity for dimerization. The Journal of Biological Chemistry. 284: 7483-94. PMID 19147490 DOI: 10.1074/Jbc.M809150200 |
0.42 |
|
2009 |
Wang L, Dennis AT, Trieu P, Charron F, Ethier N, Hebert TE, Wan X, Ficker E. Intracellular potassium stabilizes human ether-Ã -go-go-related gene channels for export from endoplasmic reticulum. Molecular Pharmacology. 75: 927-37. PMID 19139152 DOI: 10.1124/Mol.108.053793 |
0.309 |
|
2009 |
Robitaille M, Ramakrishnan N, Baragli A, Hébert TE. Intracellular trafficking and assembly of specific Kir3 channel/G protein complexes. Cellular Signalling. 21: 488-501. PMID 19135528 DOI: 10.1016/J.Cellsig.2008.11.011 |
0.348 |
|
2009 |
Richer M, David M, Villeneuve LR, Trieu P, Ethier N, Pétrin D, Mamarbachi AM, Hébert TE. GABA-B(1) receptors are coupled to the ERK1/2 MAP kinase pathway in the absence of GABA-B(2) subunits. Journal of Molecular Neuroscience : Mn. 38: 67-79. PMID 19052921 DOI: 10.1007/S12031-008-9163-6 |
0.314 |
|
2009 |
Dupré DJ, Robitaille M, Rebois RV, Hébert TE. The role of Gbetagamma subunits in the organization, assembly, and function of GPCR signaling complexes. Annual Review of Pharmacology and Toxicology. 49: 31-56. PMID 18834311 DOI: 10.1146/Annurev-Pharmtox-061008-103038 |
0.48 |
|
2008 |
Rebois RV, Robitaille M, Pétrin D, Zylbergold P, Trieu P, Hébert TE. Combining protein complementation assays with resonance energy transfer to detect multipartner protein complexes in living cells. Methods (San Diego, Calif.). 45: 214-8. PMID 18586102 DOI: 10.1016/J.Ymeth.2008.06.006 |
0.3 |
|
2008 |
Hébert TE. Opioid and chemokine receptor heterodimers: arranged marriages or dangerous liaisons? The Biochemical Journal. 412: e7-9. PMID 18466114 DOI: 10.1042/BJ20080620 |
0.308 |
|
2008 |
Boivin B, Vaniotis G, Allen BG, Hébert TE. G protein-coupled receptors in and on the cell nucleus: a new signaling paradigm? Journal of Receptor and Signal Transduction Research. 28: 15-28. PMID 18437627 DOI: 10.1080/10799890801941889 |
0.792 |
|
2008 |
Baragli A, Grieco ML, Trieu P, Villeneuve LR, Hébert TE. Heterodimers of adenylyl cyclases 2 and 5 show enhanced functional responses in the presence of Galpha s. Cellular Signalling. 20: 480-92. PMID 18164588 DOI: 10.1016/J.Cellsig.2007.10.033 |
0.338 |
|
2007 |
Burstein B, Maguy A, Clément R, Gosselin H, Poulin F, Ethier N, Tardif JC, Hébert TE, Calderone A, Nattel S. Effects of resveratrol (trans-3,5,4'-trihydroxystilbene) treatment on cardiac remodeling following myocardial infarction. The Journal of Pharmacology and Experimental Therapeutics. 323: 916-23. PMID 17875610 DOI: 10.1124/Jpet.107.127548 |
0.306 |
|
2007 |
Hébert TE. Anti-beta1AR antibodies in dilated cardiomyopathy: are these a new class of receptor agonists? Cardiovascular Research. 76: 5-7. PMID 17707357 DOI: 10.1016/J.Cardiores.2007.07.011 |
0.436 |
|
2007 |
Dupré DJ, Robitaille M, Richer M, Ethier N, Mamarbachi AM, Hébert TE. Dopamine receptor-interacting protein 78 acts as a molecular chaperone for Ggamma subunits before assembly with Gbeta. The Journal of Biological Chemistry. 282: 13703-15. PMID 17363375 DOI: 10.1074/Jbc.M608846200 |
0.428 |
|
2007 |
Dupré DJ, Baragli A, Rebois RV, Ethier N, Hébert TE. Signalling complexes associated with adenylyl cyclase II are assembled during their biosynthesis. Cellular Signalling. 19: 481-9. PMID 16979872 DOI: 10.1016/J.Cellsig.2006.07.021 |
0.441 |
|
2006 |
Dupré DJ, Robitaille M, Ethier N, Villeneuve LR, Mamarbachi AM, Hébert TE. Seven transmembrane receptor core signaling complexes are assembled prior to plasma membrane trafficking. The Journal of Biological Chemistry. 281: 34561-73. PMID 16959776 DOI: 10.1074/Jbc.M605012200 |
0.497 |
|
2006 |
David M, Richer M, Mamarbachi AM, Villeneuve LR, Dupré DJ, Hebert TE. Interactions between GABA-B1 receptors and Kir 3 inwardly rectifying potassium channels. Cellular Signalling. 18: 2172-81. PMID 16809021 DOI: 10.1016/J.Cellsig.2006.05.014 |
0.325 |
|
2006 |
Hébert TE, Galés C, Rebois RV. Detecting and imaging protein-protein interactions during G protein-mediated signal transduction in vivo and in situ by using fluorescence-based techniques. Cell Biochemistry and Biophysics. 45: 85-109. PMID 16679566 DOI: 10.1385/Cbb:45:1:85 |
0.441 |
|
2006 |
Dupré DJ, Hébert TE. Biosynthesis and trafficking of seven transmembrane receptor signalling complexes. Cellular Signalling. 18: 1549-59. PMID 16677801 DOI: 10.1016/J.Cellsig.2006.03.009 |
0.453 |
|
2006 |
Boivin B, Lavoie C, Vaniotis G, Baragli A, Villeneuve LR, Ethier N, Trieu P, Allen BG, Hébert TE. Functional beta-adrenergic receptor signalling on nuclear membranes in adult rat and mouse ventricular cardiomyocytes. Cardiovascular Research. 71: 69-78. PMID 16631628 DOI: 10.1016/J.Cardiores.2006.03.015 |
0.778 |
|
2006 |
Maguy A, Hebert TE, Nattel S. Involvement of lipid rafts and caveolae in cardiac ion channel function. Cardiovascular Research. 69: 798-807. PMID 16405931 DOI: 10.1016/J.Cardiores.2005.11.013 |
0.302 |
|
2006 |
Roy AA, Baragli A, Bernstein LS, Hepler JR, Hébert TE, Chidiac P. RGS2 interacts with Gs and adenylyl cyclase in living cells. Cellular Signalling. 18: 336-48. PMID 16095880 DOI: 10.1016/J.Cellsig.2005.05.004 |
0.465 |
|
2006 |
Hébert TE, Northup JK, Rebois RV. Signal Transduction Mediated by Heptahelical Receptors and Heterotrimeric G Proteins Reviews in Cell Biology and Molecular Medicine. DOI: 10.1002/3527600906.Mcb.200500035 |
0.499 |
|
2005 |
Guimond J, Mamarbachi AM, Allen BG, Rindt H, Hébert TE. Role of specific protein kinase C isoforms in modulation of beta1- and beta2-adrenergic receptors. Cellular Signalling. 17: 49-58. PMID 15451024 DOI: 10.1016/J.Cellsig.2004.05.012 |
0.425 |
|
2004 |
Ehrlich JR, Pourrier M, Weerapura M, Ethier N, Marmabachi AM, Hébert TE, Nattel S. KvLQT1 modulates the distribution and biophysical properties of HERG. A novel alpha-subunit interaction between delayed rectifier currents. The Journal of Biological Chemistry. 279: 1233-41. PMID 14585842 DOI: 10.1074/Jbc.M309087200 |
0.324 |
|
2004 |
Rebois RV, Allen BG, Hébert TE. The targetable G protein proteome: Where is the next generation of drug targets? Drug Discovery Today: Targets. 3: 104-111. DOI: 10.1016/S1741-8372(04)02429-6 |
0.445 |
|
2003 |
Rebois RV, Hébert TE. Protein complexes involved in heptahelical receptor-mediated signal transduction. Receptors & Channels. 9: 169-94. PMID 12775338 |
0.353 |
|
2003 |
Lavoie C, Hébert TE. Pharmacological characterization of putative beta1-beta2-adrenergic receptor heterodimers. Canadian Journal of Physiology and Pharmacology. 81: 186-95. PMID 12710533 DOI: 10.1139/Y02-167 |
0.448 |
|
2003 |
Rebois RV, Hébert TE. Protein complexes involved in heptahelical receptor-mediated signal transduction. Receptors & Channels. 9: 169-194. DOI: 10.3109/10606820308243 |
0.457 |
|
2002 |
Lavine N, Ethier N, Oak JN, Pei L, Liu F, Trieu P, Rebois RV, Bouvier M, Hebert TE, Van Tol HH. G protein-coupled receptors form stable complexes with inwardly rectifying potassium channels and adenylyl cyclase. The Journal of Biological Chemistry. 277: 46010-9. PMID 12297500 DOI: 10.1074/Jbc.M205035200 |
0.479 |
|
2002 |
Thiyagarajan MM, Bigras E, Van Tol HH, Hébert TE, Evanko DS, Wedegaertner PB. Activation-induced subcellular redistribution of G alpha(s) is dependent upon its unique N-terminus. Biochemistry. 41: 9470-84. PMID 12135370 DOI: 10.1021/Bi025533U |
0.303 |
|
2001 |
Lemire I, Ducharme A, Tardif JC, Poulin F, Jones LR, Allen BG, Hébert TE, Rindt H. Cardiac-directed overexpression of wild-type alpha1B-adrenergic receptor induces dilated cardiomyopathy. American Journal of Physiology. Heart and Circulatory Physiology. 281: H931-8. PMID 11454600 DOI: 10.1152/Ajpheart.2001.281.2.H931 |
0.349 |
|
2001 |
Hébert TE. Signalling in cardiac disease: the molecular deficit at the heart of the problem. Cardiovascular Research. 50: 7-9. PMID 11282073 DOI: 10.1016/S0008-6363(01)00234-6 |
0.352 |
|
2000 |
Robillard L, Ethier N, Lachance M, Hébert TE. Gβγ subunit combinations differentially modulate receptor and effector coupling in vivo Cellular Signalling. 12: 673-682. PMID 11080620 DOI: 10.1016/S0898-6568(00)00118-2 |
0.464 |
|
1999 |
Gaspo R, Sun H, Fareh S, Levi M, Yue L, Allen BG, Hebert TE, Nattel S. Dihydropyridine and beta adrenergic receptor binding in dogs with tachycardia-induced atrial fibrillation Cardiovascular Research. 42: 434-442. PMID 10533579 DOI: 10.1016/S0008-6363(99)00036-X |
0.353 |
|
1999 |
Lachance M, Ethier N, Wolbring G, Schnetkamp PPM, Hébert TE. Stable association of G proteins with β2AR is independent of the state of receptor activation Cellular Signalling. 11: 523-533. PMID 10405763 DOI: 10.1016/S0898-6568(99)00024-8 |
0.481 |
|
1999 |
Ng GY, Clark J, Coulombe N, Ethier N, Hebert TE, Sullivan R, Kargman S, Chateauneuf A, Tsukamoto N, McDonald T, Whiting P, Mezey E, Johnson MP, Liu Q, Kolakowski LF, et al. Identification of a GABAB receptor subunit, gb2, required for functional GABAB receptor activity. The Journal of Biological Chemistry. 274: 7607-10. PMID 10075644 DOI: 10.1074/jbc.274.12.7607 |
0.349 |
|
1998 |
Lemire I, Allen BG, Rindt H, Hebert TE. Cardiac-specific overexpression of α(1B)AR regulates βAR activity via molecular crosstalk Journal of Molecular and Cellular Cardiology. 30: 1827-1839. PMID 9769238 DOI: 10.1006/Jmcc.1998.0746 |
0.369 |
|
1998 |
Hebert TE, Loisel TP, Adam L, Ethier N, Onge SS, Bouvier M. Functional rescue of a constitutively desensitized beta2AR through receptor dimerization. The Biochemical Journal. 330: 287-93. PMID 9461522 DOI: 10.1042/Bj3300287 |
0.347 |
|
1998 |
Hébert TE, Bouvier M. Structural and functional aspects of G protein-coupled receptor oligomerization Biochemistry and Cell Biology. 76: 1-11. DOI: 10.1139/o98-012 |
0.407 |
|
1996 |
Loisel TP, Adam L, Hebert TE, Bouvier M. Agonist stimulation increases the turnover rate of beta 2AR-bound palmitate and promotes receptor depalmitoylation. Biochemistry. 35: 15923-32. PMID 8961959 DOI: 10.1021/Bi9611321 |
0.439 |
|
1996 |
Hebert TE, Moffett S, Morello JP, Loisel TP, Bichet DG, Barret C, Bouvier M. A peptide derived from a beta2-adrenergic receptor transmembrane domain inhibits both receptor dimerization and activation. The Journal of Biological Chemistry. 271: 16384-92. PMID 8663163 DOI: 10.1074/Jbc.271.27.16384 |
0.457 |
|
1995 |
Bouvier M, Loisel TP, Hebert T. Dynamic regulation of G-protein coupled receptor palmitoylation: potential role in receptor function. Biochemical Society Transactions. 23: 577-81. PMID 8566420 DOI: 10.1042/Bst0230577 |
0.459 |
|
1995 |
Bouvier M, Moffett S, Loisel TP, Mouillac B, Hebert T, Chidiac P. Palmitoylation of G-protein-coupled receptors: a dynamic modification with functional consequences. Biochemical Society Transactions. 23: 116-20. PMID 7758677 DOI: 10.1042/Bst0230116 |
0.378 |
|
1995 |
Bouvier M, Chidiac P, Hebert TE, Loisel TP, Moffett S, Mouillac B. Dynamic palmitoylation of G-protein-coupled receptors in eukaryotic cells. Methods in Enzymology. 250: 300-14. PMID 7651160 DOI: 10.1016/0076-6879(95)50080-4 |
0.5 |
|
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